enkephalin, leucine has been researched along with h-tyrosyl-cyclo(cysteinyl-phenylalanyl-penicillaminyl)-oh in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Heyl, DL; Medzihradsky, F; Mosberg, HI; Omnaas, JR; Smith, CB; Sobczyk-Kojiro, K | 1 |
| Gehrig, CA; Hruby, VJ; Nikiforovich, GV; Prakash, O | 1 |
| Bouzit, H; Hepp, AM; Heyl, DL; Johnson, TW; Kurtz, KR; Mousigian, C; Schmitter, SJ | 1 |
| Heyl, DL; Kroona, H; Lomize, AL; Ma, W; Mosberg, HI; Mousigian, C; Porreca, F; Sobczyk-Kojiro, K; Wang, C | 1 |
| Davis, P; Heyl, DL; Lomize, A; Mosberg, HI; Mousigian, C; Nordan, I; Omnaas, JR; Porreca, F | 1 |
| Lomize, AL; Mosberg, HI; Pogozheva, ID | 1 |
| Dua, RK; Lomize, AL; Mosberg, HI; Pogozheva, ID | 1 |
| Gao, P | 1 |
| Fowler, CB; Mosberg, HI | 1 |
| Balboni, G; Jutkiewicz, EM; Mosberg, HI; Torregrossa, MM; Watson, SJ; Woods, JH | 1 |
| Janecka, A; Janecki, T; Piekielna-Ciesielska, J; Wtorek, K | 1 |
1 review(s) available for enkephalin, leucine and h-tyrosyl-cyclo(cysteinyl-phenylalanyl-penicillaminyl)-oh
| Article | Year |
|---|---|
The search for opioid analgesics with limited tolerance liability.
Topics: Analgesics, Opioid; Animals; Enkephalins; Humans; Peptides; Peptides, Cyclic; Peptidomimetics; Quinolines; Receptors, Opioid, delta; Receptors, Opioid, mu | 2020 |
10 other study(ies) available for enkephalin, leucine and h-tyrosyl-cyclo(cysteinyl-phenylalanyl-penicillaminyl)-oh
| Article | Year |
|---|---|
Opioid receptor affinity and selectivity effects of second residue and carboxy terminal residue variation in a cyclic disulfide-containing opioid tetrapeptide.
Topics: Amino Acid Sequence; Animals; Carboxylic Acids; Disulfides; Enkephalins; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship | 1991 |
Topographical requirements for delta-selective opioid peptides.
Topics: Amino Acid Sequence; Computer Simulation; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Models, Molecular; Molecular Sequence Data; Oligopeptides; Protein Conformation | 1991 |
Substitution of aromatic and nonaromatic amino acids for the Phe3 residue in the delta-selective opioid peptide deltorphin I: effects on binding affinity and selectivity.
Topics: Amino Acid Sequence; Analgesics; Enkephalins; Kinetics; Molecular Sequence Data; Oligopeptides; Phenylalanine; Protein Conformation; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship; Tritium | 1994 |
Development of a model for the delta opioid receptor pharmacophore. 1. Conformationally restricted Tyr1 replacements in the cyclic delta receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13).
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cyclization; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Sequence Data; Muscle Contraction; Protein Conformation; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Thermodynamics; Tyrosine; Vas Deferens | 1994 |
Development of a model for the delta opioid receptor pharmacophore. 2. Conformationally restricted Phe3 replacements in the cyclic delta receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13).
Topics: Amino Acid Sequence; Aminobutyrates; Animals; Cyclization; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Molecular Sequence Data; Muscle Contraction; Phenylalanine; Protein Conformation; Receptors, Opioid, delta; Stereoisomerism; Structure-Activity Relationship; Thermodynamics; Vas Deferens | 1994 |
Development of a model for the delta-opioid receptor pharmacophore: 3. Comparison of the cyclic tetrapeptide, Tyr-c[D-Cys-Phe-D-Pen]OH with other conformationally constrained delta-receptor selective ligands.
Topics: Amino Acid Sequence; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ligands; Models, Chemical; Models, Molecular; Molecular Sequence Data; Oligopeptides; Peptides, Cyclic; Protein Conformation; Receptors, Opioid, delta | 1996 |
Development of a model for the delta-opioid receptor pharmacophore. 4. Residue 3 dehydrophenylalanine analogues of Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13) confirm required gauche orientation of aromatic side chain.
Topics: Amino Acid Sequence; Animals; Binding Sites; Enkephalins; Guinea Pigs; In Vitro Techniques; Ligands; Models, Molecular; Molecular Sequence Data; Protein Conformation; Receptors, Opioid, delta; Thermodynamics | 1996 |
Comparison of cyclic delta-opioid peptides with non-peptide delta-agonist spiroindanyloxymorphone (SIOM) using the message-address concept: a molecular modeling study.
Topics: Drug Design; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Naltrexone; Narcotic Antagonists; Oxymorphone; Peptides, Cyclic; Protein Binding; Protein Conformation; Receptors, Opioid, delta; Spiro Compounds; Structure-Activity Relationship | 1996 |
Development and validation of opioid ligand-receptor interaction models: the structural basis of mu vs delta selectivity.
Topics: Binding Sites; Binding, Competitive; Enkephalins; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Peptides, Cyclic; Phenylalanine; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Substrate Specificity | 2002 |
Peptidic delta opioid receptor agonists produce antidepressant-like effects in the forced swim test and regulate BDNF mRNA expression in rats.
Topics: Adamantane; Animals; Antidepressive Agents; Autoradiography; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Expression Regulation; Immobility Response, Tonic; In Situ Hybridization; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; RNA, Messenger; Swimming; Tetrahydroisoquinolines | 2006 |