enkephalin, leucine has been researched along with enkephalinamide-met, ala(2)- in 129 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 110 (85.27) | 18.7374 |
| 1990's | 17 (13.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (1.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| del Río, J; Garzón, J; Moratalla, R | 1 |
| Bennett, DJ; Cripps, MM | 1 |
| deCosta, B; Jiang, Q; Porreca, F; Rice, KC | 1 |
| Frank, C; Proietti, ML; Sagratella, S; Scotti De Carolis, A; Trampus, M | 2 |
| Kameyama, T; Katoh, A; Nabeshima, T | 1 |
| Hill, JM; Kaufman, MP | 1 |
| Laurent, S; Marsh, JD; Smith, TW | 1 |
| Finesso, M; Gorio, A; Prosdocimi, M | 1 |
| Cador, M; Kelley, AE; Le Moal, M; Stinus, L | 1 |
| Burks, TF; Gehrig, CA; Hruby, VJ; Lemcke, PK; Shook, JE | 1 |
| Cadet, P; Scharrer, B; Stefano, GB | 1 |
| Heyman, JS; Jiang, Q; Mosberg, HI; Porreca, F; Rothman, RB | 1 |
| Blancquaert, JP; Lefebvre, RA; Willems, JL | 1 |
| Frey, EA; Jacobson, AE; Rice, KC; Tocque, B | 1 |
| Childers, SR | 1 |
| Rand, MJ; Wong-Dusting, H | 1 |
| Henke, PG; Ray, A; Sullivan, RM | 1 |
| Aliab'eva, TN; Balashov, AM; Bumialis, VV; Panchenko, LF; Petrichenko, OB | 1 |
| Magee, AI; Milligan, G; Mullaney, I; Unson, CG | 1 |
| Deguchi, T; Yokoyama, E | 1 |
| Mergenhagen, S; Pert, CB; Ruff, MR; Wahl, SM | 1 |
| Kalivas, PW; Miller, JS; Taylor, S | 1 |
| Assanah, P; Ford, R; Harper, J; Jackson, DM; Leung, MK; Stefano, GB; Tetrault, L; Torres, JC | 1 |
| Akita, K; Hatanaka, H; Maruyama, M; Sugino, H | 1 |
| Bueno, L; Fargeas, MJ; Primi, MP | 1 |
| Cunningham, FJ; Stansfield, SC | 1 |
| Benyhe, S; Borsodi, A; Simon, J; Szücs, M; Wollemann, M | 1 |
| Krumins, SA; Rodbard, D | 1 |
| Benyhe, S; Borsodi, A; Di Gléria, K; Kevei, J; Medzihradszky, K; Süli-Vargha, H; Szécsi, J; Szücs, M; Tóth, G | 1 |
| Rand, MJ; Wong-Dusting, HK | 1 |
| Haddad, GG; Schaeffer, JI | 1 |
| Portoghese, PS; Takemori, AE | 1 |
| Laubie, M; Schmitt, H | 1 |
| Coscia, CJ; Devane, WA; Howlett, AC; Spain, JW | 1 |
| Greenspan, DL; Musacchio, JM | 1 |
| Kotlińska, J; Langwiński, R | 1 |
| Duffy, P; Kalivas, PW; Latimer, LG | 1 |
| Madamba, SG; Moore, SD; Siggins, GR; Zieglgänsberger, W | 1 |
| Arita, JA; Kimura, K | 1 |
| Del Rio, J; Fernandez-Tome, MP; Gonzalez, Y | 1 |
| Hanley, DF; Kirsch, JR; Traystman, RJ; Wilson, DA | 1 |
| Schwartz, JP | 1 |
| Hartvig, P; Långström, B; Lärkfors, L; Lundberg, PO; Lundqvist, H; Muhr, C; Någren, K; Terenius, L | 1 |
| Frank, GB; Sudha, TS | 1 |
| Haddad, GG; Jeng, HJ; Lai, TL | 1 |
| Abhold, R; Kalivas, PW | 1 |
| Kashi, SD; Lee, VH | 2 |
| Bentley, AM; Wallis, M | 1 |
| Chan, YS; Cheung, YM; Hwang, JC; Poon, PW; Wong, CL; Wong, TM | 1 |
| Bueno, L; Fargeas, MJ; Fioramonti, J; Hondé, C; Primi, MP | 1 |
| Agmo, A; de Avila, N | 1 |
| Saunders, WS; Thornhill, JA | 1 |
| Asdourian, D; Geula, C | 1 |
| Matsui, H; Yamamoto, C | 1 |
| Bardon, T; Pairet, M; Ruckebusch, Y | 1 |
| Chin, CA; Djamgoz, MB; Lam, DM; Stell, WK | 1 |
| Groves, PM; Ling, N; Nakamura, S; Tepper, JM; Young, SJ | 1 |
| Hoffer, BJ; Olson, L; Palmer, MR; Seiger, A | 1 |
| Franklin, PH; Hoss, W | 1 |
| Sun, FY; Yu, GH; Zhang, AZ; Zhang, LM | 1 |
| Dick, E; Miller, RF | 1 |
| Forchetti, CM; Marco, EJ; Meek, JL | 1 |
| Gintzler, AR; Zukin, RS | 1 |
| Huidobro, F; Huidobro-Toro, JP | 1 |
| Huidobro-Toro, JP; Way, EL | 1 |
| Byrne, WL; Codd, EE | 1 |
| Audigier, Y; Cros, J; Gairin, JE; Haran, R; Mazarguil, H | 1 |
| Coscia, CJ; Laskowski, MB; Roth, BL | 1 |
| Adler, MW; Cowan, A; Tortella, FC | 1 |
| Blume, AJ; Fantozzi, R; Mullikin-Kilpatrick, D | 1 |
| Appel, NM; Van Loon, GR | 1 |
| Scharrer, B; Stefano, GB | 1 |
| Pasternak, GW; Wolozin, BL | 1 |
| Cowan, A; Tortella, FC | 1 |
| Bernardini, GL; Clark, WG | 2 |
| Adames, C; Fearon, Z; Guerrero-Muñoz, F; Way, EL | 1 |
| Sapru, HN; Willette, RN | 1 |
| Dornay, M; Simantov, R | 1 |
| Dewey, WL; Fu, TC; Jones, D; Martin, BR; Ohlsson, AE | 1 |
| Grace, M; Kneip, J; Levine, AS; Morley, JE; Murray, SS | 1 |
| Krieger, AJ; Sapru, HN; Willette, RN | 1 |
| Chesselet, MF; Glowinski, J; Lubetzki, C | 1 |
| Catapane, EJ; Kream, RM; Stefano, GB | 1 |
| Baram, D; Levy, R; Simantov, R | 1 |
| Rothman, R; Westfall, TC | 1 |
| Kameyama, T; Ukai, M | 1 |
| Brown, DR; Miller, RJ | 1 |
| Connor, JD; Drust, EG | 1 |
| Charnay, Y; Dray, F; Dubois, PM; Leger, L | 1 |
| Hsiao, S; Inouye, K; Itoh, S; Katsuura, G | 1 |
| Chaillet, P; Costentin, J; Lecomte, JM; Marçais, H; Natan, LB; Uchida, G | 1 |
| de Groat, WC; Hisamitsu, T | 1 |
| Balderrama, N; Maldonado, H; Miralto, A; Núñez, J | 1 |
| Moreton, JE; Tortella, FC | 1 |
| Allerton, HW; Isom, GE; Zobrist, RH | 1 |
| Bellet, M; Elghozi, JL; Meyer, P | 1 |
| del Río, J; Garzón, J; Rubio, J | 1 |
| Brady, LS; Holtzman, SG | 2 |
| Bloom, FE; Iversen, SD; Joyce, EM; Koob, GF; Strecker, R | 1 |
| Algeri, S; Altstein, M; de Simone, GM; Guardabasso, V | 1 |
| Macdonald, RL; Werz, MA | 1 |
| Jones, CA; Marchbanks, RM | 1 |
| LePiane, FG; Phillips, AG | 1 |
| Barbeau, A; Izumi, K; Munekata, E; Nakanishi, T; Wong, P; Yamamoto, H; Yoshida, M | 1 |
| Flack, HG; Huston, JP; Welzl, H | 1 |
| Huston, JP; Oitzl, MS; Ornstein, K; Sprick, U | 1 |
| Chéramy, A; Chesselet, MF; Glowinski, J; Reisine, TD | 1 |
| Barbeau, A; Izumi, K; Munekata, E; Nakanishi, T; Yamamoto, H | 1 |
| Burks, TF; Galligan, JJ; Miller, MS | 1 |
| Khan, MF | 1 |
| De Sarro, GB; Marmo, E; Naccari, F; Nisticõ, G; Rotiroti, D | 1 |
| Coy, DH; Dunlap, WP; Harston, CT; Spirtes, MA | 1 |
| Shahabi, NA; Sharp, BM | 1 |
| Hinson, JP; Kapas, S; Purbrick, A | 1 |
| Everitt, BJ; Phillips, GD; Robbins, TW | 1 |
| Capron, A; Duvaux-Miret, O; Leung, MK; Stefano, GB | 1 |
| Amoroso, D; Catozzi, L; Ceppi, E; Groppetti, A; Guglielmetti, F; Palazzi, E | 1 |
| Bhatia, SC; Kumar, VM; Manchanda, SK; Nayar, U; Poddar, A; Saha, S | 1 |
| Casares, F; Liu, U; Stefano, GB | 1 |
| Bhatia, SC; Manchanda, SK; Nayar, U; Saha, SN | 1 |
| Chakrabarti, S; Law, PY; Loh, HH | 1 |
| Hebb, AL; Maddeaux, C; Marsh, NJ; Mendella, PD; Zacharko, RM | 1 |
| Fukunaga, Y; Inoue, N; Kishioka, S; Miyamoto, M; Yamamoto, H | 1 |
| Karatayev, O; Leibowitz, SF; Liang, S; Morganstern, I; Ye, Z | 1 |
| Barson, JR; Chen, A; Chen, YW; Hoebel, BG; Leibowitz, SF | 1 |
2 review(s) available for enkephalin, leucine and enkephalinamide-met, ala(2)-
| Article | Year |
|---|---|
[Enkephalinergic regulation of cardiovascular centers].
Topics: Animals; Blood Pressure; Brain Mapping; Cardiovascular Physiological Phenomena; Cats; Dextromoramide; Dogs; Enkephalin, Methionine; Enkephalins; Heart Rate; Medulla Oblongata; Naloxone; Naltrexone; Nervous System Physiological Phenomena; Pressoreceptors; Rats; Receptors, Opioid; Reflex; Reticular Formation; Sympathetic Nervous System; Vagus Nerve; Vasomotor System | 1985 |
[The co-localization of monoamines and enkephalins in the central nervous system].
Topics: 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Amines; Animals; Brain; Catecholamines; Cats; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Histocytochemistry; Hydroxydopamines; Hypothalamus; Immunologic Techniques; Locus Coeruleus; Neurons; Norepinephrine; Oxidopamine; Protein Precursors; Raphe Nuclei; Rats; Serotonin; Tissue Distribution | 1984 |
127 other study(ies) available for enkephalin, leucine and enkephalinamide-met, ala(2)-
| Article | Year |
|---|---|
[Monoaminergic modulation of the analgesia induced in rats by (D-Ala2)-met-enkephalinamide (DADA)].
Topics: Analgesics; Animals; Biogenic Amines; Drug Interactions; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Monoamine Oxidase Inhibitors; Morphine; Rats | 1979 |
Proenkephalin A derivatives in lacrimal gland: occurrence and regulation of lacrimal function.
Topics: Adenylyl Cyclases; Animals; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Lacrimal Apparatus; Male; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1992 |
Effects of oxymorphindole on morphine induced-antinociception in mice and rats.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Mice; Morphine; Morpholines; Rats; Receptors, Opioid; Receptors, Opioid, delta | 1990 |
An in vitro study on the hippocampal epileptogenic properties of enkephalins and enkephalinase inhibitors in rats.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Epilepsy; Hippocampus; In Vitro Techniques; Male; Morphine; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Interaction between enkephalinergic and dopaminergic systems in stressful situations.
Topics: Animals; Apomorphine; Conditioning, Operant; Corpus Striatum; Dopamine; Enkephalin, Methionine; Enkephalins; Hydroxydopamines; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurons; Oxidopamine; Pimozide; Receptors, Dopamine; Stress, Psychological | 1991 |
An in vitro study on the hippocampal electrophysiological properties of enkephalinase inhibitors in rats.
Topics: Animals; Dipeptides; Electric Stimulation; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Neprilysin; Perfusion; Rats; Rats, Inbred Strains; Thiorphan | 1991 |
Attenuation of reflex pressor and ventilatory responses to static muscular contraction by intrathecal opioids.
Topics: Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Heart Rate; Injections, Spinal; Muscle Contraction; Respiration; Sciatic Nerve | 1990 |
Enkephalins increase cyclic adenosine monophosphate content, calcium uptake, and contractile state in cultured chick embryo heart cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Chick Embryo; Cyclic AMP; Enkephalin, Methionine; Enkephalins; GTP-Binding Proteins; Heart; Myocardial Contraction; Myocardium; Naloxone | 1986 |
Enkephalin modulation of neural transmission in the cat stellate ganglion: pharmacological actions of exogenous opiates.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Cats; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Ganglia, Sympathetic; Heart Rate; Histamine; Male; Morphine; Synaptic Transmission | 1986 |
Neurotensin, substance P, neurokinin-alpha, and enkephalin: injection into ventral tegmental area in the rat produces differential effects on operant responding.
Topics: Animals; Conditioning, Operant; Dextroamphetamine; Enkephalin, Methionine; Enkephalins; Injections; Male; Neurokinin A; Neurotensin; Rats; Rats, Inbred Strains; Reinforcement Schedule; Substance P; Tegmentum Mesencephali | 1989 |
Antidiarrheal properties of supraspinal mu and delta and peripheral mu, delta and kappa opioid receptors: inhibition of diarrhea without constipation.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antidiarrheals; Constipation; Dose-Response Relationship, Drug; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Gastrointestinal Motility; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1989 |
Stimulatory effects of opioid neuropeptides on locomotory activity and conformational changes in invertebrate and human immunocytes: evidence for a subtype of delta receptor.
Topics: Animals; Bivalvia; Cell Movement; Enkephalin, Methionine; Enkephalins; Humans; In Vitro Techniques; Insecta; Lymphocytes; Receptors, Opioid; Receptors, Opioid, delta; Species Specificity; Structure-Activity Relationship | 1989 |
Modulation of mu-mediated antinociception by delta agonists: characterization with antagonists.
Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1989 |
Antiaversive properties of opioids in the conditioned taste aversion test in the rat.
Topics: Animals; Avoidance Learning; Conditioning, Classical; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Fentanyl; Male; Methadone; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Taste | 1987 |
The mu-opioid receptor in the 7315c tumor cell.
Topics: Cell Membrane; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Oligopeptides; Receptors, Opioid; Receptors, Opioid, mu; Tumor Cells, Cultured | 1987 |
Opiate-inhibited adenylate cyclase in rat brain membranes depleted of Gs-stimulated adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Brain; Cell Membrane; Cholera Toxin; Colforsin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Male; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Fluoride; Virulence Factors, Bordetella | 1988 |
Effects of the opioid peptides [Met5]enkephalin-Arg6-Phe7 and [Met5]enkephalin-Arg6-Gly7-Leu8 on cholinergic neurotransmission in the rabbit isolated atria.
Topics: Animals; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; Female; Heart; Heart Rate; In Vitro Techniques; Male; Naloxone; Parasympathetic Nervous System; Propranolol; Rabbits; Synaptic Transmission | 1987 |
Opiate mechanisms in the central amygdala and gastric stress pathology in rats.
Topics: Amygdala; Animals; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Male; Microinjections; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 1988 |
[Specific binding of mu- and delta-ligands by opiate receptors in the rat brain in the presence of reaferon].
Topics: Animals; Binding, Competitive; Brain; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; In Vitro Techniques; Interferon alpha-2; Interferon Type I; Interferon-alpha; Ligands; Male; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Recombinant Proteins | 1988 |
Differential regulation of amounts of the guanine-nucleotide-binding proteins Gi and Go in neuroblastoma x glioma hybrid cells in response to dibutyryl cyclic AMP.
Topics: Bucladesine; Cell Differentiation; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Glioma; GTP-Binding Proteins; Hybrid Cells; Neuroblastoma; Time Factors | 1988 |
Monoclonal antibody to enkephalins with binding characteristics similar to opiate receptor.
Topics: alpha-Endorphin; Animals; Antibodies, Monoclonal; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Mice; Morphine; Naloxone; Receptors, Opioid | 1985 |
Opiate receptor-mediated chemotaxis of human monocytes.
Topics: beta-Endorphin; Chemotaxis; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Humans; In Vitro Techniques; Monocytes; Peptide Fragments; Receptors, Opioid | 1985 |
Sensitization to repeated enkephalin administration into the ventral tegmental area of the rat. I. Behavioral characterization.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Administration Schedule; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Male; Microinjections; Motor Activity; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1985 |
A behavioral role for enkephalins in regulating locomotor activity in the insect Leucophaea maderae: evidence for high affinity kappa-like opioid binding sites.
Topics: Animals; Enkephalin, Methionine; Enkephalins; Morphine; Motor Activity; Orthoptera; Receptors, Opioid; Receptors, Opioid, kappa | 1986 |
Binding characteristics of [3H]opioid ligands to active opioid binding sites solubilized from rat brain membranes by glycodeoxycholate and NaCl: the recovery of binding activity by dilution.
Topics: Animals; Brain; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Glycodeoxycholic Acid; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride; Solutions | 1987 |
Central mu, delta- and kappa-opioid influences on intestinal water and electrolyte transport in dogs.
Topics: Animals; Body Water; Cerebral Ventricles; Cholera Toxin; Dogs; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Intestinal Absorption; Potassium; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reference Values; Sodium; Vagotomy | 1988 |
Modulation by endogenous opioid peptides of the secretion of LHRH from cockerel (Gallus domesticus) mediobasal hypothalamic tissue.
Topics: Animals; beta-Endorphin; Chickens; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Male; Naloxone | 1987 |
Separation of kappa-opioid receptor subtype from frog brain.
Topics: Animals; Brain Chemistry; Centrifugation, Density Gradient; Chromatography, Gel; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Rana esculenta; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
Comparative studies of the binding of dimeric and monomeric enkephalins to neuroblastoma-glioma NG108-15 cells.
Topics: Animals; Cell Line; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Glioma; Neuroblastoma; Receptors, Opioid; Tritium | 1985 |
Characterization of rat brain opioid receptors by [Tyr-3,5-3H]1, D-Ala2, Leu5-enkephalin binding.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Methionine; Enkephalins; Kinetics; Rats; Receptors, Opioid; Tritium | 1985 |
Effect of [D-Ala2,Met5]enkephalinamide and [D-Ala2,D-Leu5]enkephalin on cholinergic and noradrenergic neurotransmission in isolated atria.
Topics: Acetylcholine; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Naloxone; Norepinephrine; Rabbits; Rats; Synaptic Transmission; Tetrodotoxin | 1985 |
Regulation of ventilation and oxygen consumption by delta- and mu-opioid receptor agonists.
Topics: Animals; Blood Gas Analysis; Carbon Dioxide; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Hydrogen-Ion Concentration; Naloxone; Oxygen; Oxygen Consumption; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration | 1985 |
Receptors for opioid peptides in the guinea-pig ileum.
Topics: Alkylation; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 1985 |
An assessment of the role of opioid receptors in the response to cannabimimetic drugs.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cannabinoids; Cell Line; Dronabinol; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Morphine; Naltrexone; Neuroblastoma; Neurons; Receptors, Opioid; Receptors, Opioid, delta | 1986 |
The adenylate cyclase rebound response to naloxone in the NG108-15 cells. Effects of etorphine and other opiates.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Glioma; Morphinans; Morphine; Naloxone; Neuroblastoma; Receptors, Opioid | 1986 |
Audiogenic seizures during ethanol withdrawal can be blocked by a delta opioid agonist.
Topics: Acoustic Stimulation; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethanol; Female; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures; Substance Withdrawal Syndrome | 1986 |
Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Male; Motor Activity; Naloxone; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Tegmentum Mesencephali | 1987 |
Enkephalin analogues depress synaptic potentials in rat dentate granule cells recorded intracellularly in vitro.
Topics: Action Potentials; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Hippocampus; In Vitro Techniques; Male; Naloxone; Rats; Rats, Inbred Strains | 1988 |
Enkephalin inhibits dopamine synthesis in vitro in the median eminence portion of rat hypothalamic slices.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Calcium; Dihydroxyphenylalanine; Dopamine; Enkephalin, Methionine; Enkephalins; Female; Haloperidol; Hypothalamus; In Vitro Techniques; Median Eminence; Neurons; Rats; Rats, Inbred Strains | 1988 |
Interaction between opioid agonists or naloxone and 5-HTP on feeding behavior in food-deprived rats.
Topics: 5-Hydroxytryptophan; Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Feeding Behavior; Food Deprivation; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains | 1988 |
Effect of centrally administered encephalinamides on regional cerebral blood flow in the dog.
Topics: Animals; Brain; Cerebrovascular Circulation; Cisterna Magna; Dogs; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Female; Injections; Male; Regional Blood Flow; Tissue Distribution | 1988 |
Chronic exposure to opiate agonists increases proenkephalin biosynthesis in NG108 cells.
Topics: Animals; Cell Line; Colforsin; Enkephalin, Methionine; Enkephalins; Etorphine; Genes; Glioma; Hybrid Cells; Morphinans; Morphine; Naloxone; Neuroblastoma; Protein Precursors; RNA, Messenger; Transcription, Genetic | 1988 |
Kinetics of four 11C-labelled enkephalin peptides in the brain, pituitary and plasma of rhesus monkeys.
Topics: Animals; Biological Transport, Active; Brain; Enkephalin, Methionine; Enkephalins; Kinetics; Macaca mulatta; Pituitary Gland; Tomography, Emission-Computed | 1986 |
Effects of enkephalin, applied intracellularly, on action potentials in vertebrate A and C nerve fibre axons.
Topics: Action Potentials; Animals; Enkephalin, Leucine; Enkephalin, Methionine; Guinea Pigs; In Vitro Techniques; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Rabbits; Rana pipiens; Sciatic Nerve; Vagus Nerve | 1987 |
Effect of endorphins on heart rate and blood pressure in adult dogs.
Topics: Animals; Atropine; Blood Pressure; Consciousness; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Heart; Heart Rate; Naloxone; Naltrexone | 1986 |
Enkephalin release into the ventral tegmental area in response to stress: modulation of mesocorticolimbic dopamine.
Topics: Animals; Dopamine; Electroshock; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Frontal Lobe; Male; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Septal Nuclei; Stress, Physiological; Tegmentum Mesencephali | 1987 |
Enkephalin hydrolysis in homogenates of various absorptive mucosae of the albino rabbit: similarities in rates and involvement of aminopeptidases.
Topics: Aminopeptidases; Animals; Cheek; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Hydrolysis; Ileum; Intestinal Mucosa; Mouth Mucosa; Mucous Membrane; Nasal Mucosa; Peptide Fragments; Rabbits; Rectum; Vagina | 1986 |
Hydrolysis of enkephalins in homogenates of anterior segment tissues of the albino rabbit eye.
Topics: Animals; Anterior Eye Segment; Ciliary Body; Cornea; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Epithelium; Half-Life; Hydrolysis; Rabbits; Tears | 1986 |
Effects of two enkephalin analogues, morphine sulphate, dopamine and naloxone on prolactin secretion from rat anterior pituitary glands in vitro.
Topics: Animals; Depression, Chemical; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Methionine; Female; Morphine; Naloxone; Narcotics; Organ Culture Techniques; Perfusion; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Effects of superfusion of morphine and enkephalins on the activity of single units in the spinal trigeminal nucleus and cuneate nucleus of cat.
Topics: Action Potentials; Animals; Cats; Electrophysiology; Enkephalin, Methionine; Enkephalins; Female; Male; Medulla Oblongata; Morphine; Naloxone; Trigeminal Nucleus, Spinal | 1986 |
Central and peripheral control of gastrointestinal and colonic motility by endogenous opiates in conscious dogs.
Topics: Animals; Central Nervous System; Colon; Dogs; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Gastrointestinal Motility; Peripheral Nerves | 1985 |
Interactions between enkephalin and dopamine in the control of locomotor activity in the rat: a new hypothesis.
Topics: Amphetamine; Animals; Dopamine; Drug Interactions; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Male; Motor Activity; Naloxone; Pimozide; Rats; Rats, Inbred Strains; Time Factors | 1985 |
No inotropic action of enkephalins or enkephalin derivatives on electrically-stimulated atria isolated from lean and obese rats.
Topics: Animals; Atrial Function; Carbachol; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Norepinephrine; Obesity; Rats; Rats, Inbred Strains; Rats, Zucker; Stimulation, Chemical | 1985 |
Asymmetric behavior induced by enkephalinergic agents in the basal ganglia.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Ganglia, Spinal; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1985 |
Neuronal sensitivity to opiate and opioid peptides in the bed nucleus of the stria terminalis. Effects of chronic treatment with morphine.
Topics: Amygdala; Animals; Dihydromorphine; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Evoked Potentials; Guinea Pigs; Hypothalamus, Middle; Male; Morphine; Neural Pathways; Neurons; Norepinephrine; Receptors, Opioid; Synaptic Transmission | 1984 |
Opioid control of the ruminant stomach motility: functional importance of mu, kappa and delta receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethylketocyclazocine; Fentanyl; Gastrointestinal Motility; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sheep; Stomach | 1984 |
An opiate system in the goldfish retina.
Topics: Action Potentials; Animals; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Goldfish; Neural Pathways; Neurotransmitter Agents; Retina | 1981 |
Noradrenergic terminal excitability: effects of opioids.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Frontal Lobe; Locus Coeruleus; Male; Morphine; Naloxone; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid | 1982 |
Modulatory interactions between enkephalin and catecholamines: anatomical and physiological substrates.
Topics: Animals; Antipsychotic Agents; Brain; Catecholamines; Drug Interactions; Electrophysiology; Enkephalin, Methionine; Enkephalins; Frontal Lobe; Histocytochemistry; Neurons; Rats; Tissue Distribution; Tyrosine 3-Monooxygenase | 1983 |
Stereospecificity of opiate-stimulated GTPase activity in brain.
Topics: Animals; Brain; Dextrorphan; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Etorphine; GTP Phosphohydrolases; In Vitro Techniques; Levorphanol; Narcotics; Phosphoric Monoester Hydrolases; Rats; Receptors, Opioid; Stereoisomerism | 1984 |
[Inhibitory effects of dynorphin on electric field stimulation induced contraction of blood vessels in vitro].
Topics: Animals; Dogs; Dynorphins; Ear; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; In Vitro Techniques; Mesenteric Arteries; Naloxone; Rabbits; Receptors, Opioid; Vasoconstriction | 1984 |
Peptides influence retinal ganglion cells.
Topics: Amphibians; Animals; Enkephalin, Methionine; Enkephalins; Iontophoresis; Neurons; Neurotensin; Peptide Fragments; Peptides; Photic Stimulation; Retina; Substance P | 1981 |
Serotonin and gamma-aminobutyric acid turnover after injection into the median raphe of substance P and D-ala-met-enkephalin amide.
Topics: Animals; Brain Stem; Cyclohexanecarboxylic Acids; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Hippocampus; Hydroxyindoleacetic Acid; Male; Raphe Nuclei; Rats; Serotonin; Substance P | 1982 |
Guanyl nucleotide interactions with opiate receptors in guinea pig brain and ileum.
Topics: Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Ileum; Kinetics; Male; Morphine Derivatives; Organ Specificity; Receptors, Opioid | 1980 |
Central effects of morphine, levorphanol, (-)-methadone and the opioid-like peptides beta-endorphin and D-alanine2- methionine enkephalinamide on urine volume outflow and electrolytes.
Topics: Animals; beta-Endorphin; Brain; Diuresis; Electrolytes; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Levorphanol; Male; Methadone; Morphine; Naloxone; Narcotics; Rats; Vasopressins | 1981 |
Comparative study on the effect of morphine and the opioid-like peptides in the vas deferens of rodents: species and strain differences, evidence for multiple opiate receptors.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Derivatives; Peptides; Rats; Receptors, Opioid; Species Specificity; Vas Deferens | 1981 |
Seasonal variation in the apparent number of binding sites for 3H-opioid agonists and antagonists.
Topics: Animals; Binding Sites; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Kinetics; Male; Mice; Morphinans; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Seasons | 1981 |
(D-Ala2, N-Val5), (D-Ala2, Met5) enkephalins and enkephalinamides. Correlation between biological activity and NMR features.
Topics: Animals; Biological Assay; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Magnetic Resonance Spectroscopy; Male; Mice; Protein Conformation; Receptors, Opioid; Structure-Activity Relationship; Vas Deferens | 1981 |
Evidence for distinct subcellular sites of opiate receptors. Demonstration of opiate receptors in smooth microsomal fractions isolated from rat brain.
Topics: Animals; Binding, Competitive; Brain; Cell Fractionation; Enkephalin, Methionine; Enkephalins; Guanylyl Imidodiphosphate; Kinetics; Microscopy, Electron; Microsomes; Naloxone; Rats; Receptors, Opioid; Subcellular Fractions | 1981 |
Comparison of the anticonvulsant effects of opioid peptides and etorphine in rats after icv administration.
Topics: Animals; Anticonvulsants; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Etorphine; Flurothyl; Male; Morphinans; Naloxone; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1981 |
Irreversible inactivation of the opiate receptors in the neuroblastoma x glioma hybrid NG108-15 by chlornaltrexamine.
Topics: Animals; Cyclic AMP; Enkephalin, Methionine; Enkephalins; Glioma; Hybrid Cells; Mice; Naloxone; Naltrexone; Neoplasms, Experimental; Neuroblastoma; Nitrogen Mustard Compounds; Prostaglandins E, Synthetic; Rats; Receptors, Opioid | 1981 |
Plasma norepinephrine, epinephrine and dopamine responses to intracerebral administration of a met-enkephalin analog, D-ala2-met-enkephalinamide, in rats.
Topics: Animals; beta-Endorphin; Cisterna Magna; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Epinephrine; Injections; Injections, Intra-Arterial; Male; Naloxone; Norepinephrine; Rats; Rats, Inbred Strains | 1981 |
High affinity binding of an enkephalin analog in the cerebral ganglion of the insect Leucophaea maderae (Blattaria).
Topics: Animals; Brain; Enkephalin, Methionine; Enkephalins; Female; Ganglia; Insecta; Male; Metamorphosis, Biological; Receptors, Opioid; Sex Factors | 1981 |
Classification of multiple morphine and enkephalin binding sites in the central nervous system.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Endorphins; Enkephalin, Methionine; Enkephalins; Kinetics; Morphine; Naloxone; Rats; Receptors, Opioid; Structure-Activity Relationship | 1981 |
A quantitative analysis of the shaking behavior induced in rats by beta-endorphin and [D-Ala2, Met5]enkephalinamide.
Topics: Animals; Behavior, Animal; beta-Endorphin; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains | 1982 |
Morphine-induced hyperthermia: lack of cross-tolerance with enkephalin analogs.
Topics: Animals; Body Temperature Regulation; Cats; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Morphine; Naloxone; Pentazocine; Receptors, Opioid | 1982 |
Calcium-opiate antagonism in the periaqueductal grey (PGA) region.
Topics: Animals; beta-Endorphin; Calcium; Cerebral Aqueduct; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Morphine; Nociceptors; Rats; Rats, Inbred Strains | 1981 |
Pulmonary opiate receptor activation evokes a cardiorespiratory reflex.
Topics: Animals; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Hemodynamics; Lung; Male; Myocardial Contraction; Peripheral Nerves; Rats; Rats, Inbred Strains; Receptors, Opioid; Reflex; Respiration; Time Factors | 1982 |
Opiate receptors from different tissue sources: solubilization and characterization.
Topics: Animals; Brain; Cell Line; Cerebral Cortex; Enkephalin, Methionine; Enkephalins; Glioma; Hybridomas; Hypothalamus; Male; Mice; Neuroblastoma; Rats; Rats, Inbred Strains; Receptors, Opioid; Solubility; Thalamus | 1982 |
Distribution of radioactivity in the spinal cord after intracerebroventricular and intravenous injection of radiolabeled opioid peptides in mice.
Topics: Analgesics; Animals; beta-Endorphin; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Muscles; Spinal Cord | 1982 |
Peptidergic regulation of stress-induced eating.
Topics: Animals; Appetite Depressants; Atropine; Bombesin; Carbachol; Cholecystokinin; Enkephalin, Methionine; Enkephalins; Feeding Behavior; Haloperidol; Humans; Isoproterenol; Male; Muscimol; Naloxone; Norepinephrine; Peptide Fragments; Peptides; Phentolamine; Quipazine; Rats; Rats, Inbred Strains; Sincalide; Stress, Psychological | 1982 |
Opioids increase laryngeal resistance and motoneuron activity in the recurrent laryngeal nerve.
Topics: Animals; Biguanides; Chemoreceptor Cells; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Laryngeal Nerves; Larynx; Male; Morphine; Motor Neurons; Rats; Receptors, Opioid; Recurrent Laryngeal Nerve; Reflex | 1982 |
Modulation of dopamine release in rat striatal slices by delta opiate agonists.
Topics: Animals; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Tetrodotoxin | 1982 |
Characterization of the dopamine stimulated adenylate cyclase in the pedal ganglia of Mytilus edulis: interactions with etorphine, beta-endorphin, DALA, and methionine enkephalin.
Topics: Adenylyl Cyclases; Animals; beta-Endorphin; Bivalvia; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Etorphine; Ganglia; Kinetics; Morphinans | 1981 |
Down regulation of enkephalin (delta) receptors. Demonstration in membrane-bound and solubilized receptors.
Topics: Alkaloids; Animals; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Etorphine; Glioma; Hybrid Cells; In Vitro Techniques; Morphine; Neuroblastoma; Rats; Receptors, Opioid; Solubility | 1982 |
Further evidence for an opioid receptor complex.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; In Vitro Techniques; Rats; Receptors, Opioid | 1983 |
Multi-dimensional analyses of behavior in mice treated with morphine, endorphins and [des-tyrosine1]-gamma-endorphin.
Topics: Animals; Behavior, Animal; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Male; Mice; Morphine; Naltrexone; Peptide Fragments | 1983 |
Adrenergic mediation of the intestinal antisecretory action of opiates administered into the central nervous system.
Topics: Animals; Blood Pressure; Brain; Cholera Toxin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Hydrogen-Ion Concentration; In Vitro Techniques; Injections, Intraventricular; Intestinal Mucosa; Male; Morphine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Tyramine | 1984 |
Pharmacological analysis of shaking behavior induced by enkephalins, thyrotropin-releasing hormone or serotonin in rats: evidence for different mechanisms.
Topics: Animals; Behavior, Animal; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Thyrotropin-Releasing Hormone | 1983 |
Analgesic effects of enkephalin analogs in rats.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Male; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Involvement of endogenous enkephalins in the mouse 'behavioral despair' test.
Topics: Aminopeptidases; Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Motor Activity; Naloxone; Protease Inhibitors; Thiorphan; Tiopronin | 1984 |
The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat.
Topics: Animals; Cats; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Morphine; Naloxone; Oligopeptides; Reflex; Thiorphan; Tiopronin; Urination | 1984 |
The stinging response of the honeybee: effects of morphine, naloxone and some opioid peptides.
Topics: Animals; Bees; Behavior, Animal; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Insect Bites and Stings; Morphine; Naloxone | 1983 |
D-ala2-methionine-enkephalinamide self-administration in the morphine-dependent rat.
Topics: Animals; Drug Administration Schedule; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Humans; Injections, Intraventricular; Morphine Dependence; Rats; Self Administration; Substance Withdrawal Syndrome | 1980 |
Characterization of the respiratory activity of (D-Ala2)methionine-enkephalinamide.
Topics: Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Rats; Respiration; Respiratory Center; Time Factors | 1981 |
[Implication of enkephalins in central cardiovascular regulation in the rat].
Topics: Animals; Autonomic Nervous System; Blood Pressure; Diprenorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Heart Rate; Hypertension; Injections, Spinal; Naloxone; Oxygen; Rats; Rats, Inbred Strains; Respiration | 1982 |
Naloxone blocks the effect of 5-hydroxy-tryptophan on passive avoidance learning in rats: implication of endogenous opiod peptides.
Topics: 5-Hydroxytryptophan; Animals; Avoidance Learning; Behavior, Animal; Clorgyline; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Rats; Serotonin | 1981 |
Effects of intraventricular morphine and enkephalins on locomotor activity in nondependent, morphine-dependent and postdependent rats.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Rats; Time Factors | 1981 |
The behavioural effects of enkephalin analogues injected into the ventral tegmental area and globus pallidus.
Topics: Animals; Behavior, Animal; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Flupenthixol; Globus Pallidus; Male; Motor Activity; Naloxone; Organ Specificity; Rats; Tegmentum Mesencephali | 1981 |
In vivo potentiation of [D-Ala2]Met-enkephalin amide central effects after administration of an enkephalinase inhibitor.
Topics: Animals; Brain; Dipeptides; Drug Synergism; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains | 1981 |
Depression of learned thermoregulatory behavior by central injection of opioids in cats.
Topics: Animals; Avoidance Learning; Body Temperature Regulation; Cats; Conditioning, Operant; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Morphine; Motor Activity; Pentazocine | 1982 |
Opiate alkaloids antagonize postsynaptic glycine and GABA responses: correlation with convulsant action.
Topics: Animals; Cells, Cultured; Dextrorphan; Enkephalin, Methionine; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Levorphanol; Mice; Morphine; Naloxone; Narcotics; Neural Inhibition; Neurons; Seizures; Spinal Cord; Synapses | 1982 |
Effects of (D-alanine2, methionine5) enkephalinamide on the release of acetylcholine and noradrenaline from brain slices and isolated nerve terminals.
Topics: Acetylcholine; Animals; Brain; Endorphins; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Membrane Potentials; Norepinephrine; Potassium; Rats; Synaptosomes | 1982 |
Reward produced by microinjection of (D-Ala2),Met5-enkephalinamide into the ventral tegmental area.
Topics: Animals; Conditioning, Operant; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Rats; Reward; Tegmentum Mesencephali | 1982 |
Effects of intraventricular morphine and enkephalins on schedule-controlled behavior in nondependent, morphine-dependent and postdependent rats.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Injections, Intraventricular; Male; Morphine; Morphine Dependence; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1981 |
Central neuropharmacology of D-Ala2-Met-enkephalinamide and its interactions with taurine in rats.
Topics: Analgesia; Animals; Catatonia; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Humans; Leucine; Male; Rats; Rats, Inbred Strains; Seizures; Taurine | 1981 |
Contraversive circling and facilitation of the perioral biting reflex by injection of substance P or D-Ala2-Met-encephalinamide into the substantia nigra.
Topics: Animals; Appetitive Behavior; Dominance, Cerebral; Endorphins; Enkephalin, Methionine; Enkephalins; Humans; Male; Muscimol; Naloxone; Predatory Behavior; Rats; Rats, Inbred Strains; Reflex; Stereotyped Behavior; Substantia Nigra | 1982 |
Spreading depression induced by microinjection of enkephalins into the hippocampus and neocortex.
Topics: Animals; Cerebral Cortex; Cortical Spreading Depression; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Hippocampus; Male; Membrane Potentials; Naloxone; Rats | 1981 |
Morphine and delta-opiate agonists locally stimulate in vivo dopamine release in cat caudate nucleus.
Topics: Animals; Cats; Caudate Nucleus; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Morphine; Naloxone | 1981 |
Effects of taurine and gamma-aminobutyric acid on akinesia and analgesia induced by D-Ala2-Met-enkephalinamide in rats.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Kinetics; Leucine; Male; Movement; Rats; Taurine | 1980 |
Accurate measurement of intestinal transit in the rat.
Topics: Analysis of Variance; Animals; Capsaicin; Catheters, Indwelling; Chromium Radioisotopes; Duodenum; Enkephalin, Methionine; Enkephalins; Female; Hexamethonium Compounds; Intestine, Small; Neostigmine; Rats; Rats, Inbred Strains; Regression Analysis; Sodium Chloride; Tissue Distribution | 1981 |
Enhanced analgesic activity of liposomised Met-enkephalin analogue.
Topics: Analgesia; Animals; Endorphins; Enkephalin, Methionine; Enkephalins; Liposomes; Mice; Naloxone | 1981 |
Effects of intraventricular beta-endorphin and D-ALA2-methionine-enkephalinamide on behaviour, spectrum power of electrocortical activity and body temperature in chicks.
Topics: Animals; Behavior, Animal; Body Temperature; Chickens; Electroencephalography; Endorphins; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Time Factors | 1980 |
Naloxone-reversible effects of d-Ala2-Met5-enkephalinamide-induced behavioral activity in rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Male; Morphine; Motor Activity; Naloxone; Rats | 1980 |
Delta opioid agonists inhibit proliferation of highlypurified murine CD4+ and CD8+ T-cells.
Topics: Analgesics; Animals; CD4 Antigens; CD8 Antigens; Cell Division; Cells, Cultured; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Female; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; T-Lymphocytes | 1995 |
Action of opioid peptides on the rat adrenal cortex: stimulation of steroid secretion through a specific mu opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenal Cortex; Aldosterone; Analgesics; Animals; beta-Endorphin; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Male; Opioid Peptides; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1995 |
Mesoaccumbens dopamine-opiate interactions in the control over behaviour by a conditioned reinforcer.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesics; Animals; Behavior, Animal; Conditioning, Operant; Dextroamphetamine; Dopamine Agonists; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Ergolines; Injections; Male; Nucleus Accumbens; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Tegmentum Mesencephali | 1994 |
Schistosoma mansoni: an enkephalinergic system that may participate in internal and host-parasite signaling.
Topics: Animals; beta-Endorphin; Binding, Competitive; Biomphalaria; Cell Communication; Cricetinae; Enkephalin, Methionine; Enkephalins; Host-Parasite Interactions; Naloxone; Radioimmunoassay; Receptors, Opioid; Schistosoma mansoni; Signal Transduction; Trypsin; Trypsin Inhibitors | 1993 |
Biochemical evidence of functional interaction between mu- and delta-opioid receptors in SK-N-BE neuroblastoma cell line.
Topics: Adenylyl Cyclases; Analgesics; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Humans; Membrane Proteins; Neuroblastoma; Receptors, Opioid, delta; Receptors, Opioid, mu; Time Factors; Tumor Cells, Cultured | 1996 |
Predatory aggression induced by hypothalamic stimulation: modulation by midbrain periaqueductal gray (PAG).
Topics: Aggression; Animals; Cats; Electric Stimulation; Enkephalin, Methionine; Enkephalins; Hypothalamus; Male; Microinjections; Periaqueductal Gray; Predatory Behavior; Rats; Reference Values; Statistics as Topic | 1995 |
Naltrindole sensitive delta 2 opioid receptor mediates invertebrate immunocyte activation.
Topics: Animals; Bivalvia; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Immune System; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta | 1995 |
Role of midbrain ventro-lateral tegmental area (VTA) enkephalinergic mechanisms in the facilitation of hypothalamically-induced predatory attack behaviour.
Topics: Animals; Cats; Drug Interactions; Electric Stimulation; Electrodes, Implanted; Enkephalin, Methionine; Enkephalins; Female; Hypothalamus; Male; Microinjections; Naloxone; Narcotic Antagonists; Predatory Behavior; Rats; Staining and Labeling; Ventral Tegmental Area | 1997 |
Distinct differences between morphine- and [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin-mu-opioid receptor complexes demonstrated by cyclic AMP-dependent protein kinase phosphorylation.
Topics: Analgesics, Opioid; Antibody Specificity; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Enzyme Inhibitors; Indoles; Morphine; Neuroblastoma; Neurons; Phosphorylation; Precipitin Tests; Pyrroles; Receptors, Opioid, mu; Tumor Cells, Cultured | 1998 |
Vulnerability to stressor-induced disturbances in self-stimulation from the dorsal and ventral A10 area: differential effects of intraventricular D-Ala2-Met5-enkephalinamide, D-Ala2, N-Me-Phe4, Gly-Ol5-enkephalin, and D-Pen2, D-Pen5-enkephalin administrat
Topics: Animals; Electric Stimulation; Electroshock; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Foot; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Receptors, Opioid, delta; Receptors, Opioid, mu; Self Stimulation; Stress, Physiological; Tegmentum Mesencephali; Time Factors | 1998 |
Effects of peptidase inhibitors, [D-Ala2, Met5]-enkephalinamide and antiserum to methionine-enkephalin microinjected into the caudal periaqueductal gray on morphine withdrawal in rats.
Topics: Animals; Enkephalin, Methionine; Enkephalins; Immune Sera; Male; Microinjections; Morphine; Morphine Dependence; Naloxone; Periaqueductal Gray; Protease Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance Withdrawal Syndrome | 1998 |
Disturbances in behavior and cortical enkephalin gene expression during the anticipation of ethanol in rats characterized as high drinkers.
Topics: Alcohol Drinking; Animals; Anticipation, Psychological; Behavior, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Ethanol; Exploratory Behavior; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 2012 |
Hypothalamic peptides controlling alcohol intake: differential effects on microstructure of drinking bouts.
Topics: Alcohol Drinking; Animals; Enkephalin, Methionine; Enkephalins; Galanin; Injections, Intraventricular; Intracellular Signaling Peptides and Proteins; Male; Neuropeptides; Orexins; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley | 2014 |