enkephalin, leucine has been researched along with deltakephalin in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (59.65) | 18.7374 |
| 1990's | 21 (36.84) | 18.2507 |
| 2000's | 2 (3.51) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bourgoin, S; Cesselin, F; Collin, E; Ferhat, L; Hamon, M | 1 |
| Besse, D; Besson, JM; Lombard, MC | 3 |
| Besse, D; Besson, JM; Lombard, MC; Perrot, S | 1 |
| Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mantelet, S | 1 |
| Calenco-Choukroun, G; Daugé, V; Féger, J; Gacel, G; Roques, BP | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Hamon, M; Legrand, JC; Mauborgne, A | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Chantrel, D; Collin, E; Hamon, M; Mauborgne, A; Pohl, M | 1 |
| Gosnell, BA; Krahn, DD; Majchrzak, MJ | 1 |
| Bigeard, A; Delay-Goyet, P; Roques, BP; Zajac, JM | 1 |
| Baumann, NA; Cabon, F; Cupo, A; Ruiz-Gayo, M; Zalc, B | 1 |
| Besse, D; Besson, JM; Lombard, MC; Roques, BP; Zajac, JM | 1 |
| Cesselin, F; Hamon, M; Legrand, JC; Lutz, O; Mauborgne, A | 1 |
| DeLeon-Jones, FA; Fields, JZ; Lee, JM; Ritzmann, RF; Steece, KA | 1 |
| Belleney, J; Fournié-Zaluski, MC; Gacel, G; Maigret, B; Roques, BP | 1 |
| Delay-Goyet, P; Meucci, E; Roques, BP; Zajac, JM | 1 |
| Daugé, V; Roques, BP; Rossignol, P | 2 |
| Gosnell, BA; Majchrzak, MJ | 1 |
| de Witte, P; Heidbreder, C; Roques, BP | 1 |
| Cunningham, FJ; Stansfield, SC | 2 |
| Frey, EA; Jacobson, AE; Rice, KC; Tocque, B | 1 |
| Garbay-Jaureguiberry, C; Jacquemin-Sablon, A; Le Pecq, JB; Rigaudy, P; Roques, BP | 1 |
| Delay-Goyet, P; Gacel, G; Roques, BP; Seguin, C | 1 |
| Doi, M; Ikuma, K; Inoue, M; Ishida, T; Kitamura, K; Nabae, M; Tanaka, M | 1 |
| Cros, J; Francés, B; Meunier, JC; Porthé, G; Verrier, B | 1 |
| Farges, RC; Meunier, JC; Moisand, C; Puget, A | 1 |
| Breuzé, P; Daugé, V; Delay-Goyet, P; Gacel, G; Roques, BP | 1 |
| Beaudet, A; Bochet, P; Garbay-Jaureguiberry, C; Icard-Liepkalns, C; Pasquini, F; Roques, B; Rossier, J | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Delay-Goyet, P; Foucaud, B; Rigaudy, P; Roques, BP; Zajac, JM | 1 |
| Gottlieb, DI; Mattler, JA; Slaughter, MM | 1 |
| Miller, L; Shaw, JS | 1 |
| Blanchard, JC; Böhme, GA; Roques, BP; Stutzmann, JM | 2 |
| Fournie-Zaluski, MC; Glowinski, J; Hamon, M; Petit, F; Roques, BP | 1 |
| Benoist, JM; Gacel, G; Gautron, M; Guilbaud, G; Kayser, V; Roques, B; Zajac, JM | 1 |
| Heyman, JS; Mosberg, HI; Omnaas, JR; Porreca, F; Vaught, JL | 1 |
| Dickenson, AH; Knox, R; Roques, BP; Sullivan, AF; Zajac, JM | 1 |
| Delay-Goyet, P; Roques, BP; Zajac, JM | 1 |
| Agid, Y; Delay-Goyet, P; Javoy-Agid, F; Roques, BP; Zajac, JM | 1 |
| Belleney, J; Fournie-Zaluski, MC; Roques, BP | 1 |
| Burks, TF; Hruby, VJ; Hurst, R; Mosberg, HI; Porreca, F | 1 |
| Dodey, P; Gacel, G; Petit, F; Roques, BP; Rossignol, P; Zajac, JM | 1 |
| Roques, BP; Zajac, JM | 1 |
| Jauzac, P; Polastron, J | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mauborgne, A | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Legrand, JC; Mauborgne, A | 1 |
| Deschamps, JR; Flippen-Anderson, JL; George, C; Houghten, R; Ward, KB | 1 |
| Bourgoin, S; Cesselin, F; Collin, E; Frechilla, D; Hamon, M; Le Bars, D; Pohl, M | 1 |
| Gosnell, BA; Patel, CK | 1 |
| Dupouy, V; Zajac, JM | 1 |
| Lishmanov, IuB; Maslov, LN; Ugdyzhekova, DS | 1 |
| Lishmanov, IuB; Maslov, LN; Rebrova, TIu; Tam, SV | 1 |
| Block, ML; Hong, JS; Liu, Y; Qian, X; Qin, L | 1 |
57 other study(ies) available for enkephalin, leucine and deltakephalin
| Article | Year |
|---|---|
Kappa-opioid receptor stimulation abolishes mu- but not delta-mediated inhibitory control of spinal Met-enkephalin release.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Indoles; Injections, Spinal; Male; Morphinans; Naloxone; Naltrexone; Neurons; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1992 |
Up-regulation of [3H]DAMGO and [3H]DTLET opioid binding sites in laminae I-II of the spinal cord in intact and deafferented morphine-tolerant rats.
Topics: Animals; Autoradiography; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Morphine; Neurons, Afferent; Oligopeptides; Rats; Receptors, Opioid; Spinal Cord; Up-Regulation | 1992 |
Time-related decreases in mu and delta opioid receptors in the superficial dorsal horn of the rat spinal cord following a large unilateral dorsal rhizotomy.
Topics: Afferent Pathways; Animals; Autoradiography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Functional Laterality; Ganglia, Spinal; Kinetics; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Reference Values; Spinal Cord; Spinal Nerve Roots; Time Factors; Tritium | 1992 |
Regulation of opioid binding sites in the superficial dorsal horn of the rat spinal cord following loose ligation of the sciatic nerve: comparison with sciatic nerve section and lumbar dorsal rhizotomy.
Topics: Analgesics; Animals; Autoradiography; Benzeneacetamides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Nerve Degeneration; Neurons, Afferent; Oligopeptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sciatic Nerve; Spinal Cord | 1992 |
Feedback inhibition of met-enkephalin release from the rat spinal cord in vivo.
Topics: Animals; Calcitonin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Feedback; Indoles; Injections, Spinal; Leucine; Male; Morphinans; Naloxone; Naltrexone; Oligopeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan | 1992 |
Opioid delta agonists and endogenous enkephalins induce different emotional reactivity than mu agonists after injection in the rat ventral tegmental area.
Topics: Animals; Anxiety; Emotions; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Exploratory Behavior; Indoles; Injections; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tegmentum Mesencephali | 1991 |
Differential inhibitory/stimulatory modulation of spinal CCK release by mu and delta opioid agonists, and selective blockade of mu-dependent inhibition by kappa receptor stimulation.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cholecystokinin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; In Vitro Techniques; Male; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1991 |
Autoradiographic distribution of mu, delta and kappa opioid binding sites in the superficial dorsal horn, over the rostrocaudal axis of the rat spinal cord.
Topics: Animals; Autoradiography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Kinetics; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Tritium | 1991 |
Opioid control of the release of Met-enkephalin-like material from the rat spinal cord.
Topics: Animals; Cerebrospinal Fluid; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord; Tetrodotoxin | 1991 |
Effects of preferential delta and kappa opioid receptor agonists on the intake of hypotonic saline.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Drinking; Dynorphins; Eating; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Food Preferences; Hypotonic Solutions; Injections, Intraventricular; Male; Oligopeptides; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Taste | 1990 |
Affinity states of rat brain opioid receptors in different tissue preparations.
Topics: Animals; Autoradiography; Binding Sites; Brain; Buffers; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; HEPES; Isotonic Solutions; Kinetics; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tromethamine | 1990 |
Pharmacological and molecular properties of opioid binding sites synthesized in a cell-free translation system.
Topics: Animals; Benzomorphans; Binding, Competitive; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hybridomas; Mice; Molecular Weight; Morphinans; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; RNA, Messenger | 1990 |
Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1990 |
Opposite effects of delta and mu opioid receptor agonists on the in vitro release of substance P-like material from the rat spinal cord.
Topics: Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; In Vitro Techniques; Male; Morphine; Naloxone; Oligopeptides; Potassium; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Substance P; Tetrodotoxin; Veratridine | 1987 |
Differential down-regulation of delta opioid binding sites during physical dependence on methionine enkephalin in the rat.
Topics: Animals; Brain; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Substance-Related Disorders | 1989 |
Delta opioid receptor selectivity induced by conformational constraints in linear enkephalin-related peptides: 1H 400-MHz NMR study and theoretical calculations.
Topics: Amino Acid Sequence; Chemical Phenomena; Chemistry; Dimethyl Sulfoxide; Enkephalin, Leucine; Enkephalins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Protein Binding; Protein Conformation; Receptors, Opioid; Temperature | 1989 |
Binding in vivo of selective mu and delta opioid receptor agonists: opioid receptor occupancy by endogenous enkephalins.
Topics: Animals; Brain; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydroxamic Acids; In Vitro Techniques; Injections; Kinetics; Male; Mice; Morphine; Oligopeptides; Phenylalanine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thiorphan | 1989 |
Blockade of dopamine receptors reverses the behavioral effects of endogenous enkephalins in the Nucleus caudatus but not in the Nucleus accumbens: differential involvement of delta and mu opioid receptors.
Topics: Animals; Apomorphine; Behavior, Animal; Caudate Nucleus; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Microinjections; Motor Activity; Nucleus Accumbens; Oligopeptides; Phenothiazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Septal Nuclei | 1989 |
Centrally administered opioid peptides stimulate saccharin intake in nondeprived rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Food Preferences; Male; Naloxone; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Saccharin; Time Factors | 1989 |
Kelatorphan, a potent enkephalinases inhibitor, and opioid receptor agonists DAGO and DTLET, differentially modulate self-stimulation behaviour depending on the site of administration.
Topics: Animals; Behavior, Animal; Dextroamphetamine; Dipeptides; Electrodes, Implanted; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Injections; Injections, Intraventricular; Male; Neprilysin; Nucleus Accumbens; Oligopeptides; Rats; Rats, Inbred Strains; Self Stimulation | 1989 |
Involvement of opiate receptor subtypes in the modulation of LHRH secretion by the cockerel (Gallus domesticus) mediobasal hypothalamus in vitro.
Topics: Animals; Benzodiazepines; Chickens; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Male; Naloxone; Oligopeptides; Receptors, Opioid | 1987 |
The mu-opioid receptor in the 7315c tumor cell.
Topics: Cell Membrane; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Oligopeptides; Receptors, Opioid; Receptors, Opioid, mu; Tumor Cells, Cultured | 1987 |
Synthesis and binding properties to DNA and to opioid receptors of enkephalin-ellipticinium conjugates.
Topics: Alkaloids; Animals; Brain; Cell Line; DNA; Ellipticines; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Humans; Oligopeptides; Rats; Receptors, Opioid | 1987 |
[3H][D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6 and [D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6(O-tert-butyl). Two new enkephalin analogs with both a good selectivity and a high affinity toward delta-opioid binding sites.
Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Kinetics; Membranes; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1988 |
Conformational characteristics of receptor-selective opioid peptides. 1H n.m.r. and c.d. spectroscopic studies of delta-kephalin and [Val4]morphiceptin.
Topics: Circular Dichroism; Endorphins; Enkephalins; Magnetic Resonance Spectroscopy; Oligopeptides; Protein Conformation; Receptors, Opioid; Solvents; Temperature | 1988 |
The kappa-opioid receptor from human placenta: hydrodynamic characteristics and evidence for its association with a G protein.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Binding, Competitive; Centrifugation, Density Gradient; Chromatography, Gel; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Female; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Microvilli; Oligopeptides; Placenta; Pregnancy; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Sodium Chloride | 1988 |
Opioid receptor types in the brain of the Afghan pika (Ochotona rufescens), a species which is naturally tolerant to morphine.
Topics: Animals; Binding, Competitive; Brain Chemistry; Diprenorphine; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanylyl Imidodiphosphate; Lagomorpha; Membranes; Morphine; Oligopeptides; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium | 1988 |
Development of conformationally constrained linear peptides exhibiting a high affinity and pronounced selectivity for delta opioid receptors.
Topics: Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Mice; Oligopeptides; Protein Conformation; Receptors, Opioid; Receptors, Opioid, delta | 1988 |
Photoaffinity labeling of opioid delta receptors with an iodinated azido-ligand: [125I][D-Thr2,pN3Phe4,Leu5]enkephalyl-Thr6.
Topics: Affinity Labels; Animals; Azides; Brain; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Ligands; Mice; Oligopeptides; Photochemistry; Rats; Receptors, Opioid; Receptors, Opioid, delta | 1988 |
Comparison of the behavioural effects induced by administration in rat nucleus accumbens or nucleus caudatus of selective mu and delta opioid peptides or kelatorphan an inhibitor of enkephalin-degrading-enzymes.
Topics: Animals; Behavior, Animal; Caudate Nucleus; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Motor Activity; Naloxone; Neprilysin; Norepinephrine; Nucleus Accumbens; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1988 |
Involvement of Mu receptors in the opioid-induced increase in the turnover of mouse brain histamine.
Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Histamine; Male; Methylhistamines; Methylhistidines; Mice; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, mu; Tetrodotoxin | 1988 |
Comparative binding properties of linear and cyclic delta-selective enkephalin analogues: [3H]-[D-Thr2, Leu5] enkephalyl-Thr6 and [3H]-[D-Pen2, D-Pen5] enkephalin.
Topics: Animals; Brain; Cell Line; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Guinea Pigs; Isomerism; Kinetics; Neuroblastoma; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1985 |
Opiate binding sites in the chick, rabbit and goldfish retina.
Topics: Animals; Benzomorphans; Chickens; Dihydromorphine; Diprenorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Goldfish; Oligopeptides; Rabbits; Receptors, Opioid; Retina; Species Specificity | 1985 |
Characterisation of the delta-opioid receptor on the hamster vas deferens.
Topics: Animals; Cricetinae; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Mesocricetus; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Vas Deferens | 1985 |
Differential electrographic patterns for specific mu- and delta-opioid peptides in rats.
Topics: Animals; Electroencephalography; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Epilepsy; Male; Morphine; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1986 |
Further evidence for a role of delta-opiate receptors in the presynaptic regulation of newly synthesized dopamine release.
Topics: Animals; Corpus Striatum; Dipeptides; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Nucleus Accumbens; Oligopeptides; Potassium; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Synapses | 1986 |
Differential depressive action of two mu and delta opioid ligands on neuronal responses to noxious stimuli in the thalamic ventrobasal complex of rat.
Topics: Action Potentials; Animals; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hot Temperature; Male; Naloxone; Neurons; Oligopeptides; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thalamus | 1986 |
Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse.
Topics: Analgesia; Anesthesia, Spinal; Animals; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Morphine; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
Effects of selective mu- and delta-opioid peptides on kindled amygdaloid seizures in rats.
Topics: Amygdala; Animals; Anticonvulsants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kindling, Neurologic; Male; Morphine; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
Opioid receptor subtypes in the rat spinal cord: electrophysiological studies with mu- and delta-opioid receptor agonists in the control of nociception.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Oligopeptides; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Synaptic Transmission | 1987 |
Differences of binding characteristics of non-selective opiates towards mu and delta receptor types.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Cerebellum; Cyclazocine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Etorphine; Male; Oligopeptides; Rabbits; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
Regional distribution of mu, delta and kappa opioid receptors in human brains from controls and parkinsonian subjects.
Topics: Aged; Aged, 80 and over; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Humans; Kinetics; Oligopeptides; Parkinson Disease; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1987 |
Attenuation of endogenous opioid peptide inhibition of [Gln8]luteinizing hormone-releasing hormone secretion during sexual maturation in the cockerel.
Topics: Animals; Chickens; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Male; Naloxone; Oligopeptides; Pyrrolidonecarboxylic Acid; Sexual Maturation; Testosterone | 1988 |
Comparison of conformational properties of linear and cyclic delta selective opioid ligands DTLET (Tyr-D X Thr-Gly-Phe-Leu-Thr) and DPLPE (Tyr-c[D X Pen-Gly-Phe-Pen]) by 1H n.m.r. spectroscopy.
Topics: Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Magnetic Resonance Spectroscopy; Models, Molecular; Narcotics; Oligopeptides; Protein Conformation | 1987 |
Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Digestive System Physiological Phenomena; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hot Temperature; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Narcotics; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1984 |
Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr: a new highly potent and fully specific agonist for opiate delta-receptors.
Topics: Animals; Brain; Electric Stimulation; Enkephalins; Guinea Pigs; Ileum; Kinetics; Male; Mathematics; Mice; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Vas Deferens | 1983 |
Differential properties of mu and delta opiate binding sites studied with highly selective ligands.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Male; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1983 |
Different subtypes of opioid receptors have different affinities for G-proteins.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Amino Acid Sequence; Animals; Binding, Competitive; Cerebellum; Colforsin; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guinea Pigs; Humans; Hybrid Cells; Molecular Sequence Data; Morphine; Naloxone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Oligopeptides; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1994 |
Morphine reduces the release of met-enkephalin-like material from the rat spinal cord in vivo by acting at delta opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord | 1994 |
Mu and delta opioid receptors mediate opposite modulations by morphine of the spinal release of cholecystokinin-like material.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cholecystokinin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Morphine; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1994 |
Crystal structure of deltakephalin: a delta-selective opioid peptide with a novel beta-bend-like conformation.
Topics: Crystallography, X-Ray; Enkephalins; Hydrogen Bonding; Least-Squares Analysis; Oligopeptides; Protein Structure, Secondary; Receptors, Opioid, delta; Water | 1994 |
Opioid control of the release of calcitonin gene-related peptide-like material from the rat spinal cord in vivo.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Calcitonin Gene-Related Peptide; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Spinal; Iodine Radioisotopes; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1993 |
Centrally administered mu- and delta-opioid agonists increase operant responding for saccharin.
Topics: Amino Acid Sequence; Analgesics; Animals; Conditioning, Operant; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Male; Molecular Sequence Data; Oligopeptides; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Saccharin | 1993 |
Effects of neuropeptide FF analogs on morphine analgesia in the nucleus raphe dorsalis.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Microinjections; Molecular Sequence Data; Morphine; Neuropeptides; Oligopeptides; Pain Measurement; Pain Threshold; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1995 |
[The use of central administration of the delta1- and delta2-opiate receptor agonists for prevention of the experimental adrenal arrhythmias].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Epinephrine; Injections, Intraventricular; Male; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Vagus Nerve | 1997 |
[The role of mu- and delta-opiate receptors in resistance of the myocardium to free radical damage].
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Myocardial Contraction; Myocardium; Oligopeptides; Oxidative Stress; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu | 2001 |
Microglial NADPH oxidase mediates leucine enkephalin dopaminergic neuroprotection.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Dopamine; Enkephalin, Leucine; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Indicators and Reagents; Lipopolysaccharides; Mice; Microglia; NADPH Oxidases; Neurons; Neuroprotective Agents; Oligopeptides; Pregnancy; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tumor Necrosis Factor-alpha | 2005 |