enkephalin, leucine and colforsin

enkephalin, leucine has been researched along with colforsin in 108 studies

Research

Studies (108)

TimeframeStudies, this research(%)All Research%
pre-199023 (21.30)18.7374
1990's77 (71.30)18.2507
2000's6 (5.56)29.6817
2010's1 (0.93)24.3611
2020's1 (0.93)2.80

Authors

AuthorsStudies
Gintzler, AR; Xu, H2
Eriksson, PS; Hansson, E; Rönnbäck, L2
Heller, PH; Levine, JD; Taiwo, YO1
Childers, SR; Fleming, L; Konkoy, C; Marckel, D; Pacheco, M; Sexton, T; Ward, S1
Bardin, CW; Fujisawa, M; Morris, PL1
Childers, SR; Nijssen, PC; Sexton, T1
Rengel, I; Schulz, R; Sinowatz, F1
Dziedzicka, M; Lasoń, W; Przewłocka, B; Przewłocki, R1
Gnegy, ME; Mangels, LA1
Bishopric, NH; Sato, B; Webster, KA1
Barthel, F; Becquet, D; Boudouresque, F; Giraud, P; Grino, M; Kowalski, C; Loeffler, JP; Renard, M1
Joshi, J; Sabol, SL1
Jessop, JJ; Taplits, MS1
Bleasdale, JE; Denlinger, LC; Fisher, SK; Mostafapour, SP; Thompson, AK1
Duan, DS; Eiger, S; Lameh, J; Sadée, W; Yu, VC1
Johnson, SM; Pillai, NP1
Chu, HM; Comb, MJ; Kobierski, LA; Tan, Y1
Batter, DK; Kessler, JA1
Dave, HP; Joshi, JB1
Mulder, AH; Schoffelmeer, AN; Wierenga, EA1
Höllt, V; Kley, N; Loeffler, JP; Pittius, CW1
Berry-Kravis, E; Dawson, G; Derechin, V; Kazmierczak, BI1
Mihara, S; North, RA; Surprenant, A1
Kew, D; Kilpatrick, DL1
Aizawa, T; Nozawa, A; Yoshikawa, K1
Cox, BM; Puttfarcken, PS1
Gintzler, AR; Smolens, I; Xu, H1
Childers, SR1
Duman, RS; Nestler, EJ; Tallman, JF1
Hogenboom, F; Mulder, AH; Schoffelmeer, AN1
Al Zein, M; Koch, B; Lutz-Bucher, B1
Crain, B; Crain, SM; Peterson, ER1
Sabol, SL; Yoshikawa, K1
Mulder, AH; Putters, J; Schoffelmeer, AN1
Schwartz, JP1
Wilson, SP1
Beinfeld, MC; Eiden, LE; Moskal, JR; Pruss, RM1
Eiden, LE; Pruss, RM; Siegel, RE1
Kirshner, N; Viveros, OH; Wilson, SP1
Eiden, LE; Hook, VY; Pruss, RM1
Eiden, LE; Hotchkiss, AJ1
Eiden, LE; Ruth, JA1
Childers, SR; Dworkin, SI; Kluttz, BW; Vrana, KE1
Ingram, SL; Williams, JT1
Maggi, R; Martini, L; Pimpinelli, F; Piva, F1
Knapp, RJ; Li, X; Malatynska, E; Roeske, WR; Santoro, G; Waite, S; Wang, Y; Yamamura, HI1
Chakrabarti, S; Law, PY; Loh, HH1
Cole, RL; Green, D; Grossbard, SJ; Hyman, SE; Konradi, C; Leveque, JC; Pollack, AE; Senatus, P1
Gabrilovac, J1
Inturrisi, CE; Jenab, S1
McGinty, JF; Simpson, JN1
Hong, JS; Hudson, PM; Suh, HW1
Goc, A; Hong, JS; Jiang, HK; Poisner, A; Stachowiak, EK; Stachowiak, MK1
Jauzac, P; Polastron, J1
Bare, LA; Mansson, E; Yang, D1
Law, PY; Prather, PL; Tsai, AW1
Bell, GI; Kong, H; Raynor, K; Reisine, T; Takeda, J; Yano, H1
Douglass, J; Dubner, R; Gu, J; Iadarola, MJ; Messersmith, DJ1
Brown, GP; Chien, CC; Pasternak, GW; Standifer, KM; Wahlestedt, C1
Boswell, C; Guardiola-Diaz, HM; Seasholtz, AF1
Olianas, MC; Onali, P1
Sun, X1
Bell, GI; Kong, H; Moe, ST; Portoghese, PS; Raynor, K; Reisine, T; Yasuda, K1
Côté, TE; Izenwasser, S; Weems, HB1
Dorow, J; Feller, DJ; Stuart, JF1
Han, JS; Ren, MF; Shun, XJ; Wang, JF; Yang, HF1
Avidor-Reiss, T; Bayewitch, M; Levy, R; Matus-Leibovitch, N; Nevo, I; Vogel, Z1
Hirst, RA; Lambert, DG1
Bacher, B; Höllt, V; Schulz, S; Wang, X1
Dubner, R; Gu, J; Iadarola, MJ; Kim, DJ; Messersmith, DJ1
Hong, JS; Hudson, PM; McMillian, MK; Pennypacker, KR; Sawin, SB; Simmons, KL; Suh, HH; Thai, L; Wu, GC1
George, SR; Kouvelas, A; O'Dowd, BF; Pak, Y; Rasmussen, J; Scheideler, MA1
Chan, RJ; Crabb, DW; Stewart, MJ1
Ha, TS; Kim, YH; Song, DK; Suh, HW; Wie, MB2
Chien, CC; Pasternak, GW; Ryan-Moro, J; Standifer, KM1
Chiu, TT; Wong, YH; Yung, LY1
Blake, AD; Bot, G; Freeman, JC; Reisine, T1
Cai, YC; Cheng, ZJ; Fan, GH; Jiang, LZ; Ma, L; Pei, G1
Altschuld, R; Hohl, C; Lakatta, EG; Pepe, S; Xiao, RP1
Ayukawa, K; Murata, J; Ogasawara, M; Saimi, I1
Blake, AD; Bot, G; Li, S; Reisine, T1
Höllt, V; Koch, T; Kroslak, T; Mayer, P; Raulf, E1
Georgoussi, Z; Merkouris, M; Milligan, G; Mullaney, I1
Bertin, B; Capeyrou, R; Corbani, M; Emorine, LJ; Lepage, JF; Riond, J1
Fukuda, K; Kato, S; Mima, H; Mori, K; Morikawa, H; Shoda, T2
Cheng, ZJ; Ma, L; Pei, G; Wu, YL; Yu, QM1
Campana, G; Di Toro, R; Murari, G; Sciarretta, V; Spampinato, S1
Clark, MJ; Liu, XY; Medzihradsky, F; Remmers, AE1
Eiden, LE; Hahm, SH; Hsu, CM1
Cassel, JA; Daubert, JD; DeHaven, RN; Gong, J; Mansson, E; Strong, JA; Yu, G; Yu, L; Yue, X; Zhang, S1
Allen, RG; Fujimoto, KI; Nelson, CS; Pellegrino, MJ; Sirianni, MJ1
Wang, HL1
Borsook, D; Hyman, SE; Kobierski, LA; Srivastava, S; Wong, AE1
Allouche, S; Hasbi, A; Homburger, V; Jauzac, P; Polastron, J1
Babey, AM; Cavalli, A; Loh, HH1
Behar, O; Borsook, D; Kobierski, LA; Lewis, S; Smirnova, O1
Carrión, AM; Ledo, F; Link, WA; Mellström, B; Naranjo, JR1
Suh, HW; Won, JS1
Campos, D; Carrión, AM; Jiménez-Díaz, L1
Carlson, RR; Dudman, JT; Konradi, C; Macías, W1
Christie, MJ; Hack, SP; Vaughan, CW1
Boda, K; Gintzler, AR; Szücs, M1
Abagyan, A; Funkelstein, L; Hook, V; Mosier, C; Toneff, T; Ziegler, M1
Chang, Y; Guan, D; Huang, R; Huang, W; Qin, K; Shi, W; Tang, F; Tang, Y; Yang, H; Yang, L; Yang, Y; Yashinov, A; Zhao, L; Zhou, H; Zhou, M1

Other Studies

108 other study(ies) available for enkephalin, leucine and colforsin

ArticleYear
Opioid enhancement of evoked [Met5]enkephalin release requires activation of cholinergic receptors: possible involvement of intracellular calcium.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-01, Volume: 89, Issue:5

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Calcimycin; Calcium; Colforsin; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Fentanyl; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Myenteric Plexus; Naloxone; Pyrrolidines; Receptors, Muscarinic; Receptors, Opioid; Sufentanil

1992
Delta and kappa opiate receptors in primary astroglial cultures. Part II: Receptor sets in cultures from various brain regions and interactions with beta-receptor activated cyclic AMP.
    Neurochemical research, 1992, Volume: 17, Issue:6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Animals; Astrocytes; Brain Stem; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Isoproterenol; Morphine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa

1992
Mediation of serotonin hyperalgesia by the cAMP second messenger system.
    Neuroscience, 1992, Volume: 48, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine; Analgesics; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Isomerism; Male; Nociceptors; Pain; Protein Kinase Inhibitors; Pyrrolidines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Rolipram; Second Messenger Systems; Serotonin; Tetrahydronaphthalenes

1992
Opioid and cannabinoid receptor inhibition of adenylyl cyclase in brain.
    Annals of the New York Academy of Sciences, 1992, Jun-28, Volume: 654

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Imidodiphosphate; Analgesics; Animals; Brain; Cannabinoids; Cells, Cultured; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Neurons; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid; RNA, Messenger

1992
A germ cell factor(s) modulates preproenkephalin gene expression in rat Sertoli cells.
    Molecular and cellular endocrinology, 1992, Volume: 84, Issue:1-2

    Topics: Animals; Blotting, Northern; Colforsin; Cyclic AMP; Enkephalins; Follicle Stimulating Hormone; Gene Expression Regulation; In Vitro Techniques; Male; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; RNA, Messenger; Sertoli Cells; Spermatids; Spermatocytes; Time Factors

1992
Opioid-inhibited adenylyl cyclase in rat brain membranes: lack of correlation with high-affinity opioid receptor binding sites.
    Journal of neurochemistry, 1992, Volume: 59, Issue:6

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Cell Membrane; Colforsin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Male; Naloxone; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium; Sodium Chloride; Sodium Fluoride

1992
Opioid-controlled adenylate cyclase in the guinea-pig myenteric plexus is confined to nerve somata.
    European journal of pharmacology, 1992, Dec-01, Volume: 227, Issue:4

    Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Myenteric Plexus; Receptors, Opioid, mu

1992
Differential effects of opioid receptor agonists on nociception and cAMP level in the spinal cord of monoarthritic rats.
    Life sciences, 1992, Volume: 50, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Arthritis; Benzeneacetamides; Colforsin; Cyclic AMP; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanylyl Imidodiphosphate; Injections, Spinal; Male; Morphine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord

1992
Cyclic AMP accumulation alters calmodulin localization in SK-N-SH human neuroblastoma cells.
    Brain research. Molecular brain research, 1992, Volume: 12, Issue:1-3

    Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Alprostadil; Analgesics; Brimonidine Tartrate; Bucladesine; Calcium; Calmodulin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Cytosol; Edetic Acid; Egtazic Acid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Neuroblastoma; Quinoxalines; Tumor Cells, Cultured; Vasoactive Intestinal Peptide

1992
Beta-adrenergic regulation of a myocardial actin gene via a cyclic AMP-independent pathway.
    The Journal of biological chemistry, 1992, Oct-15, Volume: 267, Issue:29

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Animals, Newborn; Blotting, Northern; Bucladesine; Caffeine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Enkephalins; Gene Expression Regulation; Heart; Heart Ventricles; Isoproterenol; Kinetics; Myocardium; Nifedipine; Potassium Chloride; Propranolol; Protein Precursors; Rats; Receptors, Adrenergic, beta; RNA; RNA, Messenger; Ryanodine

1992
Striatal proenkephalin turnover and gene transcription are regulated by cyclic AMP and protein kinase C-related pathways.
    Neuroscience, 1991, Volume: 43, Issue:1

    Topics: Animals; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Enkephalin, Methionine; Enkephalins; Female; Immunohistochemistry; Neural Pathways; Neurons; Nucleic Acid Hybridization; Pregnancy; Protein Kinase C; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection

1991
Proenkephalin gene expression in C6 rat glioma cells: potentiation of cyclic adenosine 3',5'-monophosphate-dependent transcription by glucocorticoids.
    Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:8

    Topics: Animals; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; Colforsin; Cyclic AMP; Dexamethasone; DNA; Drug Synergism; Enkephalins; Gene Expression; Glioma; Plasmids; Protein Precursors; Rats; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1991
In vitro effect of high doses of morphine on Con A induced lymphokine production.
    Advances in experimental medicine and biology, 1991, Volume: 288

    Topics: Animals; beta-Endorphin; Cell Survival; Cells, Cultured; Clone Cells; Colforsin; Concanavalin A; Cyclic AMP; Depression, Chemical; Dinoprostone; Dose-Response Relationship, Drug; Enkephalins; Female; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Protein Biosynthesis; Receptors, Opioid; Spleen; T-Lymphocytes, Helper-Inducer

1991
The aminosteroid U-73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. A role for Gp in receptor compartmentation.
    The Journal of biological chemistry, 1991, Dec-15, Volume: 266, Issue:35

    Topics: Alprostadil; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Estrenes; GTP-Binding Proteins; Humans; Inositol; Kinetics; Neuroblastoma; Oxotremorine; Phosphatidylinositols; Pyrrolidinones; Receptors, Muscarinic; Scopolamine; Type C Phospholipases

1991
Opioids can produce a concentration-dependent naloxone-reversible enhancement of inhibition of evoked enkephalin release.
    NIDA research monograph, 1990, Volume: 105

    Topics: Analgesics; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; In Vitro Techniques; Myenteric Plexus; Naloxone; Narcotics; Parasympatholytics; Sufentanil; Thionucleotides; Virulence Factors, Bordetella

1990
Regulation of cyclic AMP by the mu-opioid receptor in human neuroblastoma SH-SY5Y cells.
    Journal of neurochemistry, 1990, Volume: 55, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Cell Line; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Morphine; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Theophylline; Vasoactive Intestinal Peptide

1990
Hyperpolarization of myenteric neurons by opioids does not involve cyclic adenosine-3',5'-monophosphate.
    Neuroscience, 1990, Volume: 36, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Colforsin; Cyclic AMP; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Guinea Pigs; In Vitro Techniques; Male; Myenteric Plexus; Neurons

1990
cAMP-dependent regulation of proenkephalin by JunD and JunB: positive and negative effects of AP-1 proteins.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Nov-15, Volume: 88, Issue:22

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Colforsin; Cyclic AMP; Enhancer Elements, Genetic; Enkephalins; Gene Expression Regulation; Genes, fos; Glioma; Humans; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Biosynthesis; Protein Kinases; Protein Precursors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reticulocytes; Second Messenger Systems; Transcriptional Activation; Transfection

1991
Region-specific regulation of preproenkephalin mRNA in cultured astrocytes.
    Brain research. Molecular brain research, 1991, Volume: 11, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Blotting, Northern; Brain; Cells, Cultured; Cerebral Cortex; Colforsin; Corpus Striatum; Enkephalins; Hypothalamus; Isoproterenol; Protein Precursors; Rats; RNA; RNA, Messenger

1991
Transactivation of the proenkephalin gene promoter by the Tax1 protein of human T-cell lymphotropic virus type I.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Feb-01, Volume: 89, Issue:3

    Topics: Animals; Colforsin; DNA Mutational Analysis; Enkephalins; Gene Expression Regulation; Gene Products, tax; Human T-lymphotropic virus 1; In Vitro Techniques; Promoter Regions, Genetic; Protein Precursors; Rats; RNA, Messenger; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured

1992
Opiate receptors in neuronal primary cultures.
    Neuropharmacology, 1990, Volume: 29, Issue:9

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Fetus; Morphine; Neurons; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1990
Role of adenylate cyclase in presynaptic alpha 2-adrenoceptor- and mu-opioid receptor-mediated inhibition of [3H]noradrenaline release from rat brain cortex slices.
    Journal of neurochemistry, 1986, Volume: 46, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Bucladesine; Cadmium; Calcimycin; Cerebral Cortex; Clonidine; Colforsin; Cyclic AMP; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Norepinephrine; Phentolamine; Pyrrolidinones; Rats; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, mu; Rolipram

1986
Involvement of ion channels in the induction of proenkephalin A gene expression by nicotine and cAMP in bovine chromaffin cells.
    The Journal of biological chemistry, 1987, Mar-25, Volume: 262, Issue:9

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Glands; Animals; Calcium; Cattle; Cells, Cultured; Chromaffin System; Colforsin; Cyclic AMP; Enkephalins; Gallopamil; Gene Expression Regulation; Ion Channels; Nicotine; Nifedipine; Protein Precursors; RNA, Messenger; Sodium; Tubocurarine; Verapamil

1987
Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20).
    Journal of neurochemistry, 1988, Volume: 50, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Alprostadil; Animals; Brain; Calcimycin; Colforsin; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybrid Cells; Immunoassay; Mice; Nerve Tissue Proteins; Neuroblastoma; Neurotransmitter Agents; Phosphoproteins; Phosphorylation; Protein Kinases; Serotonin; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

1988
Somatostatin increases an inwardly rectifying potassium conductance in guinea-pig submucous plexus neurones.
    The Journal of physiology, 1987, Volume: 390

    Topics: Action Potentials; Animals; Cesium; Colforsin; Enkephalins; Guinea Pigs; In Vitro Techniques; Ion Channels; Naloxone; Neurons; Norepinephrine; Potassium; Rubidium; Somatostatin; Submucous Plexus; Thionucleotides; Time Factors

1987
Expression and regulation of the proenkephalin gene in rat Sertoli cells.
    Molecular endocrinology (Baltimore, Md.), 1989, Volume: 3, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Colforsin; Dihydrotestosterone; Enkephalins; Follicle Stimulating Hormone; Gene Expression Regulation; Male; Protein Precursors; Rats; RNA; Sertoli Cells; Testosterone; Time Factors

1989
Phorbol ester regulates the abundance of enkephalin precursor mRNA but not of amyloid beta-protein precursor mRNA in rat testicular peritubular cells.
    Biochemical and biophysical research communications, 1989, Jun-15, Volume: 161, Issue:2

    Topics: Amyloid; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Enkephalins; Gene Expression Regulation; Male; Protein Precursors; Rats; RNA, Messenger; Testis; Tetradecanoylphorbol Acetate; Time Factors

1989
Morphine-induced desensitization and down-regulation at mu-receptors in 7315C pituitary tumor cells.
    Life sciences, 1989, Volume: 45, Issue:20

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Colforsin; Diprenorphine; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Morphine; Pituitary Neoplasms; Rats; Receptors, Opioid; Receptors, Opioid, mu; Tumor Cells, Cultured

1989
Opioids can enhance and inhibit the electrically evoked release of methionine-enkephalin.
    Brain research, 1989, Dec-11, Volume: 504, Issue:1

    Topics: Action Potentials; Animals; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Myenteric Plexus; Naloxone; Sufentanil

1989
Opiate-inhibited adenylate cyclase in rat brain membranes depleted of Gs-stimulated adenylate cyclase.
    Journal of neurochemistry, 1988, Volume: 50, Issue:2

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Brain; Cell Membrane; Cholera Toxin; Colforsin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Male; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Fluoride; Virulence Factors, Bordetella

1988
Acute and chronic opiate-regulation of adenylate cyclase in brain: specific effects in locus coeruleus.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Locus Coeruleus; Male; Morphine; Narcotics; Neurons; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Time Factors; Virulence Factors, Bordetella

1988
Sodium dependent 3H-noradrenaline release from rat neocortical slices in the absence of extracellular calcium: presynaptic modulation by mu-opioid receptor and adenylate cyclase activation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:5

    Topics: Adenylyl Cyclases; Animals; Calcium; Cerebral Cortex; Colforsin; Desipramine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Extracellular Space; Male; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium; Veratrine

1988
Modulation by Leu-enkephalin of peptide release from perifused neurointermediate pituitary. II. Inhibition of calcium-mediated secretion of alpha-MSH and beta-endorphin.
    Neuroendocrinology, 1986, Volume: 42, Issue:3

    Topics: Animals; beta-Endorphin; Calcimycin; Calcium; Colforsin; Corticotropin-Releasing Hormone; Endorphins; Enkephalin, Leucine; Isoproterenol; Male; Melanocyte-Stimulating Hormones; Pituitary Gland, Posterior; Potassium; Rats; Rats, Inbred Strains; Veratridine

1986
Cyclic AMP or forskolin rapidly attenuates the depressant effects of opioids on sensory-evoked dorsal-horn responses in mouse spinal cord-ganglion explants.
    Brain research, 1986, Apr-02, Volume: 370, Issue:1

    Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ganglia, Spinal; Mice; Morphine; Organ Culture Techniques; Spinal Cord

1986
Glucocorticoids and cyclic AMP synergistically regulate the abundance of preproenkephalin messenger RNA in neuroblastoma-glioma hybrid cells.
    Biochemical and biophysical research communications, 1986, Aug-29, Volume: 139, Issue:1

    Topics: Base Sequence; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enkephalin, Methionine; Enkephalins; Gene Expression Regulation; Glioma; Glucocorticoids; Hybrid Cells; Neuroblastoma; Protein Precursors; RNA, Messenger

1986
Activation of presynaptic alpha 2-adrenoceptors attenuates the inhibitory effect of mu-opioid receptor agonists on noradrenaline release from brain slices.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 333, Issue:4

    Topics: Animals; Brain Chemistry; Cadmium; Clonidine; Colforsin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Morphine; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, mu

1986
Chronic exposure to opiate agonists increases proenkephalin biosynthesis in NG108 cells.
    Brain research, 1988, Volume: 427, Issue:2

    Topics: Animals; Cell Line; Colforsin; Enkephalin, Methionine; Enkephalins; Etorphine; Genes; Glioma; Hybrid Cells; Morphinans; Morphine; Naloxone; Neuroblastoma; Protein Precursors; RNA, Messenger; Transcription, Genetic

1988
Reserpine increases chromaffin cell enkephalin stores without a concomitant decrease in other proenkephalin-derived peptides.
    Journal of neurochemistry, 1987, Volume: 49, Issue:5

    Topics: Adrenal Glands; Animals; Cattle; Chromaffin System; Chromatography, High Pressure Liquid; Colforsin; Enkephalins; Molecular Weight; Peptide Fragments; Protein Precursors; Radioligand Assay; Reserpine; Tetrabenazine; Theophylline

1987
Specific regulation of vasoactive intestinal polypeptide biosynthesis by phorbol ester in bovine chromaffin cells.
    Endocrinology, 1985, Volume: 117, Issue:3

    Topics: Animals; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Peptide Biosynthesis; Peptide PHI; Phorbols; Protein Precursors; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Vasoactive Intestinal Peptide

1985
Multiple populations of neuropeptide-containing cells in cultures of the bovine adrenal medulla.
    Brain research, 1985, Volume: 349, Issue:1-2

    Topics: Adrenal Medulla; Animals; Catecholamines; Cattle; Cells, Cultured; Colforsin; Diterpenes; Enkephalin, Leucine; Enkephalin, Methionine; Fluorescent Antibody Technique; In Vitro Techniques; Nerve Tissue Proteins; Phenylethanolamine N-Methyltransferase; Radioimmunoassay; Vasoactive Intestinal Peptide

1985
Relationship between the regulation of enkephalin-containing peptide and dopamine beta-hydroxylase levels in cultured adrenal chromaffin cells.
    Journal of neurochemistry, 1985, Volume: 45, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Medulla; Animals; Cattle; Cell Fractionation; Cells, Cultured; Chromaffin Granules; Colforsin; Dopamine beta-Hydroxylase; Enkephalins; Insulin; Kinetics; Peptides; Subcellular Fractions; Tetrabenazine; Theophylline

1985
Selective regulation of carboxypeptidase peptide hormone-processing enzyme during enkephalin biosynthesis in cultured bovine adrenomedullary chromaffin cells.
    The Journal of biological chemistry, 1985, May-25, Volume: 260, Issue:10

    Topics: Adrenal Medulla; Animals; Carboxypeptidases; Cattle; Cells, Cultured; Chromaffin Granules; Colforsin; Diterpenes; Enkephalin, Methionine; Enkephalins; Kinetics; Peptides; Reserpine

1985
Cyclic adenosine monophosphate regulates vasoactive intestinal polypeptide and enkephalin biosynthesis in cultured bovine chromaffin cells.
    Neuropeptides, 1983, Volume: 4, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Medulla; Animals; Bucladesine; Cardiotonic Agents; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Enkephalins; Kinetics; Vasoactive Intestinal Peptide

1983
Leucine-enkephalin modulation of catecholamine positive chronotropy in rat atria is receptor-specific and calcium-dependent.
    Neuropeptides, 1984, Volume: 4, Issue:2

    Topics: Animals; Calcium; Catecholamines; Colforsin; Diterpenes; Enkephalin, Leucine; Heart; Heart Rate; Isoproterenol; Male; Naloxone; Norepinephrine; Rats; Receptors, Adrenergic

1984
Effects of morphine on forskolin-stimulated pro-enkephalin mRNA levels in rat striatum: a model for acute and chronic opioid actions in brain.
    Brain research. Molecular brain research, 1995, Volume: 32, Issue:2

    Topics: Analgesics; Animals; Colforsin; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Expression; Male; Models, Molecular; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors

1995
Opioid inhibition of Ih via adenylyl cyclase.
    Neuron, 1994, Volume: 13, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cations; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Electric Conductivity; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ion Channels; Neurons; Nodose Ganglion

1994
Inhibition of luteinizing hormone-releasing hormone secretion by delta-opioid agonists in GT1-1 neuronal cells.
    Endocrinology, 1995, Volume: 136, Issue:11

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alprostadil; Amino Acid Sequence; Cell Line; Colforsin; Culture Media, Conditioned; Dinoprostone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gonadotropin-Releasing Hormone; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Neurons; Pyrrolidines; Receptors, Opioid, delta

1995
Human delta opioid receptor: a stable cell line for functional studies of opioids.
    Neuroreport, 1995, Mar-07, Volume: 6, Issue:4

    Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Naltrexone; Radioligand Assay; Receptors, Opioid, delta; Recombinant Proteins

1995
Neuroblastoma Neuro2A cells stably expressing a cloned mu-opioid receptor: a specific cellular model to study acute and chronic effects of morphine.
    Brain research. Molecular brain research, 1995, Volume: 30, Issue:2

    Topics: Analgesics; Animals; Binding, Competitive; Cell Line; Colforsin; Dose-Response Relationship, Drug; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Mice; Models, Biological; Morphine; Neuroblastoma; Receptors, Opioid, mu; Time Factors

1995
Analysis of the proenkephalin second messenger-inducible enhancer in rat striatal cultures.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Sequence; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enhancer Elements, Genetic; Enkephalins; Fetus; Genes, fos; Molecular Sequence Data; Phosphorylation; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Transcription Factor AP-1

1995
Leu-enkephalin modulates the migration inhibition of mouse splenocytes induced by cAMP-elevating agents.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Migration Inhibition; Cell Movement; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, Leucine; Female; In Vitro Techniques; Mice; Mice, Inbred CBA; Naloxone; Spleen; Theophylline

1993
Proenkephalin gene expression: interaction of glucocorticoid and cAMP regulatory elements.
    Biochemical and biophysical research communications, 1995, May-16, Volume: 210, Issue:2

    Topics: Animals; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Dexamethasone; DNA; Enkephalins; Gene Expression Regulation; Plasmids; Promoter Regions, Genetic; Protein Precursors; Rats; Receptors, Glucocorticoid; Tumor Cells, Cultured

1995
Forskolin induces preproenkephalin and preprodynorphin mRNA in rat striatum as demonstrated by in situ hybridization histochemistry.
    Synapse (New York, N.Y.), 1995, Volume: 19, Issue:3

    Topics: Animals; Colforsin; Corpus Striatum; Dynorphins; Enkephalins; Histocytochemistry; In Situ Hybridization; Injections, Intraventricular; Male; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger

1995
Expression of the proenkephalin A gene and [Met5]-enkephalin secretion induced by arachidonic acid in bovine adrenal medullary chromaffin cells: involvement of second messengers.
    Journal of neurochemistry, 1995, Volume: 64, Issue:2

    Topics: Adrenal Medulla; Animals; Arachidonic Acid; Base Sequence; Calcium Channel Blockers; Calmodulin; Cattle; Cells, Cultured; Chromaffin System; Colforsin; Enkephalin, Methionine; Enkephalins; Gene Expression; Imidazoles; Molecular Probes; Molecular Sequence Data; Protein Kinase C; Protein Precursors; RNA, Messenger; Second Messenger Systems; Sphingosine

1995
Regulation of tyrosine hydroxylase gene expression in depolarized non-transformed bovine adrenal medullary cells: second messenger systems and promoter mechanisms.
    Brain research. Molecular brain research, 1994, Volume: 22, Issue:1-4

    Topics: Adrenal Medulla; Animals; Calmodulin; Cattle; Colforsin; Enkephalins; Gene Expression Regulation, Enzymologic; Membrane Potentials; Phenylethanolamine N-Methyltransferase; Promoter Regions, Genetic; Protein Kinase C; Protein Precursors; RNA, Messenger; Second Messenger Systems; Transcriptional Activation; Tyrosine 3-Monooxygenase; Veratridine

1994
Different subtypes of opioid receptors have different affinities for G-proteins.
    Cellular and molecular biology (Noisy-le-Grand, France), 1994, Volume: 40, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Amino Acid Sequence; Animals; Binding, Competitive; Cerebellum; Colforsin; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guinea Pigs; Humans; Hybrid Cells; Molecular Sequence Data; Morphine; Naloxone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Oligopeptides; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured

1994
Expression of two variants of the human mu opioid receptor mRNA in SK-N-SH cells and human brain.
    FEBS letters, 1994, Nov-07, Volume: 354, Issue:2

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; CHO Cells; Colforsin; Cricetinae; Diprenorphine; DNA, Complementary; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Expression; Genetic Variation; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Opioid, mu; RNA, Messenger; Transfection

1994
Mu and delta opioid receptor desensitization in undifferentiated human neuroblastoma SHSY5Y cells.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Cell Differentiation; Colforsin; Cyclic AMP; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Neuroblastoma; Neurons; Receptors, Opioid, delta; Receptors, Opioid, mu; Sensitivity and Specificity; Signal Transduction; Stimulation, Chemical; Tumor Cells, Cultured

1994
Agonists and antagonists bind to different domains of the cloned kappa opioid receptor.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-16, Volume: 91, Issue:17

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Base Sequence; Benzeneacetamides; Binding Sites; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Colforsin; Cyclic AMP; Enkephalin, Leucine; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Naltrexone; Oligodeoxyribonucleotides; Protein Structure, Secondary; Pyrrolidines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Recombinant Fusion Proteins; Recombinant Proteins; Transfection

1994
Basal and inducible transcriptional activity of an upstream AP-1/CRE element (DYNCRE3) in the prodynorphin promoter.
    Molecular and cellular neurosciences, 1994, Volume: 5, Issue:3

    Topics: Animals; Base Sequence; Colforsin; Cyclic AMP; Enkephalins; Gene Expression Regulation; HeLa Cells; Humans; Molecular Sequence Data; PC12 Cells; Plasmids; Promoter Regions, Genetic; Protein Precursors; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic

1994
Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor.
    Neuron, 1994, Volume: 12, Issue:4

    Topics: Adenylyl Cyclases; Analgesia; Animals; Base Sequence; Binding Sites; Cell Line; Colforsin; DNA, Complementary; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Mice; Molecular Sequence Data; Oligonucleotides, Antisense; Receptors, Opioid, delta; Tritium

1994
The cAMP-responsive element in the corticotropin-releasing hormone gene mediates transcriptional regulation by depolarization.
    The Journal of biological chemistry, 1994, May-20, Volume: 269, Issue:20

    Topics: Animals; Base Sequence; Calcium; Calcium Channels; Calmodulin; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; DNA; Enkephalins; Gene Expression Regulation; Humans; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Insertional; Oligodeoxyribonucleotides; PC12 Cells; Plasmids; Potassium; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Transcription, Genetic; Transfection

1994
Activation of opioid and muscarinic receptors stimulates basal adenylyl cyclase but inhibits Ca2+/calmodulin- and forskolin-stimulated enzyme activities in rat olfactory bulb.
    Journal of neurochemistry, 1994, Volume: 63, Issue:1

    Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Carbachol; Colforsin; Enkephalin, Leucine; Fluorides; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Opioid

1994
[The influence of DPDPE on intracellular free calcium concentration induced by Bt2 cAMP and phorbol ester].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1993, Volume: 15, Issue:3

    Topics: Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil

1993
A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding.
    The Journal of biological chemistry, 1993, Nov-05, Volume: 268, Issue:31

    Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Colforsin; Cyclic AMP; Enkephalins; Guanosine Triphosphate; In Vitro Techniques; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Narcotics; Oligodeoxyribonucleotides; Protein Binding; Receptors, Opioid, delta; Recombinant Proteins; Signal Transduction; Sodium; Structure-Activity Relationship

1993
Naltrexone-induced upregulation of mu opioid receptors on 7315c cell and brain membranes: enhancement of opioid efficacy in inhibiting adenylyl cyclase.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1

    Topics: Adenylyl Cyclases; Animals; Brain; Cell Membrane; Colforsin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Naltrexone; Rats; Receptors, Opioid, mu; Tumor Cells, Cultured; Up-Regulation

1993
Mu-opiate receptor binding and function in HOT and COLD selected lines of mice.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:3

    Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Body Temperature; Brain; Brain Chemistry; Colforsin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethanol; Female; Levorphanol; Male; Mice; Mice, Inbred Strains; Naloxone; Nerve Tissue Proteins; Receptors, Opioid, mu

1993
Suppression by [D-Pen2, D-Pen5]enkephalin on cyclic AMP dependent protein kinase-induced, but not protein kinase C-induced increment of intracellular free calcium in NG108-15 cells.
    Life sciences, 1993, Volume: 52, Issue:19

    Topics: Analgesics; Animals; Bucladesine; Calcium; Calcium Channels; Colforsin; Depression, Chemical; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Hybrid Cells; Intracellular Fluid; Mice; Neuroblastoma; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Opioid, delta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Adenylylcyclase supersensitization in mu-opioid receptor-transfected Chinese hamster ovary cells following chronic opioid treatment.
    The Journal of biological chemistry, 1995, Dec-15, Volume: 270, Issue:50

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Analgesics; Analgesics, Opioid; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Morphine; Naloxone; Pertussis Toxin; Phosphodiesterase Inhibitors; Rats; Receptors, Opioid, mu; Recombinant Proteins; Transfection; Virulence Factors, Bordetella

1995
Do SH-SY5Y human neuroblastoma cells express cannabinoid receptors?
    Biochemical Society transactions, 1995, Volume: 23, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Cannabinoids; Colforsin; Cyclic AMP; Dronabinol; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Neuroblastoma; Potassium; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid; Tumor Cells, Cultured

1995
Induction of proenkephalin gene expression in cultured bovine chromaffin cells is dependent on protein synthesis of AP-1 proteins.
    Journal of neurochemistry, 1996, Volume: 66, Issue:6

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cattle; Cells, Cultured; Chromaffin System; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Enkephalins; Gene Expression Regulation; Genes, Immediate-Early; Genes, Reporter; Kinetics; Molecular Sequence Data; Nuclear Proteins; Oligonucleotides; Peptide Fragments; Phosphorylation; Potassium Chloride; Protein Kinase C; Protein Precursors; Proto-Oncogene Proteins c-fos; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1

1996
c-Jun activation of the DYNCRE3 site in the prodynorphin promoter.
    Brain research. Molecular brain research, 1996, Volume: 40, Issue:1

    Topics: Animals; Base Sequence; Binding Sites; Chloramphenicol O-Acetyltransferase; Colforsin; Consensus Sequence; Cyclic AMP Response Element-Binding Protein; Enkephalins; Genes, Reporter; Molecular Sequence Data; Oligodeoxyribonucleotides; PC12 Cells; Promoter Regions, Genetic; Protein Precursors; Proto-Oncogene Proteins c-jun; Rats; Recombinant Proteins; Transcription Factor AP-1; Transcription, Genetic; Transfection

1996
Dexamethasone and forskolin synergistically increase [Met5]enkephalin accumulation in mixed brain cell cultures.
    Brain research, 1996, Aug-19, Volume: 730, Issue:1-2

    Topics: Animals; Astrocytes; Brain; Cells, Cultured; Colforsin; Dexamethasone; Drug Combinations; Drug Synergism; Enkephalin, Methionine; Enkephalins; Glucocorticoids; Neuroglia; Neurons; Protein Precursors; Rats; Rats, Inbred F344; Receptors, Glucocorticoid; RNA, Messenger

1996
Agonist-induced functional desensitization of the mu-opioid receptor is mediated by loss of membrane receptors rather than uncoupling from G protein.
    Molecular pharmacology, 1996, Volume: 50, Issue:5

    Topics: Analgesics; Animals; Binding Sites; Cell Line; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Kidney; Kinetics; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Sensitivity and Specificity; Stimulation, Chemical; Transfection

1996
Dexamethasone represses phorbol ester-, forskolin-, and calcium-stimulated expression of a preproenkephalin A promoter-chloramphenicol acetyltransferase gene via a receptor-mediated mechanism.
    Brain research. Molecular brain research, 1996, Volume: 42, Issue:1

    Topics: Calcimycin; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Depression, Chemical; Dexamethasone; Enkephalins; Gene Expression Regulation, Enzymologic; Genes, Reporter; Glucocorticoids; Humans; Ionophores; Promoter Regions, Genetic; Protein Precursors; Receptors, Glucocorticoid; Tetradecanoylphorbol Acetate

1996
Molecular mechanisms underlying the regulation of proenkephalin gene expression in cultured spinal cord cells.
    Neuropeptides, 1996, Volume: 30, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dexamethasone; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Mollusk Venoms; Nimodipine; Protein Kinase C; Protein Precursors; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Signal Transduction; Spinal Cord; Tetradecanoylphorbol Acetate

1996
Sigma binding in a human neuroblastoma cell line.
    Neurochemical research, 1996, Volume: 21, Issue:11

    Topics: Adenylyl Cyclases; Analgesics; Analysis of Variance; Animals; Binding, Competitive; Brain; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Haloperidol; Humans; Kinetics; Morphine; Naloxone; Neuroblastoma; Pentazocine; Phosphatidylinositols; Receptors, Opioid; Receptors, sigma; Trypsin; Tumor Cells, Cultured

1996
Inverse agonistic effect of ICI-174,864 on the cloned delta-opioid receptor: role of G protein and adenylyl cyclase activation.
    Molecular pharmacology, 1996, Volume: 50, Issue:6

    Topics: Cell Line; Colforsin; Cyclic AMP; Drug Interactions; Enkephalin, Leucine; Humans; Narcotic Antagonists; Receptors, Opioid, delta

1996
Differential opioid agonist regulation of the mouse mu opioid receptor.
    The Journal of biological chemistry, 1997, Jan-10, Volume: 272, Issue:2

    Topics: Adenylate Cyclase Toxin; Analgesics; Animals; Buprenorphine; Colforsin; Cyclic AMP; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Levorphanol; Methadone; Mice; Morphine; Pertussis Toxin; Receptors, Opioid, mu; Virulence Factors, Bordetella

1997
Functional expression, activation and desensitization of opioid receptor-like receptor ORL1 in neuroblastoma x glioma NG108-15 hybrid cells.
    FEBS letters, 1997, Feb-10, Volume: 403, Issue:1

    Topics: Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; GTP-Binding Proteins; Hybrid Cells; Naltrexone; Narcotic Antagonists; Neuroblastoma; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pertussis Toxin; Receptors, Opioid; Receptors, Opioid, delta; Virulence Factors, Bordetella

1997
'Cross talk' between opioid peptide and adrenergic receptor signaling in isolated rat heart.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Animals; Blood Pressure; Colforsin; Cyclic AMP; Enkephalin, Leucine; Ethanolamines; GTP-Binding Proteins; Heart; Male; Myocardium; Naloxone; Narcotic Antagonists; Norepinephrine; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Opioid, delta; Sarcolemma; Second Messenger Systems; Systole; Thionucleotides; Ventricular Function, Left; Virulence Factors, Bordetella

1997
Differential effect of intestinal neuropeptides on invasion and migration of colon carcinoma cells in vitro.
    Cancer letters, 1997, Jun-03, Volume: 116, Issue:1

    Topics: Adenocarcinoma; Animals; Biocompatible Materials; Calcitonin Gene-Related Peptide; Cell Division; Cell Movement; Colforsin; Collagen; Colonic Neoplasms; Dideoxyadenosine; Dose-Response Relationship, Drug; Drug Combinations; Enkephalins; Laminin; Leucine; Mice; Neoplasm Invasiveness; Neurokinin A; Neuropeptide Y; Neuropeptides; Proteoglycans; Somatostatin; Substance P; Tumor Cells, Cultured; Vasoactive Intestinal Peptide

1997
The regulation of prodynorphin gene expression in cultured spinal cord cells: involvement of second messengers.
    Neuropeptides, 1997, Volume: 31, Issue:2

    Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Embryo, Mammalian; Enkephalins; Kinetics; Neurons; Protein Kinase C; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Spinal Cord; Tetradecanoylphorbol Acetate; Transcription, Genetic

1997
Opioid regulation of the mouse delta-opioid receptor expressed in human embryonic kidney 293 cells.
    Molecular pharmacology, 1997, Volume: 52, Issue:2

    Topics: Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Cell Line; Colforsin; Cyclic AMP; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; GTP-Binding Proteins; Humans; Methadone; Mice; Morphine; Point Mutation; Radioligand Assay; Receptors, Opioid, delta; Signal Transduction; Structure-Activity Relationship

1997
Site mutation in the rat mu-opioid receptor demonstrates the involvement of calcium/calmodulin-dependent protein kinase II in agonist-mediated desensitization.
    Journal of neurochemistry, 1997, Volume: 69, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Humans; Mutagenesis, Site-Directed; Mutation; Oocytes; Rats; Receptors, Opioid, mu; Xenopus laevis

1997
Regulation of spontaneous activity of the delta-opioid receptor: studies of inverse agonism in intact cells.
    Journal of neurochemistry, 1997, Volume: 69, Issue:5

    Topics: Adenine; Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cholera Toxin; Clone Cells; Colforsin; Cyclic AMP; Electrophysiology; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Kinetics; Mice; Naloxone; Narcotic Antagonists; Pertussis Toxin; Rats; Receptors, Opioid, delta; Recombinant Proteins; Transfection; Virulence Factors, Bordetella

1997
Agonist-induced signaling and trafficking of the mu-opioid receptor: role of serine and threonine residues in the third cytoplasmic loop and C-terminal domain.
    FEBS letters, 1997, Sep-29, Volume: 415, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Etorphine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Morphine; Mutagenesis, Site-Directed; Receptors, Opioid, mu; Serine; Signal Transduction; Threonine

1997
Adaptations to chronic agonist exposure of mu-opioid receptor-expressing Chinese hamster ovary cells.
    European journal of pharmacology, 1998, Mar-19, Volume: 345, Issue:2

    Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Receptors, Opioid, mu

1998
Partial agonistic activity of naloxone on the opioid receptors expressed from complementary deoxyribonucleic acids in Chinese hamster ovary cells.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diprenorphine; DNA, Complementary; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP Phosphohydrolases; Naloxone; Receptors, Cell Surface; Receptors, Opioid; Transfection

1998
Selective interference of beta-arrestin 1 with kappa and delta but not mu opioid receptor/G protein coupling.
    The Journal of biological chemistry, 1998, Sep-18, Volume: 273, Issue:38

    Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Analgesics; Arrestins; Benzeneacetamides; beta-Arrestin 1; beta-Arrestins; Cell Line; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Proteins; Sequence Deletion; Transfection

1998
Regulation of delta opioid receptors by delta9-tetrahydrocannabinol in NG108-15 hybrid cells.
    Life sciences, 1998, Volume: 63, Issue:14

    Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Dronabinol; Enkephalin, Leucine; Glioma; Mice; Neuroblastoma; Piperidines; Pyrazoles; Rats; Receptors, Opioid, delta; Rimonabant; RNA, Messenger; Tumor Cells, Cultured

1998
Delta opioid receptor down-regulation is independent of functional G protein yet is dependent on agonist efficacy.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Animals; Colforsin; Cyclic AMP; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Rats; Receptors, Opioid; Tumor Cells, Cultured

1998
PACAP activates calcium influx-dependent and -independent pathways to couple met-enkephalin secretion and biosynthesis in chromaffin cells.
    Journal of molecular neuroscience : MN, 1998, Volume: 11, Issue:1

    Topics: Adrenal Glands; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cattle; Chromaffin Cells; Colforsin; Cyclic AMP; Enkephalin, Methionine; Enkephalins; Gene Expression Regulation; Male; Models, Biological; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium; Protein Precursors; Radioimmunoassay; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide

1998
Endomorphins fully activate a cloned human mu opioid receptor.
    FEBS letters, 1998, Nov-13, Volume: 439, Issue:1-2

    Topics: Analgesics, Opioid; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Humans; Oligopeptides; Oocytes; Potassium Channels; Receptors, Opioid, mu; Recombinant Proteins; Transfection; Xenopus

1998
Cyclic AMP analogs induce synthesis, processing, and secretion of prepro nociceptin/orphanin FQ-derived peptides by NS20Y neuroblastoma cells.
    DNA and cell biology, 1999, Volume: 18, Issue:1

    Topics: Animals; Cell Size; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Mice; Narcotics; Neurites; Neuroblastoma; Neurons; Nociceptin; Opioid Peptides; Peptide Fragments; Radioimmunoassay; Receptors, Opioid, delta; RNA, Messenger; Signal Transduction; Thionucleotides; Time Factors; Tumor Cells, Cultured

1999
A conserved arginine in the distal third intracellular loop of the mu-opioid receptor is required for G protein activation.
    Journal of neurochemistry, 1999, Volume: 72, Issue:3

    Topics: Adenylyl Cyclases; Animals; Arginine; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Humans; Kidney; Ligands; Mutation; Radioligand Assay; Rats; Receptors, Opioid, mu

1999
Cyclic AMP-dependent activation of the proenkephalin gene requires phosphorylation of CREB at serine-133 and a Src-related kinase.
    Journal of neurochemistry, 1999, Volume: 73, Issue:1

    Topics: Animals; Animals, Newborn; Astrocytes; Benzoquinones; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enhancer Elements, Genetic; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation; Lactams, Macrocyclic; Phosphorylation; Phosphoserine; Promoter Regions, Genetic; Protein Precursors; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; src-Family Kinases; Transfection

1999
Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.
    The Biochemical journal, 1999, Aug-15, Volume: 342 ( Pt 1)

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Animals; Azides; Cell Membrane; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoelectric Point; Neuroblastoma; Neurons; Oligodeoxyribonucleotides, Antisense; Oligopeptides; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Tumor Cells, Cultured; Virulence Factors, Bordetella

1999
Altered adenylyl cyclase responsiveness subsequent to point mutations of Asp 128 in the third transmembrane domain of the delta-opioid receptor.
    Neuroscience, 1999, Volume: 93, Issue:3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Substitution; Animals; Aspartic Acid; Binding, Competitive; Chlorocebus aethiops; Codon; Colforsin; COS Cells; Cyclic AMP; Diprenorphine; DNA, Complementary; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Ligands; Mice; Mutagenesis, Site-Directed; Naloxone; Pertussis Toxin; Point Mutation; Protein Binding; Receptors, Opioid, delta; Recombinant Fusion Proteins; Second Messenger Systems; Transfection; Virulence Factors, Bordetella

1999
PhosphoCREB and CREM/ICER: positive and negative regulation of proenkephalin gene expression in the paraventricular nucleus of the hypothalamus.
    Journal of molecular neuroscience : MN, 1999, Volume: 12, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; beta-Galactosidase; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Enkephalins; Escherichia coli; Gene Expression Regulation; Interleukin-1; Kinetics; Lipopolysaccharides; Male; Mice; Mice, Transgenic; Muscimol; Neurons; Paraventricular Hypothalamic Nucleus; Phosphorylation; Protein Precursors; Recombinant Proteins; Repressor Proteins; RNA, Messenger; Transcription, Genetic

1999
DREAM-alphaCREM interaction via leucine-charged domains derepresses downstream regulatory element-dependent transcription.
    Molecular and cellular biology, 2000, Volume: 20, Issue:24

    Topics: Amino Acid Motifs; Amino Acid Sequence; Calcium; Calcium-Binding Proteins; Cell Line; Colforsin; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Enkephalins; Gene Expression Regulation; Genes, Regulator; Genes, Reporter; Humans; Kv Channel-Interacting Proteins; Molecular Sequence Data; Mutation; Neuroblastoma; Phosphorylation; Protein Precursors; Recombinant Proteins; Repressor Proteins; RNA, Messenger; Sequence Alignment; Transfection; Tumor Cells, Cultured

2000
The differential molecular mechanisms underlying proenkephalin mRNA expression induced by forskolin and phorbol-12-myristic-13-acetate in primary cultured astrocytes.
    Brain research. Molecular brain research, 2000, Dec-08, Volume: 84, Issue:1-2

    Topics: Animals; Astrocytes; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP Response Element-Binding Protein; Dexamethasone; DNA; Enkephalins; Phosphorylation; Protein Precursors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Response Elements; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

2000
Ca(2+)-dependent prodynorphin transcriptional derepression in neuroblastoma cells is exerted through DREAM protein activity in a kinase-independent manner.
    Molecular and cellular neurosciences, 2003, Volume: 22, Issue:2

    Topics: Animals; Caffeine; Calcium; Calcium Signaling; Calcium-Binding Proteins; Central Nervous System; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation; Genes, Regulator; Humans; Kv Channel-Interacting Proteins; Mutation; Neuroblastoma; Neurons; Protein Biosynthesis; Protein Precursors; Repressor Proteins; RNA, Messenger; Tumor Cells, Cultured

2003
Striatal proenkephalin gene induction: coordinated regulation by cyclic AMP and calcium pathways.
    Brain research. Molecular brain research, 2003, Jul-23, Volume: 115, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antihypertensive Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Carcinogens; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Drug Interactions; Embryo, Mammalian; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Humans; Isoquinolines; Neurons; Nifedipine; Protein Precursors; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection

2003
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.
    Neuropharmacology, 2003, Volume: 45, Issue:5

    Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Probenecid; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Sulfonamides; Synaptic Transmission; Thioinosine; Time Factors; Uricosuric Agents; Vasodilator Agents; Xanthines

2003
Dual effects of DAMGO [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin and CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2) on adenylyl cyclase activity: implications for mu-opioid receptor Gs coupling.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:1

    Topics: Adenylyl Cyclases; Animals; CHO Cells; Colforsin; Cricetinae; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; GTP-Binding Protein alpha Subunits, Gs; Narcotics; Peptide Fragments; Peptides; Pertussis Toxin; Receptors, Opioid, mu; Signal Transduction; Somatostatin

2004
Beta-amyloid peptides undergo regulated co-secretion with neuropeptide and catecholamine neurotransmitters.
    Peptides, 2013, Volume: 46

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Dopamine; Enkephalins; Epinephrine; Galanin; Ganglionic Stimulants; Humans; Neuroblastoma; Neurons; Neuropeptide Y; Neuropeptides; Neurotransmitter Agents; Nicotine; Norepinephrine; Peptide Fragments; Secretory Vesicles

2013
Selective N-glycan editing on living cell surfaces to probe glycoconjugate function.
    Nature chemical biology, 2020, Volume: 16, Issue:7

    Topics: Animals; Cell Line, Tumor; Cell Membrane; CHO Cells; Colforsin; Cricetulus; Enkephalin, Leucine; Epithelial Cells; Gene Expression; Glycoconjugates; Glycosylation; HEK293 Cells; Humans; Mice; Oligosaccharides; Protein Multimerization; Protein Transport; Receptors, Opioid, delta; Transgenes

2020