enkephalin, leucine has been researched along with captopril in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (64.10) | 18.7374 |
| 1990's | 11 (28.21) | 18.2507 |
| 2000's | 1 (2.56) | 29.6817 |
| 2010's | 1 (2.56) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Buckett, WR | 1 |
| Arregui, A; Emson, PC; Iversen, LL; Lee, CM | 1 |
| Arai, Y; Ghoda, K; Kajita, T; Liu, XF; Matsumiya, T; Ohgiya, N; Oka, T; Taniguchi, T | 1 |
| Ishikawa, K; Martinez, JL; Shibanoki, S; Weinberger, SB | 2 |
| Lantz, I; Nyberg, F; Terenius, L | 1 |
| Ayala, JM; Molineaux, CJ | 1 |
| Gao, Y | 1 |
| Kuno, Y; Oka, T | 1 |
| Aoki, K; Hiranuma, T; Ishii, K; Kajiwara, M; Kuno, Y; Matsumiya, T; Oka, T | 1 |
| Wahl, M | 1 |
| Ishii, S; Satoh, M; Yokosawa, H | 1 |
| Altiere, RJ; Crooks, PA; Gillespie, MN; Krechniak, JW; Olson, JW | 1 |
| Hájek, I; Syková, E; Teisinger, J | 1 |
| Martinez, JL; Walker, RC; Weinberger, SB; Zafuto, CE | 1 |
| Faermark, IF; Shvarts, GIa | 1 |
| Geh, SL; Majewski, H; Nott, MW; Rand, MJ | 1 |
| Gros, C; Llorens-Cortes, C; Schwartz, JC | 1 |
| Aoki, K; Kajiwara, M; Oka, T | 1 |
| Ercan, ZS; Ilhan, M; Türker, RK | 1 |
| Antonaccio, MJ; Greenberg, R; O'Keefe, EH | 1 |
| Ilhan, M; Oktay, S; Onur, R; Türker, RK | 1 |
| Corbett, AD; Kosterlitz, HW; McKnight, AT | 1 |
| Brandt, U; Lentzen, H; Palenker, J | 1 |
| Dowdall, MJ; Turner, AJ | 1 |
| Manwaring, D; Mullane, K | 1 |
| Barnett, A; Berger, J; Billard, W; Chipkin, RE; Iorio, LC | 1 |
| Costa, E; Stine, SM; Yang, HY | 1 |
| Banay-Schwartz, M; Cheng, KP; Hui, KS; Lajtha, A | 1 |
| Laubie, M; Schmitt, H | 1 |
| Harty, GJ; Yaksh, TL | 1 |
| Richter, JP; Snyman, JR; Sommers, DK | 1 |
| Jiang, SS | 1 |
| Kalinskaia, LN; Kononenko, VIa | 1 |
| Bachelard, H; Lessard, A; Pître, M | 1 |
| Akahori, K; Hiranuma, T; Iwao, K; Kanai, M; Kitamura, K; Kobayashi, T; Oka, T; Tamaki, R; Taniguchi, T | 1 |
| Akahori, K; Arai, Y; Jin, XL; Kobayashi, H; Kosaka, K; Oka, T; Yoshikawa, M | 1 |
| Ajimi, J; Ito, K; Ito, M; Kawaguchi, M; Kobayashi, H; Miura, M; Suzuki, T; Takahashi, S; Watanabe, M; Yoshikawa, M | 1 |
| Bagley, EE; Gregoriou, GC; Patel, SD; Winters, BL | 1 |
39 other study(ies) available for enkephalin, leucine and captopril
| Article | Year |
|---|---|
The actions of enkephalins are not modified by the "kininase-II" inhibitor captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Interactions; Electric Stimulation; Endorphins; Enkephalins; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Proline; Reaction Time | 1979 |
Separation of human brain angiotensin-converting enzyme from enkephalin-degrading activity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Endorphins; Enkephalins; Male; Peptidyl-Dipeptidase A; Rats; Teprotide | 1979 |
Effects of the subcutaneous administration of enkephalins on tail-flick response and righting reflex of developing rats.
Topics: Aging; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Female; Glycopeptides; Injections, Subcutaneous; Male; Oligopeptides; Pain; Peptides; Posture; Protease Inhibitors; Rats; Rats, Wistar; Reflex | 1992 |
Further characterization of the in vitro hydrolysis of [Leu]- and [Met]enkephalin in rat plasma: HPLC-ECD measurement of substrate and metabolite concentrations.
Topics: Amino Acids; Aminopeptidases; Animals; Captopril; CD13 Antigens; Chromatography, High Pressure Liquid; Endopeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Hydrolysis; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1991 |
Molecular heterogeneity of angiotensin converting enzyme in human cerebrospinal fluid.
Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chlorides; Chromatography, High Pressure Liquid; Enalapril; Enkephalin, Leucine; Humans; Molecular Sequence Data; Molecular Weight; Neurokinin A; Peptidyl-Dipeptidase A; Radioimmunoassay; Substance P | 1991 |
HPLC-ECD determination of the enzymatic hydrolysis of [leu]- and [met]enkephalin in rat plasma.
Topics: Acetylcholinesterase; Aminopeptidases; Animals; Captopril; CD13 Antigens; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Hydrolysis; In Vitro Techniques; Leucine; Male; Oligopeptides; Rats; Rats, Inbred Strains; Thiorphan; Tyrosine | 1990 |
An inhibitor of endopeptidase-24.15 blocks the degradation of intraventricularly administered dynorphins.
Topics: Animals; Brain; Captopril; Cerebral Ventricles; Choroid Plexus; Dynorphins; Enkephalin, Leucine; Kinetics; Leucine; Male; Metalloendopeptidases; Neprilysin; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains | 1990 |
[Plasma leucine enkephalin and beta-endorphin levels in patients with essential hypertension and the effects of captopril].
Topics: Adult; Aged; beta-Endorphin; Captopril; Enkephalin, Leucine; Female; Humans; Hypertension; Male; Middle Aged | 1990 |
Estimation of relative importance of three enzymes in the inactivation of [Met5]-enkephalin and [Met5]-enkephalin-Arg6 in three isolated preparations by employing the inhibitor specific for each enzyme.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Methionine; Enkephalins; Glycopeptides; Guinea Pigs; Ileum; In Vitro Techniques; Male; Metalloendopeptidases; Mice; Mice, Inbred ICR; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Vas Deferens | 1987 |
Inactivation of [Leu5]-enkephalin in three isolated preparations: relative importance of aminopeptidase, endopeptidase-24.11 and peptidyl dipeptidase A.
Topics: Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Leucine; Glycopeptides; Guinea Pigs; Hydrolysis; Ileum; Kinetics; Male; Metalloendopeptidases; Mice; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Vas Deferens | 1986 |
The effect of peptides on cerebrovascular resistance in cats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cats; Cerebral Arteries; Enkephalins; Morphine; Naloxone; Neurotensin; Peptides; Receptors, Bradykinin; Receptors, Neurotransmitter; Receptors, Opioid; Vascular Resistance | 1985 |
Degradation of dynorphin-(1-13) and dynorphin-(1-17) by the neuroblastoma cell membrane. Evidence for the involvement of a cysteine protease.
Topics: Amino Acids; Captopril; Cell Line; Cysteine Endopeptidases; Dynorphins; Endopeptidases; Enkephalin, Leucine; Ethylmaleimide; Neuroblastoma; Peptide Fragments | 1986 |
Pulmonary metabolism of exogenous enkephalins in isolated perfused rat lungs.
Topics: Aminopeptidases; Animals; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; In Vitro Techniques; Leucine; Lung; Male; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
The effect of opioids and of naloxone on Na+,K+-adenosine triphosphatase activity in frog spinal cord membrane fractions.
Topics: Animals; Captopril; Cell Membrane; Endorphins; Enkephalins; Glycopeptides; Morphine; Naloxone; Rana temporaria; Sodium-Potassium-Exchanging ATPase; Spinal Cord | 1985 |
Characterization of enkephalin degradation in rat plasma.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Leucine; Enkephalins; Kinetics; Leucine; Male; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin | 1986 |
[Influence of captopril on the in vitro and in vivo effects of leu- and met-enkephalins].
Topics: Animals; Captopril; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Enkephalin, Leucine; Enkephalin, Methionine; Female; Guinea Pigs; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Pain; Time Factors | 1987 |
Effect of captopril on blood pressure responses to enkephalins in chloralose-anaesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Captopril; Chloralose; Enkephalins; Heart Rate; Hydralazine; Male; Naloxone; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Study of endogenous Tyr-Gly-Gly, a putative enkephalin metabolite, in mouse brain: validation of a radioimmunoassay, localisation and effects of peptidase inhibitors.
Topics: Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Mice; Microwaves; Nalorphine; Neprilysin; Oligopeptides; Protease Inhibitors; Radioimmunoassay; Thiorphan; Tiopronin | 1985 |
The role of bestatin-sensitive aminopeptidase, angiotensin converting enzyme and thiorphan-sensitive "enkephalinase" in the potency of enkephalins in the guinea-pig ileum.
Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin | 1984 |
Alterations by captopril of pain reactions due to thermal stimulation of the mouse foot: interactions with morphine, naloxone and aprotinin.
Topics: Animals; Aprotinin; Behavior, Animal; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Enkephalins; Female; Hot Temperature; Kinins; Male; Mice; Morphine; Naloxone; Nociceptors; Proline; Prostaglandins; Reaction Time; Time Factors | 1980 |
The effect of captopril and ascorbic acid on nonenzymatic methionine enkephalin inactivation in the guinea-pig ileum.
Topics: Animals; Ascorbic Acid; Captopril; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Proline; Puromycin; Sodium Hypochlorite; Teprotide | 1981 |
Potentiation of the morphine-induced respiratory rate depression by captopril.
Topics: Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Synergism; Enkephalins; Female; Male; Mice; Morphine; Proline; Respiration | 1981 |
Increase in potencies of opioid peptides after peptidase inhibition.
Topics: Animals; beta-Endorphin; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Leucine; Male; Mice; Myenteric Plexus; Protease Inhibitors; Rats; Rats, Inbred Strains; Vas Deferens | 1983 |
Enkephalin degradation by enkephalinergic neuroblastoma cells. Involvement of angiotensin-converting-enzyme.
Topics: Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Cell Membrane; Cells, Cultured; Enkephalin, Leucine; Hydrolysis; Leucine; Mice; Neuroblastoma; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin | 1984 |
The metabolism of neuropeptides. Both phosphoramidon-sensitive and captopril-sensitive metallopeptidases are present in the electric organ of Torpedo marmorata.
Topics: Animals; Captopril; Cell Membrane; Electric Organ; Endopeptidases; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glycopeptides; Hydrolysis; In Vitro Techniques; Metalloendopeptidases; Nerve Tissue Proteins; Oligopeptides; Phenanthrolines; Torpedo | 1984 |
Disappearance of enkephalins in the isolated perfused rat lung.
Topics: Angiotensin I; Angiotensin II; Animals; Biological Assay; Captopril; Colon; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Indomethacin; Lung; Perfusion; Prostaglandins; Rats; Rats, Inbred Strains; Stomach | 1984 |
In vitro and in vivo effects of thiorphan: an inhibitor of enkephalinase A.
Topics: Amino Acids, Sulfur; Aminopeptidases; Analgesics; Animals; Captopril; Drug Synergism; Enkephalins; In Vitro Techniques; Male; Mice; Naloxone; Neprilysin; Protease Inhibitors; Thiorphan; Tiopronin | 1982 |
Inhibition of in situ metabolism of [3H](met5)-enkephalin and potentiation of (met5)-enkephalin analgesia by captopril.
Topics: Animals; Behavior, Animal; Captopril; Corpus Striatum; Drug Synergism; Endorphins; Enkephalin, Methionine; Enkephalins; Proline; Rats | 1980 |
Enkephalin degradation stimulated by captopril.
Topics: Aminopeptidases; Animals; Brain; Captopril; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Enzyme Activation; Hydrogen-Ion Concentration; In Vitro Techniques; Proline; Rats | 1980 |
Indication for central vagal endorphinergic control of heart rate in dogs.
Topics: Analgesia; Animals; Brain; Captopril; Dipeptides; Dogs; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Heart Rate; Male; Oligopeptides; Phenylalanine; Physostigmine; Potassium; Puromycin; Vagus Nerve; Veratridine | 1981 |
Effects of thiorphan on the antinociceptive actions of intrathecal [D-Ala2,Met5] enkephalin.
Topics: Amino Acids, Sulfur; Analgesics; Animals; Captopril; Drug Interactions; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Injections, Spinal; Macaca; Morphine; Neprilysin; Protease Inhibitors; Rats; Species Specificity; Thiorphan; Tiopronin | 1982 |
The influence of captopril and naloxone on the Valsalva manoeuvre and systolic time intervals in healthy volunteers.
Topics: Adult; Blood Pressure; Captopril; Enkephalins; Heart Rate; Humans; Male; Myocardial Contraction; Naloxone; Reference Values; Systole; Valsalva Maneuver | 1994 |
[Changes in regulatory peptides at different stages of essential hypertension and their clinical significance].
Topics: beta-Endorphin; Captopril; Enkephalin, Leucine; Humans; Hypertension; Neuropeptides; Neurotensin; Norepinephrine | 1993 |
[The interaction of the renin-angiotensin and enkephalinergic systems of the brain and hypophysis in normal rats and in experimental pathology of the hypothalamo-hypophyseal-adrenal complex].
Topics: Adrenalectomy; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Brain Chemistry; Captopril; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hypothalamo-Hypophyseal System; Male; Pituitary Gland; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Opioid; Renin-Angiotensin System; Time Factors | 1996 |
Mechanisms of the regional hemodynamic effects of a mu-opioid receptor agonist microinjected into the hypothalamic paraventricular nuclei of conscious unrestrained rats.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Captopril; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hemodynamics; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Phentolamine; Propranolol; Rats; Rats, Inbred WKY; Receptors, Opioid, mu | 1997 |
Effects of three peptidase inhibitors, amastatin, captopril and phosphoramidon, on the hydrolysis of [Met5]-enkephalin-Arg6-Phe7 and other opioid peptides.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Captopril; Enkephalins; Glycopeptides; Guinea Pigs; Hydrolysis; Ileum; Male; Membranes; Opioid Peptides; Peptides; Protease Inhibitors; Visual Cortex | 1998 |
Great increase in antinociceptive potency of [Leu5]enkephalin after peptidase inhibition.
Topics: Animals; Captopril; Drug Synergism; Enkephalin, Leucine; Glycopeptides; Guinea Pigs; Ileum; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Pain; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Vas Deferens | 2008 |
Increase in antinociceptive effect of [leu5]enkephalin after intrathecal administration of mixture of three peptidase inhibitors.
Topics: Analgesics; Animals; Captopril; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Enkephalins; Glycopeptides; Injections, Spinal; Male; Nociceptive Pain; Pain Threshold; Peptides; Protease Inhibitors; Rats; Rats, Wistar | 2013 |
Neprilysin Controls the Synaptic Activity of Neuropeptides in the Intercalated Cells of the Amygdala.
Topics: Amygdala; Animals; Captopril; Electrical Synapses; Enkephalins; Glutamic Acid; Leucine; Male; Neprilysin; Protease Inhibitors; Proteolysis; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiorphan | 2020 |