enkephalin, d-penicillamine (2,5)- and 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide

enkephalin, d-penicillamine (2,5)- has been researched along with 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (25.00)	18.2507
2000's	15 (62.50)	29.6817
2010's	3 (12.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chadderdon, AM; Deschamps, JR; Hassan, SA; Jacobson, AE; Katz, JL; Kopajtic, TA; Lee, YS; Rice, KC; Traynor, JR; Truong, PM	1
Calderon, SN; De Leon, IA; Knapp, RJ; Landsman, R; Malatynska, E; Nagase, H; Rice, K; Santoro, G; Varga, E; Waite, S	1
Loew, GH; Maguire, PA	1
Burkey, TH; Hosohata, K; Hosohata, Y; Hruby, VJ; Knapp, RJ; Nagase, H; Porreca, F; Quock, RM; Rice, KC; Roeske, WR; Yamamura, HI; Zhang, X	1
Broccardo, M; Improta, G; Tabacco, A	1
Clapp, JF; Kett, A; Kim, H; Olariu, N; Soong, Y; Szeto, HH; Wu, D	1
Benjamin, D; Pohorecky, LA; Rice, KC; Skiandos, A; Zhang, X	1
Burkey, TH; Cowell, SM; Hruby, VJ; Okura, T; Roeske, WR; Varga, E; Yamamura, HI	1
Burkey, TH; Hosohata, Y; Hruby, VJ; Kovelowski, CJ; Lai, J; Ossipov, MH; Porreca, F; Rice, KC; Roeske, WR; Sora, I; Uhl, GR; Vanderah, TW; Yamamura, HI; Zhang, X	1
Boyd, RE; Carson, JR; Codd, EE; Gauthier, AD; Neilson, LA; Zhang, SP	1
Akil, H; Bonner, G; Meng, F	1
Hosohata, Y; Hruby, VJ; Knapp, RJ; Li, X; Nagase, H; Rice, KC; Roeske, WR; Stropova, D; Varga, EV; Yamamura, HI	1
Alt, A; Clark, MJ; Traynor, JR; Woods, JH	1
Broom, DC; Nitsche, JF; Pintar, JE; Rice, KC; Traynor, JR; Woods, JH	1
Cowell, SM; Hosohata, Y; Hruby, VJ; Nagase, H; Navratilova, E; Okura, T; Rice, K; Roeske, WR; Varga, EV; Yamamura, HI	1
Brown, DR; Townsend, DW	1
Jambrosic, JC; Navratilova, E; Roeske, WR; Stropova, D; Varga, EV; Yamamura, HI	1
Beck, H; Hans, M; Remy, C; Remy, S; Swandulla, D	1
Planas, E; Pol, O; Poveda, R; Puig, MM; Romero, A; Sánchez, S	1
Booze, RM; Dodson, SL; Nath, A; Wallace, DR	1
Bosse, KE; Gnegy, ME; Jutkiewicz, EM; Traynor, JR	1
Benaderet, TS; Bishop-Mathis, K; Dersch, CM; Partilla, JS; Prisinzano, TE; Rothman, RB; Simpson, DS; Wang, X; Xu, H	1
Balboni, G; Charfi, I; Mnie-Filali, O; Nagi, K; Pineyro, G; Schiller, PW; Thibault, D; Trudeau, LE	1
Leánez, S; McDonnell, C; Pol, O	1

Other Studies

24 other study(ies) available for enkephalin, d-penicillamine (2,5)- and 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide

Article	Year
Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study. Bioorganic & medicinal chemistry, 2017, 04-15, Volume: 25, Issue:8 Topics: Carbon-13 Magnetic Resonance Spectroscopy; Computer Simulation; Crystallography, X-Ray; Models, Molecular; Molecular Dynamics Simulation; Morphinans; Protein Binding; Proton Magnetic Resonance Spectroscopy; Receptors, Opioid; Spectrometry, Mass, Electrospray Ionization	2017
Efficacy of peptide and nonpeptidic agonists at the cloned human delta opioid receptor. Proceedings of the Western Pharmacology Society, 1995, Volume: 38 Topics: Analgesics; Animals; Benzamides; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Opioid Peptides; Piperazines; Quinolines; Receptors, Opioid, delta; Recombinant Proteins	1995
Thermodynamics of ligand binding to the cloned delta-opioid receptor. European journal of pharmacology, 1996, Dec-30, Volume: 318, Issue:2-3 Topics: Animals; Benzamides; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Mice; Oligopeptides; Piperazines; Receptors, Opioid, delta; Recombinant Proteins; Thermodynamics	1996
Relative efficacies of delta-opioid receptor agonists at the cloned human delta-opioid receptor. European journal of pharmacology, 1997, May-12, Volume: 326, Issue:1 Topics: Animals; Benzamides; CHO Cells; Cloning, Molecular; Cricetinae; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Naltrexone; Narcotic Antagonists; Piperazines; Quinolines; Receptors, Opioid, delta; Sulfur Radioisotopes	1997
Central effect of SNC 80, a selective and systemically active delta-opioid receptor agonist, on gastrointestinal propulsion in the mouse. European journal of pharmacology, 1998, Jan-26, Volume: 342, Issue:2-3 Topics: Animals; Benzamides; Central Nervous System; Colon; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gastrointestinal Motility; Injections, Intraperitoneal; Male; Mice; Narcotic Antagonists; Piperazines; Receptors, Opioid, delta; Receptors, sigma	1998
Respiratory depression after intravenous administration of delta-selective opioid peptide analogs. Peptides, 1999, Volume: 20, Issue:1 Topics: Analgesics; Animals; Benzamides; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Injections, Intravenous; Piperazines; Pregnancy; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiratory Physiological Phenomena; Sheep	1999
Effect of chronic social stress on delta-opioid receptor function in the rat. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1 Topics: Adrenal Glands; Agonistic Behavior; Analgesia; Animals; Benzamides; Body Temperature; Body Weight; Brain; Catecholamines; Chronic Disease; Corticosterone; Defecation; Dominance-Subordination; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Motor Activity; Piperazines; Rats; Rats, Long-Evans; Receptors, Opioid, delta; Social Environment; Stress, Psychological	1999
Differential down-regulation of the human delta-opioid receptor by SNC80 and [D-Pen(2),D-Pen(5)]enkephalin. European journal of pharmacology, 2000, Jan-10, Volume: 387, Issue:2 Topics: Benzamides; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Humans; Naltrexone; Piperazines; Receptors, Opioid, delta	2000
delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice. European journal of pharmacology, 2000, Feb-04, Volume: 388, Issue:3 Topics: Analgesics, Opioid; Animals; Benzamides; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Membranes; Mice; Mice, Knockout; Oligopeptides; Pain Measurement; Piperazines; Protein Binding; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord	2000
Synthesis and binding affinities of 4-diarylaminotropanes, a new class of delta opioid agonists. Bioorganic & medicinal chemistry letters, 2000, May-15, Volume: 10, Issue:10 Topics: Animals; Benzamides; Binding Sites; Diphenylamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Morphine; Piperazines; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship; Tropanes	2000
Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop. European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2 Topics: Amino Acid Substitution; Animals; Benzamides; Benzomorphans; Binding Sites; Binding, Competitive; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Piperazines; Protein Conformation; Radioligand Assay; Rats; Receptors, Opioid, mu; Signal Transduction; Sulfur Radioisotopes	2000
Mutation W284L of the human delta opioid receptor reveals agonist specific receptor conformations for G protein activation. Life sciences, 2001, Apr-06, Volume: 68, Issue:19-20 Topics: Animals; Benzamides; Binding Sites; CHO Cells; Cricetinae; DNA Primers; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Indoles; Intracellular Membranes; Isoquinolines; Morpholines; Mutagenesis, Site-Directed; Naltrexone; Piperazines; Point Mutation; Protein Conformation; Quinolines; Receptors, Opioid, delta; Sulfur Radioisotopes	2001
Mu and Delta opioid receptors activate the same G proteins in human neuroblastoma SH-SY5Y cells. British journal of pharmacology, 2002, Volume: 135, Issue:1 Topics: Adenylyl Cyclases; Analgesics, Opioid; Benzamides; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Neuroblastoma; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu; Sulfur Radioisotopes; Tumor Cells, Cultured	2002
Comparison of receptor mechanisms and efficacy requirements for delta-agonist-induced convulsive activity and antinociception in mice. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:2 Topics: Analgesics; Analgesics, Opioid; Animals; Benzamides; Benzylidene Compounds; Convulsants; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Male; Mice; Mice, Knockout; Naltrexone; Narcotic Antagonists; Piperazines; Receptors, Opioid, delta	2002
Agonist-specific down-regulation of the human delta-opioid receptor. European journal of pharmacology, 2003, Jan-10, Volume: 459, Issue:1 Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Benzamides; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Humans; Molecular Sequence Data; Naltrexone; Pertussis Toxin; Phosphorylation; Piperazines; Radioligand Assay; Receptors, Opioid, delta; Recombinant Fusion Proteins; Sequence Deletion; Tritium	2003
Pharmacological characterization of a 7-benzylidenenaltrexone-preferring opioid receptor in porcine ileal submucosa. British journal of pharmacology, 2003, Volume: 140, Issue:4 Topics: Amphibian Proteins; Animals; Anions; Benzamides; Benzylidene Compounds; Biological Transport, Active; Carrier Proteins; Diprenorphine; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Gastrointestinal Motility; Ileum; Intestinal Mucosa; Male; Naltrexone; Neurons, Afferent; Oligopeptides; Piperazines; Quinolines; Receptors, Opioid, delta; Receptors, Opioid, mu; Swine; Tritium	2003
Mutation S363A in the human delta-opioid receptor selectively reduces down-regulation by a peptide agonist. European journal of pharmacology, 2004, Feb-06, Volume: 485, Issue:1-3 Topics: Alanine; Amino Acid Substitution; Benzamides; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Humans; Mutation; Piperazines; Receptors, Opioid, delta; Serine	2004
Modulation of voltage-dependent sodium channels by the delta-agonist SNC80 in acutely isolated rat hippocampal neurons. Neuropharmacology, 2004, Volume: 47, Issue:7 Topics: Algorithms; Analgesics, Opioid; Animals; Benzamides; Enkephalin, D-Penicillamine (2,5)-; Hippocampus; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Piperazines; Rats; Rats, Wistar; Receptors, Opioid, delta; Sodium Channels	2004
Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw. European journal of pharmacology, 2005, Mar-28, Volume: 511, Issue:2-3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Capsaicin; Carrageenan; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enkephalin, D-Penicillamine (2,5)-; Extravasation of Diagnostic and Therapeutic Materials; Fentanyl; Hindlimb; Histamine Antagonists; Inflammation; Male; Morphine; Narcotic Antagonists; Oxidopamine; p-Methoxy-N-methylphenethylamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2005
Delta opioid agonists attenuate TAT(1-72)-induced oxidative stress in SK-N-SH cells. Neurotoxicology, 2006, Volume: 27, Issue:1 Topics: Benzamides; Cell Line, Tumor; Cell Membrane; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Fluoresceins; Free Radicals; Gene Products, tat; Humans; Molsidomine; Naltrexone; Narcotic Antagonists; Opioid Peptides; Oxidative Stress; Piperazines; Receptors, Opioid, delta; tat Gene Products, Human Immunodeficiency Virus	2006
The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum. Neuropharmacology, 2008, Volume: 55, Issue:5 Topics: Amphetamine; Analgesics, Opioid; Analysis of Variance; Animals; Area Under Curve; Benzamides; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Male; Naltrexone; Narcotic Antagonists; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Subcellular Fractions; Time Factors; Tritium	2008
Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors. Brain research bulletin, 2008, Sep-05, Volume: 77, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzamides; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Diterpenes, Clerodane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Female; Furans; Gene Expression; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Morphine; Oligopeptides; Piperazines; Pyrones; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2008
Ligand- and cell-dependent determinants of internalization and cAMP modulation by delta opioid receptor (DOR) agonists. Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:8 Topics: Analysis of Variance; Benzamides; Benzimidazoles; Blotting, Western; Chronic Pain; Cyclic AMP; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Fluorescent Antibody Technique; G-Protein-Coupled Receptor Kinase 2; Green Fluorescent Proteins; HEK293 Cells; Humans; Ligands; Neurons; Oligopeptides; Piperazines; Receptors, Opioid, delta	2014
The induction of the transcription factor Nrf2 enhances the antinociceptive effects of delta-opioid receptors in diabetic mice. PloS one, 2017, Volume: 12, Issue:7 Topics: Animals; Benzamides; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Enkephalin, D-Penicillamine (2,5)-; Hyperalgesia; Isothiocyanates; Male; Mice; NF-E2-Related Factor 2; Piperazines; Receptors, Opioid, delta; Sulfoxides	2017