enkephalin, leucine has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.90) | 18.7374 |
| 1990's | 12 (38.71) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chong, PN; de Ceballos, ML; Jenner, P; Marsden, CD; Rose, S; Taylor, MD | 1 |
| Duchemin, AM; Gudehithlu, KP; Hadjiconstantinou, M; Neff, NH; Tejwani, GA | 1 |
| Sheng, J | 1 |
| Chen, S | 1 |
| Agid, Y; Benoliel, JT; Cesselin, F; Javoy-Agid, F; Jenner, P; Marsden, CD; Mauborgne, A; Rose, S; Taquet, H | 1 |
| Agid, Y; Benoliel, JJ; Javoy-Agid, F; Jenner, P; Legrand, JC; Marsden, CD; Mauborgne, A; Nomoto, M; Rose, S; Taquet, H | 1 |
| Augood, SJ; Boyce, S; Clarke, CE; Crossman, AR; Emson, PC; Mitchell, IJ | 1 |
| Sheng, JG; Xu, DL; Yu, HZ | 1 |
| Jenner, P; Jolkkonen, J; Marsden, CD | 1 |
| Nishiyama, N; Schwartz, JP | 1 |
| Asselin, MC; Côté, PY; Parent, A; Soghomonian, JJ | 1 |
| Cosi, C; Harvey-White, JD; Mitsuo, K; Schwartz, JP | 1 |
| Höllt, V; Horn, G; Kupsch, A; Ziolkowska, B | 1 |
| Asselin, MC; Côté, PY; Parent, A | 1 |
| Bédard, PJ; Blanchet, PJ; Calon, F; Di Paolo, T; Goulet, M; Morissette, M; Soghomonian, JJ | 1 |
| Bédard, PJ; Di Paolo, T; Goulet, M; Grondin, R; Morissette, M | 1 |
| Haber, SN; Song, DD | 1 |
| Schneider, JS; Schroeder, JA | 1 |
| Di Monte, DA; Langston, JW; Police, S; Quik, M | 1 |
| Andrén, PE; Gunne, L; Klintenberg, R; Svenningsson, P | 1 |
| Bezard, E; Bioulac, B; Dovero, S; Gross, CE; Jaber, M; Ravenscroft, P | 1 |
| Bezard, E; Bioulac, B; Dovero, S; Gross, CE; Meissner, W | 1 |
| Brotchie, JM; Crossman, AR; Duty, S; Fox, SH; Henry, B | 1 |
| Betarbet, R; Greenamyre, JT | 1 |
| Aubert, I; Bezard, E; Bioulac, BH; Bloch, B; Crossman, AR; Dovero, S; Gross, CE; Guigoni, C; Li, Q | 1 |
| Di Paolo, T; Morissette, M | 1 |
| Brotchie, JM; Fox, SH; Johnston, T; Millan, MJ; Reyes, G; Visanji, NP | 1 |
| Aosaki, T; Imanishi, M; Inoue, R; Kobayashi, K; Masuda, M; Miura, M; Saino-Saito, S; Takada, M | 1 |
| Di Paolo, T; Grégoire, L; Jourdain, VA; Morin, N; Morissette, M | 1 |
| Battaglia, G; Bruno, V; Bucci, D; Cannella, M; Gradini, R; Molinaro, G; Motolese, M; Nicoletti, F | 1 |
| Ahn, S; Hong, S; Jang, J; Jeon, S; Jung, YR; Kim, J; Oh, JY; Park, HJ; Park, SU; Shin, HS; Song, MA; Song, TJ | 1 |
31 other study(ies) available for enkephalin, leucine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
| Article | Year |
|---|---|
Neuropeptide levels in the basal ganglia of aged common marmosets following prolonged treatment with MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Basal Ganglia; Biogenic Monoamines; Callithrix; Caudate Nucleus; Dopamine; Enkephalin, Leucine; Enkephalin, Methionine; Female; Globus Pallidus; Homovanillic Acid; Male; Neuropeptides; Neurotensin; Putamen; Reference Values; Sincalide; Substance P | 1991 |
Preproenkephalin mRNA and methionine-enkephalin increase in mouse striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Enkephalins; G(M1) Ganglioside; Immunologic Techniques; Male; Mice; Mice, Inbred Strains; Nomifensine; Protein Precursors; RNA, Messenger; Selegiline | 1991 |
[Effects of monoamine oxidase B inhibitor and MPTP (1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine) on enkephalin levels in mice].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Methionine; Male; Mice; Phenethylamines; Radioimmunoassay; Selegiline | 1990 |
[Experimental research on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian animal models in the rhesus monkey and C57 black mouse].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Chemistry; Disease Models, Animal; Dopamine; Enkephalin, Leucine; Enkephalin, Methionine; Macaca mulatta; Male; Mice; Mice, Inbred C57BL; Parkinson Disease, Secondary; Substantia Nigra | 1990 |
Lack of change in basal ganglia neuropeptide content following subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of the common marmoset.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Behavior, Animal; Callitrichinae; Caudate Nucleus; Enkephalin, Leucine; Enkephalin, Methionine; Female; Homovanillic Acid; Male; Neuropeptides; Putamen; Pyridines; Sincalide; Substance P | 1986 |
Levels of Met-enkephalin, Leu-enkephalin, substance P and cholecystokinin in the brain of the common marmoset following long term 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine treatment.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Callitrichinae; Cholecystokinin; Dopamine; Enkephalin, Leucine; Enkephalin, Methionine; Female; Homovanillic Acid; Male; Organ Specificity; Pyridines; Reference Values; Substance P | 1988 |
Cellular localisation of enkephalin gene expression in MPTP-treated cynomolgus monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; DNA; Dopamine; Enkephalins; Female; Gene Expression Regulation; Macaca; Macaca fascicularis; Male; Neurotoxins; Nucleic Acid Hybridization; Parkinson Disease, Secondary; Pyridines | 1989 |
L-deprenyl in prevention of MPTP induced depletion of striatal enkephalins in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Disease Models, Animal; Enkephalin, Leucine; Enkephalin, Methionine; Male; Mice; Mice, Inbred C57BL; Parkinson Disease; Phenethylamines; Pyridines; Selegiline; Stereoisomerism | 1988 |
L-DOPA reverses altered gene expression of substance P but not enkephalin in the caudate-putamen of common marmosets treated with MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Callithrix; Caudate Nucleus; Enkephalins; Female; Gene Expression; In Situ Hybridization; Levodopa; Male; Mazindol; Motor Activity; Nucleus Accumbens; Putamen; RNA, Messenger; Substance P | 1995 |
Neurotrophic factor gene expression in astrocytes during development and following injury.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cells, Cultured; Enkephalin, Methionine; Enkephalins; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Male; Nerve Growth Factors; Nerve Tissue Proteins; Nucleic Acid Hybridization; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA; Substantia Nigra; Sympathectomy, Chemical | 1994 |
Striatal changes in preproenkephalin mRNA levels in parkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine; Enkephalins; Gene Expression; Histocytochemistry; In Situ Hybridization; Parkinson Disease, Secondary; Protein Precursors; Reference Values; RNA, Messenger; Saimiri | 1994 |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) effects on enkephalinergic neurons in various regions of mouse brain.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Enkephalins; Frontal Lobe; Homovanillic Acid; Kinetics; Male; Mice; Mice, Inbred C57BL; Neurons; Norepinephrine; Olfactory Pathways; Protein Precursors; RNA, Messenger | 1993 |
The expression of proenkephalin and prodynorphin genes and the induction of c-fos gene by dopaminergic drugs are not altered in the straitum of MPTP-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Autoradiography; Blotting, Northern; Dopamine; Dopamine Agents; Dopamine Agonists; Enkephalins; Gene Expression; Genes, fos; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Neostriatum; Protein Precursors; RNA, Messenger; Tyrosine 3-Monooxygenase | 1995 |
Dopaminergic regulation of peptide gene expression in the striatum of normal and parkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Dopamine; Dopamine Agents; Enkephalins; Gene Expression Regulation; Immunohistochemistry; Neostriatum; Neuropeptides; Parkinson Disease, Secondary; Protein Precursors; Saimiri; Tachykinins; Tyrosine 3-Monooxygenase | 1996 |
Preproenkephalin mRNA expression in the caudate-putamen of MPTP monkeys after chronic treatment with the D2 agonist U91356A in continuous or intermittent mode of administration: comparison with L-DOPA therapy.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aminoquinolines; Animals; Caudate Nucleus; Dopamine Agonists; Enkephalins; Female; Imidazoles; In Situ Hybridization; Levodopa; Macaca fascicularis; Ovariectomy; Parkinson Disease, Secondary; Protein Precursors; Putamen; Receptors, Dopamine D2; RNA, Messenger; Transcription, Genetic | 1997 |
Differential regulation of striatal preproenkephalin and preprotachykinin mRNA levels in MPTP-lesioned monkeys chronically treated with dopamine D1 or D2 receptor agonists.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Cabergoline; Corpus Striatum; Denervation; Dopamine Agents; Dopamine Agonists; Enkephalins; Ergolines; Female; Gene Expression; Macaca fascicularis; Movement Disorders; Protein Precursors; Pulsatile Flow; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Tachykinins | 1999 |
Striatal responses to partial dopaminergic lesion: evidence for compensatory sprouting.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine; Enkephalins; GAP-43 Protein; Gene Expression Regulation; Macaca nemestrina; Nerve Fibers; Protein Precursors; Reference Values; RNA, Messenger; Transcription, Genetic; Tyrosine 3-Monooxygenase | 2000 |
Striatal enkephalin gene expression does not reflect parkinsonian signs.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Cats; Caudate Nucleus; Corpus Striatum; Dopamine Agents; Enkephalins; Female; Gene Expression; Male; Motor Activity; Parkinson Disease; Parkinson Disease, Secondary; Protein Precursors; Recovery of Function; RNA, Messenger | 2000 |
Increases in striatal preproenkephalin gene expression are associated with nigrostriatal damage but not L-DOPA-induced dyskinesias in the squirrel monkey.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Corpus Striatum; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dyskinesias; Enkephalins; Female; Gene Expression Regulation; In Situ Hybridization; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Precursors; RNA, Messenger; Saimiri; Substantia Nigra; Time Factors | 2002 |
Naloxone reduces levodopa-induced dyskinesias and apomorphine-induced rotations in primate models of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benserazide; Callithrix; Dopamine; Dopamine Agents; Dopamine Antagonists; Dyskinesia, Drug-Induced; Enkephalins; Female; In Situ Hybridization; Levodopa; Male; Motor Activity; Naloxone; Narcotic Antagonists; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; RNA; Rotation; Stereotyped Behavior; Sympathectomy, Chemical | 2002 |
Pattern of levodopa-induced striatal changes is different in normal and MPTP-lesioned mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Binding, Competitive; Chronic Disease; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Enkephalins; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neural Pathways; Neurons; Parkinsonian Disorders; Protein Precursors; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Substantia Nigra; Tachykinins; Tyrosine 3-Monooxygenase | 2003 |
Compensatory regulation of striatal neuropeptide gene expression occurs before changes in metabolic activity of basal ganglia nuclei.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Corpus Striatum; Disease Models, Animal; Disease Progression; Electron Transport Complex IV; Enkephalins; Gene Expression Regulation; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Neuropeptides; Parkinsonian Disorders; Protein Precursors; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Tachykinins | 2003 |
Increased striatal pre-proenkephalin B expression is associated with dyskinesia in Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Aged, 80 and over; Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Enkephalins; Female; Humans; Macaca mulatta; Male; Parkinson Disease; Parkinsonian Disorders; Protein Precursors; RNA, Messenger | 2003 |
Regulation of dopamine receptor and neuropeptide expression in the basal ganglia of monkeys treated with MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Disease Models, Animal; Dopamine; Down-Regulation; Enkephalins; Female; Functional Laterality; Globus Pallidus; Macaca mulatta; Neostriatum; Neuropeptides; Parkinsonian Disorders; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance P; Substantia Nigra; Up-Regulation | 2004 |
Enhanced preproenkephalin-B-derived opioid transmission in striatum and subthalamic nucleus converges upon globus pallidus internalis in L-3,4-dihydroxyphenylalanine-induced dyskinesia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Antiparkinson Agents; Corpus Striatum; Drug Interactions; Dyskinesia, Drug-Induced; Enkephalins; Female; Gene Expression Regulation; In Situ Hybridization; Levodopa; Macaca fascicularis; Parkinsonian Disorders; Protein Precursors; Radioligand Assay; Receptors, Opioid; Regression Analysis; RNA, Messenger; Subthalamic Nucleus | 2007 |
Effect of estradiol on striatal dopamine activity of female hemiparkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Biogenic Amines; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enkephalins; Estradiol; Estrogens; Female; In Situ Hybridization; Iodine Radioisotopes; Macaca fascicularis; Ovariectomy; Parkinsonian Disorders; Protein Precursors; RNA, Messenger | 2009 |
Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Benzopyrans; Callithrix; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dyskinesia, Drug-Induced; Enkephalins; Female; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger | 2009 |
Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Age Factors; Animals; Animals, Newborn; Bromodeoxyuridine; Calbindins; Choline O-Acetyltransferase; Dopamine Agents; Dopamine and cAMP-Regulated Phosphoprotein 32; Doublecortin Domain Proteins; Dynorphins; Enkephalins; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neostriatum; Neurons; Neuropeptides; Nitric Oxide Synthase; Patch-Clamp Techniques; Rats; RNA, Messenger; S100 Calcium Binding Protein G; Tubulin; Tyrosine 3-Monooxygenase | 2011 |
Long-term treatment with l-DOPA and an mGlu5 receptor antagonist prevents changes in brain basal ganglia dopamine receptors, their associated signaling proteins and neuropeptides in parkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Basal Ganglia; Corpus Striatum; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Levodopa; Macaca fascicularis; MAP Kinase Signaling System; Parkinsonian Disorders; Protein Precursors; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger | 2014 |
Changes in the expression of genes encoding for mGlu4 and mGlu5 receptors and other regulators of the indirect pathway in acute mouse models of drug-induced parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acute Disease; Animals; Catalepsy; Corpus Striatum; Enkephalins; Haloperidol; Mice, Inbred C57BL; Mice, Knockout; Neurons; Parkinsonian Disorders; Protein Precursors; Proto-Oncogene Proteins c-fos; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Time Factors; Ventral Thalamic Nuclei | 2015 |
Effects of a combination treatment of KD5040 and
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dyskinesia, Drug-Induced; Enkephalins; Extracellular Signal-Regulated MAP Kinases; Levodopa; Magnoliopsida; Male; Mice, Inbred C57BL; Movement; Parkinson Disease; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-fos; Substance P | 2017 |