enkephalin, leucine has been researched along with guanylyl imidodiphosphate in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (61.29) | 18.7374 |
| 1990's | 24 (38.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blume, AJ | 2 |
| Blume, AJ; Boone, G; Lichtshtein, D | 1 |
| Barnard, EA; Richardson, A; Simon, J | 1 |
| Dziedzicka, M; Lasoń, W; Przewłocka, B; Przewłocki, R | 1 |
| Liu, YF; Quirion, R | 1 |
| Gibo, DM; McLaughlin, PJ; Zagon, IS | 1 |
| Barg, J; Belcheva, M; Bem, WT; Coscia, CJ; Yeung, SJ | 1 |
| Birch, PJ; Hayes, AG; Lawrence, AJ; Rogers, H; Traynor, JR | 1 |
| Barnard, EA; Demoliou-Mason, CD; Hanley, MR; Wong, YH | 1 |
| Coscia, CJ; Szücs, M | 1 |
| McKenzie, FR; Milligan, G | 1 |
| Fedynyshyn, JP; Lee, NM | 1 |
| Costa, T; Ott, S | 1 |
| Bidlack, JM; Selley, DE | 1 |
| Kamikubo, K; Miura, K; Murase, H; Murayama, M; Tsurumi, K; Yasuda, K | 1 |
| Kamikubo, K; Matsuda, M; Miura, K; Murase, H; Murayama, M | 1 |
| Childers, SR | 1 |
| Kamikubo, K; Miura, K; Murase, H; Niwa, M; Nozaki, M; Tsurumi, K | 2 |
| Bolger, GT; Marcus, KA; Skolnick, P; Thibou, R; Weissman, BA | 1 |
| Keldysh, PL; Kurochkin, IN; Skliankina, OA; Varfolomeev, SD; Zaĭtsev, SV | 1 |
| Barnard, EA; Demoliou-Mason, CD; Wong, YH | 1 |
| Coscia, CJ; Petta, DE; Spain, JW | 1 |
| Cros, J; Francés, B; Meunier, JC; Porthé, G; Verrier, B | 1 |
| Farges, RC; Meunier, JC; Moisand, C; Puget, A | 1 |
| Fujioka, T; Inoue, F; Kuriyama, M; Sumita, S | 1 |
| Frances, B; Meunier, JC; Moisand, C | 1 |
| Barnard, EA; Demoliou-Mason, CD | 2 |
| Bidlack, JM; Selley, DE; Tyler, CB | 1 |
| Hom, DS; Law, PY; Loh, HH | 1 |
| Richards, ML; Sadée, W; Yu, VC | 1 |
| Costa, T; Herz, A; Vachon, L | 1 |
| Coscia, CJ; Moudy, AM; Oetting, GM; Spain, JW; Szücs, M | 1 |
| Blanchard, SG; Chang, KJ; Hong, JS; Lee, PH; Pugh, WW | 1 |
| Coscia, CJ; Spain, JW | 1 |
| Barg, J; Levy, R; Simantov, R | 1 |
| Mizuno, S; Mori, A; Ogawa, N | 1 |
| Bennett, DB; Coscia, CJ; Spain, JW | 1 |
| Griffin, MT; Law, PY; Loh, HH | 1 |
| Gintzler, AR; Zukin, RS | 1 |
| Hamprecht, B; Propst, F | 1 |
| Coscia, CJ; Laskowski, MB; Roth, BL | 1 |
| Dawson, G; Lockney, MW; Scheideler, MA | 1 |
| Cermak, D; Dawson, G; Ellory, JC; McLawhon, RW | 1 |
| Koehler, JE; Law, PY; Loh, HH; Wu, J | 1 |
| Adachi, T; Ambo, A; Sasaki, Y | 1 |
| Barnard, EA; Benyhe, S; Borsodi, A; Simon, J; Wollemann, M | 1 |
| Iwai, T; Luay, AE; Niwa, M; Nozaki, M; Tsurumi, K | 1 |
| Fang, L; Haaseth, RC; Horvath, R; Hruby, VJ; Knapp, RJ; Matsunaga, TO; Porreca, F; Yamamura, HI | 1 |
| Law, PY; Lee, CR; Loh, HH; Tao, PL | 1 |
| Ishige, K; Ito, Y; Makimura, M; Murakoshi, Y | 1 |
| de Costa, BR; Kayakiri, H; Ni, Q; Partilla, JS; Rice, KC; Rothman, RB; Xu, H | 1 |
| Chang, LR; Lee, CR; Lue, WM; Tao, PL | 1 |
| Chien, CC; Pasternak, GW; Ryan-Moro, J; Standifer, KM | 1 |
| Bertin, B; Capeyrou, R; Corbani, M; Emorine, LJ; Lepage, JF; Riond, J | 1 |
| Carr, C; Georgoussi, Z; Megaritis, G; Merkouris, M; Milligan, G; Mullaney, I; Zioudrou, C | 1 |
| Avram, D; Bouvier, C; Hettinger, B; Leid, M; Murray, TF; Peterson, VJ; Soderstrom, K | 1 |
| Brown, GP; Pasternak, GW | 1 |
| Borsodi, A; Nguyen, TM; Otvös, F; Schiller, PW; Spetea, M; Tóth, G; Vogel, Z | 1 |
| Emorine, LJ; Exner, T; Gaibelet, G; Liaubet, L; Masson, JM; Meilhoc, E; Nürnberg, B; Riond, J; Saves, I | 1 |
62 other study(ies) available for enkephalin, leucine and guanylyl imidodiphosphate
| Article | Year |
|---|---|
Interaction of ligands with the opiate receptors of brain membranes: regulation by ions and nucleotides.
Topics: Animals; Brain; Enkephalins; Etorphine; Guanylyl Imidodiphosphate; Ligands; Male; Manganese; Morphine; Morphine Derivatives; Naltrexone; Rats; Receptors, Opioid; Ribonucleotides; Sodium | 1978 |
Opiate binding to membrane preparations of neuroblastoma x glioma hybrid cells NG108-15: effects of ions and nucleotides.
Topics: Cell Membrane; Cells, Cultured; Enkephalins; Etorphine; Glioma; Guanylyl Imidodiphosphate; Hybrid Cells; Magnesium; Manganese; Naloxone; Neuroblastoma; Nucleotides; Receptors, Opioid; Sodium | 1978 |
Regulation of the neuroblastoma x glioma hybrid opiate receptors by Na+ and guanine nucleotides.
Topics: Animals; Binding, Competitive; Cell Line; Enkephalins; Glioma; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Neuroblastoma; Receptors, Opioid; Sodium | 1979 |
Protection by opioid ligands against modification of the opioid receptor by a carbodiimide.
Topics: Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Brain Chemistry; Carbodiimides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Pyrrolidines; Receptors, Opioid | 1992 |
Differential effects of opioid receptor agonists on nociception and cAMP level in the spinal cord of monoarthritic rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Arthritis; Benzeneacetamides; Colforsin; Cyclic AMP; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanylyl Imidodiphosphate; Injections, Spinal; Male; Morphine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord | 1992 |
Modulatory role of glutathione on mu-opioid, substance P/neurokinin-1, and kainic acid receptor binding sites.
Topics: Animals; Binding Sites; Cholic Acids; Detergents; Dithiothreitol; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glutathione; Guanylyl Imidodiphosphate; Kainic Acid; Receptors, Kainic Acid; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, mu; Solubility; Substance P; Swine | 1992 |
Zeta (zeta), a growth-related opioid receptor in developing rat cerebellum: identification and characterization.
Topics: Animals; Animals, Newborn; Binding, Competitive; Cations; Cerebellum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Female; Guanylyl Imidodiphosphate; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Subcellular Fractions; Temperature; Trypsin | 1991 |
Age-dependent changes in the subcellular distribution of rat brain mu-opioid receptors and GTP binding regulatory proteins.
Topics: Aging; Animals; Animals, Newborn; Blotting, Western; Cell Fractionation; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Male; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Subcellular Fractions | 1991 |
The selectivity of the opioid antagonist, naltrindole, for delta-opioid receptors.
Topics: Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; In Vitro Techniques; Indoles; Male; Mice; Mice, Inbred Strains; Morphinans; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium; Vas Deferens | 1990 |
Agonist-selective protection of the opioid receptor-coupled G proteins from inactivation by 5'-p-fluorosulphonylbenzoyl guanosine.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Brain; Cell Membrane; Dithiothreitol; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; GTP-Binding Proteins; Guanosine; Guanylyl Imidodiphosphate; Iodoacetamide; Kinetics; Molecular Sequence Data; Naloxone; Rats; Receptors, Opioid | 1990 |
Evidence for delta-opioid binding and GTP-regulatory proteins in 5-day-old rat brain membranes.
Topics: Animals; Animals, Newborn; Binding, Competitive; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; Membranes; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Software | 1990 |
Delta-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Base Sequence; Cell Line; DNA, Neoplasm; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; GTP Phosphohydrolases; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hybrid Cells; Immune Sera; Kinetics; Mice; Molecular Sequence Data; NAD; Neuroblastoma; Oligonucleotide Probes; Pertussis Toxin; Rats; Receptors, Opioid; Receptors, Opioid, delta; RNA, Neoplasm; Signal Transduction; Virulence Factors, Bordetella | 1990 |
Mu-type opioid receptors in rat periaqueductal gray-enriched P2 membrane are coupled to guanine nucleotide binding proteins.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Male; Periaqueductal Gray; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Signal Transduction | 1989 |
Enzymatic degradation of GTP and its "stable" analogues produce apparent isomerization of opioid receptors.
Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Thionucleotides | 1989 |
Guanine nucleotide regulation of [125I]beta-endorphin binding to NG108-15 and SK-N-SH cell membranes: specific cation requirements.
Topics: beta-Endorphin; Cations; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Glioma; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Hybrid Cells; Neuroblastoma; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride; Tumor Cells, Cultured | 1989 |
[Characterization of adrenal medullary opioid receptors. II. Coupling of adrenal medullary opioid receptors to GTP binding proteins].
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenal Medulla; Animals; Cattle; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Levorphanol; Pertussis Toxin; Receptors, Opioid; Virulence Factors, Bordetella | 1987 |
Evidence for disulfide bonds in membrane-bound and solubilized opioid receptors.
Topics: Adrenal Medulla; Animals; Cattle; Cell Membrane; Chromatography, Gel; Digitonin; Diprenorphine; Disulfides; Dithiothreitol; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanylyl Imidodiphosphate; Hydrogen Peroxide; Kinetics; Mercaptoethanol; Molecular Weight; Receptors, Opioid; Solubility | 1988 |
Opiate-inhibited adenylate cyclase in rat brain membranes depleted of Gs-stimulated adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Brain; Cell Membrane; Cholera Toxin; Colforsin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Male; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Fluoride; Virulence Factors, Bordetella | 1988 |
Adrenal medullary opioid receptors are linked to GTP-binding proteins, pertussis toxin substrates.
Topics: Adenylate Cyclase Toxin; Adrenal Medulla; Animals; Cattle; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Pertussis Toxin; Receptors, Opioid; Virulence Factors, Bordetella | 1986 |
Enhancement of [3H]DAGO1 binding to rat brain by low concentrations of monovalent cations.
Topics: Animals; Batrachotoxins; Benzomorphans; Brain Chemistry; Cations, Monovalent; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Guanine Nucleotides; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Naloxone; Rats; Receptors, Opioid; Temperature | 1987 |
[A kinetic model of the interaction of stable GTP analogs with a system of opioid receptors].
Topics: Animals; Binding, Competitive; Brain; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Ligands; Male; Models, Biological; Morphine; Naloxone; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid | 1988 |
ADP-ribosylation with pertussis toxin modulates the GTP-sensitive opioid ligand binding in digitonin-soluble extracts of rat brain membranes.
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cell Membrane; Digitonin; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Receptors, Opioid; Sodium; Solubility; Virulence Factors, Bordetella | 1988 |
Binding kinetics of delta opioid receptors differ for microsomal and synaptic sites.
Topics: Animals; Cattle; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hippocampus; In Vitro Techniques; Kinetics; Magnesium; Manganese; Microsomes; Receptors, Opioid; Receptors, Opioid, delta; Sodium; Synapses | 1988 |
The kappa-opioid receptor from human placenta: hydrodynamic characteristics and evidence for its association with a G protein.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Binding, Competitive; Centrifugation, Density Gradient; Chromatography, Gel; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Female; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Microvilli; Oligopeptides; Placenta; Pregnancy; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Sodium Chloride | 1988 |
Opioid receptor types in the brain of the Afghan pika (Ochotona rufescens), a species which is naturally tolerant to morphine.
Topics: Animals; Binding, Competitive; Brain Chemistry; Diprenorphine; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanylyl Imidodiphosphate; Lagomorpha; Membranes; Morphine; Oligopeptides; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium | 1988 |
Reconstitution of partially purified opioid receptors with a GTP-binding protein.
Topics: Animals; Binding, Competitive; Brain; Cattle; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Rats; Receptors, Opioid | 1988 |
Na+ ions and Gpp(NH)p selectively inhibit agonist interactions at mu- and kappa-opioid receptor sites in rabbit and guinea-pig cerebellum membranes.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzomorphans; Binding, Competitive; Cerebellum; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium | 1985 |
Characterization of opioid receptor subtypes in solution.
Topics: Animals; Brain; Cations; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Dihydromorphine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Guanylyl Imidodiphosphate; Iodoacetamide; Kinetics; Magnesium; Naloxone; Rats; Receptors, Opioid; Sodium; Solutions | 1986 |
Guanine nucleotide regulation of [125I]beta-endorphin binding to rat brain membranes: monovalent cation requirement.
Topics: Animals; beta-Endorphin; Brain; Cations, Monovalent; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Lithium; Male; Phenazocine; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride | 1988 |
Multiple affinity states of opiate receptor in neuroblastoma x glioma NG108-15 hybrid cells. Opiate agonist association rate is a function of receptor occupancy.
Topics: Animals; Binding, Competitive; Cell Line; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Magnesium; Neuroblastoma; Receptors, Opioid; Sodium | 1985 |
A human neuroblastoma cell line expresses mu and delta opioid receptor sites.
Topics: Bone Neoplasms; Cell Line; Child, Preschool; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Female; Guanylyl Imidodiphosphate; Humans; Kinetics; Naloxone; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride | 1986 |
Distinct subtypes of the opioid receptor with allosteric interactions in brain membranes.
Topics: Allosteric Site; Animals; Brain; Cations; Cell Membrane; Dihydromorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium | 1986 |
Differential sensitivity of basal and opioid-stimulated low Km GTPase to guanine nucleotide analogs.
Topics: Animals; Cell Line; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP Phosphohydrolases; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Phosphoric Monoester Hydrolases; Structure-Activity Relationship; Thionucleotides | 1986 |
Guanine nucleotide and cation regulation of mu, delta, and kappa opioid receptor binding: evidence for differential postnatal development in rat brain.
Topics: Animals; Brain; Cations; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Manganese; Manganese Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Chloride | 1987 |
Coupling of adrenal medullary opioid receptors to islet-activating protein-sensitive GTP-binding proteins.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adrenal Medulla; Animals; Cattle; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Pertussis Toxin; Receptors, Opioid; Virulence Factors, Bordetella | 1987 |
Characterization of the binding of a morphine (mu) receptor-specific ligand: Tyr-Pro-NMePhe-D-Pro-NH2, [3H]-PL17.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Guanylyl Imidodiphosphate; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Substrate Specificity; Time Factors | 1987 |
Multiple interconvertible affinity states for the delta opioid agonist-receptor complex.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylmaleimide; Guanylyl Imidodiphosphate; Hippocampus; Kinetics; Morphine; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Synaptic Membranes | 1987 |
Up-regulation of opiate receptors by opiate antagonists in neuroblastoma-glioma cell culture: the possibility of interaction with guanosine triphosphate-binding proteins.
Topics: Animals; Cells, Cultured; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Naloxone; Neuroblastoma; Rats; Receptors, Opioid; Receptors, Opioid, delta | 1984 |
Interaction of enkephalin with opioid receptors of brain membranes: regulation by essential transition metals, guanine nucleotides and temperature.
Topics: Animals; Copper; Enkephalins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium; Temperature; Zinc | 1984 |
Gpp(NH)p promotes the formation of a low affinity state for the delta opioid agonist-receptor complex.
Topics: Animals; Cattle; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; In Vitro Techniques; Kinetics; Receptors, Opioid; Receptors, Opioid, delta; Synaptic Membranes | 1984 |
Mechanisms of multiple cellular adaptation processes in clonal cell lines during chronic opiate treatment.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Cell Line; Clone Cells; Cytosol; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Glioma; Guanylyl Imidodiphosphate; Lanthanum; Mice; Naloxone; Narcotics; Neuroblastoma; Rats; Receptors, Opioid; Sodium; Time Factors | 1984 |
Guanyl nucleotide interactions with opiate receptors in guinea pig brain and ileum.
Topics: Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Ileum; Kinetics; Male; Morphine Derivatives; Organ Specificity; Receptors, Opioid | 1980 |
Opioids, noradrenaline and GTP analogs inhibit cholera toxin activated adenylate cyclase in neuroblastoma x glioma hybrid cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Clone Cells; Diphosphonates; Endorphins; Enkephalin, Methionine; Enkephalins; Glioma; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Mice; Morphine; Neuroblastoma; Norepinephrine; Rats | 1981 |
Evidence for distinct subcellular sites of opiate receptors. Demonstration of opiate receptors in smooth microsomal fractions isolated from rat brain.
Topics: Animals; Binding, Competitive; Brain; Cell Fractionation; Enkephalin, Methionine; Enkephalins; Guanylyl Imidodiphosphate; Kinetics; Microscopy, Electron; Microsomes; Naloxone; Rats; Receptors, Opioid; Subcellular Fractions | 1981 |
Cell cycle-dependent expression of specific opiate binding with variable coupling to adenylate cyclase in a neurotumor hybrid cell line NG108-15.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Cycle; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanylyl Imidodiphosphate; Hybrid Cells; Mice; Neoplasms, Nerve Tissue; Prostaglandins E; Rats; Receptors, Opioid | 1983 |
Glycosylation-dependent regulation of opiate (enkephalin) receptors in neurotumor cells.
Topics: Animals; Carbohydrate Metabolism; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Mice; Neoplasms, Nerve Tissue; Rats; Receptors, Opioid; Tunicamycin | 1983 |
Demonstration and characterization of opiate inhibition of the striatal adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Animals; Chlorides; Corpus Striatum; Endorphins; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Manganese; Manganese Compounds; Naloxone; Rats; Sodium Chloride; Sodium Fluoride; Stereoisomerism | 1981 |
Synthesis and opioid activities of [D-Leu-8]Dynorphin(1-8) analogs containing a reduced peptide bond, psi(CH2-NH).
Topics: Amino Acid Sequence; Analgesics; Animals; Binding, Competitive; Cerebellum; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Ileum; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Opioid Peptides; Receptors, Opioid | 1995 |
[3H]dynorphin1-8 binding sites in frog (Rana esculenta) brain membranes.
Topics: Amino Acid Sequence; Animals; Brain; Cell Membrane; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Naloxone; Peptide Fragments; Rana esculenta; Receptors, Opioid; Sodium Chloride; Tritium | 1994 |
Characterization of opioid receptors in the Mongolian gerbil cerebellum.
Topics: Animals; Autoradiography; Benzeneacetamides; Binding Sites; Binding, Competitive; Cerebellum; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gerbillinae; Guanylyl Imidodiphosphate; In Vitro Techniques; Narcotics; Pyrrolidines; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, mu | 1994 |
Characterization of [3H]naltrindole binding to delta opioid receptors in mouse brain and mouse vas deferens: evidence for delta opioid receptor heterogeneity.
Topics: Animals; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Vas Deferens | 1994 |
The interaction of the mu-opioid receptor and G protein is altered after chronic morphine treatment in rats.
Topics: Amino Acid Sequence; Analgesics; Animals; Cell Membrane; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Male; Mesencephalon; Molecular Sequence Data; Morphine; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stimulation, Chemical | 1993 |
Inhibitory effects of NaCl and guanyl-5'yl-imidodiphosphate (GppNHp) on [3H]naloxone binding to kappa-opioid receptors in guinea pig cerebellum.
Topics: Animals; Benzeneacetamides; Binding Sites; Cerebellum; Cerebral Cortex; Corpus Striatum; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylmaleimide; Guanylyl Imidodiphosphate; Guinea Pigs; Male; Naloxone; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Sodium Chloride | 1993 |
Opioid peptide receptor studies. 3. Interaction of opioid peptides and other drugs with four subtypes of the kappa 2 receptor in guinea pig brain.
Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Morphinans; Opioid Peptides; Protein Precursors; Rats; Receptors, Opioid, kappa; Swine | 1995 |
Alteration of the interaction of mu-opioid receptor and G protein after chronic PL017 treatment in rats.
Topics: Analgesics; Animals; Drug Tolerance; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; In Vitro Techniques; Kinetics; Male; Mesencephalon; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1995 |
Sigma binding in a human neuroblastoma cell line.
Topics: Adenylyl Cyclases; Analgesics; Analysis of Variance; Animals; Binding, Competitive; Brain; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Haloperidol; Humans; Kinetics; Morphine; Naloxone; Neuroblastoma; Pentazocine; Phosphatidylinositols; Receptors, Opioid; Receptors, sigma; Trypsin; Tumor Cells, Cultured | 1996 |
Agonist-induced signaling and trafficking of the mu-opioid receptor: role of serine and threonine residues in the third cytoplasmic loop and C-terminal domain.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Etorphine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Morphine; Mutagenesis, Site-Directed; Receptors, Opioid, mu; Serine; Signal Transduction; Threonine | 1997 |
Selective interactions of mu-opioid receptors with pertussis toxin-sensitive G proteins: involvement of the third intracellular loop and the c-terminal tail in coupling.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Cholera Toxin; DNA, Complementary; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fibroblasts; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanylyl Imidodiphosphate; Molecular Sequence Data; Oligopeptides; Pertussis Toxin; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Rats; Receptors, Opioid, mu; Virulence Factors, Bordetella | 1997 |
Catecholaminergic CATH.a cells express predominantly delta-opioid receptors.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Cell Line; Diprenorphine; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanylyl Imidodiphosphate; In Vitro Techniques; Mice; Narcotic Antagonists; Neurons; Polymerase Chain Reaction; Radioligand Assay; Receptors, Opioid, delta; Receptors, sigma; Signal Transduction | 1998 |
3H-naloxone benzoylhydrazone binding in MOR-1-transfected Chinese hamster ovary cells: evidence for G-protein-dependent antagonist binding.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; CHO Cells; Cholera Toxin; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Naloxone; Narcotic Antagonists; Pertussis Toxin; Receptors, Opioid, mu; Transfection; Virulence Factors, Bordetella | 1998 |
Interaction of agonist peptide [3H]Tyr-D-Ala-Phe-Phe-NH2 with mu-opioid receptor in rat brain and CHO-mu/1 cell line.
Topics: Animals; Brain; CHO Cells; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanylyl Imidodiphosphate; Ligands; Oligopeptides; Rats; Receptors, Opioid, mu; Tritium | 1998 |
Nonselective coupling of the human mu-opioid receptor to multiple inhibitory G-protein isoforms.
Topics: Binding Sites; Binding, Competitive; Buprenorphine; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Gene Expression; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Protein Binding; Protein Isoforms; Receptors, Opioid, mu; Recombinant Proteins; Saccharomyces cerevisiae; Spheroplasts; Transformation, Genetic | 1999 |