enkephalin, leucine and guanosine triphosphate

enkephalin, leucine has been researched along with guanosine triphosphate in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199042 (71.19)18.7374
1990's17 (28.81)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blume, AJ; Boone, G; Lichtshtein, D2
Kuhar, MJ; Young, WS1
Childers, SR; Nijssen, PC; Sexton, T1
Carter, BD; Medzihradsky, F1
Olianas, MC; Onali, P1
Kim, DC; Krumins, SA; Larson, AA1
Kuhar, MJ; Wamsley, JK; Zarbin, MA1
Illes, P; Regenold, JT1
Costa, M; North, RA; Schimerlik, M; Tatsumi, H1
Krekhnov, BV; Kurochkin, IN; Skliankina, OA; Varfolomeev, SD; Varfolomeeva, AD; Zaĭtsev, SV1
Costa, T; Herz, A; Ott, S1
Costa, T; Ott, S1
Clark, MJ; Medzihradsky, F; Nordby, GL1
Bidlack, JM; Selley, DE1
Bowen, WD; Herkenham, M; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB1
Kamikubo, K; Miura, K; Murase, H; Niwa, M; Nozaki, M; Tsurumi, K1
Keldysh, PL; Kurochkin, IN; Skliankina, OA; Varfolomeev, SD; Zaĭtsev, SV1
Barnard, EA; Demoliou-Mason, CD; Wong, YH1
Duman, RS; Nestler, EJ; Tallman, JF1
Frances, B; Meunier, JC; Moisand, C1
Bidlack, JM; Selley, DE; Tyler, CB1
Brown, SR; Cox, BM; Werling, LL; Zarr, GD1
Hirobe, M; Konno, F; Sato, Y; Takayanagi, I; Togashi, K1
Grandt, R; Greiner, C; Jakobs, KH; Zubin, P1
Costa, T; Herz, A; Vachon, L1
Coscia, CJ; Moudy, AM; Oetting, GM; Spain, JW; Szücs, M1
Chung, CT; Hoffman, PL; Tabakoff, B1
Barg, J; Levy, R; Simantov, R1
Mizuno, S; Mori, A; Ogawa, N1
Bennett, DB; Coscia, CJ; Spain, JW1
Ganten, D; Lang, RE; McDonald, WJ; Notter, M1
Klee, WA; Koski, G1
Coy, DH; Kastin, AJ; Luciano, MG; Zadina, JE1
Franklin, PH; Hoss, W1
Makman, MH; Walczak, S; Zukin, RS1
Gintzler, AR; Zukin, RS1
Herkenham, MA; Kent, JL; Pert, A; Pert, CB; Taylor, DP1
Chang, KJ; Cuatrecasas, P; Hazum, E1
Hamprecht, B; Propst, F1
Chang, JK; Chang, KJ; Cuatrecasas, P; Hazum, E; Lillian, A1
Chang, KJ; Cuatrecasas, P; Hazum, E; Killian, A1
Bowen, WD; Gentleman, S; Herkenham, M; Pert, CB1
Cooper, DM; Gill, DL; Londos, C; Rodbell, M1
Koehler, JE; Law, PY; Loh, HH1
Fitz-Syage, ML; Gardner, EL; Gintzler, AR; Sugarman, JR; Zukin, RS; Zukin, SR1
Costa, T; Krumins, SA; Munson, PJ; Rodbard, D; Shimohigashi, Y1
Costa, T; Krumins, S; Rodbard, D; Shimohigashi, Y1
Cermak, D; Dawson, G; Ellory, JC; McLawhon, RW1
Koehler, JE; Law, PY; Loh, HH; Wu, J1
Medzihradsky, F; Yabaluri, N1
Bell, GI; Kong, H; Moe, ST; Portoghese, PS; Raynor, K; Reisine, T; Yasuda, K1
Breivogel, CS; Childers, SR; Selley, DE1
Laugwitz, KL; Offermanns, S; Schultz, G; Spicher, K1
Fukushima, N; Hayashi, C; Katayama, T; Misu, Y; Ueda, H1
Ho, MK; Wong, YH1
Albrecht, E; Baeger, I; Berger, H; Fechner, K; Heinrich, N; Lorenz, D; Samovilova, N1
Albrecht, E; Baeger, I; Berger, H; Oswald, S; Samovilova, NN1
Allouche, S; Hasbi, A; Homburger, V; Jauzac, P; Polastron, J1

Other Studies

59 other study(ies) available for enkephalin, leucine and guanosine triphosphate

ArticleYear
Regulation of the neuroblastoma x glioma hybrid opiate receptors by Na+ and guanine nucleotides.
    Advances in experimental medicine and biology, 1979, Volume: 116

    Topics: Animals; Binding, Competitive; Cell Line; Enkephalins; Glioma; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Neuroblastoma; Receptors, Opioid; Sodium

1979
A new method for receptor autoradiography: [3H]opioid receptors in rat brain.
    Brain research, 1979, Dec-28, Volume: 179, Issue:2

    Topics: Animals; Autoradiography; Brain; Corpus Striatum; Dihydromorphine; Diprenorphine; Enkephalins; Frontal Lobe; Guanosine Triphosphate; Histological Techniques; Male; Rats; Receptors, Opioid; Sodium; Tritium

1979
Coupling of opiate receptors to adenylate cyclase: requirement for Na+ and GTP.
    Proceedings of the National Academy of Sciences of the United States of America, 1979, Volume: 76, Issue:11

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cations, Divalent; Cations, Monovalent; Cell Line; Enkephalins; Guanosine Triphosphate; Membranes; Mice; Neurons; Prostaglandins E; Receptors, Opioid; Sodium

1979
Opioid-inhibited adenylyl cyclase in rat brain membranes: lack of correlation with high-affinity opioid receptor binding sites.
    Journal of neurochemistry, 1992, Volume: 59, Issue:6

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Cell Membrane; Colforsin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Male; Naloxone; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium; Sodium Chloride; Sodium Fluoride

1992
Opioid signal transduction in intact and fragmented SH-SY5Y neural cells.
    Journal of neurochemistry, 1992, Volume: 58, Issue:5

    Topics: Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine Triphosphate; Humans; Intracellular Membranes; Ligands; Nervous System Neoplasms; Signal Transduction; Tumor Cells, Cultured

1992
Naturally occurring opioid receptor agonists stimulate adenylate cyclase activity in rat olfactory bulb.
    Molecular pharmacology, 1991, Volume: 39, Issue:4

    Topics: Adenylyl Cyclases; Alkaloids; Animals; beta-Endorphin; Calcium; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enzyme Activation; Guanosine Triphosphate; Intracellular Fluid; Kinetics; Male; Naloxone; Olfactory Bulb; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Opioid; Staurosporine; Stimulation, Chemical

1991
Substance P modulation of [3H]DAGO binding in the brain of Swiss-Webster and CXBK (mu opioid receptor deficient) mice.
    Progress in clinical and biological research, 1990, Volume: 328

    Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Mice; Mice, Mutant Strains; Receptors, Opioid; Receptors, Opioid, mu; Substance P

1990
Anterograde transport of opioid receptors in rat vagus nerves and dorsal roots of spinal nerves: pharmacology and sensitivity to sodium and guanine nucleotides.
    Experimental brain research, 1990, Volume: 81, Issue:2

    Topics: Animals; Axonal Transport; Colchicine; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guanosine Triphosphate; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride; Spinal Nerve Roots; Vagus Nerve

1990
Interaction between neuropeptide Y and noradrenaline on central catecholamine neurons.
    Nature, 1990, Mar-01, Volume: 344, Issue:6261

    Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Locus Coeruleus; Neuropeptide Y; Norepinephrine; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, mu; Thionucleotides; Yohimbine

1990
Potassium conductance increased by noradrenaline, opioids, somatostatin, and G-proteins: whole-cell recording from guinea pig submucous neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Dialysis; Electric Conductivity; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Narcotics; Neurons; Norepinephrine; Pertussis Toxin; Potassium; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, delta; Somatostatin; Submucous Plexus; Thionucleotides; Time Factors; Virulence Factors, Bordetella

1990
[Kinetic characteristics of the effect of GTP on properties of opioid receptors].
    Biokhimiia (Moscow, Russia), 1990, Volume: 55, Issue:6

    Topics: Adenine Nucleotides; Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Kinetics; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1990
Opioid receptors of neuroblastoma cells are in two domains of the plasma membrane that differ in content of G proteins.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Fractionation; Cell Membrane; Centrifugation; Diprenorphine; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Neuroblastoma; Pertussis Toxin; Receptors, Opioid; Tumor Cells, Cultured; Virulence Factors, Bordetella

1989
Enzymatic degradation of GTP and its "stable" analogues produce apparent isomerization of opioid receptors.
    Journal of receptor research, 1989, Volume: 9, Issue:1

    Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Thionucleotides

1989
Relationship between opioid-receptor occupancy and stimulation of low-Km GTPase in brain membranes.
    Journal of neurochemistry, 1989, Volume: 52, Issue:4

    Topics: Animals; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP Phosphohydrolases; Guanosine Triphosphate; Magnesium; Membranes; Naltrexone; Oligopeptides; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium

1989
Guanine nucleotide regulation of [125I]beta-endorphin binding to NG108-15 and SK-N-SH cell membranes: specific cation requirements.
    Brain research, 1989, Jul-24, Volume: 493, Issue:1

    Topics: beta-Endorphin; Cations; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Glioma; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Hybrid Cells; Neuroblastoma; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride; Tumor Cells, Cultured

1989
A quantitative study of [3H]D-Ala2-D-Leu5-enkephalin binding to rat brain membranes. Evidence that oxymorphone is a noncompetitive inhibitor of the lower affinity delta-binding site.
    Molecular pharmacology, 1985, Volume: 27, Issue:3

    Topics: Animals; Autoradiography; Brain; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Hydromorphone; Male; Manganese; Manganese Compounds; Mathematics; Membranes; Oligopeptides; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride

1985
Adrenal medullary opioid receptors are linked to GTP-binding proteins, pertussis toxin substrates.
    NIDA research monograph, 1986, Volume: 75

    Topics: Adenylate Cyclase Toxin; Adrenal Medulla; Animals; Cattle; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Pertussis Toxin; Receptors, Opioid; Virulence Factors, Bordetella

1986
[A kinetic model of the interaction of stable GTP analogs with a system of opioid receptors].
    Biokhimiia (Moscow, Russia), 1988, Volume: 53, Issue:2

    Topics: Animals; Binding, Competitive; Brain; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Ligands; Male; Models, Biological; Morphine; Naloxone; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid

1988
ADP-ribosylation with pertussis toxin modulates the GTP-sensitive opioid ligand binding in digitonin-soluble extracts of rat brain membranes.
    Journal of neurochemistry, 1988, Volume: 51, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cell Membrane; Digitonin; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Receptors, Opioid; Sodium; Solubility; Virulence Factors, Bordetella

1988
Acute and chronic opiate-regulation of adenylate cyclase in brain: specific effects in locus coeruleus.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Locus Coeruleus; Male; Morphine; Narcotics; Neurons; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Time Factors; Virulence Factors, Bordetella

1988
Na+ ions and Gpp(NH)p selectively inhibit agonist interactions at mu- and kappa-opioid receptor sites in rabbit and guinea-pig cerebellum membranes.
    European journal of pharmacology, 1985, Nov-05, Volume: 117, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzomorphans; Binding, Competitive; Cerebellum; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium

1985
Guanine nucleotide regulation of [125I]beta-endorphin binding to rat brain membranes: monovalent cation requirement.
    Journal of neurochemistry, 1988, Volume: 50, Issue:6

    Topics: Animals; beta-Endorphin; Brain; Cations, Monovalent; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Lithium; Male; Phenazocine; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride

1988
Opioid binding to rat and guinea-pig neural membranes in the presence of physiological cations at 37 degrees C.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:3

    Topics: Animals; Brain; Cations; Cyclazocine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Male; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Temperature; Tritium

1985
Interactions of codeine-7,8-oxide (codeine-epoxide), as a new metabolite of codeine, with multiple opiate receptors.
    General pharmacology, 1985, Volume: 16, Issue:4

    Topics: Animals; Brain; Cell Membrane; Codeine; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guanosine Triphosphate; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride

1985
Bradykinin stimulates GTP hydrolysis in NG108-15 membranes by a high-affinity, pertussis toxin-insensitive GTPase.
    FEBS letters, 1986, Feb-17, Volume: 196, Issue:2

    Topics: Bradykinin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Hybrid Cells; Hydrolysis; Membranes; Neuroblastoma; Pertussis Toxin; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Virulence Factors, Bordetella

1986
Differential sensitivity of basal and opioid-stimulated low Km GTPase to guanine nucleotide analogs.
    Journal of neurochemistry, 1986, Volume: 47, Issue:5

    Topics: Animals; Cell Line; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP Phosphohydrolases; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Phosphoric Monoester Hydrolases; Structure-Activity Relationship; Thionucleotides

1986
Guanine nucleotide and cation regulation of mu, delta, and kappa opioid receptor binding: evidence for differential postnatal development in rat brain.
    Journal of neurochemistry, 1987, Volume: 48, Issue:4

    Topics: Animals; Brain; Cations; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Manganese; Manganese Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Chloride

1987
Effects of ethanol, temperature, and endogenous regulatory factors on the characteristics of striatal opiate receptors.
    Journal of neurochemistry, 1984, Volume: 43, Issue:4

    Topics: Animals; Corpus Striatum; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethanol; Guanosine Triphosphate; Male; Mice; Mice, Inbred C57BL; Receptors, Opioid; Sodium; Temperature

1984
Up-regulation of opiate receptors by opiate antagonists in neuroblastoma-glioma cell culture: the possibility of interaction with guanosine triphosphate-binding proteins.
    Neuroscience letters, 1984, Sep-07, Volume: 50, Issue:1-3

    Topics: Animals; Cells, Cultured; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Naloxone; Neuroblastoma; Rats; Receptors, Opioid; Receptors, Opioid, delta

1984
Interaction of enkephalin with opioid receptors of brain membranes: regulation by essential transition metals, guanine nucleotides and temperature.
    Advances in experimental medicine and biology, 1984, Volume: 175

    Topics: Animals; Copper; Enkephalins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium; Temperature; Zinc

1984
Gpp(NH)p promotes the formation of a low affinity state for the delta opioid agonist-receptor complex.
    Neuropeptides, 1984, Volume: 5, Issue:1-3

    Topics: Animals; Cattle; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; In Vitro Techniques; Kinetics; Receptors, Opioid; Receptors, Opioid, delta; Synaptic Membranes

1984
Influence of intracerebroventricular (ICV) GTP-electrolyte infusion on ICV (D-ALA2, D-LEU5) enkephalin (DADL)-induced cardiovascular effects in rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:10-11

    Topics: Animals; Blood Pressure; Chlorides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Heart Rate; Injections, Intraventricular; Male; Manganese; Manganese Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride

1984
Opiates inhibit adenylate cyclase by stimulating GTP hydrolysis.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:7

    Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cell Membrane; Enkephalin, Leucine-2-Alanine; Enkephalins; GTP Phosphohydrolases; Guanosine Triphosphate; Phosphoric Monoester Hydrolases; Rats; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship

1981
Mu and delta opiate receptors in rat brain are affected by GTP but not by MIF-1.
    Brain research bulletin, 1981, Volume: 7, Issue:6

    Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanosine Triphosphate; Male; MSH Release-Inhibiting Hormone; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium; Temperature

1981
Opiates stimulate low Km GTPase in brain.
    Journal of neurochemistry, 1984, Volume: 43, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Animals; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; GTP Phosphohydrolases; Guanosine Triphosphate; Male; Naloxone; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Tissue Distribution

1984
GTP modulation of opiate receptors in regions of rat brain and possible mechanism of GTP action.
    Brain research, 1980, Mar-17, Volume: 186, Issue:1

    Topics: Amygdala; Animals; Brain; Corpus Striatum; Enkephalins; Frontal Lobe; Guanosine Triphosphate; Hippocampus; Male; Naloxone; Rats; Receptors, Opioid

1980
Guanyl nucleotide interactions with opiate receptors in guinea pig brain and ileum.
    Brain research, 1980, Mar-31, Volume: 186, Issue:2

    Topics: Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Ileum; Kinetics; Male; Morphine Derivatives; Organ Specificity; Receptors, Opioid

1980
Biochemical and autoradiographic evidence for type 1 and type 2 opiate receptors.
    Advances in biochemical psychopharmacology, 1980, Volume: 22

    Topics: Animals; Autoradiography; Brain; Enkephalins; Guanosine Triphosphate; Ligands; Naloxone; Rats; Receptors, Opioid

1980
Possible role of distinct morphine and enkephalin receptors in mediating actins of benzomorphan drugs (putative kappa and sigma agonists).
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:8

    Topics: Animals; Benzomorphans; Brain; Cyclazocine; Diprenorphine; Endorphins; Enkephalins; Ethylketocyclazocine; Guanosine Triphosphate; Morphinans; Morphine; Naloxone; Neuroblastoma; Rats; Receptors, Opioid; Sodium; Synaptic Membranes

1980
Opioids, noradrenaline and GTP analogs inhibit cholera toxin activated adenylate cyclase in neuroblastoma x glioma hybrid cells.
    Journal of neurochemistry, 1981, Volume: 36, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Clone Cells; Diphosphonates; Endorphins; Enkephalin, Methionine; Enkephalins; Glioma; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Mice; Morphine; Neuroblastoma; Norepinephrine; Rats

1981
Morphiceptin (NH4-tyr-pro-phe-pro-COHN2): a potent and specific agonist for morphine (mu) receptors.
    Science (New York, N.Y.), 1981, Apr-03, Volume: 212, Issue:4490

    Topics: Animals; Binding, Competitive; Caseins; Dihydromorphine; Endorphins; Enkephalins; Guanosine Triphosphate; Guinea Pigs; Ileum; Male; Mice; Naloxone; Rats; Receptors, Opioid; Sodium; Vas Deferens

1981
Interactions of ligands with morphine and enkephalin receptors are differentially affected by guanine nucleotide.
    Molecular pharmacology, 1981, Volume: 20, Issue:1

    Topics: Animals; Brain; Cells, Cultured; Diprenorphine; Endorphins; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Magnesium; Naloxone; Neoplasms, Experimental; Neuroblastoma; Rats; Receptors, Opioid; Sodium

1981
Interconverting mu and delta forms of the opiate receptor in rat striatal patches.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:8

    Topics: Adenylyl Cyclases; Animals; Cations, Divalent; Corpus Striatum; Dithiothreitol; Enkephalins; Guanosine Triphosphate; Male; Membrane Fluidity; Morphine; Rats; Receptors, Opioid; Temperature

1981
Opiate receptor-mediated inhibition of adenylate cyclase in rat striatal plasma membranes.
    Journal of neurochemistry, 1982, Volume: 38, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Guanosine Triphosphate; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid

1982
Comparison of opiate inhibition of adenylate cyclase activity in neuroblastoma N18tG2 and neuroblastoma x glioma NG108-15 hybrid cell lines.
    Molecular pharmacology, 1982, Volume: 21, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cyclic AMP; Enkephalins; Glioma; Guanosine Triphosphate; Hybrid Cells; Kinetics; Mice; Narcotics; Neoplasms, Experimental; Neuroblastoma; Rats; Receptors, Opioid

1982
Naltrexone-induced opiate receptor supersensitivity.
    Brain research, 1982, Aug-12, Volume: 245, Issue:2

    Topics: Animals; Brain; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Female; Guanosine Triphosphate; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid

1982
Differential effects of GTP and cations on binding of labeled dimeric and monomeric enkephalins to neuroblastoma-glioma cell delta opiate receptors.
    Biochemical and biophysical research communications, 1982, Sep-16, Volume: 108, Issue:1

    Topics: Animals; Binding, Competitive; Cell Line; Enkephalins; Glioma; Guanosine Triphosphate; Hybrid Cells; Kinetics; Macromolecular Substances; Manganese; Mice; Neuroblastoma; Rats; Receptors, Opioid; Receptors, Opioid, delta; Sodium

1982
Dimeric pentapeptide and tetrapeptide enkephalins: new tools for the study of delta opioid receptors.
    Journal of receptor research, 1983, Volume: 3, Issue:1-2

    Topics: Animals; Cyclic AMP; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, delta

1983
Glycosylation-dependent regulation of opiate (enkephalin) receptors in neurotumor cells.
    Journal of neurochemistry, 1983, Volume: 41, Issue:5

    Topics: Animals; Carbohydrate Metabolism; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Mice; Neoplasms, Nerve Tissue; Rats; Receptors, Opioid; Tunicamycin

1983
Demonstration and characterization of opiate inhibition of the striatal adenylate cyclase.
    Journal of neurochemistry, 1981, Volume: 36, Issue:5

    Topics: Adenylyl Cyclase Inhibitors; Animals; Chlorides; Corpus Striatum; Endorphins; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Manganese; Manganese Compounds; Naloxone; Rats; Sodium Chloride; Sodium Fluoride; Stereoisomerism

1981
Reversible modulation of opioid receptor binding in intact neural cells by endogenous guanosine triphosphate.
    Molecular pharmacology, 1995, Volume: 48, Issue:4

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Analgesics; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Kinetics; Molecular Sequence Data; Mycophenolic Acid; Naltrexone; Narcotic Antagonists; Neuroblastoma; Neurons; Receptors, Opioid, mu; Tritium; Tumor Cells, Cultured

1995
A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding.
    The Journal of biological chemistry, 1993, Nov-05, Volume: 268, Issue:31

    Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Colforsin; Cyclic AMP; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Narcotics; Oligodeoxyribonucleotides; Protein Binding; Receptors, Opioid, delta; Recombinant Proteins; Signal Transduction; Sodium; Structure-Activity Relationship

1993
Modification of G protein-coupled functions by low-pH pretreatment of membranes from NG108-15 cells: increase in opioid agonist efficacy by decreased inactivation of G proteins.
    Molecular pharmacology, 1993, Volume: 44, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Animals; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Rats; Receptors, Opioid; Sodium; Tritium; Tumor Cells, Cultured

1993
mu and delta opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells.
    Neuron, 1993, Volume: 10, Issue:2

    Topics: Affinity Labels; Azides; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Immunosorbent Techniques; Neuroblastoma; Pertussis Toxin; Photochemistry; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured; Virulence Factors, Bordetella

1993
Protein kinase C inhibitor potentiates the agonist-induced GTPase activity in COS cell membranes expressing delta-opioid receptor.
    Brain research. Molecular brain research, 1995, Volume: 33, Issue:2

    Topics: Analgesics; Animals; Cell Line; Cell Membrane; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Leucine; Enzyme Inhibitors; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kidney; Kinetics; Naphthalenes; Protein Kinase C; Receptors, Opioid, delta; Recombinant Proteins; Transfection

1995
Functional role of amino-terminal serine16 and serine27 of G alphaZ in receptor and effector coupling.
    Journal of neurochemistry, 1997, Volume: 68, Issue:6

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Amino Acid Sequence; Analgesics; Cells, Cultured; Cyclic AMP; Dopamine Agonists; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Infant; Kidney; Molecular Sequence Data; Mutagenesis; Pertussis Toxin; Phosphorylation; Quinpirole; Receptors, Opioid, delta; Serine; Signal Transduction; Virulence Factors, Bordetella

1997
Influence of continuous levels of fentanyl in rats on the mu-opioid receptor in the central nervous system.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:1

    Topics: Adenylyl Cyclases; Analgesics; Analgesics, Opioid; Animals; Brain Chemistry; Central Nervous System; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; Guanosine Triphosphate; Male; Membranes; Rats; Rats, Wistar; Receptors, Opioid, mu; Spinal Cord

1997
Nociceptin (orphanin FQ): high-affinity and high-capacity binding site coupled to low-potency stimulation of guanylyl-5'-O-(gamma-thio)-triphosphate binding in rat brain membranes.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2

    Topics: Analgesics, Opioid; Animals; Brain Chemistry; Buffers; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Male; Membranes; Nociceptin; Nociceptin Receptor; Opioid Peptides; Protein Binding; Rats; Rats, Wistar; Receptors, Opioid; Spinal Cord

1998
Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.
    The Biochemical journal, 1999, Aug-15, Volume: 342 ( Pt 1)

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Animals; Azides; Cell Membrane; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoelectric Point; Neuroblastoma; Neurons; Oligodeoxyribonucleotides, Antisense; Oligopeptides; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Tumor Cells, Cultured; Virulence Factors, Bordetella

1999