enkephalin, leucine has been researched along with endomorphin 1 in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (53.33) | 18.2507 |
| 2000's | 11 (36.67) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ardá, A; Arsequell, G; Barreto-Valer, K; Caltabiano, G; Gómez-Tamayo, JC; Gonzalez-Nunez, V; Jiménez-Barbero, J; Pardo, L; Rodríguez, RE; Rosa, M; Valencia, G | 1 |
| Ge, LJ; Hackler, L; Kastin, AJ; Zadina, JE | 2 |
| Childers, SR; Liu, Q; Selley, DE; Sim, LJ | 1 |
| Burford, NT; Sadee, W; Tolbert, LM | 1 |
| Harrison, LM; Kastin, AJ; Zadina, JE | 1 |
| Fujimura, T; Kakizawa, K; Murayama, K; Sakurada, S; Shimohira, I; Ueda, H | 1 |
| Osumi, Y; Yokotani, K | 1 |
| Bihm, CC; Burks, TF; Williams, CL | 1 |
| Cassel, JA; Daubert, JD; DeHaven, RN; Gong, J; Mansson, E; Strong, JA; Yu, G; Yu, L; Yue, X; Zhang, S | 1 |
| Bivalacqua, TJ; Champion, HC; Friedman, DE; Kadowitz, PJ; Kastin, AJ; Zadina, JE | 1 |
| Mizoguchi, H; Narita, M; Sora, I; Tseng, LF; Uhl, GR | 1 |
| Balestra, B; Brecha, NC; Bunnett, NW; Grady, EF; McConalogue, K; Minnis, J; Sternini, C; Tonini, M | 1 |
| Chao, CC; Gekker, G; Hu, S; Lokensgard, J; Peterson, PK; Portoghese, PS | 1 |
| Christie, MJ; Connor, M; Pintar, JE; Schuller, A | 1 |
| Fujimura, T; Kastin, AJ; Katsuyama, S; Murayama, K; Sakurada, S; Sakurada, T; Ueda, H; Yuki, M; Zadina, JE | 1 |
| Fujibayashi, K; Kubota, K; Saito, K; Sugimoto-Watanabe, A | 1 |
| Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Narita, M; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Suzuki, T; Tan-no, K; Tseng, LF; Yuhki, M; Zadina, JE | 1 |
| Eguchi, M; Kahn, M; Lee, MS; Shea, JP; Shen, RY | 1 |
| Asano, A; Doi, M; Komura, E; Ueda, Y | 1 |
| Brailoiu, GC; Dun, NJ; Ohtubo, Y; Wu, SY | 1 |
| Gentilucci, L; Tolomelli, A | 1 |
| Clithero, AD; Leitermann, RJ; Sun, HS; Terashvili, M; Tseng, LF; Wu, HE | 1 |
| Buschnack, SH; Kremmer, S; Muth-Selbach, U; Selbach, JM; Steuhl, KP | 1 |
| Lisi, TL; Sluka, KA | 1 |
| Bey, V; Burkey, AR; Commons, KG; Evans, JM | 1 |
| Blanchfield, JT; Del Borgo, MP; Toth, I | 1 |
| Kennedy, RT; Li, Q; Zubieta, JK | 1 |
| Balchen, M; Lund, H; Pedersen-Bjergaard, S; Reubsaet, L | 1 |
| Liu, X; Ma, M; Wang, K; Wang, R; Wang, Y; Wei, S; Zhang, X; Zhao, L; Zhou, J | 1 |
1 review(s) available for enkephalin, leucine and endomorphin 1
| Article | Year |
|---|---|
Recent advances in the investigation of the bioactive conformation of peptides active at the micro-opioid receptor. conformational analysis of endomorphins.
Topics: Binding Sites; Endorphins; Enkephalins; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Oligopeptides; Opioid Peptides; Protein Conformation; Receptors, Opioid, mu; Structure-Activity Relationship | 2004 |
29 other study(ies) available for enkephalin, leucine and endomorphin 1
| Article | Year |
|---|---|
Modulation of the Interaction between a Peptide Ligand and a G Protein-Coupled Receptor by Halogen Atoms.
Topics: | 2015 |
A potent and selective endogenous agonist for the mu-opiate receptor.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Brain Chemistry; Cattle; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Mice; MSH Release-Inhibiting Hormone; Oligopeptides; Radioimmunoassay; Receptors, Opioid, mu | 1997 |
Isolation of relatively large amounts of endomorphin-1 and endomorphin-2 from human brain cortex.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Binding, Competitive; Cattle; Cerebral Cortex; Chromatography, High Pressure Liquid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Oligopeptides; Radioimmunoassay; Receptors, Opioid, mu | 1997 |
Endomorphin-stimulated [35S]GTPgammaS binding in rat brain: evidence for partial agonist activity at mu-opioid receptors.
Topics: Animals; Autoradiography; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Male; Naloxone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sulfur Radioisotopes | 1998 |
Specific G protein activation and mu-opioid receptor internalization caused by morphine, DAMGO and endomorphin I.
Topics: Analgesics, Opioid; Biotransformation; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Microscopy, Confocal; Morphine; Oligopeptides; Receptors, Opioid, mu | 1998 |
Differential effects of endomorphin-1, endomorphin-2, and Tyr-W-MIF-1 on activation of G-proteins in SH-SY5Y human neuroblastoma membranes.
Topics: Cell Membrane; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Neuroblastoma; Oligopeptides; Receptors, Opioid; Tumor Cells, Cultured | 1998 |
Parallel stimulations of in vitro and in situ [35S]GTPgammaS binding by endomorphin 1 and DAMGO in mouse brains.
Topics: Amygdala; Animals; Autoradiography; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Male; Mice; Oligopeptides; Receptors, Opioid, mu; Synaptic Membranes | 1998 |
Involvement of mu-receptor in endogenous opioid peptide-mediated inhibition of acetylcholine release from the rat stomach.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; beta-Endorphin; Electric Stimulation; Enkephalins; Gastric Mucosa; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Rats; Receptors, Opioid, mu; Stomach; Vagus Nerve | 1998 |
Central actions of endomorphins: new endogenous opioids.
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Nociceptors; Oligopeptides; Receptors, Opioid, mu; Somatostatin; Time Factors | 1998 |
Endomorphins fully activate a cloned human mu opioid receptor.
Topics: Analgesics, Opioid; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Humans; Oligopeptides; Oocytes; Potassium Channels; Receptors, Opioid, mu; Recombinant Proteins; Transfection; Xenopus | 1998 |
Nitric oxide release mediates vasodilator responses to endomorphin 1 but not nociceptin/OFQ in the hindquarters vascular bed of the rat.
Topics: Adamantane; Animals; Blood Vessels; Endorphins; Endothelium, Vascular; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Meclofenamic Acid; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptin; Oligopeptides; Opioid Peptides; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Regional Blood Flow; Vasodilation; Vasodilator Agents | 1998 |
Absence of G-protein activation by mu-opioid receptor agonists in the spinal cord of mu-opioid receptor knockout mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Membranes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; Morphine; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Sulfur Radioisotopes; Tritium | 1999 |
Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2.
Topics: Analgesics, Opioid; Animals; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Flow Cytometry; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neurons; Oligopeptides; Rats; Receptors, Opioid, mu; Tissue Distribution | 1999 |
Endomorphin-1 potentiates HIV-1 expression in human brain cell cultures: implication of an atypical mu-opioid receptor.
Topics: Analgesics, Opioid; Cells, Cultured; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fetus; HIV Core Protein p24; HIV-1; Humans; Kinetics; Microglia; Neuroglia; Neurons; Oligopeptides; Receptors, Opioid, mu; Virus Replication | 1999 |
Mu-opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1.
Topics: Animals; Baclofen; Calcium Channels; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Periaqueductal Gray; Receptors, Opioid, mu | 1999 |
Differential involvement of mu-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Oligopeptides; Pain; Receptors, Opioid, mu; Time Factors | 1999 |
Antinociceptive effect and enzymatic degradation of endomorphin-1 in newborn rat spinal cord.
Topics: Animals; Animals, Newborn; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Female; Hydrolysis; Membrane Potentials; Oligopeptides; Pregnancy; Protease Inhibitors; Rats; Rats, Wistar; Spinal Cord | 1999 |
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.
Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Time Factors | 2001 |
Design, synthesis, and evaluation of opioid analogues with non-peptidic beta-turn scaffold: enkephalin and endomorphin mimetics.
Topics: Enkephalins; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Naloxone; Narcotics; Oligopeptides; Peptide Biosynthesis; Peptide Library; Peptides; Protein Conformation; Protein Structure, Secondary; Receptors, Opioid; Time Factors | 2002 |
The structure of an endomorphin analogue incorporating 1-aminocyclohexane-1-carboxlylic acid for proline is similar to the beta-turn of Leu-enkephalin.
Topics: Amino Acids, Cyclic; Cyclohexanecarboxylic Acids; Enkephalin, Leucine; Models, Molecular; Oligopeptides; Proline; Protein Structure, Secondary | 2002 |
Effects of endomorphin on substantia gelatinosa neurons in rat spinal cord slices.
Topics: Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Postsynaptic Potentials; Female; Male; Membrane Potentials; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Substantia Gelatinosa; Tetrodotoxin; Time Factors | 2003 |
Differential mechanisms of antianalgesia induced by endomorphin-1 and endomorphin-2 in the ventral periaqueductal gray of the rat.
Topics: Analgesia; Animals; beta-Endorphin; Cholecystokinin; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Receptors, Opioid, mu; Substance P | 2005 |
Substance P and opioid peptidergic innervation of the anterior eye segment of the rat: an immunohistochemical study.
Topics: Animals; Anterior Eye Segment; Ciliary Body; Conjunctiva; Cornea; Enkephalin, Leucine; Enkephalin, Methionine; Immunohistochemistry; Iris; Nociceptin; Oligopeptides; Opioid Peptides; Rats; Rats, Sprague-Dawley; Sclera; Substance P; Trabecular Meshwork | 2005 |
A new electrochemical HPLC method for analysis of enkephalins and endomorphins.
Topics: Animals; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Male; Microdialysis; Oligopeptides; Pain; Perfusion; Posterior Horn Cells; Potassium Chloride; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 2006 |
Organization of endogenous opioids in the rostral agranular insular cortex of the rat.
Topics: Animals; Axons; Cerebral Cortex; Enkephalins; gamma-Aminobutyric Acid; Immunohistochemistry; Interneurons; Male; Neural Inhibition; Neural Pathways; Neurons; Oligopeptides; Opioid Peptides; Pro-Opiomelanocortin; Protein Precursors; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 2007 |
Internalisation of the mu-opioid receptor by endomorphin-1 and leu-enkephalin is dependant on aromatic amino acid residues.
Topics: Amino Acids, Aromatic; Cell Line; Chromatography, High Pressure Liquid; Cyclic AMP; Enkephalin, Leucine; Humans; Oligopeptides; Receptors, Opioid, mu; Spectrometry, Mass, Electrospray Ionization | 2008 |
Practical aspects of in vivo detection of neuropeptides by microdialysis coupled off-line to capillary LC with multistage MS.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Corpus Striatum; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Limit of Detection; Male; Microdialysis; Neuropeptides; Oligopeptides; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization | 2009 |
Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane extraction.
Topics: 1-Octanol; Angiotensin II; Chromatography, High Pressure Liquid; Diethylhexyl Phthalate; Electrodes; Enkephalin, Leucine; Humans; Ketones; Membranes, Artificial; Oligopeptides; Peptides; Tandem Mass Spectrometry | 2012 |
Contribution of the μ opioid receptor and enkephalin to the antinociceptive actions of endomorphin-1 analogs with unnatural amino acid modifications in the spinal cord.
Topics: Analgesics; Animals; Chronic Pain; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Mice; Naloxone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, mu; Spinal Cord | 2021 |