enkephalin, leucine has been researched along with leucine in 111 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 68 (61.26) | 18.7374 |
1990's | 22 (19.82) | 18.2507 |
2000's | 12 (10.81) | 29.6817 |
2010's | 6 (5.41) | 24.3611 |
2020's | 3 (2.70) | 2.80 |
Authors | Studies |
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Dray, F; Gros, C; Lafon-Cazal, M | 1 |
Frenk, H; Liebeskind, JC; Urca, G | 1 |
Aliautdin, RN; Chichenkov, ON; Fisenko, VP | 1 |
Huidobro, F; Huidobro-Toro, JP; Miranda, H | 1 |
Childers, S; Larsson, LI; Snyder, SH | 1 |
Dolganov, GM; Efimov, VA; Monastyrskaia, GS; Ovchinnikov, IuA; Sverdlov, ED | 1 |
Chichenkov, ON; Fisenko, VP; Novikov, NN | 1 |
Di Giulio, AM; Majane, EM; Yang, HY | 1 |
Frederickson, RC; Richter, JA; Wesche, DL | 1 |
Guarneri, M; Salvadori, S; Tomatis, R | 1 |
Bhargava, HN | 1 |
Kosterlitz, HW; Leslie, FM; Ling, N; Lord, JA; Waterfield, AA | 1 |
Kullmann, W | 1 |
Davis, WG; Delaney, PV; Tormey, WP | 1 |
Dray, F; Gros, C; Humbert, J; Pradelles, P | 1 |
Hughes, J; Kosterlitz, HW; McKnight, AT; Sosa, RP | 1 |
Hughes, J; Kosterlitz, HW; Smith, TW | 1 |
Costa, E; Hong, JS; Yang, HY | 1 |
Salvadori, S; Tomatis, R | 1 |
Bawab, W; Crine, P; DesGroseillers, L; Querido, E | 1 |
Aungst, BJ; Hussain, MA | 1 |
Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mantelet, S | 1 |
Goodman, M; Said-Nejad, OE; Schiller, PW; Yamazaki, T | 1 |
Baas, AA; Dzoljic, MM; Dzoljic, MR; Rupreht, J; Ukponmwan, OE; van den Berg, DJ | 1 |
Ishikawa, K; Martinez, JL; Shibanoki, S; Weinberger, SB | 1 |
Ayala, JM; Molineaux, CJ | 1 |
Costentin, J; Dourmap, N; Michael-Titus, A; Schwartz, JC | 1 |
Beniston, D; Bennett, EL; Ishikawa, K; Martinez, JL; Nudelman, KA; Rosenzweig, MR; Schulteis, G; Shibanoki, S; Weinberger, SB | 1 |
Beliaev, NA; Kelesheva, LF; Kolesanova, EF; Panchenko, LF; Rotanova, TV | 1 |
Giros, B; Llorens-Cortes, C; Quach, TT; Schwartz, JC; Van Amsterdam, JG | 1 |
Herz, A; Parsons, CG | 1 |
Gerothanassis, IP; Karayannis, T; Marraud, M; Sakarellos, C; Sakarellos-Daitsiotis, M | 1 |
Aungst, BJ; Hussain, MA; Koval, CA; Shenvi, AB | 1 |
Caline, H; Costentin, J; Dourmap, N; Michael-Titus, A; Schwartz, JC | 1 |
Livett, BG; Marley, PD; Mitchelhill, KI | 1 |
Martinez, JL; Weinberger, SB | 1 |
Altiere, RJ; Crooks, PA; Gillespie, MN; Krechniak, JW; Olson, JW | 1 |
Giros, B; Gros, C; Llorens-Cortes, C; Schwartz, JC | 1 |
Barchas, JD; Evans, CJ; Hurlbut, DE; Leslie, FM | 1 |
Bausback, HH; Churchill, L; Palmieri, FE; Ward, PE | 1 |
Martinez, JL; Walker, RC; Weinberger, SB; Zafuto, CE | 1 |
Gros, C; Llorens-Cortes, C; Schwartz, JC | 2 |
Hammonds, RG; Li, CH; Westphal, M | 1 |
Kameyama, T; Katoh, A; Nabeshima, T | 1 |
Dzoljić, E; Varagić, VM | 1 |
Dickenson, AH; Fournie-Zaluski, MC; Roques, BP; Sullivan, AF | 1 |
Carson, LW; Kashi, SD; Lee, VH; Stratford, RE | 1 |
Audus, KL; Baranczyk-Kuzma, A | 1 |
Bouboutou, R; Bourgoin, S; Cesselin, F; Devin, J; Fournie-Zaluski, MC; Hamon, M; Roques, B; Waksman, G | 1 |
Han, JS; Yuan, H | 1 |
Han, JS; Jin, WQ; Zhou, ZF | 1 |
Bailey, C; Kitchen, I | 1 |
Iwama, T; Satoh, M; Takagi, H; Wada, T | 1 |
Ishida, J; Kai, M; Ohkura, Y | 1 |
Chaillet, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Zajac, JM | 1 |
Aoki, K; Kajiwara, M; Oka, T | 1 |
Herkenham, M; Pert, CB | 1 |
Basbaum, AI; Moss, MS | 1 |
Bakalkin, GIa; Iarygin, KN; Smirnov, VN; Titov, MI; Trushina, ED | 1 |
Bui, ND; Deschodt-Lanckman, M | 1 |
Corbett, AD; Kosterlitz, HW; McKnight, AT | 1 |
Chaillet, P; Costentin, J; de la Baume, S; Marcais-Collado, H; Schwartz, JC; Yi, CC | 3 |
Chaillet, P; Costentin, J; Coulaud, A; Fournié-Zaluski, MC; Gacel, G; Roques, BP | 1 |
Brandt, U; Lentzen, H; Palenker, J | 1 |
Lentzen, H; Palenker, J | 1 |
Geary, LE; Kerchner, GA | 1 |
Carenzi, A; Della Bella, D; Frigeni, V; Reggiani, A | 1 |
Bouboutou, R; Chaillet, P; Cherot, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Waksman, G | 1 |
Chaillet, P; Costentin, J; Lecomte, JM; Marçais, H; Natan, LB; Uchida, G | 1 |
Llorens-Cortes, C; Schwartz, JC | 1 |
Davis, KR; Hernandez, DE; Wolfenden, R | 1 |
Costa, E; Yang, HY; Zhang, AZ | 1 |
Cohen, ML; Geary, LE; Wiley, KS | 1 |
Hazato, T; Kasama, A; Katayama, T; Kaya, K; Nishioka, S; Shimamura, M | 1 |
Bulgakov, SA; Polonskiĭ, VM; Shatalov, VN; Smagin, VG; Vinogradov, VA | 1 |
Jeffcoate, WJ | 1 |
Hazato, T; Inagaki-Shimamura, M; Katayama, T; Yamamoto, T | 1 |
Barbeau, A; Izumi, K; Munekata, E; Nakanishi, T; Wong, P; Yamamoto, H; Yoshida, M | 1 |
Barbeau, A; Izumi, K; Munekata, E; Nakanishi, T; Yamamoto, H | 1 |
Baronets, VIu; Beliaev, NA; Kolesanova, EF; Panchenko, LF | 1 |
Billington, D; MacKinnon, KL; Zuzel, KA | 1 |
Grupp, LA; Harding, S; Szczepanska, R | 1 |
Ayukawa, K; Murata, J; Ogasawara, M; Saimi, I | 1 |
Boileau, G; Cohen, P; Crine, P; Dion, N | 1 |
Ekström, G; Krondahl, E; Lennernäs, H; Orzechowski, A | 1 |
Anderson, L; Bussler, B; Dufton, M; Martins, H | 1 |
Abramić, M; Balog, T; Hrsak, I; Marotti, T; Svoboda-Beusen, I | 1 |
Cudić, MB; Hollósi, M; Horvat, S; Kojić-Prodić, B; Kveder, M; Vass, E | 1 |
Czaplewski, C; Groth, M; Karolczak, J; Liwo, A; Malicka, J; Wiczk, W | 1 |
Czaplewski, C; Ganzynkowicz, R; Groth, M; Karolczak, J; Liwo, A; Malicka, J; Wiczk, W | 1 |
Hojo, K; Kawasaki, K; Maeda, M | 1 |
Johnson, SW; Zheng, F | 1 |
Bellier, B; Bossée, A; Fournier, F; Tabet, JC; Tasseau, O | 1 |
Abdali, S; Bohr, H; Nielsen, OF; Refstrup, P | 1 |
Chalmers, MJ; Cooper, HJ; Heil, M; Hendrickson, CL; Marshall, AG; Schäfer, M; Schmuck, C | 1 |
Afonso, C; Bellier, B; Bossée, A; Fournier, F; Pepe, C; Tabet, JC; Tasseau, O | 1 |
Borisov, OV; Rakov, VS; Whitehouse, CM | 1 |
Albiston, AL; Ascher, DB; Chai, SY; Lew, RA; Morton, CJ; Parker, MW; Ye, S | 1 |
Kennedy, RT; Lee, MS; Li, Q; Pei, J; Valaskovic, GA | 1 |
Bari, S; Gonzalez-Magaña, O; Hoekstra, R; Reitsma, G; Schippers, S; Schlathölter, T; Werner, J | 1 |
Fournie-Zaluski, MC; Gore, C; Labuz, D; Machelska, H; Roques, BP; Schreiter, A; Stein, C | 1 |
Canon, F; Cerovski, VZ; Giuliani, A; Milosavljević, AR; Nahon, L | 1 |
Katsuyama, S; Komatsu, T; Mizoguchi, H; Sakurada, C; Sakurada, S; Sakurada, T; Tsuzuki, M | 1 |
Jordanova, A; Lalchev, Z; Tsanova, A | 1 |
Canon, F; Giuliani, A; Milosavljević, AR; Nahon, L; Ranković, MLj | 1 |
Bagley, EE; Gregoriou, GC; Patel, SD; Winters, BL | 1 |
Arslanian, AJ; Dearden, DV; Mismash, N | 1 |
Ganesh, CB; Ganeyan, A | 1 |
1 review(s) available for enkephalin, leucine and leucine
Article | Year |
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Brain peptides and pain sensation.
Topics: Animals; beta-Lipotropin; Brain Chemistry; Endorphins; Enkephalins; Fluorescent Antibody Technique; Guinea Pigs; Humans; Leucine; Methionine; Mice; Morphine; Narcotics; Pain; Peptides; Radioimmunoassay; Rats | 1980 |
110 other study(ies) available for enkephalin, leucine and leucine
Article | Year |
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[Presence of substances immunoreactively related to enkephalin in an insect, Locusta migratoria].
Topics: Animals; Chromatography, Gel; Endorphins; Enkephalins; Female; Grasshoppers; Leucine; Male; Methionine; Molecular Weight; Nervous System; Radioimmunoassay; Tissue Distribution | 1978 |
Epileptic properties of leucine- and methionine-enkephalin: comparison with morphine and reversibility by naloxone.
Topics: Animals; Dose-Response Relationship, Drug; Electroencephalography; Endorphins; Enkephalins; Injections, Intraventricular; Leucine; Male; Methionine; Morphine; Naloxone; Rats; Receptors, Opioid; Seizures | 1978 |
[Effect of leucine-enkephalin on the interneuronal transmission of excitation].
Topics: Animals; Cats; Central Nervous System; Drug Interactions; Electric Stimulation; Endorphins; Enkephalins; Evoked Potentials; Female; Leucine; Male; Methysergide; Naloxone; Synaptic Transmission | 1979 |
Evidence for morphine and morphine-like alkaloid responses resistant to naloxone blockade in the rat vas deferens.
Topics: Animals; Drug Tolerance; Electric Stimulation; Enkephalins; In Vitro Techniques; Leucine; Male; Morphine; Morphine Derivatives; Muscle Contraction; Naloxone; Narcotics; Placebos; Rats; Receptors, Opioid; Vas Deferens | 1979 |
Met- and Leu-enkephalin immunoreactivity in separate neurones.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Brain; Cats; Endorphins; Enkephalins; Immunologic Techniques; Intestine, Small; Leucine; Methionine; Models, Biological; Myenteric Plexus | 1979 |
[Synthesis of the leucine-enkephalin gene, its cloning and expression in Escherichia coli].
Topics: Base Sequence; Cloning, Molecular; DNA, Recombinant; Endorphins; Enkephalins; Escherichia coli; Genes; Genetic Engineering; Genetic Vectors; Leucine; Plasmids | 1979 |
[Effect of leucine-enkephalin on the neuronal activity of the cerebral cortex].
Topics: Action Potentials; Animals; Cerebral Cortex; Endorphins; Enkephalins; Leucine; Neural Inhibition; Neurons; Rats; Somatosensory Cortex; Time Factors | 1979 |
On the distribution of [met5]- and [leu5]-enkephalins in the brain of the rat, guinea-pig and calf.
Topics: Animals; Brain Chemistry; Cattle; Cerebral Cortex; Corpus Striatum; Endorphins; Enkephalins; Guinea Pigs; Hippocampus; Hypothalamus; Leucine; Male; Methionine; Radioimmunoassay; Rats; Species Specificity; Tissue Distribution | 1979 |
K-stimulated release of leu- and met-enkephalin from rat striatal slices: lack of effect of morphine and naloxone.
Topics: Animals; Calcium; Corpus Striatum; Endorphins; Enkephalins; In Vitro Techniques; Leucine; Magnesium; Male; Methionine; Morphine; Naloxone; Potassium; Radioimmunoassay; Rats | 1979 |
Use of iminodiacetic acid for the synthesis of piperazinyl peptides related to leu-enkephalin. II.
Topics: Animals; Endorphins; Enkephalins; Glycine; Guinea Pigs; Ileum; Imino Acids; Leucine; Male; Mice; Peptides; Piperazines; Vas Deferens | 1979 |
Studies of the possible role of brain endorphins in pentobarbital anesthesia and toxicity in mice.
Topics: Animals; Brain; Endorphins; Enkephalins; Leucine; Male; Mice; Morphine; Naloxone; Naltrexone; Pentobarbital; Phenylalanine | 1979 |
Opioid activities of fragments of beta-endorphin and of its leucine65-analogue. Comparison of the binding properties of methionine- and leucine-enkephalin.
Topics: Animals; beta-Lipotropin; Brain; Brain Chemistry; Endorphins; Enkephalins; Guinea Pigs; In Vitro Techniques; Leucine; Ligands; Methionine; Mice; Muscle Contraction; Swine | 1979 |
Enzymatic synthesis of Leu- and Met-enkephalin.
Topics: Amino Acids; Chymotrypsin; Endorphins; Enkephalins; Leucine; Methionine; Methods; Papain | 1979 |
Enkephalins in large bowel malignancy and in acute appendicitis.
Topics: Acute Disease; Adenocarcinoma; Appendicitis; Appendix; Cecal Neoplasms; Colon; Colonic Neoplasms; Endorphins; Enkephalins; Humans; Leucine; Methionine | 1979 |
Enkephalin-like products in embryonic chicken retina.
Topics: Animals; Chick Embryo; Chromatography, High Pressure Liquid; Endorphins; Enkephalins; Leucine; Methionine; Radioimmunoassay; Retina | 1979 |
Incorporation of labelled amino acids into the enkephalins.
Topics: Animals; Brain; Cycloheximide; Endorphins; Enkephalins; Leucine; Male; Methionine; Myenteric Plexus; Protein Precursors; Puromycin; Rats; Tyrosine | 1977 |
The distribution of methionine-enkephalin and leucine-enkephalin in the brain and peripheral tissues.
Topics: Animals; Brain Chemistry; Corpus Striatum; Endorphins; Enkephalins; Guinea Pigs; Hypothalamus; Ileum; Leucine; Methionine; Methods; Mice; Peptides; Pituitary Gland; Rabbits; Rats; Tissue Distribution | 1977 |
Regional distribution of LEU and MET enkephalin in rat brain.
Topics: Animals; Brain Chemistry; Cerebellum; Cerebral Cortex; Corpus Striatum; Enkephalins; Hippocampus; Hypothalamus; Leucine; Medulla Oblongata; Mesencephalon; Methionine; Oligopeptides; Rats | 1977 |
N-terminal Leu-enkephalin rearrangements.
Topics: Chemical Phenomena; Chemistry; Electrophoresis, Paper; Enkephalins; Hydrolysis; Leucine; Oligopeptides; Peptide Chain Termination, Translational | 1977 |
Identification and characterization of aminopeptidases from Aplysia californica.
Topics: Aminopeptidases; Anilides; Aniline Compounds; Animals; Anti-Bacterial Agents; Aplysia; Bacitracin; Chromatography, High Pressure Liquid; Enkephalin, Leucine; FMRFamide; Ganglia; Hemolymph; Kidney; Leucine; Male; Myocardium; Neuropeptides; Oligopeptides; Oviducts; Peptides; Puromycin; Testis | 1992 |
Nasal absorption of leucine enkephalin in rats and the effects of aminopeptidase inhibition, as determined from the percentage of the dose unabsorbed.
Topics: Absorption; Amino Acid Sequence; Aminopeptidases; Animals; Boron Compounds; Enkephalin, Leucine; Half-Life; Leucine; Male; Molecular Sequence Data; Nasal Mucosa; Protease Inhibitors; Rats | 1992 |
Feedback inhibition of met-enkephalin release from the rat spinal cord in vivo.
Topics: Animals; Calcitonin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Feedback; Indoles; Injections, Spinal; Leucine; Male; Morphinans; Naloxone; Naltrexone; Oligopeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan | 1992 |
Conformational studies of stereoisomeric 14-membered cyclic enkephalin analogues containing 1-naphthylalanine at the fourth position: chirality effect of leucine at the fifth position on biological activity and receptor selectivity.
Topics: Alanine; Amino Acid Sequence; Enkephalins; Leucine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Conformation; Receptors, Opioid; Spectrum Analysis; Structure-Activity Relationship; Temperature | 1991 |
Suppressive effects of enkephalins and REM sleep deprivation on seizures.
Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Electroshock; Enkephalins; Glycopeptides; Leucine; Male; Mice; Mice, Inbred Strains; Neprilysin; Nitrous Oxide; Rats; Rats, Inbred Strains; Sleep Deprivation; Sleep, REM; Substance Withdrawal Syndrome; Thiorphan | 1991 |
HPLC-ECD determination of the enzymatic hydrolysis of [leu]- and [met]enkephalin in rat plasma.
Topics: Acetylcholinesterase; Aminopeptidases; Animals; Captopril; CD13 Antigens; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Hydrolysis; In Vitro Techniques; Leucine; Male; Oligopeptides; Rats; Rats, Inbred Strains; Thiorphan; Tyrosine | 1990 |
An inhibitor of endopeptidase-24.15 blocks the degradation of intraventricularly administered dynorphins.
Topics: Animals; Brain; Captopril; Cerebral Ventricles; Choroid Plexus; Dynorphins; Enkephalin, Leucine; Kinetics; Leucine; Male; Metalloendopeptidases; Neprilysin; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains | 1990 |
Role of delta opioid receptors in the effects of inhibitors of enkephalin-degrading peptidases on the horizontal and vertical components of locomotion in mice.
Topics: Aminopeptidases; Animals; CD13 Antigens; Dipeptides; Drug Synergism; Enkephalin, Leucine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Leucine; Locomotion; Male; Mice; Naloxone; Neprilysin; Phenylcarbamates; Prodrugs; Receptors, Opioid; Receptors, Opioid, delta; Sulfhydryl Compounds; Thiorphan | 1990 |
Hydrolysis of [Leu]enkephalin by chick plasma in vitro.
Topics: Aminopeptidases; Animals; Chickens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Enkephalin, Leucine; Hydrolysis; In Vitro Techniques; Leucine; Male; Puromycin | 1991 |
[The effect of the aminopeptidase inhibitor bestatin on the enkephalin level in the rat brain].
Topics: Aminopeptidases; Animals; Brain; Brain Chemistry; Dimethyl Sulfoxide; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Leucine; Male; Rats | 1990 |
Enkephalin biosynthesis and release in mouse striatum are inhibited by GABA receptor stimulation: compared changes in preproenkephalin mRNA and Tyr-Gly-Gly levels.
Topics: Aminooxyacetic Acid; Animals; Corpus Striatum; Diazepam; Enkephalins; Flumazenil; Kinetics; Leucine; Male; Mice; Muscimol; Oligopeptides; Protein Precursors; Receptors, GABA-A; RNA, Messenger | 1990 |
Peripheral opioid receptors mediating antinociception in inflammation. Evidence for activation by enkephalin-like opioid peptides after cold water swim stress.
Topics: Analgesia; Animals; Dioxolanes; Dipeptides; Enkephalins; Inflammation; Leucine; Male; Naloxone; Naltrexone; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological; Swimming; Thiorphan | 1990 |
17O- and 14N-NMR studies of Leu-enkephalin and enkephalin-related fragments in aqueous solution.
Topics: Amino Acid Sequence; Enkephalin, Leucine; Hydrogen-Ion Concentration; Leucine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Weight; Nitrogen Isotopes; Oxygen Isotopes; Peptide Fragments; Protein Conformation; Solutions; Thermodynamics; Water | 1990 |
Recovery of rat nasal mucosa from the effects of aminopeptidase inhibitors.
Topics: Aminopeptidases; Animals; Boron; Boron Compounds; Enkephalin, Leucine; Leucine; Nasal Mucosa; Puromycin; Rats | 1990 |
Role of endogenous enkephalins in locomotion and nociception studied with peptidase inhibitors in two inbred strains of mice (C57BL/6J and DBA/2J).
Topics: Analgesics; Animals; Cerebral Ventricles; Enkephalins; Injections, Intraventricular; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Naloxone; Pain; Protease Inhibitors; Reference Values; Species Specificity; Thiorphan | 1989 |
Effects of opioid peptides containing the sequence of Met5-enkephalin or Leu5-enkephalin on nicotine-induced secretion from bovine adrenal chromaffin cells.
Topics: Adenosine Triphosphate; Adrenal Medulla; Amino Acid Sequence; Animals; Bacitracin; Cattle; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Epinephrine; Guinea Pigs; Leucine; Nicotine; Norepinephrine; Peptide Fragments; Phenanthrolines; Rabbits; Receptors, Opioid; Thiorphan; Tiopronin | 1986 |
Characterization of hydrolysis of [leu]enkephalin and D-ala2-[L-leu]enkephalin in rat plasma.
Topics: Aminopeptidases; Animals; CD13 Antigens; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Half-Life; Hydrolysis; Leucine; Male; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Thiorphan | 1988 |
Pulmonary metabolism of exogenous enkephalins in isolated perfused rat lungs.
Topics: Aminopeptidases; Animals; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; In Vitro Techniques; Leucine; Lung; Male; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
[Opioid peptides: metabolism and receptors].
Topics: Animals; Brain; Cattle; Endopeptidases; Endorphins; Enkephalins; Humans; Leucine; Mice; Neprilysin; Pro-Opiomelanocortin; Protease Inhibitors; Protein Precursors; Receptors, Opioid; Thiorphan; Tiopronin | 1987 |
Pharmacological properties of a proenkephalin A-derived opioid peptide: BAM 18.
Topics: Animals; Biological Assay; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; In Vitro Techniques; Leucine; Male; Naloxone; Protein Precursors; Radioligand Assay; Receptors, Opioid; Structure-Activity Relationship | 1987 |
Kinin and enkephalin conversion by an endothelial, plasma membrane carboxypeptidase.
Topics: 3-Mercaptopropionic Acid; Animals; Carboxypeptidases; Cell Membrane; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Edetic Acid; Endothelium; Enkephalins; Glycopeptides; Hydrogen-Ion Concentration; Kinetics; Kinins; Leucine; Lysine Carboxypeptidase; Microscopy, Phase-Contrast; Muscle, Smooth, Vascular; Phenanthrolines; Puromycin; Swine | 1986 |
Characterization of enkephalin degradation in rat plasma.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Leucine; Enkephalins; Kinetics; Leucine; Male; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin | 1986 |
Evaluation of striatal enkephalin release in vivo from steady state levels and turnover rates of the tripeptide Tyr-Gly-Gly.
Topics: Animals; Anti-Bacterial Agents; Corpus Striatum; Enkephalins; In Vitro Techniques; Kinetics; Leucine; Male; Mice; Oligopeptides; Pentobarbital; Thiorphan; Tiopronin | 1986 |
Protease inhibition increases the analgesic potency of peptide E.
Topics: Analgesics; Animals; Bacitracin; beta-Endorphin; Drug Synergism; Endorphins; Enkephalins; Injections, Intraventricular; Leucine; Male; Mice; Peptides; Protease Inhibitors | 1985 |
Inhibition of enkephalin degradation attenuated stress-induced motor suppression (conditioned suppression of motility).
Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Enkephalins; Leucine; Male; Metalloendopeptidases; Mice; Motor Activity; Naloxone; Neprilysin; Pimozide; Stress, Physiological; Thiorphan; Tiopronin | 1988 |
Effects of bestatin and phosphoramidon on the hypertensive response to physostigmine in the rat.
Topics: Animals; Antibiotics, Antineoplastic; Blood Pressure; Carotid Arteries; Catecholamines; Enkephalin, Leucine; Female; Glycopeptides; Injections, Intra-Arterial; Leucine; Male; Naloxone; Physostigmine; Rats; Rats, Inbred Strains | 1987 |
Prevention of degradation of endogenous enkephalins produces inhibition of nociceptive neurones in rat spinal cord.
Topics: Action Potentials; Animals; Dipeptides; Enkephalins; Leucine; Male; Naloxone; Nerve Fibers; Neural Inhibition; Neurons, Afferent; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Tiopronin | 1987 |
Metabolic and permeation barriers to the ocular absorption of topically applied enkephalins in albino rabbits.
Topics: Absorption; Administration, Topical; Animals; Enkephalins; Eye; Leucine; Male; Permeability; Rabbits | 1986 |
Characteristics of aminopeptidase activity from bovine brain microvessel endothelium.
Topics: Aminopeptidases; Animals; Blood-Brain Barrier; Brain; Cattle; Cell Membrane; Cells, Cultured; Endothelium, Vascular; Enkephalins; Kidney; Leucine; Neuropeptides; Puromycin | 1987 |
In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain.
Topics: Aminopeptidases; Animals; Brain; Brain Chemistry; Corpus Striatum; Dipeptides; Enkephalin, Methionine; Enkephalins; Hydrolysis; In Vitro Techniques; Leucine; Mice; Protease Inhibitors; Rats; Thiorphan; Tiopronin | 1985 |
[Electroacupuncture accelerates the biogenesis of central enkephalins in the rat].
Topics: Acupuncture Therapy; Aminopeptidases; Animals; Brain; Electric Stimulation Therapy; Enkephalin, Leucine; Enkephalin, Methionine; Female; Leucine; Male; Phenylalanine; Radioimmunoassay; Rats; Thiorphan; Tiopronin; Transcutaneous Electric Nerve Stimulation | 1985 |
Study of endogenous Tyr-Gly-Gly, a putative enkephalin metabolite, in mouse brain: validation of a radioimmunoassay, localisation and effects of peptidase inhibitors.
Topics: Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Mice; Microwaves; Nalorphine; Neprilysin; Oligopeptides; Protease Inhibitors; Radioimmunoassay; Thiorphan; Tiopronin | 1985 |
[Inhibition of enkephalins degradation in the nucleus accumbens leads to potentiation of acupuncture and morphine analgesia].
Topics: Acupuncture Therapy; Aminopeptidases; Analgesia; Animals; Electric Stimulation Therapy; Endopeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Morphine; Neprilysin; Nucleus Accumbens; Protease Inhibitors; Rabbits; Septal Nuclei; Thiorphan; Tiopronin; Transcutaneous Electric Nerve Stimulation | 1985 |
Determination of proenkephalin products in brain tissue by high-performance liquid chromatography and a modified bioassay procedure.
Topics: Animals; Biological Assay; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Electric Stimulation; Endorphins; Enkephalins; In Vitro Techniques; Leucine; Male; Mice; Muscle Contraction; Muscle, Smooth; Protein Precursors | 1985 |
Sites of analgesic actions of kyotorphin and D-kyotorphin in the central nervous system of rats.
Topics: Analgesics; Animals; Central Nervous System; Endorphins; Enkephalins; Leucine; Male; Naloxone; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reticular Formation; Spinal Cord | 1985 |
Determination of p-hydroxybestatin in human serum by high-performance liquid chromatography using fluorescence detection.
Topics: Chemical Phenomena; Chemistry; Child; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Leucine; Muscular Dystrophies; Spectrometry, Fluorescence; Temperature | 1985 |
The mu rather than the delta subtype of opioid receptors appears to be involved in enkephalin-induced analgesia.
Topics: Analgesics; Animals; Enkephalin, Leucine; Enkephalins; Guinea Pigs; In Vitro Techniques; Leucine; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Nalorphine; Naloxone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thiorphan; Tiopronin | 1984 |
The role of bestatin-sensitive aminopeptidase, angiotensin converting enzyme and thiorphan-sensitive "enkephalinase" in the potency of enkephalins in the guinea-pig ileum.
Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin | 1984 |
Mosaic distribution of opiate receptors, parafascicular projections and acetylcholinesterase in rat striatum.
Topics: Acetylcholinesterase; Animals; Axonal Transport; Caudate Nucleus; Corpus Striatum; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Leucine; Naloxone; Proline; Rats; Receptors, Opioid | 1981 |
The peptidergic organization of the cat periaqueductal gray. II. The distribution of immunoreactive substance P and vasoactive intestinal polypeptide.
Topics: Animals; Cats; Enkephalins; Gastrointestinal Hormones; Leucine; Periaqueductal Gray; Substance P; Vasoactive Intestinal Peptide | 1983 |
[Preferential development of flexion of the left or right hindlimb as a result of treatment with methionine-enkephalin or leucine-enkephalin, respectively].
Topics: Animals; Dominance, Cerebral; Endorphins; Enkephalins; Hindlimb; Leucine; Methionine; Naloxone; Posture; Rats; Receptors, Opioid; Structure-Activity Relationship | 1980 |
Cholecystokinin octa- and tetrapeptide degradation by synaptic membranes. I. Evidence for competition with enkephalins for in vitro common degradation pathways.
Topics: Aminopeptidases; Animals; Cholecystokinin; Chromatography, DEAE-Cellulose; Endorphins; Enkephalin, Leucine; Enkephalins; Gastrins; Kinetics; Leucine; Male; Peptide Fragments; Rats; Sincalide; Synaptic Membranes; Tetragastrin; Tryptophan | 1981 |
Increase in potencies of opioid peptides after peptidase inhibition.
Topics: Animals; beta-Endorphin; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Leucine; Male; Mice; Myenteric Plexus; Protease Inhibitors; Rats; Rats, Inbred Strains; Vas Deferens | 1983 |
Participation of both 'enkephalinase' and aminopeptidase activities in the metabolism of endogenous enkephalins.
Topics: Aminopeptidases; Animals; Corpus Striatum; Endopeptidases; Enkephalins; Leucine; Male; Neprilysin; Nociceptors; Rats; Rats, Inbred Strains; Sensory Thresholds; Synaptic Transmission | 1983 |
Pain control by endogenous enkephalins is mediated by mu opioid receptors.
Topics: Amino Acids, Sulfur; Analgesia; Animals; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Pain; Protease Inhibitors; Receptors, Opioid; Receptors, Opioid, mu; Thiorphan; Tiopronin | 1983 |
Enkephalin degradation by enkephalinergic neuroblastoma cells. Involvement of angiotensin-converting-enzyme.
Topics: Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Cell Membrane; Cells, Cultured; Enkephalin, Leucine; Hydrolysis; Leucine; Mice; Neuroblastoma; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin | 1984 |
Localization of the thiorphan-sensitive endopeptidase, termed enkephalinase A, on glial cells.
Topics: Aminopeptidases; Animals; Astrocytes; Brain; Cell Membrane; Cells, Cultured; Endopeptidases; Enkephalin, Leucine; Kinetics; Leucine; Neprilysin; Protease Inhibitors; Rats; Thiorphan; Tiopronin | 1983 |
Studies on the transport of enkephalin-like oligopeptides in rat intestinal mucosa.
Topics: Aminopeptidases; Animals; Biological Transport, Active; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Male; Oligopeptides; Puromycin; Rats; Rats, Inbred Strains; Tyrosine | 1983 |
Peptidases involved in the inactivation of exogenous and endogenous enkephalins.
Topics: Aminopeptidases; Animals; Brain; Endopeptidases; Enkephalins; Leucine; Mice; Neprilysin; Nociceptors; Rats; Thiorphan; Tiopronin | 1983 |
Effect of inhibition of neuropeptidases on the pain threshold of mice and rats.
Topics: Aminopeptidases; Animals; Endopeptidases; Enkephalin, Leucine; Leucine; Male; Mice; Neprilysin; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Sensory Thresholds; Species Specificity; Thiorphan; Tiopronin | 1983 |
Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes.
Topics: Aminopeptidases; Analgesics; Animals; Brain; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kidney; Leucine; Neprilysin; Protease Inhibitors; Rabbits; Rats; Reaction Time; Thiorphan; Tiopronin | 1984 |
Inhibition of enkephalin metabolism by, and antinociceptive activity of, bestatin, an aminopeptidase inhibitor.
Topics: Aminopeptidases; Analgesics; Animals; Brain; Drug Synergism; Enkephalins; Hydrolysis; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred Strains; Puromycin; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin | 1983 |
Involvement of endogenous enkephalins in the mouse 'behavioral despair' test.
Topics: Aminopeptidases; Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Motor Activity; Naloxone; Protease Inhibitors; Thiorphan; Tiopronin | 1984 |
Changes in turnover of cerebral monoamines following inhibition of enkephalin metabolism by thiorphan and bestatin.
Topics: alpha-Methyltyrosine; Amino Acids, Sulfur; Aminopeptidases; Animals; Biogenic Amines; Brain; Enkephalins; Leucine; Male; Methyltyrosines; Mice; Naloxone; Protease Inhibitors; Thiorphan; Tiopronin | 1984 |
Leucinal inhibits brain aminopeptidase activity and potentiates analgesia induced by leu-enkephalen.
Topics: Aminopeptidases; Analgesia; Animals; Brain; Chemical Phenomena; Chemistry; Enkephalin, Leucine; Leucine; Male; Mice; Nociceptors; Rats; Rats, Inbred Strains | 1983 |
Nociception, enkephalin content and dipeptidyl carboxypeptidase activity in brain of mice treated with exopeptidase inhibitors.
Topics: Animals; Brain; Corpus Striatum; Endopeptidases; Enkephalin, Methionine; Enkephalins; Exopeptidases; Female; Leucine; Mice; Neprilysin; Nociceptors; Protease Inhibitors; Thiorphan; Tiopronin | 1982 |
Enkephalin degradation in the guinea-pig ileum: effect of aminopeptidase inhibitors, puromycin and bestatin.
Topics: Aminopeptidases; Animals; Enkephalins; Guinea Pigs; Ileum; Leucine; Male; Puromycin | 1983 |
Enkephalin degrading enzymes in cerebrospinal fluid.
Topics: Cerebrospinal Fluid; Enkephalins; Humans; Kinetics; Leucine; Protease Inhibitors | 1983 |
[Inhibitory effect of leu-enkephalin on gastric secretion in dogs].
Topics: Animals; Anura; Denervation; Dogs; Endorphins; Enkephalins; Gastric Juice; Gastric Mucosa; Gastrins; Hydrogen-Ion Concentration; In Vitro Techniques; Leucine; Rana temporaria; Stomach; Time Factors | 1980 |
Separation and characterization of a dipeptidyl aminopeptidase that degrades enkephalins from monkey brain.
Topics: Aminopeptidases; Animals; Brain; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Endorphins; Enkephalins; Leucine; Macaca fascicularis; Puromycin | 1982 |
Central neuropharmacology of D-Ala2-Met-enkephalinamide and its interactions with taurine in rats.
Topics: Analgesia; Animals; Catatonia; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Humans; Leucine; Male; Rats; Rats, Inbred Strains; Seizures; Taurine | 1981 |
Effects of taurine and gamma-aminobutyric acid on akinesia and analgesia induced by D-Ala2-Met-enkephalinamide in rats.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Kinetics; Leucine; Male; Movement; Rats; Taurine | 1980 |
[Some features of enkephalin metabolism in the rat brain after administration of bestatin].
Topics: Aminopeptidases; Animals; Brain; Carboxypeptidase H; Carboxypeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Neprilysin; Rats | 1993 |
Hepatic inactivation of Leu-enkephalin.
Topics: Animals; Biliary Tract; Biotransformation; CD13 Antigens; Cell Membrane; Enkephalin, Leucine; Hydrolysis; Iodine Radioisotopes; Leucine; Liver; Male; Mice; Perfusion; Protease Inhibitors; Rats; Rats, Wistar; Succinimides; Tritium; Tyrosine | 1996 |
Characterization of the decline in alcohol consumption by aminopeptidase inhibition.
Topics: Alcohol Drinking; Aminopeptidases; Angiotensin II; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Drinking Behavior; Enkephalins; Imidazoles; Leucine; Losartan; Male; Naltrexone; Rats; Rats, Wistar; Tetrazoles | 1996 |
Differential effect of intestinal neuropeptides on invasion and migration of colon carcinoma cells in vitro.
Topics: Adenocarcinoma; Animals; Biocompatible Materials; Calcitonin Gene-Related Peptide; Cell Division; Cell Movement; Colforsin; Collagen; Colonic Neoplasms; Dideoxyadenosine; Dose-Response Relationship, Drug; Drug Combinations; Enkephalins; Laminin; Leucine; Mice; Neoplasm Invasiveness; Neurokinin A; Neuropeptide Y; Neuropeptides; Proteoglycans; Somatostatin; Substance P; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1997 |
Characterisation of neprilysin (EC 3.4.24.11) S2' subsite.
Topics: Animals; Arginine; Binding Sites; COS Cells; Enkephalins; Gene Expression; Hydrolysis; Kinetics; Leucine; Mutagenesis, Site-Directed; Neprilysin; Substrate Specificity | 1997 |
Rat jejunal permeability and metabolism of mu-selective tetrapeptides in gastrointestinal fluids from humans and rats.
Topics: Amidines; Animals; Drug Stability; Enkephalins; Gastric Juice; Humans; Intestinal Absorption; Jejunum; Leucine; Male; Microvilli; Oligopeptides; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Sulfones; Thiorphan | 1997 |
Enkephalin-processing oligopeptidases in cobra venom: inhibition by thiorphan and bestatin reveals co-operative actions.
Topics: Aminopeptidases; Animals; Drug Synergism; Elapid Venoms; Elapidae; Enkephalins; In Vitro Techniques; Leucine; Peptide Hydrolases; Protease Inhibitors; Substrate Specificity; Thiorphan | 1998 |
The role of aminopeptidase N in Met-enkephalin modulated superoxide anion release.
Topics: Adult; Analgesics; Analgesics, Opioid; CD13 Antigens; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Leucine; Male; Neutrophils; Oligopeptides; Protease Inhibitors; Superoxides | 1999 |
Spectroscopic evidence of beta-turn in N-glycated peptidomimetics related to leucine-enkephalin.
Topics: Enkephalins; Glycopeptides; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Mimicry; Polysaccharides; Protein Conformation; Spectroscopy, Fourier Transform Infrared | 2000 |
Influence of solvents and leucine configuration at position 5 on tryptophan fluorescence in cyclic enkephalin analogues.
Topics: Enkephalins; Fluorescence; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Protein Conformation; Solvents; Spectrometry, Fluorescence; Tryptophan | 2001 |
Fluorescence decay time distribution analysis of cyclic enkephalin analogues; influence of solvent and Leu configuration in position 5 on conformation.
Topics: Enkephalins; Leucine; Models, Chemical; Models, Statistical; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 2001 |
A new water-soluble N-protecting group, 2-(phenyl(methyl)sulfonio)ethyloxycarbonyl tetrafluoroborate, and its application to solid phase peptide synthesis in water.
Topics: Amides; Borates; Boric Acids; Chromatography, High Pressure Liquid; Enkephalins; Indicators and Reagents; Leucine; Models, Chemical; Peptide Biosynthesis; Water | 2001 |
Dual modulation of gabaergic transmission by metabotropic glutamate receptors in rat ventral tegmental area.
Topics: Anesthetics, Local; Animals; Bicuculline; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrophysiology; Enkephalins; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Leucine; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Neural Conduction; Neural Inhibition; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Ventral Tegmental Area | 2003 |
Electrospray mass spectrometric study of anionic complexes of enkephalins with Cu(II): regioselective distinction of Leu/Ile at the C-terminus induced by metal reduction.
Topics: Anions; Copper; Enkephalins; Isoleucine; Leucine; Macromolecular Substances; Metals; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Peptide Fragments; Spectrometry, Mass, Electrospray Ionization | 2003 |
Enkephalins: Raman spectral analysis and comparison as function of pH 1-13.
Topics: Cell Line, Tumor; Circular Dichroism; Enkephalins; Humans; Hydrogen-Ion Concentration; Leucine; Methionine; Models, Chemical; Protein Conformation; Spectrum Analysis, Raman; Tyrosine | 2003 |
Determination of the activation energy for unimolecular dissociation of a non-covalent gas-phase peptide: substrate complex by infrared multiphoton dissociation fourier transform ion cyclotron resonance mass spectrometry.
Topics: Bradykinin; Cyclotrons; Enkephalins; Fourier Analysis; Indicators and Reagents; Infrared Rays; Leucine; Mass Spectrometry; Oligopeptides; Receptors, Peptide | 2003 |
Anionic copper complex fragmentations from enkephalins under low-energy collision-induced dissociation in an ion trap mass spectrometer.
Topics: Anions; Copper; Enkephalins; Glycine; Isoleucine; Leucine; Macromolecular Substances; Peptide Fragments; Spectrometry, Mass, Electrospray Ionization | 2004 |
Establishing low-energy sequential decomposition pathways of leucine enkephalin and its N- and C-terminus fragments using multiple-resonance CID in quadrupolar ion guide.
Topics: Enkephalins; Leucine; Spectrometry, Mass, Electrospray Ionization | 2004 |
Identification of modulating residues defining the catalytic cleft of insulin-regulated aminopeptidase.
Topics: Amino Acid Sequence; Catalytic Domain; Cell Line; Cystinyl Aminopeptidase; Enkephalin, Leucine; Humans; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Recombinant Proteins; Sequence Homology, Amino Acid; Vasopressins | 2008 |
Analysis of samples stored as individual plugs in a capillary by electrospray ionization mass spectrometry.
Topics: Air; Electrophoresis, Capillary; Enkephalins; Leucine; Microfluidic Analytical Techniques; Peptide Fragments; Solvents; Spectrometry, Mass, Electrospray Ionization; Water | 2009 |
Photodissociation of protonated leucine-enkephalin in the VUV range of 8-40 eV.
Topics: Enkephalins; Leucine; Photochemical Processes; Protons; Quantum Theory; Ultraviolet Rays | 2011 |
Pain inhibition by blocking leukocytic and neuronal opioid peptidases in peripheral inflamed tissue.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies; CD13 Antigens; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enzyme Inhibitors; Flow Cytometry; Hindlimb; Inflammation; Leucine; Leukocytes; Male; Narcotic Antagonists; Neprilysin; Neurons; Opioid Peptides; Pain; Pain Threshold; Phosphinic Acids; Rats; Rats, Wistar; Receptors, Opioid; Thiorphan | 2012 |
Nanosolvation-induced stabilization of a protonated peptide dimer isolated in the gas phase.
Topics: Dimerization; Enkephalins; Gases; Leucine; Mass Spectrometry; Molecular Conformation; Peptides; Protons; Quantum Theory; Thermodynamics; Ultraviolet Rays | 2013 |
Spinal ERK2 activation through δ2-opioid receptors contributes to nociceptive behavior induced by intrathecal injection of leucine-enkephalin.
Topics: Animals; Arginine; Behavior, Animal; Butadienes; Enkephalin, Leucine; Enzyme Activation; Glycopeptides; Injections, Spinal; Leucine; Male; Mice, Inbred Strains; Mitogen-Activated Protein Kinase 1; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitriles; Nociception; Protease Inhibitors; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Spinal Cord | 2014 |
Effects of Leucin-Enkephalins on Surface Characteristics and Morphology of Model Membranes Composed of Raft-Forming Lipids.
Topics: Enkephalins; Leucine; Membrane Lipids; Membrane Microdomains; Surface Tension | 2016 |
VUV action spectroscopy of protonated leucine-enkephalin peptide in the 6-14 eV range.
Topics: Enkephalins; Leucine; Peptides; Photolysis; Protons; Spectrophotometry, Ultraviolet; Ultraviolet Rays | 2015 |
Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala.
Topics: Amygdala; Animals; Captopril; Electrical Synapses; Enkephalins; Glutamic Acid; Leucine; Male; Neprilysin; Protease Inhibitors; Proteolysis; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiorphan | 2020 |
Collision Cross-Section Measurements of Collision-Induced Dissociation Precursor and Product Ions in an FTICR-MS and an IM-MS: A Comparative Study.
Topics: Crown Ethers; Enkephalin, Leucine; Ions; Leucine; Mass Spectrometry | 2022 |
The opioid peptide leucine-enkephalin disrupts seasonal and gonadotropin-induced ovarian recrudescence in the gecko Hemidactylus frenatus.
Topics: Animals; Enkephalin, Leucine; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Leucine; Lizards; Opioid Peptides; Ovarian Follicle; Ovary; Seasons | 2023 |