enkephalin, leucine has been researched along with bicuculline in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (25.00) | 18.7374 |
| 1990's | 23 (63.89) | 18.2507 |
| 2000's | 3 (8.33) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bloom, FE; French, ED; Siggins, GR; Zieglgänsberger, W | 1 |
| Pinnock, RD | 2 |
| Johnson, SW; North, RA | 1 |
| Dunwiddie, TV; Lupica, CR; Proctor, WR | 1 |
| Harrison, NL; Lambert, NA; Teyler, TJ | 1 |
| Dowling, JE; Umino, O | 1 |
| Alberch, J; Arenas, E; Marsal, J | 1 |
| Fujimoto, M; Guidotti, A; Hanbauer, I; Kataoka, Y | 1 |
| Arasteh, K; Trulson, ME | 1 |
| Bespalova, ZhD; Mirzoian, RS; Ragimov, KhS | 1 |
| Labella, FS; Sawynok, J | 1 |
| Masukawa, LM; Prince, DA | 1 |
| Imura, H; Katakami, H; Kato, Y; Matsushita, N; Shimatsu, A | 1 |
| de Jonge, FH; Lopes da Silva, FH; Mollevanger, WJ; Tielen, AM | 1 |
| Duka, T; Herz, A; Wüster, M | 1 |
| Randić, M; Wang, RA | 1 |
| Avoli, M; Barbarosie, MT; Nagao, T | 1 |
| Dubrovina, NI | 1 |
| Cunningham, JR; Neal, MJ; Paterson, SJ | 1 |
| Brusa, L; D'Amore, A; Lorenzini, P; Massotti, M | 1 |
| Mulder, AH; Ronken, E; Schoffelmeer, AN | 1 |
| Brotchie, JM; Crossman, AR; Maneuf, YP; Mitchell, IJ | 1 |
| Fields, HL; Pan, ZZ | 1 |
| Bontempi, B; Sharp, FR | 1 |
| Avoli, M; Lopantsev, V | 1 |
| Brodin, E; Fried, K; Gustafsson, H; Stiller, CO | 1 |
| Budai, D; Fields, HL | 1 |
| Grudt, TJ; Henderson, G | 1 |
| Behbehani, MM; Hall, CW | 1 |
| Chavkin, C; Jin, W | 1 |
| Cooper, AJ; Stanford, IM | 1 |
| Jones, EA; McGinty, JF; Wang, JQ | 1 |
| Johnson, SW; Zheng, F | 1 |
| Brailoiu, GC; Dun, NJ; Ohtubo, Y; Wu, SY | 1 |
| Bowman, BR; Goodchild, AK | 1 |
36 other study(ies) available for enkephalin, leucine and bicuculline
| Article | Year |
|---|---|
Opioid peptides may excite hippocampal pyramidal neurons by inhibiting adjacent inhibitory interneurons.
Topics: Animals; Bicuculline; Endorphins; Enkephalins; Hippocampus; Magnesium; Neurons; Rats | 1979 |
A highly selective kappa-opioid receptor agonist, CI-977, reduces excitatory synaptic potentials in the rat locus coeruleus in vitro.
Topics: Amino Acids; Analgesics; Animals; Benzofurans; Benzomorphans; Bicuculline; Depression, Chemical; Electric Stimulation; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Ligands; Locus Coeruleus; Membrane Potentials; Naloxone; Naltrexone; Picrotoxin; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1992 |
Opioids excite dopamine neurons by hyperpolarization of local interneurons.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Bicuculline; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Male; Membrane Potentials; Mesencephalon; Neurons; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Dissociation of mu and delta opioid receptor-mediated reductions in evoked and spontaneous synaptic inhibition in the rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Axons; Baclofen; Bicuculline; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Synapses | 1992 |
Evidence for mu opiate receptors on inhibitory terminals in area CA1 of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Barium; Bicuculline; Dendrites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Ion Channel Gating; Naloxone; Nerve Endings; Potassium Channels; Quinoxalines; Rats; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Dopamine release from interplexiform cells in the retina: effects of GnRH, FMRFamide, bicuculline, and enkephalin on horizontal cell activity.
Topics: Animals; Bicuculline; Darkness; Dopamine; Drug Interactions; Enkephalins; FMRFamide; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Gonadotropin-Releasing Hormone; Neuropeptides; Neurotransmitter Agents; Perches; Retina; Time Factors | 1991 |
GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Effect of gamma-aminobutyric acidA receptor agonists and antagonists on the release of enkephalin-containing peptides from dog adrenal gland.
Topics: Adrenal Medulla; Analgesics; Animals; Bicuculline; Catecholamines; Dogs; Electric Stimulation; Enkephalins; Female; Isoxazoles; Oxazoles; Receptors, GABA-A; Splanchnic Nerves | 1987 |
Morphine increases the activity of midbrain dopamine neurons in vitro.
Topics: Animals; beta-Endorphin; Bicuculline; Dopamine; Endorphins; Enkephalin, Leucine; In Vitro Techniques; Male; Mesencephalon; Mice; Morphine; Neurons; Substantia Nigra | 1985 |
[Effect of the nitro analog of tetrapeptidamide and morphine on the cerebral blood supply].
Topics: Animals; Bicuculline; Cats; Cerebrovascular Circulation; Enkephalins; Hemodynamics; Morphine; Nitro Compounds; Receptors, GABA-A; Reflex | 1984 |
GABA and baclofen potentiate the K+-evoked release of methionine-enkephalin from rat striatal slices.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Corpus Striatum; Drug Synergism; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Picrotoxin; Potassium; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Enkephalin inhibition of inhibitory input to CA1 and CA3 pyramidal neurons in the hippocampus.
Topics: Animals; Bicuculline; Culture Techniques; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Interneurons; Membrane Potentials; Neural Inhibition; Neurons; Reaction Time; Synapses; Synaptic Transmission | 1982 |
Possible involvement of gamma-aminobutyric acid in growth hormone release induced by a Met5-enkephalin analog in conscious rats.
Topics: Animals; Bicuculline; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalins; gamma-Aminobutyric Acid; Growth Hormone; Hormones; Kinetics; Male; Naloxone; Picrotoxin; Rats; Rats, Inbred Strains | 1981 |
Differential effects of enkephalin within hippocampal areas.
Topics: Animals; Bicuculline; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Hippocampus; In Vitro Techniques; Naloxone; Neurons; Rats | 1981 |
Benzodiazepines modulate striatal enkephalin levels via a GABAergic mechanism.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Corpus Striatum; Diazepam; Endorphins; Enkephalin, Methionine; Enkephalins; Fentanyl; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Radioimmunoassay; Rats | 1980 |
Activation of mu-opioid receptor modulates GABAA receptor-mediated currents in isolated spinal dorsal horn neurons.
Topics: Action Potentials; Amino Acid Sequence; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Sequence Data; Muscimol; Naloxone; Naltrexone; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, mu; Spinal Cord | 1994 |
Control of 4-aminopyridine-induced synchronous activity by adenosine A1 and mu-opioid receptor agonists in adult rat hippocampus.
Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1994 |
Effect of Leu-enkephalin on the memory reactivation produced by blockade of the benzodiazepine/GABA-chloride ionophore receptor complex.
Topics: Analysis of Variance; Animals; Avoidance Learning; Bicuculline; Enkephalin, Leucine; Flumazenil; GABA-A Receptor Antagonists; Male; Memory Disorders; Mice; Mice, Inbred BALB C; Picrotoxin; Receptors, Opioid, delta | 1995 |
Enhancement of retinal acetylcholine release by DAMGO: possibly a direct opioid receptor-mediated excitatory effect.
Topics: Acetylcholine; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Male; Rabbits; Rats; Receptors, Opioid, mu; Retina; Strychnine; Xanthines | 1994 |
Area tempestas modulates the behavioural responses to nociceptive stimuli in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Azocines; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Escape Reaction; Foot; Hot Temperature; Male; Morphine; Naltrexone; Narcotic Antagonists; Olfactory Pathways; Pain; Phenazocine; Pressure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Seizures; Tail | 1993 |
Interacting presynaptic kappa-opioid and GABAA receptors modulate dopamine release from rat striatal synaptosomes.
Topics: Analysis of Variance; Animals; Benzeneacetamides; Bicuculline; Corpus Striatum; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Kinetics; Male; Naltrexone; Narcotics; Oligopeptides; Picrotoxin; Potassium; Pyrrolidines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, kappa; Synaptosomes | 1993 |
On the role of enkephalin cotransmission in the GABAergic striatal efferents to the globus pallidus.
Topics: Animals; Bicuculline; Corpus Striatum; Drug Combinations; Efferent Pathways; Enkephalins; gamma-Aminobutyric Acid; Globus Pallidus; Male; Motor Activity; Naloxone; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Reserpine; Synaptic Transmission | 1994 |
Endogenous opioid-mediated inhibition of putative pain-modulating neurons in rat rostral ventromedial medulla.
Topics: Animals; Bicuculline; Brain Mapping; Enkephalins; Evoked Potentials; Male; Medulla Oblongata; Morphine; Naloxone; Nerve Endings; Neurons; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Reflex | 1996 |
Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area.
Topics: Afferent Pathways; Analgesics, Opioid; Animals; Behavior, Animal; Benzazepines; Bicuculline; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Injections; Injections, Intraperitoneal; Interneurons; Morphine; Motor Activity; Naloxone; Nerve Tissue Proteins; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substantia Nigra; Tegmentum Mesencephali | 1997 |
Participation of GABAA-mediated inhibition in ictallike discharges in the rat entorhinal cortex.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Neurons; Potassium Acetate; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1998 |
Opioid-induced release of neurotensin in the periaqueductal gray matter of freely moving rats.
Topics: Analgesics, Opioid; Animals; Bicuculline; Calcium; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Agonists; GABA Antagonists; Male; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Narcotics; Neurotensin; Periaqueductal Gray; Rats; Rats, Sprague-Dawley | 1997 |
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail | 1998 |
Glycine and GABAA receptor-mediated synaptic transmission in rat substantia gelatinosa: inhibition by mu-opioid and GABAB agonists.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Postsynaptic Potentials; Female; GABA Agents; GABA Antagonists; GABA-B Receptor Agonists; Glycine Agents; In Vitro Techniques; Male; Membrane Potentials; Narcotic Antagonists; Patch-Clamp Techniques; Peptide Fragments; Peptides; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glycine; Receptors, Opioid, mu; Somatostatin; Strychnine; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 1998 |
Synaptic effects of nitric oxide on enkephalinergic, GABAergic, and glutamatergic networks of the rat periaqueductal gray.
Topics: Animals; Bicuculline; Blood Pressure; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Hydroxylamine; Imidazoles; Male; Membrane Potentials; Naloxone; Nerve Net; Neural Inhibition; Nitric Oxide; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Synapses | 1998 |
Mu opioids enhance mossy fiber synaptic transmission indirectly by reducing GABAB receptor activation.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Antagonists; Long-Term Potentiation; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission | 1999 |
Presynaptic mu and delta opioid receptor modulation of GABAA IPSCs in the rat globus pallidus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analgesics, Opioid; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Excitatory Amino Acid Antagonists; GABA Antagonists; Globus Pallidus; In Vitro Techniques; Male; Membrane Potentials; Neostriatum; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission; Tetrodotoxin | 1999 |
Intrastriatal GABA(A) receptor blockade does not alter dopamine D(1)/D(2) receptor interactions in the intact rat striatum.
Topics: Animals; Behavior, Animal; Benzazepines; Bicuculline; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Drug Administration Schedule; Dynorphins; Enkephalins; GABA Antagonists; GABA-A Receptor Antagonists; Gene Expression; In Situ Hybridization; Injections, Subcutaneous; Male; Microinjections; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A; RNA, Messenger; Salicylamides | 2001 |
Dual modulation of gabaergic transmission by metabotropic glutamate receptors in rat ventral tegmental area.
Topics: Anesthetics, Local; Animals; Bicuculline; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrophysiology; Enkephalins; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Leucine; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Neural Conduction; Neural Inhibition; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Ventral Tegmental Area | 2003 |
Effects of endomorphin on substantia gelatinosa neurons in rat spinal cord slices.
Topics: Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Postsynaptic Potentials; Female; Male; Membrane Potentials; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Substantia Gelatinosa; Tetrodotoxin; Time Factors | 2003 |
GABA and enkephalin tonically alter sympathetic outflows in the rat spinal cord.
Topics: Adipose Tissue, Brown; Animals; Bicuculline; Blood Pressure; Body Temperature; Enkephalins; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Heart Rate; Male; Naloxone; Narcotic Antagonists; Protein Precursors; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, delta; Receptors, Opioid, mu; RNA, Messenger; Spinal Cord; Sympathetic Nervous System | 2015 |