enkephalin, leucine has been researched along with endomorphin 2 in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (39.29) | 18.2507 |
| 2000's | 14 (50.00) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Ge, LJ; Hackler, L; Kastin, AJ; Zadina, JE | 2 |
| Harrison, LM; Kastin, AJ; Zadina, JE | 1 |
| Osumi, Y; Yokotani, K | 1 |
| Bihm, CC; Burks, TF; Williams, CL | 1 |
| Cassel, JA; Daubert, JD; DeHaven, RN; Gong, J; Mansson, E; Strong, JA; Yu, G; Yu, L; Yue, X; Zhang, S | 1 |
| Mizoguchi, H; Narita, M; Sora, I; Tseng, LF; Uhl, GR | 1 |
| Balestra, B; Brecha, NC; Bunnett, NW; Grady, EF; McConalogue, K; Minnis, J; Sternini, C; Tonini, M | 1 |
| Chao, CC; Gekker, G; Hu, S; Lokensgard, J; Peterson, PK; Portoghese, PS | 1 |
| Christie, MJ; Connor, M; Pintar, JE; Schuller, A | 1 |
| Fujimura, T; Kastin, AJ; Katsuyama, S; Murayama, K; Sakurada, S; Sakurada, T; Ueda, H; Yuki, M; Zadina, JE | 1 |
| Freeman, FM; Young, IG | 1 |
| Ogren, SO; Sandin, J; Terenius, L | 1 |
| Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Narita, M; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Suzuki, T; Tan-no, K; Tseng, LF; Yuhki, M; Zadina, JE | 1 |
| Brailoiu, GC; Dun, NJ; Ohtubo, Y; Wu, SY | 1 |
| Gentilucci, L; Tolomelli, A | 1 |
| Fujimoto, JM; Leitermann, RJ; Sun, HS; Thompson, J; Tseng, LF; Wu, HE | 1 |
| Clithero, AD; Leitermann, RJ; Sun, HS; Terashvili, M; Tseng, LF; Wu, HE | 1 |
| Buschnack, SH; Kremmer, S; Muth-Selbach, U; Selbach, JM; Steuhl, KP | 1 |
| Lisi, TL; Sluka, KA | 1 |
| Cowan, A; Inan, S | 1 |
| Chen, W; Kim, W; Lao, L; Marvizón, JC; Pérez, OA; Song, B | 1 |
| Chen, W; Marvizón, JC; Song, B | 1 |
| Barna, I; Darula, Z; Kató, E; Keresztes, A; Mergl, Z; Rónai, AZ; Szemenyei, E; Tóth, G | 1 |
| Kennedy, RT; Li, Q; Zubieta, JK | 1 |
| Beaudry, F; Saidi, M | 1 |
| Appleyard, CB; Cruz, ML; Hernandez, S; Seguinot, II; Torres-Reveron, A | 1 |
| Benyhe, S; Calò, G; Della Valle, A; Minosi, P; Mollica, A; Pieretti, S; Scioli, G; Stefanucci, A; Sturaro, C; Szűcs, E; Zengin, G | 1 |
1 review(s) available for enkephalin, leucine and endomorphin 2
| Article | Year |
|---|---|
Recent advances in the investigation of the bioactive conformation of peptides active at the micro-opioid receptor. conformational analysis of endomorphins.
Topics: Binding Sites; Endorphins; Enkephalins; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Oligopeptides; Opioid Peptides; Protein Conformation; Receptors, Opioid, mu; Structure-Activity Relationship | 2004 |
27 other study(ies) available for enkephalin, leucine and endomorphin 2
| Article | Year |
|---|---|
A potent and selective endogenous agonist for the mu-opiate receptor.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Brain Chemistry; Cattle; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Mice; MSH Release-Inhibiting Hormone; Oligopeptides; Radioimmunoassay; Receptors, Opioid, mu | 1997 |
Isolation of relatively large amounts of endomorphin-1 and endomorphin-2 from human brain cortex.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Binding, Competitive; Cattle; Cerebral Cortex; Chromatography, High Pressure Liquid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Oligopeptides; Radioimmunoassay; Receptors, Opioid, mu | 1997 |
Differential effects of endomorphin-1, endomorphin-2, and Tyr-W-MIF-1 on activation of G-proteins in SH-SY5Y human neuroblastoma membranes.
Topics: Cell Membrane; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Neuroblastoma; Oligopeptides; Receptors, Opioid; Tumor Cells, Cultured | 1998 |
Involvement of mu-receptor in endogenous opioid peptide-mediated inhibition of acetylcholine release from the rat stomach.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; beta-Endorphin; Electric Stimulation; Enkephalins; Gastric Mucosa; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Rats; Receptors, Opioid, mu; Stomach; Vagus Nerve | 1998 |
Central actions of endomorphins: new endogenous opioids.
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Nociceptors; Oligopeptides; Receptors, Opioid, mu; Somatostatin; Time Factors | 1998 |
Endomorphins fully activate a cloned human mu opioid receptor.
Topics: Analgesics, Opioid; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Humans; Oligopeptides; Oocytes; Potassium Channels; Receptors, Opioid, mu; Recombinant Proteins; Transfection; Xenopus | 1998 |
Absence of G-protein activation by mu-opioid receptor agonists in the spinal cord of mu-opioid receptor knockout mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Membranes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; Morphine; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Sulfur Radioisotopes; Tritium | 1999 |
Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2.
Topics: Analgesics, Opioid; Animals; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Flow Cytometry; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neurons; Oligopeptides; Rats; Receptors, Opioid, mu; Tissue Distribution | 1999 |
Endomorphin-1 potentiates HIV-1 expression in human brain cell cultures: implication of an atypical mu-opioid receptor.
Topics: Analgesics, Opioid; Cells, Cultured; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fetus; HIV Core Protein p24; HIV-1; Humans; Kinetics; Microglia; Neuroglia; Neurons; Oligopeptides; Receptors, Opioid, mu; Virus Replication | 1999 |
Mu-opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1.
Topics: Animals; Baclofen; Calcium Channels; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Periaqueductal Gray; Receptors, Opioid, mu | 1999 |
Differential involvement of mu-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Oligopeptides; Pain; Receptors, Opioid, mu; Time Factors | 1999 |
Identification of the opioid receptors involved in passive-avoidance learning in the day-old chick during the second wave of neuronal activity.
Topics: Age Factors; Amnesia; Analgesics, Opioid; Animals; Anisomycin; Avoidance Learning; Brain Chemistry; Chickens; Chloramphenicol; Conditioning, Psychological; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Female; Male; Memory; Naltrexone; Narcotic Antagonists; Neurons; Nociceptin; Oligopeptides; Opioid Peptides; Protein Synthesis Inhibitors; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vasodilator Agents | 2000 |
Endomorphin-2 but not Leu-enkephalin modulates spatial learning when microinjected in the CA3 region of the rat hippocampus.
Topics: Animals; Enkephalin, Leucine; Hippocampus; Male; Maze Learning; Microinjections; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 2000 |
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.
Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Time Factors | 2001 |
Effects of endomorphin on substantia gelatinosa neurons in rat spinal cord slices.
Topics: Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Postsynaptic Potentials; Female; Male; Membrane Potentials; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Substantia Gelatinosa; Tetrodotoxin; Time Factors | 2003 |
Nonopioidergic mechanism mediating morphine-induced antianalgesia in the mouse spinal cord.
Topics: Analgesia; Animals; beta-Endorphin; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Dynorphins; Enkephalins; Male; Mice; Morphine; Naloxone; Naltrexone; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substance P | 2004 |
Differential mechanisms of antianalgesia induced by endomorphin-1 and endomorphin-2 in the ventral periaqueductal gray of the rat.
Topics: Analgesia; Animals; beta-Endorphin; Cholecystokinin; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Receptors, Opioid, mu; Substance P | 2005 |
Substance P and opioid peptidergic innervation of the anterior eye segment of the rat: an immunohistochemical study.
Topics: Animals; Anterior Eye Segment; Ciliary Body; Conjunctiva; Cornea; Enkephalin, Leucine; Enkephalin, Methionine; Immunohistochemistry; Iris; Nociceptin; Oligopeptides; Opioid Peptides; Rats; Rats, Sprague-Dawley; Sclera; Substance P; Trabecular Meshwork | 2005 |
A new electrochemical HPLC method for analysis of enkephalins and endomorphins.
Topics: Animals; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Male; Microdialysis; Oligopeptides; Pain; Perfusion; Posterior Horn Cells; Potassium Chloride; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 2006 |
Reduced kappa-opioid activity in a rat model of cholestasis.
Topics: Animals; Binding, Competitive; Brain; Cholestasis; Dialysis Solutions; Disease Models, Animal; Dynorphins; Enkephalin, Leucine; Guanosine 5'-O-(3-Thiotriphosphate); Hypothalamus; Male; Microdialysis; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sulfur Radioisotopes | 2005 |
Comparing analgesia and mu-opioid receptor internalization produced by intrathecal enkephalin: requirement for peptidase inhibition.
Topics: Analgesia; Animals; Data Interpretation, Statistical; Enkephalins; Immunohistochemistry; Injections, Spinal; Male; Microscopy, Confocal; Oligopeptides; Pain Measurement; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, mu | 2007 |
Inhibition of opioid release in the rat spinal cord by alpha2C adrenergic receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Brimonidine Tartrate; Clonidine; Data Interpretation, Statistical; Electric Stimulation; Enkephalins; Guanfacine; Immunohistochemistry; Male; Medetomidine; Microscopy, Confocal; Oligopeptides; Protease Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Spinal Cord; Veratridine | 2008 |
Detection of a novel immunoreactive endomorphin 2-like peptide in rat brain extracts.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Enkephalins; Immune Sera; Male; Mice; Narcotic Antagonists; Oligopeptides; Peptides; Rabbits; Radioimmunoassay; Rats; Rats, Wistar | 2008 |
Practical aspects of in vivo detection of neuropeptides by microdialysis coupled off-line to capillary LC with multistage MS.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Corpus Striatum; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Limit of Detection; Male; Microdialysis; Neuropeptides; Oligopeptides; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization | 2009 |
Liquid chromatography-electrospray linear ion trap mass spectrometry analysis of targeted neuropeptides in Tac1(-/-) mouse spinal cords reveals significant lower concentration of opioid peptides.
Topics: Animals; Chromatography, Liquid; Dynorphins; Enkephalin, Leucine; Male; Mice; Mice, Inbred C57BL; Neuropeptides; Oligopeptides; Spectrometry, Mass, Electrospray Ionization; Spinal Cord; Tachykinins | 2015 |
Impact of Psychological Stress on Pain Perception in an Animal Model of Endometriosis.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Endometriosis; Enkephalins; Female; Oligopeptides; Pain Measurement; Pain Perception; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, mu; Spinal Cord; Stress, Psychological; Substance P | 2017 |
Selective MOR activity of DAPEA and Endomorphin-2 analogues containing a (R)-γ-Freidinger lactam in position two.
Topics: Amides; Animals; Dose-Response Relationship, Drug; Enkephalins; Infusions, Intraventricular; Lactams; Mice; Molecular Docking Simulation; Molecular Structure; Oligopeptides; Receptors, Opioid, mu; Structure-Activity Relationship | 2021 |