endothelin-1 has been researched along with emoxypine-succinate* in 1 studies
1 other study(ies) available for endothelin-1 and emoxypine-succinate
| Article | Year |
|---|---|
[Effects of mexidol and sulodexide on the level of specific markers of endothelial dysfunction in animals with experimental diabetes mellitus].
Streptozotocin-induced diabetes leads to the development of endothelial dysfunction, as evidenced by decreased expression of endothelial nitric oxide synthase (eNOS) and increased expression of endothelin-1 as specific markers of endothelial disorders. All test substances showed endotelioprotective activity by increasing the concentration of eNOS and reducing the level of endothelin-1. With respect to the degree of impact on the eNOS and endothelin-1 levels, the compounds studied can be rated as follows: sulodexide > meksidol. Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Endothelin-1; Endothelium; Glycosaminoglycans; Immunohistochemistry; Male; Nitric Oxide Synthase Type III; Picolines; Rats; Vascular Diseases | 2012 |