enkephalin, leucine has been researched along with baclofen in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (15.15) | 18.7374 |
| 1990's | 27 (81.82) | 18.2507 |
| 2000's | 1 (3.03) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burgis, V; Edwards, JD; Frederickson, RC; Harrell, CE | 1 |
| Aghajanian, GK; Guyenet, PG | 1 |
| Kelly, MJ; Loose, MD; Ronnekleiv, OK | 2 |
| Dunwiddie, TV; Lupica, CR; Proctor, WR | 1 |
| Boelen, MK; Chubb, IW; Dowton, M; Morgan, IG; Wellard, J | 1 |
| Alberch, J; Arenas, E; Marsal, J | 1 |
| Kehl, SJ; McLennan, H | 1 |
| Murakoshi, T; Otsuka, M; Tamai, S; Yanagisawa, M | 1 |
| Labella, FS; Sawynok, J | 1 |
| Jenner, P; Jolkkonen, J; Marsden, CD | 1 |
| Childers, SR; Selley, DE; Sim, LJ | 1 |
| Kelly, MJ; Lagrange, AH; Rønnekleiv, OK | 1 |
| Narahashi, T; Nomura, K; Reuveny, E | 1 |
| Kalivas, PW; Klitenick, MA | 1 |
| Lambert, NA; Wilson, WA | 1 |
| Churchill, L; Hooks, MS; Johnson, K; Kalivas, PW; Klitenick, MA | 1 |
| Feldman, JL; Johnson, SM; Smith, JC | 1 |
| Christie, MJ; Osborne, PB; Vaughan, CW; Wilson, HI | 1 |
| Kelly, MJ; Lagrange, AH; Rønnekleiv, OK; Wagner, EJ | 1 |
| Feuerstein, TJ; Gleichauf, O; Jackisch, R; Landwehrmeyer, GB; Peckys, D; Scheremet, R | 1 |
| Avoli, M; Barbarosie, M; Köhling, R | 1 |
| Kelly, MJ; Lagrange, AH; Rønnekleiv, OK; Wagner, EJ; Zhang, G | 1 |
| Choi, YS; Kim, YH; Song, DK; Suh, HW; Tseng, LF; Yoo, JS | 1 |
| Jan, LY; Lüscher, C; Malenka, RC; Nicoll, RA; Stoffel, M | 1 |
| Grudt, TJ; Henderson, G | 1 |
| Moises, HC; Rusin, KI | 1 |
| Lupica, CR; Svoboda, KR | 1 |
| Churchill, L; Kalivas, PW; Klitenick, MA | 1 |
| Chavkin, C; Jin, W | 1 |
| Christie, MJ; Connor, M; Pintar, JE; Schuller, A | 1 |
| Bekkers, JM; Chieng, B | 1 |
| Chiu, K; Evans, CJ; Kieffer, BL; Maidment, NT; Walwyn, WM; Wei, W; Xie, CW | 1 |
33 other study(ies) available for enkephalin, leucine and baclofen
| Article | Year |
|---|---|
Dual actions of substance P on nociception: possible role of endogenous opioids.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Mice; Naloxone; Nociceptors; Receptors, Opioid; Structure-Activity Relationship; Substance P | 1978 |
ACh, substance P and met-enkephalin in the locus coeruleus: pharmacological evidence for independent sites of action.
Topics: Acetylcholine; Animals; Baclofen; Endorphins; Enkephalins; Locus Coeruleus; Male; Naloxone; Parasympatholytics; Parasympathomimetics; Rats; Receptors, Cholinergic; Substance P; Synaptic Transmission | 1979 |
Estrogen suppresses mu-opioid- and GABAB-mediated hyperpolarization of hypothalamic arcuate neurons.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Estradiol; Evoked Potentials; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; In Vitro Techniques; Membrane Potentials; Neurons; Ovariectomy; Receptors, Opioid; Receptors, Opioid, mu; Tetrodotoxin | 1992 |
Dissociation of mu and delta opioid receptor-mediated reductions in evoked and spontaneous synaptic inhibition in the rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Axons; Baclofen; Bicuculline; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Synapses | 1992 |
Neurons in the rat arcuate nucleus are hyperpolarized by GABAB and mu-opioid receptor agonists: evidence for convergence at a ligand-gated potassium conductance.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; beta-Endorphin; Cell Polarity; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Glycinergic control of [Leu5]enkephalin levels in chicken retina.
Topics: Animals; Baclofen; Chickens; Enkephalin, Leucine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Muscimol; Neurotransmitter Agents; Picrotoxin; Radioimmunoassay; Retina; Strychnine | 1991 |
GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
A pharmacological characterization of chloride- and potassium-dependent inhibitions in the CA3 region of the rat hippocampus in vitro.
Topics: Animals; Baclofen; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hippocampus; In Vitro Techniques; Kainic Acid; Neural Inhibition; Neural Pathways; Norepinephrine; Potassium; Rats; Synapses | 1985 |
Tail-pinch method in vitro and the effects of some antinociceptive compounds.
Topics: Analgesics; Animals; Animals, Newborn; Baclofen; Drug Evaluation, Preclinical; Enkephalin, Leucine; Enkephalin, Methionine; Humans; In Vitro Techniques; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Stereotyped Behavior; Tail | 1984 |
GABA and baclofen potentiate the K+-evoked release of methionine-enkephalin from rat striatal slices.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Corpus Striatum; Drug Synergism; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Picrotoxin; Potassium; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
GABAergic modulation of striatal peptide expression in rats and the alterations induced by dopamine antagonist treatment.
Topics: Animals; Baclofen; Benzazepines; Corpus Striatum; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enkephalins; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Haloperidol; In Situ Hybridization; Male; Muscimol; Protein Precursors; Rats; Rats, Wistar; Receptors, GABA; RNA, Messenger; Salicylamides; Substance P; Tachykinins; Vigabatrin | 1994 |
In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding.
Topics: Animals; Autoradiography; Baclofen; Benzoxazines; Brain; Cannabinoids; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA-B Receptor Agonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Morpholines; Naloxone; Naphthalenes; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid, mu | 1995 |
Estradiol-17 beta and mu-opioid peptides rapidly hyperpolarize GnRH neurons: a cellular mechanism of negative feedback?
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Estradiol; Feedback; Female; Gonadotropin-Releasing Hormone; Guinea Pigs; Membrane Potentials; Naloxone; Neurons; Ovariectomy; Potassium Channels; Receptors, Opioid, mu; Tetrodotoxin | 1995 |
Opioid inhibition and desensitization of calcium channel currents in rat dorsal root ganglion neurons.
Topics: Analgesics; Animals; Baclofen; Calcium Channel Blockers; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ganglia, Spinal; Guanosine 5'-O-(3-Thiotriphosphate); Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1994 |
Behavioral and neurochemical studies of opioid effects in the pedunculopontine nucleus and mediodorsal thalamus.
Topics: Amino Acid Sequence; Animals; Baclofen; Behavior, Animal; Dopamine; Dorsomedial Hypothalamic Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Extracellular Space; Haloperidol; Male; Microinjections; Molecular Sequence Data; Motor Activity; Nucleus Accumbens; Pons; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Synaptic Transmission; Ventral Tegmental Area | 1994 |
Heterogeneity in presynaptic regulation of GABA release from hippocampal inhibitory neurons.
Topics: Analgesics; Animals; Baclofen; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Homeostasis; In Vitro Techniques; Male; Naloxone; Nerve Fibers; Neurons; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Synapses | 1993 |
Involvement of the ventral tegmental area in locomotion elicited from the nucleus accumbens or ventral pallidum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Globus Pallidus; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 1996 |
Modulation of respiratory rhythm in vitro: role of Gi/o protein-mediated mechanisms.
Topics: Analgesics; Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; GTP-Binding Proteins; In Vitro Techniques; Rats; Respiration; Serotonin | 1996 |
Opioid inhibition of rat periaqueductal grey neurones with identified projections to rostral ventromedial medulla in vitro.
Topics: Analgesics; Animals; Baclofen; Brain; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Fluorescent Dyes; GABA Agonists; In Vitro Techniques; Microspheres; Narcotics; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Rhodamines | 1996 |
Estrogen rapidly attenuates a GABAB response in hypothalamic neurons.
Topics: Animals; Baclofen; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Estradiol; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; Neurons; Potassium Channels; Receptors, GABA; Receptors, Opioid, mu | 1996 |
Opioid receptor-mediated control of acetylcholine release in human neocortex tissue.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Adolescent; Adult; Aged; Analgesics; Analysis of Variance; Baclofen; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; GABA Agonists; Humans; Male; Middle Aged; Muscimol; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, delta; Tetrodotoxin | 1996 |
Anoxia blocks the presynaptic control of GABA release at inhibitory terminals in the rat hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Baclofen; Cell Hypoxia; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Neurons; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1996 |
Tolerance to mu-opioid receptor agonists but not cross-tolerance to gamma-aminobutyric acid(B) receptor agonists in arcuate A12 dopamine neurons with chronic morphine treatment.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Drug Tolerance; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; GABA-B Receptor Agonists; Guinea Pigs; Hypothalamus; In Vitro Techniques; Membrane Potentials; Morphine; Morphine Dependence; Neurons; Receptors, Opioid, mu; Tetrodotoxin; Tyrosine 3-Monooxygenase | 1997 |
Differential modulation by muscimol and baclofen on antinociception induced by morphine, beta-endorphin, D-Pen2,5-enkephalin and U50,488H administered intracerebroventricularly in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Analysis of Variance; Animals; Baclofen; beta-Endorphin; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Mice; Morphine; Muscimol; Pyrrolidines; Receptors, GABA; Receptors, Opioid, kappa | 1995 |
G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Baclofen; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; GTP-Binding Proteins; Hippocampus; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Potassium Channels; Potassium Channels, Inwardly Rectifying; Presynaptic Terminals; Pyramidal Cells; Receptors, Adrenergic, alpha-1; Receptors, GABA-B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Synaptic Membranes; Transcription, Genetic | 1997 |
Glycine and GABAA receptor-mediated synaptic transmission in rat substantia gelatinosa: inhibition by mu-opioid and GABAB agonists.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Postsynaptic Potentials; Female; GABA Agents; GABA Antagonists; GABA-B Receptor Agonists; Glycine Agents; In Vitro Techniques; Male; Membrane Potentials; Narcotic Antagonists; Patch-Clamp Techniques; Peptide Fragments; Peptides; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glycine; Receptors, Opioid, mu; Somatostatin; Strychnine; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 1998 |
Mu-opioid and GABA(B) receptors modulate different types of Ca2+ currents in rat nodose ganglion neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics, Opioid; Animals; Baclofen; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Agonists; GABA Antagonists; Naloxone; Narcotic Antagonists; Nerve Tissue Proteins; Neurons; Nifedipine; Nodose Ganglion; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Spider Venoms | 1998 |
Opioid inhibition of hippocampal interneurons via modulation of potassium and hyperpolarization-activated cation (Ih) currents.
Topics: Analgesics; Analgesics, Opioid; Animals; Baclofen; Barium; Cardiovascular Agents; Cations; Cell Size; Cells, Cultured; Cesium; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Interneurons; Male; Membrane Potentials; Potassium; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 1998 |
Dopamine depletion reorganizes projections from the nucleus accumbens and ventral pallidum that mediate opioid-induced motor activity.
Topics: Analgesics, Opioid; Animals; Baclofen; Dopamine; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fluphenazine; GABA Agonists; Globus Pallidus; Locomotion; Male; Microinjections; Motor Activity; Motor Neurons; Muscimol; Neural Pathways; Nucleus Accumbens; Oxidopamine; Rats; Rats, Sprague-Dawley; Sympatholytics | 1998 |
Mu opioids enhance mossy fiber synaptic transmission indirectly by reducing GABAB receptor activation.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Antagonists; Long-Term Potentiation; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission | 1999 |
Mu-opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1.
Topics: Animals; Baclofen; Calcium Channels; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Periaqueductal Gray; Receptors, Opioid, mu | 1999 |
GABA(B), opioid and alpha2 receptor inhibition of calcium channels in acutely-dissociated locus coeruleus neurones.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Baclofen; Barium; Brimonidine Tartrate; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Electrophysiology; Enkephalins; GABA Agonists; GABA-B Receptor Agonists; In Vitro Techniques; Locus Coeruleus; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, Opioid | 1999 |
Mu opioid receptor-effector coupling and trafficking in dorsal root ganglia neurons.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Flow Cytometry; GABA Agonists; Ganglia, Spinal; Membrane Potentials; Mice; Mice, Knockout; Morphine; Neurons; Patch-Clamp Techniques; Protein Transport; Receptors, Opioid, mu; Time Factors; Transfection | 2006 |