enkephalin, leucine has been researched along with dizocilpine maleate in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 21 (72.41) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM | 1 |
| Beal, MF; Penney, JB; Wüllner, U; Young, AB | 1 |
| Bernard, V; Bloch, B; Lannes, B; Micheletti, G | 1 |
| Angulo, JA; Ledoux, M; McEwen, BS; Watanabe, Y; Williams, A | 1 |
| Kim, YH; Song, DK; Suh, HW; Tseng, LF; Yoo, JS | 1 |
| Angulo, JA; Cadet, J; Ledoux, M; McEwen, BS; Watanabe, Y | 1 |
| Albala, N; Van Bree, L; Vanderhaeghen, JJ; Verslype, M; Zhang, F | 1 |
| Hajji, MD; Kerkerian-Le Goff, L; Salin, P | 1 |
| Höllt, V; Ziółkowska, B | 1 |
| Bhargava, HN; Zhao, GM | 1 |
| Angulo, JA; Ledoux, M; Lucas, LR; McEwen, BS; Noailles, PA; Villegas, M | 1 |
| Cherng, CH; Ho, ST; Luk, HN; Tung, CS; Wong, CS | 1 |
| Bharagava, HN; Zhao, GM | 1 |
| Bilsky, EJ; Hruby, VJ; Inturrisi, CE; Porreca, F; Sadée, W | 1 |
| Bontempi, B; Sharp, FR | 1 |
| Bhargava, HN; Bian, JT; Cao, YJ | 1 |
| Bhargava, HN; Bian, JT; Kumar, S | 1 |
| Lu, J; Mao, J; Mayer, DJ; Price, DD | 1 |
| Arcaya, JL; Cano, G; Gómez, G; Maixner, W; Suárez-Roca, H | 1 |
| Caruncho, HJ; Labandeira-Garcia, JL; Liste, I; Rodriguez-Pallares, J | 1 |
| Kolesnikov, Y; Pasternak, GW | 1 |
| Guerra, MJ; Labandeira-Garcia, JL; Liste, I; Muñoz, A | 1 |
| Bordet, R; Ridray, S; Schwartz, JC; Sokoloff, P | 1 |
| Groenewegen, HJ; Van De Witte, SV; Voorn, P | 1 |
| Bakalkin, G; Esashi, A; Kisara, K; Nakagawasai, O; Niijima, F; Sakurada, C; Sakurada, T; Tadano, T; Tan-No, K; Terenius, L | 1 |
| Bonastre, M; Hirsch, EC; Marin, C; Périer, C; Tolosa, E | 1 |
| Fujimoto, JM; Leitermann, RJ; Sun, HS; Thompson, J; Tseng, LF; Wu, HE | 1 |
| Bakalkin, G; Marinova, Z; Nakagawasai, O; Niijima, F; Sakurada, S; Sato, T; Satoh, S; Tadano, T; Takahashi, H; Tan-No, K; Terenius, L; Yakovleva, T | 1 |
| Gerfen, CR; Hasegawa, YT; Miyachi, S | 1 |
29 other study(ies) available for enkephalin, leucine and dizocilpine maleate
| Article | Year |
|---|---|
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
3-Nitropropionic acid toxicity in the striatum.
Topics: Animals; Antihypertensive Agents; Base Sequence; Corpus Striatum; Dizocilpine Maleate; DNA; Dose-Response Relationship, Drug; Enkephalins; Gene Expression; Glial Fibrillary Acidic Protein; Histocytochemistry; In Situ Hybridization; Ligands; Male; Molecular Sequence Data; Naloxone; Neurons; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatostatin; Substance P; Tritium | 1994 |
Chronic treatment with dizocilpine maleate increases the number of striatal neurons expressing the D2 receptor gene.
Topics: Animals; Dizocilpine Maleate; DNA Probes; Enkephalins; In Situ Hybridization; Male; Neostriatum; Neurons; Nucleus Accumbens; Protein Precursors; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance P | 1995 |
Elevation of striatal and accumbal preproenkephalin, preprotachykinin and preprodynorphin mRNA abundance subsequent to N-methyl-D-aspartate receptor blockade with MK-801.
Topics: Animals; Base Sequence; Corpus Striatum; Dizocilpine Maleate; Dynorphins; Enkephalins; Male; Molecular Probes; Molecular Sequence Data; Neuropeptides; Nucleus Accumbens; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tachykinins | 1995 |
Differential antagonism by MK-801 against antinociception induced by opioid receptor agonists administered supraspinally in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; beta-Endorphin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Pyrrolidines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid | 1994 |
Upregulation of forebrain proenkephalin mRNA subsequent to NMDA receptor blockade.
Topics: Animals; Base Sequence; Dizocilpine Maleate; Enkephalins; Male; Molecular Sequence Data; Neostriatum; Nucleus Accumbens; Prosencephalon; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Up-Regulation | 1993 |
NMDA receptor antagonist MK-801 down-regulates rat striatal proenkephalin and protachykinin mRNAs.
Topics: Animals; Autoradiography; Dizocilpine Maleate; Down-Regulation; Enkephalins; Excitatory Amino Acid Antagonists; In Situ Hybridization; Injections, Intraperitoneal; Male; Neostriatum; Protein Precursors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tachykinins | 1996 |
Chronic dizocilpine maleate (MK-801) treatment suppresses the effects of nigrostriatal dopamine deafferentation on enkephalin but not on substance P expression in the rat striatum.
Topics: Afferent Pathways; Animals; Base Sequence; Corpus Striatum; Dizocilpine Maleate; Dopamine; Enkephalins; Excitatory Amino Acid Antagonists; Female; In Situ Hybridization; Molecular Sequence Data; Neuroprotective Agents; Oligonucleotide Probes; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substance P; Substantia Nigra | 1996 |
Fos is not involved in the regulation of the proenkephalin gene by haloperidol in the mouse striatum.
Topics: Analysis of Variance; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enkephalins; Gene Expression Regulation; Genes, fos; Haloperidol; Male; Mice; Mice, Inbred Strains; Protein Precursors | 1995 |
Effect of antagonism of the NMDA receptor on tolerance to [D-Pen2,D-Pen5]enkephalin, a delta 1-opioid receptor agonist.
Topics: Analgesics; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Isoquinolines; Male; Mice; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta | 1996 |
Acute treatment with the N-methyl-D-aspartate receptor antagonist MK-801: effect of concurrent administration of haloperidol or scopolamine on preproenkephalin mRNA levels of the striatum and nucleus accumbens of the rat brain.
Topics: Animals; Base Sequence; Brain Chemistry; Dizocilpine Maleate; Dopamine Antagonists; Enkephalins; Excitatory Amino Acid Antagonists; Haloperidol; In Situ Hybridization; Male; Molecular Sequence Data; Muscarinic Antagonists; Neostriatum; Nucleus Accumbens; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Scopolamine | 1996 |
Effects of NMDA receptor antagonists on inhibition of morphine tolerance in rats: binding at mu-opioid receptors.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Analgesics, Opioid; Animals; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Morphine; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Spinal Cord | 1996 |
Effects of competitive and noncompetitive antagonists of the N-methyl-D-aspartate receptor on the analgesic action of delta 1- and delta 2-opioid receptor agonists in mice.
Topics: Analgesics, Opioid; Animals; Antiparkinson Agents; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Isoquinolines; Male; Membranes; Mice; Oligopeptides; Pain Measurement; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta | 1996 |
Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective mu or delta opioid agonists in mice.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Dizocilpine Maleate; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Fentanyl; Isoquinolines; Male; Mice; Mice, Inbred ICR; Morphine; Oligopeptides; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, mu | 1996 |
Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area.
Topics: Afferent Pathways; Analgesics, Opioid; Animals; Behavior, Animal; Benzazepines; Bicuculline; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Injections; Injections, Intraperitoneal; Interneurons; Morphine; Motor Activity; Naloxone; Nerve Tissue Proteins; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substantia Nigra; Tegmentum Mesencephali | 1997 |
Effects of NMDA receptor antagonists on delta1- and delta2-opioid receptor agonists-induced changes in the mouse brain [3H]DPDPE binding.
Topics: Animals; Brain; Dizocilpine Maleate; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Membranes; Mice; Oligopeptides; Protein Binding; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta | 1997 |
Up-regulation of brain N-methyl-D-aspartate receptors following multiple intracerebroventricular injections of [D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin II in mice.
Topics: Animals; Brain; Dizocilpine Maleate; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mice; Oligopeptides; Protein Binding; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Up-Regulation | 1997 |
Antinociceptive tolerance to the mu-opioid agonist DAMGO is dose-dependently reduced by MK-801 in rats.
Topics: Analgesics; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1998 |
Dynorphin A increases substance P release from trigeminal primary afferent C-fibers.
Topics: Animals; Animals, Newborn; Capsaicin; Dizocilpine Maleate; Dynorphins; Enkephalin, Leucine; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance P; Trigeminal Nuclei | 1999 |
Locomotor-activity-induced changes in striatal levels of preprotachykinin and preproenkephalin mRNA. Regulation by the dopaminergic and glutamatergic systems.
Topics: Animals; Apomorphine; Benzazepines; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Enkephalins; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Glutamic Acid; In Situ Hybridization; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Running; Tachykinins | 1999 |
Topical opioids in mice: analgesia and reversal of tolerance by a topical N-methyl-D-aspartate antagonist.
Topics: Administration, Topical; Analgesics, Opioid; Animals; Brain; Dizocilpine Maleate; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Derivatives; Pain Measurement; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tail; Tissue Distribution | 1999 |
Fenfluramine-induced increase in preproenkephalin mRNA levels in the striatum: interaction between the serotonergic, glutamatergic, and dopaminergic systems.
Topics: 5,7-Dihydroxytryptamine; Adrenergic Agents; Animals; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Enkephalins; Female; Fenfluramine; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serotonin Agents | 2000 |
Involvement of the direct striatonigral pathway in levodopa-induced sensitization in 6-hydroxydopamine-lesioned rats.
Topics: Animals; Antiparkinson Agents; Benzazepines; Binding, Competitive; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Enkephalins; Excitatory Amino Acid Antagonists; Gene Expression; Levodopa; Male; Neural Pathways; Neurons; Opioid Peptides; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Substantia Nigra; Sympatholytics; Tachykinins; Tetrahydronaphthalenes; Tritium; Ventral Tegmental Area | 2000 |
MK-801 alters the effects of priming with L-DOPA on dopamine D1 receptor-induced changes in neuropeptide mRNA levels in the rat striatal output neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Drug Interactions; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Immunohistochemistry; Levodopa; Male; Motor Activity; Neostriatum; Neurons; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tachykinins; Tyrosine 3-Monooxygenase | 2002 |
Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Behavior, Animal; Dizocilpine Maleate; Dynorphins; Endorphins; Enkephalins; Excitatory Amino Acid Antagonists; Injections, Spinal; Kynurenic Acid; Male; Mice; Morphine; Neurokinin A; Nociceptors; Peptide Fragments; Piperidines; Protein Precursors; Receptors, N-Methyl-D-Aspartate; Receptors, Tachykinin; Substance P | 2002 |
AMPA receptor antagonist LY293558 reverses preproenkephalin mRNA overexpression in the striatum of 6-OHDA-lesioned-rats treated with L-dopa.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Isoquinolines; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tetrazoles | 2002 |
Nonopioidergic mechanism mediating morphine-induced antianalgesia in the mouse spinal cord.
Topics: Analgesia; Animals; beta-Endorphin; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Dynorphins; Enkephalins; Male; Mice; Morphine; Naloxone; Naltrexone; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substance P | 2004 |
Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation.
Topics: Agmatine; Analysis of Variance; Animals; Behavior, Animal; Biguanides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Enkephalins; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Antagonists; Immune Sera; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Narcotics; Nociceptin Receptor; Piperidines; Protein Precursors; Receptors, Opioid; Spinal Cord; Time Factors | 2005 |
Coincident stimulation of convergent cortical inputs enhances immediate early gene induction in the striatum.
Topics: AIDS-Related Complex; Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Radiation; Electric Stimulation; Enkephalins; Excitatory Amino Acid Antagonists; Functional Laterality; Gene Expression; Genes, fos; Genes, Immediate-Early; In Situ Hybridization; Male; Motor Cortex; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2005 |