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enkephalin, d-penicillamine (2,5)- and dynorphins

enkephalin, d-penicillamine (2,5)- has been researched along with dynorphins in 67 studies

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-199012 (17.91)18.7374
1990's44 (65.67)18.2507
2000's8 (11.94)29.6817
2010's3 (4.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dziedzicka, M; Lasoń, W; Przewłocka, B; Przewłocki, R1
Gannon, RL; Terrian, DM1
Costa, M; Tonini, M; Waterman, SA1
Leslie, FM; Loughlin, SE; Smith, JA1
Bot, G; Brent, PJ; Chahl, LA; Johnston, PA1
Adler, MW; Geller, EB; Handler, CM1
Grider, JR; Makhlouf, GM1
Hattori, Y; Katafuchi, T; Koizumi, K1
Adams, JU; Holtzman, SG2
Bauer, AJ; Szurszewski, JH1
Gintzler, AR; Xu, H1
Kapoor, R; Willoughby, JO1
Crain, SM; Fan, SF; Shen, KF1
Gosnell, BA; Krahn, DD; Majchrzak, MJ1
Amerini, S; Ledda, F; Mantelli, L; Rubino, A1
Giuliani, S; Maggi, CA; Meli, A1
Han, JS; Wang, XH; Wang, XJ1
Herz, A; Shippenberg, TS; Spanagel, R1
Bird, ED; Crino, PB; Plager, MD; Vogt, BA1
Han, JS; Wang, XJ; Zhang, LJ1
Nunan, L; Porreca, F; Sheldon, RJ1
Gintzler, AR; Smolens, I; Xu, H1
Han, JS; Sun, SL1
Kirby, GC; McQueen, DS1
Burks, TF; Deupree, D; Hruby, V; Hsiao, S; Mosberg, HI; Porreca, F; Spencer, RL1
Harada, H; Misawa, H; Nozaki, M; Takagi, H; Ueda, H1
Bero, LA; Kuhn, CM; Lurie, SN1
Chavkin, C; Mailheau, S; Neumaier, JF1
Cowan, A; Mosberg, HI; Omnaas, JR; Porreca, F; Zhu, XZ1
Clark, JA; Houghten, R; Pasternak, GW1
Holtzman, SG; Ukai, M1
Fujiwara, M; Kurahashi, K; Okamoto, T1
Klitenick, MA; Wirtshafter, D1
Kuznetsov, A; Ma, GH; Miller, RJ; Philipson, LH1
Crain, SM; Shen, KF1
Angel, F; Baumann, R; Chamouard, P; Meyer, C; Rohr, S1
Kameyama, T; Toyoshi, T; Ukai, M2
Madamba, SG; Moore, SD; Schweitzer, P; Siggins, GR1
Macdonald, RL; Moises, HC; Rusin, KI1
Kameyama, T; Mizutani, M; Ukai, M1
Glaum, SR; Miller, RJ; Rhim, H1
Han, JS; Ren, MF; Wang, JF; Xue, JC1
Adamo, EB; Di Giovanni, G; Marini, R; Mulè, F; Postorino, A; Serio, R1
Kaneko, S; Katao, Y; Maekawa, K; Minami, M; Nakamura, S; Onogi, T; Satoh, M; Toya, T1
Bailey, EC; Bruce, DS; Hellgren, EC; Horton, ND; Jacobson, D; Oeltgen, PR; Setran, DP; Tramell, MS1
Giuliani, S; Lecci, A; Maggi, CA; Tramontana, M1
Hogenboom, F; Mulder, AH; Schoffelmeer, AN1
Grandy, DK; Murray, TF; Zhang, G1
Adams, DJ; Trequattrini, C1
Pierau, FK; Sann, H; Yakimova, KS1
Fujimoto, JM; Holmes, BB; Rady, JJ1
Környei, JL; Kovács, KA; Oszter, A; Rao, CV; Vértes, M; Vértes, Z1
Madamba, SG; Schweitzer, P; Siggins, GR1
Freeman, FM; Young, IG1
Boulter, J; Elgoyhen, AB; Glowatzki, E; Guth, PS; Holt, JC; Lioudyno, MI; Verbitsky, M; Zadina, JE1
Lunzer, MM; Portoghese, PS1
Bogacka, I; Kaminski, T; Okrasa, S; Przala, J; Siawrys, G1
Honda, E; Inenaga, K; Ono, K1
Bogacka, I; Kaminski, T; Okrasa, S; Przala, J; Siawrys, C1
Adler, MW; Chen, X; Geller, EB1
Adler, MW; Chen, X; Geller, EB; Rogers, TJ1
Celik, MÖ; Labuz, D; Machelska, H; Zimmer, A1
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A1
Artali, R; Calo, G; Cerlesi, MC; De Marco, R; Gentilucci, L; Janecka, A; Kluczyk, A; Perlikowska, R; Piekielna, J; Tömböly, C1
Adamska, A; Borics, A; Calo, G; Cerlesi, MC; Janecka, A; Kluczyk, A1

Other Studies

67 other study(ies) available for enkephalin, d-penicillamine (2,5)- and dynorphins

ArticleYear
Differential effects of opioid receptor agonists on nociception and cAMP level in the spinal cord of monoarthritic rats.
    Life sciences, 1992, Volume: 50, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Arthritis; Benzeneacetamides; Colforsin; Cyclic AMP; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanylyl Imidodiphosphate; Injections, Spinal; Male; Morphine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord

1992
Kappa opioid agonists inhibit transmitter release from guinea pig hippocampal mossy fiber synaptosomes.
    Neurochemical research, 1992, Volume: 17, Issue:8

    Topics: Animals; Azocines; Calcium; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Male; Potassium; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptosomes

1992
Modulation of peristalsis in the guinea-pig isolated small intestine by exogenous and endogenous opioids.
    British journal of pharmacology, 1992, Volume: 106, Issue:4

    Topics: Algorithms; Analgesics; Animals; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Muscle Contraction; Narcotics; Peristalsis; Receptors, Opioid

1992
kappa-Opioid inhibition of [3H]dopamine release from rat ventral mesencephalic dissociated cell cultures.
    Molecular pharmacology, 1992, Volume: 42, Issue:4

    Topics: Animals; Benzeneacetamides; Calcium; Cells, Cultured; Dopamine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Mesencephalon; Narcotics; Potassium; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrodotoxin

1992
Effects of intracerebroventricularly administered mu-, delta- and kappa-opioid agonists on locomotor activity of the guinea pig and the pharmacology of the locomotor response to U50,488H.
    Neuropharmacology, 1992, Volume: 31, Issue:9

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Guinea Pigs; Hypnotics and Sedatives; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Motor Activity; Narcotics; Peptide Fragments; Piloerection; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1992
Effect of mu-, kappa-, and delta-selective opioid agonists on thermoregulation in the rat.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4

    Topics: Amino Acid Sequence; Animals; Body Temperature; Body Temperature Regulation; Brain; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Injections, Intraventricular; Male; Molecular Sequence Data; Morphinans; Naltrexone; Narcotic Antagonists; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1992
Identification of opioid receptors on gastric muscle cells by selective receptor protection.
    The American journal of physiology, 1991, Volume: 260, Issue:1 Pt 1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sincalide; Stomach

1991
Characterization of opioid-sensitive neurons in the anteroventral third ventricle region of polydipsic inbred mice in vitro.
    Brain research, 1991, Jan-11, Volume: 538, Issue:2

    Topics: Angiotensin II; Animals; Cerebral Ventricles; Dose-Response Relationship, Drug; Drinking Behavior; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Hypothalamus; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Neurons; Peptide Fragments; Species Specificity

1991
Effects of receptor-selective opioids on operant behavior in morphine-treated and untreated rats.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:1

    Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Food; Infusions, Intravenous; Injections, Intraventricular; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid

1991
Effect of opioid peptides on circular muscle of canine duodenum.
    The Journal of physiology, 1991, Volume: 434

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Action Potentials; Animals; Dogs; Dose-Response Relationship, Drug; Duodenum; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Muscles; Neuromuscular Junction; Pyrrolidines; Receptors, Opioid

1991
Naltrexone-sensitizing effects of centrally administered morphine and opioid peptides.
    European journal of pharmacology, 1991, Jan-25, Volume: 193, Issue:1

    Topics: Animals; Conditioning, Operant; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta

1991
Opioids can produce a concentration-dependent naloxone-reversible enhancement of inhibition of evoked enkephalin release.
    NIDA research monograph, 1990, Volume: 105

    Topics: Analgesics; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; In Vitro Techniques; Myenteric Plexus; Naloxone; Narcotics; Parasympatholytics; Sufentanil; Thionucleotides; Virulence Factors, Bordetella

1990
Activation of mu opioid receptors in the pre-optic-anterior hypothalamus releases prolactin in the conscious male rat.
    Neuropeptides, 1991, Volume: 19, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anterior Hypothalamic Nucleus; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Preoptic Area; Prolactin; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, mu

1991
Opioids at low concentration decrease openings of K+ channels in sensory ganglion neurons.
    Brain research, 1991, Aug-30, Volume: 558, Issue:1

    Topics: Action Potentials; Animals; Dynorphins; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ganglia, Spinal; Narcotic Antagonists; Narcotics; Neurons, Afferent; Osmolar Concentration; Potassium Channels

1991
Effects of preferential delta and kappa opioid receptor agonists on the intake of hypotonic saline.
    Physiology & behavior, 1990, Volume: 47, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Drinking; Dynorphins; Eating; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Food Preferences; Hypotonic Solutions; Injections, Intraventricular; Male; Oligopeptides; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Taste

1990
Characterization of opioid receptors modulating the function of capsaicin-sensitive neurons in guinea-pig atria.
    European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic beta-Antagonists; Animals; Benzomorphans; Capsaicin; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Heart; Imidazoles; In Vitro Techniques; Male; Morphine; Neurons; Pyrrolidines; Receptors, Opioid; Reserpine

1990
Opioid receptors and prejunctional modulation of capsaicin-sensitive sensory nerves in guinea-pig left atrium.
    General pharmacology, 1990, Volume: 21, Issue:4

    Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Naloxone; Neurons, Afferent; Oligopeptides; Opioid Peptides; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, mu; Reserpine

1990
Cholecystokinin octapeptide antagonized opioid analgesia mediated by mu- and kappa- but not delta-receptors in the spinal cord of the rat.
    Brain research, 1990, Jul-16, Volume: 523, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Narcotic Antagonists; Pain; Pain Measurement; Peptide Fragments; Proglumide; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sincalide; Spinal Cord

1990
The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study.
    Journal of neurochemistry, 1990, Volume: 55, Issue:5

    Topics: Analgesics; Animals; Dialysis; Dopamine; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Magnesium; Male; Nucleus Accumbens; Peptide Fragments; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin

1990
Laminar distributions of muscarinic acetylcholine, serotonin, GABA and opioid receptors in human posterior cingulate cortex.
    Neuroscience, 1990, Volume: 36, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Autoradiography; Cerebral Cortex; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Humans; Iodocyanopindolol; Ketanserin; Male; Middle Aged; Oxotremorine; Paroxetine; Pindolol; Piperidines; Pirenzepine; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Opioid; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1990
Phorbol ester suppression of opioid analgesia in rats.
    Life sciences, 1990, Volume: 47, Issue:19

    Topics: Analgesia; Animals; Calcium; Cyclic AMP; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Narcotic Antagonists; Peptide Fragments; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Spinal Cord; Tetradecanoylphorbol Acetate

1990
Differential modulation by [D-Pen2, D-Pen5]enkephalin and dynorphin A-(1-17) of the inhibitory bladder motility effects of selected mu agonists in vivo.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Analgesics; Animals; Drug Synergism; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Female; Morphine; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex; Urinary Bladder

1989
Opioids can enhance and inhibit the electrically evoked release of methionine-enkephalin.
    Brain research, 1989, Dec-11, Volume: 504, Issue:1

    Topics: Action Potentials; Animals; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Myenteric Plexus; Naloxone; Sufentanil

1989
[High and low frequency electroacupuncture analgesia are mediated by different types of opioid receptors at spinal level: a cross tolerance study].
    Sheng li xue bao : [Acta physiologica Sinica], 1989, Volume: 41, Issue:4

    Topics: Acupuncture Analgesia; Analgesics; Animals; Dynorphins; Electroacupuncture; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Peptide Fragments; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Spinal Cord

1989
Characterization of opioid receptors in the cat carotid body involved in chemosensory depression in vivo.
    British journal of pharmacology, 1986, Volume: 88, Issue:4

    Topics: Animals; Carotid Body; Cats; Chemoreceptor Cells; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hypercapnia; Hypoxia; Peptide Fragments; Receptors, Opioid

1986
Centrally-administered opioid selective agonists inhibit drinking in the rat.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Brain; Cyclazocine; Drinking Behavior; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Male; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Rats; Receptors, Opioid

1986
Purified opioid mu-receptor is of a different molecular size than delta- and kappa-receptors.
    Neuroscience letters, 1987, Apr-10, Volume: 75, Issue:3

    Topics: Animals; Brain Chemistry; Chemical Phenomena; Chemistry; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ligands; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1987
Early ontogeny of kappa-opioid receptor regulation of prolactin secretion in the rat.
    Brain research, 1987, Dec-15, Volume: 465, Issue:1-2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hydrazines; Morphine; Peptide Fragments; Prolactin; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin

1987
Opioid receptor-mediated responses in the dentate gyrus and CA1 region of the rat hippocampus.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GABA Antagonists; Hippocampus; Interneurons; Naloxone; Oligopeptides; Rats; Receptors, Opioid

1988
Direct dependence studies in rats with agents selective for different types of opioid receptor.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: Analgesics; Animals; Behavior, Animal; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance-Related Disorders

1988
Opiate binding in calf thalamic membranes: a selective mu 1 binding assay.
    Molecular pharmacology, 1988, Volume: 34, Issue:3

    Topics: Animals; Cattle; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thalamus

1988
Effects of intrahypothalamic administration of opioid peptides selective for mu-, kappa, and delta-receptors on different schedules of water intake in the rat.
    Brain research, 1988, Sep-06, Volume: 459, Issue:2

    Topics: Animals; Drinking Behavior; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Microinjections; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Saline Solution, Hypertonic; Time Factors

1988
Effects of naloxone and opioid agonists on gastric excitatory responses to stimulation of the vagus nerve in cats.
    British journal of pharmacology, 1988, Volume: 95, Issue:2

    Topics: Animals; Cats; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Male; Naloxone; Narcotic Antagonists; Narcotics; Peptide Fragments; Stomach; Vagus Nerve

1988
Behavioral and neurochemical effects of opioids in the paramedian midbrain tegmentum including the median raphe nucleus and ventral tegmental area.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:1

    Topics: Animals; Brain Chemistry; Dopamine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Feeding Behavior; Male; Morphine; Motor Activity; Naloxone; Neurotransmitter Agents; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Ventral Tegmental Area

1995
kappa-Opioid receptor activates an inwardly rectifying K+ channel by a G protein-linked mechanism: coexpression in Xenopus oocytes.
    Molecular pharmacology, 1995, Volume: 47, Issue:5

    Topics: Animals; Benzeneacetamides; Cloning, Molecular; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Gene Expression; GTP-Binding Proteins; In Vitro Techniques; Mice; Naloxone; Naltrexone; Oocytes; Pertussis Toxin; Potassium Channels; Pyrrolidines; Receptors, Opioid, kappa; RNA, Complementary; Virulence Factors, Bordetella; Xenopus

1995
Specific N- or C-terminus modified dynorphin and beta-endorphin peptides can selectively block excitatory opioid receptor functions in sensory neurons and unmask potent inhibitory effects of opioid agonists.
    Brain research, 1995, Feb-27, Volume: 673, Issue:1

    Topics: Action Potentials; Animals; beta-Endorphin; Cells, Cultured; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ganglia, Spinal; Mice; Morphine; Neurons; Receptors, Opioid, delta

1995
Delta-opioid receptor agonists inhibit neuromuscular transmission in human colon.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: Analgesics; Analgesics, Opioid; Colon; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Gastrointestinal Motility; Humans; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Neuromuscular Junction; Peptide Fragments; Receptors, Opioid, delta; Synaptic Transmission

1994
Receptor-selective opioid peptides fail to affect behavioral responses induced by a low dose of apomorphine in the mouse.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:3

    Topics: Analgesics; Animals; Apomorphine; Behavior, Animal; Benzazepines; Dopamine Agents; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Grooming; Male; Mice; Mice, Inbred Strains; Motor Activity; Peptide Fragments; Receptors, Opioid; Stereotyped Behavior

1993
Voltage-dependent effects of opioid peptides on hippocampal CA3 pyramidal neurons in vitro.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Barium Compounds; Cadmium; Carbachol; Chlorides; Computer Simulation; Dynorphins; Electrophysiology; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Models, Neurological; Naloxone; Narcotics; Neurons; Pyramidal Tracts; Pyrrolidines; Rats; Rats, Sprague-Dawley

1994
Mu- and kappa-opioid receptors selectively reduce the same transient components of high-threshold calcium current in rat dorsal root ganglion sensory neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:10

    Topics: Analgesics; Animals; Benzeneacetamides; Calcium; Calcium Channels; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Naloxone; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Pyrrolidines; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reference Values; Sensitivity and Specificity

1994
Opioid peptides selective for receptor types modulate cocaine-induced behavioral responses in mice.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1994, Volume: 14, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Naltrexone; Opioid Peptides

1994
Selective opioid agonists modulate afferent transmission in the rat nucleus tractus solitarius.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Action Potentials; Afferent Pathways; Analgesics; Animals; Benzeneacetamides; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Medulla Oblongata; Potassium Channels; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Synaptic Transmission

1993
Cyclic AMP mediates mu and delta, but not kappa opioid analgesia in the spinal cord of the rat.
    Life sciences, 1993, Volume: 52, Issue:24

    Topics: Analgesia; Analgesics; Animals; Bucladesine; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Morphine; Pain; Peptide Fragments; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Time Factors

1993
Modulation of non-adrenergic non-cholinergic inhibitory transmission in rat duodenum: role of opiates and 5-hydroxytryptamine.
    Archives italiennes de biologie, 1993, Volume: 131, Issue:2-3

    Topics: Analgesics; Animals; Atropine; Autonomic Nervous System; Duodenum; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gastrointestinal Motility; Guanethidine; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Rats; Rats, Wistar; Serotonin; Synaptic Transmission; Tetrodotoxin

1993
Cloning and expression of a cDNA for the rat kappa-opioid receptor.
    FEBS letters, 1993, Aug-30, Volume: 329, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Analgesics; Animals; Base Sequence; Cells, Cultured; Cloning, Molecular; DNA; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Molecular Sequence Data; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Sequence Homology, Amino Acid

1993
Intrastriatal injection of opioid receptor agonists inhibits apomorphine-induced behavior in 6-hydroxydopamine-treated mice.
    European journal of pharmacology, 1995, Dec-29, Volume: 294, Issue:2-3

    Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Naltrexone; Oxidopamine; Peptide Fragments; Receptors, Opioid

1995
Circannual variations in bear plasma albumin and its opioid-like effects on guinea pig ileum.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:4

    Topics: Analgesics; Animals; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Hibernation; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Seasons; Serum Albumin; Ursidae

1996
Role of kappa opioid receptors in modulating cholinergic twitches in the circular muscle of guinea-pig colon.
    British journal of pharmacology, 1996, Volume: 119, Issue:5

    Topics: Acetylcholine; Animals; Colon; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Oligopeptides; Opioid Peptides; Receptors, Cholinergic; Receptors, Opioid, kappa

1996
Kappa1- and kappa2-opioid receptors mediating presynaptic inhibition of dopamine and acetylcholine release in rat neostriatum.
    British journal of pharmacology, 1997, Volume: 122, Issue:3

    Topics: Acetylcholine; Animals; Benzeneacetamides; Dopamine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; N-Methylaspartate; Naloxone; Neostriatum; Neural Inhibition; Peptide Fragments; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1997
Orphanin FQ has an inhibitory effect on the guinea pig ileum and the mouse vas deferens.
    Brain research, 1997, Oct-24, Volume: 772, Issue:1-2

    Topics: Animals; CHO Cells; Cricetinae; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Muscle, Smooth; Nociceptin; Opioid Peptides; Peptide Fragments; Receptors, Opioid; Vas Deferens

1997
Opioid receptor-mediated inhibition of omega-conotoxin GVIA-sensitive calcium channel currents in rat intracardiac neurons.
    Journal of neurophysiology, 1998, Volume: 79, Issue:2

    Topics: Acetylcholine; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Benzomorphans; Calcium; Calcium Channels; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Heart Conduction System; Ion Channel Gating; Ion Transport; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; omega-Conotoxin GVIA; Parasympathetic Nervous System; Patch-Clamp Techniques; Peptides; Pertussis Toxin; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Virulence Factors, Bordetella

1998
Effects of kappa and delta opioid agonists on activity and thermosensitivity of rat hypothalamic neurons.
    Brain research, 1998, Mar-09, Volume: 786, Issue:1-2

    Topics: Animals; Dynorphins; Electrophysiology; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hypothalamus; Hypothalamus, Anterior; In Vitro Techniques; Male; Neurons; Preoptic Area; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thermosensing

1998
Antianalgesic action of dynorphin A mediated by spinal cholecystokinin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 220, Issue:3

    Topics: Analgesia; Analgesics; Animals; Antibodies; Cholecystokinin; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indoles; Injections, Spinal; Male; Meglumine; Mice; Morphine; Proglumide; Receptors, Cholecystokinin; Receptors, Opioid, delta; Spinal Cord

1999
Opioid peptides inhibit the action of oestradiol on human myometrial cells in culture.
    Molecular human reproduction, 1999, Volume: 5, Issue:6

    Topics: Adult; Cell Division; Cells, Cultured; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Estradiol; Female; Humans; Inhibitory Concentration 50; Muscle, Smooth; Myometrium; Naloxone; Narcotic Antagonists; Progesterone

1999
Dynorphin selectively augments the M-current in hippocampal CA1 neurons by an opiate receptor mechanism.
    Journal of neurophysiology, 1999, Volume: 82, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Hippocampus; In Vitro Techniques; Oligopeptides; Peptide Fragments; Potassium Channels; Pyramidal Cells; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa

1999
Identification of the opioid receptors involved in passive-avoidance learning in the day-old chick during the second wave of neuronal activity.
    Brain research, 2000, May-12, Volume: 864, Issue:2

    Topics: Age Factors; Amnesia; Analgesics, Opioid; Animals; Anisomycin; Avoidance Learning; Brain Chemistry; Chickens; Chloramphenicol; Conditioning, Psychological; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Female; Male; Memory; Naltrexone; Narcotic Antagonists; Neurons; Nociceptin; Oligopeptides; Opioid Peptides; Protein Synthesis Inhibitors; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vasodilator Agents

2000
The alpha9/alpha10-containing nicotinic ACh receptor is directly modulated by opioid peptides, endomorphin-1, and dynorphin B, proposed efferent cotransmitters in the inner ear.
    Molecular and cellular neurosciences, 2002, Volume: 20, Issue:4

    Topics: Acetylcholine; Animals; Anura; Cochlea; Dynorphins; Ear, Inner; Electric Conductivity; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Hair Cells, Auditory; In Vitro Techniques; Narcotic Antagonists; Neurotransmitter Agents; Oligopeptides; Oocytes; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Saccule and Utricle; Synapses; Xenopus laevis

2002
Identity of the putative delta1-opioid receptor as a delta-kappa heteromer in the mouse spinal cord.
    European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3

    Topics: Animals; Benzylidene Compounds; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Immune Sera; Mice; Naltrexone; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord

2003
The regulation of steroidogenesis by opioid peptides in porcine theca cells.
    Animal reproduction science, 2003, Sep-15, Volume: 78, Issue:1-2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; beta-Endorphin; Cells, Cultured; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Estradiol; Female; Opioid Peptides; Progesterone; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Steroids; Swine; Testosterone; Theca Cells

2003
DAMGO suppresses both excitatory and inhibitory synaptic transmission in supraoptic neurones of mouse hypothalamic slice preparations.
    Journal of neuroendocrinology, 2004, Volume: 16, Issue:3

    Topics: Analgesics, Opioid; Animals; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Male; Mice; Mice, Inbred ICR; Neural Inhibition; Neurons; Oligopeptides; Organ Culture Techniques; Patch-Clamp Techniques; Receptors, Opioid; Supraoptic Nucleus

2004
The influence of opioid peptides on steroidogenesis in porcine granulosa cells.
    Reproduction in domestic animals = Zuchthygiene, 2004, Volume: 39, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Granulosa Cells; Luteinizing Hormone; Opioid Peptides; Ovarian Follicle; Swine

2004
Nociceptin/orphanin FQ blocks the antinociception induced by mu, kappa and delta opioid agonists on the cold water tail-flick test.
    European journal of pharmacology, 2007, Feb-14, Volume: 557, Issue:1

    Topics: Analgesics, Opioid; Animals; Cold Temperature; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Male; Morphine; Nociceptin; Opioid Peptides; Pain; Pain Measurement; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tail; Water

2007
The chemokine CX3CL1/fractalkine interferes with the antinociceptive effect induced by opioid agonists in the periaqueductal grey of rats.
    Brain research, 2007, Jun-11, Volume: 1153

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Chemokine CX3CL1; Drug Interactions; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Male; Pain Measurement; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid

2007
Distinct roles of exogenous opioid agonists and endogenous opioid peptides in the peripheral control of neuropathy-triggered heat pain.
    Scientific reports, 2016, 09-08, Volume: 6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; beta-Endorphin; Corticotropin-Releasing Hormone; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Hot Temperature; Male; Mice, Inbred C57BL; Mice, Knockout; Neuralgia; Opioid Peptides; Peripheral Nervous System; Receptors, Opioid

2016
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
    NIDA research monograph, 1998, Volume: 178

    Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders

1998
Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration.
    European journal of medicinal chemistry, 2016, Feb-15, Volume: 109

    Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; CHO Cells; Cricetulus; Guinea Pigs; Male; Mice; Molecular Docking Simulation; Oligopeptides; Pain; Peptides, Cyclic; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship

2016
Synthesis, biological evaluation and structural analysis of novel peripherally active morphiceptin analogs.
    Bioorganic & medicinal chemistry, 2016, Apr-01, Volume: 24, Issue:7

    Topics: Animals; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Endorphins; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship

2016