enkephalin, leucine has been researched along with alpha-neoendorphin in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (67.86) | 18.7374 |
| 1990's | 15 (26.79) | 18.2507 |
| 2000's | 2 (3.57) | 29.6817 |
| 2010's | 1 (1.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pittman, QJ; Thornhill, JA | 1 |
| Baldwin, BA; de la Riva, C; Ebenezer, IS | 1 |
| Apte, RN; Durum, SK; Oppenheim, JJ | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R | 2 |
| Macdonald, RL; Werz, MA | 1 |
| Ens, W; Mayer, F; Standing, KG; Tang, X; Westmore, JB | 1 |
| Dores, RM; Richard, R; Sei, CA | 1 |
| Murphy, R; Steele, PA; Turner, CA | 1 |
| Brownstein, MJ; Eiden, LE; Eskay, RL; Faden, AI; Feuerstein, G; Palkovits, M; Weber, E; Zamir, D; Zamir, N | 1 |
| Imura, H; Inoue, T; Kabayama, Y; Kato, Y; Matsushita, N; Ohta, H; Shimatsu, A; Tojo, K; Yanaihara, N | 1 |
| Herz, A; Schiller, PW; Schulz, R; Shearman, GT | 1 |
| Zamir, N | 1 |
| Barchas, JD; Evans, CJ; Lorenz, RG | 1 |
| Hartschuh, W; Weber, E; Weihe, E | 1 |
| Nordström, K; Nyberg, F; Terenius, L | 1 |
| Akil, H; Dores, RM | 1 |
| Brownstein, MJ; Dawbarn, D; Emson, PC; Hunt, SP; Waters, CM; Zamir, N | 1 |
| Colpaert, FC; Członkowski, A; Herz, A; Höllt, V; Millan, MH; Millan, MJ; Pilcher, CW | 1 |
| Colombo, M; Heym, C; Kummer, W; Lang, R | 1 |
| Cox, BM; Hassen, AH; Molineaux, CJ; Rosenberger, JG | 1 |
| Castanas, E; Cazalis, M; Dayanithi, G; Giraud, P; Legros, JJ; Louis, F; Nordmann, JJ | 1 |
| Acker, GR; Molineaux, C; Orlowski, M | 1 |
| Ibayashi, H; Kato, K; Nawata, H; Yanase, T | 1 |
| Herz, A; Leibold, A; Millan, MJ; Nohr, D; Weihe, E | 1 |
| Cetin, Y | 1 |
| Dandekar, T; Gramsch, C; Metzner, K; Schulz, R | 1 |
| Rubini, P; Schulz, R; Wüster, M | 1 |
| Fujino, M; Imura, H; Katakami, H; Kato, Y; Matsuo, H; Matsushita, N; Shimatsu, A | 1 |
| Barchas, JD; Geis, R; Voigt, KH; Weber, E | 1 |
| Hayashi, K; Ikeda, Y; Imura, H; Nakao, K; Sakamoto, M; Suda, M; Yoshimasa, T | 1 |
| Ikeda, Y; Imura, H; Jingami, H; Nakai, Y; Nakao, K; Oki, S; Sakamoto, M; Suda, M; Tanaka, I; Tsukada, T; Yoshimasa, T | 1 |
| Barchas, JD; Cone, RI; Goldstein, A; Weber, E | 1 |
| Grimm, C; Herz, A; Höllt, V; Seizinger, BR | 1 |
| Fischli, W; Goldstein, A; James, IF | 1 |
| Herz, A; Höllt, V; Seizinger, BR | 1 |
| Cox, BM; Molineaux, CJ; Rosenberger, JG | 1 |
| Bannon, MJ; Helke, CJ; Jacobowitz, DM; Kopin, IJ; Skofitsch, G; Zamir, N | 1 |
| Grimm, C; Herz, A; Liebisch, DC; Seizinger, BR | 1 |
| Ishizuka, Y; Kajiwara, M; Matsumiya, T; Negishi, K; Oka, T; Watanabe, Y | 1 |
| Ho, WK; Wen, HL; Wen, PY | 1 |
| Archelos, J; Lang, RE; Xiang, JZ | 1 |
| Barchas, JD; Chang, JK; Evans, CJ; Weber, E | 1 |
| Nylander, I; Silberring, J; Tan-No, K; Winter, A | 1 |
| Healy, DJ; Meador-Woodruff, JH | 1 |
| Meador-Woodruff, JH; Ramsdell, CD | 1 |
| de Costa, BR; Kayakiri, H; Ni, Q; Partilla, JS; Rice, KC; Rothman, RB; Xu, H | 1 |
| Beauvillain, JC; Bulet, P; Malecha, J; Salzet, M; Verger-Bocquet, M | 1 |
| Chrousos, GP; Gravanis, A; Karl, M; Margioris, AN; Saviolakis, GA | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R; Turchan, J | 3 |
| Alrubaian, J; Danielson, P; Dores, RM; Walker, D | 1 |
| Chen, C; Chen, Y; Liu-Chen, LY | 1 |
| Bakalkin, G; Dooley, C; Marrink, SJ; McLaughlin, J; Melo, MN; Reits, E; Sinke, RJ; Smeets, CJ; Stargardt, A; Verbeek, DS; Zmorzyńska, J | 1 |
| Akil, H; Goldstein, A; Mansour, A; Meng, F; Thompson, RC; Watson, SJ; Xie, GX | 1 |
2 review(s) available for enkephalin, leucine and alpha-neoendorphin
| Article | Year |
|---|---|
Functional response of multiple opioid systems to chronic arthritic pain in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Arthritis; Arthritis, Experimental; Benzomorphans; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Morphine; Naloxone; Nociceptors; Pain; Pituitary Gland, Anterior; Protein Precursors; Pyrrolidines; Rats; Receptors, Opioid; Sensory Thresholds; Spinal Cord; Thalamus | 1986 |
Biosynthesis and distribution of opioid peptides.
Topics: Adrenal Medulla; Adrenocorticotropic Hormone; Animals; beta-Endorphin; beta-Lipotropin; Brain; Dynorphins; Endorphins; Enkephalins; Gastric Mucosa; Humans; Ileum; Melanocyte-Stimulating Hormones; Pituitary Gland; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors | 1983 |
54 other study(ies) available for enkephalin, leucine and alpha-neoendorphin
| Article | Year |
|---|---|
Hemodynamic responses of conscious rats following intrathecal injections of prodynorphin-derived opioids: independence of action of intrathecal arginine vasopressin.
Topics: Animals; Arginine Vasopressin; beta-Endorphin; Blood Pressure; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Heart Rate; Hemodynamics; Injections, Spinal; Male; Narcotics; Norepinephrine; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred Strains | 1990 |
Effects of intracerebroventricular injection of dynorphin, leumorphin and alpha neo-endorphin on operant feeding in pigs.
Topics: Animals; Appetitive Behavior; Brain; Conditioning, Operant; Dynorphins; Endorphins; Enkephalins; Feeding Behavior; Female; Injections, Intraventricular; Male; Motivation; Naloxone; Peptide Fragments; Protein Precursors; Receptors, Opioid; Swine | 1990 |
Opioids modulate interleukin-1 production and secretion by bone-marrow macrophages.
Topics: Animals; beta-Endorphin; Bone Marrow Cells; Drug Synergism; Endorphins; Enkephalins; Interleukin-1; Lipopolysaccharides; Macrophages; Mice; Naloxone; Protein Precursors; Silicon Dioxide | 1990 |
The release of alpha-neoendorphin from rat hippocampus following kainic acid-induced seizures.
Topics: Animals; Endorphins; Enkephalins; Hippocampus; Kainic Acid; Male; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Seizures | 1990 |
Dynorphin and neoendorphin peptides decrease dorsal root ganglion neuron calcium-dependent action potential duration.
Topics: Action Potentials; Animals; beta-Endorphin; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Ganglia, Spinal; Ion Channels; Mice; Naloxone; Protein Precursors; Receptors, Opioid; Sodium; Time Factors | 1985 |
Measurement of unimolecular decay in peptides of masses greater than 1200 units by a reflecting time-of-flight mass spectrometer.
Topics: Endorphins; Enkephalin, Leucine; Mass Spectrometry; Protein Precursors; Substance P | 1989 |
Steady-state levels of pro-dynorphin-related end-products from the brain of the amphibian, Xenopus laevis.
Topics: Animals; Brain; Dynorphins; Endorphins; Enkephalins; Protein Precursors; Xenopus laevis | 1989 |
Measurement and chromatographic characterization of prodynorphin-derived peptides in the guinea-pig ileum.
Topics: Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalins; Guinea Pigs; Ileum; Peptide Fragments; Protein Precursors; Radioimmunoassay | 1989 |
Methionine and leucine enkephalin in rat neurohypophysis: different responses to osmotic stimuli and T2 toxin.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Osmosis; Oxytocin; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic; Sesquiterpenes; T-2 Toxin; Vasopressins; Water Deprivation | 1985 |
Stimulation by leumorphin of prolactin secretion from the pituitary in rats.
Topics: Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalins; Injections, Intraventricular; Male; Naloxone; Pituitary Gland, Anterior; Prolactin; Protein Precursors; Rats; Swine; Thyrotropin-Releasing Hormone | 1985 |
Generalization tests with intraventricularly applied pro-enkephalin B-derived peptides in rats trained to discriminate the opioid kappa receptor agonist ethylketocyclazocine.
Topics: Animals; beta-Endorphin; Cyclazocine; Discrimination Learning; Dynorphins; Endorphins; Enkephalins; Ethylketocyclazocine; Generalization, Stimulus; Injections, Intraventricular; Male; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
On the origin of Leu-enkephalin and Met-enkephalin in the rat neurohypophysis.
Topics: Animals; Arginine Vasopressin; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus, Middle; Male; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Sodium Glutamate | 1985 |
Effects of dehydration on pro-dynorphin derived peptides in the neuro-intermediate lobe of the rat pituitary.
Topics: Animals; beta-Endorphin; Dehydration; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Food Deprivation; Hypothalamus; Male; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains | 1985 |
Prodynorphin opioid peptides in small somatosensory primary afferents of guinea pig.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Ganglia, Spinal; Guinea Pigs; Male; Neurons, Afferent; Neurotransmitter Agents; Peripheral Nerves; Protein Precursors; Somatosensory Cortex; Trigeminal Ganglion | 1985 |
Endopeptidase in human cerebrospinal fluid which cleaves proenkephalin B opioid peptides at consecutive basic amino acids.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Humans; Hydrolysis; Protein Precursors; Radioimmunoassay; Serine Endopeptidases; Serine Proteinase Inhibitors | 1985 |
Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey.
Topics: Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Corpus Striatum; Dynorphins; Endorphins; Enkephalins; Female; Macaca mulatta; Peptide Fragments; Protein Precursors; Radioimmunoassay; Substantia Nigra | 1985 |
Peptides derived from prodynorphin are decreased in basal ganglia of Huntington's disease brains.
Topics: Basal Ganglia; Caudate Nucleus; Dynorphins; Endorphins; Enkephalins; Globus Pallidus; Humans; Huntington Disease; Protein Precursors; Putamen; Substantia Nigra | 1986 |
Immunohistochemical evidence for extrinsic and intrinsic opioid systems in the guinea pig superior cervical ganglion.
Topics: Animals; Cross Reactions; Dynorphins; Endorphins; Enkephalin, Leucine; Female; Ganglia, Sympathetic; Guinea Pigs; Immune Sera; Immunoenzyme Techniques; Protein Precursors | 1986 |
Response of rat pituitary anterior lobe prodynorphin products to changes in gonadal steroid environment.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Female; Gonadal Steroid Hormones; Male; Orchiectomy; Ovariectomy; Pituitary Gland, Anterior; Protein Precursors; Rats; Testosterone | 1986 |
Are opioid peptides co-localized with vasopressin or oxytocin in the neural lobe of the rat?
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Histological Techniques; Neurophysins; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Vasopressins | 1986 |
Synaptosomal membrane-bound form of endopeptidase-24.15 generates Leu-enkephalin from dynorphin1-8, alpha- and beta-neoendorphin, and Met-enkephalin from Met-enkephalin-Arg6-Gly7-Leu8.
Topics: Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Endopeptidases; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Metalloendopeptidases; Peptide Fragments; Protease Inhibitors; Protein Precursors; Rats; Rats, Inbred Strains; Synaptic Membranes; Synaptosomes; Trypsin | 1987 |
Preproenkephalin B-derived opioid peptides in human phaeochromocytomas.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Cells, Cultured; Dynorphins; Endorphins; Enkephalins; Epinephrine; Female; Glucagon; Humans; Male; Middle Aged; Nicotine; Norepinephrine; Pheochromocytoma; Protein Precursors; Radioimmunoassay | 1987 |
Co-localization of proenkephalin- and prodynorphin-derived opioid peptides in laminae IV/V spinal neurons revealed in arthritic rats.
Topics: Animals; Arthritis, Rheumatoid; Dynorphins; Endorphins; Enkephalins; Male; Oligopeptides; Protein Precursors; Rats; Rats, Inbred Strains; Spinal Cord | 1988 |
Enterochromaffin (EC-) cells of the mammalian gastro-entero-pancreatic (GEP) endocrine system: cellular source of pro-dynorphin-derived peptides.
Topics: Adrenal Medulla; Animals; Cattle; Chromaffin System; Digestive System; Dogs; Dynorphins; Endorphins; Enkephalins; Enterochromaffin Cells; Guinea Pigs; Humans; Immunohistochemistry; Pancreas; Pituitary Gland; Pro-Opiomelanocortin; Protein Precursors | 1988 |
Opiates induce long-term increases in prodynorphin-derived peptide levels in the guinea-pig myenteric plexus.
Topics: Animals; Clonidine; Dextrorphan; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Ileum; Levorphanol; Male; Mice; Myenteric Plexus; Narcotic Antagonists; Narcotics; Peptides; Protein Precursors | 1986 |
The preference of putative pro-enkephalins for different types of opiate receptors.
Topics: Animals; Benzomorphans; Brain; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Ileum; Male; Mice; Morphine; Protein Precursors; Rats; Receptors, Opioid; Vas Deferens | 1981 |
Stimulation of prolactin secretion in the rat by alpha-neo-endorphin, beta-neo-endorphin and dynorphin.
Topics: Animals; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalins; Gonadotropin-Releasing Hormone; Injections, Intraventricular; Male; Naloxone; Pituitary Gland; Prolactin; Protein Precursors; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1982 |
Levels of pro-neo-endorphin/dynorphin-derived peptides in the hypothalamo-posterior pituitary system of male and female Brattleboro rats.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Female; Hypothalamus; Male; Peptides; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Brattleboro | 1983 |
Rimorphin (dynorphin B) exists together with alpha-neo-endorphin and dynorphin (dynorphin A) in human hypothalamus.
Topics: Adult; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Female; Humans; Hypothalamus; Protein Precursors | 1983 |
Regional distribution of dynorphin and neo-endorphin peptides in rat brain, spinal cord, and pituitary.
Topics: Animals; beta-Endorphin; Brain Chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Immune Sera; Male; Peptide Fragments; Peptides; Pituitary Gland; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Distribution | 1983 |
Evidence for a selective processing of proenkephalin B into different opioid peptide forms in particular regions of rat brain and pituitary.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Molecular Weight; Organ Specificity; Peptide Fragments; Pituitary Gland; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
Opioid receptor selectivity of dynorphin gene products.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Naltrexone; Peptide Fragments; Protein Precursors; Receptors, Opioid | 1984 |
Proenkephalin B (prodynorphin)-derived opioid peptides: evidence for a differential processing in lobes of the pituitary.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Molecular Weight; Peptide Fragments; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Subcellular distribution of opioid peptides in rat hypothalamus and pituitary.
Topics: Animals; Arginine Vasopressin; Centrifugation, Density Gradient; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus; Male; Peptide Fragments; Pituitary Gland; Protein Precursors; Rats; Rats, Inbred Strains; Subcellular Fractions; Synaptic Vesicles; Synaptosomes | 1984 |
Primate model of Parkinson's disease: alterations in multiple opioid systems in the basal ganglia.
Topics: Animals; Basal Ganglia; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Macaca mulatta; Male; Nucleus Accumbens; Parkinson Disease; Protein Precursors; Substantia Nigra | 1984 |
Ontogenetic development of the pro-enkephalin B (= pro-dynorphin) opioid peptide system in the rat pituitary.
Topics: Animals; Animals, Newborn; Cell Differentiation; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Female; Male; Molecular Weight; Oxytocin; Peptide Fragments; Peptides; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Pregnancy; Protein Precursors; Rats; Rats, Inbred Strains; Vasopressins | 1984 |
The choice of opiate receptor subtype by neo-endorphins.
Topics: Animals; Benzomorphans; beta-Endorphin; Cyclazocine; Drug Interactions; Endorphins; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Naloxone; Protein Precursors; Rabbits; Receptors, Opioid | 1982 |
Comparison of the effectiveness of different opioid peptides in suppressing heroin withdrawal.
Topics: Adult; Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Heroin; Humans; Male; Mice; Peptide Fragments; Protein Precursors; Substance Withdrawal Syndrome | 1984 |
Enkephalins in the heart.
Topics: Animals; Electric Stimulation; Endorphins; Enkephalins; Guinea Pigs; Heart; Hydroxydopamines; Myocardial Contraction; Myocardium; Oxidopamine; Protein Precursors; Radioimmunoassay; Sympathetic Nervous System | 1984 |
Brain distributions of alpha-neo-endorphin and beta-neo-endorphin: evidence for regional processing differences.
Topics: Animals; beta-Endorphin; Brain Chemistry; Cross Reactions; Endorphins; Enkephalins; Hypothalamus; Male; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1982 |
Processing of prodynorphin-derived peptides in striatal extracts. Identification by electrospray ionization mass spectrometry linked to size-exclusion chromatography.
Topics: Animals; Anti-Bacterial Agents; Chromatography, Gel; Corpus Striatum; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Mass Spectrometry; Peptide Hydrolases; Peptides; Protein Precursors; Rats; Sensitivity and Specificity; Tissue Extracts | 1995 |
Prodynorphin-derived peptide expression in primate cortex and striatum.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Dynorphins; Endorphins; Enkephalins; Macaca nemestrina; Peptide Fragments; Protein Precursors; Tissue Distribution | 1994 |
Repeated ethanol differently affects opioid peptide biosynthesis in the rat pituitary.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalins; Ethanol; In Situ Hybridization; Male; Pituitary Gland; Pituitary Gland, Anterior; Pro-Opiomelanocortin; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger | 1994 |
Expression of prodynorphin-derived peptides and mRNA in guinea-pig cortex.
Topics: Animals; Blotting, Northern; Cerebral Cortex; Corpus Striatum; Dynorphins; Endorphins; Enkephalins; Guinea Pigs; Male; Organ Specificity; Peptide Fragments; Protein Precursors; Radioimmunoassay; RNA, Messenger | 1993 |
Opioid peptide receptor studies. 3. Interaction of opioid peptides and other drugs with four subtypes of the kappa 2 receptor in guinea pig brain.
Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Morphinans; Opioid Peptides; Protein Precursors; Rats; Receptors, Opioid, kappa; Swine | 1995 |
Purification, sequence analysis, and cellular localization of a prodynorphin-derived peptide related to the alpha-neo-endorphin in the rhynchobdellid leech Theromyzon tessulatum.
Topics: Amino Acid Sequence; Animals; Central Nervous System; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Endorphins; Enkephalins; Immunohistochemistry; Leeches; Mass Spectrometry; Molecular Sequence Data; Protein Precursors | 1996 |
The PC12 rat pheochromocytoma cell line expresses the prodynorphin gene and secretes the 8 kDa dynorphin product.
Topics: Adrenal Medulla; Animals; Chromatography, Affinity; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalins; Gene Expression; PC12 Cells; Pheochromocytoma; Pituitary Gland; Polymerase Chain Reaction; Protein Precursors; Rats; Sequence Analysis | 1996 |
The effect of single and repeated morphine administration on the prodynorphin system activity in the nucleus accumbens and striatum of the rat.
Topics: Animals; Corpus Striatum; Endorphins; Enkephalins; Male; Morphine; Nucleus Accumbens; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger | 1996 |
Ethanol withdrawal enhances the prodynorphin system activity in the rat nucleus accumbens.
Topics: Alcohol Drinking; Animals; Endorphins; Enkephalins; In Situ Hybridization; In Vitro Techniques; Male; Nucleus Accumbens; Potassium; Protein Precursors; Rats; Rats, Wistar; Receptors, Opioid, kappa; RNA, Messenger; Substance Withdrawal Syndrome; Time Factors | 1997 |
Effects of repeated psychostimulant administration on the prodynorphin system activity and kappa opioid receptor density in the rat brain.
Topics: Amphetamine; Animals; Autoradiography; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; Endorphins; Enkephalins; In Situ Hybridization; Male; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Opioid, kappa; RNA, Messenger | 1998 |
Identification of a fourth opioid core sequence in a prodynorphin cDNA cloned from the brain of the amphibian, Bufo marinus: deciphering the evolution of prodynorphin and proenkephalin.
Topics: Acetylation; Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Bufo marinus; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA, Complementary; Endorphins; Enkephalins; Evolution, Molecular; Humans; Molecular Sequence Data; Nucleic Acid Amplification Techniques; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology | 2002 |
Dynorphin peptides differentially regulate the human kappa opioid receptor.
Topics: Animals; Binding, Competitive; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Down-Regulation; Dynorphins; Electrophoresis, Polyacrylamide Gel; Endorphins; Enkephalins; Flow Cytometry; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Peptides; Protease Inhibitors; Protein Precursors; Receptors, Opioid, kappa | 2007 |
Altered secondary structure of Dynorphin A associates with loss of opioid signalling and NMDA-mediated excitotoxicity in SCA23.
Topics: Amino Acid Sequence; Animals; Cell Culture Techniques; Computer Simulation; Dynorphins; Endorphins; Enkephalins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Neurotoxins; Protein Precursors; Protein Structure, Secondary; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord; Spinocerebellar Degenerations | 2016 |
Cloning and pharmacological characterization of a rat kappa opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Cell Line; Cell Membrane; Cloning, Molecular; Corpus Striatum; Cyclic AMP; DNA Primers; DNA, Complementary; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Library; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Molecular Sequence Data; Pyrrolidines; Rats; Receptors, Opioid, kappa; Restriction Mapping; RNA, Messenger; Transfection | 1993 |