emtricitabine has been researched along with racivir in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 22 (70.97) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cannon, D; Furman, PA; Lloyd, RM; Mathis, R; McMillan, A; Peck, A; Schinazi, RF; Sommadossi, JP; St Clair, M; Wilson, J | 1 |
| Peck, A; Schinazi, RF; Sommadossi, JP | 1 |
| Davis, M; Dornsife, RE; Frick, LW; Furman, PA; Fyfe, JA; Liotta, DC; Nelson, DJ; Paff, M; Wilson, LJ; Wurster, JA | 1 |
| Boudinot, FD; Ibrahim, SS; Liotta, DC; Manning, C; McClure, HM; Schinazi, RF | 1 |
| Leibowitch, J; Liotta, DC; Mathez, D; Schinazi, RF | 1 |
| Condreay, LD; Daluge, SM; Ellis, MN; Furman, PA; Jansen, RW; Johnson, LC; Paff, MT; Painter, GR; Powdrill, TF; Selleseth, DW | 1 |
| Lacey, SF; Larder, BA | 1 |
| Bazmi, HZ; Cannon, DL; Chu, CK; Ilksoy, N; Liotta, DC; Lloyd, RM; McMillan, A; Mellors, JW; Nguyen, MH; Schinazi, RF | 1 |
| Borroto-Esoda, K; Furman, PA; Hopkins, S; Liotta, DC; Martin, JL; Painter, G; Wilson, JE | 1 |
| Frick, LW; Lambe, CU; Nelson, DJ; St John, L; Taylor, LC | 1 |
| Aldrich, CE; Averett, DR; Cullen, JM; Fourel, I; Mason, WS; Pugh, J; Saputelli, J; Schaffer, P | 1 |
| Averett, DR; Miller, WH; Nelson, DJ; Paff, MT; Prus, KL | 1 |
| Abobo, CV; Boudinot, FD; Liotta, DC; Ni, L; Schinazi, RF | 1 |
| Frick, LW; Furfine, ES; Furman, PA; Liotta, DC; Nelson, DJ; Painter, GR; St John, L; Taylor, LC | 1 |
| Averett, DR; Jansen, RW; Johnson, LC | 1 |
| Aulabaugh, AE; Boone, LR; Boyd, FL; Daluge, SM; Davis, MG; Freeman, GA; Miller, WH; Painter, GR; VanDraanen, NA; Wilson, JE | 1 |
| Averett, DR; Condreay, JP; Condreay, LD; Jansen, RW; Paff, MT | 1 |
| Farrant, RD; Frick, LW; Lindon, JC; Sanderson, PN; Shockcor, JP; Sweatman, BC; Wurm, RM | 1 |
| Lloyd, RM; North, TW; Remington, KM; Schinazi, RF; Smith, RA | 1 |
| Biron, K; Botteron, C; Cecchi, A; Cullen, JM; Davis, MG; Dunn, SE; Frick, L; Goulding, A; Linsey, D; Linzey, D; Paff, MT; Smith, SL | 1 |
| Aldrich, CE; Averett, D; Condreay, L; Mason, WS; Moraleda, G; Saputelli, J | 1 |
| Anderson, KS; Feng, JY; Schinazi, RF; Shi, J | 1 |
| Chan, HL; Lau, TC; Leung, NW; Sung, JJ; Wong, ML | 1 |
| Otto, MJ | 1 |
| Carruth, LM; Clements, JE; Li, M; Mankowski, JL; Miller, MD; Queen, LA; Shen, A; Siliciano, RF; Tarwater, PM; Zink, MC | 1 |
| Hurwitz, SJ; Otto, MJ; Schinazi, RF | 1 |
| Arastèh, K; Beard, A; Cartee, L; Drauz, D; Herzmann, C; Kreckel, P; Murphy, RL; Otto, MJ; Schinazi, RF; Schulbin, H | 1 |
| Nelson, MR; Waters, L | 1 |
| Dandekar, S; Sankaran, S; Verhoeven, D | 1 |
| Abuin, A; Cucoranu, I; Fields, E; Green, E; Hosseini, SH; Hoying, A; Ivey, K; Kohler, JJ; Lavie, A; Lewis, W; Raper, CM; Russ, R; Santoianni, R; Yang, Q; Zhelyabovska, O | 1 |
| Amancha, PK; Ansari, AA; Hong, JJ; Rogers, K; Villinger, F | 1 |
2 review(s) available for emtricitabine and racivir
| Article | Year |
|---|---|
New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections.
Topics: Animals; Anti-HIV Agents; Clinical Trials as Topic; Cytidine Triphosphate; Deoxycytidine; Dideoxynucleosides; Dioxolanes; Emtricitabine; HIV Infections; Humans; Purine Nucleosides; Reverse Transcriptase Inhibitors; Thionucleosides; Zalcitabine | 2004 |
New drugs.
Topics: Anti-HIV Agents; Benzophenones; Cytidine Triphosphate; Darunavir; Deoxycytidine; Emtricitabine; HIV; HIV Fusion Inhibitors; HIV Reverse Transcriptase; Humans; Imidazoles; Nitriles; Protease Inhibitors; Pyridazines; Pyridines; Pyrimidines; Pyrones; Reverse Transcriptase Inhibitors; Sulfonamides; Sulfur Compounds; Zalcitabine | 2005 |
4 trial(s) available for emtricitabine and racivir
| Article | Year |
|---|---|
Hplc-nmr identification of the human urinary metabolites of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analogue active against human immunodeficiency virus (HIV).
Topics: Antiviral Agents; Biotransformation; Chromatography, High Pressure Liquid; Emtricitabine; Glucuronates; HIV; Humans; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Stereoisomerism; Sulfoxides; Zalcitabine | 1996 |
Comparison of three different sensitive assays for hepatitis B virus DNA in monitoring of responses to antiviral therapy.
Topics: Antiviral Agents; DNA, Viral; Emtricitabine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleic Acid Hybridization; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity; Zalcitabine | 2000 |
Comparative pharmacokinetics of Racivir, (+/-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine in rats, rabbits, dogs, monkeys and HIV-infected humans.
Topics: Animals; Antiviral Agents; Dogs; Emtricitabine; Female; HIV Infections; Humans; Macaca mulatta; Male; Pregnancy; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Zalcitabine | 2005 |
Safety, pharmacokinetics, and efficacy of (+/-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine with efavirenz and stavudine in antiretroviral-naïve human immunodeficiency virus-infected patients.
Topics: Administration, Oral; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Emtricitabine; HIV Infections; HIV-1; Humans; Middle Aged; Oxazines; Plasma; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Urine; Zalcitabine | 2005 |
25 other study(ies) available for emtricitabine and racivir
| Article | Year |
|---|---|
Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
Topics: Antiviral Agents; Emtricitabine; HIV; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine; Zidovudine | 1992 |
Substrate specificity of Escherichia coli thymidine phosphorylase for pyrimidine nucleosides with anti-human immunodeficiency virus activity.
Topics: Antiviral Agents; Biological Availability; Deoxyuridine; Dideoxynucleosides; Emtricitabine; Escherichia coli; HIV; Pyrimidine Nucleosides; Stavudine; Substrate Specificity; Thymidine Phosphorylase; Zalcitabine | 1992 |
The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
Topics: Animals; Antiviral Agents; Cell Survival; Cytidine Deaminase; DNA, Viral; Emtricitabine; Growth Inhibitors; Hepatitis B virus; Humans; Macaca fascicularis; Phosphorylation; Stereoisomerism; Substrate Specificity; Zalcitabine | 1992 |
Pharmacokinetics and metabolism of racemic 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rhesus monkeys.
Topics: Administration, Oral; Animals; Antiviral Agents; Body Weight; Emtricitabine; Injections, Intravenous; Macaca mulatta; Male; Stereoisomerism; Tissue Distribution; Zalcitabine | 1992 |
Infectious amplification of wild-type human immunodeficiency virus from patients' lymphocytes and modulation by reverse transcriptase inhibitors in vitro.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cells, Cultured; Dideoxynucleosides; Drug Interactions; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Lymphocyte Activation; Lymphocytes; Models, Biological; Reproducibility of Results; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine; Zidovudine | 1993 |
Evaluation of the potent anti-hepatitis B virus agent (-) cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in a novel in vivo model.
Topics: alpha-Fetoproteins; Animals; Antiviral Agents; Biological Availability; Cell Line; DNA, Viral; Emtricitabine; Hepatitis B; Hepatitis B virus; Humans; Mice; Polymerase Chain Reaction; Virus Replication; Zalcitabine | 1994 |
Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2',3'-didehydro-2',3'-dideoxythymidine in cell culture.
Topics: Base Sequence; Cells, Cultured; Drug Resistance, Microbial; Emtricitabine; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Zalcitabine; Zidovudine | 1994 |
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides.
Topics: Antiviral Agents; Base Sequence; Cell Line; Cloning, Molecular; Dideoxynucleosides; Drug Resistance, Microbial; Emtricitabine; Gene Amplification; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Molecular Sequence Data; Moloney murine leukemia virus; Monocytes; Point Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine | 1993 |
The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase.
Topics: Antiviral Agents; Cytidine Triphosphate; DNA, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Kinetics; Reverse Transcriptase Inhibitors; RNA, Viral; Stereoisomerism; Thiophenes; Zalcitabine | 1993 |
Pharmacokinetics, oral bioavailability, and metabolism in mice and cynomolgus monkeys of (2'R,5'S-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, an agent active against human immunodeficiency virus and human hepatitis B virus.
Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Emtricitabine; Hepatitis B virus; HIV; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Species Specificity; Zalcitabine | 1994 |
Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks.
Topics: Animals; Antigens, Viral; Antiviral Agents; Biopsy; Bromodeoxyuridine; Deoxyguanosine; DNA Replication; DNA, Viral; Ducks; Emtricitabine; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Kinetics; Liver; Time Factors; Virus Replication; Zalcitabine | 1994 |
Intracellular metabolism of (-)- and (+)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in HepG2 derivative 2.2.15 (subclone P5A) cells.
Topics: Antiviral Agents; Cell Line; Dose-Response Relationship, Drug; Emtricitabine; Half-Life; Humans; Liver; Stereoisomerism; Zalcitabine | 1994 |
Pharmacokinetics of 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rats.
Topics: Animals; Antiviral Agents; Dose-Response Relationship, Drug; Emtricitabine; Male; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Zalcitabine | 1994 |
Pharmacokinetics, oral bioavailability, and metabolic disposition in rats of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analog active against human immunodeficiency virus and hepatitis B virus.
Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Biotransformation; Brain; Chromatography, High Pressure Liquid; Emtricitabine; Half-Life; Hepatitis B virus; HIV-1; Humans; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Tissue Distribution; Zalcitabine | 1993 |
High-capacity in vitro assessment of anti-hepatitis B virus compound selectivity by a virion-specific polymerase chain reaction assay.
Topics: Antibody Specificity; Antiviral Agents; Base Sequence; Carcinoma, Hepatocellular; Cell Line; Emtricitabine; Growth Inhibitors; Hepatitis B virus; Humans; Liver Neoplasms; Molecular Sequence Data; Polymerase Chain Reaction; Virion; Zalcitabine | 1993 |
DNA polymerase activity of hepatitis B virus particles: differential inhibition by L-enantiomers of nucleotide analogs.
Topics: Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA-Directed DNA Polymerase; DNA, Viral; Emtricitabine; Hepatitis B virus; Humans; Isotope Labeling; Nucleic Acid Synthesis Inhibitors; Nucleotides; Templates, Genetic; Thymine Nucleotides; Zalcitabine | 1996 |
(-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine (524W91) inhibits hepatitis B virus replication in primary human hepatocytes.
Topics: Antiviral Agents; Blotting, Southern; Cells, Cultured; Emtricitabine; Hepatitis B virus; Humans; Liver; Time Factors; Virus Replication; Zalcitabine | 1996 |
A novel Met-to-Thr mutation in the YMDD motif of reverse transcriptase from feline immunodeficiency virus confers resistance to oxathiolane nucleosides.
Topics: Animals; Antiviral Agents; Binding Sites; Cats; Cell Line; Drug Resistance, Microbial; Emtricitabine; Immunodeficiency Virus, Feline; Lamivudine; Methionine; Mutagenesis, Site-Directed; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Threonine; Viral Plaque Assay; Zalcitabine | 1997 |
In vivo antiviral activity and pharmacokinetics of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in woodchuck hepatitis virus-infected woodchucks.
Topics: Animals; Antiviral Agents; DNA, Viral; Emtricitabine; Half-Life; Hepatitis B; Hepatitis B Virus, Woodchuck; Liver; Marmota; Stereoisomerism; Zalcitabine | 1997 |
Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus.
Topics: Animals; Antiviral Agents; Cells, Cultured; DNA, Circular; DNA, Viral; Emtricitabine; Hepatitis B Virus, Woodchuck; Lamivudine; Liver; Marmota; Rats; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine | 1997 |
Mechanistic studies show that (-)-FTC-TP is a better inhibitor of HIV-1 reverse transcriptase than 3TC-TP.
Topics: Base Sequence; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Lamivudine; Molecular Sequence Data; Oligodeoxyribonucleotides; Reverse Transcriptase Inhibitors; Substrate Specificity; Virus Replication; Zalcitabine | 1999 |
SIV-specific T lymphocyte responses in PBMC and lymphoid tissues of SIV-infected pigtailed macaques during suppressive combination antiretroviral therapy.
Topics: Adenine; Animals; Anti-Retroviral Agents; Drug Therapy, Combination; Emtricitabine; Immunity, Cellular; Interferon-gamma; Linear Models; Macaca nemestrina; Organophosphonates; Primate Diseases; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; T-Lymphocytes; Tenofovir; Viremia; Zalcitabine | 2005 |
Simian immunodeficiency virus infection induces severe loss of intestinal central memory T cells which impairs CD4+ T-cell restoration during antiretroviral therapy.
Topics: Adenine; Animals; Anti-Retroviral Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, Animal; DNA, Viral; Emtricitabine; Flow Cytometry; Immunologic Memory; Lymphoid Tissue; Macaca mulatta; Organophosphonates; Polymerase Chain Reaction; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; T-Lymphocyte Subsets; Tenofovir; Viral Load; Virus Replication; Zalcitabine | 2007 |
Transgenic cardiac-targeted overexpression of human thymidylate kinase.
Topics: Animals; Anti-HIV Agents; DNA Replication; DNA, Mitochondrial; Echocardiography; Emtricitabine; Female; Humans; Hypertrophy, Left Ventricular; Male; Mice; Mice, Transgenic; Mitochondria, Heart; Myocardium; Nucleoside-Phosphate Kinase; Nucleosides; Phosphorylation; Ventricular Function, Left; Zalcitabine; Zidovudine | 2010 |
In vivo blockade of the programmed cell death-1 pathway using soluble recombinant PD-1-Fc enhances CD4+ and CD8+ T cell responses but has limited clinical benefit.
Topics: Adenine; Animals; Anti-Retroviral Agents; Antibodies, Monoclonal; Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Drug Evaluation, Preclinical; Emtricitabine; Histocompatibility Antigens Class I; Immunity, Cellular; Immunoglobulin Fc Fragments; Immunotherapy; Lymphokines; Macaca mulatta; Organophosphonates; Programmed Cell Death 1 Receptor; Recombinant Proteins; RNA, Viral; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Solubility; Tenofovir; Viremia; Zalcitabine | 2013 |