enkephalin, leucine has been researched along with dihydromorphine in 76 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 69 (90.79) | 18.7374 |
1990's | 7 (9.21) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Somoza, E | 1 |
Kosterlitz, HW; Robson, LE | 1 |
Kuhar, MJ; Young, WS | 1 |
Corbett, AD; Gillan, MG; Kosterlitz, HW; McKnight, AT; Paterson, SJ; Robson, LE; Sosa, RP | 1 |
Kosterlitz, HW; Leslie, FM | 1 |
Law, PY; Loh, HH | 1 |
Borsodi, A; Búzás, B; Cavagnero, S; Hruby, VJ; Tóth, G | 1 |
Barg, J; Belcheva, MM; Bem, WT; Coscia, CJ; Loh, YP; Rius, RA | 1 |
Kuhar, MJ; Wamsley, JK; Zarbin, MA | 1 |
Galetta, S; Hahn, EF; Nishimura, S; Pasternak, GW | 1 |
Garzón, J; Sánchez-Blázquez, P | 1 |
Garzon, J; Landahl, HD; Lee, NM | 1 |
Pasternak, GW; Recht, LD | 1 |
De Souza, EB; Kuhar, MJ; Schmidt, WK | 1 |
Gramsch, C; Herz, A; Kosin, S; Schulz, R | 1 |
Ishizuka, Y; Oka, T | 1 |
Bolger, GT; Rice, KC; Skolnick, P; Weissman, BA | 1 |
Barnard, EA; Demoliou-Mason, CD | 2 |
Pasternak, GW; Wood, PJ | 1 |
Archer, S; Maneckjee, R; Michael, J; Osei-Gyimah, P; Zukin, RS | 1 |
Hammonds, RG; Ho, CL; Li, CH | 1 |
Ensinger, HA | 1 |
Neil, A | 2 |
Gottlieb, DI; Mattler, JA; Slaughter, MM | 1 |
Hirobe, M; Konno, F; Sato, Y; Takayanagi, I; Togashi, K | 1 |
Goodman, RR; Pasternak, GW | 1 |
Bidlack, JM; Denton, RR | 1 |
Goodman, RR; Moskowitz, AS | 1 |
Pasternak, GW | 2 |
Christ, GJ; Dunlap, CE; Rose, JC | 1 |
Blurton, PA; Broadhurst, AM; Wood, MD; Wyllie, MG | 1 |
Gardner, EL; Vaysse, PJ; Zukin, RS | 1 |
Geladopoulos, T; Sakellaridis, N; Vernadakis, A | 1 |
Itzhak, Y; Simon, EJ | 1 |
Antkiewicz-Michaluk, L; Havemann, U; Kuschinsky, K; Vetulani, J; Wellstein, A | 1 |
Chung, CT; Hoffman, PL; Tabakoff, B | 1 |
Hirobe, M; Konno, F; Shibata, R; Takayanagi, I | 1 |
Matsui, H; Yamamoto, C | 1 |
Loh, HH; Stokes, KB | 1 |
Airaksinen, MM; Gynther, J; Huhtikangas, A; Juvonen, H; Saano, V; Steidel, E | 1 |
Burkard, WP; Flück, N; Müller, PM | 1 |
Gintzler, AR; Zukin, RS | 1 |
Chavkin, C; Cox, BM; Leslie, FM | 2 |
Chang, JK; Chang, KJ; Cuatrecasas, P; Hazum, E; Lillian, A | 1 |
Gillan, MG; Kosterlitz, HW; Kriwaczek, VM; Paterson, SJ; Schwyzer, R | 1 |
Byrne, WL; Codd, EE | 1 |
Kosterlitz, HW; Paterson, SJ; Robson, LE | 1 |
Banay-Schwartz, M; Lajtha, A; Manigault, I; Wajda, IJ | 1 |
Lajtha, A; Reith, ME; Sershen, H; Vadasz, C | 1 |
Egan, TM; North, RA | 1 |
Costa, T; Shimohigashi, Y; Stammer, CH | 1 |
Ferrara, P; Li, CH | 1 |
Snyder, SH | 1 |
Nishimura, S; Pasternak, GW; Wolozin, BL | 1 |
Cox, BM; Ho, WK | 1 |
Kouakou, Y; Meunier, JC; Moisand, C; Zajac, JM | 1 |
Shimohigashi, Y; Stammer, CH | 1 |
Fitz-Syage, ML; Gardner, EL; Gintzler, AR; Sugarman, JR; Zukin, RS; Zukin, SR | 1 |
Nishimura, S; Pasternak, GW | 1 |
Guidotti, A; Saiani, L | 1 |
Attali, B; Audigier, Y; Cros, J; Gouardères, C; Mazarguil, H | 1 |
Johnson, N; Pasternak, GW | 1 |
Garzon, J; Jen, MF; Lee, NM; Loh, HH | 1 |
Govoni, S; Lucchi, L; Rius, RA; Trabucchi, M; Uzumaki, H | 1 |
Nishimura, SL; Pasternak, GW; Recht, LD | 1 |
Barg, J; Lenoir, D; Simantov, R | 1 |
Gianoulakis, C | 1 |
Fukushima, M; Furui, T; Haga, T; Ichiyama, A; Kageyama, N | 1 |
Cabon, F; Morser, J; Parmantier, E; Pham-Dinh, D; Solly, SK; Zalc, B | 1 |
Bilfinger, TV; Casares, F; Goligorsky, MS; Hartman, A; Liu, Y; Magazine, HI; Stefano, GB | 1 |
Casulari, LA; Maggi, R; Martini, L; Pimpinelli, F; Piva, F | 1 |
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
2 review(s) available for enkephalin, leucine and dihydromorphine
Article | Year |
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Multiple mu opiate receptors.
Topics: Aging; Analgesia; Animals; Autoradiography; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylmaleimide; Morphine; Naloxone; Neurotransmitter Agents; Phylogeny; Receptors, Opioid; Receptors, Opioid, mu; Respiration; Substance-Related Disorders; Tissue Distribution | 1986 |
Characteristics of peptide and alkaloid opiate binding sites in brain and peripheral tissues.
Topics: Adrenal Medulla; Animals; Brain; Corpus Striatum; Dihydromorphine; Endorphins; Enkephalins; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Receptors, Opioid; Vas Deferens | 1980 |
74 other study(ies) available for enkephalin, leucine and dihydromorphine
Article | Year |
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Influence of neuroleptics on the binding of met-enkephalin, morphine and dihydromorphine to synaptosome-enriched fractions of rat brain.
Topics: Animals; Antipsychotic Agents; Brain; Dihydromorphine; Endorphins; Enkephalins; Female; In Vitro Techniques; Kinetics; Mitochondria; Morphine; Morphine Derivatives; Rats; Receptors, Opioid; Synaptosomes | 1978 |
Specific protection of the binding sites of D-Ala2-D-Leu5-enkephalin (delta-receptors) and dihydromorphine (mu-receptors).
Topics: Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalins; Guinea Pigs; Kinetics; Ligands; Morphine Derivatives; Receptors, Opioid; Structure-Activity Relationship | 1979 |
A new method for receptor autoradiography: [3H]opioid receptors in rat brain.
Topics: Animals; Autoradiography; Brain; Corpus Striatum; Dihydromorphine; Diprenorphine; Enkephalins; Frontal Lobe; Guanosine Triphosphate; Histological Techniques; Male; Rats; Receptors, Opioid; Sodium; Tritium | 1979 |
Biosynthesis of the enkephalins in the myenteric plexus of the guinea pig ileum: further analysis of the interaction of the enkephalins and their analogues with the opiate receptors.
Topics: Animals; Binding Sites; Brain; Cycloheximide; Dihydromorphine; Endorphins; Enkephalins; Guinea Pigs; Ileum; Myenteric Plexus; Naloxone; Receptors, Opioid; Trypsin | 1979 |
Comparison of binding of [3H]-methionine-enkephalin, [3H]-naltrexone and [3H]-dihydromorphine in the mouse vas deferens and the myenteric plexus and brain of the ginea pig.
Topics: Animals; Brain; Dihydromorphine; Endorphins; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Mice; Morphine Derivatives; Myenteric Plexus; Naloxone; Naltrexone; Organ Specificity; Stereoisomerism; Vas Deferens | 1979 |
3H-Leu5-enkephalin specific binding to synaptic membrane-comparison with 3H-dihydromorphine and 3H-naloxone.
Topics: Animals; Bacitracin; Dihydromorphine; Drug Interactions; Drug Stability; Endorphins; Enkephalins; In Vitro Techniques; Kinetics; Morphine Derivatives; Naloxone; Protein Binding; Rats; Synaptic Membranes; Temperature | 1978 |
Synthesis and binding characteristics of the highly delta-specific new tritiated opioid peptide, [3H]deltorphin II.
Topics: Analgesics; Animals; Benzeneacetamides; Brain; Cell Membrane; Dihydromorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indicators and Reagents; Isotope Labeling; Kinetics; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium | 1992 |
Differential development of beta-endorphin and mu opioid binding sites in mouse brain.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Binding, Competitive; Brain; Dihydromorphine; Embryonic and Fetal Development; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Radioimmunoassay; Receptors, Opioid; Receptors, Opioid, mu | 1992 |
Anterograde transport of opioid receptors in rat vagus nerves and dorsal roots of spinal nerves: pharmacology and sensitivity to sodium and guanine nucleotides.
Topics: Animals; Axonal Transport; Colchicine; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guanosine Triphosphate; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride; Spinal Nerve Roots; Vagus Nerve | 1990 |
Oxymorphone-naltrexonazine, a mixed opiate agonist-antagonist.
Topics: Analgesia; Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; Male; Mice; Mice, Inbred ICR; Naltrexone; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium | 1987 |
Evaluation of delta receptor mediation of supraspinal opioid analgesia by in vivo protection against the beta-funaltrexamine antagonist effect.
Topics: Analgesics, Opioid; Animals; Brain Chemistry; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Injections, Intraventricular; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid; Receptors, Opioid, delta | 1989 |
Computer analysis of the effect of beta-endorphin and dynorphin and related compounds on opioid binding to mouse brain membrane.
Topics: Animals; beta-Endorphin; Binding, Competitive; Brain; Cyclazocine; Dihydromorphine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Mice; Models, Neurological; Receptors, Opioid | 1989 |
Effects of beta-funaltrexamine on radiolabeled opioid binding.
Topics: Animals; Binding, Competitive; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1987 |
Nalbuphine: an autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic.
Topics: Analgesia; Animals; Autoradiography; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Haplorhini; Male; Morphinans; Nalbuphine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1988 |
Monoclonal anti-idiotypic antibodies to opioid receptors.
Topics: Animals; Antibodies, Monoclonal; Antigens; beta-Endorphin; Brain; Cell Membrane; Cyclic AMP; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybridomas; Immunoglobulin G; Immunoglobulin Idiotypes; Immunoglobulin M; Immunosorbent Techniques; Mice; Mice, Inbred BALB C; Naloxone; Rats; Receptors, Opioid; Tumor Cells, Cultured | 1988 |
Relation of diltiazem binding sites to opioid receptor subtypes in the guinea-pig brain.
Topics: Animals; Binding, Competitive; Brain; Cyclazocine; Dihydromorphine; Diltiazem; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Naloxone; Radioligand Assay; Receptors, Opioid | 1987 |
Differential regulation of mu-opiate receptors in heroin- and morphine-dependent rats.
Topics: Animals; Brain; Cell Membrane; Dihydromorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Heroin; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Sodium; Substance-Related Disorders | 1988 |
Characterization of opioid receptor subtypes in solution.
Topics: Animals; Brain; Cations; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Dihydromorphine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Guanylyl Imidodiphosphate; Iodoacetamide; Kinetics; Magnesium; Naloxone; Rats; Receptors, Opioid; Sodium; Solutions | 1986 |
Purification and characterization of the mu opiate receptor from rat brain using affinity chromatography.
Topics: Animals; Brain Chemistry; Cholic Acids; Chromatography, Affinity; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Kinetics; Male; Molecular Weight; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1985 |
Opiate receptor binding profile in the rabbit cerebellum and brain membranes.
Topics: Animals; beta-Endorphin; Binding Sites; Binding, Competitive; Brain; Cerebellum; Cold Temperature; Cyclazocine; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Male; Rabbits; Receptors, Opioid; Sodium; Tritium | 1985 |
Differentiating aspects of opioid receptor binding by [3H](-) (1R,5R,9R,2''S)-5,9-dimethyl-2-tetrahydrofurfuryl-2'-hydroxy-6,7- benzomorphan hydrochloride ([3H]Mr 2034), a drug preferentially acting on kappa-receptors.
Topics: Animals; Benzomorphans; Binding, Competitive; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Kinetics; Male; Morphinans; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
Detection and characterization of four binding sites for opioids in the mouse brain.
Topics: Animals; Binding Sites; Brain Chemistry; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Models, Biological; Naloxone; Receptors, Opioid; Software; Tritium | 1985 |
Opiate binding sites in the chick, rabbit and goldfish retina.
Topics: Animals; Benzomorphans; Chickens; Dihydromorphine; Diprenorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Goldfish; Oligopeptides; Rabbits; Receptors, Opioid; Retina; Species Specificity | 1985 |
Interactions of codeine-7,8-oxide (codeine-epoxide), as a new metabolite of codeine, with multiple opiate receptors.
Topics: Animals; Brain; Cell Membrane; Codeine; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guanosine Triphosphate; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride | 1985 |
Visualization of mu1 opiate receptors in rat brain by using a computerized autoradiographic subtraction technique.
Topics: Animals; Autoradiography; Binding Sites; Brain Chemistry; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Pain; Periaqueductal Gray; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Subtraction Technique; Thalamus | 1985 |
A monoclonal antibody capable of modulating opioid binding to rat neural membranes.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Cyclazocine; Dihydromorphine; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Flunitrazepam; Immunoglobulin M; Kinetics; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Naloxone; Narcotics; Nerve Tissue; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Autoradiographic analysis of mu1, mu2, and delta opioid binding in the central nervous system of C57BL/6BY and CXBK (opioid receptor-deficient) mice.
Topics: Animals; Central Nervous System; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Hybridization, Genetic; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1985 |
Multiple mu opiate receptors: biochemical and pharmacological evidence for multiplicity.
Topics: Animals; Dihydromorphine; Enkephalins; Humans; Morphine; Pain; Receptors, Opioid; Receptors, Opioid, mu | 1986 |
Characterization of opioid receptor binding in adult and fetal sheep brain regions.
Topics: Aging; Animals; Brain Chemistry; Cerebellum; Dihydromorphine; Embryonic and Fetal Development; Enkephalin, Leucine; Female; Frontal Lobe; Hippocampus; Kinetics; Receptors, Opioid; Sheep | 1986 |
Distinct subtypes of the opioid receptor with allosteric interactions in brain membranes.
Topics: Allosteric Site; Animals; Brain; Cations; Cell Membrane; Dihydromorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium | 1986 |
Is there a common, high-affinity opioid binding site in rat brain?
Topics: Animals; Binding, Competitive; Brain Chemistry; Buprenorphine; Dihydromorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Naloxone; Pentazocine; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1986 |
Modulation of rat brain opioid receptors by cannabinoids.
Topics: Animals; Cannabinoids; Cyclazocine; Dihydromorphine; Dose-Response Relationship, Drug; Dronabinol; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Etorphine; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Spiperone | 1987 |
Differential maturation of mu and delta opioid receptors in the chick embryonic brain.
Topics: Animals; Brain; Chick Embryo; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Levorphanol; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
A novel phencyclidine analog interacts selectively with mu opioid receptors.
Topics: Analgesia; Animals; Benzomorphans; Binding, Competitive; Cerebellum; Dihydromorphine; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Muscle Contraction; Naloxone; Phencyclidine; Rats; Receptors, Opioid; Receptors, Opioid, mu; Vas Deferens | 1984 |
Opioid-specific recognition sites of the mu- and the delta-type in rat striatum after lesions with kainic acid.
Topics: Animals; Corpus Striatum; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Kainic Acid; Kinetics; Male; Morphine Derivatives; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1984 |
Effects of ethanol, temperature, and endogenous regulatory factors on the characteristics of striatal opiate receptors.
Topics: Animals; Corpus Striatum; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethanol; Guanosine Triphosphate; Male; Mice; Mice, Inbred C57BL; Receptors, Opioid; Sodium; Temperature | 1984 |
Interaction of morphine-epoxide with multiple opiate receptors.
Topics: Analgesics; Animals; Brain; Dihydromorphine; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Mice; Morphine; Morphine Derivatives; Muscle Contraction; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Neuronal sensitivity to opiate and opioid peptides in the bed nucleus of the stria terminalis. Effects of chronic treatment with morphine.
Topics: Amygdala; Animals; Dihydromorphine; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Evoked Potentials; Guinea Pigs; Hypothalamus, Middle; Male; Morphine; Neural Pathways; Neurons; Norepinephrine; Receptors, Opioid; Synaptic Transmission | 1984 |
Altered opiate receptor binding in synaptosomes: implication of phosphorylation.
Topics: Animals; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Phosphorylation; Receptors, Opioid; Synaptosomes | 1984 |
Binding of beta-carbolines and tetrahydroisoquinolines by opiate receptors of the delta-type.
Topics: Animals; Binding, Competitive; Brain; Carbolines; Dihydromorphine; Enkephalin, Leucine; In Vitro Techniques; Indoles; Isoquinolines; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Synaptosomes | 1984 |
Affinities of some common opioid analgesics towards four binding sites in mouse brain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Binding Sites; Brain; Codeine; Cyclazocine; Dextropropoxyphene; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Methionine; Ethylketocyclazocine; In Vitro Techniques; Membranes; Methadone; Mice; Models, Biological; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1984 |
Characteristics of 3H-tifluadom binding in guinea-pig brain membranes.
Topics: Animals; Benzodiazepines; Benzomorphans; Binding Sites; Brain; Cyclazocine; Dihydromorphine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Male; Morphine; Receptors, Opioid | 1984 |
Guanyl nucleotide interactions with opiate receptors in guinea pig brain and ileum.
Topics: Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Ileum; Kinetics; Male; Morphine Derivatives; Organ Specificity; Receptors, Opioid | 1980 |
Opioid binding properties of brain and peripheral tissues: evidence for heterogeneity in opioid ligand binding sites.
Topics: Adrenal Medulla; Animals; Brain; Cattle; Corpus Striatum; Dihydromorphine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Male; Mice; Organ Specificity; Rabbits; Rats; Receptors, Opioid; Species Specificity; Vas Deferens | 1980 |
Multiple opiate receptors: [3H]ethylketocyclazocine receptor binding and ketocyclazocine analgesia.
Topics: Analgesics; Animals; Brain; Cyclazocine; Dihydromorphine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Mice; Morphine; Motor Activity; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1980 |
Morphiceptin (NH4-tyr-pro-phe-pro-COHN2): a potent and specific agonist for morphine (mu) receptors.
Topics: Animals; Binding, Competitive; Caseins; Dihydromorphine; Endorphins; Enkephalins; Guanosine Triphosphate; Guinea Pigs; Ileum; Male; Mice; Naloxone; Rats; Receptors, Opioid; Sodium; Vas Deferens | 1981 |
Tobacco mosaic virus-enkephalin conjugates: potentiation of opioid activity.
Topics: Animals; Binding, Competitive; Biological Assay; Dihydromorphine; Drug Synergism; Endorphins; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Muscle Contraction; Myenteric Plexus; Receptors, Opioid; Structure-Activity Relationship; Tobacco Mosaic Virus; Vas Deferens | 1981 |
Seasonal variation in the apparent number of binding sites for 3H-opioid agonists and antagonists.
Topics: Animals; Binding Sites; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Kinetics; Male; Mice; Morphinans; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Seasons | 1981 |
Characterization of the kappa-subtype of the opiate receptor in the guinea-pig brain.
Topics: Animals; Benzomorphans; Binding Sites; Binding, Competitive; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Naloxone; Naltrexone; Narcotics; Phenoxybenzamine; Receptors, Opioid | 1981 |
Effect of lithium and sodium ions on opiate- and dopamine-receptor binding.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Dihydromorphine; Enkephalin, Leucine-2-Alanine; Enkephalins; Lithium; Naloxone; Rats; Receptors, Dopamine; Receptors, Opioid; Sodium; Spiperone | 1981 |
Strain differences in opiate receptors in mouse brain.
Topics: Animals; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Naloxone; Receptors, Opioid; Species Specificity | 1981 |
Both mu and delta opiate receptors exist on the same neuron.
Topics: Animals; Dihydromorphine; Electric Conductivity; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Morphine Derivatives; Myenteric Plexus; Neurons; Receptors, Opioid | 1981 |
Dehydro-enkephalins: receptor binding activity of unsaturated analogs of Leu5-enkephalin.
Topics: Animals; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Receptors, Opioid; Structure-Activity Relationship | 1981 |
Opiate receptor-binding activity of [D-Thr2,Thz5]-and [D-Met2,Thz5]-enkephalinamides.
Topics: Animals; beta-Endorphin; Brain Chemistry; Cell Membrane; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalins; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Thiazolidines | 1981 |
A multiplicity of opiate receptors and enkephalin neuronal systems.
Topics: Animals; Binding, Competitive; Brain; Brain Mapping; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Humans; Morphine; Naloxone; Nociceptors; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1982 |
The binding of kappa- and sigma-opiates in rat brain.
Topics: Animals; Binding Sites; Brain; Culture Techniques; Cyclazocine; Dihydromorphine; Enkephalins; Ethylketocyclazocine; Ligands; Male; Naloxone; Narcotics; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Tritium | 1982 |
Reduction of opioid binding in neuroblastoma x glioma cells grown in medium containing unsaturated fatty acids.
Topics: Animals; Cell Line; Dihydromorphine; Enkephalins; Fatty Acids, Unsaturated; Kinetics; Membrane Fluidity; Membrane Lipids; Naloxone; Neurons; Rats; Receptors, Opioid | 1982 |
The opiate receptor-binding interactions of opiate alkaloids and of an opioid peptide in rat brain membranes. Selection by manganese ions and by cholic acid (sodium salt) and minimalization of cross-reaction in vitro.
Topics: Animals; Binding, Competitive; Brain; Cholic Acid; Cholic Acids; Dihydromorphine; Endorphins; Enkephalins; Female; In Vitro Techniques; Male; Manganese; Membranes; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Dehydro-enkephalins. III. Synthesis and biological activity of [delta Ala2, Leu5]-enkephalin.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Methods; Rats; Receptors, Opioid | 1982 |
Naltrexone-induced opiate receptor supersensitivity.
Topics: Animals; Brain; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Female; Guanosine Triphosphate; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Opiate and opioid peptide binding in rat goldfish: further evidence for opiate receptor heterogeneity.
Topics: Animals; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Goldfish; Male; Naloxone; Narcotics; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma | 1982 |
Opiate receptor-mediated inhibition of catecholamine release in primary cultures of bovine adrenal chromaffin cells.
Topics: Acetylcholine; Adrenal Medulla; Animals; beta-Endorphin; Catecholamines; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Cyclazocine; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Phenazocine; Receptors, Opioid | 1982 |
Evidence for multiple "Kappa" binding sites by use of opioid peptides in the guinea-pig lumbo-sacral spinal cord.
Topics: Animals; Binding Sites; Cyclazocine; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Guinea Pigs; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord | 1982 |
The binding to rat brain homogenates of Mr2034, a universal opiate.
Topics: Animals; Benzomorphans; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Male; Morphinans; Naloxone; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
Dynorphin-(1-13): the effect of in vivo treatment on opiate bindings in vitro.
Topics: Animals; Brain; Dihydromorphine; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Membranes; Mice; Mice, Inbred ICR; Peptide Fragments; Receptors, Opioid | 1983 |
Chronic ethanol changes opiate receptor function in rat striatum.
Topics: Animals; Corpus Striatum; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethanol; Etorphine; Male; Rats; Receptors, Opioid | 1984 |
Biochemical characterization of high-affinity 3H-opioid binding. Further evidence for Mu1 sites.
Topics: Animals; Brain; Cell Membrane; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylmaleimide; Kinetics; Male; Morphine; Morphine Derivatives; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Tritium; Trypsin | 1984 |
Characterization and down-regulation of opiate receptors in aggregating fetal rat brain cells.
Topics: Animals; Brain; Cell Aggregation; Cells, Cultured; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Fetus; Molecular Conformation; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Long-term ethanol alters the binding of 3H-opiates to brain membranes.
Topics: Animals; Brain; Cell Membrane; Dihydromorphine; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethanol; Male; Morphine Derivatives; Naloxone; Rats; Rats, Inbred Strains | 1983 |
[A radioreceptor-assay of a methionine-enkephalin-like substance in human CSF (author's transl)].
Topics: Animals; Dihydromorphine; Endorphins; Enkephalins; Humans; Male; Methionine; Naloxone; Radioligand Assay; Rats | 1980 |
The E. coli envY gene encodes a high affinity opioid binding site.
Topics: Animals; Binding Sites; Cloning, Molecular; Dihydromorphine; DNA; DNA, Bacterial; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Escherichia coli; Gene Expression; Genes, Bacterial; L Cells; Mice; Mutation; Protein Biosynthesis; Receptors, Opioid; Transcription, Genetic; Transfection | 1993 |
Presence of the mu3 opiate receptor in endothelial cells. Coupling to nitric oxide production and vasodilation.
Topics: Animals; Aorta; Arteries; Binding, Competitive; Cells, Cultured; Dihydromorphine; Endothelium, Vascular; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Kinetics; Male; Morphine; Muscle, Smooth, Vascular; Narcotics; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Vasodilation | 1995 |
Antiprogestins inhibit the binding of opioids to mu-opioid receptors in nervous membrane preparations.
Topics: Analgesics; Animals; Dihydromorphine; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Gonanes; Hormone Antagonists; Humans; In Vitro Techniques; Male; Membranes; Mice; Mifepristone; Narcotic Antagonists; Narcotics; Nerve Tissue; Nervous System Neoplasms; Neuroblastoma; Progestins; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sodium; Tumor Cells, Cultured | 1996 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |