enkephalin, leucine and leucine

enkephalin, leucine has been researched along with leucine in 111 studies

Research

Studies (111)

TimeframeStudies, this research(%)All Research%
pre-199068 (61.26)18.7374
1990's22 (19.82)18.2507
2000's12 (10.81)29.6817
2010's6 (5.41)24.3611
2020's3 (2.70)2.80

Authors

AuthorsStudies
Dray, F; Gros, C; Lafon-Cazal, M1
Frenk, H; Liebeskind, JC; Urca, G1
Aliautdin, RN; Chichenkov, ON; Fisenko, VP1
Huidobro, F; Huidobro-Toro, JP; Miranda, H1
Childers, S; Larsson, LI; Snyder, SH1
Dolganov, GM; Efimov, VA; Monastyrskaia, GS; Ovchinnikov, IuA; Sverdlov, ED1
Chichenkov, ON; Fisenko, VP; Novikov, NN1
Di Giulio, AM; Majane, EM; Yang, HY1
Frederickson, RC; Richter, JA; Wesche, DL1
Guarneri, M; Salvadori, S; Tomatis, R1
Bhargava, HN1
Kosterlitz, HW; Leslie, FM; Ling, N; Lord, JA; Waterfield, AA1
Kullmann, W1
Davis, WG; Delaney, PV; Tormey, WP1
Dray, F; Gros, C; Humbert, J; Pradelles, P1
Hughes, J; Kosterlitz, HW; McKnight, AT; Sosa, RP1
Hughes, J; Kosterlitz, HW; Smith, TW1
Costa, E; Hong, JS; Yang, HY1
Salvadori, S; Tomatis, R1
Bawab, W; Crine, P; DesGroseillers, L; Querido, E1
Aungst, BJ; Hussain, MA1
Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mantelet, S1
Goodman, M; Said-Nejad, OE; Schiller, PW; Yamazaki, T1
Baas, AA; Dzoljic, MM; Dzoljic, MR; Rupreht, J; Ukponmwan, OE; van den Berg, DJ1
Ishikawa, K; Martinez, JL; Shibanoki, S; Weinberger, SB1
Ayala, JM; Molineaux, CJ1
Costentin, J; Dourmap, N; Michael-Titus, A; Schwartz, JC1
Beniston, D; Bennett, EL; Ishikawa, K; Martinez, JL; Nudelman, KA; Rosenzweig, MR; Schulteis, G; Shibanoki, S; Weinberger, SB1
Beliaev, NA; Kelesheva, LF; Kolesanova, EF; Panchenko, LF; Rotanova, TV1
Giros, B; Llorens-Cortes, C; Quach, TT; Schwartz, JC; Van Amsterdam, JG1
Herz, A; Parsons, CG1
Gerothanassis, IP; Karayannis, T; Marraud, M; Sakarellos, C; Sakarellos-Daitsiotis, M1
Aungst, BJ; Hussain, MA; Koval, CA; Shenvi, AB1
Caline, H; Costentin, J; Dourmap, N; Michael-Titus, A; Schwartz, JC1
Livett, BG; Marley, PD; Mitchelhill, KI1
Martinez, JL; Weinberger, SB1
Altiere, RJ; Crooks, PA; Gillespie, MN; Krechniak, JW; Olson, JW1
Giros, B; Gros, C; Llorens-Cortes, C; Schwartz, JC1
Barchas, JD; Evans, CJ; Hurlbut, DE; Leslie, FM1
Bausback, HH; Churchill, L; Palmieri, FE; Ward, PE1
Martinez, JL; Walker, RC; Weinberger, SB; Zafuto, CE1
Gros, C; Llorens-Cortes, C; Schwartz, JC2
Hammonds, RG; Li, CH; Westphal, M1
Kameyama, T; Katoh, A; Nabeshima, T1
Dzoljić, E; Varagić, VM1
Dickenson, AH; Fournie-Zaluski, MC; Roques, BP; Sullivan, AF1
Carson, LW; Kashi, SD; Lee, VH; Stratford, RE1
Audus, KL; Baranczyk-Kuzma, A1
Bouboutou, R; Bourgoin, S; Cesselin, F; Devin, J; Fournie-Zaluski, MC; Hamon, M; Roques, B; Waksman, G1
Han, JS; Yuan, H1
Han, JS; Jin, WQ; Zhou, ZF1
Bailey, C; Kitchen, I1
Iwama, T; Satoh, M; Takagi, H; Wada, T1
Ishida, J; Kai, M; Ohkura, Y1
Chaillet, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Zajac, JM1
Aoki, K; Kajiwara, M; Oka, T1
Herkenham, M; Pert, CB1
Basbaum, AI; Moss, MS1
Bakalkin, GIa; Iarygin, KN; Smirnov, VN; Titov, MI; Trushina, ED1
Bui, ND; Deschodt-Lanckman, M1
Corbett, AD; Kosterlitz, HW; McKnight, AT1
Chaillet, P; Costentin, J; de la Baume, S; Marcais-Collado, H; Schwartz, JC; Yi, CC3
Chaillet, P; Costentin, J; Coulaud, A; Fournié-Zaluski, MC; Gacel, G; Roques, BP1
Brandt, U; Lentzen, H; Palenker, J1
Lentzen, H; Palenker, J1
Geary, LE; Kerchner, GA1
Carenzi, A; Della Bella, D; Frigeni, V; Reggiani, A1
Bouboutou, R; Chaillet, P; Cherot, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Waksman, G1
Chaillet, P; Costentin, J; Lecomte, JM; Marçais, H; Natan, LB; Uchida, G1
Llorens-Cortes, C; Schwartz, JC1
Davis, KR; Hernandez, DE; Wolfenden, R1
Costa, E; Yang, HY; Zhang, AZ1
Cohen, ML; Geary, LE; Wiley, KS1
Hazato, T; Kasama, A; Katayama, T; Kaya, K; Nishioka, S; Shimamura, M1
Bulgakov, SA; Polonskiĭ, VM; Shatalov, VN; Smagin, VG; Vinogradov, VA1
Jeffcoate, WJ1
Hazato, T; Inagaki-Shimamura, M; Katayama, T; Yamamoto, T1
Barbeau, A; Izumi, K; Munekata, E; Nakanishi, T; Wong, P; Yamamoto, H; Yoshida, M1
Barbeau, A; Izumi, K; Munekata, E; Nakanishi, T; Yamamoto, H1
Baronets, VIu; Beliaev, NA; Kolesanova, EF; Panchenko, LF1
Billington, D; MacKinnon, KL; Zuzel, KA1
Grupp, LA; Harding, S; Szczepanska, R1
Ayukawa, K; Murata, J; Ogasawara, M; Saimi, I1
Boileau, G; Cohen, P; Crine, P; Dion, N1
Ekström, G; Krondahl, E; Lennernäs, H; Orzechowski, A1
Anderson, L; Bussler, B; Dufton, M; Martins, H1
Abramić, M; Balog, T; Hrsak, I; Marotti, T; Svoboda-Beusen, I1
Cudić, MB; Hollósi, M; Horvat, S; Kojić-Prodić, B; Kveder, M; Vass, E1
Czaplewski, C; Groth, M; Karolczak, J; Liwo, A; Malicka, J; Wiczk, W1
Czaplewski, C; Ganzynkowicz, R; Groth, M; Karolczak, J; Liwo, A; Malicka, J; Wiczk, W1
Hojo, K; Kawasaki, K; Maeda, M1
Johnson, SW; Zheng, F1
Bellier, B; Bossée, A; Fournier, F; Tabet, JC; Tasseau, O1
Abdali, S; Bohr, H; Nielsen, OF; Refstrup, P1
Chalmers, MJ; Cooper, HJ; Heil, M; Hendrickson, CL; Marshall, AG; Schäfer, M; Schmuck, C1
Afonso, C; Bellier, B; Bossée, A; Fournier, F; Pepe, C; Tabet, JC; Tasseau, O1
Borisov, OV; Rakov, VS; Whitehouse, CM1
Albiston, AL; Ascher, DB; Chai, SY; Lew, RA; Morton, CJ; Parker, MW; Ye, S1
Kennedy, RT; Lee, MS; Li, Q; Pei, J; Valaskovic, GA1
Bari, S; Gonzalez-Magaña, O; Hoekstra, R; Reitsma, G; Schippers, S; Schlathölter, T; Werner, J1
Fournie-Zaluski, MC; Gore, C; Labuz, D; Machelska, H; Roques, BP; Schreiter, A; Stein, C1
Canon, F; Cerovski, VZ; Giuliani, A; Milosavljević, AR; Nahon, L1
Katsuyama, S; Komatsu, T; Mizoguchi, H; Sakurada, C; Sakurada, S; Sakurada, T; Tsuzuki, M1
Jordanova, A; Lalchev, Z; Tsanova, A1
Canon, F; Giuliani, A; Milosavljević, AR; Nahon, L; Ranković, MLj1
Bagley, EE; Gregoriou, GC; Patel, SD; Winters, BL1
Arslanian, AJ; Dearden, DV; Mismash, N1
Ganesh, CB; Ganeyan, A1

Reviews

1 review(s) available for enkephalin, leucine and leucine

ArticleYear
Brain peptides and pain sensation.
    American heart journal, 1980, Volume: 99, Issue:1

    Topics: Animals; beta-Lipotropin; Brain Chemistry; Endorphins; Enkephalins; Fluorescent Antibody Technique; Guinea Pigs; Humans; Leucine; Methionine; Mice; Morphine; Narcotics; Pain; Peptides; Radioimmunoassay; Rats

1980

Other Studies

110 other study(ies) available for enkephalin, leucine and leucine

ArticleYear
[Presence of substances immunoreactively related to enkephalin in an insect, Locusta migratoria].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1978, Sep-25, Volume: 287, Issue:6

    Topics: Animals; Chromatography, Gel; Endorphins; Enkephalins; Female; Grasshoppers; Leucine; Male; Methionine; Molecular Weight; Nervous System; Radioimmunoassay; Tissue Distribution

1978
Epileptic properties of leucine- and methionine-enkephalin: comparison with morphine and reversibility by naloxone.
    Brain research, 1978, May-26, Volume: 147, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Electroencephalography; Endorphins; Enkephalins; Injections, Intraventricular; Leucine; Male; Methionine; Morphine; Naloxone; Rats; Receptors, Opioid; Seizures

1978
[Effect of leucine-enkephalin on the interneuronal transmission of excitation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1979, Volume: 87, Issue:6

    Topics: Animals; Cats; Central Nervous System; Drug Interactions; Electric Stimulation; Endorphins; Enkephalins; Evoked Potentials; Female; Leucine; Male; Methysergide; Naloxone; Synaptic Transmission

1979
Evidence for morphine and morphine-like alkaloid responses resistant to naloxone blockade in the rat vas deferens.
    Life sciences, 1979, Apr-16, Volume: 24, Issue:16

    Topics: Animals; Drug Tolerance; Electric Stimulation; Enkephalins; In Vitro Techniques; Leucine; Male; Morphine; Morphine Derivatives; Muscle Contraction; Naloxone; Narcotics; Placebos; Rats; Receptors, Opioid; Vas Deferens

1979
Met- and Leu-enkephalin immunoreactivity in separate neurones.
    Nature, 1979, Nov-22, Volume: 282, Issue:5737

    Topics: Amino Acid Sequence; Animals; Antibody Specificity; Brain; Cats; Endorphins; Enkephalins; Immunologic Techniques; Intestine, Small; Leucine; Methionine; Models, Biological; Myenteric Plexus

1979
[Synthesis of the leucine-enkephalin gene, its cloning and expression in Escherichia coli].
    Doklady Akademii nauk SSSR, 1979, Volume: 248, Issue:6

    Topics: Base Sequence; Cloning, Molecular; DNA, Recombinant; Endorphins; Enkephalins; Escherichia coli; Genes; Genetic Engineering; Genetic Vectors; Leucine; Plasmids

1979
[Effect of leucine-enkephalin on the neuronal activity of the cerebral cortex].
    Biulleten' eksperimental'noi biologii i meditsiny, 1979, Volume: 88, Issue:7

    Topics: Action Potentials; Animals; Cerebral Cortex; Endorphins; Enkephalins; Leucine; Neural Inhibition; Neurons; Rats; Somatosensory Cortex; Time Factors

1979
On the distribution of [met5]- and [leu5]-enkephalins in the brain of the rat, guinea-pig and calf.
    British journal of pharmacology, 1979, Volume: 66, Issue:2

    Topics: Animals; Brain Chemistry; Cattle; Cerebral Cortex; Corpus Striatum; Endorphins; Enkephalins; Guinea Pigs; Hippocampus; Hypothalamus; Leucine; Male; Methionine; Radioimmunoassay; Rats; Species Specificity; Tissue Distribution

1979
K-stimulated release of leu- and met-enkephalin from rat striatal slices: lack of effect of morphine and naloxone.
    European journal of pharmacology, 1979, Volume: 56, Issue:1-2

    Topics: Animals; Calcium; Corpus Striatum; Endorphins; Enkephalins; In Vitro Techniques; Leucine; Magnesium; Male; Methionine; Morphine; Naloxone; Potassium; Radioimmunoassay; Rats

1979
Use of iminodiacetic acid for the synthesis of piperazinyl peptides related to leu-enkephalin. II.
    Il Farmaco; edizione scientifica, 1979, Volume: 34, Issue:8

    Topics: Animals; Endorphins; Enkephalins; Glycine; Guinea Pigs; Ileum; Imino Acids; Leucine; Male; Mice; Peptides; Piperazines; Vas Deferens

1979
Studies of the possible role of brain endorphins in pentobarbital anesthesia and toxicity in mice.
    Anesthesiology, 1979, Volume: 51, Issue:5

    Topics: Animals; Brain; Endorphins; Enkephalins; Leucine; Male; Mice; Morphine; Naloxone; Naltrexone; Pentobarbital; Phenylalanine

1979
Opioid activities of fragments of beta-endorphin and of its leucine65-analogue. Comparison of the binding properties of methionine- and leucine-enkephalin.
    European journal of pharmacology, 1979, Sep-01, Volume: 58, Issue:1

    Topics: Animals; beta-Lipotropin; Brain; Brain Chemistry; Endorphins; Enkephalins; Guinea Pigs; In Vitro Techniques; Leucine; Ligands; Methionine; Mice; Muscle Contraction; Swine

1979
Enzymatic synthesis of Leu- and Met-enkephalin.
    Biochemical and biophysical research communications, 1979, Nov-28, Volume: 91, Issue:2

    Topics: Amino Acids; Chymotrypsin; Endorphins; Enkephalins; Leucine; Methionine; Methods; Papain

1979
Enkephalins in large bowel malignancy and in acute appendicitis.
    Gut, 1979, Volume: 20, Issue:10

    Topics: Acute Disease; Adenocarcinoma; Appendicitis; Appendix; Cecal Neoplasms; Colon; Colonic Neoplasms; Endorphins; Enkephalins; Humans; Leucine; Methionine

1979
Enkephalin-like products in embryonic chicken retina.
    Neuroscience letters, 1979, Volume: 12, Issue:2-3

    Topics: Animals; Chick Embryo; Chromatography, High Pressure Liquid; Endorphins; Enkephalins; Leucine; Methionine; Radioimmunoassay; Retina

1979
Incorporation of labelled amino acids into the enkephalins.
    FEBS letters, 1977, Dec-01, Volume: 84, Issue:1

    Topics: Animals; Brain; Cycloheximide; Endorphins; Enkephalins; Leucine; Male; Methionine; Myenteric Plexus; Protein Precursors; Puromycin; Rats; Tyrosine

1977
The distribution of methionine-enkephalin and leucine-enkephalin in the brain and peripheral tissues.
    British journal of pharmacology, 1977, Volume: 61, Issue:4

    Topics: Animals; Brain Chemistry; Corpus Striatum; Endorphins; Enkephalins; Guinea Pigs; Hypothalamus; Ileum; Leucine; Methionine; Methods; Mice; Peptides; Pituitary Gland; Rabbits; Rats; Tissue Distribution

1977
Regional distribution of LEU and MET enkephalin in rat brain.
    Neuropharmacology, 1977, Volume: 16, Issue:4

    Topics: Animals; Brain Chemistry; Cerebellum; Cerebral Cortex; Corpus Striatum; Enkephalins; Hippocampus; Hypothalamus; Leucine; Medulla Oblongata; Mesencephalon; Methionine; Oligopeptides; Rats

1977
N-terminal Leu-enkephalin rearrangements.
    Il Farmaco; edizione scientifica, 1977, Volume: 32, Issue:8

    Topics: Chemical Phenomena; Chemistry; Electrophoresis, Paper; Enkephalins; Hydrolysis; Leucine; Oligopeptides; Peptide Chain Termination, Translational

1977
Identification and characterization of aminopeptidases from Aplysia californica.
    The Biochemical journal, 1992, Sep-15, Volume: 286 ( Pt 3)

    Topics: Aminopeptidases; Anilides; Aniline Compounds; Animals; Anti-Bacterial Agents; Aplysia; Bacitracin; Chromatography, High Pressure Liquid; Enkephalin, Leucine; FMRFamide; Ganglia; Hemolymph; Kidney; Leucine; Male; Myocardium; Neuropeptides; Oligopeptides; Oviducts; Peptides; Puromycin; Testis

1992
Nasal absorption of leucine enkephalin in rats and the effects of aminopeptidase inhibition, as determined from the percentage of the dose unabsorbed.
    Pharmaceutical research, 1992, Volume: 9, Issue:10

    Topics: Absorption; Amino Acid Sequence; Aminopeptidases; Animals; Boron Compounds; Enkephalin, Leucine; Half-Life; Leucine; Male; Molecular Sequence Data; Nasal Mucosa; Protease Inhibitors; Rats

1992
Feedback inhibition of met-enkephalin release from the rat spinal cord in vivo.
    Synapse (New York, N.Y.), 1992, Volume: 11, Issue:1

    Topics: Animals; Calcitonin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Feedback; Indoles; Injections, Spinal; Leucine; Male; Morphinans; Naloxone; Naltrexone; Oligopeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan

1992
Conformational studies of stereoisomeric 14-membered cyclic enkephalin analogues containing 1-naphthylalanine at the fourth position: chirality effect of leucine at the fifth position on biological activity and receptor selectivity.
    Biopolymers, 1991, Volume: 31, Issue:7

    Topics: Alanine; Amino Acid Sequence; Enkephalins; Leucine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Conformation; Receptors, Opioid; Spectrum Analysis; Structure-Activity Relationship; Temperature

1991
Suppressive effects of enkephalins and REM sleep deprivation on seizures.
    Epilepsy research. Supplement, 1991, Volume: 2

    Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Electroshock; Enkephalins; Glycopeptides; Leucine; Male; Mice; Mice, Inbred Strains; Neprilysin; Nitrous Oxide; Rats; Rats, Inbred Strains; Sleep Deprivation; Sleep, REM; Substance Withdrawal Syndrome; Thiorphan

1991
HPLC-ECD determination of the enzymatic hydrolysis of [leu]- and [met]enkephalin in rat plasma.
    Progress in clinical and biological research, 1990, Volume: 328

    Topics: Acetylcholinesterase; Aminopeptidases; Animals; Captopril; CD13 Antigens; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Hydrolysis; In Vitro Techniques; Leucine; Male; Oligopeptides; Rats; Rats, Inbred Strains; Thiorphan; Tyrosine

1990
An inhibitor of endopeptidase-24.15 blocks the degradation of intraventricularly administered dynorphins.
    Journal of neurochemistry, 1990, Volume: 55, Issue:2

    Topics: Animals; Brain; Captopril; Cerebral Ventricles; Choroid Plexus; Dynorphins; Enkephalin, Leucine; Kinetics; Leucine; Male; Metalloendopeptidases; Neprilysin; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains

1990
Role of delta opioid receptors in the effects of inhibitors of enkephalin-degrading peptidases on the horizontal and vertical components of locomotion in mice.
    Neuropeptides, 1990, Volume: 15, Issue:2

    Topics: Aminopeptidases; Animals; CD13 Antigens; Dipeptides; Drug Synergism; Enkephalin, Leucine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Leucine; Locomotion; Male; Mice; Naloxone; Neprilysin; Phenylcarbamates; Prodrugs; Receptors, Opioid; Receptors, Opioid, delta; Sulfhydryl Compounds; Thiorphan

1990
Hydrolysis of [Leu]enkephalin by chick plasma in vitro.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:2

    Topics: Aminopeptidases; Animals; Chickens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Enkephalin, Leucine; Hydrolysis; In Vitro Techniques; Leucine; Male; Puromycin

1991
[The effect of the aminopeptidase inhibitor bestatin on the enkephalin level in the rat brain].
    Biulleten' eksperimental'noi biologii i meditsiny, 1990, Volume: 110, Issue:11

    Topics: Aminopeptidases; Animals; Brain; Brain Chemistry; Dimethyl Sulfoxide; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Leucine; Male; Rats

1990
Enkephalin biosynthesis and release in mouse striatum are inhibited by GABA receptor stimulation: compared changes in preproenkephalin mRNA and Tyr-Gly-Gly levels.
    Brain research. Molecular brain research, 1990, Volume: 8, Issue:3

    Topics: Aminooxyacetic Acid; Animals; Corpus Striatum; Diazepam; Enkephalins; Flumazenil; Kinetics; Leucine; Male; Mice; Muscimol; Oligopeptides; Protein Precursors; Receptors, GABA-A; RNA, Messenger

1990
Peripheral opioid receptors mediating antinociception in inflammation. Evidence for activation by enkephalin-like opioid peptides after cold water swim stress.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Analgesia; Animals; Dioxolanes; Dipeptides; Enkephalins; Inflammation; Leucine; Male; Naloxone; Naltrexone; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological; Swimming; Thiorphan

1990
17O- and 14N-NMR studies of Leu-enkephalin and enkephalin-related fragments in aqueous solution.
    Biopolymers, 1990, Feb-05, Volume: 29, Issue:2

    Topics: Amino Acid Sequence; Enkephalin, Leucine; Hydrogen-Ion Concentration; Leucine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Weight; Nitrogen Isotopes; Oxygen Isotopes; Peptide Fragments; Protein Conformation; Solutions; Thermodynamics; Water

1990
Recovery of rat nasal mucosa from the effects of aminopeptidase inhibitors.
    Journal of pharmaceutical sciences, 1990, Volume: 79, Issue:5

    Topics: Aminopeptidases; Animals; Boron; Boron Compounds; Enkephalin, Leucine; Leucine; Nasal Mucosa; Puromycin; Rats

1990
Role of endogenous enkephalins in locomotion and nociception studied with peptidase inhibitors in two inbred strains of mice (C57BL/6J and DBA/2J).
    Neuropharmacology, 1989, Volume: 28, Issue:2

    Topics: Analgesics; Animals; Cerebral Ventricles; Enkephalins; Injections, Intraventricular; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Naloxone; Pain; Protease Inhibitors; Reference Values; Species Specificity; Thiorphan

1989
Effects of opioid peptides containing the sequence of Met5-enkephalin or Leu5-enkephalin on nicotine-induced secretion from bovine adrenal chromaffin cells.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: Adenosine Triphosphate; Adrenal Medulla; Amino Acid Sequence; Animals; Bacitracin; Cattle; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Epinephrine; Guinea Pigs; Leucine; Nicotine; Norepinephrine; Peptide Fragments; Phenanthrolines; Rabbits; Receptors, Opioid; Thiorphan; Tiopronin

1986
Characterization of hydrolysis of [leu]enkephalin and D-ala2-[L-leu]enkephalin in rat plasma.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: Aminopeptidases; Animals; CD13 Antigens; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Half-Life; Hydrolysis; Leucine; Male; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Thiorphan

1988
Pulmonary metabolism of exogenous enkephalins in isolated perfused rat lungs.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3

    Topics: Aminopeptidases; Animals; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; In Vitro Techniques; Leucine; Lung; Male; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains; Tyrosine

1985
[Opioid peptides: metabolism and receptors].
    Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:3 Pt 2

    Topics: Animals; Brain; Cattle; Endopeptidases; Endorphins; Enkephalins; Humans; Leucine; Mice; Neprilysin; Pro-Opiomelanocortin; Protease Inhibitors; Protein Precursors; Receptors, Opioid; Thiorphan; Tiopronin

1987
Pharmacological properties of a proenkephalin A-derived opioid peptide: BAM 18.
    European journal of pharmacology, 1987, Jun-26, Volume: 138, Issue:3

    Topics: Animals; Biological Assay; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; In Vitro Techniques; Leucine; Male; Naloxone; Protein Precursors; Radioligand Assay; Receptors, Opioid; Structure-Activity Relationship

1987
Kinin and enkephalin conversion by an endothelial, plasma membrane carboxypeptidase.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: 3-Mercaptopropionic Acid; Animals; Carboxypeptidases; Cell Membrane; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Edetic Acid; Endothelium; Enkephalins; Glycopeptides; Hydrogen-Ion Concentration; Kinetics; Kinins; Leucine; Lysine Carboxypeptidase; Microscopy, Phase-Contrast; Muscle, Smooth, Vascular; Phenanthrolines; Puromycin; Swine

1986
Characterization of enkephalin degradation in rat plasma.
    NIDA research monograph, 1986, Volume: 75

    Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Leucine; Enkephalins; Kinetics; Leucine; Male; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin

1986
Evaluation of striatal enkephalin release in vivo from steady state levels and turnover rates of the tripeptide Tyr-Gly-Gly.
    NIDA research monograph, 1986, Volume: 75

    Topics: Animals; Anti-Bacterial Agents; Corpus Striatum; Enkephalins; In Vitro Techniques; Kinetics; Leucine; Male; Mice; Oligopeptides; Pentobarbital; Thiorphan; Tiopronin

1986
Protease inhibition increases the analgesic potency of peptide E.
    Neuropharmacology, 1985, Volume: 24, Issue:2

    Topics: Analgesics; Animals; Bacitracin; beta-Endorphin; Drug Synergism; Endorphins; Enkephalins; Injections, Intraventricular; Leucine; Male; Mice; Peptides; Protease Inhibitors

1985
Inhibition of enkephalin degradation attenuated stress-induced motor suppression (conditioned suppression of motility).
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:1

    Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Enkephalins; Leucine; Male; Metalloendopeptidases; Mice; Motor Activity; Naloxone; Neprilysin; Pimozide; Stress, Physiological; Thiorphan; Tiopronin

1988
Effects of bestatin and phosphoramidon on the hypertensive response to physostigmine in the rat.
    Fundamental & clinical pharmacology, 1987, Volume: 1, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Blood Pressure; Carotid Arteries; Catecholamines; Enkephalin, Leucine; Female; Glycopeptides; Injections, Intra-Arterial; Leucine; Male; Naloxone; Physostigmine; Rats; Rats, Inbred Strains

1987
Prevention of degradation of endogenous enkephalins produces inhibition of nociceptive neurones in rat spinal cord.
    Brain research, 1987, Apr-07, Volume: 408, Issue:1-2

    Topics: Action Potentials; Animals; Dipeptides; Enkephalins; Leucine; Male; Naloxone; Nerve Fibers; Neural Inhibition; Neurons, Afferent; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Tiopronin

1987
Metabolic and permeation barriers to the ocular absorption of topically applied enkephalins in albino rabbits.
    Journal of ocular pharmacology, 1986,Fall, Volume: 2, Issue:4

    Topics: Absorption; Administration, Topical; Animals; Enkephalins; Eye; Leucine; Male; Permeability; Rabbits

1986
Characteristics of aminopeptidase activity from bovine brain microvessel endothelium.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1987, Volume: 7, Issue:6

    Topics: Aminopeptidases; Animals; Blood-Brain Barrier; Brain; Cattle; Cell Membrane; Cells, Cultured; Endothelium, Vascular; Enkephalins; Kidney; Leucine; Neuropeptides; Puromycin

1987
In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain.
    European journal of pharmacology, 1985, Nov-05, Volume: 117, Issue:2

    Topics: Aminopeptidases; Animals; Brain; Brain Chemistry; Corpus Striatum; Dipeptides; Enkephalin, Methionine; Enkephalins; Hydrolysis; In Vitro Techniques; Leucine; Mice; Protease Inhibitors; Rats; Thiorphan; Tiopronin

1985
[Electroacupuncture accelerates the biogenesis of central enkephalins in the rat].
    Sheng li xue bao : [Acta physiologica Sinica], 1985, Volume: 37, Issue:3

    Topics: Acupuncture Therapy; Aminopeptidases; Animals; Brain; Electric Stimulation Therapy; Enkephalin, Leucine; Enkephalin, Methionine; Female; Leucine; Male; Phenylalanine; Radioimmunoassay; Rats; Thiorphan; Tiopronin; Transcutaneous Electric Nerve Stimulation

1985
Study of endogenous Tyr-Gly-Gly, a putative enkephalin metabolite, in mouse brain: validation of a radioimmunoassay, localisation and effects of peptidase inhibitors.
    European journal of pharmacology, 1985, Dec-17, Volume: 119, Issue:3

    Topics: Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Mice; Microwaves; Nalorphine; Neprilysin; Oligopeptides; Protease Inhibitors; Radioimmunoassay; Thiorphan; Tiopronin

1985
[Inhibition of enkephalins degradation in the nucleus accumbens leads to potentiation of acupuncture and morphine analgesia].
    Sheng li xue bao : [Acta physiologica Sinica], 1985, Volume: 37, Issue:4

    Topics: Acupuncture Therapy; Aminopeptidases; Analgesia; Animals; Electric Stimulation Therapy; Endopeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Morphine; Neprilysin; Nucleus Accumbens; Protease Inhibitors; Rabbits; Septal Nuclei; Thiorphan; Tiopronin; Transcutaneous Electric Nerve Stimulation

1985
Determination of proenkephalin products in brain tissue by high-performance liquid chromatography and a modified bioassay procedure.
    Journal of pharmacological methods, 1985, Volume: 13, Issue:3

    Topics: Animals; Biological Assay; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Electric Stimulation; Endorphins; Enkephalins; In Vitro Techniques; Leucine; Male; Mice; Muscle Contraction; Muscle, Smooth; Protein Precursors

1985
Sites of analgesic actions of kyotorphin and D-kyotorphin in the central nervous system of rats.
    Neuropeptides, 1985, Volume: 5, Issue:4-6

    Topics: Analgesics; Animals; Central Nervous System; Endorphins; Enkephalins; Leucine; Male; Naloxone; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reticular Formation; Spinal Cord

1985
Determination of p-hydroxybestatin in human serum by high-performance liquid chromatography using fluorescence detection.
    Journal of chromatography, 1985, Nov-08, Volume: 344

    Topics: Chemical Phenomena; Chemistry; Child; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Leucine; Muscular Dystrophies; Spectrometry, Fluorescence; Temperature

1985
The mu rather than the delta subtype of opioid receptors appears to be involved in enkephalin-induced analgesia.
    European journal of pharmacology, 1984, May-18, Volume: 101, Issue:1-2

    Topics: Analgesics; Animals; Enkephalin, Leucine; Enkephalins; Guinea Pigs; In Vitro Techniques; Leucine; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Nalorphine; Naloxone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thiorphan; Tiopronin

1984
The role of bestatin-sensitive aminopeptidase, angiotensin converting enzyme and thiorphan-sensitive "enkephalinase" in the potency of enkephalins in the guinea-pig ileum.
    Japanese journal of pharmacology, 1984, Volume: 36, Issue:1

    Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin

1984
Mosaic distribution of opiate receptors, parafascicular projections and acetylcholinesterase in rat striatum.
    Nature, 1981, Jun-04, Volume: 291, Issue:5814

    Topics: Acetylcholinesterase; Animals; Axonal Transport; Caudate Nucleus; Corpus Striatum; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Leucine; Naloxone; Proline; Rats; Receptors, Opioid

1981
The peptidergic organization of the cat periaqueductal gray. II. The distribution of immunoreactive substance P and vasoactive intestinal polypeptide.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1983, Volume: 3, Issue:7

    Topics: Animals; Cats; Enkephalins; Gastrointestinal Hormones; Leucine; Periaqueductal Gray; Substance P; Vasoactive Intestinal Peptide

1983
[Preferential development of flexion of the left or right hindlimb as a result of treatment with methionine-enkephalin or leucine-enkephalin, respectively].
    Doklady Akademii nauk SSSR, 1980, Volume: 252, Issue:3

    Topics: Animals; Dominance, Cerebral; Endorphins; Enkephalins; Hindlimb; Leucine; Methionine; Naloxone; Posture; Rats; Receptors, Opioid; Structure-Activity Relationship

1980
Cholecystokinin octa- and tetrapeptide degradation by synaptic membranes. I. Evidence for competition with enkephalins for in vitro common degradation pathways.
    Peptides, 1981, Volume: 2 Suppl 2

    Topics: Aminopeptidases; Animals; Cholecystokinin; Chromatography, DEAE-Cellulose; Endorphins; Enkephalin, Leucine; Enkephalins; Gastrins; Kinetics; Leucine; Male; Peptide Fragments; Rats; Sincalide; Synaptic Membranes; Tetragastrin; Tryptophan

1981
Increase in potencies of opioid peptides after peptidase inhibition.
    European journal of pharmacology, 1983, Jan-21, Volume: 86, Issue:3-4

    Topics: Animals; beta-Endorphin; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Leucine; Male; Mice; Myenteric Plexus; Protease Inhibitors; Rats; Rats, Inbred Strains; Vas Deferens

1983
Participation of both 'enkephalinase' and aminopeptidase activities in the metabolism of endogenous enkephalins.
    Neuroscience, 1983, Volume: 8, Issue:1

    Topics: Aminopeptidases; Animals; Corpus Striatum; Endopeptidases; Enkephalins; Leucine; Male; Neprilysin; Nociceptors; Rats; Rats, Inbred Strains; Sensory Thresholds; Synaptic Transmission

1983
Pain control by endogenous enkephalins is mediated by mu opioid receptors.
    Life sciences, 1983, Volume: 33 Suppl 1

    Topics: Amino Acids, Sulfur; Analgesia; Animals; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Pain; Protease Inhibitors; Receptors, Opioid; Receptors, Opioid, mu; Thiorphan; Tiopronin

1983
Enkephalin degradation by enkephalinergic neuroblastoma cells. Involvement of angiotensin-converting-enzyme.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 325, Issue:3

    Topics: Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Cell Membrane; Cells, Cultured; Enkephalin, Leucine; Hydrolysis; Leucine; Mice; Neuroblastoma; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin

1984
Localization of the thiorphan-sensitive endopeptidase, termed enkephalinase A, on glial cells.
    FEBS letters, 1983, Mar-07, Volume: 153, Issue:1

    Topics: Aminopeptidases; Animals; Astrocytes; Brain; Cell Membrane; Cells, Cultured; Endopeptidases; Enkephalin, Leucine; Kinetics; Leucine; Neprilysin; Protease Inhibitors; Rats; Thiorphan; Tiopronin

1983
Studies on the transport of enkephalin-like oligopeptides in rat intestinal mucosa.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Aminopeptidases; Animals; Biological Transport, Active; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Male; Oligopeptides; Puromycin; Rats; Rats, Inbred Strains; Tyrosine

1983
Peptidases involved in the inactivation of exogenous and endogenous enkephalins.
    Journal of neural transmission. Supplementum, 1983, Volume: 18

    Topics: Aminopeptidases; Animals; Brain; Endopeptidases; Enkephalins; Leucine; Mice; Neprilysin; Nociceptors; Rats; Thiorphan; Tiopronin

1983
Effect of inhibition of neuropeptidases on the pain threshold of mice and rats.
    Neuropharmacology, 1983, Volume: 22, Issue:11

    Topics: Aminopeptidases; Animals; Endopeptidases; Enkephalin, Leucine; Leucine; Male; Mice; Neprilysin; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Sensory Thresholds; Species Specificity; Thiorphan; Tiopronin

1983
Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes.
    European journal of pharmacology, 1984, Jul-20, Volume: 102, Issue:3-4

    Topics: Aminopeptidases; Analgesics; Animals; Brain; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kidney; Leucine; Neprilysin; Protease Inhibitors; Rabbits; Rats; Reaction Time; Thiorphan; Tiopronin

1984
Inhibition of enkephalin metabolism by, and antinociceptive activity of, bestatin, an aminopeptidase inhibitor.
    European journal of pharmacology, 1983, Jan-21, Volume: 86, Issue:3-4

    Topics: Aminopeptidases; Analgesics; Animals; Brain; Drug Synergism; Enkephalins; Hydrolysis; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred Strains; Puromycin; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin

1983
Involvement of endogenous enkephalins in the mouse 'behavioral despair' test.
    European journal of pharmacology, 1984, Jan-27, Volume: 97, Issue:3-4

    Topics: Aminopeptidases; Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Motor Activity; Naloxone; Protease Inhibitors; Thiorphan; Tiopronin

1984
Changes in turnover of cerebral monoamines following inhibition of enkephalin metabolism by thiorphan and bestatin.
    European journal of pharmacology, 1984, Sep-17, Volume: 104, Issue:3-4

    Topics: alpha-Methyltyrosine; Amino Acids, Sulfur; Aminopeptidases; Animals; Biogenic Amines; Brain; Enkephalins; Leucine; Male; Methyltyrosines; Mice; Naloxone; Protease Inhibitors; Thiorphan; Tiopronin

1984
Leucinal inhibits brain aminopeptidase activity and potentiates analgesia induced by leu-enkephalen.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:5

    Topics: Aminopeptidases; Analgesia; Animals; Brain; Chemical Phenomena; Chemistry; Enkephalin, Leucine; Leucine; Male; Mice; Nociceptors; Rats; Rats, Inbred Strains

1983
Nociception, enkephalin content and dipeptidyl carboxypeptidase activity in brain of mice treated with exopeptidase inhibitors.
    Neuropharmacology, 1982, Volume: 21, Issue:7

    Topics: Animals; Brain; Corpus Striatum; Endopeptidases; Enkephalin, Methionine; Enkephalins; Exopeptidases; Female; Leucine; Mice; Neprilysin; Nociceptors; Protease Inhibitors; Thiorphan; Tiopronin

1982
Enkephalin degradation in the guinea-pig ileum: effect of aminopeptidase inhibitors, puromycin and bestatin.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:2

    Topics: Aminopeptidases; Animals; Enkephalins; Guinea Pigs; Ileum; Leucine; Male; Puromycin

1983
Enkephalin degrading enzymes in cerebrospinal fluid.
    Life sciences, 1983, Aug-01, Volume: 33, Issue:5

    Topics: Cerebrospinal Fluid; Enkephalins; Humans; Kinetics; Leucine; Protease Inhibitors

1983
[Inhibitory effect of leu-enkephalin on gastric secretion in dogs].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:6

    Topics: Animals; Anura; Denervation; Dogs; Endorphins; Enkephalins; Gastric Juice; Gastric Mucosa; Gastrins; Hydrogen-Ion Concentration; In Vitro Techniques; Leucine; Rana temporaria; Stomach; Time Factors

1980
Separation and characterization of a dipeptidyl aminopeptidase that degrades enkephalins from monkey brain.
    Biochemical and biophysical research communications, 1982, Mar-30, Volume: 105, Issue:2

    Topics: Aminopeptidases; Animals; Brain; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Endorphins; Enkephalins; Leucine; Macaca fascicularis; Puromycin

1982
Central neuropharmacology of D-Ala2-Met-enkephalinamide and its interactions with taurine in rats.
    Advances in experimental medicine and biology, 1981, Volume: 139

    Topics: Analgesia; Animals; Catatonia; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Humans; Leucine; Male; Rats; Rats, Inbred Strains; Seizures; Taurine

1981
Effects of taurine and gamma-aminobutyric acid on akinesia and analgesia induced by D-Ala2-Met-enkephalinamide in rats.
    Peptides, 1980,Summer, Volume: 1, Issue:2

    Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Kinetics; Leucine; Male; Movement; Rats; Taurine

1980
[Some features of enkephalin metabolism in the rat brain after administration of bestatin].
    Biokhimiia (Moscow, Russia), 1993, Volume: 58, Issue:7

    Topics: Aminopeptidases; Animals; Brain; Carboxypeptidase H; Carboxypeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Neprilysin; Rats

1993
Hepatic inactivation of Leu-enkephalin.
    Regulatory peptides, 1996, Dec-03, Volume: 67, Issue:2

    Topics: Animals; Biliary Tract; Biotransformation; CD13 Antigens; Cell Membrane; Enkephalin, Leucine; Hydrolysis; Iodine Radioisotopes; Leucine; Liver; Male; Mice; Perfusion; Protease Inhibitors; Rats; Rats, Wistar; Succinimides; Tritium; Tyrosine

1996
Characterization of the decline in alcohol consumption by aminopeptidase inhibition.
    Drug and alcohol dependence, 1996, Dec-11, Volume: 43, Issue:3

    Topics: Alcohol Drinking; Aminopeptidases; Angiotensin II; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Drinking Behavior; Enkephalins; Imidazoles; Leucine; Losartan; Male; Naltrexone; Rats; Rats, Wistar; Tetrazoles

1996
Differential effect of intestinal neuropeptides on invasion and migration of colon carcinoma cells in vitro.
    Cancer letters, 1997, Jun-03, Volume: 116, Issue:1

    Topics: Adenocarcinoma; Animals; Biocompatible Materials; Calcitonin Gene-Related Peptide; Cell Division; Cell Movement; Colforsin; Collagen; Colonic Neoplasms; Dideoxyadenosine; Dose-Response Relationship, Drug; Drug Combinations; Enkephalins; Laminin; Leucine; Mice; Neoplasm Invasiveness; Neurokinin A; Neuropeptide Y; Neuropeptides; Proteoglycans; Somatostatin; Substance P; Tumor Cells, Cultured; Vasoactive Intestinal Peptide

1997
Characterisation of neprilysin (EC 3.4.24.11) S2' subsite.
    FEBS letters, 1997, Jul-07, Volume: 411, Issue:1

    Topics: Animals; Arginine; Binding Sites; COS Cells; Enkephalins; Gene Expression; Hydrolysis; Kinetics; Leucine; Mutagenesis, Site-Directed; Neprilysin; Substrate Specificity

1997
Rat jejunal permeability and metabolism of mu-selective tetrapeptides in gastrointestinal fluids from humans and rats.
    Pharmaceutical research, 1997, Volume: 14, Issue:12

    Topics: Amidines; Animals; Drug Stability; Enkephalins; Gastric Juice; Humans; Intestinal Absorption; Jejunum; Leucine; Male; Microvilli; Oligopeptides; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Sulfones; Thiorphan

1997
Enkephalin-processing oligopeptidases in cobra venom: inhibition by thiorphan and bestatin reveals co-operative actions.
    Toxicon : official journal of the International Society on Toxinology, 1998, Volume: 36, Issue:5

    Topics: Aminopeptidases; Animals; Drug Synergism; Elapid Venoms; Elapidae; Enkephalins; In Vitro Techniques; Leucine; Peptide Hydrolases; Protease Inhibitors; Substrate Specificity; Thiorphan

1998
The role of aminopeptidase N in Met-enkephalin modulated superoxide anion release.
    Immunopharmacology, 1999, Volume: 41, Issue:1

    Topics: Adult; Analgesics; Analgesics, Opioid; CD13 Antigens; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Leucine; Male; Neutrophils; Oligopeptides; Protease Inhibitors; Superoxides

1999
Spectroscopic evidence of beta-turn in N-glycated peptidomimetics related to leucine-enkephalin.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2000, Nov-01, Volume: 56A, Issue:12

    Topics: Enkephalins; Glycopeptides; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Mimicry; Polysaccharides; Protein Conformation; Spectroscopy, Fourier Transform Infrared

2000
Influence of solvents and leucine configuration at position 5 on tryptophan fluorescence in cyclic enkephalin analogues.
    Biopolymers, 2001, Apr-05, Volume: 58, Issue:4

    Topics: Enkephalins; Fluorescence; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Protein Conformation; Solvents; Spectrometry, Fluorescence; Tryptophan

2001
Fluorescence decay time distribution analysis of cyclic enkephalin analogues; influence of solvent and Leu configuration in position 5 on conformation.
    Acta biochimica Polonica, 2001, Volume: 48, Issue:1

    Topics: Enkephalins; Leucine; Models, Chemical; Models, Statistical; Protein Conformation; Spectrometry, Fluorescence; Tryptophan

2001
A new water-soluble N-protecting group, 2-(phenyl(methyl)sulfonio)ethyloxycarbonyl tetrafluoroborate, and its application to solid phase peptide synthesis in water.
    Journal of peptide science : an official publication of the European Peptide Society, 2001, Volume: 7, Issue:12

    Topics: Amides; Borates; Boric Acids; Chromatography, High Pressure Liquid; Enkephalins; Indicators and Reagents; Leucine; Models, Chemical; Peptide Biosynthesis; Water

2001
Dual modulation of gabaergic transmission by metabotropic glutamate receptors in rat ventral tegmental area.
    Neuroscience, 2003, Volume: 119, Issue:2

    Topics: Anesthetics, Local; Animals; Bicuculline; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrophysiology; Enkephalins; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Leucine; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Neural Conduction; Neural Inhibition; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Ventral Tegmental Area

2003
Electrospray mass spectrometric study of anionic complexes of enkephalins with Cu(II): regioselective distinction of Leu/Ile at the C-terminus induced by metal reduction.
    Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:12

    Topics: Anions; Copper; Enkephalins; Isoleucine; Leucine; Macromolecular Substances; Metals; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Peptide Fragments; Spectrometry, Mass, Electrospray Ionization

2003
Enkephalins: Raman spectral analysis and comparison as function of pH 1-13.
    Biopolymers, 2003, Volume: 72, Issue:5

    Topics: Cell Line, Tumor; Circular Dichroism; Enkephalins; Humans; Hydrogen-Ion Concentration; Leucine; Methionine; Models, Chemical; Protein Conformation; Spectrum Analysis, Raman; Tyrosine

2003
Determination of the activation energy for unimolecular dissociation of a non-covalent gas-phase peptide: substrate complex by infrared multiphoton dissociation fourier transform ion cyclotron resonance mass spectrometry.
    Journal of the American Society for Mass Spectrometry, 2003, Volume: 14, Issue:11

    Topics: Bradykinin; Cyclotrons; Enkephalins; Fourier Analysis; Indicators and Reagents; Infrared Rays; Leucine; Mass Spectrometry; Oligopeptides; Receptors, Peptide

2003
Anionic copper complex fragmentations from enkephalins under low-energy collision-induced dissociation in an ion trap mass spectrometer.
    Journal of mass spectrometry : JMS, 2004, Volume: 39, Issue:8

    Topics: Anions; Copper; Enkephalins; Glycine; Isoleucine; Leucine; Macromolecular Substances; Peptide Fragments; Spectrometry, Mass, Electrospray Ionization

2004
Establishing low-energy sequential decomposition pathways of leucine enkephalin and its N- and C-terminus fragments using multiple-resonance CID in quadrupolar ion guide.
    Journal of the American Society for Mass Spectrometry, 2004, Volume: 15, Issue:12

    Topics: Enkephalins; Leucine; Spectrometry, Mass, Electrospray Ionization

2004
Identification of modulating residues defining the catalytic cleft of insulin-regulated aminopeptidase.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2008, Volume: 86, Issue:3

    Topics: Amino Acid Sequence; Catalytic Domain; Cell Line; Cystinyl Aminopeptidase; Enkephalin, Leucine; Humans; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Recombinant Proteins; Sequence Homology, Amino Acid; Vasopressins

2008
Analysis of samples stored as individual plugs in a capillary by electrospray ionization mass spectrometry.
    Analytical chemistry, 2009, Aug-01, Volume: 81, Issue:15

    Topics: Air; Electrophoresis, Capillary; Enkephalins; Leucine; Microfluidic Analytical Techniques; Peptide Fragments; Solvents; Spectrometry, Mass, Electrospray Ionization; Water

2009
Photodissociation of protonated leucine-enkephalin in the VUV range of 8-40 eV.
    The Journal of chemical physics, 2011, Jan-14, Volume: 134, Issue:2

    Topics: Enkephalins; Leucine; Photochemical Processes; Protons; Quantum Theory; Ultraviolet Rays

2011
Pain inhibition by blocking leukocytic and neuronal opioid peptidases in peripheral inflamed tissue.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:12

    Topics: Alanine; Amino Acid Sequence; Animals; Antibodies; CD13 Antigens; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enzyme Inhibitors; Flow Cytometry; Hindlimb; Inflammation; Leucine; Leukocytes; Male; Narcotic Antagonists; Neprilysin; Neurons; Opioid Peptides; Pain; Pain Threshold; Phosphinic Acids; Rats; Rats, Wistar; Receptors, Opioid; Thiorphan

2012
Nanosolvation-induced stabilization of a protonated peptide dimer isolated in the gas phase.
    Angewandte Chemie (International ed. in English), 2013, Jul-08, Volume: 52, Issue:28

    Topics: Dimerization; Enkephalins; Gases; Leucine; Mass Spectrometry; Molecular Conformation; Peptides; Protons; Quantum Theory; Thermodynamics; Ultraviolet Rays

2013
Spinal ERK2 activation through δ2-opioid receptors contributes to nociceptive behavior induced by intrathecal injection of leucine-enkephalin.
    Peptides, 2014, Volume: 54

    Topics: Animals; Arginine; Behavior, Animal; Butadienes; Enkephalin, Leucine; Enzyme Activation; Glycopeptides; Injections, Spinal; Leucine; Male; Mice, Inbred Strains; Mitogen-Activated Protein Kinase 1; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitriles; Nociception; Protease Inhibitors; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Spinal Cord

2014
Effects of Leucin-Enkephalins on Surface Characteristics and Morphology of Model Membranes Composed of Raft-Forming Lipids.
    The Journal of membrane biology, 2016, Volume: 249, Issue:3

    Topics: Enkephalins; Leucine; Membrane Lipids; Membrane Microdomains; Surface Tension

2016
VUV action spectroscopy of protonated leucine-enkephalin peptide in the 6-14 eV range.
    The Journal of chemical physics, 2015, Dec-28, Volume: 143, Issue:24

    Topics: Enkephalins; Leucine; Peptides; Photolysis; Protons; Spectrophotometry, Ultraviolet; Ultraviolet Rays

2015
Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala.
    Molecular pharmacology, 2020, Volume: 98, Issue:4

    Topics: Amygdala; Animals; Captopril; Electrical Synapses; Enkephalins; Glutamic Acid; Leucine; Male; Neprilysin; Protease Inhibitors; Proteolysis; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiorphan

2020
Collision Cross-Section Measurements of Collision-Induced Dissociation Precursor and Product Ions in an FTICR-MS and an IM-MS: A Comparative Study.
    Journal of the American Society for Mass Spectrometry, 2022, Sep-07, Volume: 33, Issue:9

    Topics: Crown Ethers; Enkephalin, Leucine; Ions; Leucine; Mass Spectrometry

2022
The opioid peptide leucine-enkephalin disrupts seasonal and gonadotropin-induced ovarian recrudescence in the gecko Hemidactylus frenatus.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2023, Volume: 283

    Topics: Animals; Enkephalin, Leucine; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Leucine; Lizards; Opioid Peptides; Ovarian Follicle; Ovary; Seasons

2023