enkephalin, leucine has been researched along with kelatorphan in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (53.57) | 18.7374 |
| 1990's | 11 (39.29) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Daugé, V; Duffy, T; Kalivas, PW; Roques, BP | 1 |
| De Witte, P; Gewiss, M; Heidbreder, C; Lallemand, S; Roques, BP | 1 |
| Durieux, C; Fournié-Zaluski, MC; Roques, BP; Ruiz-Gayo, M | 1 |
| Fournié-Zaluski, MC; Maldonado, R; Roques, BP | 1 |
| Calenco-Choukroun, G; Daugé, V; Gacel, G; Roques, BP | 1 |
| Costentin, J; Dourmap, N; Michael-Titus, A | 1 |
| Costentin, J; Dourmap, N; Michael-Titus, A; Schwartz, JC | 1 |
| Fournié-Zaluski, MC; Noble, F; Peyroux, J; Roques, BP; Schmidt, C | 1 |
| Calenco-Choukroun, G; Daugé, V; Féger, J; Roques, BP | 1 |
| Daugé, V; Feger, J; Maldonado, R; Roques, BP | 1 |
| Daugé, V; Roques, BP; Rossignol, P | 2 |
| Fournié-Zaluski, MC; Peyroux, J; Roques, BP; Schmidt, C; Soleilhac, JM; Xie, J | 1 |
| de Witte, P; Heidbreder, C; Roques, BP | 1 |
| Fournie-Zaluski, MC; Guilbaud, G; Kayser, V; Roques, BP | 1 |
| Dickenson, AH; Roques, BP; Sullivan, AF | 1 |
| Dauge, V; Dickenson, AH; Roques, BP; Zajac, JM | 1 |
| Fournie-Zaluski, MC; Glowinski, J; Hamon, M; Petit, F; Roques, BP | 1 |
| Dickenson, AH; Feeney, C; Fournie-Zaluski, MC; Roques, BP; Sullivan, A | 1 |
| Dickenson, AH; Fournie-Zaluski, MC; Roques, BP; Sullivan, AF | 1 |
| Bednar, I; Forsberg, G; Södersten, P | 1 |
| Christie, MJ; North, RA; Roques, BP; Williams, JT | 1 |
| Bouboutou, R; Bourgoin, S; Cesselin, F; Devin, J; Fournie-Zaluski, MC; Hamon, M; Roques, B; Waksman, G | 1 |
| Bouboutou, R; Devin, J; Fournié-Zaluski, MC; Roques, BP; Waksman, G | 1 |
| Bouboutou, R; Chaillet, P; Cherot, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Waksman, G | 1 |
| Baghdoyan, HA; Cronin, A; Keifer, JC; Lydic, R | 1 |
| Boudinot, E; Denavit-Saubié, M; Fournié-Zaluski, M; Foutz, AS; Morin-Surun, M; Roques, BP | 1 |
| Bansal, N; Fonseca, A; Gillis, J; Gulati, A; Horine, SV; Kuppalli, S; Mendelson, A; Southerland, WA | 1 |
1 review(s) available for enkephalin, leucine and kelatorphan
| Article | Year |
|---|---|
Dual Enkephalinase Inhibitors and Their Role in Chronic Pain Management.
Topics: CD13 Antigens; Chronic Pain; Dipeptides; Disulfides; Enkephalins; Enzyme Inhibitors; Humans; Neprilysin; Phenylalanine; Propionates; Propylamines | 2021 |
27 other study(ies) available for enkephalin, leucine and kelatorphan
| Article | Year |
|---|---|
Effect of inhibiting enkephalin catabolism in the VTA on motor activity and extracellular dopamine.
Topics: Amino Acid Sequence; Animals; Dipeptides; Dopamine; Enkephalins; Male; Microinjections; Molecular Sequence Data; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali | 1992 |
Inhibition of enkephalin metabolism and activation of mu- or delta-opioid receptors elicit opposite effects on reward and motility in the ventral mesencephalon.
Topics: Animals; Brain; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mesencephalon; Motor Activity; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Reward; Self Stimulation | 1992 |
Stimulation of delta-opioid receptors reduces the in vivo binding of the cholecystokinin (CCK)-B-selective agonist [3H]pBC 264: evidence for a physiological regulation of CCKergic systems by endogenous enkephalins.
Topics: Analgesics; Analgesics, Opioid; Animals; Cholecystokinin; Dipeptides; Disulfides; Dose-Response Relationship, Drug; Enkephalins; Male; Mice; Narcotic Antagonists; Peptide Fragments; Phenylalanine; Prodrugs; Receptors, Cholecystokinin; Receptors, Opioid | 1992 |
Attenuation of the morphine withdrawal syndrome by inhibition of catabolism of endogenous enkephalins in the periaqueductal gray matter.
Topics: Analgesics; Animals; Behavior, Animal; Body Temperature; Body Weight; Corticosterone; Dipeptides; Enkephalins; Hydroxamic Acids; Male; Morphine; Morphine Dependence; Naloxone; Neprilysin; Periaqueductal Gray; Phenylalanine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Thiorphan | 1992 |
Lesion of dopamine mesolimbic neurons blocks behavioral effects induced by the endogenous enkephalins but not by a mu-opioid receptor agonist.
Topics: Amino Acid Sequence; Analgesics; Animals; Behavior, Animal; Dipeptides; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Limbic System; Male; Molecular Sequence Data; Motor Activity; Neurons; Nucleus Accumbens; Oligopeptides; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tegmentum Mesencephali | 1991 |
Local enkephalins tonically modulate dopamine release in the striatum: a microdialysis study.
Topics: Amino Acid Sequence; Aminopeptidases; Analgesics; Animals; CD13 Antigens; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dipeptides; Dopamine; Enkephalins; Male; Molecular Sequence Data; Naltrexone; Neprilysin; Rats; Rats, Inbred Strains; Substrate Specificity | 1990 |
Role of delta opioid receptors in the effects of inhibitors of enkephalin-degrading peptidases on the horizontal and vertical components of locomotion in mice.
Topics: Aminopeptidases; Animals; CD13 Antigens; Dipeptides; Drug Synergism; Enkephalin, Leucine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Leucine; Locomotion; Male; Mice; Naloxone; Neprilysin; Phenylcarbamates; Prodrugs; Receptors, Opioid; Receptors, Opioid, delta; Sulfhydryl Compounds; Thiorphan | 1990 |
Analgesic responses elicited by endogenous enkephalins (protected by mixed peptidase inhibitors) in a variety of morphine-sensitive noxious tests.
Topics: Analgesics; Animals; Dipeptides; Dose-Response Relationship, Drug; Enkephalins; Hydroxamic Acids; Male; Mice; Morphine; Naloxone; Phenylalanine; Rats; Rats, Inbred Strains | 1991 |
Behavioral effects of endogenous or exogenous (mu, delta) opioid peptides: relation with DA mesolimbic pathways.
Topics: Animals; Dipeptides; Dopamine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydroxydopamines; Limbic System; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1990 |
Chronic blockade of D2 but not D1 dopamine receptors facilitates behavioural responses to endogenous enkephalins, protected by kelatorphan, administered in the accumbens in rats.
Topics: Animals; Behavior, Animal; Benzazepines; Dipeptides; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalins; Haloperidol; Injections; Male; Motor Activity; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, delta; Sulpiride | 1990 |
Blockade of dopamine receptors reverses the behavioral effects of endogenous enkephalins in the Nucleus caudatus but not in the Nucleus accumbens: differential involvement of delta and mu opioid receptors.
Topics: Animals; Apomorphine; Behavior, Animal; Caudate Nucleus; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Microinjections; Motor Activity; Nucleus Accumbens; Oligopeptides; Phenothiazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Septal Nuclei | 1989 |
New kelatorphan-related inhibitors of enkephalin metabolism: improved antinociceptive properties.
Topics: Analgesics; Animals; Dipeptides; Enkephalins; Male; Mice | 1989 |
Kelatorphan, a potent enkephalinases inhibitor, and opioid receptor agonists DAGO and DTLET, differentially modulate self-stimulation behaviour depending on the site of administration.
Topics: Animals; Behavior, Animal; Dextroamphetamine; Dipeptides; Electrodes, Implanted; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Injections; Injections, Intraventricular; Male; Neprilysin; Nucleus Accumbens; Oligopeptides; Rats; Rats, Inbred Strains; Self Stimulation | 1989 |
Potent antinociceptive effects of kelatorphan (a highly efficient inhibitor of multiple enkephalin-degrading enzymes) systemically administered in normal and arthritic rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Dipeptides; Dose-Response Relationship, Drug; Enkephalins; Enzyme Inhibitors; Male; Naloxone; Pain; Rats; Rats, Inbred Strains | 1989 |
Evidence that endogenous enkephalins and a delta opioid receptor agonist have a common site of action in spinal antinociception.
Topics: Analgesia; Animals; Dipeptides; Enkephalin, Leucine; Enkephalins; Oligopeptides; Rats; Receptors, Opioid; Spinal Cord | 1988 |
[Enkephalins and analgesia].
Topics: Analgesia; Dipeptides; Enkephalins; Humans; Receptors, Opioid; Spinal Cord | 1988 |
Comparison of the behavioural effects induced by administration in rat nucleus accumbens or nucleus caudatus of selective mu and delta opioid peptides or kelatorphan an inhibitor of enkephalin-degrading-enzymes.
Topics: Animals; Behavior, Animal; Caudate Nucleus; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Motor Activity; Naloxone; Neprilysin; Norepinephrine; Nucleus Accumbens; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1988 |
Further evidence for a role of delta-opiate receptors in the presynaptic regulation of newly synthesized dopamine release.
Topics: Animals; Corpus Striatum; Dipeptides; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Nucleus Accumbens; Oligopeptides; Potassium; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Synapses | 1986 |
Evidence that endogenous enkephalins produce delta-opiate receptor mediated neuronal inhibitions in rat dorsal horn.
Topics: Animals; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Nerve Fibers; Neural Inhibition; Rats; Receptors, Opioid; Receptors, Opioid, delta; Spinal Cord | 1986 |
Prevention of degradation of endogenous enkephalins produces inhibition of nociceptive neurones in rat spinal cord.
Topics: Action Potentials; Animals; Dipeptides; Enkephalins; Leucine; Male; Naloxone; Nerve Fibers; Neural Inhibition; Neurons, Afferent; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Tiopronin | 1987 |
Inhibition of sexual behavior in female rats by intracerebral injections of Met-enkephalin in combination with an inhibitor of enkephalin degrading enzymes.
Topics: Animals; Brain; Dipeptides; Enkephalin, Leucine; Enkephalin, Methionine; Enzyme Inhibitors; Female; Injections, Intraventricular; Injections, Subcutaneous; Lordosis; Periaqueductal Gray; Rats; Rats, Inbred Strains; Sexual Behavior, Animal | 1987 |
Potentiation of enkephalin action by peptidase inhibitors in rat locus ceruleus in vitro.
Topics: Analgesics; Animals; Dipeptides; Drug Synergism; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Locus Coeruleus; Neurons; Protease Inhibitors; Rats; Structure-Activity Relationship | 1987 |
In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain.
Topics: Aminopeptidases; Animals; Brain; Brain Chemistry; Corpus Striatum; Dipeptides; Enkephalin, Methionine; Enkephalins; Hydrolysis; In Vitro Techniques; Leucine; Mice; Protease Inhibitors; Rats; Thiorphan; Tiopronin | 1985 |
Bidentate peptides: highly potent new inhibitors of enkephalin degrading enzymes.
Topics: Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Chromatography, Gel; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Humans; Hydroxamic Acids; Rabbits; Rats; Structure-Activity Relationship | 1984 |
Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes.
Topics: Aminopeptidases; Analgesics; Animals; Brain; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kidney; Leucine; Neprilysin; Protease Inhibitors; Rabbits; Rats; Reaction Time; Thiorphan; Tiopronin | 1984 |
Opioid inhibition of rapid eye movement sleep by a specific mu receptor agonist.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cats; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Neprilysin; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Respiration; Reticular Formation; Sleep, REM; Wakefulness | 1995 |
Effects of the potent analgesic enkephalin-catabolizing enzyme inhibitors RB101 and kelatorphan on respiration.
Topics: Analgesics; Animals; Cats; Dipeptides; Disulfides; Enkephalins; Enzyme Inhibitors; Mice; Naloxone; Narcotic Antagonists; Phenylalanine; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Respiration | 2001 |