Compounds > enkephalin, leucine

enkephalin, leucine and metkephamid

enkephalin, leucine has been researched along with metkephamid in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bose, R; Glavin, GB; Hall, A; Pinsky, C1
Ling, GS; Lockhart, SH; Pasternak, GW; Spiegel, K1
Calimlim, JF; Cox, C; Lasagna, L; Sriwatanakul, K; Wardell, WM1
Bemis, KG; Frederickson, RC; Shuman, R; Smithwick, EL1
Adler, MW; Cowan, A; Tortella, FC1
Nagasaka, H; Yaksh, TL1

Trials

1 trial(s) available for enkephalin, leucine and metkephamid

ArticleYear
Analgesic efficacy of parenteral metkephamid acetate in treatment of postoperative pain.
    Lancet (London, England), 1982, Jun-19, Volume: 1, Issue:8286

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Endorphins; Enkephalin, Methionine; Enkephalins; Humans; Injections, Intramuscular; Meperidine; Middle Aged; Pain, Postoperative; Random Allocation

1982

Other Studies

5 other study(ies) available for enkephalin, leucine and metkephamid

ArticleYear
Opioid involvement in epileptogenic and neurovisceral activity.
    Progress in clinical and biological research, 1990, Volume: 328

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Digestive System; Enkephalin, Leucine; Enkephalin, Methionine; Epilepsy; Kainic Acid; Male; Mice; Naloxone; Nervous System; Pyrrolidines; Receptors, Opioid

1990
Separation of opioid analgesia from respiratory depression: evidence for different receptor mechanisms.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Analgesia; Animals; Blood Gas Analysis; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Respiration

1985
Metkephamid, a systemically active analog of methionine enkephalin with potent opioid alpha-receptor activity.
    Science (New York, N.Y.), 1981, Feb-06, Volume: 211, Issue:4482

    Topics: Analgesics; Animals; Brain; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Humans; Kinetics; Male; Mice; Rats; Receptors, Opioid; Structure-Activity Relationship; Substance-Related Disorders

1981
A comparison of the anticonvulsant effects of two systemically active enkephalin analogues in rats.
    European journal of pharmacology, 1981, Apr-24, Volume: 71, Issue:1

    Topics: Animals; Anticonvulsants; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Flurothyl; Male; Naloxone; Rats; Seizures

1981
Effects of intrathecal mu, delta, and kappa agonists on thermally evoked cardiovascular and nociceptive reflexes in halothane-anesthetized rats.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Anesthesia, Inhalation; Animals; Blood Pressure; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Halothane; Heart Rate; Hot Temperature; Injections, Spinal; Male; Morphine; Nalbuphine; Nociceptors; Pain Threshold; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Reflex; Thiophenes

1995