enkephalin, leucine has been researched along with guanosine triphosphate in 59 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 42 (71.19) | 18.7374 |
1990's | 17 (28.81) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Blume, AJ; Boone, G; Lichtshtein, D | 2 |
Kuhar, MJ; Young, WS | 1 |
Childers, SR; Nijssen, PC; Sexton, T | 1 |
Carter, BD; Medzihradsky, F | 1 |
Olianas, MC; Onali, P | 1 |
Kim, DC; Krumins, SA; Larson, AA | 1 |
Kuhar, MJ; Wamsley, JK; Zarbin, MA | 1 |
Illes, P; Regenold, JT | 1 |
Costa, M; North, RA; Schimerlik, M; Tatsumi, H | 1 |
Krekhnov, BV; Kurochkin, IN; Skliankina, OA; Varfolomeev, SD; Varfolomeeva, AD; Zaĭtsev, SV | 1 |
Costa, T; Herz, A; Ott, S | 1 |
Costa, T; Ott, S | 1 |
Clark, MJ; Medzihradsky, F; Nordby, GL | 1 |
Bidlack, JM; Selley, DE | 1 |
Bowen, WD; Herkenham, M; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB | 1 |
Kamikubo, K; Miura, K; Murase, H; Niwa, M; Nozaki, M; Tsurumi, K | 1 |
Keldysh, PL; Kurochkin, IN; Skliankina, OA; Varfolomeev, SD; Zaĭtsev, SV | 1 |
Barnard, EA; Demoliou-Mason, CD; Wong, YH | 1 |
Duman, RS; Nestler, EJ; Tallman, JF | 1 |
Frances, B; Meunier, JC; Moisand, C | 1 |
Bidlack, JM; Selley, DE; Tyler, CB | 1 |
Brown, SR; Cox, BM; Werling, LL; Zarr, GD | 1 |
Hirobe, M; Konno, F; Sato, Y; Takayanagi, I; Togashi, K | 1 |
Grandt, R; Greiner, C; Jakobs, KH; Zubin, P | 1 |
Costa, T; Herz, A; Vachon, L | 1 |
Coscia, CJ; Moudy, AM; Oetting, GM; Spain, JW; Szücs, M | 1 |
Chung, CT; Hoffman, PL; Tabakoff, B | 1 |
Barg, J; Levy, R; Simantov, R | 1 |
Mizuno, S; Mori, A; Ogawa, N | 1 |
Bennett, DB; Coscia, CJ; Spain, JW | 1 |
Ganten, D; Lang, RE; McDonald, WJ; Notter, M | 1 |
Klee, WA; Koski, G | 1 |
Coy, DH; Kastin, AJ; Luciano, MG; Zadina, JE | 1 |
Franklin, PH; Hoss, W | 1 |
Makman, MH; Walczak, S; Zukin, RS | 1 |
Gintzler, AR; Zukin, RS | 1 |
Herkenham, MA; Kent, JL; Pert, A; Pert, CB; Taylor, DP | 1 |
Chang, KJ; Cuatrecasas, P; Hazum, E | 1 |
Hamprecht, B; Propst, F | 1 |
Chang, JK; Chang, KJ; Cuatrecasas, P; Hazum, E; Lillian, A | 1 |
Chang, KJ; Cuatrecasas, P; Hazum, E; Killian, A | 1 |
Bowen, WD; Gentleman, S; Herkenham, M; Pert, CB | 1 |
Cooper, DM; Gill, DL; Londos, C; Rodbell, M | 1 |
Koehler, JE; Law, PY; Loh, HH | 1 |
Fitz-Syage, ML; Gardner, EL; Gintzler, AR; Sugarman, JR; Zukin, RS; Zukin, SR | 1 |
Costa, T; Krumins, SA; Munson, PJ; Rodbard, D; Shimohigashi, Y | 1 |
Costa, T; Krumins, S; Rodbard, D; Shimohigashi, Y | 1 |
Cermak, D; Dawson, G; Ellory, JC; McLawhon, RW | 1 |
Koehler, JE; Law, PY; Loh, HH; Wu, J | 1 |
Medzihradsky, F; Yabaluri, N | 1 |
Bell, GI; Kong, H; Moe, ST; Portoghese, PS; Raynor, K; Reisine, T; Yasuda, K | 1 |
Breivogel, CS; Childers, SR; Selley, DE | 1 |
Laugwitz, KL; Offermanns, S; Schultz, G; Spicher, K | 1 |
Fukushima, N; Hayashi, C; Katayama, T; Misu, Y; Ueda, H | 1 |
Ho, MK; Wong, YH | 1 |
Albrecht, E; Baeger, I; Berger, H; Fechner, K; Heinrich, N; Lorenz, D; Samovilova, N | 1 |
Albrecht, E; Baeger, I; Berger, H; Oswald, S; Samovilova, NN | 1 |
Allouche, S; Hasbi, A; Homburger, V; Jauzac, P; Polastron, J | 1 |
59 other study(ies) available for enkephalin, leucine and guanosine triphosphate
Article | Year |
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Regulation of the neuroblastoma x glioma hybrid opiate receptors by Na+ and guanine nucleotides.
Topics: Animals; Binding, Competitive; Cell Line; Enkephalins; Glioma; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Neuroblastoma; Receptors, Opioid; Sodium | 1979 |
A new method for receptor autoradiography: [3H]opioid receptors in rat brain.
Topics: Animals; Autoradiography; Brain; Corpus Striatum; Dihydromorphine; Diprenorphine; Enkephalins; Frontal Lobe; Guanosine Triphosphate; Histological Techniques; Male; Rats; Receptors, Opioid; Sodium; Tritium | 1979 |
Coupling of opiate receptors to adenylate cyclase: requirement for Na+ and GTP.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cations, Divalent; Cations, Monovalent; Cell Line; Enkephalins; Guanosine Triphosphate; Membranes; Mice; Neurons; Prostaglandins E; Receptors, Opioid; Sodium | 1979 |
Opioid-inhibited adenylyl cyclase in rat brain membranes: lack of correlation with high-affinity opioid receptor binding sites.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Cell Membrane; Colforsin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Male; Naloxone; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium; Sodium Chloride; Sodium Fluoride | 1992 |
Opioid signal transduction in intact and fragmented SH-SY5Y neural cells.
Topics: Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine Triphosphate; Humans; Intracellular Membranes; Ligands; Nervous System Neoplasms; Signal Transduction; Tumor Cells, Cultured | 1992 |
Naturally occurring opioid receptor agonists stimulate adenylate cyclase activity in rat olfactory bulb.
Topics: Adenylyl Cyclases; Alkaloids; Animals; beta-Endorphin; Calcium; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enzyme Activation; Guanosine Triphosphate; Intracellular Fluid; Kinetics; Male; Naloxone; Olfactory Bulb; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Opioid; Staurosporine; Stimulation, Chemical | 1991 |
Substance P modulation of [3H]DAGO binding in the brain of Swiss-Webster and CXBK (mu opioid receptor deficient) mice.
Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Mice; Mice, Mutant Strains; Receptors, Opioid; Receptors, Opioid, mu; Substance P | 1990 |
Anterograde transport of opioid receptors in rat vagus nerves and dorsal roots of spinal nerves: pharmacology and sensitivity to sodium and guanine nucleotides.
Topics: Animals; Axonal Transport; Colchicine; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guanosine Triphosphate; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride; Spinal Nerve Roots; Vagus Nerve | 1990 |
Interaction between neuropeptide Y and noradrenaline on central catecholamine neurons.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Locus Coeruleus; Neuropeptide Y; Norepinephrine; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, mu; Thionucleotides; Yohimbine | 1990 |
Potassium conductance increased by noradrenaline, opioids, somatostatin, and G-proteins: whole-cell recording from guinea pig submucous neurons.
Topics: Adrenergic alpha-Agonists; Animals; Dialysis; Electric Conductivity; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Narcotics; Neurons; Norepinephrine; Pertussis Toxin; Potassium; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, delta; Somatostatin; Submucous Plexus; Thionucleotides; Time Factors; Virulence Factors, Bordetella | 1990 |
[Kinetic characteristics of the effect of GTP on properties of opioid receptors].
Topics: Adenine Nucleotides; Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Kinetics; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1990 |
Opioid receptors of neuroblastoma cells are in two domains of the plasma membrane that differ in content of G proteins.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Fractionation; Cell Membrane; Centrifugation; Diprenorphine; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Neuroblastoma; Pertussis Toxin; Receptors, Opioid; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Enzymatic degradation of GTP and its "stable" analogues produce apparent isomerization of opioid receptors.
Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Thionucleotides | 1989 |
Relationship between opioid-receptor occupancy and stimulation of low-Km GTPase in brain membranes.
Topics: Animals; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP Phosphohydrolases; Guanosine Triphosphate; Magnesium; Membranes; Naltrexone; Oligopeptides; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium | 1989 |
Guanine nucleotide regulation of [125I]beta-endorphin binding to NG108-15 and SK-N-SH cell membranes: specific cation requirements.
Topics: beta-Endorphin; Cations; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Glioma; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Hybrid Cells; Neuroblastoma; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride; Tumor Cells, Cultured | 1989 |
A quantitative study of [3H]D-Ala2-D-Leu5-enkephalin binding to rat brain membranes. Evidence that oxymorphone is a noncompetitive inhibitor of the lower affinity delta-binding site.
Topics: Animals; Autoradiography; Brain; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Hydromorphone; Male; Manganese; Manganese Compounds; Mathematics; Membranes; Oligopeptides; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride | 1985 |
Adrenal medullary opioid receptors are linked to GTP-binding proteins, pertussis toxin substrates.
Topics: Adenylate Cyclase Toxin; Adrenal Medulla; Animals; Cattle; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Pertussis Toxin; Receptors, Opioid; Virulence Factors, Bordetella | 1986 |
[A kinetic model of the interaction of stable GTP analogs with a system of opioid receptors].
Topics: Animals; Binding, Competitive; Brain; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Ligands; Male; Models, Biological; Morphine; Naloxone; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid | 1988 |
ADP-ribosylation with pertussis toxin modulates the GTP-sensitive opioid ligand binding in digitonin-soluble extracts of rat brain membranes.
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cell Membrane; Digitonin; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Receptors, Opioid; Sodium; Solubility; Virulence Factors, Bordetella | 1988 |
Acute and chronic opiate-regulation of adenylate cyclase in brain: specific effects in locus coeruleus.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Locus Coeruleus; Male; Morphine; Narcotics; Neurons; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Time Factors; Virulence Factors, Bordetella | 1988 |
Na+ ions and Gpp(NH)p selectively inhibit agonist interactions at mu- and kappa-opioid receptor sites in rabbit and guinea-pig cerebellum membranes.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzomorphans; Binding, Competitive; Cerebellum; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium | 1985 |
Guanine nucleotide regulation of [125I]beta-endorphin binding to rat brain membranes: monovalent cation requirement.
Topics: Animals; beta-Endorphin; Brain; Cations, Monovalent; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Lithium; Male; Phenazocine; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride | 1988 |
Opioid binding to rat and guinea-pig neural membranes in the presence of physiological cations at 37 degrees C.
Topics: Animals; Brain; Cations; Cyclazocine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Male; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Temperature; Tritium | 1985 |
Interactions of codeine-7,8-oxide (codeine-epoxide), as a new metabolite of codeine, with multiple opiate receptors.
Topics: Animals; Brain; Cell Membrane; Codeine; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guanosine Triphosphate; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride | 1985 |
Bradykinin stimulates GTP hydrolysis in NG108-15 membranes by a high-affinity, pertussis toxin-insensitive GTPase.
Topics: Bradykinin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Hybrid Cells; Hydrolysis; Membranes; Neuroblastoma; Pertussis Toxin; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Virulence Factors, Bordetella | 1986 |
Differential sensitivity of basal and opioid-stimulated low Km GTPase to guanine nucleotide analogs.
Topics: Animals; Cell Line; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; GTP Phosphohydrolases; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Phosphoric Monoester Hydrolases; Structure-Activity Relationship; Thionucleotides | 1986 |
Guanine nucleotide and cation regulation of mu, delta, and kappa opioid receptor binding: evidence for differential postnatal development in rat brain.
Topics: Animals; Brain; Cations; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Manganese; Manganese Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Chloride | 1987 |
Effects of ethanol, temperature, and endogenous regulatory factors on the characteristics of striatal opiate receptors.
Topics: Animals; Corpus Striatum; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethanol; Guanosine Triphosphate; Male; Mice; Mice, Inbred C57BL; Receptors, Opioid; Sodium; Temperature | 1984 |
Up-regulation of opiate receptors by opiate antagonists in neuroblastoma-glioma cell culture: the possibility of interaction with guanosine triphosphate-binding proteins.
Topics: Animals; Cells, Cultured; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glioma; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Naloxone; Neuroblastoma; Rats; Receptors, Opioid; Receptors, Opioid, delta | 1984 |
Interaction of enkephalin with opioid receptors of brain membranes: regulation by essential transition metals, guanine nucleotides and temperature.
Topics: Animals; Copper; Enkephalins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium; Temperature; Zinc | 1984 |
Gpp(NH)p promotes the formation of a low affinity state for the delta opioid agonist-receptor complex.
Topics: Animals; Cattle; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; In Vitro Techniques; Kinetics; Receptors, Opioid; Receptors, Opioid, delta; Synaptic Membranes | 1984 |
Influence of intracerebroventricular (ICV) GTP-electrolyte infusion on ICV (D-ALA2, D-LEU5) enkephalin (DADL)-induced cardiovascular effects in rats.
Topics: Animals; Blood Pressure; Chlorides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Heart Rate; Injections, Intraventricular; Male; Manganese; Manganese Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride | 1984 |
Opiates inhibit adenylate cyclase by stimulating GTP hydrolysis.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cell Membrane; Enkephalin, Leucine-2-Alanine; Enkephalins; GTP Phosphohydrolases; Guanosine Triphosphate; Phosphoric Monoester Hydrolases; Rats; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship | 1981 |
Mu and delta opiate receptors in rat brain are affected by GTP but not by MIF-1.
Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanosine Triphosphate; Male; MSH Release-Inhibiting Hormone; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium; Temperature | 1981 |
Opiates stimulate low Km GTPase in brain.
Topics: Adenylyl Cyclase Inhibitors; Animals; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; GTP Phosphohydrolases; Guanosine Triphosphate; Male; Naloxone; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
GTP modulation of opiate receptors in regions of rat brain and possible mechanism of GTP action.
Topics: Amygdala; Animals; Brain; Corpus Striatum; Enkephalins; Frontal Lobe; Guanosine Triphosphate; Hippocampus; Male; Naloxone; Rats; Receptors, Opioid | 1980 |
Guanyl nucleotide interactions with opiate receptors in guinea pig brain and ileum.
Topics: Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Ileum; Kinetics; Male; Morphine Derivatives; Organ Specificity; Receptors, Opioid | 1980 |
Biochemical and autoradiographic evidence for type 1 and type 2 opiate receptors.
Topics: Animals; Autoradiography; Brain; Enkephalins; Guanosine Triphosphate; Ligands; Naloxone; Rats; Receptors, Opioid | 1980 |
Possible role of distinct morphine and enkephalin receptors in mediating actins of benzomorphan drugs (putative kappa and sigma agonists).
Topics: Animals; Benzomorphans; Brain; Cyclazocine; Diprenorphine; Endorphins; Enkephalins; Ethylketocyclazocine; Guanosine Triphosphate; Morphinans; Morphine; Naloxone; Neuroblastoma; Rats; Receptors, Opioid; Sodium; Synaptic Membranes | 1980 |
Opioids, noradrenaline and GTP analogs inhibit cholera toxin activated adenylate cyclase in neuroblastoma x glioma hybrid cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Clone Cells; Diphosphonates; Endorphins; Enkephalin, Methionine; Enkephalins; Glioma; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Mice; Morphine; Neuroblastoma; Norepinephrine; Rats | 1981 |
Morphiceptin (NH4-tyr-pro-phe-pro-COHN2): a potent and specific agonist for morphine (mu) receptors.
Topics: Animals; Binding, Competitive; Caseins; Dihydromorphine; Endorphins; Enkephalins; Guanosine Triphosphate; Guinea Pigs; Ileum; Male; Mice; Naloxone; Rats; Receptors, Opioid; Sodium; Vas Deferens | 1981 |
Interactions of ligands with morphine and enkephalin receptors are differentially affected by guanine nucleotide.
Topics: Animals; Brain; Cells, Cultured; Diprenorphine; Endorphins; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Magnesium; Naloxone; Neoplasms, Experimental; Neuroblastoma; Rats; Receptors, Opioid; Sodium | 1981 |
Interconverting mu and delta forms of the opiate receptor in rat striatal patches.
Topics: Adenylyl Cyclases; Animals; Cations, Divalent; Corpus Striatum; Dithiothreitol; Enkephalins; Guanosine Triphosphate; Male; Membrane Fluidity; Morphine; Rats; Receptors, Opioid; Temperature | 1981 |
Opiate receptor-mediated inhibition of adenylate cyclase in rat striatal plasma membranes.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Guanosine Triphosphate; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Comparison of opiate inhibition of adenylate cyclase activity in neuroblastoma N18tG2 and neuroblastoma x glioma NG108-15 hybrid cell lines.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cyclic AMP; Enkephalins; Glioma; Guanosine Triphosphate; Hybrid Cells; Kinetics; Mice; Narcotics; Neoplasms, Experimental; Neuroblastoma; Rats; Receptors, Opioid | 1982 |
Naltrexone-induced opiate receptor supersensitivity.
Topics: Animals; Brain; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Female; Guanosine Triphosphate; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Differential effects of GTP and cations on binding of labeled dimeric and monomeric enkephalins to neuroblastoma-glioma cell delta opiate receptors.
Topics: Animals; Binding, Competitive; Cell Line; Enkephalins; Glioma; Guanosine Triphosphate; Hybrid Cells; Kinetics; Macromolecular Substances; Manganese; Mice; Neuroblastoma; Rats; Receptors, Opioid; Receptors, Opioid, delta; Sodium | 1982 |
Dimeric pentapeptide and tetrapeptide enkephalins: new tools for the study of delta opioid receptors.
Topics: Animals; Cyclic AMP; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, delta | 1983 |
Glycosylation-dependent regulation of opiate (enkephalin) receptors in neurotumor cells.
Topics: Animals; Carbohydrate Metabolism; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Mice; Neoplasms, Nerve Tissue; Rats; Receptors, Opioid; Tunicamycin | 1983 |
Demonstration and characterization of opiate inhibition of the striatal adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Animals; Chlorides; Corpus Striatum; Endorphins; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Manganese; Manganese Compounds; Naloxone; Rats; Sodium Chloride; Sodium Fluoride; Stereoisomerism | 1981 |
Reversible modulation of opioid receptor binding in intact neural cells by endogenous guanosine triphosphate.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Analgesics; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Kinetics; Molecular Sequence Data; Mycophenolic Acid; Naltrexone; Narcotic Antagonists; Neuroblastoma; Neurons; Receptors, Opioid, mu; Tritium; Tumor Cells, Cultured | 1995 |
A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding.
Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Colforsin; Cyclic AMP; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Narcotics; Oligodeoxyribonucleotides; Protein Binding; Receptors, Opioid, delta; Recombinant Proteins; Signal Transduction; Sodium; Structure-Activity Relationship | 1993 |
Modification of G protein-coupled functions by low-pH pretreatment of membranes from NG108-15 cells: increase in opioid agonist efficacy by decreased inactivation of G proteins.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Animals; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Rats; Receptors, Opioid; Sodium; Tritium; Tumor Cells, Cultured | 1993 |
mu and delta opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells.
Topics: Affinity Labels; Azides; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Immunosorbent Techniques; Neuroblastoma; Pertussis Toxin; Photochemistry; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Protein kinase C inhibitor potentiates the agonist-induced GTPase activity in COS cell membranes expressing delta-opioid receptor.
Topics: Analgesics; Animals; Cell Line; Cell Membrane; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Leucine; Enzyme Inhibitors; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kidney; Kinetics; Naphthalenes; Protein Kinase C; Receptors, Opioid, delta; Recombinant Proteins; Transfection | 1995 |
Functional role of amino-terminal serine16 and serine27 of G alphaZ in receptor and effector coupling.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Amino Acid Sequence; Analgesics; Cells, Cultured; Cyclic AMP; Dopamine Agonists; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Infant; Kidney; Molecular Sequence Data; Mutagenesis; Pertussis Toxin; Phosphorylation; Quinpirole; Receptors, Opioid, delta; Serine; Signal Transduction; Virulence Factors, Bordetella | 1997 |
Influence of continuous levels of fentanyl in rats on the mu-opioid receptor in the central nervous system.
Topics: Adenylyl Cyclases; Analgesics; Analgesics, Opioid; Animals; Brain Chemistry; Central Nervous System; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; Guanosine Triphosphate; Male; Membranes; Rats; Rats, Wistar; Receptors, Opioid, mu; Spinal Cord | 1997 |
Nociceptin (orphanin FQ): high-affinity and high-capacity binding site coupled to low-potency stimulation of guanylyl-5'-O-(gamma-thio)-triphosphate binding in rat brain membranes.
Topics: Analgesics, Opioid; Animals; Brain Chemistry; Buffers; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Male; Membranes; Nociceptin; Nociceptin Receptor; Opioid Peptides; Protein Binding; Rats; Rats, Wistar; Receptors, Opioid; Spinal Cord | 1998 |
Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Animals; Azides; Cell Membrane; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoelectric Point; Neuroblastoma; Neurons; Oligodeoxyribonucleotides, Antisense; Oligopeptides; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1999 |