enkephalin, leucine has been researched along with beta-endorphin in 523 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 291 (55.64) | 18.7374 |
| 1990's | 171 (32.70) | 18.2507 |
| 2000's | 39 (7.46) | 29.6817 |
| 2010's | 19 (3.63) | 24.3611 |
| 2020's | 3 (0.57) | 2.80 |
| Authors | Studies |
|---|---|
| Okasha, A | 1 |
| Butolin, EG; Danilov, GE | 1 |
| Akami, T; Arakawa, K; Matsumoto, S; Mitsuo, M; Nagase, H; Nakai, I; Nakajima, H; Oka, T; Okamoto, M | 1 |
| Collins, KA; Tseng, LF | 5 |
| Barg, J; Belcheva, MM; Bem, WT; Coscia, CJ; Loh, YP; Rius, RA | 1 |
| Garzón, J; Sánchez-Blázquez, P | 4 |
| Kelly, MJ; Loose, MD; Ronnekleiv, OK | 3 |
| Xu, R | 1 |
| Aloyo, VJ | 1 |
| Tang, RR; Tseng, LF | 1 |
| Cabral, JD; Leedham, JA; Monroe, PJ; Robertson, B; Smith, DJ; Taylor, DA | 1 |
| Armstead, WM; Crofton, JT; Leffler, CW; Mirro, R; Share, L; Zuckerman, SL | 1 |
| Ableitner, A; Schulz, R | 1 |
| Cheng, ZP; Gu, DY; Luo, LG; Tong, GX; Wang, ZX; Zhao, BG | 1 |
| Mathias, CJ; May, CN; Whitehead, CJ | 1 |
| Monger, LS; Olliff, CJ | 1 |
| Filippovich, IuB; Gorlenko, VA; Kolin'ko, SI; Kost, NV; Pshenichkin, SF; Zozulia, AA | 1 |
| Bakich, V; Law, S; McIntosh, CH | 1 |
| Nakamura, H; Suzuki, N; Yoshino, S | 1 |
| Barnard, HC; Bornman, MS; de Wet, EH; Luus, HG; Oosthuizen, JM | 1 |
| Han, JS; Ma, QP; Shi, YS | 1 |
| Holman, RB; Widdowson, PS | 1 |
| Han, JS; Ma, QP | 3 |
| Bridges, RS; Kinsley, CH; Mann, PE | 1 |
| Diehl, J; Kraft, K; Stumpe, KO | 1 |
| Cone, RI; Lameh, J; Sadée, W | 1 |
| Jessop, JJ; Taplits, MS | 1 |
| Fadda, P; Fratta, W; Tortorella, A | 1 |
| Butylin, VIu; Dubitskiĭ, AE; Furmanenko, ED; Kreidich, SA; Shvedenko, PV | 1 |
| Adams, ML; Brase, DA; Dewey, WL; Morris, DL | 1 |
| Armstead, WM; Busija, DW; Desiderio, DM; Leffler, CW; Mirro, R | 1 |
| Olianas, MC; Onali, P | 1 |
| Arakawa, K; De Jong, W; Mulder, AH; Versteeg, DH | 1 |
| Bayon, A; Leon-Olea, M; Piña, AL; Sanchez-Alvarez, M | 1 |
| Casellas, AM; Guardiola, H; Renaud, FL | 1 |
| Hogenboom, F; Mulder, AH; Schoffelmeer, AN; Warden, G | 1 |
| Butler, B; Gunion, MW; Miller, S; Moore, RD; Morley, JE; Rosenthal, MJ; Zib, B | 1 |
| Cohen, Y; Jacquot, C; Orosco, M; Robert, JJ; Rouch, C | 1 |
| Coleman, DL; Powell, AM; Recant, L; Rökaeus, A; Timmers, K; Voyles, NR | 1 |
| Capelli, A; Larocca, LM; Lauriola, L; Maggiano, N; Piantelli, M; Ranelletti, FO; Ricci, R | 1 |
| Carr, DB; Cepeda, MS; Lipkowski, AW; Osgood, PF; Silbert, BS; Szyfelbein, SK | 1 |
| Xie, X | 1 |
| Jin, CB; Rockhold, RW | 1 |
| Ma, QP | 1 |
| Desiderio, DM; Liu, DX; Wood, GW | 1 |
| Glowinski, J; Lévy, M; Trovero, F | 1 |
| Pittman, QJ; Thornhill, JA | 1 |
| Bals-Kubik, R; Herz, A; Shippenberg, TS | 1 |
| Green, IC; Khawaja, XZ; Thorpe, JR; Titheradge, MA | 1 |
| Suh, HH; Tseng, LF | 4 |
| Armstead, WM; Busija, DW; Leffler, CW; Mirro, R | 1 |
| Ikeda, K; Iwasaki, Y; Kinoshita, M; Shiojima, T | 1 |
| Herz, A; Shippenberg, TS; Spanagel, R | 1 |
| Lovegren, ES; Puett, D; Zimniski, SJ | 1 |
| Olley, JE; Scheer, J; Tiong, GK; von Jenner, NM | 1 |
| Nakamura, H; Yoshino, S | 1 |
| Cheng, JG; Xie, XK | 1 |
| Blaustein, JD; Olster, DH | 1 |
| Schoffelmeer, AN; Simon, EJ; Yao, YH | 2 |
| Hinderliter, AL; Maixner, W; Sheps, DS | 1 |
| Gioannini, TL; Hiller, JM; Ofri, D; Roques, BP; Schoffelmeer, AN; Simon, EJ; Yao, YH | 1 |
| Apte, RN; Durum, SK; Oppenheim, JJ | 1 |
| Boon, F; Cain, DP; Corcoran, ME | 1 |
| Gao, Y | 1 |
| Izhar, M; Perk, K; Shemesh, M; Varsano, JS | 1 |
| Macdonald, RL; Werz, MA | 1 |
| Bespalova, ZhD; Il'inskiĭ, OB; Kondrikova, ES; Kozlova, MV; Titov, MI | 1 |
| Ashida, Y; Hata, H; Makino, H; Tonoue, T | 1 |
| Kaliner, MA; Logun, C; Lundgren, J; Shelhamer, JH | 1 |
| Christie, MJ; North, RA; Surprenant, A; Williams, JT | 1 |
| Han, JS; Jiang, NC; Wang, JP; Yu, YX | 1 |
| Kolloch, R; Kraft, K; Stumpe, KO; Theobald, R | 1 |
| Kushlinskiĭ, NE; Puzin, MN; Rushanov, MI; Seleznev, AN | 1 |
| Iyengar, S; Kim, HS; Marien, MR; McHugh, D; Wood, PL | 1 |
| Kelesheva, LF; Kotov, AV; Sudakov, KV | 1 |
| Zoloev, GK | 1 |
| Bhathena, SJ; Michaelis, OE; Recant, L; Timmers, K; Voyles, NR; Wilkins, S | 1 |
| Powell, AM; Recant, L; Timmers, KI; Voyles, NR; Wilkins, SD; Zalenski, CM | 1 |
| Shafer, NP | 1 |
| Costa, E; Mocchetti, I; Ritter, A | 1 |
| Abe, K; Letić-Gavrilović, A; Naruse, S; Niina, M; Shibaike, S | 1 |
| Alvarado, MC; Bennett, EL; Hruby, VJ; Martinez, JL; Patterson, TA; Rosenzweig, MR; Schulteis, G | 1 |
| Bidlack, JM; Selley, DE | 1 |
| Kaiser, ET; Taylor, JW | 1 |
| Iukhananov, RIu; Maĭskiĭ, AI; Rozhanets, VV | 1 |
| Hirooka, Y; Mitsuma, T; Nakada, K; Nogimori, T; Nomura, A | 1 |
| Garzon, J; Landahl, HD; Lee, NM | 1 |
| Huidobro-Toro, JP; Li, CH; Valenzuela, R | 1 |
| Ho, WK; Wen, HL | 1 |
| Cao, XD; Chen, BY; He, XP; Zhu, JM | 1 |
| Brooks, AN; Finnie, AD; Haynes, NB; Lamming, GE; Yang, KP | 1 |
| Ali, SF; Hong, JS; Hudson, PM; Mason, GA; Yoshikawa, K | 1 |
| Donahoe, RM; Falek, A; Madden, JJ; Shafer, DA; Zwemer-Collins, J | 1 |
| Bidlack, JM; O'Malley, WE; Schulz, R | 1 |
| Imai, T; Kamikubo, K; Miura, K; Miura, Y; Miyashita, T; Murase, H; Nakamura, S; Niwa, M; Satoh, T; Tomita, A | 1 |
| Bidlack, JM | 1 |
| Everitt, BJ; Herbert, J; Hughes, AM | 1 |
| Gramsch, C; Herz, A; Kosin, S; Schulz, R | 1 |
| Gioannini, TL; Hiller, JM; Keren, O; Simon, EJ | 1 |
| Burks, TF; Hruby, VJ; Kazmierski, W; Lemcke, PK; Shook, JE; Wire, WS | 1 |
| Barr, E; Leslie, SW | 1 |
| Kosterlitz, HW; Paterson, SJ | 1 |
| Nieber, K; Oehme, P | 1 |
| Mergenhagen, S; Pert, CB; Ruff, MR; Wahl, SM | 1 |
| Imura, H; Inoue, T; Kabayama, Y; Kato, Y; Matsushita, N; Ohta, H; Shimatsu, A; Tojo, K; Yanaihara, N | 1 |
| Herz, A; Millan, MJ | 1 |
| Herz, A; Schiller, PW; Schulz, R; Shearman, GT | 1 |
| Zamir, N | 1 |
| Fujimoto, JM; Higgins, MJ; Hong, JS; Hudson, PM; Tseng, LF | 1 |
| Barchas, JD; Evans, CJ; Lorenz, RG | 1 |
| Bitar, KN; Makhlouf, GM | 1 |
| Bicknell, RJ; Chapman, C; Leng, G | 1 |
| Cook, L; Steinfels, GF | 1 |
| Baile, CA; Della-Fera, MA; McLaughlin, CL | 1 |
| Gosnell, BA; Levine, AS; Morley, JE | 1 |
| Di Marzo, V; Howlett, TA; Marino, G; Morris, HR; Palmisano, A; Tomlin, S | 1 |
| Colpaert, FC; Członkowski, A; Herz, A; Höllt, V; Millan, MH; Millan, MJ; Pilcher, CW | 1 |
| Borson-Chazot, F; Jordan, D; Mornex, R; Veisseire, M | 1 |
| Cheng, CH; Hon, WK; Ng, TB; Su, BX | 1 |
| Petraglia, F; Rivier, C; Vale, W | 1 |
| Acker, GR; Molineaux, C; Orlowski, M | 1 |
| Ding, XZ; Fan, SG; Han, JS | 1 |
| Członkowski, A; Herz, A; Millan, MH; Millan, MJ | 1 |
| Faden, AI; Head, VA; McIntosh, TK | 1 |
| Iyengar, S; Kim, HS; Wood, PL | 1 |
| Chin, YC; Jiao, HY; Liu, JS; Liu, Y | 1 |
| Venn, RF | 1 |
| Moon, TD | 1 |
| Brown, MR; Crum, RL | 1 |
| Arasteh, K; Trulson, ME | 1 |
| Bodnar, RJ; Nilaver, G; Portzline, T | 1 |
| Edelman, NH; Santiago, TV | 1 |
| Bhathena, SJ; Powell, AS; Recant, L; Reiser, S; Smith, JC; Timmers, KI; Voyles, NR | 1 |
| Baratti, CM; Introini, IB; McGaugh, JL | 1 |
| Al Zein, M; Koch, B; Lutz-Bucher, B | 1 |
| Ehrenreich, H; Goebel, FD | 1 |
| Eskay, R; Kunos, G; Mosqueda-Garcia, R; Palkovits, M; Zamir, N | 1 |
| Chavkin, C; Gruol, D; Henriksen, SJ; Siggins, GR | 1 |
| Bodnar, RJ; Romero, MT; Sperber, ES | 1 |
| Fujimoto, JM; King, RC; Tseng, LF | 1 |
| Akil, H; Walker, JM; Watson, SJ; Young, E | 1 |
| Luyendijk, W | 1 |
| Recant, L; Timmers, K; Voyles, NR; Wilkins, S; Zalenski, C | 1 |
| McMillen, IC | 1 |
| Beleslin, D; Krstić, S; Mićić, D; Samardzić, R; Tomić-Beleslin, N | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R | 2 |
| Dias, RD; Izquierdo, I; Netto, CA | 1 |
| Männistö, PT; Rauhala, P; Tuominen, RK | 1 |
| Anderson, JH; Merrill, GA | 1 |
| Brown, MR; Lenz, HJ | 1 |
| Lindberg, I; Panula, P | 1 |
| Clement, JG; Shiloff, JD | 1 |
| Ishihara, N; Kobari, M; Yunoki, K | 1 |
| Cunningham, FJ; Stansfield, SC | 1 |
| Bidlack, JM; Hemmick, LM | 1 |
| Timoshin, SS; Zhdanova, TF | 1 |
| Stojanović, V; Varagić, VM | 1 |
| Huang, S | 1 |
| Chikin, AV; Khamitov, KhS; Poletaev, GI; Urazaev, AKh; Volkov, EM | 1 |
| Kumar, MS; Miczek, KA; Noda, K; Shuster, L; Thompson, ML | 1 |
| Bidlack, JM; Selley, DE; Tyler, CB | 1 |
| Hung, TT; LeMaire, WJ | 1 |
| Li, CH; Suh, HH; Tseng, LF | 1 |
| Bailey, D; Gonzales, L; Metlay, M | 1 |
| Minasian, NV | 1 |
| Koenig, JI; Krulich, L; Moss, RL; Wiesner, JB | 1 |
| Almirez, RG; Gilbeau, PM; Holaday, JW; Smith, CG | 1 |
| Iasnetsov, VV; Kaliuzhnyĭ, LV; Pravdivtsev, VA | 1 |
| Hammonds, RG; Ho, CL; Li, CH | 1 |
| Cetel, NS; Quigley, ME; Reid, RL; Ropert, JF; Yen, SS | 1 |
| Ferrara, P; Hammonds, RG; Li, CH; Westphal, M | 1 |
| Dray, A; Nunan, L; Wire, W | 2 |
| Flemström, G; Jedstedt, G; Nylander, O | 1 |
| Howlett, TA; Rees, LH | 1 |
| Moss, RL; Wiesner, JB | 1 |
| Enginar, N; Hatipoğlu, I; Koyuncuoğlu, H | 1 |
| Appel, NM; Kiritsy-Roy, JA; van Loon, GR | 2 |
| Holtzman, SG; Locke, KW | 2 |
| Przewłocki, R | 1 |
| Agnati, LF; Ferraguti, F; Fuxe, K; Ozini, I; Toffano, G; Zoli, M | 1 |
| Bakalkin, GIa; Pivovarov, AS; Romanenko, OK | 1 |
| Simon, EJ | 1 |
| Gaida, W; Ganten, D; Kraft, K; Lang, RE; Unger, T | 2 |
| Hammonds, RG; Li, CH; Westphal, M | 1 |
| Finch, CE; Morgan, DG; Rogers, J; Shoemaker, WJ | 1 |
| Millns, JL; Pittelkow, MR; Sibley, RK; Wick, MR; Winkelmann, RK | 1 |
| Griffths, EC; McDermott, JR | 1 |
| Couture, R; Cuello, AC; Jarvis, J; Milstein, C; Priestley, JV; Wright, B | 1 |
| Cassell, MD; Gray, TS; Kiss, JZ | 1 |
| Brückner, UB; Ganten, D; Lang, RE | 1 |
| König, A; Pitzel, L | 1 |
| Corti, V; Fantozzi, R; Ledda, F; Mantelli, L | 1 |
| Jewelewicz, R | 1 |
| Cabib, S; Mele, A; Puglisi-Allegra, S | 1 |
| Brusov, OS; Tigranian, RA; Vakulina, OP | 1 |
| Iasnetsov, VV; Motin, VG; Pravdivtsev, VA | 1 |
| Chapman, JD | 1 |
| Beleslin, DB; Mićić, D; Samardzić, R; Terzić, B | 1 |
| Kakidani, H | 1 |
| Babak, OIa; Bondarenko, IP | 1 |
| Ferrara, P; Hammonds, RG; Li, CH | 1 |
| Garzón, J; Herz, A; Schulz, R | 1 |
| Garzón, J; Höllt, V; Lee, NM; Sánchez-Blázquez, P | 1 |
| Besser, GM; Clement-Jones, V; McLoughlin, L; Rees, LH; Tomlin, S; Wen, HL | 1 |
| Kitabgi, P; Monier, S | 1 |
| Doerr-Schott, J; Dubois, MP; Lichte, C | 1 |
| Chang, JK; Jen, MF; Lee, NM; Loh, HH; Tulunay, FC | 2 |
| Hiroto, S; Imura, H; Katakami, H; Kato, Y; Matsushita, N; Shimatsu, A | 2 |
| Blatteis, CM | 1 |
| Day, AR; Freer, RJ; Liao, CS | 1 |
| Höllt, V | 1 |
| Simon, EJ; Smith, JR | 1 |
| Hollander, CS; Moldow, RL | 1 |
| Fumagalli, P; Giagnoni, G; Pavesi, D; Santagostino, A; Torretta, E | 1 |
| Caturay, EM; Huidobro-Toro, JP; Lee, NM; Ling, N; Loh, HH; Way, EL | 1 |
| Rossier, J | 1 |
| Asai, M; Furutani, Y; Hirose, T; Inayama, S; Kakidani, H; Morimoto, Y; Nakanishi, S; Noda, M; Numa, S; Takahashi, H | 1 |
| Fujino, M; Imura, H; Katakami, H; Kato, Y; Matsuo, H; Matsushita, N; Shimatsu, A | 1 |
| Christensson, I; Hökfelt, T; Terenius, L; Vincent, SR | 1 |
| Nyberg, F; Sjölund, B; Terenius, L; Wahlström, A | 1 |
| Cuello, AC | 1 |
| Jessell, T; Suzue, T | 1 |
| Garzón, J; Jen, MF; Lee, NM | 1 |
| Ikeda, Y; Imura, H; Jingami, H; Nakai, Y; Nakao, K; Oki, S; Sakamoto, M; Suda, M; Tanaka, I; Tsukada, T; Yoshimasa, T | 1 |
| Herz, A | 2 |
| Azad, R; Baetge, G; Bloom, FE; Sapin, V; Shoemaker, WJ | 1 |
| Barchas, JD; Cone, RI; Goldstein, A; Weber, E | 1 |
| Lypka, A; Szczudlik, A | 1 |
| Coy, DH; Delarue, C; Jegou, S; Leboulenger, F; Leroux, P; Oliver, C; Tonon, MC; Vaudry, H | 1 |
| Grimm, C; Herz, A; Höllt, V; Seizinger, BR | 1 |
| Chrétien, M; Scherrer, H; Seidah, NG | 1 |
| Basbaum, AI; Fields, HL | 1 |
| Herz, A; Höllt, V; Seizinger, BR | 1 |
| Schechter, NL | 1 |
| Rezvani, A; Way, EL | 1 |
| Blanchard, SG; Chang, KJ; Cuatrecasas, P | 1 |
| Gramsch, C; Herz, A; Höllt, V; Maysinger, D; Seizinger, BR; Tilders, F; Vermes, I | 1 |
| Yaksh, TL | 1 |
| Sweet, WH | 1 |
| McQueen, DS; Ribeiro, JA | 1 |
| Huidobro-Toro, JP; Way, EL | 3 |
| Gay, DD; Lahti, RA | 1 |
| Boissier, JR; Dupont, A; Labrie, F; Mérand, Y; Savard, P | 1 |
| De Wied, D; Verhoef, J; Wiegant, VM | 1 |
| del Río, J; Garzón, J; Naranjo, JR; Sánchez-Franco, F | 1 |
| Janson, VE; Owens, LK; Sastry, BV; Tayeb, OS | 1 |
| Chapouthier, G; Rossier, J | 1 |
| Miura, M; Okada, J | 1 |
| Halász, N; Shepherd, GM | 1 |
| Allen, J; Kay, N; Morley, JE | 1 |
| Hernandez, DE; Luttinger, D; Nemeroff, CB; Prange, AJ | 1 |
| Oshima, I | 1 |
| Chariot, J; Dubrasquet, M; Rozé, C; Vaille, C | 1 |
| Bloom, FE; Hatton, JD; Pittman, QJ | 1 |
| Dalith, M; Keren, O; Sarne, Y; Weissman, BA | 1 |
| Loeber, JG; Opmeer, FA; van Ree, JM | 1 |
| Gramsch, C; Herz, A; Höllt, V; Jerlicz, M; Millan, MJ; Przewłocki, R | 1 |
| Besser, GM; Clement-Jones, V; Linsell, CJ; Mullen, PE; Rees, LH; Shanks, MF | 1 |
| Huidobro, F; Huidobro-Toro, JP | 1 |
| Govoni, S; Yang, HY | 1 |
| French, ED; Siggins, GR | 1 |
| Gähwiler, BH; Herrling, PL | 1 |
| Carrasco, MA; Dias, RD; Elisabetsky, E; Izquierdo, I; Perry, ML; Souza, DO | 1 |
| Bouet, F; Boulain, JC; Faure, G; Fromageot, P; Lecocq, G; Menez, A; Morgat, JL; Tremeau, O | 1 |
| Larsson, LI; Stengaard-Pedersen, K | 2 |
| Lightman, SL; Summers, MC | 1 |
| Rees, LH | 1 |
| Bowcock, SA; Clement-Jones, V; Cooke, ED; Cudworth, AG; Medbak, S; Rees, LH; Wass, JA | 1 |
| Keil, LC; Rosella, LM; Summy-Long, JY | 1 |
| Babichev, VN; Ignatkov, VIa; Mironov, SF | 1 |
| Adler, MW; Cowan, A; Tortella, FC | 1 |
| Appel, NM; Van Loon, GR | 1 |
| Boucher, R; Chan, JS; Chrétien, M; Genest, J; Gutkowska, J; Ikeda, M; Seidah, NG | 1 |
| Clark, WG | 1 |
| Tseng, LF | 1 |
| Edens, NK; Kenney, NJ; McKay, LD; Williams, RH; Woods, SC | 1 |
| Fukushima, M; Furui, T; Kageyama, N; Kuwayama, A; Nakao, K | 1 |
| Besser, GM; Gaillard, RC; Grossman, A; Rees, LH; Smith, R | 1 |
| Besser, GM; Clement-Jones, V; Gaillard, R; Grossman, A; Lowry, PJ; Mallinson, J; Ratter, S; Rees, LH; Smith, R | 1 |
| Koo, A; Li, CH; Wong, TM | 1 |
| Ferrara, P; Li, CH | 1 |
| Cowan, A; Tortella, FC | 1 |
| Havemann, U; Kuschinsky, K | 1 |
| Haarmann, I; Herz, A; Höllt, V; Seizinger, BR | 1 |
| Izquierdo, I; Lucion, AB; Palmini, AL; Rosito, G; Sapper, D | 1 |
| Adames, C; Fearon, Z; Guerrero-Muñoz, F; Way, EL | 1 |
| Dean, DM; Lemaire, S; Livett, BG | 1 |
| Bloom, FE; Henriksen, SJ | 1 |
| Millan, MJ | 1 |
| Beleslin, DB; Krstić, SK; Mićić, D; Samardzić, R | 1 |
| Costa, E; Govoni, S; Harsing, LG; Yang, HY | 1 |
| Bewley, TA; Gráf, L; Li, CH; Nicolas, P | 1 |
| Babichev, VN; Ignatkov, VIa; Mironov, SF; Shvachkin, IuP; Smirnova, AP | 1 |
| Dewey, WL; Fu, TC; Jones, D; Martin, BR; Ohlsson, AE | 1 |
| Rothman, RB; Vaught, JL; Westfall, TC | 1 |
| Ishizuka, Y; Kajiwara, M; Matsumiya, T; Negishi, K; Oka, T; Watanabe, Y | 1 |
| Cork, RC; Crago, BR; Davis, TP; Hameroff, SR; Neuman, C; Scherer, K; Womble, JR | 1 |
| Gráf, L; Hui, KS; Lajtha, A | 1 |
| Gramsch, C; Herz, A; Millan, MH; Millan, MJ; Przewłocki, R | 1 |
| Catapane, EJ; Kream, RM; Stefano, GB | 1 |
| Hill, RC; Roemer, D | 1 |
| Martin, R; Schäfer, M; Voigt, KH | 1 |
| Hatanaka, H; Inoue, N | 1 |
| Blalock, JE; Johnson, HM; Smith, EM; Torres, BA | 1 |
| Bloom, FE; Feldman, JD; Gilman, SC; Milner, RJ; Schwartz, JM | 1 |
| Angwin, P; Barchas, JD | 1 |
| Folkesson, R; Han, JS; Terenius, L; Xie, GX; Zhou, ZF | 1 |
| Barbuti, GM; Baso, R; Borin, G; Cima, L; Giusti, P | 1 |
| Guidotti, A; Saiani, L | 1 |
| Dubois, MP; Girod, C; Trouillas, J | 1 |
| Cheng, SS; Fujimoto, JM; Tseng, LF | 1 |
| Bearden, LJ; Snead, OC | 1 |
| Carrasco, MA; Dias, RD; Izquierdo, I; Perry, ML; Souza, DO; Wofchuk, ST | 1 |
| Ho, KP; Ho, WK; Ng, SC; Tsang, D | 1 |
| de Jong, W; Petty, MA; Sitsen, JM | 1 |
| Kravtsov, GM; Orlov, SN; Riazhskiĭ, GG | 1 |
| Frederickson, RC; Geary, LE | 1 |
| Corbett, AD; Kosterlitz, HW; McKnight, AT | 1 |
| Kandasamy, SB; Williams, BA | 1 |
| Meisenberg, G; Simmons, WH | 1 |
| Lewis, RV; Stern, AS | 1 |
| Egawa, M; Imura, H; Katsumaru, Y; Mochizuki, T; Numa, S; Tobe, A; Yamamoto, Y; Yanaihara, C; Yanaihara, N | 1 |
| Garzón, J; Lee, NM; Sánchez-Blázquez, P | 2 |
| Couri, D; Mousa, S | 2 |
| Bloom, FE | 1 |
| Kameyama, T; Ukai, M | 1 |
| Blum, K | 1 |
| Bloom, FE; Eger, EI; Hosobuchi, Y; Johnson, BH; Way, WL | 1 |
| Gintzler, AR; Goodman, RR; Houghten, RA; Johnson, N; Ling, GS; Nishimura, S; Pasternak, GW; Recht, LD; Spiegel, K | 1 |
| Cork, RC; Crago, BR; Davis, TP; Hameroff, SR; Lerman, JC; Neuman, CP; Watts, KS; Weiss, JL; Womble, JR | 1 |
| Hendren, RW; Hong, JS; Yoshikawa, K | 1 |
| Battenberg, EL; Bloom, FE | 1 |
| Lesch, KP; Neuser, D; Przuntek, H; Stasch, JP | 1 |
| Awoke, S; Bhathena, SJ; Recant, L; Tanenberg, RJ; Voyles, NR | 1 |
| Ho, WK; Wen, HL; Wen, PY | 1 |
| Fujioka, T; Hayashi, Y; Kanaoka, Y; Kangawa, K; Matsunaga, T; Matsuo, H; Nakayama, H | 1 |
| Castellano, C; Csányl, V; Dóka, A; Oliverio, A; Puglisi-Allegra, S | 1 |
| Snead, OC; Stephens, H | 1 |
| De Kloet, ER; Kovács, GL; Szabó, G; Versteeg, DH | 1 |
| Barchas, JD; Chang, JK; Evans, CJ; Weber, E | 1 |
| Hayashi, Y; Kangawa, K; Kitamura, K; Matsuo, H; Minamino, N | 1 |
| Chino, N; Kangawa, K; Matsuo, H; Minamino, N; Sakakibara, S | 1 |
| Becklin, RR; Desiderio, DM; Lee, HG; Tseng, JL | 1 |
| Berry, M; Chatikhine, VA; Chevallier, B; Chevrier, A; Delpech, B; Francois, A; Ren, GS | 1 |
| Brenner, S; Han, H; Janda, KD; Wolfe, MM | 1 |
| Choi, YS; Kim, YH; Sim, YB; Song, DK; Suh, HW | 1 |
| Carr, JA; Gregg, KJ | 1 |
| Donahoe, RM; Ketelsen, D; Madden, JJ; Oleson, D; Whaley, WL | 1 |
| Ableitner, A; Hassan, AH; Herz, A; Stein, C | 1 |
| Basile, AS; Ha, JH; Jones, EA; Li, Y; Rothman, R; Yurdaydin, C | 1 |
| Castro, MA; Garzon, J; Juarros, JL; Sanchez-Blazquez, P | 2 |
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| Crain, SM; Shen, KF | 1 |
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| Kim, YH; Song, DK; Suh, HW; Tseng, LF; Yoo, JS | 1 |
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| Constantopoulos, A; Papaconstantinou, E; Papadaki-Papandreou, U | 1 |
| Capasso, A; Di Giannuario, A; Domenici, MR; Loizzo, A; Pieretti, S; Sagratella, S; Sorrentino, L | 1 |
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| Callahan, P; Janik, J; Kehoe, L; Parman, R | 1 |
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| Desiderio, DM; Dohan, FC; Robertson, JT; Sacks, HS; Tseng, JL; Zhu, X | 1 |
| Choi, YS; Kim, YH; Song, DK; Suh, HW | 1 |
| Ding, H; Wang, C; Zhang, T; Zheng, X | 1 |
| Kelly, MJ; Lagrange, AH; Rønnekleiv, OK; Zhang, G | 1 |
| Aebischer, I; Horn, M; Miescher, S; Stadler, BM; Stämpfli, MR; Zürcher, AW | 1 |
| Aromataris, EC; Riederer, BM; Steele, PA | 1 |
| Cui, Y; Lee, TF; Wang, LC | 1 |
| Han, H; Janda, KD | 1 |
| Asea, A; Hellstrand, K; Hoffmann, P; Johansson, C; Jonsdottir, IH; Thorén, P | 1 |
| Diaz, A; Laorden, ML; Milanés, MV; Pazos, A; Sanchez, MD | 1 |
| Kubo, K; Sasaki, T; Torii, M | 2 |
| Bianchi, M; Panerai, AE; Sacerdote, P | 1 |
| Audet, RM; Butterworth, RF; de Waele, JP; Leong, DK | 1 |
| Eriksson, B; Maixner, B; Sheps, DS; Sylvén, C | 1 |
| Choi, SR; Kim, YH; Lee, KJ; Song, DK; Suh, HW | 1 |
| Choi, SR; Chung, KM; Kim, YH; Song, DK; Suh, HW | 1 |
| Chen, SF; Ghanta, VK; Hiramoto, RN; Hsueh, CM; Huang, HJ | 1 |
| Kamei, J; Mizoguchi, H; Narita, M; Ohsawa, M; Tseng, LF | 1 |
| Breivogel, CS; Childers, SR; Nestler, EJ; Selley, DE | 1 |
| Choi, YS; Kim, YH; Song, DK; Suh, HW; Tseng, LF; Yoo, JS | 1 |
| Berkmiller, G; Falk, W; Frauenholz, T; Herrmann, M; Lang, B; Schölmerich, J; Straub, RH | 1 |
| Khan, S; Smith, ME | 1 |
| Kampine, JP; Mizoguchi, H; Narita, M; Tseng, LF | 1 |
| Choi, SR; Huh, SO; Kim, YH; Song, DK; Suh, HW | 1 |
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| Grandy, DK; Kelly, MJ; Rønnekleiv, OK; Wagner, EJ | 1 |
| Andersson, B; Augustinsson, LE; Bergh, CH; Eliasson, T; Hedner, T; Larson, G; Mannheimer, C; Waagstein, F | 1 |
| Ensor, DM; Miles, JB; Morley, JS; Owen, DL | 1 |
| Akil, H; Alt, A; Mansour, A; Medzihradsky, F; Traynor, JR; Woods, JH | 1 |
| Osumi, Y; Yokotani, K | 1 |
| Barron, S; Belcheva, MM; Bohn, LM; Coscia, CJ; Ho, MT; Johnson, FE; Yanai, J | 1 |
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| Celik, T; Karavelioglu, D; Onaran, O; Uzunalimoglu, O; Yaşa, MH; Yurdaydin, C | 1 |
| Chen, J; Liang, R; Lu, D; Yang, W; Zhou, Y | 1 |
| Smith, O | 1 |
| Condamine, E; Costentin, J; Davoust, D; Leprince, J; Mayer, C; Suaudeau, C; Vaudry, H | 1 |
| Chien, GL; Takasaki, Y; van Winkle, DM; Wolff, RA | 1 |
| Billington, CJ; Grace, MK; Kim, EM; Levine, AS; O'Hare, E; Welch, CC | 1 |
| Fulford, AJ; Harbuz, MS; Jessop, DS | 1 |
| Jiang, CL; Liu, XY; Lu, CL; Wang, YX; Xu, D; You, ZD | 1 |
| Huh, SO; Kim, YH; Song, DK; Suh, HW | 1 |
| Gyires, K; Rónai, AZ | 1 |
| Hung, K; Mizoguchi, H; Ohsawa, M; Tseng, LF; Wu, H | 1 |
| Asai, T; Kaneko, A; Sakane, T; Suzuki, N; Takeba, Y | 1 |
| Höllt, V; Mayer, P | 1 |
| Chui, RY; Huang, AJ; Jiang, CL; Liu, XY; Lu, CL; Shao, XY; Song, LX; Wang, YX; You, ZD | 1 |
| Chen, CH; Wu, GC; Xu, SF; Yu, CX | 1 |
| Hayward, MD; Low, MJ; Pintar, JE | 1 |
| Iniushkin, AN | 1 |
| Hong, X; Lin, B; Wang, C; Zhao, X | 1 |
| Cao, L; Gu, H; Hong, X; Hu, D; Jin, Z; Li, P; Liu, Y | 1 |
| Bogacka, I; Kaminski, T; Okrasa, S; Przala, J; Siawrys, G | 1 |
| Appleyard, SM; Hayward, MD; Low, MJ; Rubinstein, M | 1 |
| Dai, SM; Fang, F; Shan, ZZ; Su, DF | 1 |
| Naito, A; Nishimura, K | 1 |
| Bertacchi, I; Gambarelli, A; Mola, L; Pederzoli, A | 1 |
| Fujimoto, JM; Leitermann, RJ; Sun, HS; Thompson, J; Tseng, LF; Wu, HE | 1 |
| Bogacka, I; Kaminski, T; Okrasa, S; Przala, J; Siawrys, C | 1 |
| Hansen, ST; Hayward, MD; Low, MJ; Pintar, JE | 1 |
| Clithero, AD; Leitermann, RJ; Sun, HS; Terashvili, M; Tseng, LF; Wu, HE | 1 |
| Guo, ZL; Longhurst, JC; Moazzami, AR | 1 |
| Dziwinski, T; Majewski, P; Pawlak, J; Skwarlo-Sonta, K; Waloch, M | 1 |
| Lam, HA; Maidment, NT; Narayanan, S; Shoblock, J; Skoubis, PD | 1 |
| Baugh, MM; Bradford, CS; Moore, FL; Stanley, DJ; Walthers, EA | 1 |
| Dudas, B; Merchenthaler, I | 1 |
| Lin, BC; Liu, WY; Song, CY; Yang, J | 1 |
| Hayward, MD; Low, MJ | 1 |
| Chen, JM; Lin, BC; Liu, WY; Xu, HT; Yang, J; Yang, Y | 1 |
| Chavkin, C; Gendron, L; Pintar, JE | 1 |
| Bilkei-Gorzo, A; Klingmüller, D; Mauer, D; Michel, K; Racz, I; Zimmer, A | 1 |
| Barna, I; Darula, Z; Kató, E; Keresztes, A; Mergl, Z; Rónai, AZ; Szemenyei, E; Tóth, G | 1 |
| Dieamant, Gde C; Eberlin, S; Nogueira, C; Queiroz, ML; Velazquez Pereda, Mdel C; Werka, RM | 1 |
| Bilkei-Gorzó, A; Cichon, S; Franke, PE; Fürst, R; Gunnar, A; Karpushova, A; Maier, W; Montag, C; Nöthen, M; Osby, U; Racz, I; Reuter, M; Schürmann, B; Schütz, C; Strohmaier, J; Terenius, L; Wienker, TF; Zimmer, A | 1 |
| Le, W; Ondo, WG; Walters, AS; Zhu, W | 1 |
| Bolte, C; Newman, G; Schultz, Jel J | 1 |
| Kennedy, RT; Li, Q; Zubieta, JK | 1 |
| Chen, W; Marvizón, JC; Murphy, N | 1 |
| Condamine, E; Costentin, J; Courchay, K; Davoust, D; Leprince, J; Mayer, C; Rego, JC; Vaudry, H | 1 |
| Friedman, TC; Hamid, A; Lutfy, K; Marquez, P; Nguyen, K; Parikh, D; Tseng, A | 1 |
| Hao, F; Li, P; Liang, JY; Pan, YJ; Qiu, PY; Wang, DX; Yang, J; Zhang, J | 1 |
| Kovalitskaya, YA; Navolotskaya, EV | 1 |
| Funkelstein, L; Hook, V | 1 |
| Ding, XY; Guo, MW; Ji, B; Li, CH; Ren, XX; Zhang, LF; Zhao, YF; Zhu, J | 1 |
| Garg, M; Hamid, A; Lutfy, K; Marquez, P; Nguyen, K; Tseng, A | 1 |
| Dudas, B; Grignol, G; Kiczek, M; Merchenthaler, I; Olsen, J; Peroski, M | 1 |
| Chou, AH; Day, YJ; Lee, CM; Lee, HC; Liao, CC; Lin, YC; Liou, JT; Mao, CC | 1 |
| Chen, ZY; Fu, X; Wang, H; Xu, H; Xu, W | 1 |
| Cai, R; He, L; Hu, L; Song, X; Wu, Z; Yu, Q; Zhang, C; Zheng, B | 1 |
| Maidment, NT; Mendez, IA; Murphy, NP; Ostlund, SB | 1 |
| Cerda-Cristerna, B; Chavarria-Bolaños, D; Flores-Reyes, H; Lombana-Sanchez, N; Pozos-Guillen, A | 1 |
| Appleyard, CB; Cruz, ML; Flores, I; Hernández, S; Hernández-López, A; Palermo, K; Thompson, KJ; Torres-Reverón, A | 1 |
| Chou, LW; Hong, CZ; Hsieh, YL; Liu, SY; Yang, CC | 1 |
| Guo, CQ; Li, XH; Liu, NG; Sun, HM; Wu, HX; Xu, H | 1 |
| Gong, XY; Hu, XY; Jia, LY; Lin, W; Luo, JX; Wang, YY; Wen, DC | 1 |
| Garduño-Gutiérrez, R; León-Olea, M; Rodríguez-Manzo, G | 1 |
| Buhler, AVK; Quock, RM; Tachibana, S; Zhang, Y | 1 |
| Berezin, CT; Cleymaet, AM; Vigh, J | 1 |
| Cai, H; Cui, L; Dong, J; Li, J; Qian, C; Qu, Y; Sun, F; Wang, H; Wang, Y | 1 |
| Calligaro, H; Cheng, K; Goel, V; Ibrahim, MM; Khanna, R; Kranz, T; Largent-Milnes, TM; Martin, LF; Moutal, A; Patwardhan, A; Washington, SM | 1 |
| Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L | 1 |
| Akil, H; Goldstein, A; Mansour, A; Meng, F; Thompson, RC; Watson, SJ; Xie, GX | 1 |
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
43 review(s) available for enkephalin, leucine and beta-endorphin
| Article | Year |
|---|---|
Mechanisms of pain perception in patients with silent myocardial ischemia.
Topics: beta-Endorphin; Coronary Disease; Enkephalins; Humans; Pain; Perception; Pressoreceptors; Receptors, Opioid; Sensory Thresholds | 1990 |
[The role of biologically active substances in the control of pain syndrome (review of the literature)].
Topics: Animals; beta-Endorphin; Brain; Endorphins; Enkephalins; Humans; Pain; Rats; Receptors, Opioid; Spinal Cord; Substance P | 1989 |
[Alcohol addiction: the role of oligopeptides in its central mechanisms].
Topics: Alcoholism; Angiotensin II; Animals; beta-Endorphin; Bradykinin; Brain; Enkephalins; Motivation; Oligopeptides | 1989 |
Endogenous opioid peptides and farm animal reproduction.
Topics: Anestrus; Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalins; Female; Luteinizing Hormone; Menstrual Cycle; Receptors, Opioid; Reproduction; Sheep | 1989 |
The endocrinology of the opioids.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; beta-Endorphin; Circadian Rhythm; Dynorphins; Endocrine Glands; Endorphins; Enkephalins; Female; Humans; Hypothalamo-Hypophyseal System; Islets of Langerhans; Melanocyte-Stimulating Hormones; Oxytocin; Pain; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Pregnancy; Rats; Receptors, Opioid; Shock; Stress, Physiological | 1985 |
Role of cholecystokinin and opioid peptides in control of food intake.
Topics: Amino Acid Sequence; Animals; Behavior, Animal; beta-Endorphin; beta-Lipotropin; Brain; Ceruletide; Cholecystokinin; Digestive System Physiological Phenomena; Dynorphins; Eating; Endorphins; Enkephalins; Fasting; Food; Humans; Immunologic Techniques; Kinetics; Morphine; Nervous System; Neurons; Obesity; Peptide Fragments; Protein Precursors; Receptors, Cell Surface; Receptors, Cholecystokinin; Satiation; Sincalide; Species Specificity; Structure-Activity Relationship; Tissue Distribution | 1986 |
Functional response of multiple opioid systems to chronic arthritic pain in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Arthritis; Arthritis, Experimental; Benzomorphans; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Morphine; Naloxone; Nociceptors; Pain; Pituitary Gland, Anterior; Protein Precursors; Pyrrolidines; Rats; Receptors, Opioid; Sensory Thresholds; Spinal Cord; Thalamus | 1986 |
Opioids and breathing.
Topics: Adult; Anesthesia; Animals; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; GABA Antagonists; Humans; Hypoxia; Morphine; Naloxone; Narcotics; Pulmonary Circulation; Respiration; Smoking | 1985 |
The role of opioids in the endocrine function of the pancreas.
Topics: Animals; beta-Endorphin; Biomechanical Phenomena; Chlorpropamide; Dogs; Eating; Endocrine Glands; Endorphins; Enkephalins; Ethanol; Flushing; Guinea Pigs; Humans; Islets of Langerhans; Male; Morphine; Naloxone; Pancreas; Pancreatic Hormones; Peptides; Protein Precursors; Rats; Sheep | 1986 |
Opioid peptides and epileptogenesis in the limbic system: cellular mechanisms.
Topics: Animals; beta-Endorphin; Biomechanical Phenomena; Endorphins; Enkephalins; Epilepsy; Hippocampus; Limbic System; Rats; Tissue Distribution | 1986 |
The many possible roles of opioids and related peptides in stress-induced analgesia.
Topics: Analgesia; Animals; beta-Endorphin; Brain; Electric Stimulation; Endorphins; Enkephalins; Male; Pain; Pro-Opiomelanocortin; Protein Precursors; Rats; Sensory Thresholds; Stress, Physiological; Time Factors | 1986 |
Opioid peptides: a role in sudden infant death syndrome?
Topics: beta-Endorphin; Central Nervous System; Endorphins; Enkephalins; Female; Humans; Infant, Newborn; Pregnancy; Respiration; Sudden Infant Death | 1986 |
Neuroendocrinology of opioid peptides and their role in the control of gonadotropin and prolactin secretion.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Cushing Syndrome; DNA, Recombinant; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Gonadotropins; Humans; Hypothalamus; Luteinizing Hormone; Menstrual Cycle; Naloxone; Ovary; Pituitary Hormone-Releasing Hormones; Prolactin; Receptors, Opioid | 1985 |
Endogenous opioid peptides and hypothalamo-pituitary function.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Endorphins; Enkephalins; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Male; Morphine; Naloxone; Prolactin; Rats; Stress, Physiological; Thyrotropin; Vasopressins | 1986 |
[Endogenous opioid systems].
Topics: Animals; beta-Endorphin; Brain; Endorphins; Enkephalins; Humans; Pain; Protein Precursors; Receptors, Opioid | 1985 |
[Opioid peptides].
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Cattle; Endorphins; Enkephalins; Gene Expression Regulation; Pro-Opiomelanocortin; Protein Precursors | 1984 |
Endorphins, opiate receptors and their evolving biology.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Central Nervous System; Endorphins; Enkephalins; Humans; Lithium; Narcotics; Neurotransmitter Agents; Opioid-Related Disorders; Phylogeny; Pituitary Gland; Receptors, Opioid; Sodium; Solubility | 1981 |
Central distribution of opioid peptides.
Topics: Animals; Basal Ganglia; beta-Endorphin; Central Nervous System; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Fluorescent Antibody Technique; Neural Pathways; Neurons; Rats; Spinal Cord; Subcellular Fractions; Synapses; Tissue Distribution; Trigeminal Nucleus, Spinal | 1983 |
Biosynthesis and distribution of opioid peptides.
Topics: Adrenal Medulla; Adrenocorticotropic Hormone; Animals; beta-Endorphin; beta-Lipotropin; Brain; Dynorphins; Endorphins; Enkephalins; Gastric Mucosa; Humans; Ileum; Melanocyte-Stimulating Hormones; Pituitary Gland; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors | 1983 |
Multiple opiate receptors and their functional significance.
Topics: Animals; beta-Endorphin; Brain; Cyclazocine; Dynorphins; Endorphins; Enkephalins; Ethylketocyclazocine; Morphine; Receptors, Opioid; Tissue Distribution | 1983 |
[Endorphins: structure, role and biogenesis].
Topics: Adrenocorticotropic Hormone; Analgesia; Animals; Behavior; beta-Endorphin; beta-Lipotropin; Brain; Chemical Phenomena; Chemistry; Endorphins; Enkephalins; Growth Hormone; Humans; Hydrocortisone; Neurotransmitter Agents; Pain; Pituitary Hormones; Prolactin; Rats; Thyrotropin | 1983 |
Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry.
Topics: Acetylcholine; Afferent Pathways; Analgesics; Animals; beta-Endorphin; Brain Stem; Dynorphins; Endorphins; Enkephalins; Medulla Oblongata; Models, Biological; Neural Pathways; Neurons; Neurotensin; Norepinephrine; Pain; Peptide Fragments; Periaqueductal Gray; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors; Spinal Cord; Stress, Physiological | 1984 |
Recurrent pains in children: an overview and an approach.
Topics: Attitude to Health; beta-Endorphin; Child; Child Development; Diagnostic Tests, Routine; Endorphins; Enkephalins; Ethnicity; Family; Female; Humans; Male; Medical History Taking; Neurotransmitter Agents; Nociceptors; Pain; Pain Management; Personality; Physical Examination; Psychology, Child; Recurrence; Sensation; Sensory Thresholds; Sex Factors; Synaptic Transmission | 1984 |
Multiple opioid receptor systems in brain and spinal cord: Part I.
Topics: Animals; Autoradiography; Bacterial Outer Membrane Proteins; beta-Endorphin; Binding Sites; Binding, Competitive; Biological Assay; Brain Chemistry; Dynorphins; Endorphins; Enkephalins; Humans; In Vitro Techniques; Ligands; Magnesium; Naloxone; Narcotics; Porins; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma; Receptors, Virus; Spinal Cord; Structure-Activity Relationship | 1984 |
Brain opiates.
Topics: Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Autoradiography; beta-Endorphin; Brain Chemistry; Endorphins; Enkephalins; Humans; Narcotics; Pituitary Gland; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors; Receptors, Opioid; Spinal Cord; Tissue Distribution | 1982 |
Neurochemistry of the vertebrate olfactory bulb.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; beta-Alanine; beta-Endorphin; beta-Lipotropin; Biogenic Amines; Carnosine; Catecholamines; Dopamine; Endorphins; Enkephalins; Epinephrine; gamma-Aminobutyric Acid; Glutamates; Glycine; Gonadotropin-Releasing Hormone; Histamine; Homocysteine; Insulin; Nerve Tissue Proteins; Neurotensin; Neurotransmitter Agents; Norepinephrine; Olfactory Bulb; Oxytocin; Serotonin; Substance P; Synapses; Taurine; Thyrotropin-Releasing Hormone; Vasopressins; Vertebrates | 1983 |
[Brain and intestinal peptides and endocrinological tests].
Topics: beta-Endorphin; Brain Chemistry; Cholecystokinin; Endorphins; Enkephalins; Female; Gastrins; Humans; Male; Nerve Tissue Proteins; Neurotensin; Somatostatin; Substance P; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1984 |
The role of opioid peptides in memory and learning.
Topics: Amnesia; Animals; beta-Endorphin; Brain; Dopamine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Humans; Learning; Memory; Naloxone; Naltrexone; Norepinephrine; Rats | 1980 |
Localization and opiate receptor binding of enkephalin, CCK and ACTH/beta-endorphin in the rat central nervous system.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Brain; Central Nervous System; Cholecystokinin; Endorphins; Enkephalins; Neurons; Rats; Receptors, Opioid | 1981 |
Comparative immunocytochemical localization of putative opioid ligands in the central nervous system.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Brain; Cholecystokinin; Endorphins; Enkephalins; Guinea Pigs; Histocytochemistry; Immunochemistry; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord | 1981 |
Endorphinlike drugs.
Topics: Animals; beta-Endorphin; Cardiovascular System; Central Nervous System; Digestive System; Endocrine Glands; Endorphins; Enkephalins; Humans; Mental Disorders; Pain | 1982 |
[The physiopathology of opioid peptides].
Topics: Analgesia; Animals; Asthma; beta-Endorphin; Diabetes Mellitus; Endorphins; Enkephalins; Epilepsy; Humans; Mental Disorders; Pituitary Hormones, Anterior; Receptors, Opioid; Tissue Distribution | 1982 |
Endogenous opioid peptides: review of physiological, pharmacological and clinical aspects.
Topics: Animals; beta-Endorphin; Blood-Brain Barrier; Brain; Endorphins; Enkephalins; Humans; Nociceptors; Peptides; Rats; Schizophrenia; Stress, Physiological; Synaptic Transmission | 1982 |
Minireview. Peptides and the blood-brain barrier.
Topics: Adrenocorticotropic Hormone; Angiotensins; Animals; beta-Endorphin; Biological Transport, Active; Blood-Brain Barrier; Calcitonin; Diffusion; Eating; Endorphins; Enkephalins; Gonadotropin-Releasing Hormone; Half-Life; Humans; Insulin; Melanocyte-Stimulating Hormones; Molecular Weight; Oxytocin; Peptides; Sexual Behavior, Animal; Vasopressins | 1983 |
Biosynthesis of the enkephalins and enkephalin-containing polypeptides.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Brain; Chemical Phenomena; Chemistry; Endorphins; Enkephalins; Humans; Molecular Weight; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors | 1983 |
Adrenal-pituitary axis and the opiate system; corticosteroid-adrencorticotropic hormones and the opiate system.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Alcohol Drinking; Analgesia; Animals; Appetite; beta-Endorphin; Brain Chemistry; Circadian Rhythm; Drug Interactions; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Feedback; Humans; Mice; Pituitary-Adrenal System; Rats; Receptors, Opioid; Stress, Physiological | 1983 |
Endogenous opioids. Histochemistry, neurophysiology, and pharmacology.
Topics: Analgesia; Animals; Behavior; beta-Endorphin; Brain; Central Nervous System; Chemical Phenomena; Chemistry; Electrophysiology; Endorphins; Enkephalin, Leucine; Enkephalins; Hippocampus; Humans; Receptors, Opioid | 1983 |
Neuroendocrine primary small cell carcinoma of the breast. Report of a case and review of the literature.
Topics: Aged; beta-Endorphin; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Small Cell; Chromogranins; Cytoplasm; Enkephalin, Leucine; Female; Humans; Immunohistochemistry; Keratins; Mammography; Mastectomy, Modified Radical; Phosphopyruvate Hydratase; Radiotherapy, Adjuvant | 1995 |
Peptidases in the CNS: formation of biologically active, receptor-specific peptide fragments.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Central Nervous System; Endopeptidases; Enkephalins; Humans; Molecular Sequence Data; Neuropeptides; Neurotensin; Peptide Fragments; Protein Precursors; Protein Processing, Post-Translational; Receptors, Cell Surface | 1993 |
Allelic and somatic variations in the endogenous opioid system of humans.
Topics: Alleles; beta-Endorphin; Enkephalins; Genetic Predisposition to Disease; Humans; Polymorphism, Genetic; Protein Precursors; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance-Related Disorders | 2001 |
Conformational analysis of opioid peptides in the solid states and the membrane environments by NMR spectroscopy.
Topics: beta-Endorphin; Dynorphins; Enkephalin, Leucine; Enkephalins; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Opioid Peptides; Protein Conformation; Receptors, Opioid, kappa; Structure-Activity Relationship | 2004 |
Three-dimensional representation of the neurotransmitter systems of the human hypothalamus: inputs of the gonadotrophin hormone-releasing hormone neuronal system.
Topics: beta-Endorphin; Cell Communication; Corticotropin-Releasing Hormone; Enkephalin, Leucine; Feedback, Physiological; Female; Fertility; Galanin; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Imaging, Three-Dimensional; Male; Neural Pathways; Neurons; Neuropeptide Y; Neurotransmitter Agents; Substance P; Tissue Distribution; Tyrosine 3-Monooxygenase | 2006 |
Nonopioid effect of β-endorphin.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Endocrine System; Enkephalins; Humans; Immune System; Immunoglobulin Fc Fragments; Molecular Sequence Data; Nervous System; Receptors, Opioid | 2011 |
6 trial(s) available for enkephalin, leucine and beta-endorphin
| Article | Year |
|---|---|
Chlorpropamide alcohol flush and circulating met-enkephalin: a positive link.
Topics: beta-Endorphin; Chlorpropamide; Diabetes Mellitus; Double-Blind Method; Drug Interactions; Endorphins; Enkephalin, Methionine; Enkephalins; Erythema; Face; Female; Humans; Male; Wine | 1981 |
Doxepin effects on chronic pain, depression and plasma opioids.
Topics: Adult; Aged; beta-Endorphin; Chronic Disease; Depression; Double-Blind Method; Doxepin; Endorphins; Enkephalins; Female; Humans; Male; Middle Aged; Pain; Placebos; Random Allocation; Sensory Thresholds; Sleep | 1982 |
Doxepin's effects on chronic pain and depression: a controlled study.
Topics: beta-Endorphin; Chronic Disease; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Endorphins; Enkephalins; Female; Humans; Male; Middle Aged; Pain; Placebos; Psychiatric Status Rating Scales; Random Allocation; Time Factors | 1984 |
[Basal secretion of endogenous opioids after intravenous naloxone].
Topics: beta-Endorphin; Enkephalin, Leucine; Humans; Male; Naloxone | 1994 |
Beta-endorphin but not metenkephalin counteracts adenosine-provoked angina pectoris-like pain.
Topics: Adult; Angina Pectoris; beta-Endorphin; Dose-Response Relationship, Drug; Double-Blind Method; Enkephalins; Humans; Male; Middle Aged; Pain | 1996 |
Neuroimmunomodulatory compound for sensitive skin care: in vitro and clinical assessment.
Topics: Administration, Cutaneous; Analysis of Variance; Antioxidants; beta-Endorphin; Calcitonin Gene-Related Peptide; Carnosine; Cells, Cultured; Cytokines; Double-Blind Method; Enkephalins; Humans; Immunoenzyme Techniques; Keratinocytes; Middle Aged; Peripheral Nervous System Agents; Plant Extracts; Rhodiola; Skin; Substance P; Surveys and Questionnaires; Ultraviolet Rays; Water Loss, Insensible | 2008 |
474 other study(ies) available for enkephalin, leucine and beta-endorphin
| Article | Year |
|---|---|
The brain's opium (human beta-endorphin)
Topics: Animals; beta-Endorphin; Brain; Endorphins; Enkephalins; Humans; Pain; Pituitary Gland; Rats; Receptors, Opioid | 1979 |
[The biopolymer metabolism of the connective tissue in the aorta under intraventricular injections of neuropeptides].
Topics: Animals; Aorta; beta-Endorphin; Biopolymers; Connective Tissue; Enkephalin, Leucine; Injections, Intraventricular; Neuropeptides; Rabbits; Substance P; Time Factors | 1992 |
Immunosuppressive effect of delta-opioid receptor antagonist on xenogeneic mixed lymphocyte reaction.
Topics: Analgesics; beta-Endorphin; Cell Survival; Cells, Cultured; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Humans; Immunosuppressive Agents; Indoles; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Morphinans; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta | 1992 |
The tail-flick inhibition induced by beta-endorphin administered intrathecally is mediated by activation of kappa- and mu-opioid receptors in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Yohimbine | 1992 |
Differential development of beta-endorphin and mu opioid binding sites in mouse brain.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Binding, Competitive; Brain; Dihydromorphine; Embryonic and Fetal Development; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Radioimmunoassay; Receptors, Opioid; Receptors, Opioid, mu | 1992 |
Further characterization of alpha N-acetyl beta-endorphin-(1-31) regulatory activity, I: Effect on opioid- and alpha 2-mediated supraspinal antinociception in mice.
Topics: Analgesia; Analgesics; Animals; beta-Endorphin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; GTP-Binding Proteins; Injections, Intraventricular; Male; Mice; Nociceptors; Pain Measurement; Peptides; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, mu | 1992 |
Estrogen suppresses mu-opioid- and GABAB-mediated hyperpolarization of hypothalamic arcuate neurons.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Estradiol; Evoked Potentials; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; In Vitro Techniques; Membrane Potentials; Neurons; Ovariectomy; Receptors, Opioid; Receptors, Opioid, mu; Tetrodotoxin | 1992 |
[Activation of delta-opiate receptor simultaneously stimulates ACTH beta-endorphin and prolactin release].
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Stress, Physiological | 1992 |
Identification and characterization of delta opioid binding sites in the bovine pineal.
Topics: Analgesics; Animals; beta-Endorphin; Binding Sites; Cattle; Culture Techniques; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; HEPES; Pineal Gland; Receptors, Opioid; Receptors, Opioid, delta | 1992 |
Pentobarbital attenuates antinociception induced by i.c.v. morphine but not beta-endorphin in the mouse.
Topics: Animals; beta-Endorphin; Drug Interactions; Enkephalin, Leucine; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Naltrexone; Narcotic Antagonists; Nociceptors; Pentobarbital; Receptors, Opioid | 1992 |
Opioid receptors mediating antinociception from beta-endorphin and morphine in the periaqueductal gray.
Topics: Amino Acid Sequence; Analgesics; Animals; beta-Endorphin; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Male; Molecular Sequence Data; Morphine; Naltrexone; Narcotic Antagonists; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid | 1992 |
Influence of opioids on CSF vasopressin concentration in newborn pigs.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Analysis of Variance; Animals; Animals, Newborn; beta-Endorphin; Cerebral Arteries; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Naloxone; Pyrrolidines; Swine; Vasopressins | 1992 |
Neuroanatomical sites mediating the central actions of beta-endorphin as mapped by changes in glucose utilization: involvement of mu opioid receptors.
Topics: Animals; Autoradiography; Behavior, Animal; beta-Endorphin; Brain; Dose-Response Relationship, Drug; Enkephalin, Leucine; Glucose; Injections, Intraventricular; Male; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Somatostatin | 1992 |
[Effect of opioid peptides on progesterone production by rat luteal cells in vitro].
Topics: Animals; beta-Endorphin; Cells, Cultured; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Luteal Cells; Progesterone; Rats; Rats, Sprague-Dawley | 1992 |
The pressor response to central administration of beta-endorphin results from a centrally mediated increase in noradrenaline release and adrenaline secretion.
Topics: Animals; beta-Endorphin; Blood Pressure; Brain; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Epinephrine; Injections, Intraventricular; Male; Naloxone; Norepinephrine; Rabbits | 1991 |
Measurement of beta-endorphin in human plasma by high-performance liquid chromatography with electrochemical detection: validation of a method employing the simultaneous purification and concentration of beta-endorphin.
Topics: Aprotinin; beta-Endorphin; Chromatography, High Pressure Liquid; Electrochemistry; Enkephalin, Leucine; Enkephalin, Methionine; Heparin; Humans; Reproducibility of Results; Temperature | 1992 |
[Detection of opioids in an extract of oak silkworm cocoons].
Topics: Animals; beta-Endorphin; Bombyx; Enkephalin, Leucine; Narcotics; Pupa; Radioimmunoassay; Radioligand Assay | 1992 |
Chronic naltrexone treatment of rats: effects on gastrointestinal opioid peptide content.
Topics: Animals; beta-Endorphin; Digestive System; Duodenum; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Jejunum; Male; Naltrexone; Pyloric Antrum; Radioimmunoassay; Radioligand Assay; Rats; Rats, Wistar | 1992 |
[A study of opioid peptides in synovial fluid and synovial tissue in patients with rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; beta-Endorphin; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Male; Middle Aged; Stress, Psychological; Synovial Fluid; Synovial Membrane | 1992 |
Cholecystokinin administered intrathecally selectively antagonizes intracerebroventricular beta-endorphin-induced tail-flick inhibition in the mouse.
Topics: Analgesia; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Peptide Fragments; Receptors, Cholecystokinin; Sincalide | 1992 |
[Beta-endorphin- and leucine enkephalin concentrations in marathon athletes].
Topics: beta-Endorphin; Enkephalin, Leucine; Humans; Male; Running | 1992 |
Naloxone blocks opioid peptide release in N. accumbens and amygdala elicited by morphine injected into periaqueductal gray.
Topics: Amygdala; Animals; beta-Endorphin; Enkephalins; Male; Microinjections; Morphine; Naloxone; Nucleus Accumbens; Perfusion; Periaqueductal Gray; Rabbits; Radioimmunoassay; Stereotaxic Techniques | 1992 |
Ethanol-induced increase in endogenous dopamine release may involve endogenous opiates.
Topics: Animals; beta-Endorphin; Dopamine; Endorphins; Enkephalin, Leucine; Ethanol; Levodopa; Male; Naloxone; Narcotic Antagonists; Potassium; Rats; Rats, Inbred Strains | 1992 |
Neurochemical and morphological evidence of an antinociceptive neural pathway from nucleus raphe dorsalis to nucleus accumbens in the rabbit.
Topics: Animals; beta-Endorphin; Brain Chemistry; Enkephalins; Horseradish Peroxidase; Immunohistochemistry; Injections; Male; Morphine; Neural Pathways; Nociceptors; Nucleus Accumbens; Periaqueductal Gray; Rabbits; Radioimmunoassay; Raphe Nuclei; Serotonin | 1992 |
Opioid receptor subtype involvement in maternal behavior in lactating rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Lactation; Maternal Behavior; Morphine; Phenazocine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Influence of chronic opioid delta receptor antagonism on blood pressure development and tissue contents of catecholamines and endogenous opioids in spontaneously hypertensive rats.
Topics: Animals; beta-Endorphin; Blood Pressure; Enkephalin, Leucine; Epinephrine; Male; Narcotic Antagonists; Norepinephrine; Rats; Rats, Inbred SHR; Receptors, Opioid, delta; Time Factors; Tissue Distribution | 1991 |
Rapid agonist-induced loss of 125I-beta-endorphin opioid receptor sites in NG108-15, but not SK-N-SH neuroblastoma cells.
Topics: Analgesics; Animals; beta-Endorphin; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Humans; Mice; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1991 |
In vitro effect of high doses of morphine on Con A induced lymphokine production.
Topics: Animals; beta-Endorphin; Cell Survival; Cells, Cultured; Clone Cells; Colforsin; Concanavalin A; Cyclic AMP; Depression, Chemical; Dinoprostone; Dose-Response Relationship, Drug; Enkephalins; Female; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Protein Biosynthesis; Receptors, Opioid; Spleen; T-Lymphocytes, Helper-Inducer | 1991 |
Sleep deprivation decreases mu and delta opioid receptor binding in the rat limbic system.
Topics: Animals; Arousal; Behavior, Animal; beta-Endorphin; Brain Chemistry; Densitometry; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Limbic System; Male; Membranes; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sleep Deprivation | 1991 |
Neurons in the rat arcuate nucleus are hyperpolarized by GABAB and mu-opioid receptor agonists: evidence for convergence at a ligand-gated potassium conductance.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; beta-Endorphin; Cell Polarity; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
[Effect of surgical stress on the dynamics of endogenous opiates and various mechanisms of their metabolism].
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Anesthesia, Endotracheal; Anesthesia, Epidural; beta-Endorphin; Chronic Disease; Enkephalin, Leucine; Humans; Insulinoma; Intraoperative Care; Pain, Postoperative; Pancreatic Neoplasms; Pancreatitis; Postoperative Care; Stress, Physiological | 1991 |
Stereoselective effect of morphine on antinociception and endogenous opioid peptide levels in plasma but not cerebrospinal fluid of dogs.
Topics: Animals; Behavior, Animal; beta-Endorphin; Dogs; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Subcutaneous; Morphine; Nociceptors; Pain Measurement; Stereoisomerism; Tritium | 1991 |
Opioids in cerebrospinal fluid in hypotensive newborn pigs.
Topics: Animals; Animals, Newborn; beta-Endorphin; Cerebral Arteries; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hemorrhage; Hypotension; Muscle, Smooth, Vascular; Radioimmunoassay; Radioligand Assay; Reference Values; Swine; Vasodilation | 1991 |
Naturally occurring opioid receptor agonists stimulate adenylate cyclase activity in rat olfactory bulb.
Topics: Adenylyl Cyclases; Alkaloids; Animals; beta-Endorphin; Calcium; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enzyme Activation; Guanosine Triphosphate; Intracellular Fluid; Kinetics; Male; Naloxone; Olfactory Bulb; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Opioid; Staurosporine; Stimulation, Chemical | 1991 |
The electrically stimulated release of [3H]noradrenaline from nucleus tractus solitarii slices in vitro is modulated via mu-opioid receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Medulla Oblongata; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid | 1991 |
Evidence for enkephalin- and endorphin-immunoreactive cells in the anterior pituitary of the axolotl Ambystoma mexicanum.
Topics: Ambystoma mexicanum; Animals; Antibodies; beta-Endorphin; Cross Reactions; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Fluorescent Antibody Technique; Immunohistochemistry; Nerve Fibers; Pituitary Gland, Anterior | 1991 |
Inhibition by opioids of phagocytosis in peritoneal macrophages.
Topics: Animals; beta-Endorphin; Drug Tolerance; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Erythrocytes; Macrophages; Mice; Morphine; Naloxone; Peritoneal Cavity; Phagocytosis; Sheep | 1991 |
Beta-endorphin: a highly selective endogenous opioid agonist for presynaptic mu opioid receptors.
Topics: Animals; beta-Endorphin; Brain; Culture Techniques; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Neurotransmitter Agents; Norepinephrine; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
mu-receptor mediates elevated glucose and corticosterone after third ventricle injection of opioid peptides.
Topics: Animals; beta-Endorphin; Blood Glucose; Cerebral Ventricles; Corticosterone; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fatty Acids, Nonesterified; Injections, Intraventricular; Male; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Effects of dexfenfluramine and opioid peptides, alone or in combination, on food intake and brain serotonin turnover in rats.
Topics: Animals; beta-Endorphin; Brain; Drug Interactions; Dynorphins; Eating; Endorphins; Enkephalin, Leucine; Female; Fenfluramine; Naltrexone; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Neuropeptide content in pancreas and pituitary of obese and diabetes mutant mice: strain and sex differences.
Topics: Animals; beta-Endorphin; Diabetes Mellitus, Experimental; Enkephalin, Leucine; Enkephalin, Methionine; Female; Galanin; In Vitro Techniques; Insulin; Male; Mice; Mice, Mutant Strains; Mice, Obese; Neuropeptides; Obesity; Pancreas; Peptides; Pituitary Gland; Reference Values; Sex Factors; Species Specificity | 1990 |
Neuropeptide-immunoreactive cells in human thymus.
Topics: beta-Endorphin; Cell Differentiation; Child, Preschool; Enkephalin, Leucine; Enkephalin, Methionine; Epithelium; Humans; Infant; Infant, Newborn; Intercellular Junctions; Neuroimmunomodulation; Neuropeptides; Substance P; T-Lymphocytes; Thymus Gland | 1990 |
Neurochemical studies on the mesolimbic circuitry of antinociception.
Topics: Amygdala; Animals; beta-Endorphin; Enkephalins; Limbic System; Male; Microinjections; Morphine; Neurons; Nucleus Accumbens; Organ Specificity; Pain; Perfusion; Rabbits | 1991 |
Cholera toxin and pertussis toxin on opioid- and alpha 2-mediated supraspinal analgesia in mice.
Topics: Analgesia; Animals; beta-Endorphin; Cerebral Ventricles; Cholera Toxin; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; GTP-Binding Proteins; Injections, Intraventricular; Male; Mice; Morphine; Narcotics; Pain; Pertussis Toxin; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella | 1991 |
Enhanced potency of receptor-selective opioids after acute burn injury.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; beta-Endorphin; Burns; Corticosterone; Dose-Response Relationship, Drug; Enkephalins; Injections, Intravenous; Male; Morphine; Pyrrolidines; Rats; Rats, Inbred Strains | 1991 |
[Opioid peptides in cerebrospinal fluids of epileptic patients].
Topics: Adolescent; Adult; beta-Endorphin; Child; Enkephalin, Leucine; Enkephalin, Methionine; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged | 1991 |
Sympathoadrenal control by paraventricular hypothalamic beta-endorphin in hypertension.
Topics: Animals; Behavior, Animal; beta-Endorphin; Blood Glucose; Blood Pressure; Catecholamines; Diffusion; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Heart Rate; Hypertension; Male; Naltrexone; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1991 |
[Neurochemical and morphological study of the analgesic pathway in the midbrain-limbic system].
Topics: beta-Endorphin; Enkephalins; Humans; Limbic System; Mesencephalon; Neural Pathways; Nociceptors | 1991 |
Proenkephalin A and proopiomelanocortin peptides in human cerebrospinal fluid.
Topics: beta-Endorphin; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Enkephalins; Humans; Hydrolysis; Mass Spectrometry; Pro-Opiomelanocortin; Protein Precursors; Radioimmunoassay; Radioligand Assay; Receptors, Opioid | 1990 |
Evidence for phosphatidylinositol anchorage of opioid binding proteins in rat brain.
Topics: Animals; Autoradiography; beta-Endorphin; Brain Chemistry; Corpus Striatum; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Iodine Radioisotopes; Membranes; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Protein Binding; Rats; Receptors, Opioid; Thalamus | 1990 |
Hemodynamic responses of conscious rats following intrathecal injections of prodynorphin-derived opioids: independence of action of intrathecal arginine vasopressin.
Topics: Animals; Arginine Vasopressin; beta-Endorphin; Blood Pressure; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Heart Rate; Hemodynamics; Injections, Spinal; Male; Narcotics; Norepinephrine; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred Strains | 1990 |
Involvement of central mu and delta opioid receptors in mediating the reinforcing effects of beta-endorphin in the rat.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Conditioning, Operant; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Somatostatin | 1990 |
The occurrence and receptor specificity of endogenous opioid peptides within the pancreas and liver of the rat. Comparison with brain.
Topics: Animals; beta-Endorphin; Brain; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Immunohistochemistry; Liver; Male; Pancreas; Radioimmunoassay; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1990 |
Different types of opioid receptors mediating analgesia induced by morphine, DAMGO, DPDPE, DADLE and beta-endorphin in mice.
Topics: Analgesia; Animals; beta-Endorphin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Reaction Time; Receptors, Opioid; Somatostatin | 1990 |
Prostanoids modulate opioid cerebrovascular responses in newborn pigs.
Topics: Administration, Topical; Animals; Animals, Newborn; Arachnoid; Arterioles; beta-Endorphin; Blood Gas Analysis; Cerebrovascular Circulation; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Hydrogen-Ion Concentration; Indomethacin; Male; Pia Mater; Prostaglandins; Swine; Vasodilation | 1990 |
Trophic effects of enkephalin, beta-endorphine and dynorphine on ventral spinal cord in culture.
Topics: Animals; Axons; beta-Endorphin; Cells, Cultured; Dynorphins; Enkephalins; Rats; Rats, Inbred Strains; Spinal Cord | 1990 |
Identification of the opioid receptor types mediating beta-endorphin-induced alterations in dopamine release in the nucleus accumbens.
Topics: Analgesics; Animals; beta-Endorphin; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Male; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Opioid; Somatostatin | 1990 |
Ovarian contents of immunoreactive beta-endorphin and alpha-N-acetylated opioid peptides in rats.
Topics: Acetylation; Animals; beta-Endorphin; Chorionic Gonadotropin; Endorphins; Enkephalins; Female; Follicular Fluid; Gonadotropins, Equine; Ovary; Pseudopregnancy; Rats; Rats, Inbred Strains; Sexual Maturation | 1991 |
alpha N-acetyl derivatives of beta-endorphin-(1-31) and -(1-27) regulate the supraspinal antinociceptive activity of different opioids in mice.
Topics: Acetylation; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Pain; Structure-Activity Relationship; Tail; Time Factors | 1991 |
Different mechanisms mediating tail-flick inhibition induced by beta-endorphin, DAMGO and morphine from ROb and GiA in anesthetized rats.
Topics: Analgesia; Animals; beta-Endorphin; Brain Stem; Diffusion; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Methysergide; Morphine; Naloxone; Raphe Nuclei; Rats; Rats, Inbred Strains; Yohimbine | 1991 |
[The interaction between nucleus accumbens and amygdala in accelerating the release of enkephalins and beta-endorphin].
Topics: Amygdala; Animals; beta-Endorphin; Enkephalins; Male; Microinjections; Morphine; Nociceptors; Nucleus Accumbens; Rabbits | 1991 |
Responses of morphine dependent opioid neurones to stressors.
Topics: Animals; beta-Endorphin; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Morphine Dependence; Naloxone; Neurons; Pregnancy; Rats; Stress, Physiological; Tissue Distribution | 1990 |
[Opioid peptides in RA: modulation of immunologic mechanisms and mental states].
Topics: Adult; Aged; Arthritis, Rheumatoid; beta-Endorphin; Emotions; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Facial Expression; Female; Humans; Immunoglobulins; Leukocyte Count; Lymphocytes; Male; Middle Aged | 1990 |
A study on opioid peptides in CSF of patients with epilepsy.
Topics: Adolescent; Adult; Age Factors; beta-Endorphin; Cerebrospinal Fluid Proteins; Child; Enkephalin, Leucine; Enkephalin, Methionine; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Radioimmunoassay; Sex Factors | 1990 |
Immunocytochemical colocalization of progestin receptors and beta-endorphin or enkephalin in the hypothalamus of female guinea pigs.
Topics: Animals; beta-Endorphin; Enkephalins; Estradiol; Female; Guinea Pigs; Hypothalamus; Immunohistochemistry; Receptors, Progesterone; Tissue Distribution | 1990 |
Cross-linking of 125I-beta-endorphin to rat striatal mu- and delta-opioid receptors under physiological conditions: evidence for an opioid receptor complex.
Topics: Animals; beta-Endorphin; Binding, Competitive; Corpus Striatum; Cross-Linking Reagents; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Iodine Radioisotopes; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1990 |
Lack of antinociceptive cross-tolerance between intracerebroventricularly administered beta-endorphin and morphine or DPDPE in mice.
Topics: Analgesics; Animals; beta-Endorphin; Brain; Cross Reactions; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Receptors, Opioid | 1990 |
Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex.
Topics: Animals; beta-Endorphin; Binding Sites; Cattle; Cerebral Cortex; Corpus Striatum; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Oligopeptides; Proteins; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1990 |
Tolerance to delta- but not mu-opioid receptors in the spinal cord attenuates inhibition of the tail-flick response induced by beta-endorphin administered intracerebroventricularly in mice.
Topics: Animals; beta-Endorphin; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1990 |
Opioids modulate interleukin-1 production and secretion by bone-marrow macrophages.
Topics: Animals; beta-Endorphin; Bone Marrow Cells; Drug Synergism; Endorphins; Enkephalins; Interleukin-1; Lipopolysaccharides; Macrophages; Mice; Naloxone; Protein Precursors; Silicon Dioxide | 1990 |
Delta but not mu-opioid receptors in the spinal cord are involved in antinociception induced by beta-endorphin given intracerebroventricularly in mice.
Topics: Analgesia; Animals; beta-Endorphin; Enkephalin, Leucine; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1990 |
Involvement of multiple opiate receptors in opioid kindling.
Topics: Animals; beta-Endorphin; Convulsants; Endorphins; Enkephalin, Leucine; Kindling, Neurologic; Male; Morphine; Oligopeptides; Rats; Receptors, Opioid | 1990 |
[Plasma leucine enkephalin and beta-endorphin levels in patients with essential hypertension and the effects of captopril].
Topics: Adult; Aged; beta-Endorphin; Captopril; Enkephalin, Leucine; Female; Humans; Hypertension; Male; Middle Aged | 1990 |
Opioids hyperpolarize beta-endorphin neurons via mu-receptor activation of a potassium conductance.
Topics: Action Potentials; Animals; Bacterial Proteins; beta-Endorphin; Cell Membrane; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Antibody Technique; Fluorescent Dyes; Guinea Pigs; Lysine; Membrane Potentials; Microscopy, Fluorescence; Naloxone; Neurons; Potassium Channels; Receptors, Opioid; Receptors, Opioid, mu; Streptavidin; Thiocyanates | 1990 |
Effect of beta-endorphin on steroidogenesis by bovine luteal cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; beta-Endorphin; Cattle; Cells, Cultured; Corpus Luteum; Dinoprost; Dose-Response Relationship, Drug; Enkephalin, Leucine; Female; Pregnancy; Progesterone | 1990 |
Dynorphin and neoendorphin peptides decrease dorsal root ganglion neuron calcium-dependent action potential duration.
Topics: Action Potentials; Animals; beta-Endorphin; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Ganglia, Spinal; Ion Channels; Mice; Naloxone; Protein Precursors; Receptors, Opioid; Sodium; Time Factors | 1985 |
[Effect of opioid peptides on nervous tissue in vitro].
Topics: Animals; Animals, Newborn; beta-Endorphin; Culture Techniques; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; gamma-Endorphin; Ganglia, Spinal; Ganglia, Sympathetic; Organ Specificity; Rats; Rats, Inbred Strains | 1985 |
Inhibition of shock-elicited ultrasonic vocalization by opioid peptides in the rat: a psychotropic effect.
Topics: Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalins; Fear; Injections, Intraventricular; Male; Psychotropic Drugs; Rats; Rats, Inbred Strains; Substance P; Vocalization, Animal | 1986 |
The effects of endorphins on mucous glycoprotein secretion from feline airways in vitro.
Topics: alpha-Endorphin; Animals; beta-Endorphin; Cats; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; gamma-Endorphin; Glycoproteins; Morphine; Mucus; Naloxone; Organ Culture Techniques; Secretory Rate; Trachea | 1987 |
Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.
Topics: Animals; beta-Endorphin; Electric Conductivity; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; GTP-Binding Proteins; Guinea Pigs; Ion Channels; Locus Coeruleus; Membrane Potentials; Narcotics; Neurons; Potassium; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
[Pressor effects of intracerebroventricularly administered substance P are mediated by enkephalins and beta-endorphin in rats].
Topics: Animals; beta-Endorphin; Blood Pressure; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Male; Rats; Substance P | 1987 |
Normalization of blood pressure and plasma concentrations of beta-endorphin and leucine-enkephalin in patients with primary hypertension after treatment with clonidine.
Topics: Adult; beta-Endorphin; Blood Pressure; Clonidine; Enkephalin, Leucine; Humans; Hydrocortisone; Hypertension; Male; Norepinephrine; Radioimmunoassay; Renin | 1987 |
Modulation of mesolimbic dopaminergic projections by beta-endorphin in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; beta-Endorphin; Cerebral Ventricles; Corpus Striatum; Dopamine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Homovanillic Acid; Injections, Intraventricular; Kinetics; Male; Morphine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reference Values; Septal Nuclei | 1989 |
[Function of the endogenous opioid system in hypoxic hypoxia].
Topics: Adrenal Glands; Animals; beta-Endorphin; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Hypoxia; Lactates; Male; Mice; Rats; Rats, Inbred Strains | 1989 |
Immunoreactive beta-endorphin and met- and leu-enkephalin contents in pancreas and pituitary of corpulent (cp/cp) rats.
Topics: Animals; beta-Endorphin; Enkephalin, Leucine; Enkephalin, Methionine; Male; Obesity; Pancreas; Pituitary Gland; Rats; Rats, Inbred SHR | 1989 |
Developmental patterns for pancreatic opioids in the rat.
Topics: Animals; beta-Endorphin; Enkephalins; Female; Fetus; Glucagon; Insulin; Islets of Langerhans; Male; Pancreas; Pregnancy; Radioimmunoassay; Rats; Rats, Inbred WF; Thyrotropin-Releasing Hormone | 1989 |
[Plasma levels of endogenous opioid peptides in patients with chronic colitis].
Topics: Adult; beta-Endorphin; Chronic Disease; Colitis; Colitis, Ulcerative; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Middle Aged | 1989 |
Down-regulation of proopiomelanocortin synthesis and beta-endorphin utilization in hypothalamus of morphine-tolerant rats.
Topics: Animals; beta-Endorphin; Corpus Striatum; Drug Tolerance; Enkephalin, Methionine; Enkephalins; Hypothalamus; Male; Morphine; Naltrexone; Pro-Opiomelanocortin; Protein Precursors; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger; Substance Withdrawal Syndrome | 1989 |
Localization of chromogranin A and B, beta-endorphin and enkephalins in the submandibular glands of mice.
Topics: Animals; beta-Endorphin; Chromogranins; Enkephalins; Immunohistochemistry; Male; Mice; Pancreas; Submandibular Gland | 1989 |
Influence of opioid peptides on learning and memory processes in the chick.
Topics: Animals; Attention; beta-Endorphin; Brain Mapping; Chickens; Discrimination Learning; Dominance, Cerebral; Dose-Response Relationship, Drug; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Memory; Mental Recall; Naloxone; Receptors, Opioid; Receptors, Opioid, delta; Visual Cortex | 1989 |
Guanine nucleotide regulation of [125I]beta-endorphin binding to NG108-15 and SK-N-SH cell membranes: specific cation requirements.
Topics: beta-Endorphin; Cations; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Glioma; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Hybrid Cells; Neuroblastoma; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride; Tumor Cells, Cultured | 1989 |
Cross-linking of human 125I-beta-endorphin to a mu-delta opioid receptor complex in rat striatum.
Topics: Animals; beta-Endorphin; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Iodine Radioisotopes; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1989 |
Opioid receptor selectivity of peptide models of beta-endorphin.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Molecular Sequence Data; Muscle Contraction; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1989 |
[Effects of ethanol on the concentration of neuropeptides, ACTH and corticosterone during immobilization stress].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Brain; Brain Chemistry; Corticosterone; Enkephalins; Ethanol; Immobilization; Male; Neuropeptides; Rats; Stress, Physiological | 1989 |
Effect of endogenous opioid peptides on TRH release from rat stomach in vitro.
Topics: Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Gastric Mucosa; In Vitro Techniques; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Stomach; Thyrotropin-Releasing Hormone | 1989 |
Computer analysis of the effect of beta-endorphin and dynorphin and related compounds on opioid binding to mouse brain membrane.
Topics: Animals; beta-Endorphin; Binding, Competitive; Brain; Cyclazocine; Dihydromorphine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Mice; Models, Neurological; Receptors, Opioid | 1989 |
Lack of mixed agonist-antagonist properties of [Gln8-Gly31]-beta h-EP-Gly-Gly-NH2 and [Arg9,19,24,28,29]-beta h-EP in the rat vas deferens neuroeffector junction: studies with naloxone, beta-funaltrexamine and ICI 174,864.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Leucine; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Neuroeffector Junction; Rats; Rats, Inbred Strains; Vas Deferens | 1989 |
Opioid-like activity in the cerebrospinal fluid of pain patients treated by electroacupuncture.
Topics: beta-Endorphin; Chromatography, High Pressure Liquid; Chronic Disease; Dynorphins; Electroacupuncture; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Pain; Pain Management; Radioimmunoassay | 1989 |
Change of Leu-enkephalin- and B-endorphin-like immunoreactivity in the hippocampus after electroconvulsive shock and electroacupuncture.
Topics: Animals; beta-Endorphin; Electroacupuncture; Electroconvulsive Therapy; Enkephalin, Leucine; Hippocampus; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
Effects of chlordecone administration on brain and pituitary peptide systems.
Topics: Aging; Animals; Animals, Newborn; beta-Endorphin; Brain; Castration; Chlordecone; Diet; Diethylstilbestrol; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Estrogens; Female; Insecticides; Luteinizing Hormone; Male; Nerve Tissue Proteins; Pituitary Gland, Anterior; Prolactin; Rats; Time Factors | 1985 |
Binding of naloxone to human T lymphocytes.
Topics: beta-Endorphin; Binding, Competitive; Blood Platelets; Culture Media; Enkephalin, Leucine; Enkephalin, Methionine; Glutathione; Humans; Kinetics; Morphine; Naloxone; Receptors, Opioid; Sonication; T-Lymphocytes | 1987 |
Comparison of [125I]beta-endorphin binding to rat brain and NG108-15 cells using a monoclonal antibody directed against the opioid receptor.
Topics: Animals; Antibodies, Monoclonal; beta-Endorphin; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Glioma; Immunoglobulin M; In Vitro Techniques; Iodine Radioisotopes; Male; Molecular Weight; Neuroblastoma; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1988 |
Varying expression of opioid receptors and GTP-binding proteins in human pheochromocytomas.
Topics: Adrenal Gland Neoplasms; beta-Endorphin; Cell Membrane; Cyclazocine; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; GTP-Binding Proteins; Humans; Pheochromocytoma; Receptors, Opioid | 1986 |
Binding to mu and delta opioid sites but not kappa sites is inhibited by Fab fragments from a monoclonal antibody directed against the opioid receptor.
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; beta-Endorphin; Cell Membrane; Cerebellum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Immunoglobulin Fab Fragments; Kinetics; Male; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1986 |
Selective effects of beta-endorphin infused into the hypothalamus, preoptic area and bed nucleus of the stria terminalis on the sexual and ingestive behaviour of male rats.
Topics: Animals; beta-Endorphin; Cholecystokinin; Enkephalin, Leucine; Feeding Behavior; Hypothalamus, Anterior; Male; Naloxone; Preoptic Area; Rats; Reaction Time; Receptors, Opioid; Sexual Behavior, Animal; Thiazines | 1987 |
Monoclonal anti-idiotypic antibodies to opioid receptors.
Topics: Animals; Antibodies, Monoclonal; Antigens; beta-Endorphin; Brain; Cell Membrane; Cyclic AMP; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybridomas; Immunoglobulin G; Immunoglobulin Idiotypes; Immunoglobulin M; Immunosorbent Techniques; Mice; Mice, Inbred BALB C; Naloxone; Rats; Receptors, Opioid; Tumor Cells, Cultured | 1988 |
Affinity crosslinking of 125I-labeled human beta-endorphin to cell lines possessing either mu- or delta-type opioid binding sites.
Topics: beta-Endorphin; Binding Sites; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1988 |
Opioid receptor selectivity of beta-endorphin in vitro and in vivo: mu, delta and epsilon receptors.
Topics: Analgesia; Animals; beta-Endorphin; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Gastric Emptying; Male; Mice; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 1988 |
Opioid peptides increase calcium uptake by synaptosomes from brain regions.
Topics: Animals; beta-Endorphin; Brain; Calcium; Corpus Striatum; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Frontal Lobe; Hippocampus; In Vitro Techniques; Peptide Fragments; Rats; Synaptosomes | 1985 |
Types of opioid receptors: relation to antinociception.
Topics: Animals; beta-Endorphin; Brain; Endorphins; Enkephalins; Guinea Pigs; In Vitro Techniques; Pain; Peptide Fragments; Protein Precursors; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1985 |
[Stress and the endogenous opioid system. II. Stress, stress models and endogenous opioid peptides].
Topics: Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalins; General Adaptation Syndrome; Humans; Peptides; Receptors, Opioid; Stress, Physiological | 1985 |
Opiate receptor-mediated chemotaxis of human monocytes.
Topics: beta-Endorphin; Chemotaxis; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Humans; In Vitro Techniques; Monocytes; Peptide Fragments; Receptors, Opioid | 1985 |
Stimulation by leumorphin of prolactin secretion from the pituitary in rats.
Topics: Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalins; Injections, Intraventricular; Male; Naloxone; Pituitary Gland, Anterior; Prolactin; Protein Precursors; Rats; Swine; Thyrotropin-Releasing Hormone | 1985 |
Generalization tests with intraventricularly applied pro-enkephalin B-derived peptides in rats trained to discriminate the opioid kappa receptor agonist ethylketocyclazocine.
Topics: Animals; beta-Endorphin; Cyclazocine; Discrimination Learning; Dynorphins; Endorphins; Enkephalins; Ethylketocyclazocine; Generalization, Stimulus; Injections, Intraventricular; Male; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
On the origin of Leu-enkephalin and Met-enkephalin in the rat neurohypophysis.
Topics: Animals; Arginine Vasopressin; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus, Middle; Male; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Sodium Glutamate | 1985 |
Release of immunoreactive Met-enkephalin from the spinal cord by intraventricular beta-endorphin but not morphine in anesthetized rats.
Topics: Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Peptide Fragments; Rats; Rats, Inbred Strains; Spinal Cord | 1985 |
Effects of dehydration on pro-dynorphin derived peptides in the neuro-intermediate lobe of the rat pituitary.
Topics: Animals; beta-Endorphin; Dehydration; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Food Deprivation; Hypothalamus; Male; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains | 1985 |
Selective presence of opiate receptors on intestinal circular muscle cells.
Topics: Acetylcholine; Animals; Atropine; Benzomorphans; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Guinea Pigs; Humans; Jejunum; Muscle Contraction; Muscle, Smooth; Naloxone; Peptide Fragments; Proglumide; Receptors, Opioid; Sincalide | 1985 |
Effects of opioid agonists and antagonists on oxytocin and vasopressin release in vitro.
Topics: Animals; Arginine Vasopressin; Benzomorphans; beta-Endorphin; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Male; Naloxone; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains | 1985 |
Antinociceptive profiles of opioid peptide agonists in a rat tooth pulp stimulation procedure.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; beta-Endorphin; Dental Pulp; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Pain; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains | 1985 |
Opioid-induced feeding: localization of sensitive brain sites.
Topics: Animals; beta-Endorphin; Brain Mapping; Corpus Striatum; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Feeding Behavior; Hypothalamus; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Stimulation, Chemical | 1986 |
RIA/chromatographic evidence for novel opioid peptide(s) in Squilla mantis ganglia.
Topics: Animals; beta-Endorphin; Brain; Chromatography, Gel; Decapoda; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Ganglia; Molecular Weight; Radioimmunoassay; Radioligand Assay; Rats; Receptors, Opioid | 1986 |
In vitro effects of endogenous opiate peptides on thyrotropin function: inhibition of thyrotropin-releasing hormone release and absence of effect on thyrotropin release.
Topics: alpha-Endorphin; Animals; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus; In Vitro Techniques; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone | 1986 |
Evidence for the presence of adrenocorticotropic and opiate-like hormones in the brains of two sea snakes, Hydrophis cyanocinctus and Lapemis hardwickii.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Biological Assay; Brain; Brain Chemistry; Corticosterone; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Female; Lipolysis; Male; Melanocyte-Stimulating Hormones; Snakes; Tissue Extracts | 1986 |
Opioids act centrally to modulate stress-induced decrease in luteinizing hormone in the rat.
Topics: Animals; beta-Endorphin; Corticotropin-Releasing Hormone; Dynorphins; Electroshock; Endorphins; Enkephalins; Immunologic Techniques; Luteinizing Hormone; Male; Rats; Receptors, Opioid; Stress, Physiological | 1986 |
Synaptosomal membrane-bound form of endopeptidase-24.15 generates Leu-enkephalin from dynorphin1-8, alpha- and beta-neoendorphin, and Met-enkephalin from Met-enkephalin-Arg6-Gly7-Leu8.
Topics: Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Endopeptidases; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Metalloendopeptidases; Peptide Fragments; Protease Inhibitors; Protein Precursors; Rats; Rats, Inbred Strains; Synaptic Membranes; Synaptosomes; Trypsin | 1987 |
[Frequency as the cardinal determinant for electroacupuncture analgesia to be reversed by opioid antagonists].
Topics: Acupuncture Therapy; Animals; beta-Endorphin; Dynorphins; Electric Stimulation Therapy; Endorphins; Enkephalins; Naloxone; Naltrexone; Pain; Rats; Sensory Thresholds; Transcutaneous Electric Nerve Stimulation | 1986 |
Activation of periaqueductal grey pools of beta-endorphin by analgetic electrical stimulation in freely moving rats.
Topics: Animals; beta-Endorphin; Dynorphins; Electric Stimulation Therapy; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Locomotion; Male; Periaqueductal Gray; Prolactin; Rats; Rats, Inbred Strains; Sensory Thresholds; Transcutaneous Electric Nerve Stimulation | 1987 |
Alterations in regional concentrations of endogenous opioids following traumatic brain injury in the cat.
Topics: Animals; beta-Endorphin; Blood Pressure; Brain Injuries; Cats; Dynorphins; Enkephalin, Leucine; Osmolar Concentration; Radioimmunoassay; Tissue Distribution | 1987 |
Mu-, delta-, kappa- and epsilon-opioid receptor modulation of the hypothalamic-pituitary-adrenocortical (HPA) axis: subchronic tolerance studies of endogenous opioid peptides.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; beta-Endorphin; Cerebral Ventricles; Drug Tolerance; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hypothalamo-Hypophyseal System; Male; Morphine; Naloxone; Pituitary-Adrenal System; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1987 |
Calmodulin content in rabbit reticulocyte and the influence of opioid peptides on calmodulin activity in its membrane.
Topics: Animals; beta-Endorphin; Calmodulin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Erythrocyte Membrane; Peptide Fragments; Rabbits; Reticulocytes | 1986 |
Combined high-performance liquid chromatographic-radioimmunoassay method for the analysis of endorphins, enkephalins and other neurotransmitter peptides.
Topics: beta-Endorphin; beta-Lipotropin; Buffers; Chromatography, High Pressure Liquid; Endorphins; Enkephalins; Humans; Indicators and Reagents; Neurotransmitter Agents; Radioimmunoassay; Spectrophotometry, Ultraviolet | 1987 |
The effect of opiates upon prostatic carcinoma cell growth.
Topics: beta-Endorphin; Cell Division; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Male; Morphine; Naloxone; Narcotics; Prostatic Neoplasms; Receptors, Opioid; Tumor Cells, Cultured | 1988 |
Effects of morphine and opioid peptides on plasma levels of atrial natriuretic peptide.
Topics: Animals; Atrial Natriuretic Factor; beta-Endorphin; Brain; Dynorphins; Endorphins; Enkephalin, Leucine; Epinephrine; Injections, Intraventricular; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains | 1988 |
Morphine increases the activity of midbrain dopamine neurons in vitro.
Topics: Animals; beta-Endorphin; Bicuculline; Dopamine; Endorphins; Enkephalin, Leucine; In Vitro Techniques; Male; Mesencephalon; Mice; Morphine; Neurons; Substantia Nigra | 1985 |
Differential alterations in opioid analgesia following neonatal monosodium glutamate treatment.
Topics: Analgesia; Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Brain Chemistry; Dose-Response Relationship, Drug; Electroshock; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Glutamates; Immunoenzyme Techniques; Nerve Degeneration; Rats; Rats, Inbred Strains; Reflex; Sodium Glutamate | 1985 |
Decreased plasma enkephalins in copper deficiency in man.
Topics: beta-Endorphin; Catecholamines; Ceruloplasmin; Copper; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Humans; Male; Superoxide Dismutase | 1986 |
Pharmacological evidence of a central effect of naltrexone, morphine, and beta-endorphin and a peripheral effect of met- and leu-enkephalin on retention of an inhibitory response in mice.
Topics: Adrenal Medulla; Animals; Avoidance Learning; beta-Endorphin; Brain; Drug Interactions; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Memory; Mice; Morphine; Naltrexone; Quaternary Ammonium Compounds; Retention, Psychology | 1985 |
Modulation by Leu-enkephalin of peptide release from perifused neurointermediate pituitary. II. Inhibition of calcium-mediated secretion of alpha-MSH and beta-endorphin.
Topics: Animals; beta-Endorphin; Calcimycin; Calcium; Colforsin; Corticotropin-Releasing Hormone; Endorphins; Enkephalin, Leucine; Isoproterenol; Male; Melanocyte-Stimulating Hormones; Pituitary Gland, Posterior; Potassium; Rats; Rats, Inbred Strains; Veratridine | 1986 |
Opioid-mediated cardiovascular effects of clonidine in spontaneously hypertensive rats: elimination by neonatal treatment with monosodium glutamate.
Topics: Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Enkephalin, Leucine; Glutamates; Heart Rate; Hemodynamics; Hypertension; Medulla Oblongata; Naloxone; Naltrexone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Glutamate | 1986 |
Selective potentiations in opioid analgesia following scopolamine pretreatment.
Topics: Animals; beta-Endorphin; Drug Synergism; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Morphine; Rats; Rats, Inbred Strains; Scopolamine | 1986 |
Release of immunoreactive met-enkephalin by intraventricular beta-endorphin in anesthetized rats.
Topics: Animals; beta-Endorphin; Brain; Brain Stem; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Kinetics; Male; Perfusion; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Distribution | 1986 |
The future role of neurosurgery in medicine.
Topics: Adrenal Medulla; beta-Endorphin; Cerebrovascular Disorders; Corpus Striatum; Electric Stimulation Therapy; Endorphins; Enkephalins; Forecasting; Humans; Microsurgery; Neurosurgery; Otosclerosis; Pain Management; Parkinson Disease; Serotonin; Stapes Mobilization; Stereotaxic Techniques | 1986 |
Altered beta-endorphin, Met- and Leu-enkephalins, and enkephalin-containing peptides in pancreas and pituitary of genetically obese diabetic (db/db) mice during development of diabetic syndrome.
Topics: Aging; Animals; beta-Endorphin; Body Weight; Diabetes Mellitus, Experimental; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Insulin; Islets of Langerhans; Mice; Mice, Obese; Pituitary Gland | 1986 |
[The significance of TRH, enkephalins and beta-endorphin in the central regulation of salivation].
Topics: Animals; Behavior, Animal; beta-Endorphin; Cats; Endorphins; Enkephalins; Injections, Intraventricular; Salivation; Thyrotropin-Releasing Hormone | 1985 |
Single and repeated electroconvulsive shock differentially affects the prodynorphin and pro-opiomelanocortin system in the rat.
Topics: Analgesia; Animals; beta-Endorphin; Brain Chemistry; Catalepsy; Electroconvulsive Therapy; Endorphins; Enkephalins; Male; Pituitary Gland; Pro-Opiomelanocortin; Protein Precursors; Rats; Rats, Inbred Strains; Spinal Cord; Time Factors | 1987 |
Differential effect of posttraining naloxone, beta-endorphin, leu-enkephalin and electroconvulsive shock administration upon memory of an open-field habituation and of a water-finding task.
Topics: Animals; beta-Endorphin; Drinking Behavior; Electroshock; Endorphins; Enkephalin, Leucine; Female; Habituation, Psychophysiologic; Hypothalamus; Memory; Naloxone; Rats; Rats, Inbred Strains; Water Deprivation | 1986 |
Opioid peptides in the regulation of TSH and prolactin secretion in the rat.
Topics: Animals; beta-Endorphin; Cold Temperature; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus; Injections, Intraventricular; Male; Prolactin; Rats; Rats, Inbred Strains; Thyrotropin | 1987 |
Involvement of endogenous opiates in glucose-stimulated hyperinsulinism of canine endotoxin shock. Inhibition by naloxone.
Topics: Animals; beta-Endorphin; Blood Glucose; Dogs; Endorphins; Endotoxins; Enkephalin, Leucine; Enkephalin, Methionine; Escherichia coli; Glucose; Hyperinsulinism; Insulin; Kinetics; Male; Naloxone; Shock, Septic | 1987 |
Central nervous system actions of beta-endorphin on gastric acid secretion.
Topics: Animals; Autonomic Nervous System; beta-Endorphin; Brain; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Gastric Acid; Injections, Intraventricular; Male; Naloxone; Pentagastrin; Vagus Nerve | 1987 |
Enkephalins in the rat pituitary gland: immunohistochemical and biochemical observations.
Topics: Animals; beta-Endorphin; Chromatography, Gel; Chromatography, High Pressure Liquid; Endorphins; Enkephalin, Methionine; Enkephalins; Fluorescent Antibody Technique; Histocytochemistry; Male; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Tissue Distribution | 1987 |
Role of endogenous opioids in soman (pinacolyl methylphosphonofluoridate)-induced antinociception.
Topics: Animals; beta-Endorphin; Corpus Striatum; Endopeptidases; Endorphins; Enkephalin, Leucine; Male; Mice; Neprilysin; Pain; Pituitary Gland; Rats; Rats, Inbred Strains; Soman | 1987 |
CSF beta-endorphin and leu-enkephalin levels in the acute and chronic stages of cerebral infarction.
Topics: Acute Disease; Aged; beta-Endorphin; Cerebral Infarction; Chronic Disease; Endorphins; Enkephalin, Leucine; Humans; Middle Aged; Radioimmunoassay | 1987 |
Modulation by endogenous opioid peptides of the secretion of LHRH from cockerel (Gallus domesticus) mediobasal hypothalamic tissue.
Topics: Animals; beta-Endorphin; Chickens; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Male; Naloxone | 1987 |
Beta-endorphin modulation of mitogen-stimulated calcium uptake by rat thymocytes.
Topics: Animals; beta-Endorphin; Calcium; Concanavalin A; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Male; Mitogens; Phytohemagglutinins; Rats; Rats, Inbred Strains; T-Lymphocytes | 1987 |
[Comparative effect of opioid receptor ligands on cell division in the epithelium of the tongue in white rats].
Topics: Animals; beta-Endorphin; Cell Division; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Naloxone; Rats; Tongue | 1987 |
The effect of enkephalins and of beta-endorphin on the hypertensive response to physostigmine in the rat.
Topics: Animals; beta-Endorphin; Blood Pressure; Catecholamines; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Male; Naloxone; Physostigmine; Rats; Rats, Inbred Strains | 1987 |
[Plasma leu-enkephalin and beta-endorphin changes in patients with painless myocardial ischemia].
Topics: beta-Endorphin; Coronary Disease; Enkephalin, Leucine; Female; Humans; Male; Middle Aged; Physical Exertion | 1987 |
[Role of opioid peptides in the neurotrophic control of the acetylcholine-sensitive membrane of rat skeletal muscle fibers].
Topics: Acetylcholine; Animals; beta-Endorphin; Diaphragm; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Muscle Denervation; Muscles; Rats; Synaptic Membranes | 1987 |
Analgesia in defeated mice: evidence for mediation via central rather than pituitary or adrenal endogenous opioid peptides.
Topics: Animals; beta-Endorphin; Central Nervous System; Dexamethasone; Endorphins; Enkephalins; Male; Mice; Pain; Pituitary-Adrenal System; Reserpine; Social Behavior; Stress, Psychological | 1988 |
Guanine nucleotide regulation of [125I]beta-endorphin binding to rat brain membranes: monovalent cation requirement.
Topics: Animals; beta-Endorphin; Brain; Cations, Monovalent; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Lithium; Male; Phenazocine; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride | 1988 |
The effects of corticotropin, opioid peptides and crude pituitary extract on the production of dehydroepiandrosterone and corticosterone by mature rat adrenal cells in tissue culture.
Topics: Adrenal Glands; Animals; beta-Endorphin; beta-Lipotropin; Cells, Cultured; Corticosterone; Cosyntropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enkephalins; Female; Hydrocortisone; Kinetics; Pituitary Gland; Rats; Rats, Inbred Strains; Tissue Extracts | 1988 |
Beta-endorphin-(1-27) antagonizes beta-endorphin- but not morphine-, D-Pen2-D-Pen5-enkephalin- and U50, 488H-induced analgesia in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Peptide Fragments; Pyrrolidines; Reaction Time | 1988 |
Interaction of endogenous opioids and developing T lymphocytes.
Topics: Animals; Antigens, Ly; beta-Endorphin; Enkephalins; Flow Cytometry; Mice; T-Lymphocytes | 1988 |
[The opiate system of the brain in patients with alopecia areata].
Topics: Adolescent; Adult; Alopecia Areata; beta-Endorphin; Brain; Chronic Disease; Endorphins; Enkephalin, Leucine; Female; Humans; Male; Middle Aged; Neurotensin | 1988 |
Possible delta receptor mediation of the effect of beta-endorphin on luteinizing hormone (LH) release, but not on prolactin (PRL) release, in the ovariectomized rat.
Topics: Animals; beta-Endorphin; Castration; Endorphins; Enkephalin, Leucine; Female; Kinetics; Luteinizing Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Opioid effects on plasma concentrations of luteinizing hormone and prolactin in the adult male rhesus monkey.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Macaca mulatta; Male; Morphine; Naloxone; Prolactin; Receptors, Opioid | 1985 |
[Effect of beta-neo-endorphin--an agonist of chi-opiate receptors on the neuronal activity of the cerebral cortex].
Topics: Animals; beta-Endorphin; Cats; Cerebral Cortex; Electric Stimulation; Endorphins; Enkephalin, Leucine; Evoked Potentials; Female; Iontophoresis; Male; Morphine; Neurons; Receptors, Opioid | 1985 |
Opiate receptor binding profile in the rabbit cerebellum and brain membranes.
Topics: Animals; beta-Endorphin; Binding Sites; Binding, Competitive; Brain; Cerebellum; Cold Temperature; Cyclazocine; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Male; Rabbits; Receptors, Opioid; Sodium; Tritium | 1985 |
Beta-endorphin does not protect alkylation of opiate receptor by N-ethylmaleimide.
Topics: Alkylation; Animals; beta-Endorphin; Brain Chemistry; Detergents; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylmaleimide; In Vitro Techniques; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Central delta-opioid receptor interactions and the inhibition of reflex urinary bladder contractions in the rat.
Topics: Animals; beta-Endorphin; Central Nervous System; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalins; Female; Injections, Intraventricular; Injections, Spinal; Muscle Contraction; Naloxone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Urinary Bladder | 1985 |
beta-Endorphin and enkephalins stimulate duodenal mucosal alkaline secretion in the rat in vivo.
Topics: Animals; beta-Endorphin; Bicarbonates; Duodenum; Endorphins; Enkephalins; Intestinal Mucosa; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Stimulation, Chemical | 1986 |
Centrally administered beta-endorphin produces prolonged changes in delta-opioid ligand activity in vivo.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Female; Injections, Intraventricular; Muscle Contraction; Muscle, Smooth; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Urinary Bladder | 1986 |
Behavioral specificity of beta-endorphin suppression of sexual behavior: differential receptor antagonism.
Topics: Animals; Behavior, Animal; beta-Endorphin; Endorphins; Enkephalin, Leucine; Estrogens; Female; Naloxone; Narcotic Antagonists; Ovariectomy; Progesterone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sexual Behavior, Animal | 1986 |
The in vitro and in vivo effects of enkephalins and beta-endorphin on ACE activity in mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; beta-Endorphin; Brain; Drug Interactions; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; In Vitro Techniques; Lung; Mice; Mice, Inbred Strains; Naloxone; Peptidyl-Dipeptidase A | 1986 |
Mu receptors at discrete hypothalamic and brainstem sites mediate opioid peptide-induced increases in central sympathetic outflow.
Topics: Animals; beta-Endorphin; Brain Stem; Catecholamines; Cerebral Cortex; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Sympathetic Nervous System; Trigeminal Nucleus, Spinal | 1986 |
Behavioral effects of opioid peptides selective for mu or delta receptors. I. Morphine-like discriminative stimulus effects.
Topics: Animals; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Discrimination Learning; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1986 |
Behavioral effects of opioid peptides selective for mu or delta receptors. II. Locomotor activity in nondependent and morphine-dependent rats.
Topics: Animals; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Morphine Dependence; Motor Activity; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1986 |
A correlation analysis of the regional distribution of central enkephalin and beta-endorphin immunoreactive terminals and of opiate receptors in adult and old male rats. Evidence for the existence of two main types of communication in the central nervous
Topics: Age Factors; Animals; Autoradiography; beta-Endorphin; Brain; Endorphins; Enkephalins; Fluorescent Antibody Technique; Male; Nerve Endings; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Synaptic Transmission | 1986 |
[Effect of the opiate antagonist naloxone on the electrical activity of identified neurons in the edible snail].
Topics: Animals; Benzomorphans; beta-Endorphin; Drug Interactions; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Helix, Snails; Membrane Potentials; Morphine; Naloxone; Neurons; Receptors, Opioid | 1987 |
Subunit structure and purification of opioid receptors.
Topics: Animals; beta-Endorphin; Cattle; Corpus Striatum; Endorphins; Enkephalins; Glycoproteins; History, 20th Century; Membrane Proteins; Molecular Weight; Protein Conformation; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Wheat Germ Agglutinins | 1987 |
Altered neuropeptide concentrations in spontaneously hypertensive rats: cause or consequence?
Topics: Animals; Arginine Vasopressin; beta-Endorphin; Brain; Clonidine; Endorphins; Enkephalin, Leucine; Hypertension; Male; Nerve Tissue Proteins; Oxytocin; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1985 |
Protease inhibition increases the analgesic potency of peptide E.
Topics: Analgesics; Animals; Bacitracin; beta-Endorphin; Drug Synergism; Endorphins; Enkephalins; Injections, Intraventricular; Leucine; Male; Mice; Peptides; Protease Inhibitors | 1985 |
Senescent change in tissue weight and immunoreactive beta-endorphin, enkephalin, and vasopressin in eight regions of C57BL/6J mouse brain and pituitary.
Topics: Aging; Animals; beta-Endorphin; Brain Chemistry; Brain Stem; Cerebral Cortex; Corpus Striatum; Endorphins; Enkephalins; Hippocampus; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Organ Size; Pituitary Gland; Vasopressins | 1985 |
Secondary neuroendocrine carcinomas of the skin. An immunohistochemical comparison with primary neuroendocrine carcinoma of the skin ("Merkel cell" carcinoma).
Topics: Adult; Aged; beta-Endorphin; Bombesin; Carcinoid Tumor; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Phosphopyruvate Hydratase; Skin; Skin Neoplasms | 1985 |
Biotransformation of neuropeptides.
Topics: beta-Endorphin; Cholecystokinin; Dynorphins; Endorphins; Enkephalins; Gonadotropin-Releasing Hormone; Nerve Tissue Proteins; Neurotensin; Oxytocin; Somatostatin; Substance P; Thyrotropin-Releasing Hormone; Vasopressins | 1984 |
Characterization and immunocytochemical application of monoclonal antibodies against enkephalins.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; beta-Endorphin; Brain Chemistry; Brain Stem; Cross Reactions; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Radioimmunoassay; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1984 |
Distribution of pro-opiomelanocortin-derived peptides and enkephalins in the rat central nucleus of the amygdala.
Topics: Amygdala; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Brain Mapping; Endorphins; Enkephalins; Melanocyte-Stimulating Hormones; Nerve Tissue Proteins; Neural Pathways; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors; Rats | 1984 |
Release of opioid peptides in canine hemorrhagic hypotension: effects of naloxone.
Topics: Adrenal Glands; Animals; beta-Endorphin; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Hemorrhage; Hypotension; Male; Naloxone | 1984 |
Lack of response in the release of oxytocin and vasopressin from isolated neurohypophyses to dopamine, met-enkephalin and leu-enkephalin.
Topics: Animals; Arginine Vasopressin; beta-Endorphin; Dopamine; Drug Interactions; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Ouabain; Oxytocin; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains | 1984 |
Inhibition of the cardiac response to sympathetic nerve stimulation by opioid peptides and its potentiation by morphine and methadone.
Topics: Animals; beta-Endorphin; Drug Synergism; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Guinea Pigs; Heart; In Vitro Techniques; Male; Methadone; Morphine; Myocardial Contraction; Norepinephrine; Sympathetic Nervous System | 1984 |
The role of endogenous opioid peptides in control of the menstrual cycle.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalins; Female; Gonadotropins, Pituitary; Haplorhini; Humans; Hypothalamus; Menstrual Cycle; Pituitary Hormone-Releasing Hormones | 1984 |
Involvement of endogenous opioid systems in social behavior of individually-housed mice.
Topics: Aggression; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Humans; Male; Methadone; Mice; Mice, Inbred DBA; Morphine; Motor Activity; Naloxone; Receptors, Opioid; Social Behavior; Social Isolation | 1984 |
[Opioid peptide content of the brain and blood of rats under immobilization stress].
Topics: Animals; beta-Endorphin; Brain Chemistry; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Recurrence; Restraint, Physical; Stress, Physiological; Time Factors | 1984 |
[Effect of beta-endorphin, enkephalins and their synthetic analogs on the neuronal electrical activity of the respiratory center in the medulla oblongata].
Topics: Animals; beta-Endorphin; Cats; Endorphins; Enkephalins; Iontophoresis; Medulla Oblongata; Microelectrodes; Morphine; Naloxone; Neurons; Rabbits; Respiration; Respiratory Center | 1984 |
Neuroendocrinologic developments in sexuality: beta-endorphins in sexual desire phase disorders.
Topics: beta-Endorphin; Endorphins; Enkephalins; Female; Gonadotropin-Releasing Hormone; Humans; Male; Sexual Dysfunctions, Psychological | 1984 |
[Differences in the action of enkephalins, beta-endorphin, and morphine on spontaneous rhythmic movements of the isolated rabbit ileum].
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Gastrointestinal Motility; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Naloxone; Rabbits; Receptors, Opioid | 1984 |
[Endogenous opioid peptide level of patients with borderline arterial hypertension].
Topics: Adolescent; Adult; beta-Endorphin; Blood Pressure; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Hypertension; Male; Physical Exertion; Veins | 1984 |
Beta-endorphin. Binding activity of synthetic analogs with various chain lengths in neuroblastoma x glioma NG108-15 cell membranes.
Topics: Animals; beta-Endorphin; Cell Membrane; Endorphins; Enkephalin, Leucine; Glioma; In Vitro Techniques; Kinetics; Neuroblastoma; Rats; Receptors, Opioid; Structure-Activity Relationship | 1984 |
Application of receptor theory provides further evidence for the existence of the epsilon-opioid receptor in rat vas deferens.
Topics: Animals; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Vas Deferens | 1984 |
Opiate activity of peptides derived from the three opioid peptide families on the rat vas deferens.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalins; In Vitro Techniques; Male; Pro-Opiomelanocortin; Protein Precursors; Rats; Receptors, Opioid; Vas Deferens | 1984 |
Hypothalamic opioid peptide regulation of catecholamine secretion.
Topics: Animals; beta-Endorphin; Brain; Catecholamines; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Morphine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Tissue concentrations of opioid peptides in rats do not depend on blood pressure height.
Topics: Adrenal Glands; Animals; beta-Endorphin; Blood Pressure; Central Nervous System; Endorphins; Enkephalin, Leucine; Hypertension; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1984 |
Increased beta-endorphin but not met-enkephalin levels in human cerebrospinal fluid after acupuncture for recurrent pain.
Topics: Acupuncture Therapy; Adult; Aged; beta-Endorphin; Chromatography, Ion Exchange; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Humans; Male; Middle Aged; Pain Management; Radioimmunoassay; Recurrence | 1980 |
Effects of beta-endorphin, met-enkephalin and somatostatin on the neurotensin-induced neurogenic contraction in the guinea-pig ileum.
Topics: Animals; Atropine; beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Neurotensin; Somatostatin | 1981 |
Immunohistochemical localisation of substances reactive to antisera against alpha- and beta-endorphin and met-enkephalin in the brain of Rana temporaria L.
Topics: alpha-Endorphin; Animals; beta-Endorphin; Brain Chemistry; Endorphins; Enkephalin, Methionine; Enkephalins; Fluorescent Antibody Technique; Paraventricular Hypothalamic Nucleus; Pituitary Gland, Anterior; Preoptic Area; Rana temporaria; Tuber Cinereum | 1981 |
Possible regulatory role of dynorphin on morphine- and beta-endorphin-induced analgesia.
Topics: Analgesics; Animals; beta-Endorphin; Drug Interactions; Drug Tolerance; Dynorphins; Endorphins; Enkephalins; Humans; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Substance Withdrawal Syndrome | 1981 |
Involvement of alpha-adrenergic mechanisms in growth hormone release induced by opioid peptides in conscious rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; beta-Endorphin; Clonidine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Ditiocarb; Endorphins; Enkephalins; Growth Hormone; Hormones; Male; Rats; Rats, Inbred Strains; Reserpine | 1981 |
Hypothalamic substances in the control of body temperature: general characteristics.
Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; beta-Endorphin; Body Temperature Regulation; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Histamine; Humans; Hypothalamus; Melanocyte-Stimulating Hormones; Neurotransmitter Agents; Peptides; Receptors, Opioid; Taurine | 1981 |
Evidence for a single opioid receptor type on the field stimulated rat vas deferens.
Topics: Animals; Benzimidazoles; beta-Endorphin; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalins; Etorphine; Fentanyl; Male; Morphine; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sufentanil; Vas Deferens | 1981 |
Effects of neuroleptic drugs on endogenous opioid peptides in the rat.
Topics: Animals; Antipsychotic Agents; beta-Endorphin; Brain; Dynorphins; Endorphins; Enkephalin, Methionine; Enkephalins; Haloperidol; Pituitary Gland; Rats; Receptors, Dopamine; Receptors, Opioid; Synaptic Transmission | 1981 |
Opiate peptides modulate somatostatin release from dispersed hypothalamic cells.
Topics: Animals; beta-Endorphin; Cold Temperature; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Hypothalamus; In Vitro Techniques; Male; Naloxone; Rats; Rats, Inbred Strains; Somatostatin | 1981 |
Isoelectric point determination of human and camel beta-endorphin, alpha-endorphin and enkephalins.
Topics: alpha-Endorphin; Animals; beta-Endorphin; Camelus; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Pituitary Gland; Rats; Rats, Inbred Strains; Species Specificity | 1982 |
Studies on the structural prerequisites for the activation of the beta-endorphin receptor on the rat vas deferens.
Topics: Animals; beta-Endorphin; Drug Interactions; Dynorphins; Electric Stimulation; Endorphins; Enkephalins; In Vitro Techniques; Male; Muscle, Smooth; Narcotics; Rats; Receptors, Opioid; Vas Deferens | 1982 |
Opioid peptides have found their roots.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Chemical Phenomena; Chemistry; Dynorphins; Endorphins; Enkephalins; Protein Precursors; Swine | 1982 |
Cloning and sequence analysis of cDNA for porcine beta-neo-endorphin/dynorphin precursor.
Topics: Amino Acid Sequence; Animals; Base Sequence; beta-Endorphin; Cattle; Cloning, Molecular; DNA; DNA Restriction Enzymes; DNA, Recombinant; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Hypothalamus; Protein Precursors; RNA, Messenger; Swine | 1982 |
Stimulation of prolactin secretion in the rat by alpha-neo-endorphin, beta-neo-endorphin and dynorphin.
Topics: Animals; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalins; Gonadotropin-Releasing Hormone; Injections, Intraventricular; Male; Naloxone; Pituitary Gland; Prolactin; Protein Precursors; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1982 |
Dynorphin-immunoreactive neurons in the central nervous system of the rat.
Topics: Animals; beta-Endorphin; Central Nervous System; Dynorphins; Endorphins; Enkephalins; Fluorescent Antibody Technique; Male; Rats; Rats, Inbred Strains | 1982 |
Characterization of electrophoretically separable endorphins in human CSF.
Topics: beta-Endorphin; Chromatography, High Pressure Liquid; Dynorphins; Electrophoresis, Agar Gel; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Radioimmunoassay | 1983 |
Opiate analgesics and endorphins inhibit rat dorsal root potential in vitro.
Topics: alpha-Endorphin; Analgesics, Opioid; Animals; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; In Vitro Techniques; Rats; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1980 |
Differential modification of opiate receptor activity by arylsulfatase treatment.
Topics: Analgesia; Analgesics, Opioid; Animals; Arylsulfatases; beta-Endorphin; Cyclazocine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Antagonism; Endorphins; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hormones; Kinetics; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Receptors, Opioid; Sulfatases | 1983 |
Effect of prenatal alcohol exposure on amine and peptide neurotransmitter systems.
Topics: Animals; beta-Endorphin; Brain Chemistry; Disease Models, Animal; Dopamine; Endorphins; Enkephalin, Leucine; Female; Fetal Alcohol Spectrum Disorders; Neurotransmitter Agents; Norepinephrine; Pregnancy; Rats; Rats, Inbred Strains; Serotonin | 1983 |
Regional distribution of dynorphin and neo-endorphin peptides in rat brain, spinal cord, and pituitary.
Topics: Animals; beta-Endorphin; Brain Chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Immune Sera; Male; Peptide Fragments; Peptides; Pituitary Gland; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Distribution | 1983 |
Plasma immunoreactive beta-endorphin and enkephalin concentration in healthy subjects before and after electroacupuncture.
Topics: Acupuncture Therapy; Adrenocorticotropic Hormone; Adult; beta-Endorphin; Electric Stimulation Therapy; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Male; Naloxone; Radioimmunoassay | 1983 |
In vitro study of frog (Rana ridibunda Pallas) neurointermediate lobe secretion by use of a simplified perifusion system. III. Effect of neuropeptides on alpha-MSH secretion.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; In Vitro Techniques; Male; Melanocyte-Stimulating Hormones; Morphine; Perfusion; Pituitary Gland; Rana ridibunda; Somatostatin; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1983 |
Evidence for a selective processing of proenkephalin B into different opioid peptide forms in particular regions of rat brain and pituitary.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Molecular Weight; Organ Specificity; Peptide Fragments; Pituitary Gland; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
Proenkephalin B (prodynorphin)-derived opioid peptides: evidence for a differential processing in lobes of the pituitary.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Molecular Weight; Peptide Fragments; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Dynorphin-(1-13) restores the potency of morphine on the tolerant guinea pig ileum.
Topics: Animals; beta-Endorphin; Cyclazocine; Drug Interactions; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Peptide Fragments | 1984 |
Benzomorphan sites are ligand recognition sites of putative epsilon-receptors.
Topics: Animals; Benzomorphans; beta-Endorphin; Binding, Competitive; Brain; Cell Membrane; Diprenorphine; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Guinea Pigs; Humans; Kinetics; Morphinans; Peptide Fragments; Placenta; Pregnancy; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Differential effects of various opioid peptides on vasopressin and oxytocin release from the rat pituitary in vitro.
Topics: Animals; beta-Endorphin; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Leucine; Female; In Vitro Techniques; Naloxone; Oxytocin; Pituitary Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Vasopressins | 1984 |
Neuropeptides and monoaminergic neurotransmitters: their relation to pain.
Topics: Analgesia; Angiotensin II; beta-Endorphin; Cholecystokinin; Endorphins; Enkephalins; Humans; Neurotensin; Neurotransmitter Agents; Pain; Peptides; Somatostatin; Substance P | 1980 |
Effects of beta-endorphin, vasoactive intestinal polypeptide and cholecystokinin octapeptide on cat carotid chemoreceptor activity.
Topics: Animals; beta-Endorphin; Carotid Body; Cats; Cholecystokinin; Endorphins; Enkephalin, Methionine; Enkephalins; Gastrointestinal Hormones; Naloxone; Sincalide; Substance P; Vasoactive Intestinal Peptide | 1981 |
Contractile effect of morphine and related opioid alkaloids, beta-endorphin and methionine enkephalin on the isolated colon from Long Evans rats.
Topics: Animals; beta-Endorphin; Calcium; Colon; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Hexamethonium Compounds; Histamine Release; Humans; In Vitro Techniques; Male; Morphine; Muscle Contraction; Naloxone; Narcotics; Opioid-Related Disorders; Rats; Rats, Inbred Strains; Tetrodotoxin | 1981 |
Rapid separation of enkephalins and endorphins on Sep-Pak reverse phase cartridges.
Topics: alpha-Endorphin; beta-Endorphin; Chromatography; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; gamma-Endorphin | 1981 |
Age-related changes in central nervous system enkephalins and substance P.
Topics: Aging; Animals; beta-Endorphin; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Hypothalamus; Male; Rats; Rats, Inbred Strains; Substance P | 1981 |
Regional distribution of alpha- and gamma-type endorphins in rat brain.
Topics: alpha-Endorphin; Animals; beta-Endorphin; Brain Chemistry; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Endorphin; Male; Rats; Tissue Distribution | 1982 |
Analgesic activity of substance P in rats: apparent mediation by met-enkephalin release.
Topics: Analgesia; Animals; Bacitracin; beta-Endorphin; Cerebral Ventricles; Endorphins; Enkephalin, Methionine; Enkephalins; Immunologic Techniques; Male; Naloxone; Protease Inhibitors; Rats; Substance P; Vocalization, Animal | 1982 |
Enkephalin- and substance P-like immunoreactivities of mammalian sperm and accessory sex glands.
Topics: Acetylcholine; Animals; beta-Endorphin; Cattle; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Humans; Male; Prostate; Rabbits; Radioimmunoassay; Seminal Vesicles; Species Specificity; Spermatozoa; Substance P | 1982 |
Transmitter sensitivities in oval neurons from rat brainstem cultures.
Topics: Animals; beta-Endorphin; Brain Stem; Cells, Cultured; Electric Conductivity; Embryo, Mammalian; Endorphins; Enkephalins; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Neurons; Neurotransmitter Agents; Rats; Substance P | 1983 |
Endorphins stimulate normal human peripheral blood lymphocyte natural killer activity.
Topics: alpha-Endorphin; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; gamma-Endorphin; Humans; Interferons; Killer Cells, Natural; Morphine; Naloxone | 1984 |
Peptides and nociception.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Bombesin; Bradykinin; Cholecystokinin; Dynorphins; Endorphins; Enkephalins; Melanocyte-Stimulating Hormones; Mice; Nervous System; Neurotensin; Pain; Peptide Fragments; Peptides; Rats; Somatostatin; Substance P; Thyrotropin-Releasing Hormone; Vasopressins | 1984 |
Rapid development of tolerance to the hyperthermic effect of beta-endorphin, and cross-tolerance between the enkephalins and beta-endorphin.
Topics: Animals; beta-Endorphin; Body Temperature; Drug Tolerance; Endorphins; Enkephalins; Humans; Mice; Mice, Inbred ICR; Naloxone; Temperature; Time Factors | 1980 |
Central inhibition of basal pancreatic and gastric secretions by beta-endorphin in rats.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalins; Gastric Juice; Gastrointestinal Motility; Male; Morphine; Naloxone; Pancreatic Juice; Rats | 1980 |
Morphine and opioid peptides reduce paraventricular neuronal activity: studies on the rat hypothalamic slice preparation.
Topics: Animals; beta-Endorphin; Depression, Chemical; Endorphins; Enkephalin, Methionine; Enkephalins; Hypothalamus; In Vitro Techniques; Male; Morphine; Naloxone; Neurons; Paraventricular Hypothalamic Nucleus; Rats | 1980 |
Heterogeneity of endogeneous opiates: H-endorphin is not correlated with enkephalin or with beta-endorphin.
Topics: Animals; beta-Endorphin; Brain Chemistry; Endorphins; Enkephalin, Leucine; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Rats | 1980 |
Altered levels of beta-endorphin fragments after chronic morphine treatment of guinea-pig ileum in vitro and in vivo.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Drug Tolerance; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Peptide Fragments; Radioimmunoassay | 1980 |
Stress-induced release of brain and pituitary beta-endorphin: major role of endorphins in generation of hyperthermia, not analgesia.
Topics: Animals; beta-Endorphin; Body Temperature Regulation; Electroshock; Endorphins; Enkephalin, Methionine; Enkephalins; Hypothalamus; Male; Morphine; Naloxone; Nociceptors; Pituitary Gland; Rats; Stress, Physiological | 1981 |
A study of 24-hour profiles of plasma met-enkephalin in man.
Topics: Adrenocorticotropic Hormone; Adult; beta-Endorphin; beta-Lipotropin; Circadian Rhythm; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Humans; Hydrocortisone; Male | 1981 |
Central effects of morphine, levorphanol, (-)-methadone and the opioid-like peptides beta-endorphin and D-alanine2- methionine enkephalinamide on urine volume outflow and electrolytes.
Topics: Animals; beta-Endorphin; Brain; Diuresis; Electrolytes; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Levorphanol; Male; Methadone; Morphine; Naloxone; Narcotics; Rats; Vasopressins | 1981 |
Sex differences in the content of beta-endorphin and enkephalin-like peptides in the pituitary of obese (ob/ob) mice.
Topics: Animals; beta-Endorphin; beta-Lipotropin; Chromatography, Gel; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Male; Mice; Mice, Obese; Pituitary Gland; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors; Radioimmunoassay; Sex Factors | 1981 |
Comparative study on the effect of morphine and the opioid-like peptides in the vas deferens of rodents: species and strain differences, evidence for multiple opiate receptors.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Derivatives; Peptides; Rats; Receptors, Opioid; Species Specificity; Vas Deferens | 1981 |
An iontophoretic survey of opioid peptide actions in the rat limbic system: in search of opiate epileptogenic mechanisms.
Topics: Action Potentials; Amygdala; Animals; beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Gyrus Cinguli; Hippocampus; Iontophoresis; Limbic System; Male; Morphine; Neurons; Pressure; Rats; Seizures; Septal Nuclei | 1980 |
Effects of opioid peptides on synaptic potentials in explants of rat hippocampus.
Topics: Action Potentials; Animals; beta-Endorphin; Culture Techniques; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalins; Hippocampus; Rats | 1981 |
[Binding of a tritiated enkephalinergic analog (FK 33-824) to a mitochondrial fraction of rat brain].
Topics: Animals; beta-Endorphin; Brain; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalins; Kinetics; Levallorphan; Mitochondria; Morphine; Papio; Rats | 1981 |
A reaction of acetaldehyde with enkephalins and related peptides.
Topics: Acetaldehyde; Animals; beta-Endorphin; Brain; Chemical Phenomena; Chemistry; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Rats | 1981 |
Brain opiates and corticotrophin-related peptides. The Goulstonian Lecture 1980.
Topics: Acupuncture Therapy; Adrenocorticotropic Hormone; beta-Endorphin; beta-Lipotropin; Brain Chemistry; Endorphins; Enkephalin, Methionine; Enkephalins; Humans; Melanocyte-Stimulating Hormones; Neoplasms; Radioimmunoassay | 1981 |
Effects of centrally administered endogenous opioid peptides on drinking behavior, increased plasma vasopressin concentration and pressor response to hypertonic sodium chloride.
Topics: Animals; beta-Endorphin; Blood Pressure; Drinking Behavior; Endorphins; Enkephalin, Leucine; Enkephalins; Feeding Behavior; Kinetics; Male; Naloxone; Polyethylene Glycols; Rats; Sodium Chloride; Vasopressins | 1981 |
[Sensitivity of neurons in different regions of the brain to met-enkephalin, beta-endorphin, and thyroliberin in the rat].
Topics: Animals; beta-Endorphin; Brain; Cerebral Cortex; Drug Interactions; Endorphins; Enkephalin, Methionine; Enkephalins; Hippocampus; Male; Nalorphine; Rats; Septum Pellucidum; Thalamus; Thyrotropin-Releasing Hormone | 1981 |
Comparison of the anticonvulsant effects of opioid peptides and etorphine in rats after icv administration.
Topics: Animals; Anticonvulsants; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Etorphine; Flurothyl; Male; Morphinans; Naloxone; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1981 |
Plasma norepinephrine, epinephrine and dopamine responses to intracerebral administration of a met-enkephalin analog, D-ala2-met-enkephalinamide, in rats.
Topics: Animals; beta-Endorphin; Cisterna Magna; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Epinephrine; Injections; Injections, Intra-Arterial; Male; Naloxone; Norepinephrine; Rats; Rats, Inbred Strains | 1981 |
Detection from rat pituitary of beta-lipotropin and materials containing opiatelike activity by combined enzymatic radioreceptor assay.
Topics: Animals; beta-Endorphin; beta-Lipotropin; Endorphins; Enkephalin, Methionine; Enkephalins; Hydrogen-Ion Concentration; Pituitary Gland; Radioligand Assay; Rats; Time Factors | 1981 |
Effects of opioid peptides on thermoregulation.
Topics: Animals; beta-Endorphin; Body Temperature Regulation; Cats; Cattle; Endorphins; Enkephalin, Methionine; Enkephalins; Mice; Naloxone; Naltrexone; Narcotics; Rats; Structure-Activity Relationship | 1981 |
Comparison of analgesic and body temperature responses to intrathecal beta-endorphin and D-Ala2-D-Leu5-enkephalin.
Topics: Analgesics; Animals; beta-Endorphin; Body Temperature; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Spinal; Male; Rats; Rats, Inbred Strains; Reaction Time; Time Factors | 1981 |
Intracerebroventricular beta-endorphin increases food intake of rats.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Feeding Behavior; Injections, Intraperitoneal; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains | 1981 |
Increase of beta-endorphin in cerebrospinal fluid after removal of ACTH-secreting pituitary adenoma.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Humans; Hypophysectomy; Male; Middle Aged; Pain, Intractable; Pituitary Neoplasms | 1981 |
The effects of a met-enkephalin analogue on ACTH, beta-LPH, beta-endorphin and MET-enkephalin in patients with adrenocortical disease.
Topics: Addison Disease; Adrenalectomy; Adrenocorticotropic Hormone; Adult; beta-Endorphin; beta-Lipotropin; Cushing Syndrome; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Hormones; Humans; Male; Middle Aged; Naloxone | 1981 |
Studies on circulating met-enkephalin and beta-endorphin: normal subjects and patients with renal and adrenal disease.
Topics: Addison Disease; Adrenalectomy; Adrenocorticotropic Hormone; beta-Endorphin; beta-Lipotropin; Cushing Syndrome; Dexamethasone; Endorphins; Enkephalin, Methionine; Enkephalins; Humans; Hydrocortisone; Insulin; Kidney Failure, Chronic; Male | 1981 |
Beta-endorphin. Vasodilating effect on the microcirculatory system of hamster cheek pouch.
Topics: Animals; beta-Endorphin; Cheek; Cricetinae; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Male; Microcirculation; Morphine; Vasodilation | 1981 |
Opiate receptor-binding activity of [D-Thr2,Thz5]-and [D-Met2,Thz5]-enkephalinamides.
Topics: Animals; beta-Endorphin; Brain Chemistry; Cell Membrane; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalins; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Thiazolidines | 1981 |
A quantitative analysis of the shaking behavior induced in rats by beta-endorphin and [D-Ala2, Met5]enkephalinamide.
Topics: Animals; Behavior, Animal; beta-Endorphin; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains | 1982 |
Further characterization of opioid receptors in the striatum mediating muscular rigidity in rats.
Topics: Animals; beta-Endorphin; Caseins; Caudate Nucleus; Electromyography; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Haloperidol; Male; Morphine; Muscle Rigidity; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid | 1981 |
Levels of dynorphin-(1-13) immunoreactivity in rat neurointermediate pituitaries are concomitantly altered with those of leucine enkephalin and vasopressin in response to various endocrine manipulations.
Topics: Adrenalectomy; Animals; beta-Endorphin; Dehydration; Dexamethasone; Diabetes Insipidus; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Peptide Fragments; Pituitary Gland; Rats; Rats, Inbred Strains; Sodium Chloride; Vasopressins | 1981 |
Intracerebroventricular administration of nanogram amounts of beta-endorphin and Met-enkephalin causes retrograde amnesia in rats.
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Humans; Injections, Intraventricular; Rats; Rats, Inbred Strains | 1982 |
Calcium-opiate antagonism in the periaqueductal grey (PGA) region.
Topics: Animals; beta-Endorphin; Calcium; Cerebral Aqueduct; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Morphine; Nociceptors; Rats; Rats, Inbred Strains | 1981 |
Evidence that inhibition of nicotine-mediated catecholamine secretion from adrenal chromaffin cells by enkephalin, beta-endorphin, dynorphin (1-13), and opiates is not mediated via specific opiate receptors.
Topics: Adrenal Glands; Animals; beta-Endorphin; Cattle; Chromaffin Granules; Chromaffin System; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Kinetics; Morphine; Narcotics; Nicotine; Norepinephrine; Peptide Fragments; Structure-Activity Relationship | 1982 |
Role of endorphins in addiction.
Topics: Alcoholism; Animals; beta-Endorphin; Brain; Corpus Striatum; Endorphins; Enkephalins; Heroin Dependence; Humans; Morphine Dependence; Opioid-Related Disorders; Pituitary Gland; Rats; Receptors, Opioid | 1981 |
Endorphin studies: electrophysiologic effects.
Topics: Animals; beta-Endorphin; Brain; Brain Mapping; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Interneurons; Kindling, Neurologic; Neural Inhibition; Neurons; Pituitary Gland; Rats; Receptors, Opioid; Seizures | 1981 |
Stress and endogenous opioid peptides: a review.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; beta-Endorphin; Body Temperature Regulation; Brain; Electroshock; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Humans; Nociceptors; Pituitary Gland; Rats; Receptors, Opioid; Sensory Thresholds; Stress, Physiological | 1981 |
Possible regulatory role of dynorphin-(1-13) on narcotic-induced changes in naloxone efficacy.
Topics: Analgesia; Analgesics; Animals; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Mice; Morphine; Naloxone; Peptide Fragments; Receptors, Opioid | 1981 |
Differences in central effects of beta-endorphin and enkephalins: beta-endorphin. A potent psychomotor stimulant.
Topics: Akathisia, Drug-Induced; Animals; beta-Endorphin; Cats; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Humans; Male; Nalorphine; Receptors, Opioid; Vomiting | 1982 |
Elevation of Met5-enkephalin and beta-endorphin hypothalamic content in rats receiving anorectic drugs: differences between D-fenfluramine and D-amphetamine.
Topics: Animals; beta-Endorphin; Body Weight; Brain; Dextroamphetamine; Endorphins; Enkephalin, Methionine; Enkephalins; Fenfluramine; Hypothalamus; Male; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors | 1982 |
beta-Endorphin: demonstration of a tertiary structure in aqueous solution.
Topics: beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Hydrogen-Ion Concentration; Peptide Fragments; Protein Conformation; Spectrophotometry, Ultraviolet | 1981 |
Effects of a synthetic Met5-enkephalin analog on plasma luteinizing hormone and prolactin levels in conscious orchiectomized rats.
Topics: 5,6-Dihydroxytryptamine; Animals; beta-Endorphin; Castration; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalins; Fenclonine; Humans; Luteinizing Hormone; Male; Naloxone; Pimozide; Prolactin; Rats; Rats, Inbred Strains | 1982 |
[Sensitivity of hypothalamic neurons to beta-endomorphin, met-enkephalin, and thyroliberin].
Topics: Animals; beta-Endorphin; Depression, Chemical; Electrophysiology; Endorphins; Enkephalin, Methionine; Enkephalins; Hypothalamus; Male; Naloxone; Rats; Stimulation, Chemical; Thyrotropin-Releasing Hormone | 1982 |
Distribution of radioactivity in the spinal cord after intracerebroventricular and intravenous injection of radiolabeled opioid peptides in mice.
Topics: Analgesics; Animals; beta-Endorphin; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Muscles; Spinal Cord | 1982 |
Mu and delta receptors: their role in analgesia in the differential effects of opioid peptides on analgesia.
Topics: Animals; Behavior, Animal; beta-Endorphin; Brain; Endorphins; Enkephalins; Kinetics; Male; Mice; Models, Biological; Morphine; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship | 1982 |
The choice of opiate receptor subtype by neo-endorphins.
Topics: Animals; Benzomorphans; beta-Endorphin; Cyclazocine; Drug Interactions; Endorphins; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Naloxone; Protein Precursors; Rabbits; Receptors, Opioid | 1982 |
beta-Endorphin inhibits met-enkephalin breakdown by a brain aminopeptidase: structure-activity relationships.
Topics: Aminopeptidases; Animals; beta-Endorphin; Binding Sites; Brain; Endorphins; Enkephalin, Methionine; Enkephalins; Kinetics; Rats; Structure-Activity Relationship | 1982 |
The influence of selective adeno- and neurointermedio-hypophysectomy upon plasma and brain levels of beta-endorphin and their response to stress in rats.
Topics: Animals; beta-Endorphin; Brain Chemistry; Endorphins; Enkephalin, Methionine; Enkephalins; Hypophysectomy; Male; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains | 1982 |
Characterization of the dopamine stimulated adenylate cyclase in the pedal ganglia of Mytilus edulis: interactions with etorphine, beta-endorphin, DALA, and methionine enkephalin.
Topics: Adenylyl Cyclases; Animals; beta-Endorphin; Bivalvia; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Etorphine; Ganglia; Kinetics; Morphinans | 1981 |
Enzymatic cleavage prior to antibody incubation as a method for neuropeptide immunocytochemistry.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Carboxypeptidases; Endorphins; Enkephalins; Immunoenzyme Techniques; Neurosecretion; Octopodiformes; Pituitary Gland; Pituitary Gland, Posterior; Rats; Trypsin; Vasopressins | 1982 |
Nerve growth factor induces specific enkephalin binding sites in a nerve cell line.
Topics: Animals; beta-Endorphin; Cell Line; Endorphins; Enkephalin, Methionine; Enkephalins; Kinetics; Morphine; Naloxone; Nerve Growth Factors; Pheochromocytoma; Rats; Receptors, Opioid | 1982 |
Regulation of the in vitro antibody response by neuroendocrine hormones.
Topics: Adrenocorticotropic Hormone; Animals; Antibody Formation; beta-Endorphin; Cells, Cultured; Endorphins; Enkephalins; Female; Interferon Inducers; Kinetics; Lymphocytes; Mercaptoethanol; Mice; Mice, Inbred C57BL; Naloxone | 1982 |
beta-Endorphin enhances lymphocyte proliferative responses.
Topics: Analgesics; Animals; beta-Endorphin; Concanavalin A; DNA Replication; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Lymphocyte Activation; Lymphocytes; Male; Naloxone; Rats; Rats, Inbred Lew | 1982 |
Analysis of peptides in tissue and plasma. Use of silicic acid extraction and reversed-phase columns for rapid purification prior to radioimmunoassay.
Topics: Animals; beta-Endorphin; Brain Chemistry; Chromatography, High Pressure Liquid; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Peptides; Radioimmunoassay; Rats | 1982 |
Enkephalin and beta-endorphin as mediators of electro-acupuncture analgesia in rabbits: an antiserum microinjection study.
Topics: Acupuncture Therapy; Analgesia; Animals; beta-Endorphin; Endorphins; Enkephalins; Immune Sera; Injections, Spinal; Male; Microinjections; Morphine; Rabbits | 1982 |
Opiate receptor-mediated inhibition of catecholamine release in primary cultures of bovine adrenal chromaffin cells.
Topics: Acetylcholine; Adrenal Medulla; Animals; beta-Endorphin; Catecholamines; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Cyclazocine; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Phenazocine; Receptors, Opioid | 1982 |
Immunocytochemical study of Wulzen's cone of the bovine pituitary.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; beta-Lipotropin; Calcitonin; Cattle; Endorphins; Enkephalins; Fluorescent Antibody Technique; Luteinizing Hormone; Melanocyte-Stimulating Hormones; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Prolactin; Thyrotropin | 1982 |
Inhibition of tail-flick and shaking responses by intrathecal and intraventricular D-Ala2-D-Leu5-enkephalin and beta-endorphin in anesthetized rats.
Topics: Analgesics; Anesthesia; Animals; Behavior, Animal; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Injections, Spinal; Male; Pentobarbital; Rats; Rats, Inbred Strains | 1983 |
The epileptogenic spectrum of opiate agonists.
Topics: Animals; Anticonvulsants; beta-Endorphin; Cyclazocine; Electroencephalography; Endorphins; Enkephalin, Leucine; Epilepsy; Ethylketocyclazocine; Injections, Intraventricular; Male; Naloxone; Narcotics; Phenazocine; Rats; Rats, Inbred Strains | 1982 |
Effect of morphine, ACTH, epinephrine, Met-, Leu- and des-Tyr-Met-enkephalin on beta-endorphin-like immunoreactivity of rat brain.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Brain Chemistry; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Epinephrine; Female; Morphine; Rats | 1982 |
Ontogenesis of opiate binding sites and radioimmunoassayable beta-endorphin and enkephalin in regions of rat brain.
Topics: Aging; Animals; Animals, Newborn; beta-Endorphin; Brain; Endorphins; Enkephalins; Female; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Role of opioid peptides in brain mechanisms regulating blood pressure.
Topics: Animals; beta-Endorphin; Blood Pressure; Brain; Endorphins; Enkephalins; Heart Rate; Hypertension; Male; Medulla Oblongata; Naloxone; Nociceptors; Pain; Rats; Sensory Thresholds | 1983 |
[Transport of calcium to synaptosomes and subcellular membrane fractions of the brain: effects of opioid peptides].
Topics: Animals; beta-Endorphin; Biological Transport, Active; Brain; Calcium; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Intracellular Membranes; Kinetics; Male; Microsomes; Mitochondria; Rats; Synaptosomes | 1982 |
Increase in potencies of opioid peptides after peptidase inhibition.
Topics: Animals; beta-Endorphin; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Leucine; Male; Mice; Myenteric Plexus; Protease Inhibitors; Rats; Rats, Inbred Strains; Vas Deferens | 1983 |
Peptide and non-peptide opioid-induced hyperthermia in rabbits.
Topics: Animals; beta-Endorphin; Body Temperature; Cyclazocine; Endorphins; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Male; Morphine; Naloxone; Peptides; Phenazocine; Rats | 1983 |
Synthesis of porcine leumorphin and some of its biological activities.
Topics: Analgesia; Animals; beta-Endorphin; Biological Assay; Dynorphins; Electric Stimulation; Endorphins; Enkephalins; Guinea Pigs; Ileum; Indicators and Reagents; Mice; Muscle Contraction; Naloxone; Narcotics; Peptide Fragments; Protein Precursors; Swine | 1983 |
Functional opiate receptor in mouse vas deferens: evidence for a complex interaction.
Topics: Animals; Arylsulfatases; beta-Endorphin; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Mice; Mice, Inbred ICR; Morphine; Muscle Contraction; Naloxone; Receptors, Opioid; Sulfatases; Vas Deferens | 1983 |
Analysis of enkephalins, beta-endorphins and small peptides in their sequences by highly sensitive high-performance liquid chromatography with electrochemical detection: implications in opioid peptide metabolism.
Topics: Adrenal Cortex Hormones; Amino Acid Sequence; Aminopeptidases; Animals; beta-Endorphin; Brain Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Endopeptidases; Endorphins; Enkephalins; Male; Peptides; Rats; Rats, Inbred Strains | 1983 |
Multi-dimensional analyses of behavior in mice treated with morphine, endorphins and [des-tyrosine1]-gamma-endorphin.
Topics: Animals; Behavior, Animal; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Male; Mice; Morphine; Naltrexone; Peptide Fragments | 1983 |
Alcohol and central nervous system peptides.
Topics: Alcohol Drinking; Alcoholism; Animals; beta-Endorphin; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Humans; Mice; Mice, Inbred C57BL; Rats; Receptors, Opioid; Social Environment | 1983 |
Anesthesia does not increase opioid peptides in cerebrospinal fluid of humans.
Topics: Analgesia; Anesthesia, General; beta-Endorphin; Endorphins; Enkephalin, Leucine; Halothane; Humans; Nitrous Oxide; Thiopental; Time Factors | 1984 |
Biochemical and pharmacological evidence for opioid receptor multiplicity in the central nervous system.
Topics: Analgesia; Animals; beta-Endorphin; Brain; Endorphins; Enkephalins; Meptazinol; Morphine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration | 1983 |
Effect of human B-endorphin on the binding of different opiates to mouse brain membranes.
Topics: Animals; beta-Endorphin; Brain; Cell Membrane; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Humans; Kinetics; Mice; Receptors, Opioid | 1983 |
Measurement of beta-endorphin and enkephalins in biological tissues and fluids.
Topics: Animals; Antigen-Antibody Complex; beta-Endorphin; Brain Chemistry; Chromatography, High Pressure Liquid; Endorphins; Enkephalin, Methionine; Enkephalins; Humans; Immune Sera; Iodine Radioisotopes; Pituitary Gland; Radioimmunoassay; Radioisotope Dilution Technique; Tritium | 1983 |
Immunocytochemistry of endorphins and enkephalins.
Topics: Animals; beta-Endorphin; Brain; Endorphins; Enkephalins; Fluorescent Antibody Technique; Freezing; Histocytochemistry; Immunoenzyme Techniques; Indicators and Reagents; Neurons; Rats | 1983 |
Beta-endorphin-, leucine enkephalin- and methionine enkephalin-like immunoreactivity in human cerebrospinal fluid. Simultaneous determination and relation to neurological disorders.
Topics: Adolescent; Adult; Aged; beta-Endorphin; Central Nervous System Diseases; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Male; Middle Aged | 1984 |
Alterations of plasma opioid activity in human diabetics.
Topics: beta-Endorphin; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Humans; Insulin; Obesity; Radioimmunoassay; Radioligand Assay; Reference Values | 1984 |
Comparison of the effectiveness of different opioid peptides in suppressing heroin withdrawal.
Topics: Adult; Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Heroin; Humans; Male; Mice; Peptide Fragments; Protein Precursors; Substance Withdrawal Syndrome | 1984 |
A photoaffinity reagent to label the opiate receptors of guinea pig ileum and mouse vas deferens.
Topics: Affinity Labels; Animals; Azides; beta-Endorphin; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guinea Pigs; Ileum; Male; Mice; Naloxone; Photochemistry; Receptors, Opioid; Vas Deferens | 1984 |
Opioid antagonism of electroshock-induced seizures.
Topics: Animals; beta-Endorphin; Electroshock; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotics; Seizures; Time Factors | 1984 |
The ontogeny of seizures induced by leucine-enkephalin and beta-endorphin.
Topics: Aging; Animals; beta-Endorphin; Brain; Electroencephalography; Endorphins; Enkephalin, Leucine; Evoked Potentials; Male; Naloxone; Rats; Rats, Inbred Strains; Seizures | 1984 |
The effects of des-enkephalin-gamma-endorphin and des-Tyr1-a-endorphin on regional serotonin metabolism in rat brain.
Topics: Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Brain; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Hippocampus; Hypothalamus, Middle; Male; Mesencephalon; Peptide Fragments; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin | 1982 |
Brain distributions of alpha-neo-endorphin and beta-neo-endorphin: evidence for regional processing differences.
Topics: Animals; beta-Endorphin; Brain Chemistry; Cross Reactions; Endorphins; Enkephalins; Hypothalamus; Male; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1982 |
Regional distribution of beta-neo-endorphin in rat brain and pituitary.
Topics: Animals; beta-Endorphin; Brain Chemistry; Chromatography, High Pressure Liquid; Enkephalins; Male; Pituitary Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Tissue Distribution | 1982 |
Beta-neo-endorphin, a new hypothalamic "big" Leu-enkephalin of porcine origin: its purification and the complete amino acid sequence.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Biological Assay; Chromatography, High Pressure Liquid; Endorphins; Enkephalins; Guinea Pigs; Ileum; Peptides; Swine | 1981 |
In vivo injection of antibodies directed against the cloned mu opioid receptor blocked supraspinal analgesia induced by mu-agonists in mice.
Topics: Amino Acid Sequence; Analgesia; Animals; Antibodies; Benzeneacetamides; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Immunization, Passive; Male; Mice; Molecular Sequence Data; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1995 |
Preparative and analytical capillary zone electrophoresis analysis of native endorphins and enkephalins extracted from the bovine pituitary: mass spectrometric confirmation of the molecular mass of leucine enkephalin.
Topics: Animals; beta-Endorphin; Capillary Action; Cattle; Chromatography, High Pressure Liquid; Electrophoresis; Endorphins; Enkephalin, Methionine; Enkephalins; Molecular Weight; Neuropeptides; Pituitary Gland; Spectrometry, Mass, Secondary Ion | 1995 |
Liquid-phase combinatorial synthesis.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; beta-Endorphin; Databases, Factual; Enkephalin, Leucine; Enzyme-Linked Immunosorbent Assay; Epitopes; Indicators and Reagents; Molecular Sequence Data; Oligopeptides; Polyethylene Glycols; Serum Albumin, Bovine; Structure-Activity Relationship; Sulfonamides | 1995 |
Differential effects of 3-isobutyl-1-methylxanthine injected intrathecally or intracerebroventricularly on antinociception induced by opioids administered intracerebroventricularly in the mouse.
Topics: 1-Methyl-3-isobutylxanthine; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 3',5'-Cyclic-AMP Phosphodiesterases; Analgesia; Animals; beta-Endorphin; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Pyrrolidines; Spinal Cord | 1995 |
Opioid peptide inhibition of endogenous norepinephrine release from the A2 noradrenergic cell group in vitro.
Topics: alpha-MSH; Animals; beta-Endorphin; Calcium; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Medulla Oblongata; Melanocyte-Stimulating Hormones; Naloxone; Norepinephrine; Opioid Peptides; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1995 |
Mitogenic activation of human T lymphocytes induces a high affinity morphine binding site.
Topics: Analgesics; beta-Endorphin; Cells, Cultured; Culture Media; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Interleukin-2; Ligands; Lymphocyte Activation; Mitogens; Morphine; Naloxone; Phytohemagglutinins; Receptors, Opioid; T-Lymphocytes | 1995 |
Inflammation of the rat paw enhances axonal transport of opioid receptors in the sciatic nerve and increases their density in the inflamed tissue.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Axonal Transport; beta-Endorphin; Biological Transport; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Foot; Freund's Adjuvant; Inflammation; Ligation; Male; Naloxone; Nerve Tissue Proteins; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sciatic Nerve | 1993 |
Brain and plasma levels of opioid peptides are altered in rats with thioacetamide-induced fulminant hepatic failure: implications for the treatment of hepatic encephalopathy with opioid antagonists.
Topics: Animals; beta-Endorphin; Brain Chemistry; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hepatic Encephalopathy; Male; Motor Activity; Narcotic Antagonists; Opioid Peptides; Rats; Rats, Sprague-Dawley; Thioacetamide | 1995 |
Antibodies to the cloned mu-opioid receptor detect various molecular weight forms in areas of mouse brain.
Topics: Amino Acid Sequence; Animals; Antibodies; beta-Endorphin; Brain Chemistry; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Male; Mice; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Rats; Rats, Wistar; Receptors, Opioid, mu | 1995 |
Effect of isolation conditions on brain regional enkephalin and beta-endorphin levels and vocalizations in 10-day-old rat pups.
Topics: Animals; Animals, Newborn; Arousal; beta-Endorphin; Brain; Brain Mapping; Enkephalins; Female; Male; Maternal Deprivation; Mesencephalon; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Social Environment; Social Isolation; Vocalization, Animal | 1995 |
Action of opioid peptides on the rat adrenal cortex: stimulation of steroid secretion through a specific mu opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenal Cortex; Aldosterone; Analgesics; Animals; beta-Endorphin; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Male; Opioid Peptides; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1995 |
Specific N- or C-terminus modified dynorphin and beta-endorphin peptides can selectively block excitatory opioid receptor functions in sensory neurons and unmask potent inhibitory effects of opioid agonists.
Topics: Action Potentials; Animals; beta-Endorphin; Cells, Cultured; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ganglia, Spinal; Mice; Morphine; Neurons; Receptors, Opioid, delta | 1995 |
Delta-opioid peptide receptors in muscles from obese diabetic and normal mice.
Topics: Analgesics; Animals; Autoradiography; beta-Endorphin; Binding, Competitive; Cell Membrane; Diabetes Mellitus; Diabetes Mellitus, Type 2; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Iodine Radioisotopes; Mice; Mice, Obese; Muscle, Skeletal; Obesity; Oligopeptides; Receptors, Opioid, delta; Reference Values | 1995 |
Role of nitric oxide/cyclic GMP in i.c.v. administered beta-endorphin- and (+)-cis-dioxolane-induced antinociception in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; Arginine; beta-Endorphin; Cyclic GMP; Dioxolanes; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hemoglobins; Injections, Intraventricular; Male; Methylene Blue; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Nitric Oxide; Nitroarginine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism | 1994 |
Differential antagonism by MK-801 against antinociception induced by opioid receptor agonists administered supraspinally in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; beta-Endorphin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Pyrrolidines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid | 1994 |
[Clinical and experimental studies of the dynamic changes in neuropeptides after trauma].
Topics: Animals; beta-Endorphin; Enkephalin, Leucine; Fractures, Bone; Humans; Male; Multiple Trauma; Oxytocin; Rats; Rats, Sprague-Dawley; Shock, Traumatic | 1994 |
Increased beta-endorphin but not Leu-enkephalin in plasma due to preoperative stress.
Topics: Adolescent; Anxiety; beta-Endorphin; Child; Child, Preschool; Enkephalin, Leucine; Female; Humans; Infant; Male; Stress, Psychological | 1995 |
Dexamethasone-induced selective inhibition of the central mu opioid receptor: functional in vivo and in vitro evidence in rodents.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; beta-Endorphin; Dexamethasone; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hippocampus; In Vitro Techniques; Male; Mice; Morphine; Oligopeptides; Pain Measurement; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, mu | 1994 |
Augmenting effect of opioid peptides on murine macrophage activation.
Topics: Animals; beta-Endorphin; Cells, Cultured; Dynorphins; Endorphins; Enkephalins; Female; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Naloxone | 1994 |
Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue.
Topics: Analysis of Variance; Animals; Antibodies; beta-Endorphin; Corticotropin-Releasing Hormone; Cyclosporine; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Inflammation; Injections; Interleukin-1; Male; Naloxone; Pain; Rats; Rats, Wistar; Recombinant Proteins; Regression Analysis; Somatostatin | 1994 |
Endogenous opioid-like substances in perinatal asphyxia and cerebral injury due to anoxia.
Topics: Asphyxia Neonatorum; beta-Endorphin; Cerebral Hemorrhage; Dynorphins; Enkephalin, Leucine; Female; Fetal Hypoxia; Humans; Infant, Newborn; Male; Peptide Fragments; Pregnancy | 1993 |
Peripheral opioid systems in cluster headache.
Topics: beta-Endorphin; Cluster Headache; Enkephalin, Methionine; Enkephalins; Humans; Neutrophils; Protein Precursors; Receptors, Opioid; Reference Values; Sympathetic Nervous System | 1994 |
Repeated ethanol differently affects opioid peptide biosynthesis in the rat pituitary.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalins; Ethanol; In Situ Hybridization; Male; Pituitary Gland; Pituitary Gland, Anterior; Pro-Opiomelanocortin; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger | 1994 |
Difference between plasma N- and C-terminally directed beta-endorphin immunoreactivity in infantile autism.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Autistic Disorder; beta-Endorphin; Child; Child, Preschool; Dopamine; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Epinephrine; Female; Humans; Male; Norepinephrine; Opioid Peptides; Peptide Termination Factors; Pro-Opiomelanocortin; Radioimmunoassay; Rett Syndrome | 1994 |
Ultrastructural evidence for synaptic inputs of enkephalinergic nerve terminals to target neurons in the rat arcuate nucleus.
Topics: 3,3'-Diaminobenzidine; Animals; Arcuate Nucleus of Hypothalamus; Benzidines; beta-Endorphin; Chromogenic Compounds; Enkephalin, Methionine; Enkephalins; Male; Microscopy, Immunoelectron; Neurons; Neuropeptide Y; Presynaptic Terminals; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 1994 |
The effects of protection by D-Pen2-D-Pen5-enkephalin or D-Ala2-NMePhe4-Gly-ol-enkephalin against beta-chlornaltrexamine in the spinal cord on the antinociception induced by beta-endorphin administered intracerebroventricularly in the mouse.
Topics: Amino Acid Sequence; Analgesics; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Spinal Cord | 1994 |
Age-related changes in the spinal antinociceptive effects of DAGO, DPDPE and beta-endorphin in the rat.
Topics: Aging; Analgesics; Analysis of Variance; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Pain; Rats; Rats, Inbred F344; Spine | 1994 |
Opioid peptides, adrenocorticotrophic hormone, and idiopathic (orthostatic) edema.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; beta-Endorphin; Blood Urea Nitrogen; Body Weight; Dextroamphetamine; Dopamine; Edema; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Hypotension, Orthostatic; Middle Aged; Renin; Sodium; Spironolactone; Syndrome; Vasopressins | 1994 |
Implantation of AtT-20 or genetically modified AtT-20/hENK cells in mouse spinal cord induced antinociception and opioid tolerance.
Topics: Animals; beta-Endorphin; Cell Line; Cell Transplantation; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Isoproterenol; Male; Mice; Mice, Inbred ICR; Narcotics; Nociceptors; Pituitary Neoplasms; Protein Precursors; Spinal Cord; Transfection; Tumor Cells, Cultured | 1994 |
Multiple opiate receptor subtypes are involved in the stimulation of growth hormone release by beta-endorphin in female rats.
Topics: Animals; beta-Endorphin; Diestrus; Enkephalin, Leucine; Female; Growth Hormone; Kinetics; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1994 |
[Changes of endogenous opioid peptides content in RPGL during acupuncture analgesia].
Topics: Acupuncture Analgesia; Animals; beta-Endorphin; Dynorphins; Electroacupuncture; Enkephalin, Leucine; Male; Medulla Oblongata; Pain Threshold; Peptide Fragments; Rats; Reticular Formation | 1993 |
Spinal involvement of both dynorphin A and Met-enkephalin in the antinociception induced by intracerebroventricularly administered bremazocine but not morphine in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Benzomorphans; beta-Endorphin; Drug Interactions; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Nociceptors; Pain Measurement; Pyrrolidines; Spinal Cord; Time Factors | 1993 |
Dynorphin modulates prolactin secretion in the turkey.
Topics: Animals; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Electric Stimulation; Enkephalin, Methionine; Enkephalins; Female; Kinetics; Prolactin; Protein Precursors; Turkeys | 1993 |
Antibodies raised against the N-terminal sequence of delta opioid receptors blocked delta-mediated supraspinal antinociception in mice.
Topics: Amino Acid Sequence; Analysis of Variance; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; GTP-Binding Proteins; Immunoglobulin G; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Morphine; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Protein Binding; Reaction Time; Receptors, Opioid, delta | 1994 |
Partial antinociceptive cross-tolerance to intracerebroventricular beta-endorphin in mice tolerant to systemic morphine.
Topics: Analgesics; Animals; beta-Endorphin; Drug Implants; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Norepinephrine; Pain Measurement; Serotonin | 1993 |
Evidence of an intermediate-size beta-endorphin-containing precursor molecule in bovine pituitary by mass spectrometry.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; Enkephalins; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Pituitary Gland; Pro-Opiomelanocortin; Protein Precursors; Trypsin | 1993 |
[Changes in plasma neuropeptides before and after clonidine in patients with essential hypertension].
Topics: Adult; Aged; beta-Endorphin; Blood Pressure; Clonidine; Enkephalin, Leucine; Female; Humans; Hypertension; Male; Middle Aged; Neuropeptides; Renin | 1993 |
[Changes in regulatory peptides at different stages of essential hypertension and their clinical significance].
Topics: beta-Endorphin; Captopril; Enkephalin, Leucine; Humans; Hypertension; Neuropeptides; Neurotensin; Norepinephrine | 1993 |
[Protective effect of panaxatriols on function of reproductive endocrine axis in radiation-injured rats].
Topics: Animals; beta-Endorphin; Enkephalin, Leucine; Follicle Stimulating Hormone; Ginsenosides; Hypothalamus; Male; Pituitary Gland; Radiation Injuries, Experimental; Rats; Rats, Wistar; Saponins; Testosterone; Triterpenes; Whole-Body Irradiation | 1993 |
Enkephalin antinociception in mice is mediated by delta 1- and delta 2-opioid receptors in the brain and spinal cord, respectively.
Topics: Animals; Benzylidene Compounds; beta-Endorphin; Brain; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naltrexone; Pain; Receptors, Opioid, delta; Spinal Cord | 1993 |
Opioid peptide release evoked by noxious stimulation of the hind instep of rats.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; Hindlimb; Hot Temperature; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 1993 |
Ontogeny of Leu-enkephalin and beta-endorphin innervation of the preoptic area in male and female rats.
Topics: Animals; beta-Endorphin; Cell Differentiation; Cross Reactions; Enkephalin, Leucine; Female; Immunohistochemistry; Male; Pregnancy; Preoptic Area; Rats; Rats, Sprague-Dawley; Sex Characteristics | 1993 |
Effect of diabetes on the antinociceptive effect of beta-endorphin.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; beta-Endorphin; Cerebral Ventricles; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Pain; Pyrrolidines; Reference Values | 1993 |
Beta-endorphin is a potent inhibitor of thymidine incorporation into DNA via mu- and kappa-opioid receptors in fetal rat brain cell aggregates in culture.
Topics: Animals; beta-Endorphin; Brain; Cell Aggregation; Cells, Cultured; DNA; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Fetus; Kinetics; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thymidine; Tritium | 1993 |
Schistosoma mansoni: an enkephalinergic system that may participate in internal and host-parasite signaling.
Topics: Animals; beta-Endorphin; Binding, Competitive; Biomphalaria; Cell Communication; Cricetinae; Enkephalin, Methionine; Enkephalins; Host-Parasite Interactions; Naloxone; Radioimmunoassay; Receptors, Opioid; Schistosoma mansoni; Signal Transduction; Trypsin; Trypsin Inhibitors | 1993 |
Spinal delta 2 but not delta 1 opioid receptors are involved in intracerebroventricular beta-endorphin-induced antinociception in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzylidene Compounds; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Measurement; Pyrrolidines; Receptors, Opioid, delta; Spinal Cord | 1993 |
Opiate receptor subtype involvement in the stimulation of prolactin release by beta-endorphin in female rats.
Topics: Animals; beta-Endorphin; Diestrus; Dose-Response Relationship, Drug; Enkephalin, Leucine; Female; Lactation; Male; Naltrexone; Narcotic Antagonists; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1993 |
Inhibition of spinal opioid antinociception by intrathecal beta-endorphin1-27 in the rat.
Topics: Analgesics; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Injections, Spinal; Male; Morphine; Narcotic Antagonists; Narcotics; Pain Measurement; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reaction Time; Sheep; Spinal Cord | 1993 |
In vivo injection of antisense oligodeoxynucleotides to G alpha subunits and supraspinal analgesia evoked by mu and delta opioid agonists.
Topics: Analgesics, Opioid; Animals; Base Sequence; beta-Endorphin; Blotting, Western; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Injections, Intraventricular; Mice; Molecular Sequence Data; Morphine; Oligonucleotides, Antisense; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
Opioid and tachykinin neuropeptides in prolactin-secreting human pituitary adenomas.
Topics: Adenoma; Adult; Aged; Amino Acid Sequence; beta-Endorphin; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Enkephalins; Female; Humans; Immunohistochemistry; In Vitro Techniques; Male; Mass Spectrometry; Middle Aged; Molecular Sequence Data; Opioid Peptides; Pituitary Gland; Pituitary Neoplasms; Pro-Opiomelanocortin; Prolactin; Protein Precursors; Substance P; Tachykinins | 1995 |
Involvement of different subtypes of cholecystokinin receptors in opioid antinociception in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; beta-Endorphin; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Injections, Intraventricular; Male; Meglumine; Mice; Mice, Inbred ICR; Morphine; Narcotics; Pain Measurement; Proglumide; Pyrrolidines; Receptors, Cholecystokinin; Sincalide | 1995 |
Plasma levels of beta-endorphin, leucine enkephalin and arginine vasopressin in patients with essential hypertension and the effects of clonidine.
Topics: Angiotensin II; Antihypertensive Agents; Arginine Vasopressin; beta-Endorphin; Blood Pressure; Clonidine; Enkephalin, Leucine; Female; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Naloxone; Narcotic Antagonists; Neurotensin; Renin; Time Factors | 1995 |
Tolerance of hypothalamic beta-endorphin neurons to mu-opioid receptor activation after chronic morphine.
Topics: Analgesics, Opioid; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Guinea Pigs; Hypothalamus; Morphine; Receptors, Opioid, mu | 1996 |
Neuropeptides accentuate interleukin-4 induced human immunoglobuline E synthesis in vitro.
Topics: Adrenocorticotropic Hormone; alpha-Endorphin; alpha-MSH; Animals; Antibody Formation; B-Lymphocytes; beta-Endorphin; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Leucine; gamma-Endorphin; Humans; Immunoglobulin E; Interleukin-4; Mice; Neuropeptides; Substance P | 1996 |
Endogenous opioid peptides in parasympathetic, sympathetic and sensory nerves in the guinea-pig heart.
Topics: Adrenergic Fibers; Animals; Antibody Specificity; Axons; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Ganglia, Autonomic; Guinea Pigs; Heart; Immunohistochemistry; Male; Neurons, Afferent; Opioid Peptides; Parasympathetic Fibers, Postganglionic; Protein Precursors | 1996 |
State-dependent changes of brain endogenous opioids in mammalian hibernation.
Topics: Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Hibernation; Male; Opioid Peptides; Radioimmunoassay; Sciuridae | 1996 |
Combinatorial chemistry: a liquid-phase approach.
Topics: Amino Acid Sequence; Antibodies; beta-Endorphin; Drug Evaluation, Preclinical; Enkephalin, Leucine; Enzyme-Linked Immunosorbent Assay; Ligands; Molecular Sequence Data; Oligopeptides; Polyethylene Glycols; Protein Binding; Solubility; Sulfonamides | 1996 |
Chronic intracerebroventricular administration of beta-endorphin augments natural killer cell cytotoxicity in rats.
Topics: Administration, Cutaneous; Animals; beta-Endorphin; Cytotoxicity, Immunologic; Dynorphins; Enkephalins; Injections, Intraventricular; Killer Cells, Natural; Lymphocyte Activation; Lymphoma; Male; Rats; Rats, Inbred SHR; Tumor Cells, Cultured | 1996 |
Autoradiographic evidence of mu-opioid receptors down-regulation after prenatal stress in offspring rat brain.
Topics: Analgesics; Animals; Autoradiography; beta-Endorphin; Brain Chemistry; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stress, Physiological; Tritium | 1996 |
Influence of opioid peptides on the priming action of estrogen on lordosis in ovariectomized rats.
Topics: Animals; beta-Endorphin; Enkephalin, Leucine; Enkephalin, Methionine; Estrogens; Female; Injections, Intraventricular; Male; Opioid Peptides; Ovariectomy; Posture; Rats; Rats, Sprague-Dawley; Sexual Behavior, Animal | 1996 |
Involvement of beta-endorphin in the modulation of paw inflammatory edema in the rat.
Topics: Animals; Antibodies; Benzomorphans; beta-Endorphin; Edema; Enkephalin, Leucine; Foot; Inflammation; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Yeasts | 1996 |
Portacaval anastomosis induces region-selective alterations of the endogenous opioid system in the rat brain.
Topics: Alcohol Drinking; Analysis of Variance; Animals; beta-Endorphin; Brain; Brain Chemistry; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Naloxone; Narcotic Antagonists; Pituitary Gland; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 1996 |
Pretreatment with pertussis toxin differentially modulates morphine- and beta-endorphin-induced antinociception in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics, Opioid; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Pertussis Toxin; Pyrrolidines; Receptors, Serotonin; Virulence Factors, Bordetella | 1996 |
Intrathecally injected nicotine enhances the antinociception induced by morphine but not beta-endorphin, D-Pen2,5-enkephalin and U50,488H administered intrathecally in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Opioid; Analysis of Variance; Animals; beta-Endorphin; Drug Synergism; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Nicotine; Pyrrolidines; Receptors, Opioid, delta; Spinal Cord | 1996 |
Nicotine enhances morphine- and beta-endorphin-induced antinociception at the supraspinal level in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; beta-Endorphin; Drug Synergism; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Nicotine; Nociceptors; Pain; Pain Measurement; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1996 |
Activation of mu-opioid receptors are required for the conditioned enhancement of NK cell activity.
Topics: Animals; beta-Endorphin; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Spinal; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Morphinans; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu | 1996 |
Pretreatment with protein kinase C activator phorbol 12,13-dibutyrate attenuates the antinociception induced by mu- but not epsilon-opioid receptor agonist in the mouse.
Topics: Analgesics; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naphthalenes; Nociceptors; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Opioid; Receptors, Opioid, mu; Time Factors | 1997 |
Opioid receptor-coupled G-proteins in rat locus coeruleus membranes: decrease in activity after chronic morphine treatment.
Topics: Analgesics; Analgesics, Opioid; Animals; beta-Endorphin; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Locus Coeruleus; Male; Membrane Proteins; Morphine; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sulfur Radioisotopes | 1997 |
Differential modulation by muscimol and baclofen on antinociception induced by morphine, beta-endorphin, D-Pen2,5-enkephalin and U50,488H administered intracerebroventricularly in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Analysis of Variance; Animals; Baclofen; beta-Endorphin; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Mice; Morphine; Muscimol; Pyrrolidines; Receptors, GABA; Receptors, Opioid, kappa | 1995 |
Neuronal regulation of interleukin 6 secretion in murine spleen: adrenergic and opioidergic control.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analgesics; Animals; beta-Endorphin; Clonidine; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Interleukin-6; Isoproterenol; Mice; Mice, Inbred Strains; Morphinans; Naloxone; Narcotic Antagonists; Neurons; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Opioid; Spleen | 1997 |
Actions of beta-endorphin peptides on the contractions of mouse diaphragm muscle.
Topics: Animals; Benzylidene Compounds; beta-Endorphin; Diaphragm; Dipeptides; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Mice; Mice, Inbred C57BL; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neostigmine; Oligopeptides; Peptide Fragments | 1997 |
[Met5]enkephalin and delta2-opioid receptors in the spinal cord are involved in the cold water swimming-induced antinociception in the mouse.
Topics: Animals; beta-Endorphin; Cold Temperature; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Pain; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1997 |
Differential effects of omega-conotoxin GVIA, nimodipine, calmidazolium and KN-62 injected intrathecally on the antinociception induced by beta-endorphin, morphine and [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin administered intracerebroventricularly in the mous
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; beta-Endorphin; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Imidazoles; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Nimodipine; omega-Conotoxin GVIA; Peptides; Spinal Cord | 1997 |
Differential effects of beta-endorphin and Met- and Leu-enkephalin on steroid hormone-induced lordosis in ovariectomized female rats.
Topics: Animals; beta-Endorphin; Enkephalin, Leucine; Enkephalin, Methionine; Female; Injections, Intraventricular; Male; Naloxone; Narcotic Antagonists; Ovariectomy; Posture; Rats; Rats, Sprague-Dawley; Sexual Behavior, Animal; Steroids | 1997 |
Enkephalins modulate differentiation of normal human keratinocytes in vitro.
Topics: beta-Endorphin; Cell Differentiation; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Humans; Keratinocytes; Keratins; Melphalan; Naltrexone; Narcotic Antagonists; Skin; Transglutaminases | 1997 |
Fine-tuning control of testicular functions.
Topics: Animals; beta-Endorphin; Corticotropin-Releasing Hormone; Enkephalins; Immune Sera; Injections; Male; Naloxone; Narcotic Antagonists; Oxidopamine; Oxytocin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Somatostatin; Sympathectomy; Testis; Vasectomy | 1997 |
The peptide orphanin FQ inhibits beta-endorphin neurons and neurosecretory cells in the hypothalamic arcuate nucleus by activating an inwardly-rectifying K+ conductance.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Barium Compounds; beta-Endorphin; Chlorides; Electric Conductivity; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Guinea Pigs; Neurons; Neurosecretory Systems; Nociceptin; Opioid Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Receptors, Opioid; Receptors, Opioid, mu | 1998 |
Myocardial turnover of endogenous opioids and calcitonin-gene-related peptide in the human heart and the effects of spinal cord stimulation on pacing-induced angina pectoris.
Topics: Aged; Angina Pectoris; beta-Endorphin; Calcitonin Gene-Related Peptide; Cardiac Catheterization; Cardiac Pacing, Artificial; Electric Stimulation Therapy; Electrodes, Implanted; Enkephalin, Leucine; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Myocardium; Radioimmunoassay; Spinal Cord | 1998 |
The C-terminal tetrapeptide of beta-endorphin (MPF) enhances lymphocyte proliferative responses.
Topics: Animals; beta-Endorphin; Cell Division; Concanavalin A; Dipeptides; Dose-Response Relationship, Immunologic; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Glutamic Acid; Glycine; Humans; Lymphocyte Activation; Mitogens; Oligopeptides; Peptide Fragments; Rats; Species Specificity; T-Lymphocytes | 1998 |
Stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding by endogenous opioids acting at a cloned mu receptor.
Topics: Animals; beta-Endorphin; Cells, Cultured; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Opioid Peptides; Rats; Receptors, Opioid, mu; Recombinant Proteins; Tumor Cells, Cultured | 1998 |
Involvement of mu-receptor in endogenous opioid peptide-mediated inhibition of acetylcholine release from the rat stomach.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; beta-Endorphin; Electric Stimulation; Enkephalins; Gastric Mucosa; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Rats; Receptors, Opioid, mu; Stomach; Vagus Nerve | 1998 |
Brain opioid receptor adaptation and expression after prenatal exposure to buprenorphine.
Topics: Adaptation, Physiological; Animals; Animals, Newborn; beta-Endorphin; Brain; Buprenorphine; Cross-Linking Reagents; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Narcotic Antagonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, Opioid; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction | 1998 |
Immunolocalization of regulatory peptides and 5-HT in bovine male urogenital apparatus.
Topics: Animals; beta-Endorphin; Bombesin; Calcitonin Gene-Related Peptide; Cattle; Enkephalins; Gastrin-Releasing Peptide; Genitalia, Male; Humans; Male; Neuropeptide Y; Neuropeptides; Serotonin; Somatostatin; Substance P; Urinary Tract; Vasoactive Intestinal Peptide | 1998 |
Opioid receptor ligands in human hepatic encephalopathy.
Topics: beta-Endorphin; Enkephalin, Leucine; Enkephalin, Methionine; Hepatic Encephalopathy; Humans; Ligands; Radioimmunoassay; Receptors, Opioid | 1998 |
[Effects of long-term and high intensity exercise on plasma beta-endorphin, dynorphin A1-13, leucine-enkephalin and lactate in rats].
Topics: Analgesics, Opioid; Animals; beta-Endorphin; Dynorphins; Enkephalin, Leucine; Lactic Acid; Male; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley | 1997 |
Nota bene: biomedicine. Pain-killer genes.
Topics: Animals; beta-Endorphin; Chronic Disease; Enkephalin, Methionine; Enkephalins; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Mice; Pain Management; Protein Precursors; Simplexvirus; Spinal Cord | 1999 |
The proenkephalin A-processing product peptide E, which encompasses two enkephalin sequences, has a much lower opioid activity than beta-endorphin.
Topics: Amino Acid Sequence; Animals; Behavior, Animal; beta-Endorphin; Cattle; Enkephalins; Male; Mice; Molecular Sequence Data; Pain Measurement; Protein Conformation; Protein Precursors; Rana ridibunda; Recombinant Fusion Proteins; Species Specificity | 1999 |
Met5-enkephalin protects isolated adult rabbit cardiomyocytes via delta-opioid receptors.
Topics: Animals; beta-Endorphin; Cell Hypoxia; Cells, Cultured; Enkephalin, Leucine; Enkephalin, Methionine; Heart; Ischemic Preconditioning; Male; Models, Cardiovascular; Morphine; Myocardial Ischemia; Myocardium; Naloxone; Rabbits; Rats; Receptors, Opioid, delta | 1999 |
ARC POMC mRNA and PVN alpha-MSH are lower in obese relative to lean zucker rats.
Topics: alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Blood Glucose; Dynorphins; Energy Metabolism; Enkephalins; Feeding Behavior; Gene Expression; Insulin; Leptin; Male; Melanocytes; Neuropeptide Y; Obesity; Paraventricular Hypothalamic Nucleus; Pro-Opiomelanocortin; Protein Precursors; Rats; Rats, Zucker; RNA, Messenger | 2000 |
Antisense inhibition of pro-opiomelanocortin and proenkephalin A messenger RNA translation alters rat immune cell function in vitro.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Cells, Cultured; Enkephalins; Immune System; Male; Oligonucleotides, Antisense; Pro-Opiomelanocortin; Protein Biosynthesis; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Spleen | 2000 |
Interleukin-2: structural and biological relatedness to opioid peptides.
Topics: Analgesics; Animals; Antibodies; Antibodies, Monoclonal; beta-Endorphin; Brain Chemistry; Cross Reactions; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-2; Male; Mutagenesis, Site-Directed; Neuroimmunomodulation; Nociceptors; Opioid Peptides; Pain Threshold; Peptide Fragments; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Structure-Activity Relationship | 2000 |
Involvement of dynorphin in immobilization stress-induced antinociception in the mouse.
Topics: Animals; beta-Endorphin; Cerebral Ventricles; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Reaction Time; Restraint, Physical; Stress, Psychological | 2000 |
Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat.
Topics: Animals; beta-Endorphin; Brain; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Hydrochloric Acid; Male; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stomach Ulcer; Vagotomy | 2001 |
Antisera against endogenous opioids increase the nocifensive response to formalin: demonstration of inhibitory beta-endorphinergic control.
Topics: Animals; beta-Endorphin; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Formaldehyde; Immune Sera; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Nociceptors; Opioid Peptides; Pain | 2001 |
Endorphin and enkephalin ameliorate excessive synovial cell functions in patients with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; beta-Endorphin; Cell Division; Cell Nucleus; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Enkephalin, Leucine; Enkephalin, Methionine; Female; Gene Expression; Humans; Interleukin-1; Male; Matrix Metalloproteinase 9; Middle Aged; Neuroimmunomodulation; Opioid Peptides; Receptors, Opioid; Synovial Membrane; Synovitis; Tumor Necrosis Factor-alpha | 2001 |
[Distinct structural bases of the immunoregulatory and central analgesic effects of IFNalpha].
Topics: Adjuvants, Immunologic; Analgesics, Opioid; Animals; beta-Endorphin; Cross Reactions; Enkephalin, Leucine; Epitopes; Interferon-alpha; Male; Mutagenesis, Site-Directed; Rats; Rats, Sprague-Dawley | 2000 |
[Melatonin influences the release of endogenous opioid peptides in rat periaqueductal gray].
Topics: Analgesics, Opioid; Animals; beta-Endorphin; Enkephalin, Leucine; Male; Melatonin; Pain Threshold; Periaqueductal Gray; Random Allocation; Rats | 2000 |
Selective reward deficit in mice lacking beta-endorphin and enkephalin.
Topics: Animals; Behavior, Animal; beta-Endorphin; Choice Behavior; Conditioning, Operant; Eating; Enkephalins; Extinction, Psychological; Feeding Behavior; Food Deprivation; Genotype; Male; Mice; Mice, Knockout; Motivation; Phenotype; Reward | 2002 |
[Respiratory and hemodynamic responses to microinjections of opioids into the solitary tract nucleus].
Topics: Animals; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Leucine; Female; Hemodynamics; Male; Microinjections; Morphine; Narcotic Antagonists; Narcotics; Rats; Respiration; Solitary Nucleus | 1997 |
[The postburn change in hypothalamic paraventricular beta-endorphin and the roles of delta-receptor in scalded rats].
Topics: Analgesics, Opioid; Animals; beta-Endorphin; Blood Pressure; Burns; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Heart Rate; Male; Narcotic Antagonists; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Survival Analysis | 2002 |
[Study on the relationship between endogenous opioid peptides and fetal distress].
Topics: Adult; beta-Endorphin; Dynorphins; Enkephalin, Leucine; Female; Fetal Blood; Fetal Distress; Humans; Opioid Peptides; Pregnancy | 2002 |
The regulation of steroidogenesis by opioid peptides in porcine theca cells.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; beta-Endorphin; Cells, Cultured; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Estradiol; Female; Opioid Peptides; Progesterone; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Steroids; Swine; Testosterone; Theca Cells | 2003 |
State-dependent modulation of feeding behavior by proopiomelanocortin-derived beta-endorphin.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Body Weight; Brain; Conditioning, Operant; Dynorphins; Eating; Energy Metabolism; Enkephalins; Feeding Behavior; Female; Homeostasis; Male; Mice; Mice, Knockout; Pro-Opiomelanocortin | 2003 |
Changes of central norepinephrine, beta-endorphin, LEU-enkephalin, peripheral arginine-vasopressin, and angiotensin II levels in acute and chronic phases of sino-aortic denervation in rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Baroreflex; beta-Endorphin; Blood Pressure; Brain; Chronic Disease; Denervation; Enkephalin, Leucine; Heart Rate; Hypertension; Male; Norepinephrine; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sinoatrial Node | 2004 |
Occurrence of ACTH- and enkephalin-like peptides in the developing gut of Dicentrarchus labrax L.
Topics: Adrenocorticotropic Hormone; Aging; alpha-MSH; Animals; Bass; beta-Endorphin; Digestive System; Enkephalins; Immunohistochemistry; Larva; Pro-Opiomelanocortin | 2004 |
Nonopioidergic mechanism mediating morphine-induced antianalgesia in the mouse spinal cord.
Topics: Analgesia; Animals; beta-Endorphin; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Dynorphins; Enkephalins; Male; Mice; Morphine; Naloxone; Naltrexone; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substance P | 2004 |
The influence of opioid peptides on steroidogenesis in porcine granulosa cells.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Granulosa Cells; Luteinizing Hormone; Opioid Peptides; Ovarian Follicle; Swine | 2004 |
Operant self-administration of ethanol in C57BL/6 mice lacking beta-endorphin and enkephalin.
Topics: Alcohol Drinking; Animals; beta-Endorphin; Conditioning, Operant; Dose-Response Relationship, Drug; Enkephalins; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Reinforcement, Psychology | 2004 |
Differential mechanisms of antianalgesia induced by endomorphin-1 and endomorphin-2 in the ventral periaqueductal gray of the rat.
Topics: Analgesia; Animals; beta-Endorphin; Cholecystokinin; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Receptors, Opioid, mu; Substance P | 2005 |
Electroacupuncture induces c-Fos expression in the rostral ventrolateral medulla and periaqueductal gray in cats: relation to opioid containing neurons.
Topics: Animals; Axons; beta-Endorphin; Blood Pressure; Cats; Dendrites; Electroacupuncture; Enkephalins; Heart Rate; Immunohistochemistry; Medulla Oblongata; Neurons; Periaqueductal Gray; Proto-Oncogene Proteins c-fos | 2004 |
Anti-inflammatory and opioid-mediated effects of melatonin on experimental peritonitis in chickens.
Topics: Adjuvants, Immunologic; Animals; beta-Endorphin; Cell Proliferation; Chickens; Disease Models, Animal; Enkephalins; Gene Expression; Macrophages, Peritoneal; Male; Melatonin; Naltrexone; Narcotic Antagonists; Opioid Peptides; Peritonitis; Pro-Opiomelanocortin; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spleen; Thioglycolates | 2005 |
Endogenous enkephalins, not endorphins, modulate basal hedonic state in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; beta-Endorphin; Conditioning, Operant; Dose-Response Relationship, Drug; Enkephalins; Lithium Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Protein Precursors; Reaction Time | 2005 |
Delta and mu opioid receptors from the brain of a urodele amphibian, the rough-skinned newt Taricha granulosa: cloning, heterologous expression, and pharmacological characterization.
Topics: Amino Acid Sequence; Animals; Base Sequence; beta-Endorphin; Brain Chemistry; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Molecular Sequence Data; Naloxone; Phylogeny; Receptors, Opioid, delta; Receptors, Opioid, mu; Salamandridae; Sequence Alignment | 2006 |
Only arginine vasopressin, not oxytocin and endogenous opiate peptides, in hypothalamic paraventricular nucleus play a role in acupuncture analgesia in the rat.
Topics: Acupuncture Analgesia; Afferent Pathways; Animals; Arginine Vasopressin; beta-Endorphin; Dynorphins; Electric Stimulation; Enkephalin, Leucine; Extracellular Fluid; Hypothalamo-Hypophyseal System; Immunohistochemistry; Male; Neurons; Opioid Peptides; Oxytocin; Pain; Paraventricular Hypothalamic Nucleus; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Up-Regulation | 2006 |
The contribution of endogenous opioids to food reward is dependent on sex and background strain.
Topics: Animals; beta-Endorphin; Conditioning, Operant; Enkephalins; Female; Food; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Reinforcement Schedule; Reward; Sex Characteristics; Species Specificity | 2007 |
Arginine vasopressin induces periaqueductal gray release of enkephalin and endorphin relating to pain modulation in the rat.
Topics: Acetylcholine; Animals; Arginine Vasopressin; beta-Endorphin; Choline; Dopamine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Epinephrine; gamma-Aminobutyric Acid; Glutamic Acid; Male; Norepinephrine; Opioid Peptides; Oxytocin; Pain; Pain Threshold; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Serotonin | 2007 |
Essential role of mu opioid receptor in the regulation of delta opioid receptor-mediated antihyperalgesia.
Topics: Animals; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Protein Precursors; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin | 2007 |
Control of hormonal stress reactivity by the endogenous opioid system.
Topics: Adrenocorticotropic Hormone; Amygdala; Analysis of Variance; Animals; Anxiety; beta-Endorphin; Corticosterone; Dynorphins; Enkephalins; Exploratory Behavior; Hypothermia; Limbic System; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Opioid Peptides; Paraventricular Hypothalamic Nucleus; Protein Precursors; Proto-Oncogene Proteins c-fos; Reflex, Startle; Stress, Psychological; Time Factors | 2008 |
Detection of a novel immunoreactive endomorphin 2-like peptide in rat brain extracts.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Enkephalins; Immune Sera; Male; Mice; Narcotic Antagonists; Oligopeptides; Peptides; Rabbits; Radioimmunoassay; Rats; Rats, Wistar | 2008 |
The opioid peptides enkephalin and beta-endorphin in alcohol dependence.
Topics: Adult; Alcohol Drinking; Alcoholism; Animals; beta-Endorphin; Body Weight; Choice Behavior; Disease Models, Animal; Enkephalins; Female; Food Preferences; Gene Frequency; Genotype; Humans; Linkage Disequilibrium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Polymorphism, Single Nucleotide; Pro-Opiomelanocortin; Sex Characteristics; Stress, Psychological | 2008 |
Does the endogenous opiate system play a role in the Restless Legs Syndrome? A pilot post-mortem study.
Topics: Aged; Aged, 80 and over; beta-Endorphin; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Immunohistochemistry; Male; Pilot Projects; Restless Legs Syndrome; Substantia Nigra; Thalamus; Tyrosine 3-Monooxygenase | 2009 |
Hypertensive state, independent of hypertrophy, exhibits an attenuated decrease in systolic function on cardiac kappa-opioid receptor stimulation.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antihypertensive Agents; Benzamides; beta-Endorphin; Blood Pressure; Cricetinae; Cyclic AMP; Disease Models, Animal; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypertension; Hypertrophy, Left Ventricular; Myocardial Contraction; Myocardium; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Systole; Ventricular Remodeling | 2009 |
Practical aspects of in vivo detection of neuropeptides by microdialysis coupled off-line to capillary LC with multistage MS.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Corpus Striatum; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Limit of Detection; Male; Microdialysis; Neuropeptides; Oligopeptides; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization | 2009 |
Enkephalins, dynorphins, and beta-endorphin in the rat dorsal horn: an immunofluorescence colocalization study.
Topics: Animals; beta-Endorphin; Dynorphins; Enkephalins; Fluorescent Antibody Technique; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Fibers, Unmyelinated; Neural Pathways; Neurons; Neurons, Afferent; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord | 2009 |
Structural and pharmacological characteristics of chimeric peptides derived from peptide E and beta-endorphin reveal the crucial role of the C-terminal YGGFL and YKKGE motifs in their analgesic properties.
Topics: Amino Acid Motifs; Amino Acid Sequence; Analgesics; Animals; beta-Endorphin; Circular Dichroism; Enkephalins; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Sequence Data; Pain; Peptides; Structure-Activity Relationship | 2010 |
Stress-induced analgesia and endogenous opioid peptides: the importance of stress duration.
Topics: Analgesia; Analgesics, Opioid; Animals; beta-Endorphin; Dynorphins; Enkephalins; Female; Hot Temperature; Mice; Mice, Inbred C57BL; Mice, Knockout; Naloxone; Nociceptors; Opioid Peptides; Pain Measurement; Stress, Psychological; Swimming; Time Factors | 2011 |
Oxytocin in the periaqueductal gray participates in pain modulation in the rat by influencing endogenous opiate peptides.
Topics: Animals; beta-Endorphin; Catheterization; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Microinjections; Naloxone; Narcotic Antagonists; Oxytocin; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Periaqueductal Gray; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 2011 |
The novel role of cathepsin L for neuropeptide production illustrated by research strategies in chemical biology with protease gene knockout and expression.
Topics: alpha-MSH; Amino Acid Sequence; Animals; beta-Endorphin; Cathepsin L; Dynorphins; Endopeptidases; Enkephalins; Gene Knockout Techniques; Humans; Lysosomes; Mice; Mice, Knockout; Neuropeptides; Peptide Hormones; Proprotein Convertases; Protein Precursors; Protein Processing, Post-Translational; Secretory Vesicles | 2011 |
[Effects of electroacupuncture on pain reactions, expression of spinal kappa-opioid receptor and contents of enkephalin and beta-endorphin in periaqueductal gray of midbrain in dysmenorrhea model rats].
Topics: Acupuncture Points; Animals; beta-Endorphin; Disease Models, Animal; Dysmenorrhea; Electroacupuncture; Enkephalins; Female; Humans; Mesencephalon; Pain Management; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Spine | 2012 |
The role of endogenous beta-endorphin and enkephalins in ethanol reward.
Topics: Animals; beta-Endorphin; Choice Behavior; Conditioning, Psychological; Dose-Response Relationship, Drug; Enkephalins; Ethanol; Female; Mice; Mice, Knockout; Naloxone; Narcotic Antagonists; Protein Precursors; Reward | 2013 |
Intimate associations between the endogenous opiate systems and the growth hormone-releasing hormone system in the human hypothalamus.
Topics: Aged; Aged, 80 and over; Axons; beta-Endorphin; Dynorphins; Enkephalin, Leucine; Female; Growth Hormone-Releasing Hormone; Humans; Hypothalamus; Immunohistochemistry; Male; Median Eminence; Neurons; Opioid Peptides; Pituitary Gland, Posterior | 2014 |
Lack of interleukin-17 leads to a modulated micro-environment and amelioration of mechanical hypersensitivity after peripheral nerve injury in mice.
Topics: Animals; Behavior, Animal; beta-Endorphin; Central Nervous System Sensitization; Cytokines; Disease Models, Animal; Dynorphins; Enkephalins; Hyperalgesia; Inflammation; Interleukin-10; Interleukin-13; Interleukin-17; Interleukin-1beta; Interleukin-2; Interleukin-6; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuralgia; Neutrophils; Nociception; Peripheral Nerve Injuries; Peroxidase; Sciatic Nerve; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2014 |
Effect of intravenous general anaesthesia with epidural block on the expression of pre-endogenous opioid peptide genes.
Topics: Abdomen; Adult; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; beta-Endorphin; Bupivacaine; Dynorphins; Enkephalin, Leucine; Enkephalins; Female; Fentanyl; Gene Expression; Humans; Male; Midazolam; Middle Aged; Pain; Prospective Studies; Protein Precursors; Radioimmunoassay; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vecuronium Bromide | 2014 |
Analgesic effect of different moxibustion durations in rheumatoid arthritis rats.
Topics: Acupuncture Points; Analgesia; Animals; Arthralgia; Arthritis, Rheumatoid; beta-Endorphin; Disease Models, Animal; Enkephalins; Humans; Hypothalamus; Male; Moxibustion; Pain Threshold; Pro-Opiomelanocortin; Protein Precursors; Rats; Rats, Wistar | 2014 |
Involvement of Endogenous Enkephalins and β-Endorphin in Feeding and Diet-Induced Obesity.
Topics: Animals; Appetite; beta-Endorphin; Body Weight; Case-Control Studies; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Enkephalins; Feeding Behavior; Female; Food Deprivation; Male; Mice; Mice, Knockout; Obesity; Protein Precursors; Sucrose | 2015 |
Sensory Neuropeptides and Endogenous Opioids Expression in Human Dental Pulp with Asymptomatic Inflammation: In Vivo Study.
Topics: Adolescent; Analgesics, Opioid; beta-Endorphin; Calcitonin Gene-Related Peptide; Child; Dental Pulp; Enkephalins; Female; Humans; Inflammation; Male; Methionine; Molar; Neuropeptides; Orthodontics; Pain; Pilot Projects; Radioimmunoassay; Substance P | 2015 |
Endometriosis Is Associated With a Shift in MU Opioid and NMDA Receptor Expression in the Brain Periaqueductal Gray.
Topics: Animals; beta-Endorphin; Endometriosis; Enkephalin, Leucine; Enkephalin, Methionine; Female; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu | 2016 |
Acupuncture at distant myofascial trigger spots enhances endogenous opioids in rabbits: a possible mechanism for managing myofascial pain.
Topics: Acupuncture Points; Acupuncture Therapy; Animals; beta-Endorphin; Enkephalins; Facial Pain; Ganglia, Spinal; Male; Muscle, Skeletal; Pain Management; Rabbits; Trigger Points | 2016 |
[Effect of Small Knife Needle on β-enorpin and Enkehalin Contents of Tansverse Process Syndrome of the Third Vertebra].
Topics: Acupuncture Points; Animals; beta-Endorphin; Electroacupuncture; Enkephalins; Hypothalamus; Lumbar Vertebrae; Muscle, Skeletal; Needles; Rabbits; Random Allocation; Spinal Cord; Spinal Diseases | 2016 |
Effects of aqueous extracts from Panax ginseng and Hippophae rhamnoides on acute alcohol intoxication: An experimental study using mouse model.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholic Intoxication; Aldehyde Dehydrogenase; Animals; beta-Endorphin; Blood Alcohol Content; Brain; Cytochrome P-450 Enzyme System; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Leucine; Ethanol; Gas Chromatography-Mass Spectrometry; Hippophae; Liver; Male; Mice; Panax; Phytotherapy; Plant Extracts; Plants, Medicinal; Solvents; Time Factors; Water | 2016 |
Opioid receptor and β-arrestin2 densities and distribution change after sexual experience in the ventral tegmental area of male rats.
Topics: Animals; beta-Arrestin 2; beta-Endorphin; Ejaculation; Enkephalins; Male; Opioid Peptides; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Sexual Behavior, Animal; Ventral Tegmental Area | 2018 |
nNOS immunoreactivity co-localizes with GABAergic and cholinergic neurons, and associates with β-endorphinergic and met-enkephalinergic opioidergic fibers in rostral ventromedial medulla and A5 of the mouse.
Topics: Animals; beta-Endorphin; Brain Stem; Cholinergic Neurons; Enkephalins; GABAergic Neurons; Male; Medulla Oblongata; Mice; Midbrain Raphe Nuclei; Nitric Oxide Synthase Type I; Pain; Prefrontal Cortex; Receptors, Opioid; Serotonergic Neurons; Serotonin | 2018 |
Endogenous Opioid Signaling in the Mouse Retina Modulates Pupillary Light Reflex.
Topics: Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Light; Mice; Opioid Peptides; Peptides; Receptors, Opioid; Receptors, Opioid, mu; Reflex; Retina; Retinal Ganglion Cells; Signal Transduction; Visual Perception | 2021 |
Beta-endorphin inhibits the inflammatory response of bovine endometrial cells through δ opioid receptor in vitro.
Topics: Animal Husbandry; Animals; beta-Endorphin; Cattle; Cells, Cultured; Endometritis; Endometrium; Enkephalin, Leucine; Epithelial Cells; Escherichia coli; Female; Inflammation; Lipopolysaccharides; Naloxone; Narcotic Antagonists; NF-kappa B; Primary Cell Culture; Puerperal Infection; Receptors, Opioid, delta; Signal Transduction | 2021 |
Green Light Antinociceptive and Reversal of Thermal and Mechanical Hypersensitivity Effects Rely on Endogenous Opioid System Stimulation.
Topics: Animals; beta-Endorphin; Disease Models, Animal; Enkephalins; Male; Neuralgia; Phototherapy; Protein Precursors; Rats; Spinal Cord | 2021 |
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software | 1994 |
Cloning and pharmacological characterization of a rat kappa opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Cell Line; Cell Membrane; Cloning, Molecular; Corpus Striatum; Cyclic AMP; DNA Primers; DNA, Complementary; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Library; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Molecular Sequence Data; Pyrrolidines; Rats; Receptors, Opioid, kappa; Restriction Mapping; RNA, Messenger; Transfection | 1993 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |