enkephalin, leucine has been researched along with kainic acid in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (38.10) | 18.7374 |
| 1990's | 31 (49.21) | 18.2507 |
| 2000's | 6 (9.52) | 29.6817 |
| 2010's | 2 (3.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Costa, E; Hong, JS; Yang, HY | 1 |
| Fuxe, K; Goldstein, M; Hökfelt, T; Jonsson, G; Schwarcz, R; Terenius, L | 1 |
| Biggio, G; Casu, M; Corda, MG; Di Bello, C; Gessa, GL | 1 |
| Childers, SR; Coyle, JT; Schwarcz, R; Snyder, SH | 1 |
| Biggio, G; Casu, M; Corda, MG; Gessa, GL | 1 |
| Dray, F; Gros, C; Llorens, C; Malfroy, B; Pollard, H; Pradelles, P; Schwartz, JC | 1 |
| Carenzi, A; Della Bella, D; Frigeni, V | 1 |
| Dray, F; Gros, C; Llorens, C; Pollard, H; Schwartz, JC | 1 |
| Llorens, C; Malfroy, B; Schwartz, JC; Swerts, JP | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R | 3 |
| Liu, YF; Quirion, R | 1 |
| Costentin, J; Dourmap, N; Michael-Titus, A | 1 |
| Douglass, J; Grimes, L; Hong, JS; Lee, PH; Shook, J | 1 |
| Bose, R; Glavin, GB; Hall, A; Pinsky, C | 1 |
| Aanonsen, LM; Wilcox, GL | 2 |
| Beal, MF; Burd, GD; Landis, DM; Marshall, PE; Martin, JB | 1 |
| Grimes, L; Hong, JS; Kanamatsu, T; McGinty, JF; Obie, J; Sabol, S; Yoshikawa, K | 1 |
| Gall, C | 1 |
| Grimes, L; Hong, J; McGinty, J; Mitchell, C; Obie, J; Tilson, H | 1 |
| Aitken, PG | 1 |
| Kehl, SJ; McLennan, H | 1 |
| Antkiewicz-Michaluk, L; Havemann, U; Kuschinsky, K; Vetulani, J; Wellstein, A | 1 |
| Fuxe, K; Goldstein, M; Hökfelt, T; Schwarcz, R; Terenius, L | 1 |
| Costa, E; Gillin, JC; Hong, JS; Wood, PL; Yang, HY | 2 |
| Crossman, AR; Lee, LA; Slater, P | 1 |
| Cuello, AC; Del Fiacco, M; Paxinos, G; Priestley, JV; Somogyi, P | 1 |
| Isaacson, RL; Lanthorn, TH | 1 |
| Kaczmarek, L; Kamińska, B; Lasoń, W; Lukasiuk, K; Nowicka, DZ; Przewłocka, B; Przewłocki, R | 1 |
| Applegate, CD; Piekut, DT; Pretel, S | 1 |
| Christakos, S; Devinsky, O; Howells, R; Lee, S; Lothman, E; Miskovsky, J; Williamson, J | 1 |
| Calza, L; Ceccatelli, S; Giardino, L; Hökfelt, T | 1 |
| Cunningham, JR; Neal, MJ; Paterson, SJ | 1 |
| Ahn, A; Beal, MF; DiFiglia, M; Roberts, RC; Swartz, KJ | 1 |
| Shen, S; Yuan, XR; Zhu, SM | 1 |
| Bürki, C; Ehrenberger, K; Felix, D | 1 |
| Citri, Y; Hevroni, D; Israeli, D; Naot, D; Nedivi, E | 1 |
| Gao, X; Hong, JS; Zhang, WQ | 1 |
| Bizon, JL; Gallagher, M; Nicolle, MM | 1 |
| Martin, G; Nie, Z; Siggins, GR | 1 |
| Bing, G; Hong, JS; Simpson, JN; Zhang, WQ | 1 |
| Bing, G; Bronstein, D; Hong, JS; Kim, HC; Suh, HW; Wilson, B | 1 |
| Kim, YH; Song, DK; Suh, HW; Won, JS | 1 |
| Bing, G; Bing, R; Feng, Z; Hong, JS; Hudson, P; Jin, L; Wilson, B; Zhang, W | 1 |
| Friedman, LK | 1 |
| Fischer-Colbrie, R; Schwarzer, C; Sperk, G; Tsunashima, K; Wolkersdorfer, M | 1 |
| Budai, D; Fields, HL | 1 |
| Jhoo, WK; Kim, HC; Kim, YH; Song, DK; Suh, HW; Suh, JH; Wie, MB; Won, JS | 1 |
| Labuz, D; Mika, J; Przewłocka, B; Przewłocki, R; Ziółkowska, B | 1 |
| Huh, SO; Im, YB; Kim, YH; Song, DK; Suh, HW; Won, JS | 1 |
| Ben, LH; Luo, SQ; Pei, G; Xin, SM; Zhao, J | 1 |
| Huh, SO; Kim, YH; Song, DK; Suh, HW; Won, JS | 1 |
| Feng, ZH; Hong, JS; Li, DD; Zhang, WQ | 1 |
| Choi, MR; Choi, SS; Kim, YH; Lee, JK; Suh, HW; Won, JS | 1 |
| Einheber, S; Milner, TA; Pierce, JP; Skyers, PS | 1 |
| Maidment, NT; Rocha, L | 1 |
| Cho, GJ; Choi, WS; Kang, SS; Kim, DW; Kim, YH; Noh, HS | 1 |
| Deroche-Gamonet, V; Izawa, R; Jaber, M; Kellendonk, C; Le Moal, M; Piazza, PV; Sillaber, I; Tronche, F | 1 |
| Aigner, C; Herzog, H; Schunk, E; Schwarzer, C; Stefanova, N; Wenning, G | 1 |
| Alvarez-Fischer, D; Bandmann, O; Fritsch, B; Grundmann, M; Hartmann, A; Lu, L; Möller, JC; Oertel, WH; Samans, B; Schaefer, MK | 1 |
2 review(s) available for enkephalin, leucine and kainic acid
| Article | Year |
|---|---|
Striato-cerebellar pathway controlling cyclic GMP content in the cerebellum: role of dopamine, GABA and enkephalins.
Topics: Animals; Apomorphine; Cerebellum; Corpus Striatum; Cyclic GMP; Dopamine; Enkephalins; gamma-Aminobutyric Acid; Haloperidol; Harmaline; Isoniazid; Kainic Acid; Neural Pathways; Rats | 1978 |
Endorphins and endorphin receptors in striatum: relationships with dopaminergic neurons.
Topics: Animals; Corpus Striatum; Dopamine; Endorphins; Enkephalins; Kainic Acid; Kinetics; Models, Biological; Neurons; Radioimmunoassay; Radioligand Assay; Rats; Receptors, Opioid | 1978 |
61 other study(ies) available for enkephalin, leucine and kainic acid
| Article | Year |
|---|---|
On the location of methionine enkephalin neurons in rat striatum.
Topics: Animals; Corpus Striatum; Endorphins; Enkephalins; Kainic Acid; Neurons; Rats; Tyrosine 3-Monooxygenase | 1977 |
Ibotenic acid-induced neuronal degeneration: a morphological and neurochemical study.
Topics: Animals; Brain; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; Enkephalins; Fluorescent Antibody Technique; Glutamate Decarboxylase; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Nerve Degeneration; Oxazoles; Rats; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 1979 |
Stimulation of dopamine synthesis in caudate nucleus by intrastriatal enkephalins and antagonism by naloxone.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dopamine; Endorphins; Enkephalins; Homovanillic Acid; Kainic Acid; Male; Naloxone; Rats; Receptors, Dopamine; Receptors, Opioid | 1978 |
Radioimmunoassay of enkephalins: levels of methionine- and leucine-enkephalin in morphine-dependent and kainic acid-lesioned rat brains.
Topics: Animals; Antibody Specificity; Brain Chemistry; Endorphins; Enkephalins; Humans; Kainic Acid; Male; Microwaves; Morphine Dependence; Naloxone; Pyrrolidines; Radioimmunoassay; Rats; Receptors, Opioid | 1978 |
Synaptic localization of opiate receptors in rat striatum.
Topics: Animals; Corpus Striatum; Enkephalins; Kainic Acid; Male; Morphine Derivatives; Neural Pathways; Rats; Receptors, Opioid; Substantia Nigra; Synapses | 1978 |
Localization of opiate receptors and enkephalins in the rat striatum in relationship with the nigrostriatal dopaminergic system: lesion studies.
Topics: Animals; Binding Sites; Corpus Striatum; Dopamine; Endorphins; Enkephalins; Hydroxydopamines; Kainic Acid; Nerve Degeneration; Neural Pathways; Neurons; Rats; Receptors, Dopamine; Receptors, Opioid; Substantia Nigra | 1978 |
Regional distribution of a high-affinity enkephalin-degrading peptidase ('enkephalinase') and effects of lesions suggest localization in the vicinity of opiate receptors in brain.
Topics: Animals; Brain; Brain Chemistry; Brain Stem; Cerebellum; Cerebral Cortex; Corpus Striatum; Endopeptidases; Enkephalins; Hippocampus; Hypothalamus; Kainic Acid; Mice; Receptors, Opioid | 1979 |
The effects of excitatory amino acids on proenkephalin and prodynorphin mRNA levels in the hippocampal dentate gyrus of the rat; an in situ hybridization study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Enkephalins; Functional Laterality; Gene Expression; Hippocampus; Kainic Acid; Kinetics; Male; Microinjections; N-Methylaspartate; Nucleic Acid Hybridization; Protein Precursors; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; RNA, Messenger | 1992 |
Modulatory role of glutathione on mu-opioid, substance P/neurokinin-1, and kainic acid receptor binding sites.
Topics: Animals; Binding Sites; Cholic Acids; Detergents; Dithiothreitol; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glutathione; Guanylyl Imidodiphosphate; Kainic Acid; Receptors, Kainic Acid; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, mu; Solubility; Substance P; Swine | 1992 |
The prodynorphin system in the rat hippocampus is differentially influenced by kainic acid and pentetrazole.
Topics: Animals; Autoradiography; Enkephalins; Hippocampus; In Situ Hybridization; In Vitro Techniques; Kainic Acid; Male; Pentylenetetrazole; Protein Precursors; Rats; Rats, Wistar; Reference Values; RNA, Messenger; Seizures; Sulfur Radioisotopes | 1992 |
Differential effect of intrastriatal kainic acid on the modulation of dopamine release by mu- and delta-opioid peptides: a microdialysis study.
Topics: Animals; Corpus Striatum; Dialysis; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Extracellular Space; Injections; Kainic Acid; Male; Rats; Rats, Inbred Strains | 1992 |
Systemic administration of kainic acid differentially regulates the levels of prodynorphin and proenkephalin mRNA and peptides in the rat hippocampus.
Topics: Amino Acid Isomerases; Animals; Carrier Proteins; Endorphins; Enkephalins; Gene Expression Regulation; Hippocampus; Injections, Subcutaneous; Kainic Acid; Male; Peptidylprolyl Isomerase; Protein Precursors; Rats; Rats, Inbred F344; RNA, Messenger; Seizures | 1991 |
Opioid involvement in epileptogenic and neurovisceral activity.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Digestive System; Enkephalin, Leucine; Enkephalin, Methionine; Epilepsy; Kainic Acid; Male; Mice; Naloxone; Nervous System; Pyrrolidines; Receptors, Opioid | 1990 |
The release of alpha-neoendorphin from rat hippocampus following kainic acid-induced seizures.
Topics: Animals; Endorphins; Enkephalins; Hippocampus; Kainic Acid; Male; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Seizures | 1990 |
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phencyclidine; Quisqualic Acid; Spinal Cord; Substance P; Tetrazoles; Valine | 1986 |
Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and sigma agonists.
Topics: Animals; Aspartic Acid; Enkephalins; Hot Temperature; Kainic Acid; Male; Mice; N-Methylaspartate; Narcotics; Nociceptors; Oxadiazoles; Pain; Phencyclidine; Phentolamine; Quisqualic Acid; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1987 |
Excitotoxin lesions do not mimic the alteration of somatostatin in Huntington's disease.
Topics: Animals; Brain; Corpus Striatum; Disease Models, Animal; Enkephalin, Leucine; Humans; Huntington Disease; Ibotenic Acid; Immune Sera; Immunoassay; Kainic Acid; Male; Neurons; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Tissue Distribution | 1985 |
Kainic acid alters the metabolism of Met5-enkephalin and the level of dynorphin A in the rat hippocampus.
Topics: Animals; Dynorphins; Enkephalin, Methionine; Enkephalins; Hippocampus; Histocytochemistry; Immunochemistry; Kainic Acid; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred F344; RNA, Messenger; Seizures | 1986 |
Seizures induce dramatic and distinctly different changes in enkephalin, dynorphin, and CCK immunoreactivities in mouse hippocampal mossy fibers.
Topics: Animals; Cholecystokinin; Dynorphins; Enkephalins; Hippocampus; Immunochemistry; Kainic Acid; Mice; Nerve Fibers; Seizures | 1988 |
Enkephalin contained in dentate granule cells is important for kainic acid-induced wet dog shakes.
Topics: Animals; Enkephalins; Hippocampus; Kainic Acid; Male; Rats; Rats, Inbred F344; Stereotyped Behavior | 1986 |
Kainic acid and penicillin: differential effects on excitatory and inhibitory interactions in the CA1 region of the hippocampal slice.
Topics: Animals; Convulsants; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Neural Inhibition; Penicillins; Pyrrolidines; Rats; Rats, Inbred Strains | 1985 |
A pharmacological characterization of chloride- and potassium-dependent inhibitions in the CA3 region of the rat hippocampus in vitro.
Topics: Animals; Baclofen; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hippocampus; In Vitro Techniques; Kainic Acid; Neural Inhibition; Neural Pathways; Norepinephrine; Potassium; Rats; Synapses | 1985 |
Opioid-specific recognition sites of the mu- and the delta-type in rat striatum after lesions with kainic acid.
Topics: Animals; Corpus Striatum; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Kainic Acid; Kinetics; Male; Morphine Derivatives; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1984 |
Effects of chronic striatal kainate lesions on some dopaminergic parameters and enkephalin immunoreactive neurons in the basal ganglia.
Topics: Animals; Basal Ganglia; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; Endorphins; Enkephalins; Fluorescent Antibody Technique; Kainic Acid; Male; Neurons; Pyrrolidines; Rats; Spiperone; Tyrosine 3-Monooxygenase | 1980 |
Recurrent convulsions and hippocampal [Met5]-enkephalin content.
Topics: Animals; Electroshock; Endorphins; Enkephalin, Methionine; Enkephalins; Hippocampus; Injections; Kainic Acid; Male; Neurons; Rats; Recurrence; Seizures; Substance P; Time Factors | 1980 |
The role of the substantia nigra in a striatally-evoked motor response in the rat: effects of intranigral drugs and lesions.
Topics: Animals; Apomorphine; Atropine; Corpus Striatum; Electric Stimulation; Enkephalins; Female; Functional Laterality; gamma-Aminobutyric Acid; Kainic Acid; Mesencephalon; Movement; Nicotine; Pyrrolidines; Rats; Strychnine; Substance P; Substantia Nigra | 1981 |
Neuropeptides in striato-nigral pathways.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Clone Cells; Corpus Striatum; Endorphins; Enkephalin, Leucine; Enkephalins; Fluorescent Antibody Technique; Globus Pallidus; Kainic Acid; Male; Neurons; Rats; Substance P; Substantia Nigra | 1981 |
Hippocampal involvement in the pharmacologic induction of withdrawal-like behaviors.
Topics: Animals; Cyclazocine; Endorphins; Enkephalin, Methionine; Enkephalins; Escape Reaction; Ethylketocyclazocine; Hippocampus; Humans; Injections, Intraventricular; Kainic Acid; Morphine Dependence; Pyrrolidines; Rats; Serotonin; Shivering; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Changes of hippocampal Met-enkephalin content after recurrent motor seizures.
Topics: Animals; Endorphins; Enkephalins; Functional Laterality; Hippocampus; Kainic Acid; Male; Phenobarbital; Pyrrolidines; Rats; Seizures; Time Factors | 1980 |
Seizure related changes in the regulation of opioid genes and transcription factors in the dentate gyrus of rat hippocampus.
Topics: Animals; Behavior, Animal; Dentate Gyrus; DNA; Enkephalins; Gene Expression Regulation; Genes, fos; Genes, jun; Kainic Acid; Male; Opioid Peptides; Pentylenetetrazole; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Seizures; Transcription Factor AP-1; Transcription Factors | 1995 |
Seizure-induced activation of enkephalin- and somatostatin-synthesizing neurons.
Topics: Animals; Brain; Enkephalins; Gene Expression Regulation; Kainic Acid; Male; Neurons; Organ Specificity; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Seizures; Somatostatin | 1995 |
Changes in glutamate receptor and proenkephalin gene expression after kindled seizures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Blotting, Northern; Brain; Cerebellum; DNA Probes; Electric Stimulation; Enkephalins; Frontal Lobe; Gene Expression; Hippocampus; In Situ Hybridization; Kainic Acid; Kindling, Neurologic; Macromolecular Substances; Male; Organ Specificity; Parietal Lobe; Protein Precursors; Rats; Receptors, GABA; Receptors, Glutamate; RNA, Messenger; Seizures; Transcription, Genetic | 1994 |
Expression of enkephalin and dynorphin precursor mRNAs in brain areas of hypo-and hyperthyroid rat: effect of kainic acid injection.
Topics: Animals; Brain Chemistry; Dynorphins; Enkephalins; Excitatory Amino Acid Agonists; Hyperthyroidism; Hypothyroidism; In Situ Hybridization; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thyroxine; Triiodothyronine; Up-Regulation | 1995 |
Enhancement of retinal acetylcholine release by DAMGO: possibly a direct opioid receptor-mediated excitatory effect.
Topics: Acetylcholine; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Male; Rabbits; Rats; Receptors, Opioid, mu; Retina; Strychnine; Xanthines | 1994 |
Intrastriatal injections of quinolinic acid or kainic acid: differential patterns of cell survival and the effects of data analysis on outcome.
Topics: Analysis of Variance; Animals; Biomarkers; Cell Survival; Corpus Striatum; Enkephalins; Functional Laterality; Kainic Acid; Male; Microinjections; NADPH Dehydrogenase; Neurons; Quinolinic Acid; Rats; Rats, Sprague-Dawley | 1993 |
[Role of nucleus accumbens in cardiovascular activities and its relationship with opioid peptides in rats].
Topics: Animals; Blood Pressure; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Heart Rate; Kainic Acid; Locus Coeruleus; Microinjections; Naloxone; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1993 |
Enkephalin suppresses afferent cochlear neurotransmission.
Topics: Animals; Cochlea; Dendrites; Enkephalins; Guinea Pigs; Hair Cells, Auditory, Inner; Kainic Acid; N-Methylaspartate; Naloxone; Neurons, Afferent; Neurons, Efferent; Quisqualic Acid; Synaptic Transmission | 1993 |
Numerous candidate plasticity-related genes revealed by differential cDNA cloning.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA; Enkephalins; Gene Expression; Hippocampus; Kainic Acid; Male; Membrane Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Neuronal Plasticity; Protein Precursors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1993 |
[The effects of single administration of kainic acid on cellular signal transmission pathway and susceptibility to seizure].
Topics: Animals; Disease Susceptibility; Enkephalins; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression; Genes, fos; Genes, jun; Kainic Acid; Kindling, Neurologic; Male; Protein Precursors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction | 1995 |
In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long-Evans rats: relationship to spatial learning.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Kainic Acid; Male; Maze Learning; N-Methylaspartate; Organ Specificity; Prosencephalon; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Regression Analysis; Tritium | 1996 |
mu-Opioid receptors modulate NMDA receptor-mediated responses in nucleus accumbens neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; Kainic Acid; Male; N-Methylaspartate; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Synapses; Synaptic Transmission | 1997 |
Kainic acid-induced sprouting of dynorphin- and enkephalin-containing mossy fibers in the dentate gyrus of the rat hippocampus.
Topics: Animals; Dentate Gyrus; Dynorphins; Enkephalins; Immunohistochemistry; Injections, Subcutaneous; Kainic Acid; Male; Nerve Fibers; Rats; Rats, Inbred F344; Staining and Labeling | 1997 |
Dextromethorphan blocks opioid peptide gene expression in the rat hippocampus induced by kainic acid.
Topics: Animals; Dextromethorphan; Enkephalins; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Kainic Acid; Male; Neurotoxins; Protein Precursors; Rats; Rats, Inbred F344; RNA, Messenger; Seizures; Transcription, Genetic | 1997 |
The effect of cycloheximide on the regulation of proenkephalin and prodynorphin gene expressions induced by kainic acid in rat hippocampus.
Topics: Animals; Blotting, Western; Cycloheximide; Enkephalins; Gene Expression; Hippocampus; Kainic Acid; Male; Protein Precursors; Rats; Rats, Sprague-Dawley | 1997 |
A single dose of kainic acid elevates the levels of enkephalins and activator protein-1 transcription factors in the hippocampus for up to 1 year.
Topics: Animals; Enkephalins; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Rats; Rats, Inbred F344; Time Factors; Transcription Factor AP-1 | 1997 |
Developmental switch in phenotypic expression of preproenkephalin mRNA and 45Ca2+ accumulation following kainate-induced status epilepticus.
Topics: Animals; Autoradiography; Calcium; Calcium Radioisotopes; Enkephalins; Excitatory Amino Acid Agonists; Hippocampus; In Situ Hybridization; Kainic Acid; Phenotype; Protein Precursors; Rats; RNA, Messenger; Status Epilepticus | 1997 |
Limbic seizures induce neuropeptide and chromogranin mRNA expression in rat adrenal medulla.
Topics: Adrenal Medulla; Animals; Chromogranin A; Chromogranins; Enkephalins; Epinephrine; Gene Expression Regulation; Kainic Acid; Kinetics; Limbic System; Male; Neuropeptide Y; Norepinephrine; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Thiopental; Transcription, Genetic | 1997 |
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail | 1998 |
Phenidone blocks the increases of proenkephalin and prodynorphin gene expression induced by kainic acid in rat hippocampus: involvement of Fos-related antigene protein.
Topics: Animals; Enkephalins; Gene Expression; Hippocampus; Kainic Acid; Lipoxygenase Inhibitors; Male; Protein Precursors; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley | 1998 |
Evidence for Fos involvement in the regulation of proenkephalin and prodynorphin gene expression in the rat hippocampus.
Topics: Animals; Enkephalins; Gene Expression Regulation; Genes, fos; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Oligonucleotides, Antisense; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Seizures; Transcriptional Activation | 1998 |
The modulatory role of nitric oxide in the regulation of proenkephalin and prodynorphin gene expressions induced by kainic acid in rat hippocampus.
Topics: Animals; Arginine; DNA-Binding Proteins; Enkephalins; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor AP-1 | 1998 |
Attenuation of delta opioid receptor-mediated signaling by kainic acid in neural cells: involvement of protein kinase C and intracellular Ca2+.
Topics: Animals; Calcium; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Excitatory Amino Acid Agonists; GTP-Binding Proteins; Kainic Acid; Mice; Neurons; Nociceptin Receptor; Protein Kinase C; Receptors, AMPA; Receptors, Opioid; Receptors, Opioid, delta; Signal Transduction; Tumor Cells, Cultured | 1999 |
Effect of melatonin on the regulation of proenkephalin and prodynorphin mRNA levels induced by kainic acid in the rat hippocampus.
Topics: Animals; Enkephalins; Gene Expression Regulation; Genes, fos; Hippocampus; Injections, Intraperitoneal; Kainic Acid; Kinetics; Male; Melatonin; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Transcription Factor AP-1; Transcription, Genetic | 2000 |
The changes of AP-1 DNA binding activity and components in hippocampus of seizure-sensitive rat induced by kainate.
Topics: Animals; DNA; DNA-Binding Proteins; Enkephalins; Epilepsy; Hippocampus; Homeodomain Proteins; Kainic Acid; Male; Minor Histocompatibility Antigens; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Replication Protein C; Repressor Proteins; Saccharomyces cerevisiae Proteins | 1998 |
Possible roles of JNK pathway in the regulation of hippocampal proenkephalin and immediate early gene expression induced by kainic acid.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Enkephalins; Excitatory Amino Acid Agonists; Gene Expression Regulation; Genes, Immediate-Early; Hippocampus; Immunoblotting; Kainic Acid; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Precursors; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley | 2001 |
Increased mu-opioid receptor labeling is found on inner molecular layer terminals of the dentate gyrus following seizures.
Topics: Animals; Dendrites; Dentate Gyrus; Disease Models, Animal; Enkephalins; Immunohistochemistry; Kainic Acid; Male; Mossy Fibers, Hippocampal; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Seizures | 2003 |
Opioid peptide release in the rat hippocampus after kainic acid-induced status epilepticus.
Topics: Animals; Disease Models, Animal; Disease Progression; Down-Regulation; Dynorphins; Enkephalins; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Opioid Peptides; Rats; Rats, Wistar; Reaction Time; Status Epilepticus | 2003 |
Ketogenic diet decreases the level of proenkephalin mRNA induced by kainic acid in the mouse hippocampus.
Topics: Animals; Diet, Carbohydrate-Restricted; Diet, Protein-Restricted; Dietary Fats; Enkephalins; Epilepsy; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred ICR; Protein Precursors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Transcription Factor AP-1; Treatment Outcome | 2006 |
Gene expression regulation following behavioral sensitization to cocaine in transgenic mice lacking the glucocorticoid receptor in the brain.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dopamine Uptake Inhibitors; Dynorphins; Enkephalins; Gene Expression Regulation; GluK2 Kainate Receptor; In Situ Hybridization; Kainic Acid; Male; Mice; Mice, Transgenic; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Glucocorticoid; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance P; Synaptic Transmission | 2006 |
Kappa opioid receptor activation blocks progressive neurodegeneration after kainic acid injection.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; CA1 Region, Hippocampal; Enkephalins; Guanidines; Humans; Interneurons; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphinans; Neurodegenerative Diseases; Protein Precursors; Pyramidal Cells; Receptors, Opioid, kappa; Seizures | 2011 |
Prolonged generalized dystonia after chronic cerebellar application of kainic acid.
Topics: Animals; Brain; Cerebellum; Disease Models, Animal; Dystonia; Enkephalins; HSP72 Heat-Shock Proteins; Kainic Acid; Neurons; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats | 2012 |