enkephalin, leucine and enkephalin, ser(2), leu(5), thr(6)-

enkephalin, leucine has been researched along with enkephalin, ser(2), leu(5), thr(6)- in 209 studies

Research

Studies (209)

Timeframe	Studies, this research(%)	All Research%
pre-1990	64 (30.62)	18.7374
1990's	118 (56.46)	18.2507
2000's	20 (9.57)	29.6817
2010's	7 (3.35)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Grossman, A; Hucks, D; Joel, SP; McLoughlin, L; Patel, N; Rees, LH; Slevin, ML; Thompson, PI	1
Borsodi, A; Búzás, B; Cavagnero, S; Hruby, VJ; Tóth, G	1
McDonald, JS; Rattan, AK; Tejwani, GA	1
Childers, SR; Fleming, L; Konkoy, C; Marckel, D; Pacheco, M; Sexton, T; Ward, S	1
Olianas, MC; Onali, P	1
Il'ina, AD; Iukhananov, RIu; Klodt, PM; Varfolomeev, SD; Zaĭtsev, SV	1
Fan, LQ; Hiller, JM; Ofri, D; Simon, EJ	1
Portoghese, PS; Sofuoglu, M; Takemori, AE	1
Crook, TJ; Hill, RG; Kitchen, I	1
Childers, SR; Nijssen, PC; Sexton, T	1
Chung, NN; Lemieux, C; Nguyen, TM; Schiller, PW; Weltrowska, G; Wilkes, BC	1
Barnard, EA; Demoliou-Mason, C; Richardson, A	1
Hiller, JM; Simon, EJ; Stein, EA	1
Bowen, WD; Jiang, Q; Mosberg, HI; Porreca, F; Portoghese, PS; Sultana, M; Takemori, AE	1
Bhargava, HN; Gulati, A	1
Bunn, SJ	1
Gudehithlu, KP; McDonald, JS; Rattan, AK; Tejwani, GA	1
Bhargava, HN; Gulati, A; Rahmani, NH	1
Bodnar, R; Pasternak, GW; Paul, D	1
Barfolomeev, SD; Kurochkin, IN; Melikhova, EV; Sukhovlin, TK	1
Schmidt, PF; Schomburg, ED; Steffens, H	1
Bunn, SJ; Dunkley, PR	1
Bodnar, RJ; Kepler, KL; Kest, B; Pasternak, GW; Paul, D; Standifer, KM	1
Cohen, Y; Jacquot, C; Orosco, M; Robert, JJ; Rouch, C	2
Helme, RD; Khalil, Z	2
Billington, CJ; Grace, M; Levine, AS; Portoghese, PS	1
Henderson, G; Rogers, H	1
Hanissian, SH; Tejwani, GA	1
La Regina, A; Petrillo, P; Sbacchi, M; Tavani, A	1
Boon, F; Cain, DP; Corcoran, ME	1
Krekhnov, BV; Kurochkin, IN; Skliankina, OA; Varfolomeev, SD; Varfolomeeva, AD; Zaĭtsev, SV	1
Fan, LQ; Hiller, JM; Simon, EJ	3
Andreou, A; Angelopoulos, EK; Koutsoukos, E; Loukas, S; Maillis, A; Stefanis, C; Zioudrou, C	1
Clark, MJ; Medzihradsky, F; Nordby, GL	1
deGroat, WC; Hisamitsu, T; Nagel, J; Roppolo, JR; Thor, KB; Tuttle, P	1
Basbaum, AI; Levine, JD; Perry, F; Taiwo, YO	1
DeLeon-Jones, FA; Fields, JZ; Lee, JM; Ritzmann, RF; Steece, KA	1
Billington, CJ; Gosnell, BA; Grace, M; Levine, AS	1
Bidlack, JM; Selley, DE	1
Bhargava, HN; Gulati, A; Ramarao, P	2
Belleney, J; Fournié-Zaluski, MC; Gacel, G; Maigret, B; Roques, BP	1
Bodnar, RJ; Gistrak, MA; Pasternak, GW; Paul, D	1
de Castiglione, R; Guglietta, A; Lazarus, LH; Wilson, WE	1
Bowen, WD; Herkenham, M; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB	1
Hoffman, PL; Khatami, S; Salafsky, B; Shibuya, T	1
Bockaert, J; Eybalin, M; Pujol, R	1
Gauthier, S; Magnan, J; Pilapil, C; Quirion, R; Welner, S	1
Childers, SR	1
Daugé, V; Delay-Goyet, P; Gacel, G; Roques, BP; Zajac, JM	1
Clark, MJ; Medzihradsky, F	1
Bhargava, HN; Collins, BJ; Rapaka, RS; Renugopalakrishnan, V	1
Crema, G; Gioannini, TL; Hiller, JM; Simon, EJ	1
Smith, CB	1
Cox, BM; Puttfarcken, PS; Werling, LL	1
Bhargava, HN; Rapaka, RS; Renugopalakrishnan, V	1
Barnard, EA; Demoliou-Mason, CD; Wong, YH	1
Bodnar, RJ; Lee, SJ; Pasternak, GW; Williams, CL	1
Dickenson, AH; Roques, BP; Sullivan, AF	1
Ho, BY; Naeseth, JS; Portoghese, PS; Takemori, AE	1
Gosnell, BA; Levine, AS; Morley, JE	1
Jensen, TS; Yaksh, TL	1
Gosnell, BA; Grace, M; Levine, AS	1
Chavkin, C; Mailheau, S; Neumaier, JF	1
Chavkin, C; Neumaier, JF; Swearengen, E	1
Clark, JA; Houghten, R; Pasternak, GW	1
Johnson, DR; Oleson, DR	1
Burke, TR; Danks, JA; Herkenham, M; Jacobson, AE; Rice, KC; Rothman, RB	1
Boudouresque, F; Bourhim, N; Cantau, P; Castanas, E; Giraud, P; Oliver, C	2
Coletti-Previero, MA; Descomps, B; Martin, JL; Roques, BP	1
Portoghese, PS; Takemori, AE	1
Carter, DA; Lightman, SL	1
Lemieux, C; Maziak, LA; Nguyen, TM; Schiller, PW	1
Dzoljic, MR; Haffmans, J; Heiligers, J; Saxena, PR	1
Snead, OC	1
Brown, SR; Cox, BM; Puttfarcken, P; Werling, LL	1
Aceto, MD; Bajwa, BS; Harris, LS; Jacobson, AE; Klee, WA; Lessor, RA; May, EL; Rice, KC; Smith, CB; Streaty, RA	1
Clark, JA; Hruby, VJ; Itzhak, Y; Pasternak, GW; Yamamura, HI	1
Bhargava, HN; Das, S	2
Itzhak, Y; Pasternak, GW	1
Akil, H; Khachaturian, H; Lewis, ME; Mansour, A; Watson, SJ	1
Heyman, JS; Mosberg, HI; Omnaas, JR; Porreca, F; Vaught, JL	1
Geladopoulos, T; Sakellaridis, N; Vernadakis, A	1
Dzoljic, MR; Haffmans, J	2
Belknap, JK; Laursen, SE	1
Pert, CB; Rothman, RB; Schumacher, UK	1
Champagnat, J; Denavit-Saubie, M; Gacel, G; Morin-Surun, MP; Roques, BP	1
David, M; Gacel, G; Meunier, JC; Moisand, C; Morgat, JL; Roques, BP	1
Flórez, J; Pazos, A	2
Burks, TF; Galligan, JJ; Gee, K; Hruby, VJ; Hurst, R; Mosberg, HI; Yamamura, HI	1
Boudinot, E; Champagnat, J; Denavit-Saubie, M; Gacel, G; Morin-Surun, MP; Roques, BP	1
De Kloet, R; Dzoljic, MR; Haffmans, J	1
de Groat, WC; Hisamitsu, T	1
Fukushima, N; Hayashi, C; Iwamura, T; Misu, Y; Miyamae, T; Sasaki, Y; Ueda, H; Watanabe, S	1
Cucumel, K; Cupo, A	1
Chiappinelli, VA; Feng, C; McMahon, LL; Wolf, KM; Yum, L	1
Fukushima, N; Hayashi, C; Katayama, T; Misu, Y; Miyamae, T; Ueda, H	1
Cote, T; Cox, BM; Kiang, JG; Tang, T	1
de Waele, JP; Gianoulakis, C; Kiianmaa, K	1
Cupo, A; Garreau, I; Pejoan, C; Piot, JM; Zhao, Q	1
Dragatsis, I; Gerozissis, K; Papazafiri, P; Zioudrou, C	1
Côté, TE; Cox, BM; Kiang, JG; Tang, T	1
Bélisle, S; Bellabarba, D; Gallo-Payet, N; Lehoux, JG; Petit, A	1
Coupar, IM; Hancock, DL	1
Angelopoulos, E; Koutsoukos, E; Maillis, A; Stefanis, C; Zioudrou, C	1
Barannik, VL; Lishmanov, IuB; Maslov, LN; Ugdyzhekova, DS	1
Fukushima, N; Misu, Y; Miyamae, T; Ueda, H	2
Il'Ina, AD; Klodt, PM; Maisky, AI; Zaitsev, SV	1
Búzás, B; Cox, BM; Izenwasser, S	1
Barnard, EA; Benyhe, S; Borsodi, A; Simon, J; Wollemann, M	1
Davis, T; Shah, S; Yoburn, BC	1
Erikson, LJ; Evans, C; Law, PY; Loh, HH; McGinn, TM; Wick, MJ	1
Crook, TJ; Hill, RG; Kitchen, I; Muhammad, BY	1
Bell, GI; Kong, H; Raynor, K; Reisine, T; Takeda, J; Yano, H	1
Barg, J; Belcheva, M; Burke, WJ; Chung, HD; Coscia, CJ; Ho, A; Rowinski, J; Schmidt, CA	1
Cheĭdo, MA; Idova, GV	4
Loukas, S; Mercouris, M; Panetsos, F; Zioudrou, C	1
Breivogel, CS; Childers, SR; Selley, DE	2
Chang, KJ; Comer, SD; De Costa, BR; Hoenicke, EM; McNutt, RW; Mosberg, HI; Sable, AI; Woods, JH	1
Chakrabarti, S; Portoghese, PS; Sultana, M; Takemori, AE	1
Búzás, B; Cox, BM; Izenwasser, S; Portoghese, PS	1
Lanthorn, TH; Watson, GB	1
Miyamoto, Y; Portoghese, PS; Takemori, AE	2
Davis, TP; Haaseth, RC; Horan, PJ; Hruby, VJ; Lipkowski, A; Misicka, A; Porreca, F; Weber, SJ; Wild, KD; Yamamura, HI	1
Coupar, IM	1
Howells, RD; Jin, J; Shahrestanifar, M; Wang, WW	1
Howells, RD; Shahrestanifar, M; Wang, WW	1
Hruby, VJ; Kovelowski, CJ; Nichols, ML; Ossipov, MH; Porreca, F	1
Endoh, T; Suzuki, T	1
Cheido, M; Devoino, L; Idova, G	1
Maliukova, IV; Metaksa, EE; Zakharova, LA	1
Cox, BM; Stevens, BA; Tang, T	1
Fujimoto, JM; Rady, JJ	1
Fukushima, N; Hayashi, C; Katayama, T; Misu, Y; Ueda, H	1
Bakogeorgou, E; Castanas, E; Hatzoglou, A	1
Kampine, JP; Mizoguchi, H; Narita, M; Tseng, LF	2
Buzas, B; Cox, BM; Rosenberger, J	2
Dragatsis, I; Georgoussi, Z; Konidakis, G; Megaritis, G; Merkouris, M; Milligan, G; Zioudrou, C	1
Christensen, CB; Christrup, LL; Kristensen, K; Nielsen, LC	1
Kodama, H; Kondo, M; Motoyama, S; Nose, T; Shimohigashi, Y; Yasunaga, T	1
Fan, LQ; Hiller, JM	1
Fujimoto, J; Ho, BY; Holmes, BB; Zhao, J	1
Cheng, Z; Pei, G; Wang, C; Wu, Y; Zhou, D; Zhu, X	1
Billington, CJ; Kotz, CM; Levine, AS	1
Ingram, S; McCleskey, EW; Wilding, TJ; Williams, JT	1
Márquez, CD; Smith, PC; Weintraub, ST	1
Blake, AD; Bot, G; Li, S; Reisine, T	2
Childers, SR; Sim, LJ	1
Lishmanov, IuB; Maslov, LN; Ugdyzhekova, DS	1
Jankowska, E; Schomburg, ED	1
Campana, G; Di Toro, R; Murari, G; Sciarretta, V; Spampinato, S	1
Clark, MJ; Liu, XY; Medzihradsky, F; Remmers, AE	1
Kramer, HK; Simon, EJ	2
Liu, H; Mazarati, A; Wasterlain, C	1
Chen, J; Chi, ZQ; Li, GE; Pei, G; Wang, CH; Zhou, DH	1
Bebiakova, NA; Mikhaĭlova, SD; Semushkina, TM; Storozhakov, GI	1
Fujimoto, JM; Holmes, BB; Rady, JJ	1
Bebiakova, NA; Mikhaĭlova, SD; Semushkina, TM; Sokolov, AV; Storozhakov, GI	1
Cao, XD; Cui, DF; Li, MY; Qi, ZW; Wu, GC; Xu, SF; Zhang, XL; Zhu, CB	1
Malyukova, IV; Molotkovskaya, IM; Zakharova, LA	1
Bakalkin, G; Derjabin, V; Hauser, KF; Nazarevskaja, G; Reznikov, K; Trunova, Y	1
Osadchiĭ, OE; Pokrovskiĭ, VM	1
Gafni, M; Keren, O; Sarne, Y	1
Borsodi, A; Medzihradszky, K; Orosz, G; Szatmári, I	1
Chatzaki, E; Dermitzaki, E; Gravanis, A; Margioris, AN	1
Cox, SL; Schelb, V; Starke, K; Trendelenburg, AU	1
Inoue, M; Ueda, H	1
Andria, ML; Esposito, DH; Hiller, JM; Kramer, HK; Kushner, SA; Simon, EJ	1
Glushchenko, NV; Mikhailova, SD; Semushkina, TM; Storozhakov, GI	1
Campbell, WB; Fujimoto, JM; Rady, JJ	1
Brown, DR; Poonyachoti, S; Portoghese, PS	1
Lishmanov, AY; Maslov, LN; Rebrova, TY; Tam, SV	1
Lishmanov, IuB; Maslov, LN; Rebrova, TIu; Tam, SV	1
Schomburg, ED; Steffens, H; Wada, N	1
Gross, GJ; Krylatov, AV; Lishmanov, IuB; Maslov, LN; Naryzhnaia, NV; Stephano, JB	1
Andria, ML; Haddad, LB; Hanna, K; Kramer, HK; Onoprishvili, I; Sheinkman, K; Simon, EJ	1
Martin-Kleiner, I	1
Gross, GJ; Krylatov, AV; Lasukova, TV; Lishmanov, YB; Maslov, LN; Stefano, GB	1
Burda, IuE; Liashev, IuD	1
Gross, GJ; Lishmanov, YB; Maslov, LN; Solenkova, NV; Stefano, GB; Tam, SW	1
Konoplya, AI; Sever'yanova, LA; Shveinov, IA; Smakhtin, MY	1
Cools, AR; Hirose, N; Koshikawa, N; Murakawa, K; Nagase, H; Oi, Y; Suzuki, T; Takada, K	1
Bernard, D; Coop, A; MacKerell, AD	1
Agalou, A; Georganta, EM; Georgoussi, Z	1
Dibaj, P; Schomburg, ED; Steffens, H	1
Lyashev, YD; Solin, AV	3
Lyashev, AY; Lyashev, YD; Solin, AV	1
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L	1
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A	1

Reviews

1 review(s) available for enkephalin, leucine and enkephalin, ser(2), leu(5), thr(6)-

Article	Year
Opioid receptor mechanisms in the rat hippocampus. NIDA research monograph, 1988, Volume: 82 Topics: Animals; Dynorphins; Electrophysiology; Enkephalin, Leucine; gamma-Aminobutyric Acid; Hippocampus; Naloxone; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta	1988

Other Studies

208 other study(ies) available for enkephalin, leucine and enkephalin, ser(2), leu(5), thr(6)-

Article	Year
Explanation at the opioid receptor level for differing toxicity of morphine and morphine 6-glucuronide. British journal of cancer, 1992, Volume: 65, Issue:1 Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Morphine; Morphine Derivatives; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Subcellular Fractions	1992
Synthesis and binding characteristics of the highly delta-specific new tritiated opioid peptide, [3H]deltorphin II. Life sciences, 1992, Volume: 50, Issue:14 Topics: Analgesics; Animals; Benzeneacetamides; Brain; Cell Membrane; Dihydromorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indicators and Reagents; Isotope Labeling; Kinetics; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium	1992
Role of spinal opioid receptors in the antinociceptive interactions between intrathecal morphine and bupivacaine. Anesthesia and analgesia, 1992, Volume: 74, Issue:5 Topics: Analgesics; Animals; Bupivacaine; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Leucine; Injections, Spinal; Male; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord	1992
Opioid and cannabinoid receptor inhibition of adenylyl cyclase in brain. Annals of the New York Academy of Sciences, 1992, Jun-28, Volume: 654 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Imidodiphosphate; Analgesics; Animals; Brain; Cannabinoids; Cells, Cultured; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Neurons; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid; RNA, Messenger	1992
Characterization of opioid receptors mediating stimulation of adenylate cyclase activity in rat olfactory bulb. Molecular pharmacology, 1992, Volume: 42, Issue:1 Topics: Adenylyl Cyclases; Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Enzyme Activation; Male; Narcotic Antagonists; Olfactory Bulb; Oligopeptides; Opioid Peptides; Rats; Rats, Inbred Strains; Receptors, Opioid	1992
[Heterogeneity of mu- and delta-opioid active sites in the mouse cerebral cortex. Selective increase in the affinity of a superhigh affinity delta-site during long-term administration of morphine]. Biokhimiia (Moscow, Russia), 1992, Volume: 57, Issue:8 Topics: Animals; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Male; Mice; Mice, Inbred C57BL; Morphine; Receptors, Opioid, delta; Receptors, Opioid, mu; Substrate Specificity	1992
Lesioning of the nucleus basalis of Meynert has differential effects on mu, delta and kappa opioid receptor binding in rat brain: a quantitative autoradiographic study. Brain research, 1992, May-29, Volume: 581, Issue:2 Topics: Animals; Autoradiography; Brain; Cerebral Cortex; Choline O-Acetyltransferase; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Male; Organ Specificity; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reference Values; Substantia Innominata; Tritium	1992
delta-Opioid receptor binding in mouse brain: evidence for heterogeneous binding sites. European journal of pharmacology, 1992, Jun-05, Volume: 216, Issue:2 Topics: Animals; Binding, Competitive; Brain Chemistry; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Membranes; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta	1992
Effects of the delta-opioid receptor antagonist naltrindole on antinociceptive responses to selective delta-agonists in post-weanling rats. British journal of pharmacology, 1992, Volume: 107, Issue:2 Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indoles; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, delta	1992
Opioid-inhibited adenylyl cyclase in rat brain membranes: lack of correlation with high-affinity opioid receptor binding sites. Journal of neurochemistry, 1992, Volume: 59, Issue:6 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Cell Membrane; Colforsin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Male; Naloxone; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium; Sodium Chloride; Sodium Fluoride	1992
Conformationally restricted deltorphin analogues. Journal of medicinal chemistry, 1992, Oct-16, Volume: 35, Issue:21 Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Molecular Sequence Data; Oligopeptides; Protein Conformation; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens	1992
Guanine nucleotide-binding protein-coupled and -uncoupled states of opioid receptors and their relevance to the determination of subtypes. Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-01, Volume: 89, Issue:21 Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Cell Membrane; Cerebellum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Etorphine; Female; GTP-Binding Proteins; Guinea Pigs; Humans; Kinetics; Ligands; Placenta; Pregnancy; Prosencephalon; Protein Binding; Pyrrolidines; Rats; Receptors, Opioid	1992
Effects of stress on opioid receptor binding in the rat central nervous system. Neuroscience, 1992, Volume: 51, Issue:3 Topics: Amino Acid Sequence; Analgesics; Animals; Central Nervous System; Electroshock; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Stress, Psychological; Water Deprivation	1992
Differential antagonism of opioid delta antinociception by [D-Ala2,Leu5,Cys6]enkephalin and naltrindole 5'-isothiocyanate: evidence for delta receptor subtypes. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Intraventricular; Isothiocyanates; Male; Mice; Mice, Inbred ICR; Morphinans; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Thiocyanates	1991
The effect of morphine tolerance-dependence and abstinence on mu, delta, and kappa opiate receptors of discrete brain regions and spinal cord of the rat. NIDA research monograph, 1990, Volume: 105 Topics: Animals; Brain Chemistry; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; Morphine; Morphine Dependence; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome	1990
Localisation and pharmacological characterisation of [3H]bremazocine binding in the bovine adrenal medulla. Neuroscience letters, 1991, Apr-29, Volume: 125, Issue:2 Topics: Adrenal Medulla; Animals; Autoradiography; Benzomorphans; Binding, Competitive; Cattle; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Receptors, Opioid; Receptors, Opioid, kappa; Tritium	1991
Modulation of mu, kappa and delta opioid receptors in the rat brain by isoflurane and enflurane. Neuropharmacology, 1991, Volume: 30, Issue:6 Topics: Analgesics; Animals; Brain Chemistry; Cerebral Cortex; Enflurane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Isoflurane; Male; Mesencephalon; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord	1991
Differences in the binding of [3H][D-Ser2,Thr6]leucine-enkephalin and [3H][D-Pen2,D-Pen5]enkephalin to brain membranes of morphine tolerant-dependent rats. European journal of pharmacology, 1991, Sep-24, Volume: 202, Issue:3 Topics: Analgesics; Animals; Brain; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Ligands; Male; Morphine; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord; Substance-Related Disorders	1991
Synergistic analgesic interactions between the periaqueductal gray and the locus coeruleus. Brain research, 1991, Sep-06, Volume: 558, Issue:2 Topics: Analgesics; Animals; Enkephalin, Leucine; Ethylketocyclazocine; Locus Coeruleus; Male; Microinjections; Morphine; Narcotic Antagonists; Periaqueductal Gray; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reticular Formation; Stereotaxic Techniques	1991
[Periodic and aperiodic oscillations in neuropeptide-binding receptors in cultured cells]. Doklady Akademii nauk SSSR, 1991, Volume: 320, Issue:2 Topics: Animals; Cells, Cultured; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Kinetics; Neuropeptides; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta	1991
Limitedly selective action of a delta-agonistic leu-enkephalin on the transmission in spinal motor reflex pathways in cats. The Journal of physiology, 1991, Volume: 442 Topics: Afferent Pathways; Analgesics; Animals; Cats; Enkephalin, Leucine; Injections, Intravenous; Naloxone; Neural Inhibition; Nociceptors; Reflex, Monosynaptic; Spinal Cord; Synaptic Transmission	1991
Opioid inhibition of nicotine-induced 45Ca2(+)-uptake into cultured bovine adrenal medullary cells. Biochemical pharmacology, 1991, Mar-01, Volume: 41, Issue:5 Topics: Adrenal Medulla; Animals; Benzomorphans; Calcium; Cattle; Cells, Cultured; Chromaffin System; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Nicotine; Oligopeptides	1991
Gender effects and central opioid analgesia. Pain, 1991, Volume: 45, Issue:1 Topics: Analgesics, Opioid; Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Female; Injections, Intraventricular; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seminal Vesicles; Sensory Thresholds; Sex Characteristics; Uterus	1991
Effects of dexfenfluramine and opioid peptides, alone or in combination, on food intake and brain serotonin turnover in rats. Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:4 Topics: Animals; beta-Endorphin; Brain; Drug Interactions; Dynorphins; Eating; Endorphins; Enkephalin, Leucine; Female; Fenfluramine; Naltrexone; Rats; Rats, Inbred Strains; Serotonin	1991
Modulation of a peripheral inflammatory response to substance P by locally administered opioid receptor agonists. Neuropeptides, 1990, Volume: 17, Issue:1 Topics: Administration, Topical; Amino Acid Sequence; Animals; Blister; Capillary Permeability; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Inflammation; Male; Molecular Sequence Data; Naloxone; Oligopeptides; Perfusion; Peripheral Nerves; Rats; Skin; Substance P; Vasodilation	1990
Effects of serotonin and opioid agonists on tachyphylaxis to SP-induced vasodilatation. Annals of the New York Academy of Sciences, 1991, Volume: 632 Topics: Analgesics; Animals; Blister; Enkephalin, Leucine; Methoxydimethyltryptamines; Rats; Regional Blood Flow; Serotonin; Skin; Substance P; Tachyphylaxis; Vasodilation	1991
Nor-binaltorphimine decreases deprivation and opioid-induced feeding. Brain research, 1990, Nov-26, Volume: 534, Issue:1-2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Feeding Behavior; Food Deprivation; Male; Naltrexone; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Reference Values	1990
Activation of mu- and delta-opioid receptors present on the same nerve terminals depresses transmitter release in the mouse hypogastric ganglion. British journal of pharmacology, 1990, Volume: 101, Issue:3 Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Evoked Potentials; Ganglia; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; Nerve Endings; Neurotransmitter Agents; Oligopeptides; Potassium Channels; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1990
Modulation of mu, delta and kappa opioid receptors in rat brain by metal ions and histidine. Neuropharmacology, 1990, Volume: 29, Issue:5 Topics: Animals; Brain Chemistry; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Histidine; Kinetics; Male; Membranes; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfhydryl Reagents; Trace Elements; Zinc	1990
Role of peripheral mu, delta and kappa opioid receptors in opioid-induced inhibition of gastrointestinal transit in rats. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1 Topics: Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Gastrointestinal Motility; Male; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1990
Involvement of multiple opiate receptors in opioid kindling. Brain research, 1990, May-28, Volume: 517, Issue:1-2 Topics: Animals; beta-Endorphin; Convulsants; Endorphins; Enkephalin, Leucine; Kindling, Neurologic; Male; Morphine; Oligopeptides; Rats; Receptors, Opioid	1990
[Kinetic characteristics of the effect of GTP on properties of opioid receptors]. Biokhimiia (Moscow, Russia), 1990, Volume: 55, Issue:6 Topics: Adenine Nucleotides; Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Kinetics; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1990
Differential effects of cyanogen bromide on ligand binding by mu, delta and kappa opioid receptors. Life sciences, 1990, Volume: 47, Issue:24 Topics: Animals; Brain; Cell Membrane; Cyanogen Bromide; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Ligands; Male; Methionine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1990
Effects of iontophoretically applied alpha-casein exorphin on CA1 hippocampal field potentials in vivo. Progress in clinical and biological research, 1990, Volume: 328 Topics: Amino Acid Sequence; Animals; Caseins; Electric Stimulation; Enkephalin, Leucine; Evoked Potentials; Hippocampus; Iontophoresis; Molecular Sequence Data; Morphine; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains	1990
Opposite dopaminergic activity in lateral and median hypothalamic nuclei in relation to the feeding effect of D-Ser2-Leu-Enk-Thr6 (DSLET). Brain research, 1990, Feb-26, Volume: 510, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Enkephalin, Leucine; Feeding Behavior; Female; Hypothalamic Area, Lateral; Hypothalamus, Middle; Oligopeptides; Rats; Rats, Inbred Strains	1990
Relationship between opioid-receptor occupancy and stimulation of low-Km GTPase in brain membranes. Journal of neurochemistry, 1989, Volume: 52, Issue:4 Topics: Animals; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP Phosphohydrolases; Guanosine Triphosphate; Magnesium; Membranes; Naltrexone; Oligopeptides; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium	1989
Selective inhibitory effects of ethylketocyclazocine on reflex pathways to the external urethral sphincter of the cat. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: Animals; Cats; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Female; Morphine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, kappa; Reflex; Urethra; Urinary Bladder; Urinary Incontinence	1989
Paradoxical analgesia produced by low doses of the opiate-antagonist naloxone is mediated by interaction at a site with characteristics of the delta opioid receptor. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:1 Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Male; Morphine; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta	1989
Differential down-regulation of delta opioid binding sites during physical dependence on methionine enkephalin in the rat. Life sciences, 1989, Volume: 44, Issue:20 Topics: Animals; Brain; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Substance-Related Disorders	1989
Effects of streptozotocin-induced diabetes on feeding stimulated by centrally administered opioid agonists. Life sciences, 1989, Volume: 45, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analysis of Variance; Animals; Diabetes Mellitus, Experimental; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Male; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid	1989
Guanine nucleotide regulation of [125I]beta-endorphin binding to NG108-15 and SK-N-SH cell membranes: specific cation requirements. Brain research, 1989, Jul-24, Volume: 493, Issue:1 Topics: beta-Endorphin; Cations; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Glioma; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Hybrid Cells; Neuroblastoma; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride; Tumor Cells, Cultured	1989
Changes in multiple opioid receptors in regions of the brain in rats treated chronically with thyroxine. Neuropharmacology, 1989, Volume: 28, Issue:9 Topics: Animals; Blood Pressure; Body Weight; Brain; Chromatography, High Pressure Liquid; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Heart Rate; Hyperthyroidism; Male; Membranes; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Thyroxine	1989
Delta opioid receptor selectivity induced by conformational constraints in linear enkephalin-related peptides: 1H 400-MHz NMR study and theoretical calculations. Biochemistry, 1989, Sep-05, Volume: 28, Issue:18 Topics: Amino Acid Sequence; Chemical Phenomena; Chemistry; Dimethyl Sulfoxide; Enkephalin, Leucine; Enkephalins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Protein Binding; Protein Conformation; Receptors, Opioid; Temperature	1989
Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice. European journal of pharmacology, 1989, Sep-22, Volume: 168, Issue:3 Topics: Analgesia; Anesthesia, Spinal; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1989
Dermorphin gene sequence peptide with high affinity and selectivity for delta-opioid receptors. The Journal of biological chemistry, 1989, Feb-25, Volume: 264, Issue:6 Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Oligopeptides; Opioid Peptides; Protein Conformation; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Synaptosomes	1989
A quantitative study of [3H]D-Ala2-D-Leu5-enkephalin binding to rat brain membranes. Evidence that oxymorphone is a noncompetitive inhibitor of the lower affinity delta-binding site. Molecular pharmacology, 1985, Volume: 27, Issue:3 Topics: Animals; Autoradiography; Brain; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Hydromorphone; Male; Manganese; Manganese Compounds; Mathematics; Membranes; Oligopeptides; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride	1985
Selective effects of ethanol on opiate receptor subtypes in brain. Neuropharmacology, 1987, Volume: 26, Issue:10 Topics: Animals; Benzomorphans; Binding, Competitive; Brain Chemistry; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethanol; In Vitro Techniques; Limbic System; Male; Mice; Mice, Inbred C57BL; Narcotics; Oligopeptides; Receptors, Opioid	1987
Opioid receptors inhibit the adenylate cyclase in guinea pig cochleas. Brain research, 1987, Sep-22, Volume: 421, Issue:1-2 Topics: Adenylyl Cyclases; Animals; Cochlea; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; In Vitro Techniques; Morphine; Naloxone; Oligopeptides; Receptors, Opioid	1987
Autoradiographic distribution of multiple classes of opioid receptor binding sites in human forebrain. Brain research bulletin, 1987, Volume: 19, Issue:5 Topics: Aged; Autoradiography; Benzomorphans; Binding Sites; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Female; Humans; Male; Middle Aged; Oligopeptides; Receptors, Opioid; Tissue Distribution	1987
Opiate-inhibited adenylate cyclase in rat brain membranes depleted of Gs-stimulated adenylate cyclase. Journal of neurochemistry, 1988, Volume: 50, Issue:2 Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Brain; Cell Membrane; Cholera Toxin; Colforsin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Male; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Fluoride; Virulence Factors, Bordetella	1988
Investigation of the structural parameters involved in the mu and delta opioid receptor discrimination of linear enkephalin-related peptides. Journal of medicinal chemistry, 1988, Volume: 31, Issue:2 Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Mice; Muscle Contraction; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship	1988
Spare ligand binding sites in the coupling of opioid receptor to brain GTPase. NIDA research monograph, 1986, Volume: 75 Topics: Alkylation; Animals; Brain; Cell Membrane; Enkephalin, Leucine; GTP Phosphohydrolases; Kinetics; Ligands; Oligopeptides; Phosphoric Monoester Hydrolases; Rats; Receptors, Opioid; Receptors, Opioid, delta	1986
Molecular mechanisms of ligand binding to opioid receptors: selective inhibition by ethanol? NIDA research monograph, 1986, Volume: 75 Topics: Animals; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethanol; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spectrophotometry, Infrared	1986
The direct demonstration of binding of mu, delta and kappa agonists to digitonin-solubilized opioid receptors from bovine striatum. NIDA research monograph, 1986, Volume: 75 Topics: Analgesics; Animals; Benzomorphans; Cattle; Cell Membrane; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Morphinans; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1986
New approaches to the evaluation of opioid agonists and antagonists upon the isolated, electrically stimulated mouse vas deferens preparation. NIDA research monograph, 1987, Volume: 76 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Receptors, Opioid; Vas Deferens	1987
Multiple agonist-affinity states of opioid receptors: regulation of binding by guanyl nucleotides in guinea pig cortical, NG108-15, and 7315c cell membranes. Molecular pharmacology, 1988, Volume: 33, Issue:4 Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanine Nucleotides; Guinea Pigs; Kinetics; Male; Naloxone; Oligopeptides; Pertussis Toxin; Receptors, Opioid; Virulence Factors, Bordetella	1988
Effect of ethanol on the binding of conformationally rigid and labile ligands of opioid receptors to rat brain membranes. Biochemical pharmacology, 1988, Jun-01, Volume: 37, Issue:11 Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethanol; In Vitro Techniques; Male; Naltrexone; Oligopeptides; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Opioid	1988
ADP-ribosylation with pertussis toxin modulates the GTP-sensitive opioid ligand binding in digitonin-soluble extracts of rat brain membranes. Journal of neurochemistry, 1988, Volume: 51, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cell Membrane; Digitonin; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Receptors, Opioid; Sodium; Solubility; Virulence Factors, Bordetella	1988
Role of mu 1-opiate receptors in supraspinal opiate analgesia: a microinjection study. Brain research, 1988, Apr-26, Volume: 447, Issue:1 Topics: Analgesia; Animals; Brain; Cerebral Ventricles; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Male; Microinjections; Morphine; Oligopeptides; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Spinal Cord	1988
Evidence that endogenous enkephalins and a delta opioid receptor agonist have a common site of action in spinal antinociception. European journal of pharmacology, 1988, Apr-13, Volume: 148, Issue:3 Topics: Analgesia; Animals; Dipeptides; Enkephalin, Leucine; Enkephalins; Oligopeptides; Rats; Receptors, Opioid; Spinal Cord	1988
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naltrexone; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa	1988
Effect of methimazole-induced hypothyroidism on multiple opioid receptors in rat brain regions. Pharmacology, 1988, Volume: 37, Issue:6 Topics: Animals; Body Temperature; Body Weight; Brain Chemistry; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Heart Rate; Hypothyroidism; Male; Methimazole; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Triiodothyronine	1988
The stimulation of food intake by selective agonists of mu, kappa and delta opioid receptors. Life sciences, 1986, Mar-24, Volume: 38, Issue:12 Topics: Animals; Dose-Response Relationship, Drug; Drinking; Dynorphins; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid	1986
Comparison of the antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal gray matter, medial and paramedial ventral medulla in the rat as studied by the microinjection technique. Brain research, 1986, May-07, Volume: 372, Issue:2 Topics: Analgesics, Opioid; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Medulla Oblongata; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sufentanil	1986
Effects of beta-chlornaltrexamine on food intake, body weight and opioid-induced feeding. Life sciences, 1987, Apr-13, Volume: 40, Issue:15 Topics: Animals; Body Weight; Dynorphins; Eating; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Male; Naltrexone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid	1987
Opioid receptor-mediated responses in the dentate gyrus and CA1 region of the rat hippocampus. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GABA Antagonists; Hippocampus; Interneurons; Naloxone; Oligopeptides; Rats; Receptors, Opioid	1988
Opiate binding in calf thalamic membranes: a selective mu 1 binding assay. Molecular pharmacology, 1988, Volume: 34, Issue:3 Topics: Animals; Cattle; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thalamus	1988
Regulation of human natural cytotoxicity by enkephalins and selective opiate agonists. Brain, behavior, and immunity, 1988, Volume: 2, Issue:3 Topics: Adult; Cell Division; Cytotoxicity, Immunologic; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Humans; Killer Cells, Natural; Lymphocytes; Naloxone; Oligopeptides; Receptors, Opioid; T-Lymphocytes	1988
Evidence that the delta-selective alkylating agent, fit, alters the mu-noncompetitive opiate delta binding site. Neuropeptides, 1985, Volume: 6, Issue:3 Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; In Vitro Techniques; Isothiocyanates; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta	1985
Interaction of opiates with opioid binding sites in the bovine adrenal medulla: I. Interaction with delta and mu sites. Journal of neurochemistry, 1985, Volume: 45, Issue:3 Topics: Adrenal Medulla; Animals; Binding Sites; Cattle; Cesium; Chlorides; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylmaleimide; Kinetics; Lithium; Narcotics; Oligopeptides; Phospholipases A; Potassium; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium; Stereoisomerism	1985
Interaction of opiates with opioid binding sites in the bovine adrenal medulla: II. Interaction with kappa sites. Journal of neurochemistry, 1985, Volume: 45, Issue:3 Topics: Adrenal Medulla; Animals; Benzomorphans; Binding Sites; Calcium; Cattle; Cyclazocine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethylketocyclazocine; Ethylmaleimide; Etorphine; Guinea Pigs; Kinetics; Lithium; Manganese; Narcotics; Oligopeptides; Phospholipases A; Potassium; Receptors, Opioid; Receptors, Opioid, kappa; Sodium; Stereoisomerism	1985
Sulfonic acid enkephalin: binding specificity to rat brain opiate receptors. Neuropeptides, 1985, Volume: 6, Issue:4 Topics: Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Kinetics; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid	1985
Receptors for opioid peptides in the guinea-pig ileum. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2 Topics: Alkylation; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens	1985
Selective cardiovascular and neuroendocrine effects of a kappa-opioid agonist in the nucleus tractus solitarii of rats. The Journal of physiology, 1985, Volume: 367 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Arginine Vasopressin; Benzomorphans; Enkephalin, Leucine; Hemodynamics; Male; Medulla Oblongata; Oligopeptides; Phenoxybenzamine; Pyrrolidines; Rats; Rats, Brattleboro; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Time Factors	1985
Synthesis and activity profiles of novel cyclic opioid peptide monomers and dimers. Journal of medicinal chemistry, 1985, Volume: 28, Issue:12 Topics: Amino Acid Sequence; Animals; Biological Assay; Brain; Chemical Phenomena; Chemistry; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Ileum; Macromolecular Substances; Male; Mice; Muscle Contraction; Oligopeptides; Peptides, Cyclic; Protein Conformation; Rats; Receptors, Opioid; Structure-Activity Relationship; Vas Deferens	1985
Regional cerebral blood flow during enkephalin-induced seizures in the rat. Neuropharmacology, 1986, Volume: 25, Issue:4 Topics: Animals; Blood Pressure; Brain; Cerebellum; Enkephalin, Leucine; Epilepsy; Heart Rate; Injections, Intraventricular; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta	1986
Opiate-induced seizures: a study of mu and delta specific mechanisms. Experimental neurology, 1986, Volume: 93, Issue:2 Topics: Animals; Electroencephalography; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Narcotics; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures	1986
Sodium regulation of agonist binding at opioid receptors. II. Effects of sodium replacement on opioid binding in guinea pig cortical membranes. Molecular pharmacology, 1986, Volume: 30, Issue:2 Topics: Animals; Cell Membrane; Cerebral Cortex; Cyclazocine; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Guinea Pigs; Male; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium	1986
Probes for narcotic receptor mediated phenomena. 13. Potential irreversible narcotic antagonist-based ligands derived from 6,14-endo-ethenotetrahydronororipavine with 7-(methoxyfumaroyl)amino, (bromoacetyl)amino, or isothiocyanate electrophiles: chemistry Journal of medicinal chemistry, 1986, Volume: 29, Issue:11 Topics: Animals; Brain; Enkephalin, Leucine; Fentanyl; In Vitro Techniques; Isothiocyanates; Ligands; Male; Mice; Mice, Inbred ICR; Narcotic Antagonists; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Thebaine; Thiocyanates	1986
[D-Pen2,D-Pen5]enkephalin (DPDPE): a delta-selective enkephalin with low affinity for mu 1 opiate binding sites. European journal of pharmacology, 1986, Sep-09, Volume: 128, Issue:3 Topics: Animals; Brain Chemistry; Cattle; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1986
Selective proliferation of brain kappa opiate receptors in spontaneously hypertensive rats. Life sciences, 1986, Dec-29, Volume: 39, Issue:26 Topics: Animals; Binding, Competitive; Brain; Cyclazocine; Enkephalin, Leucine; Ethylketocyclazocine; Kinetics; Male; Naltrexone; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Opioid; Receptors, Opioid, kappa	1986
Interaction of [D-Ser2,Leu5]enkephalin-Thr6 (DSLET), a relatively selective delta ligand, with mu1 opioid binding sites. Life sciences, 1987, Jan-19, Volume: 40, Issue:3 Topics: Animals; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Male; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid	1987
Pharmacological and anatomical evidence of selective mu, delta, and kappa opioid receptor binding in rat brain. Brain research, 1986, Dec-03, Volume: 399, Issue:1 Topics: Animals; Autoradiography; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1986
Unidirectional interaction between thyrotropin releasing hormone and opiates at the level of their brain receptors. General pharmacology, 1987, Volume: 18, Issue:1 Topics: Animals; Brain; Cyclazocine; Enkephalin, Leucine; Ethylketocyclazocine; Male; Naltrexone; Oligopeptides; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Thyrotropin-Releasing Hormone	1987
Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: Analgesia; Anesthesia, Spinal; Animals; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Morphine; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1987
Differential maturation of mu and delta opioid receptors in the chick embryonic brain. Neurochemical research, 1987, Volume: 12, Issue:3 Topics: Animals; Brain; Chick Embryo; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Levorphanol; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1987
Effects of delta opioid antagonists on enkephalin-induced seizures. Pharmacology, 1987, Volume: 34, Issue:2-3 Topics: Animals; Enkephalin, Leucine; Male; Narcotic Antagonists; Oligopeptides; Rats; Receptors, Opioid; Seizures	1987
DSLET (D-ser2-leu5-enkephalin-Thr6) produces analgesia on the hot plate by mechanisms largely different from DAGO and morphine-like opioids. Life sciences, 1987, Jul-27, Volume: 41, Issue:4 Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Mice; Mice, Inbred Strains; Oligopeptides; Species Specificity; Structure-Activity Relationship	1987
Effect of beta-FNA on opiate delta receptor binding. Journal of neurochemistry, 1984, Volume: 43, Issue:4 Topics: Animals; Brain; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Naloxone; Naltrexone; Oligopeptides; Protein Conformation; Rats; Receptors, Opioid	1984
Pharmacological identification of delta and mu opiate receptors on bulbar respiratory neurons. European journal of pharmacology, 1984, Feb-17, Volume: 98, Issue:2 Topics: Animals; Cats; Enkephalin, Leucine; Glutamates; Glutamic Acid; Medulla Oblongata; Naloxone; Neurons; Oligopeptides; Receptors, Opioid; Respiratory Center; Respiratory Function Tests	1984
[3H]Tyr-D-Ser-Gly-Phe-Leu-Thr: a specific probe for the delta-opiate receptor subtype in brain membranes. European journal of pharmacology, 1982, Mar-12, Volume: 78, Issue:3 Topics: Animals; Brain; Enkephalin, Leucine; In Vitro Techniques; Kinetics; Membranes; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid	1982
Interaction of naloxone with mu- and delta-opioid agonists on the respiration of rats. European journal of pharmacology, 1983, Feb-18, Volume: 87, Issue:2-3 Topics: Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Depression, Chemical; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Injections, Intraventricular; Male; Morphine; Naloxone; Narcotics; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration; Time Factors	1983
Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors. Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:19 Topics: Animals; Binding, Competitive; Biological Assay; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Isomerism; Kinetics; Muscle Contraction; Naloxone; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship	1983
Different effects of mu and delta opiate agonists on respiration. European journal of pharmacology, 1984, Feb-17, Volume: 98, Issue:2 Topics: Animals; Enkephalin, Leucine; Male; Oligopeptides; Peptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Respiration; Respiratory Function Tests; Tidal Volume	1984
Metabolic rate in different rat brain areas during seizures induced by a specific delta opiate receptor agonist. Brain research, 1984, Jun-04, Volume: 302, Issue:1 Topics: Animals; Brain; Carbon Radioisotopes; Deoxy Sugars; Deoxyglucose; Electroencephalography; Enkephalin, Leucine; Kinetics; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures	1984
A comparative study in rats of the respiratory depression and analgesia induced by mu- and delta-opioid agonists. European journal of pharmacology, 1984, Mar-16, Volume: 99, Issue:1 Topics: Analgesia; Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Male; Morphine; Oligopeptides; Rats; Rats, Inbred Strains; Respiration	1984
The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat. Brain research, 1984, Apr-23, Volume: 298, Issue:1 Topics: Animals; Cats; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Morphine; Naloxone; Oligopeptides; Reflex; Thiorphan; Tiopronin; Urination	1984
Differential epileptogenic potentials of selective mu and delta opiate receptor agonists. Journal of neural transmission, 1983, Volume: 57, Issue:1-2 Topics: Animals; Convulsants; Drug Interactions; Endorphins; Enkephalin, Leucine; Hippocampus; Injections; Injections, Intraventricular; Male; Oligopeptides; Rats; Rats, Inbred Strains; Seizures	1983
Protein kinase C involvement in homologous desensitization of delta-opioid receptor coupled to Gi1-phospholipase C activation in Xenopus oocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:11 Topics: Animals; Electrophysiology; Enkephalin, Leucine; Enzyme Activation; GTP-Binding Proteins; Injections; Oocytes; Protein Kinase C; Receptors, Muscarinic; Receptors, Opioid, delta; RNA; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Xenopus laevis	1995
Anti-idiotypic antibodies: a useful alternative for studying the biochemical expression of mu/delta opioid binding sites in mammalian brain. Journal of neuroimmunology, 1995, Volume: 62, Issue:2 Topics: Animals; Antibodies, Anti-Idiotypic; Binding Sites; Brain Chemistry; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Immunoblotting; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured	1995
Different responses to opioids measured in terminals and somas of Edinger-Westphal neurons. Neuroscience, 1993, Volume: 57, Issue:2 Topics: Amino Acid Sequence; Animals; Chickens; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Ganglia, Parasympathetic; GTP-Binding Proteins; In Vitro Techniques; Molecular Sequence Data; Naloxone; Nerve Endings; Neurons; Receptors, Opioid, delta; Receptors, Opioid, mu; Reticular Formation; Substance P	1993
Species and age-dependent differences of functional coupling between opioid delta-receptor and G-proteins and possible involvement of protein kinase C in striatal membranes. Neuroscience letters, 1994, Jul-18, Volume: 176, Issue:1 Topics: Aging; Analgesics; Animals; Carbazoles; Cell Membrane; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Guinea Pigs; Indoles; Kinetics; Male; Naltrexone; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Species Specificity	1994
Opioid-induced increase in [Ca2+]i in ND8-47 neuroblastoma x dorsal root ganglion hybrid cells is mediated through G protein-coupled delta-opioid receptors and desensitized by chronic exposure to opioid. Journal of neurochemistry, 1995, Volume: 65, Issue:4 Topics: Calcium; Calcium Channels; Cholera Toxin; Dihydropyridines; Enkephalin, Leucine; Ganglia, Spinal; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hybrid Cells; Intracellular Membranes; Narcotics; Neuroblastoma; Osmolar Concentration; Pertussis Toxin; Receptors, Opioid; Receptors, Opioid, delta; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella	1995
Distribution of the mu and delta opioid binding sites in the brain of the alcohol-preferring AA and alcohol-avoiding ANA lines of rats. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1 Topics: Alcoholism; Analgesics; Animals; Autoradiography; Binding Sites; Brain; Cerebellum; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Enkephalin, Leucine; Kinetics; Male; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu	1995
VV-hemorphin-7 and LVV-hemorphin-7 released during in vitro peptic hemoglobin hydrolysis are morphinomimetic peptides. Neuropeptides, 1995, Volume: 28, Issue:4 Topics: Animals; Binding, Competitive; Cattle; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Hemoglobins; Hydrolysis; Ileum; Male; Morphine; Naloxone; Pepsin A; Peptide Fragments; Rats; Rats, Wistar; Receptors, Opioid; Sensitivity and Specificity	1995
Opioids modify the release of LH at the pituitary level: in vitro studies with entire rat pituitaries. The Journal of endocrinology, 1995, Volume: 145, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzomorphans; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Naloxone; Narcotics; Oligopeptides; Organ Culture Techniques; Pituitary Gland; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1995
Antisense oligodeoxynucleotide to the Gi2 protein alpha subunit sequence inhibits an opioid-induced increase in the intracellular free calcium concentration in ND8-47 neuroblastoma x dorsal root ganglion hybrid cells. Molecular pharmacology, 1995, Volume: 48, Issue:2 Topics: Analgesics; Base Sequence; Calcium; Calcium Channels; Cells, Cultured; Enkephalin, Leucine; Ganglia, Spinal; GTP-Binding Proteins; Hybrid Cells; Molecular Sequence Data; Neuroblastoma; Oligonucleotides, Antisense; Receptors, Opioid, delta	1995
The modulation of placental lactogen release by opioids: a role for extracellular calcium. Molecular and cellular endocrinology, 1993, Volume: 90, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Analgesics; Calcium; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Gene Expression Regulation; Humans; Ionomycin; Naloxone; Naltrexone; Narcotics; Pertussis Toxin; Placental Lactogen; Pyrrolidines; Time Factors; Trophoblasts; Virulence Factors, Bordetella	1993
Evidence for functional delta-opiate receptors in the rat intestine. The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:10 Topics: Acetylcholine; Animals; Cricetinae; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; In Vitro Techniques; Jejunum; Male; Mice; Muscle Contraction; Muscle, Smooth; Naltrexone; Rats; Rats, Wistar; Receptors, Opioid, delta	1994
Acute tolerance to the excitatory effects of opioids in the rat hippocampus. Journal of neuroscience research, 1995, Jan-01, Volume: 40, Issue:1 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Evoked Potentials; Hippocampus; Male; Narcotics; Pyramidal Cells; Rats; Rats, Wistar	1995
[Participation of central opiate receptors in the pathogenesis of adrenal arrhythmias]. Biulleten' eksperimental'noi biologii i meditsiny, 1994, Volume: 118, Issue:9 Topics: Adrenal Gland Diseases; Animals; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Rats; Rats, Wistar; Receptors, Opioid	1994
Protein kinase inhibitor potentiates opioid delta-receptor currents in Xenopus oocytes. Neuroreport, 1994, Oct-03, Volume: 5, Issue:15 Topics: Analgesics; Animals; Carbazoles; Chloride Channels; Enkephalin, Leucine; GTP-Binding Proteins; Indole Alkaloids; Mice; Oocytes; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Receptors, Opioid, delta; RNA, Messenger; Signal Transduction; Xenopus laevis	1994
Opiate withdrawal intensity correlates with the presence of DSLET high-affinity binding. Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:4 Topics: Amino Acid Sequence; Analgesics; Animals; Drug Implants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Sequence Data; Morphine; Morphine Dependence; Naloxone; Narcotics; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance Withdrawal Syndrome	1994
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin	1993
[3H]dynorphin1-8 binding sites in frog (Rana esculenta) brain membranes. Neuropeptides, 1994, Volume: 26, Issue:5 Topics: Amino Acid Sequence; Animals; Brain; Cell Membrane; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Naloxone; Peptide Fragments; Rana esculenta; Receptors, Opioid; Sodium Chloride; Tritium	1994
The effect of naltrindole on spinal and supraspinal delta opioid receptors and analgesia. Life sciences, 1994, Volume: 55, Issue:19 Topics: Analgesia; Analgesics; Animals; Brain; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Injections, Spinal; Kinetics; Male; Mice; Naltrexone; Pain Measurement; Receptors, Opioid, delta; Spinal Cord	1994
Analysis of delta-opioid receptor activities stably expressed in CHO cell lines: function of receptor density? The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3 Topics: Adenylyl Cyclase Inhibitors; Animals; Base Sequence; CHO Cells; Cricetinae; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Molecular Sequence Data; Receptors, Opioid, delta; RNA, Messenger; Transfection	1994
Evidence that weaning stimulates the developmental expression of a delta-opioid receptor subtype in the rat. Brain research. Developmental brain research, 1994, Mar-18, Volume: 78, Issue:1 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine; Female; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Weaning	1994
Agonists and antagonists bind to different domains of the cloned kappa opioid receptor. Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-16, Volume: 91, Issue:17 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Base Sequence; Benzeneacetamides; Binding Sites; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Colforsin; Cyclic AMP; Enkephalin, Leucine; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Naltrexone; Oligodeoxyribonucleotides; Protein Structure, Secondary; Pyrrolidines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Recombinant Fusion Proteins; Recombinant Proteins; Transfection	1994
Opioid receptor density changes in Alzheimer amygdala and putamen. Brain research, 1993, Dec-31, Volume: 632, Issue:1-2 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amygdala; Analgesics; Autoradiography; Benzeneacetamides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Female; Frontal Lobe; Humans; Kinetics; Male; Putamen; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reference Values; Tritium	1993
[The participation of the delta opioid receptors in immunomodulation]. Fiziologicheskii zhurnal imeni I.M. Sechenova, 1993, Volume: 79, Issue:12 Topics: Animals; Cyproheptadine; Enkephalin, Leucine; Haloperidol; Immunization; Male; Mice; Mice, Inbred CBA; Narcotic Antagonists; Neuroimmunomodulation; Pituitary Gland; Receptors, Opioid, delta; Thymus Gland	1993
Purification to homogeneity of an active opioid receptor from rat brain by affinity chromatography. Proceedings of the National Academy of Sciences of the United States of America, 1994, May-10, Volume: 91, Issue:10 Topics: Analgesics; Animals; Antibodies; Binding, Competitive; Blotting, Western; Brain; Cell Membrane; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Male; Molecular Weight; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Ultrafiltration	1994
Delta opioid receptor mediates phospholipase C activation via Gi in Xenopus oocytes. FEBS letters, 1993, Nov-01, Volume: 333, Issue:3 Topics: Analgesics; Animals; Benzeneacetamides; Electric Conductivity; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Enzyme Activation; Female; Gene Expression; GTP-Binding Proteins; Membrane Potentials; Mice; Naltrexone; Narcotic Antagonists; Oocytes; Pyrrolidines; Receptors, Opioid, delta; Type C Phospholipases; Xenopus laevis	1993
Modification of G protein-coupled functions by low-pH pretreatment of membranes from NG108-15 cells: increase in opioid agonist efficacy by decreased inactivation of G proteins. Molecular pharmacology, 1993, Volume: 44, Issue:4 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Animals; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Rats; Receptors, Opioid; Sodium; Tritium; Tumor Cells, Cultured	1993
Convulsive effects of systemic administration of the delta opioid agonist BW373U86 in mice. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2 Topics: Amino Acid Sequence; Animals; Anticonvulsants; Benzamides; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Midazolam; Molecular Sequence Data; Naltrexone; Pentylenetetrazole; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures	1993
Differential antagonism by naltrindole-5'-isothiocyanate on [3H]DSLET and [3H]DPDPE binding to striatal slices of mice. Life sciences, 1993, Volume: 53, Issue:23 Topics: Analgesics; Animals; Corpus Striatum; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; In Vitro Techniques; Isothiocyanates; Kinetics; Male; Mice; Naltrexone; Radioligand Assay; Receptors, Opioid, delta; Tritium	1993
Evidence for delta opioid receptor subtypes regulating adenylyl cyclase activity in rat brain. Life sciences, 1994, Volume: 54, Issue:7 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Animals; Benzylidene Compounds; Caudate Nucleus; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta	1994
Electrophysiological actions of delta opioids in CA1 of the rat hippocampal slice are mediated by one delta receptor subtype. Brain research, 1993, Jan-22, Volume: 601, Issue:1-2 Topics: Analgesics; Animals; Electric Stimulation; Electrophysiology; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Evoked Potentials; Hippocampus; In Vitro Techniques; Indoles; Ligands; Male; Morphinans; Morphine; Naltrexone; Narcotic Antagonists; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu	1993
Involvement of delta 2 opioid receptors in the development of morphine dependence in mice. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3 Topics: Animals; Enkephalin, Leucine; Isothiocyanates; Male; Mice; Morphinans; Morphine Dependence; Naloxone; Naltrexone; Receptors, Opioid, delta; Substance Withdrawal Syndrome; Thiocyanates	1993
Agonist and antagonist profiles of [D-Ala2,Glu4]deltorphin and its [Cys4]- and [Ser4]-substituted derivatives: further evidence of opioid delta receptor multiplicity. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2 Topics: Amino Acid Sequence; Analgesics; Animals; Brain Chemistry; Cysteine; Enkephalin, Leucine; Male; Mice; Molecular Sequence Data; Oligopeptides; Rats; Receptors, Opioid, delta; Serine	1993
Involvement of delta 2 opioid receptors in acute dependence on morphine in mice. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3 Topics: Animals; Drug Interactions; Enkephalin, Leucine; Isothiocyanates; Male; Mice; Morphine; Naltrexone; Receptors, Opioid, delta; Substance-Related Disorders; Thiocyanates	1993
Alterations in delta opioid receptor levels in discrete areas of the neocortex and in the globus pallidus of the aging guinea pig: a quantitative autoradiographic study. Brain research, 1993, Jun-18, Volume: 614, Issue:1-2 Topics: Aging; Analgesics; Animals; Autoradiography; Cerebral Cortex; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Globus Pallidus; Guinea Pigs; In Vitro Techniques; Male; Radioligand Assay; Receptors, Opioid, delta	1993
The peristaltic reflex in the rat ileum: evidence for functional mu- and delta-opiate receptors. The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:8 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Antidiarrheals; Diphenoxylate; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ileum; Linear Models; Loperamide; Morphine; Peristalsis; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu	1995
Studies on mu and delta opioid receptor selectivity utilizing chimeric and site-mutagenized receptors. Proceedings of the National Academy of Sciences of the United States of America, 1995, Dec-19, Volume: 92, Issue:26 Topics: Amino Acid Sequence; Analgesics; Base Sequence; Benzomorphans; Binding, Competitive; Cell Line; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Etorphine; GTP-Binding Proteins; Humans; Kidney; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Protein Structure, Secondary; Receptors, Opioid, delta; Receptors, Opioid, mu; Recombinant Fusion Proteins; Substrate Specificity; Transfection	1995
Studies on inhibition of mu and delta opioid receptor binding by dithiothreitol and N-ethylmaleimide. His223 is critical for mu opioid receptor binding and inactivation by N-ethylmaleimide. The Journal of biological chemistry, 1996, Mar-08, Volume: 271, Issue:10 Topics: Amino Acid Sequence; Analgesics; Base Sequence; Binding Sites; Cell Line; Cell Membrane; Dithiothreitol; DNA Primers; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylmaleimide; Histidine; Humans; Kidney; Kinetics; Ligands; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Receptors, Opioid, delta; Receptors, Opioid, mu; Recombinant Fusion Proteins; Serine; Transfection	1996
Characterization of supraspinal antinociceptive actions of opioid delta agonists in the rat. Pain, 1995, Volume: 62, Issue:3 Topics: Animals; Cerebral Ventricles; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hot Temperature; Injections, Intraventricular; Male; Medulla Oblongata; Morphine; Nociceptors; Oligopeptides; Pain Measurement; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reticular Formation	1995
The effects of delta-opioid receptor agonists on synaptic transmission in hamster submandibular ganglion. The Bulletin of Tokyo Dental College, 1995, Volume: 36, Issue:2 Topics: Animals; Autonomic Fibers, Preganglionic; Cricetinae; Dimethylphenylpiperazinium Iodide; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Ganglia, Parasympathetic; Ganglionic Stimulants; Naloxone; Narcotic Antagonists; Presynaptic Terminals; Receptors, Opioid, delta; Submandibular Gland; Synaptic Transmission	1995
Involvement of delta-opioid receptors in immunosuppression. The International journal of neuroscience, 1996, Volume: 84, Issue:1-4 Topics: Analgesics; Animals; Dopamine Agents; Enkephalin, Leucine; Hypothalamus; Immunoglobulin M; Immunosuppressive Agents; Male; Mice; Mice, Inbred CBA; Pituitary Gland; Receptors, Opioid, delta; Receptors, Serotonin; Rosette Formation; Serotonin Agents; Thymus Gland; Viral Plaque Assay	1996
[Mediated participation of the opioid system in regulation of pain sensitivity by peptide fragments MP1 and MP2]. Biokhimiia (Moscow, Russia), 1996, Volume: 61, Issue:3 Topics: Amino Acid Sequence; Analgesics; Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Molecular Sequence Data; Oligopeptides; Pain Threshold; Peptides; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu	1996
Opioid regulation of intracellular free calcium in cultured mouse dorsal root ganglion neurons. Journal of neuroscience research, 1996, May-15, Volume: 44, Issue:4 Topics: Analgesics; Animals; Benzeneacetamides; Calcium; Cells, Cultured; Embryo, Mammalian; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ganglia, Spinal; Kinetics; Mice; Mice, Inbred C57BL; Neurons; Potassium Chloride; Pyrrolidines; Substance P	1996
Supraspinal delta 2 opioid agonist analgesia in Swiss-Webster mice involves spinal GABAA receptors. Pharmacology, biochemistry, and behavior, 1996, Volume: 54, Issue:2 Topics: Amino Acid Sequence; Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; GABA Antagonists; GABA-A Receptor Antagonists; Heroin; Injections, Intraventricular; Injections, Spinal; Mice; Molecular Sequence Data; Morphine Derivatives; Pain Measurement; Receptors, GABA-A; Receptors, Opioid, delta; Spinal Cord	1996
Protein kinase C inhibitor potentiates the agonist-induced GTPase activity in COS cell membranes expressing delta-opioid receptor. Brain research. Molecular brain research, 1995, Volume: 33, Issue:2 Topics: Analgesics; Animals; Cell Line; Cell Membrane; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Leucine; Enzyme Inhibitors; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kidney; Kinetics; Naphthalenes; Protein Kinase C; Receptors, Opioid, delta; Recombinant Proteins; Transfection	1995
Autoradiographic comparison of [3H]DPDPE and [3H]DSLET binding: evidence for distinct delta 1 and delta 2 opioid receptor populations in rat brain. Brain research, 1996, May-06, Volume: 719, Issue:1-2 Topics: Animals; Autoradiography; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta	1996
The antiproliferative effect of opioid receptor agonists on the T47D human breast cancer cell line, is partially mediated through opioid receptors. European journal of pharmacology, 1996, Jan-25, Volume: 296, Issue:2 Topics: Adenocarcinoma; Amino Acid Sequence; Binding Sites; Breast Neoplasms; Cell Division; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Humans; Molecular Sequence Data; Morphine; Narcotic Antagonists; Opioid Peptides; Receptors, Opioid; Tumor Cells, Cultured	1996
Role of protein kinase C in desensitization of spinal delta-opioid-mediated antinociception in the mouse. British journal of pharmacology, 1996, Volume: 118, Issue:7 Topics: Analgesics; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Leucine; Enzyme Inhibitors; Indoles; Injections, Spinal; Male; Membranes; Mice; Mice, Inbred ICR; Naphthalenes; Oligopeptides; Pain Measurement; Protein Kinase C; Pyrroles; Receptors, Opioid; Receptors, Opioid, delta; Spinal Cord	1996
Mu and delta opioid receptor gene expression after chronic treatment with opioid agonist. Neuroreport, 1996, Jun-17, Volume: 7, Issue:9 Topics: Animals; Brain; Cell Line; Enkephalin, Leucine; Gene Expression Regulation; Genetic Code; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; RNA, Messenger	1996
Identification of the critical domains of the delta-opioid receptor involved in G protein coupling using site-specific synthetic peptides. Molecular pharmacology, 1996, Volume: 50, Issue:4 Topics: Amino Acid Sequence; Analgesics; Animals; Binding Sites; Enkephalin, Leucine; Fibroblasts; Glioma; GTP Phosphohydrolases; GTP-Binding Proteins; Hybrid Cells; Kinetics; Mice; Molecular Sequence Data; Neuroblastoma; Peptide Fragments; Protein Structure, Tertiary; Rats; Receptors, Opioid, delta; Structure-Activity Relationship; Substrate Specificity; Transfection; Tritium; Tumor Cells, Cultured	1996
The mu1 and mu2 opioid receptor binding of ketobemidone, norketobemidone and 3-dimethylamino-1,1-diphenylbutene. Pharmacology & toxicology, 1996, Volume: 79, Issue:2 Topics: Allylamine; Analgesics, Opioid; Animals; Binding, Competitive; Cattle; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Humans; Isonipecotic Acids; Meperidine; Parasympatholytics; Phenols; Receptors, Opioid, delta; Receptors, Opioid, mu	1996
Reversible affinity labeling of opioid receptors via disulfide bonding: discriminative labeling of mu and delta subtypes by chemically activated thiol-containing enkephalin analogs. Journal of biochemistry, 1996, Volume: 120, Issue:2 Topics: Affinity Labels; Animals; Binding Sites; Brain; Disulfides; Dithiothreitol; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylmaleimide; In Vitro Techniques; Kinetics; Molecular Structure; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Sulfhydryl Reagents	1996
Laminar distribution of the multiple opioid receptors in the human cerebral cortex. Neurochemical research, 1996, Volume: 21, Issue:11 Topics: Aged; Aged, 80 and over; Analgesics; Autoradiography; Benzomorphans; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Female; Humans; Male; Organ Specificity; Postmortem Changes; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium	1996
Regulation of delta-opioid receptor mRNA levels by receptor-mediated and direct activation of the adenylyl cyclase-protein kinase A pathway. Journal of neurochemistry, 1997, Volume: 68, Issue:2 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Animals; Binding Sites; Bucladesine; Calcium Channels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diprenorphine; Enkephalin, Leucine; Gene Expression Regulation, Enzymologic; Mice; Neuroblastoma; Protein Synthesis Inhibitors; Receptors, Opioid, delta; RNA, Messenger; Tritium; Tumor Cells, Cultured	1997
Determination of delta-opioid in NG108-15 cells. European journal of pharmacology, 1997, Jan-14, Volume: 319, Issue:1 Topics: Animals; Benzylidene Compounds; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Glioma; Mice; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, delta; Tumor Cells, Cultured	1997
The effect of pretreatment with a delta 2-opioid receptor antisense oligodeoxynucleotide on the recovery from acute antinociceptive tolerance to delta 2-opioid receptor agonist in the mouse spinal cord. British journal of pharmacology, 1997, Volume: 120, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Oligopeptides; Pain Measurement; Pyrrolidines; Receptors, Opioid, delta; RNA, Antisense	1997
Acute and chronic effects of opioids on delta and mu receptor activation of G proteins in NG108-15 and SK-N-SH cell membranes. Journal of neurochemistry, 1997, Volume: 68, Issue:4 Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hybrid Cells; Membrane Proteins; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neuroblastoma; Protein Binding; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Sulfur Radioisotopes; Time Factors	1997
The carboxyl terminus of mouse delta-opioid receptor is not required for agonist-dependent activation. Biochemical and biophysical research communications, 1997, Mar-17, Volume: 232, Issue:2 Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Line; CHO Cells; Cricetinae; Diprenorphine; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Humans; Kidney; Mice; Receptors, Opioid, delta; Signal Transduction; Transfection	1997
Opioids in the nucleus of the solitary tract are involved in feeding in the rat. The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 2 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Feeding Behavior; Male; Microinjections; Naltrexone; Rats; Rats, Sprague-Dawley; Solitary Nucleus	1997
Efficacy and kinetics of opioid action on acutely dissociated neurons. Molecular pharmacology, 1997, Volume: 52, Issue:1 Topics: Animals; Brimonidine Tartrate; Calcium Channels; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Etorphine; Locus Coeruleus; Morphine; Narcotics; Potassium Channels; Quinoxalines	1997
Quantitative analysis of two opioid peptides in plasma by liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of chromatography. B, Biomedical sciences and applications, 1997, Jun-20, Volume: 694, Issue:1 Topics: Animals; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Mass Spectrometry; Rats; Sensitivity and Specificity	1997
Opioid regulation of the mouse delta-opioid receptor expressed in human embryonic kidney 293 cells. Molecular pharmacology, 1997, Volume: 52, Issue:2 Topics: Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Cell Line; Colforsin; Cyclic AMP; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; GTP-Binding Proteins; Humans; Methadone; Mice; Morphine; Point Mutation; Radioligand Assay; Receptors, Opioid, delta; Signal Transduction; Structure-Activity Relationship	1997
Anatomical distribution of mu, delta, and kappa opioid- and nociceptin/orphanin FQ-stimulated [35S]guanylyl-5'-O-(gamma-thio)-triphosphate binding in guinea pig brain. The Journal of comparative neurology, 1997, Oct-06, Volume: 386, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Animals; Autoradiography; Brain Chemistry; Cerebellum; Diencephalon; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Male; Medulla Oblongata; Mesencephalon; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pons; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Telencephalon	1997
Mutagenesis of the mouse delta opioid receptor converts (-)-buprenorphine from a partial agonist to an antagonist. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:1 Topics: Analgesics, Opioid; Animals; Buprenorphine; Cells, Cultured; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Mice; Mutagenesis; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta	1998
[The use of central administration of the delta1- and delta2-opiate receptor agonists for prevention of the experimental adrenal arrhythmias]. Biulleten' eksperimental'noi biologii i meditsiny, 1997, Volume: 124, Issue:9 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Epinephrine; Injections, Intraventricular; Male; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Vagus Nerve	1997
A leu-enkephalin depresses transmission from muscle and skin non-nociceptors to first-order feline spinal neurones. The Journal of physiology, 1998, Jul-15, Volume: 510 ( Pt 2) Topics: Analgesics; Animals; Cats; Depression, Chemical; Electric Stimulation; Electrophysiology; Enkephalin, Leucine; Interneurons; Membrane Potentials; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Spinal Cord; Synaptic Transmission	1998
[Effect of opioid peptides on immunomodulation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 1998, Volume: 84, Issue:4 Topics: Animals; Cyproheptadine; Dopamine D2 Receptor Antagonists; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Haloperidol; Male; Mice; Mice, Inbred CBA; Neuroimmunomodulation; Pituitary Gland; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, Serotonin; Spleen	1998
Regulation of delta opioid receptors by delta9-tetrahydrocannabinol in NG108-15 hybrid cells. Life sciences, 1998, Volume: 63, Issue:14 Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Dronabinol; Enkephalin, Leucine; Glioma; Mice; Neuroblastoma; Piperidines; Pyrazoles; Rats; Receptors, Opioid, delta; Rimonabant; RNA, Messenger; Tumor Cells, Cultured	1998
Delta opioid receptor down-regulation is independent of functional G protein yet is dependent on agonist efficacy. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2 Topics: Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Rats; Receptors, Opioid; Tumor Cells, Cultured	1998
Role of protein kinase C (PKC) in agonist-induced mu-opioid receptor down-regulation: I. PKC translocation to the membrane of SH-SY5Y neuroblastoma cells is induced by mu-opioid agonists. Journal of neurochemistry, 1999, Volume: 72, Issue:2 Topics: Analgesics; Analgesics, Opioid; Binding, Competitive; Biological Transport; Carcinogens; Diprenorphine; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Humans; Kinetics; Membrane Proteins; Morphine; Naloxone; Narcotic Antagonists; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Opioid, mu; Second Messenger Systems; Time Factors; Tritium; Tumor Cells, Cultured	1999
Role of protein kinase C (PKC) in agonist-induced mu-opioid receptor down-regulation: II. Activation and involvement of the alpha, epsilon, and zeta isoforms of PKC. Journal of neurochemistry, 1999, Volume: 72, Issue:2 Topics: Analgesics; Analgesics, Opioid; Biological Transport; Carcinogens; Diprenorphine; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Enzyme Activation; Humans; Immunoblotting; Isoenzymes; Narcotic Antagonists; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Receptors, Opioid, mu; Second Messenger Systems; Tritium; Tumor Cells, Cultured	1999
Opioid peptide pharmacology and immunocytochemistry in an animal model of self-sustaining status epilepticus. Neuroscience, 1999, Volume: 89, Issue:1 Topics: Action Potentials; Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Immunohistochemistry; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Opioid Peptides; Peptide Fragments; Perforant Pathway; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Status Epilepticus	1999
Binding properties of C-truncated delta opioid receptors. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:4 Topics: Animals; Binding Sites; CHO Cells; Cricetinae; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Peptide Fragments; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu	1997
[The role of delta-opioid receptors in development of cardiac ischemic arrhythmia]. Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Enkephalin, Leucine; Female; Male; Myocardial Ischemia; Norepinephrine; Receptors, Opioid, delta; Vagus Nerve	1999
Antianalgesic action of dynorphin A mediated by spinal cholecystokinin. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 220, Issue:3 Topics: Analgesia; Analgesics; Animals; Antibodies; Cholecystokinin; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indoles; Injections, Spinal; Male; Meglumine; Mice; Morphine; Proglumide; Receptors, Cholecystokinin; Receptors, Opioid, delta; Spinal Cord	1999
[Effects of opioid peptides on ischemic myocardial arrhythmias during laser irradiation and disturbed heart sympathetic innervation]. Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Heart; Lasers; Male; Myocardial Ischemia; Myocardium; Opioid Peptides; Receptors, Opioid; Sympathectomy	1999
Antagonistic effect of orphanin FQ on opioid analgesia in rat. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Analgesics, Opioid; Animals; Enkephalin, Leucine; Fentanyl; Injections, Intraventricular; Injections, Spinal; Male; Nociceptin; Opioid Peptides; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Opioid	1998
Opioid agonist modulation of cytoplasmic free Ca2+ level in concanavalin A-stimulated mouse lymphocytes. Biochemistry. Biokhimiia, 1999, Volume: 64, Issue:5 Topics: Animals; Calcium; Concanavalin A; Cytoplasm; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred CBA; Peptide Fragments; Receptors, Opioid	1999
Opioids modulate cell division in the germinal zone of the late embryonic neocortex. The European journal of neuroscience, 1999, Volume: 11, Issue:8 Topics: Animals; Benzomorphans; Cell Division; Cerebral Ventricles; Embryo, Mammalian; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Female; Mice; Mice, Inbred CBA; Mitotic Index; Naloxone; Narcotic Antagonists; Narcotics; Neocortex; Pregnancy; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1999
[Modulation by the endogenous opioid system of the parasympathetic chronotropic effect on the cat heart]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 1999, Volume: 85, Issue:5 Topics: Animals; Cats; Endorphins; Enkephalin, Leucine; Heart; Heart Rate; Narcotic Antagonists; Opioid Peptides; Rabbits; Receptors, Opioid; Vagus Nerve	1999
Potentiation of transmitter release from NMB human neuroblastoma cells by kappa-opioids is mediated by N-type voltage-dependent calcium channels. Brain research, 1999, Oct-02, Volume: 843, Issue:1-2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Calcium Channel Blockers; Calcium Channels, N-Type; Dopamine; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Humans; Neuroblastoma; omega-Conotoxins; Pertussis Toxin; Potassium Cyanide; Receptors, Opioid, kappa; Tumor Cells, Cultured; Virulence Factors, Bordetella	1999
Affinity labeling of delta opioid receptors by an enkephalin-derivative alkylating agent, DSLET-Mal. Biochemical and biophysical research communications, 1999, Nov-19, Volume: 265, Issue:2 Topics: Affinity Labels; Alkylating Agents; Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Kinetics; Male; Oligopeptides; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1999
Opioids transiently prevent activation of apoptotic mechanisms following short periods of serum withdrawal. Journal of neurochemistry, 2000, Volume: 74, Issue:3 Topics: Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Benzeneacetamides; Blotting, Western; Cell Division; Culture Media, Serum-Free; Enkephalin, Leucine; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Membrane Proteins; Narcotic Antagonists; Narcotics; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Rats; Time Factors	2000
Enhancement of noradrenaline release by angiotensin II and bradykinin in mouse atria: evidence for cross-talk between G(q/11) protein- and G(i/o) protein-coupled receptors. British journal of pharmacology, 2000, Volume: 129, Issue:6 Topics: Adrenergic beta-Agonists; Angiotensin II; Angiotensin III; Animals; Atrial Function; Bradykinin; Calcium; Electric Stimulation; Electrophysiology; Enkephalin, Leucine; GTP-Binding Proteins; Heart; Heart Atria; In Vitro Techniques; Male; Mice; Myocardium; Neuropeptide Y; Norepinephrine; Receptor Cross-Talk; Receptors, Adrenergic, alpha-2; Receptors, Angiotensin; Terbutaline	2000
Protein kinase C-mediated acute tolerance to peripheral mu-opioid analgesia in the bradykinin-nociception test in mice. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2 Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Blotting, Western; Bradykinin; Dose-Response Relationship, Drug; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enzyme Inhibitors; Male; Mice; Morphine; Nociceptors; Oligonucleotides, Antisense; Pain Measurement; Peripheral Nervous System; Protein Kinase C; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu	2000
Mutation of tyrosine 318 (Y318F) in the delta-opioid receptor attenuates tyrosine phosphorylation, agonist-dependent receptor internalization, and mitogen-activated protein kinase activation. Brain research. Molecular brain research, 2000, Jun-23, Volume: 79, Issue:1-2 Topics: Amino Acid Sequence; Amino Acid Substitution; Analgesics; Animals; Cell Line; CHO Cells; Conserved Sequence; Cricetinae; Enkephalin, Leucine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Radioligand Assay; Receptors, Opioid, delta; Recombinant Proteins; Transfection; Tritium; Tyrosine	2000
Peculiarities of ischemic cardiac arrhythmias in cats against the background of stimulation of sensorimotor cortex and administration of selective opiate receptor agonists. Bulletin of experimental biology and medicine, 2000, Volume: 129, Issue:5 Topics: Analgesics, Opioid; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Motor Cortex; Myocardial Ischemia; Peptide Fragments; Receptors, Opioid	2000
Antianalgesic action of nociceptin originating in the brain is mediated by spinal prostaglandin E(2) in mice. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:1 Topics: Analgesics, Opioid; Animals; Brain; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Indomethacin; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Nociceptin; Opioid Peptides; Pain Measurement; Receptors, Prostaglandin; Spinal Cord; Substance P	2001
Characterization of opioid receptors modulating neurogenic contractions of circular muscle from porcine ileum and evidence that delta- and kappa-opioid receptors are coexpressed in myenteric neurons. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1 Topics: Amino Acid Sequence; Animals; Electric Stimulation; Enkephalin, Leucine; Goats; Ileum; In Vitro Techniques; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naltrexone; Rabbits; Receptors, Opioid, delta; Receptors, Opioid, kappa; Swine	2001
Stimulation of mu and delta-Opiate Receptors and Tolerance of Isolated Heart to Oxidative Stress: the Role of NO-Synthase. Biochemistry. Biokhimiia, 2001, Volume: 66, Issue:4 Topics: Animals; Creatine Kinase; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; In Vitro Techniques; Injections, Intravenous; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Perfusion; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Superoxide Dismutase	2001
[The role of mu- and delta-opiate receptors in resistance of the myocardium to free radical damage]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2001, Volume: 87, Issue:5 Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Myocardial Contraction; Myocardium; Oligopeptides; Oxidative Stress; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu	2001
Parallel nociceptive reflex pathways with negative and positive feedback functions to foot extensors in the cat. The Journal of physiology, 2001, Oct-15, Volume: 536, Issue:Pt 2 Topics: Analgesics; Analgesics, Opioid; Animals; Benzomorphans; Cats; Dopamine Agents; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Feedback, Physiological; Foot; Levodopa; Locomotion; Mechanoreceptors; Monoamine Oxidase Inhibitors; Muscle, Skeletal; Neural Inhibition; Nialamide; Nociceptors; Physical Stimulation; Reflex; Spinal Cord; Tibial Nerve	2001
[Role of delta opioid receptors and their ligands in the development of adaptive heart protection against arrhythmogenesis]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2001, Volume: 87, Issue:12 Topics: Adaptation, Physiological; Animals; Arrhythmias, Cardiac; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Ligands; Male; Myocardial Reperfusion Injury; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Tetrahydroisoquinolines; Thiorphan	2001
Delta opioid activation of the mitogen-activated protein kinase cascade does not require transphosphorylation of receptor tyrosine kinases. BMC pharmacology, 2002, Volume: 2 Topics: Cell Line; Enkephalin, Leucine; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Narcotics; Phosphorylation; Receptor Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Fibroblast Growth Factor; Receptors, Opioid, delta; Receptors, Platelet-Derived Growth Factor	2002
The effect of opioid agonists of delta-class DSLET, mu-class DAMGO, kappa-class U-69593 and an opioid antagonist, naloxone, on MTT activity of NALM-1 leukemic cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2002, Volume: 56, Issue:9 Topics: Benzeneacetamides; Cell Division; Cell Survival; Colorimetry; DNA Fragmentation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Humans; Leukemia; Naloxone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	2002
Effect of in vivo and in vitro stimulation of delta1-opioid receptors on myocardial resistance to arrhythmogenic action of ischemia and reperfusion. Bulletin of experimental biology and medicine, 2002, Volume: 134, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; In Vitro Techniques; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta	2002
[Effect of opioid peptides on proliferation and differentiation of skeletogenic cells of rabbit bone marrow in vitro]. Tsitologiia, 2002, Volume: 44, Issue:12 Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Fibroblasts; Hematopoietic Stem Cells; Opioid Peptides; Osteogenesis; Rabbits; Radius; Stromal Cells	2002
Activation of peripheral delta opioid receptors eliminates cardiac electrical instability in a rat model of post-infarction cardiosclerosis via mitochondrial ATP-dependent K+ channels. Life sciences, 2003, Jul-04, Volume: 73, Issue:7 Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Decanoic Acids; Disease Models, Animal; Drug Antagonism; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Glyburide; Hydroxy Acids; Male; Mitochondria, Heart; Myocardial Infarction; Myocardium; Naloxone; Potassium Channels; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, Opioid, delta; Sclerosis; Ventricular Fibrillation	2003
DSLET and ACTH(4-10) increase mitotic activity of hepatocytes and suppress antibody production. Bulletin of experimental biology and medicine, 2003, Volume: 135, Issue:5 Topics: Adrenocorticotropic Hormone; Analgesics; Animals; Antibodies; Dose-Response Relationship, Drug; Enkephalin, Leucine; Hepatocytes; Mice; Mice, Inbred CBA; Mitosis; Nootropic Agents; Peptide Fragments	2003
Interactions among mu- and delta-opioid receptors, especially putative delta1- and delta2-opioid receptors, promote dopamine release in the nucleus accumbens. Neuroscience, 2005, Volume: 135, Issue:1 Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Benzylidene Compounds; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Extracellular Space; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Tetrodotoxin	2005
Quantitative conformationally sampled pharmacophore for delta opioid ligands: reevaluation of hydrophobic moieties essential for biological activity. Journal of medicinal chemistry, 2007, Apr-19, Volume: 50, Issue:8 Topics: Animals; Cell Line, Tumor; Enkephalin, Leucine; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Conformation; Phenylalanine; Quantitative Structure-Activity Relationship; Rats; Receptors, Opioid, delta	2007
Multi-component signaling complexes of the delta-opioid receptor with STAT5B and G proteins. Neuropharmacology, 2010, Volume: 59, Issue:3 Topics: Amino Acid Sequence; Analgesics, Opioid; Cell Line, Transformed; Conserved Sequence; Enkephalin, Leucine; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Immunoprecipitation; Morphine; Mutation; Pertussis Toxin; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Pyrazoles; Pyrimidines; Receptors, Opioid, delta; Signal Transduction; STAT5 Transcription Factor; Transfection; Tyrosine	2010
Immune response of submissive and aggressive mice under conditions of opioid receptor activation. Bulletin of experimental biology and medicine, 2009, Volume: 148, Issue:6 Topics: Aggression; Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Immunomodulation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2009
Differentiation between Aδ and C fibre evoked nociceptive reflexes by TTX resistance and opioid sensitivity in the cat. Neuroscience research, 2011, Volume: 69, Issue:3 Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Animals; Cats; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Excitatory Postsynaptic Potentials; Female; Foot; Male; Naloxone; Narcotic Antagonists; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Nociceptors; Reflex; Spinal Cord; Tetrodotoxin	2011
[Role of serotonin receptors in the delta-opioid immunosuppression]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2010, Volume: 96, Issue:12 Topics: Analgesics; Animals; Enkephalin, Leucine; Immune Tolerance; Male; Mice; Mice, Inbred CBA; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Opioid, delta; Serotonin Antagonists; Serotonin Receptor Agonists	2010
Effect of opioid peptides on the content of LPO products and antioxidant enzyme activity in the liver of rats after restraint stress. Bulletin of experimental biology and medicine, 2012, Volume: 153, Issue:6 Topics: Analgesics, Opioid; Animals; Catalase; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Lipid Peroxidation; Liver; Male; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Restraint, Physical; Stress, Physiological; Superoxide Dismutase	2012
[THE INFLUENCE OF OPIOID PEPTIDES ON LIPID PEROXIDATION AND ANTIOXIDANT ENZYME ACTIVITY IN RATS AFTER SWIMMING STRESS]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2015, Volume: 101, Issue:8 Topics: Analgesics, Opioid; Animals; Catalase; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Lipid Peroxidation; Liver; Male; Rats; Rats, Wistar; Stress, Psychological; Superoxide Dismutase; Swimming	2015
Effects of Opioid Peptides on Changes in Lipid Metabolism in Rats Subjected to Swimming Stress. Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:3 Topics: Analgesics, Opioid; Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Fatty Acids, Nonesterified; Lipid Metabolism; Male; Peptide Fragments; Rats; Rats, Wistar; Stress, Psychological; Swimming; Triglycerides	2017
[THE INFLUENCE OF OPIOID PEPTIDES DSLET AND DAGO ON LIPID PEROXIDATION AND THE ACTIVITY OF ANTIOXIDANT ENZYMES IN THE LIVER TISSUE OF RATS IN THE STRESS OF DIFFERENT DURATION]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2016, Volume: 102, Issue:9 Topics: Animals; Antioxidants; Catalase; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Immobilization; Lipid Peroxidation; Liver; Male; Rats; Rats, Wistar; Stress, Psychological; Superoxide Dismutase	2016
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Molecular pharmacology, 1994, Volume: 45, Issue:2 Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software	1994
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA research monograph, 1998, Volume: 178 Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders	1998