emodin and rhein

emodin has been researched along with rhein in 108 studies

Research

Studies (108)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (1.85)	18.7374
1990's	7 (6.48)	18.2507
2000's	34 (31.48)	29.6817
2010's	48 (44.44)	24.3611
2020's	17 (15.74)	2.80

Authors

Authors	Studies
Kam, CM; Powers, JC; Zalkow, LH; Zembower, DE	1
Duck, CC; Grech, JN; Li, Q; Roufogalis, BD	1
Matsuda, H; Morikawa, T; Shimoda, H; Yoshikawa, M	1
Shang, X; Yuan, Z	1
Diao, C; Hu, D; Jin, L; Song, B; Xu, G; Yang, S; Zhou, X; Zou, Z	1
Coenye, T; Honraet, K; Nadal Jimenez, P; Nelis, HJ; Rigole, P	1
Cui, XR; Gao, L; Komada, F; Koyanagi, J; Saito, S; Shimamura, T; Suzuki, N; Tsukada, M	1
Arioka, S; Hinou, H; Nishimura, S; Sakagami, M; Takemoto, H; Togame, H; Uematsu, R; Yamaguchi, H	1
Fischer, TC; Gosch, C; Gselmann, M; Mirbeth, B; Stich, K; Thallmair, V	1
Cheng, YX; Luo, J; Wang, PC; Wei, W; Yan, YM; Yang, Y; Yang, YX; Zhang, LS; Zhou, XJ	1
Deng, L; Guo, L; Huang, P; Jiang, M; Li, C; Qi, J; Qi, X; Qian, N; Wang, F; Xu, X; Yan, Y; Yang, C; Zhou, H	1
Adepally, U; Banothu, V; Chakrabarti, S; Kumar, K; Luthra, T; M, S; Maddi, SR; Sen, S	1
Inui, K; Kanamitsu, K; Katayama, W; Kitakami, R; Mizuguchi, M; Nakagawa, S; Nakagawa, Y; Okada, T; Sawai, Y; Toyooka, N; Yokoyama, T	1
Johansen, T; Sandnes, D; Teien, G; Ulsaker, G	1
Chen, QH; Zhou, XM	1
Chen, CL; Chen, QH	1
Grimminger, W; Witthohn, K	1
Livesey, JF; Perkins, SL	1
Kuwano, S; Yagi, T; Yamauchi, K	1
Song, X; Wang, D; Yang, G	1
Cheng, KD; Wang, L; Yu, RM; Zhang, H	1
He, J; Jiang, C	1
Correia, H; Fonseca, G; Fraile, G; Marcano, E; Marín, M; Sánchez, Y; Vargas, F; Velásquez, M	1
Lian, Y; Liu, L; Lu, X; Su, Z; Wai, J; Zeng, Y; Zhou, H	1
Chen, LG; Huang, YJ; Lee, LT; Wang, CC; Yang, LL	1
Shang, XY; Yuan, ZB	1
Cheng, FL; Yu, LW; Zeng, YE	1
Bi, ZM; Wang, ZT; Xu, GJ; Xu, LS	1
Gu, L; Wan, M; Wan, Y	1
Chen, XG; Jia, W; Zheng, WJ	1
Chen, JJ; Cheng, YY; Wu, YJ	1
Huang, LQ; Li, XD	1
Guo, SR; Guo, YJ; Ma, XM; Wang, LS	1
Bi, S; Kan, Y; Song, D; Tian, Y; Xu, D; Zhang, H; Zhou, X	1
Li, LX; Li, M; Liu, Y; Sun, P	1
Kobayashi, N; Koyama, J; Morita, I	1
Chou, GX; Lu, YH; Wei, DZ; Zhang, YZ; Zhu, EY	1
Chen, L; Duan, D; Luo, H; Xu, X; Zhuang, Y	1
Leung, KS; Leung, SY; Lu, G; Qian, G	1
Cao, H; Jiao, G; Lv, H; Sun, H; Sun, W; Wang, X; Zhang, G; Zhao, L; Zhou, D	1
Dong, H; Liu, Y; Song, R; Tian, Y; Xu, F; Zhang, Z	1
Deng, KW; He, FY; Liu, PA; Liu, WL; Zhou, HH	1
Bae, JJ; Bak, JP; Choung, ES; Kang, SC; Kwak, JH; Lee, CM; Yoo, HS; Zee, OP	1
Dai, RW; Deng, KW; Fu, J; He, FY; Luo, JY; Pi, FJ; Wu, DZ; Zhou, HH	1
Bian, BL; Fan, MX; Li, PY; Li, XM; Wang, HJ	1
Duan, W; Jiang, Z; Liu, C; Liu, J; Sun, L; Wang, C; Wu, X; Yan, M; Yao, J; Zhang, L	1
Panichayupakaranant, P; Sakunpak, A; Sakunphueak, A	1
Cao, H; Chen, Y; Cheng, J; Fu, J; Li, B; Li, J; Liu, X; Lu, Y; Wu, C; Zheng, J; Zheng, X; Zhou, H	1
Bi, KS; Chen, XH; Gao, X; Jiang, B	1
Ding, L; Liu, Q; Pan, D; Tang, F; Yao, S; Zhang, Q; Zhu, L	1
Chen, YY; Chiang, SY; Chung, JG; Lai, TY; Liao, CL; Lin, JG; Ma, YS; Weng, SW	1
Chen, YY; Chiang, SY; Chung, JG; Lai, TY; Liao, CL; Lin, JG; Ma, YS; Tang, NY; Yang, JS	1
Dong, H; Liu, Y; Song, R; Xu, F; Zhang, Z	1
Gong, H; Huang, X; Tang, W; Wang, H; Xia, Q	1
Li, YX; Liu, Y; Suo, XB; Wu, YH	1
Fang, F; Jin, C; Kong, WJ; Wang, HJ; Wang, JB; Xiao, XH; Zhao, HP; Zhao, YL	2
Cheng, KM; Deng, X; Li, W; Liang, J; Xia, X; Yang, GL; Zhao, LC	1
Ding, X; Li, H; Lu, Y; Qian, L; Yang, Z; Yin, B; Zeng, Z; Zhou, S	1
Gao, B; Shi, Y; Sun, A; Sun, C	1
Gao, JW; Huang, P; Lu, YS; Shi, Z; Yao, MC; Yuan, YM; Zou, JL	1
Feng, W; Ji, L; Li, D; Wang, Y; Wang, Z; Yang, F; Zhang, Q	1
Bai, X; Chen, X; Tian, J	1
Chen, GY; Gong, HL; Huang, X; Tang, WF; Wang, J	1
Chen, GY; Chen, WW; Tang, WF; Wan, MH; Xiang, J; Yu, Q; Zhao, XL	1
Feng, SX; Li, JS; Qu, LB; Shi, YM; Zhao, D	1
Ishizu, T; Okamura, N; Takayama, K; Tsutsumi, H	1
Abdelkawy, M; Abdelwahab, NS; Ali, NW; Emam, AA	1
Jackson, TC; Kochanek, PM; Verrier, JD	1
Cai, B; Cai, H; Chen, J; Guo, H; Li, H; Liu, X; Wu, L; Zhang, K; Zhang, Y	1
Bai, G; Gao, J; Jiang, M; Li, HY; Wang, Q; Zhang, NN	1
Badria, FA; Ibrahim, AS	1
Asres, K; Bisrat, D; Terefe, G; Tewabe, Y	1
He, Y; Li, D; Liu, S; Shen, Y; Yang, J	1
Hu, CJ; Jia, TZ; Xiao, HB; Zhang, XZ; Zhao, N	1
Li, HL; Shi, YB; Wang, H; Wang, HQ; Yang, YB; Zhang, CA; Zhang, XY; Zhang, ZY; Zhu, ZJ	1
Sun, YS; Wang, JH; Yang, SF	1
Gong, XH; Li, Y; Li, YX; Peng, C; Yuan, A; Zeng, DW; Zhang, RQ; Zhao, MJ	1
Chen, GY; Chen, WW; Li, J; Liu, YL; Tang, WF; Wan, MH; Zhao, XL	1
Dong, LC; Dong, X; Fan, YX; Li, HJ; Li, P; Ma, J; Yu, Q	1
Ho, CT; Hung, CM; Kao, JY; Lin, YC; Ma, JW; Way, TD	1
Bian, YQ; Cao, HY; Dong, S; Li, JY; Liu, P; Sun, L; Sun, MY; Sun, RF; Wu, C	1
Li, J; Li, JY; Ren, HY; Su, H; Tang, WF; Wu, FS; Zhang, YM; Zhao, XL	1
Cai, Y; Fu, YJ; Jiang, SS; Jiang, XY; Peng, M; Peng, XQ; Shi, MQ; Wu, Y; Xu, Y; Yang, SY	1
Liu, ZJ; Tan, P; Wang, J; Wang, JB; Xiao, XH; Zhang, HZ	1
Liu, QH; Sun, YW; Tong, XL; Wang, F; Wen, J; Zhang, X	1
Deng, C; Liu, JJ; Wang, HY; Wang, J; Yan, YG; Yin, LM	1
Baek, J; Brailsford, AD; Buddeberg, BS; Cho, BK; Cho, MJ; Choi, DH; Choi, K; Choi, YH; Cowan, DA; Gordon, IL; Hamblin, MR; Jang, JH; Kaelin Agten, A; Khalil, A; Kim, HJ; Kim, JH; Kim, KH; Kim, SI; Kim, SK; Kim, SW; Ko, JS; Koga, S; Lavery, LA; Lee, JH; Lee, JY; Li, H; Li, K; Liu, C; Liu, Q; Luo, X; Ma, MH; Majidin, WNM; Nong, F; O'Driscoll, JM; Osawa, M; Park, GE; Park, J; Park, SH; Pei, M; Phi, JH; Sakaue, H; Sengoku, Y; Sharma, R; Son, Y; Takagi, H; Thein, MS; Thilaganathan, B; Wakabayashi, H; Walker, C; Washington, K; Wason, J; Wen, B; Wojek, N; Yang, H; Zhao, Z; Zhou, L	1
He, Z; Liu, K; Liu, L; Lu, Y; Wu, X; Xu, B; Xu, H; Zhang, T	1
Fan, S; Quan, C; Xiong, W; Zhang, L; Zhang, X	1
Feng, SX; Li, JS; Li, RR; Liu, XF; Qu, LB; Shu, SN; Wang, PY; Zhang, N	1
Fan, Y; Niu, Z; Xu, C; Yang, L; Yang, T	1
Han, L; Wang, L; Wang, Q; Xiao, S; Yang, J; Zhang, T; Zhu, A	1
Aliyu, AB; Ibrahim, MA; Isah, MB; Mohammed, A; Tajuddeen, N	1
Chu, SH; Hu, GZ; Sun, DQ; Yang, R; Zeng, HJ; Zhang, JJ	1
Liu, Y; Mapa, MST; Sprando, RL	1
Hu, Y; Huang, W; Luo, Y; Meng, X; Wang, P; Wu, J; Xiang, L; Xu, C; Zeng, Y; Zhang, Y	1
Aljuffali, IA; Chen, WJ; Fang, JY; Hsu, CY; Huang, TH	1
Alalaiwe, A; Chuang, SY; Fang, JY; Huang, TH; Lin, CF; Nguyen, TMH; Wang, PW	1
Chen, KX; Dong, LL; DU, HL; Gao, F; Lin, MS; Zhong, HY	1
Chen, XJ; Duan, J; Feng, Y; Guo, Y; Li, B; Li, H; Li, M; Li, S; Liu, H; Liu, K; Liu, M; Shi, R; Wang, D; Wang, X; Zhao, L	1
Chen, Q; Fang, B; Feng, L; Huo, X; Lv, X; Ma, X; Mei, Q; Sun, C; Tian, X; Wang, C; Wang, Y; Wu, F; Zhang, Y	1
Ahn, SH; Nguyen, LTH; Shin, HM; Yang, IJ	1
Wang, L; Yang, Y; Zhao, S; Zhou, G	1
Chen, W; Li, S; Ma, Y; Wu, X; Zhang, H	1
Cheng, S; Huang, L; Li, M; Li, S; Shi, J; Wang, H; Yan, H; Zou, C	1
Cao, L; Gao, X; Hu, Y; Li, X; Liu, W; Lv, K; Mei, Y; Tong, X; Wang, J; Wang, Z; Xiao, W	1
Chen, W; Li, S; Ma, Y	1

Reviews

3 review(s) available for emodin and rhein

Article	Year
[Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:8 Topics: Animals; Anthraquinones; Cytokines; Diabetic Nephropathies; Drugs, Chinese Herbal; Emodin; Humans; Interleukin-6; Plants, Medicinal; Rheum; Superoxide Dismutase; Thromboxane B2; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2003
Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases. World journal of gastroenterology, 2017, Feb-21, Volume: 23, Issue:7 Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Antiviral Agents; Artemisia; Ascites; Chlorogenic Acid; Clinical Trials as Topic; Coumarins; Drugs, Chinese Herbal; Emodin; Fatty Liver; Gardenia; Humans; Iridoids; Liver Diseases; Plant Extracts; Rheum	2017
Antidiabetic potential of anthraquinones: A review. Phytotherapy research : PTR, 2020, Volume: 34, Issue:3 Topics: Animals; Anthraquinones; Blood Glucose; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Emodin; Humans; Hypoglycemic Agents; Protein Tyrosine Phosphatase, Non-Receptor Type 1	2020

Other Studies

105 other study(ies) available for emodin and rhein

Article	Year
Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G. Journal of medicinal chemistry, 1992, May-01, Volume: 35, Issue:9 Topics: Anthraquinones; Cathepsin G; Cathepsins; Humans; Leukocyte Elastase; Pancreatic Elastase; Serine Endopeptidases; Structure-Activity Relationship	1992
Novel Ca(2+)-ATPase inhibitors from the dried root tubers of Polygonum Multiflorum. Journal of natural products, 1994, Volume: 57, Issue:12 Topics: Australia; Benzofurans; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Erythrocytes; Glucosides; Humans; In Vitro Techniques; Plant Roots; Plants, Medicinal; Stilbenes	1994
Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity. Bioorganic & medicinal chemistry letters, 2001, Jul-23, Volume: 11, Issue:14 Topics: Anthraquinones; Cell Division; Cells, Cultured; Emodin; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Non-Steroidal; Genistein; Humans; Isoflavones; Phytoestrogens; Plant Preparations; Polygonaceae; Protein Binding; Receptors, Estrogen; Structure-Activity Relationship	2001
Determination of active components in rhubarb and study of their hydrophobicity by micellar electrokinetic chromatography. Bioorganic & medicinal chemistry letters, 2003, Feb-24, Volume: 13, Issue:4 Topics: Anthraquinones; Calibration; Chromatography, Micellar Electrokinetic Capillary; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Plant Extracts; Rheum; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Styrenes; Thermodynamics	2003
Isolation and inhibitory activity against ERK phosphorylation of hydroxyanthraquinones from rhubarb. Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3 Topics: Animals; Anthraquinones; Antifungal Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chromatography, Gel; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Mice; Microwaves; NIH 3T3 Cells; Phosphorylation; Plant Extracts; Rheum; Spectrum Analysis	2006
In vitro inhibition of Streptococcus mutans biofilm formation on hydroxyapatite by subinhibitory concentrations of anthraquinones. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anthraquinones; Anti-Bacterial Agents; Biofilms; Durapatite; Microbial Sensitivity Tests; Streptococcus mutans	2007
Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones. European journal of medicinal chemistry, 2008, Volume: 43, Issue:6 Topics: Anthraquinones; Antineoplastic Agents, Phytogenic; Boraginaceae; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Lithospermum; Magnetic Resonance Spectroscopy; Naphthoquinones; Rheum; Spectrometry, Mass, Electrospray Ionization	2008
Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase. Bioorganic & medicinal chemistry, 2010, Feb-15, Volume: 18, Issue:4 Topics: Base Sequence; DNA Primers; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glycoproteins; Neuraminidase; Recombinant Proteins; Structure-Activity Relationship; Trypanosoma cruzi	2010
Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora. Journal of agricultural and food chemistry, 2012, Dec-12, Volume: 60, Issue:49 Topics: Agrochemicals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Drug Stability; Erwinia amylovora; Flowers; Germination; Hydrogen-Ion Concentration; Malus; Microbial Sensitivity Tests; Naphthoquinones; Plant Diseases; Quinones; Toxicity Tests	2012
Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy. Bioorganic & medicinal chemistry letters, 2013, Jul-01, Volume: 23, Issue:13 Topics: Anthraquinones; Aspergillus fumigatus; Cell Survival; Diabetic Nephropathies; Dose-Response Relationship, Drug; Extracellular Matrix; Glycosides; Humans; Interleukin-6; Mesangial Cells; Molecular Structure; Naphthalenes; Renal Insufficiency, Chronic; Rumex; Structure-Activity Relationship	2013
Synthesis and biological evaluation of rhein amides as inhibitors of osteoclast differentiation and bone resorption. European journal of medicinal chemistry, 2016, Nov-10, Volume: 123 Topics: 3T3-L1 Cells; Amides; Animals; Anthraquinones; Biomarkers; Bone Marrow Cells; Bone Resorption; Cell Differentiation; Chemistry Techniques, Synthetic; Macrophages; Male; Mice; NFATC Transcription Factors; Osteoclasts; RANK Ligand	2016
Discovery of novel pyrido-pyrrolidine hybrid compounds as alpha-glucosidase inhibitors and alternative agent for control of type 1 diabetes. European journal of medicinal chemistry, 2020, Feb-15, Volume: 188 Topics: alpha-Glucosidases; Animals; Binding Sites; Blood Proteins; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Discovery; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Male; Mice; Molecular Docking Simulation; Molecular Structure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Solubility; Streptozocin; Structure-Activity Relationship; Thermodynamics	2020
Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis. Bioorganic & medicinal chemistry, 2021, 08-15, Volume: 44 Topics: Amyloid Neuropathies, Familial; Anthraquinones; Crystallography, X-Ray; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Xanthones	2021
Mutagenicity of crude senna and senna glycosides in Salmonella typhimurium. Pharmacology & toxicology, 1992, Volume: 71, Issue:3 Pt 1 Topics: Animals; Anthraquinones; Biotransformation; Chromatography, High Pressure Liquid; Emodin; Flavonoids; Glycoside Hydrolases; Kaempferols; Microsomes, Liver; Mutagens; Quercetin; Rats; Salmonella typhimurium; Senna Extract	1992
[Biochemical study of Chinese rhubarb. XXII. Inhibitory effect of anthraquinone derivatives on Na+-K+-ATPase of the rabbit renal medulla and their diuretic action]. Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:1 Topics: Animals; Anthraquinones; Diuresis; Emodin; Kidney Medulla; Male; Plants, Medicinal; Rabbits; Rheum; Sodium-Potassium-Exchanging ATPase	1988
[Biochemical study of Chinese rhubarb. XIX. Localization of inhibition of anthraquinone derivatives on the mitochondrial respiratory chain]. Yao xue xue bao = Acta pharmaceutica Sinica, 1987, Volume: 22, Issue:1 Topics: Animals; Anthraquinones; Electron Transport Complex III; Electron Transport Complex IV; Emodin; Mitochondria, Liver; NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Plants, Medicinal; Rats; Rheum; Succinate Dehydrogenase	1987
Analytics of senna drugs with regard to the toxicological discussion of anthranoids. Pharmacology, 1993, Volume: 47 Suppl 1 Topics: Anthraquinones; Cathartics; Chromatography, High Pressure Liquid; Emodin; Prodrugs; Risk Factors; Senna Extract; Sennosides	1993
A rapid high-performance thin-layer chromatographic urine screen for laxative abuse. Clinical biochemistry, 1993, Volume: 26, Issue:3 Topics: Anthraquinones; Bisacodyl; Cathartics; Chromatography, High Pressure Liquid; Emodin; Female; Humans; Male; Middle Aged; Phenolphthalein; Phenolphthaleins; Substance-Related Disorders	1993
The synergistic purgative action of aloe-emodin anthrone and rhein anthrone in mice: synergism in large intestinal propulsion and water secretion. The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:1 Topics: Animals; Anthraquinones; Body Water; Cathartics; Drug Synergism; Emodin; Female; Intestine, Large; Mice; Mice, Inbred ICR; Senna Extract	1997
Determination of pKa values of anthraquinone compounds by capillary electrophoresis. Electrophoresis, 2001, Volume: 22, Issue:3 Topics: Anthraquinones; Electrophoresis, Capillary; Emodin; Molecular Structure	2001
[Hairy-root culture of Polygonium multiflorum Thunb. and the production of its active constituents-anthraquinones]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2002, Volume: 18, Issue:1 Topics: Anthraquinones; Emodin; Organ Culture Techniques; Plant Roots; Polygonaceae; Rhizobium; Transformation, Genetic	2002
Simultaneous determination of Aloe-emodin and Rhein by synchronous fluorescence spectroscopy. Journal of pharmaceutical and biomedical analysis, 2002, Jul-20, Volume: 29, Issue:4 Topics: Anthraquinones; Drug Combinations; Emodin; Hydrogen-Ion Concentration; Indicators and Reagents; Spectrometry, Fluorescence	2002
Studies on the photostability and phototoxicity of aloe-emodin, emodin and rhein. Die Pharmazie, 2002, Volume: 57, Issue:6 Topics: Acetylcholinesterase; Aloe; Anthraquinones; Dermatitis, Phototoxic; Drug Stability; Emodin; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Linoleic Acid; Lipid Peroxidation; Photochemistry; Reactive Oxygen Species; Ultraviolet Rays	2002
[Preliminary study on chemical changes in the decocting process of radix et rhizoma Rhei]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1999, Volume: 24, Issue:5 Topics: Anthraquinones; Drugs, Chinese Herbal; Emodin; Hot Temperature; Mixed Function Oxygenases; Plant Roots; Plants, Medicinal; Rheum; Rhizome	1999
Inducible nitric oxide synthase inhibitors of Chinese herbs III. Rheum palmatum. Planta medica, 2002, Volume: 68, Issue:10 Topics: Animals; Anthraquinones; Blotting, Western; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Drugs, Chinese Herbal; Emodin; Humans; Inhibitory Concentration 50; Isoenzymes; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Mixed Function Oxygenases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phytotherapy; Plant Roots; Prostaglandin-Endoperoxide Synthases; Rheum	2002
[Determination of six effective components in Rheum by cyclodextrin modified micellar electrokinetic chromatography]. Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:10 Topics: Anthraquinones; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Emodin; Plants, Medicinal; Quality Control; Rheum; Stilbenes	2002
[Study on the quantitative change of anthraquinonoids of Rhei in the preparation of dachengqi]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2002, Volume: 27, Issue:1 Topics: Anthraquinones; Citrus; Drug Combinations; Drugs, Chinese Herbal; Emodin; Hot Temperature; Magnolia; Materia Medica; Plant Extracts; Plants, Medicinal; Rheum; Sulfates; Time Factors	2002
[Studies on the chemical constituents of Dendrobium fimbriatum]. Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:7 Topics: Anthraquinones; Antineoplastic Agents, Phytogenic; Cell Division; Dendrobium; Emodin; Heterocyclic Compounds, 4 or More Rings; Humans; Lactones; Molecular Structure; Plants, Medicinal; Stomach Neoplasms; Tumor Cells, Cultured	2003
[Determination of active anthraquinones in Rheum and its tea preparations by micellar electrokinetic capillary electrophoresis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:9 Topics: Anthraquinones; Chromatography, Micellar Electrokinetic Capillary; Emodin; Plant Preparations; Plants, Medicinal; Rheum	2004
[Simultaneous determination of 4 anthraquinones in Kuhuang injection by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:11 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Emodin; Injections; Plants, Medicinal; Rheum; Sophora	2004
[Influence of processing rhubarb on it's anthraquinone contents]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:12 Topics: Anthraquinones; Drugs, Chinese Herbal; Emodin; Hot Temperature; Plant Roots; Plants, Medicinal; Quality Control; Reproducibility of Results; Rheum; Technology, Pharmaceutical	2005
[A new isoflavone from Huoxue Yiqi Tang]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:15 Topics: Anthraquinones; Drug Combinations; Drugs, Chinese Herbal; Emodin; Isoflavones; Plants, Medicinal	2005
Spectroscopic characterization of effective components anthraquinones in Chinese medicinal herbs binding with serum albumins. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 62, Issue:1-3 Topics: Anthraquinones; Binding Sites; Drugs, Chinese Herbal; Emodin; Humans; Models, Molecular; Molecular Structure; Serum Albumin; Serum Albumin, Bovine	2005
[Study on the selection of crude drugs of rhubarb dispensing granule]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:4 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Plant Roots; Plants, Medicinal; Quality Control; Rheum; Technology, Pharmaceutical	2006
Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis. Journal of chromatography. A, 2007, Mar-23, Volume: 1145, Issue:1-2 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Emodin; Glucosides; Molecular Structure; Reproducibility of Results; Rheum; Senna Extract; Sennosides	2007
Preparative isolation and purification of hydroxyanthraquinones from Rheum tanguticum Maxim. on normal phase silica gel: using a Flash Master Personal system. Preparative biochemistry & biotechnology, 2007, Volume: 37, Issue:3 Topics: Anthraquinones; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Emodin; Glucosides; Medicine, Chinese Traditional; Molecular Structure; Plant Extracts; Plants, Medicinal; Rheum; Silica Gel; Silicon Dioxide; Spectrophotometry, Ultraviolet	2007
In situ synthesis of molecularly imprinted polymers on glass microspheres in a column. Analytical and bioanalytical chemistry, 2007, Volume: 389, Issue:4 Topics: Acrylamide; Anthraquinones; Chromatography, Liquid; Emodin; Glass; Methacrylates; Microscopy, Electron, Scanning; Microspheres; Molecular Imprinting; Molecular Structure; Nitriles; Polymers; Pressure; Rheology; Solid Phase Extraction	2007
Optimization and validation of a chromatographic method for the simultaneous quantification of six bioactive compounds in Rhizoma et Radix Polygoni Cuspidati. The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:1 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Molecular Structure; Reproducibility of Results; Resveratrol; Rhizome; Stilbenes; Technology, Pharmaceutical	2008
Simultaneous determination by UPLC-ESI-MS of scoparone, capillarisin, rhein, and emodin in rat urine after oral administration of Yin Chen Hao Tang preparation. Journal of separation science, 2008, Volume: 31, Issue:4 Topics: Administration, Oral; Animals; Anthraquinones; Chromatography, Liquid; Chromones; Coumarins; Drugs, Chinese Herbal; Emodin; Male; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization	2008
Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction. Journal of pharmaceutical and biomedical analysis, 2008, Jul-15, Volume: 47, Issue:3 Topics: Administration, Oral; Animals; Anthraquinones; Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Female; Lignans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry	2008
[A new qualitative and quantitative analytical method of chromatographic fingerprints: total quantum statistical moment]. Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:2 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ecosystem; Emodin; Plant Roots; Plants, Medicinal; Quantum Theory; Rheum	2008
Anti-proliferative effects of estrogen receptor-modulating compounds isolated from Rheum palmatum. Archives of pharmacal research, 2008, Volume: 31, Issue:6 Topics: Anthraquinones; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Emodin; Estrogen Receptor Modulators; Humans; Inhibitory Concentration 50; Plant Roots; Receptors, Estrogen; Recombinant Proteins; Rheum	2008
[Theoretical and experimental studies on solubility parameters of multiple components for traditional Chinese materia medica with HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:6 Topics: Anthraquinones; Caffeine; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Materia Medica; Models, Chemical; Regression Analysis; Solubility; Temperature	2008
[Studies on chemical constituents and volatile oil of Xiaochengqi decoction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:9 Topics: Anthraquinones; Biphenyl Compounds; Cinnamates; Cyclohexenes; Cymenes; Drugs, Chinese Herbal; Emodin; Gallic Acid; Gas Chromatography-Mass Spectrometry; Lignans; Limonene; Monoterpenes; Oils, Volatile; Sitosterols; Terpenes	2008
Participation of cathepsin B in emodin-induced apoptosis in HK-2 Cells. Toxicology letters, 2008, Oct-01, Volume: 181, Issue:3 Topics: Anthraquinones; Apoptosis; Blotting, Western; Caspase 3; Cathepsin B; Cell Line; Cell Survival; Emodin; Enzyme Inhibitors; Epithelial Cells; Humans; Kidney Tubules, Proximal; Reverse Transcriptase Polymerase Chain Reaction	2008
Quantitative HPLC determination and extraction of anthraquinones in Senna alata leaves. Journal of chromatographic science, 2009, Volume: 47, Issue:3 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Emodin; Plant Leaves; Reproducibility of Results; Senna Plant; Sensitivity and Specificity	2009
Targeting CpG DNA to screen and isolate anti-sepsis fraction and monomers from traditional Chinese herbs using affinity biosensor technology. International immunopharmacology, 2009, Volume: 9, Issue:9 Topics: Aconitum; Animals; Anthraquinones; Biosensing Techniques; Cell Line; Chemical Fractionation; Chromatography, High Pressure Liquid; CpG Islands; DNA, Bacterial; Drug Evaluation, Preclinical; Drug Synergism; Drugs, Chinese Herbal; Emodin; Enzyme Inhibitors; Escherichia coli; Escherichia coli Infections; Female; Gene Expression Regulation; Immunity, Innate; Lipid A; Macrophages; Mice; Mice, Inbred Strains; Phytotherapy; Protein Binding; Sepsis; Toll-Like Receptor 9; Tumor Necrosis Factor-alpha	2009
[Simultaneous determination of anthraquinones in Liuwei'anxiao capsules by HPLC]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2009, Volume: 32, Issue:6 Topics: Anthraquinones; Capsules; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Emodin; Plants, Medicinal; Quality Control; Reproducibility of Results	2009
Mixed hemimicelles SPE based on CTAB-coated Fe3O4/SiO2 NPs for the determination of herbal bioactive constituents from biological samples. Talanta, 2010, Mar-15, Volume: 80, Issue:5 Topics: Anthraquinones; Cetrimonium; Cetrimonium Compounds; Emodin; Humans; Limit of Detection; Linear Models; Magnetics; Nanoparticles; Rheum; Silicon Dioxide; Solid Phase Extraction	2010
Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9. International journal of oncology, 2010, Volume: 36, Issue:5 Topics: Aloe; Anthraquinones; Cell Line, Tumor; Cell Movement; Drug Screening Assays, Antitumor; Emodin; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; RNA, Messenger; Tongue Neoplasms; Urokinase-Type Plasminogen Activator	2010
Emodin, aloe-emodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells. Anticancer research, 2010, Volume: 30, Issue:3 Topics: 14-3-3 Proteins; Anthraquinones; Ataxia Telangiectasia Mutated Proteins; Biomarkers, Tumor; BRCA1 Protein; Cell Cycle Proteins; Cell Line, Tumor; Comet Assay; DNA Damage; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; DNA-Activated Protein Kinase; DNA-Binding Proteins; Emodin; Enzyme Inhibitors; Exonucleases; Exoribonucleases; Gene Expression; Humans; Neoplasm Proteins; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Tongue Neoplasms; Tumor Suppressor Proteins	2010
Pharmacokinetic comparison in rats of six bioactive compounds between Da-Cheng-Qi decoction and its parent herbal medicines. Natural product communications, 2010, Volume: 5, Issue:5 Topics: Animals; Anthraquinones; Area Under Curve; Biphenyl Compounds; Chromatography, Liquid; Drugs, Chinese Herbal; Emodin; Female; Flavanones; Hesperidin; Lignans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry	2010
Effects of food and gender on the pharmacokinetics of rhein and emodin in rats after oral dosing with Da-Cheng-Qi decoction. Phytotherapy research : PTR, 2011, Volume: 25, Issue:1 Topics: Animals; Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Eating; Emodin; Female; Half-Life; Male; Rats; Rats, Sprague-Dawley; Sex Factors	2011
[Liposomal encapsulation of free anthraquinones in rhizoma et radix rhei and its quality control]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:4 Topics: Anthraquinones; Calcium; Chromatography, High Pressure Liquid; Drug Carriers; Drug Stability; Drugs, Chinese Herbal; Emodin; Liposomes; Particle Size; Quality Control; Reproducibility of Results; Rheum; Rhizome	2010
[Tissue distribution of free anthraquinones in SD rats after orally administered extracts from raw and prepared rhubarbs]. Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:3 Topics: Administration, Oral; Animals; Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Female; Male; Plant Roots; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Rheum; Tandem Mass Spectrometry; Tissue Distribution	2011
The use of response surface methodology to optimize the ultrasound-assisted extraction of five anthraquinones from Rheum palmatum L. Molecules (Basel, Switzerland), 2011, Jul-15, Volume: 16, Issue:7 Topics: Anthraquinones; Emodin; Rheum; Ultrasonics	2011
Screening for novel quorum-sensing inhibitors to interfere with the formation of Pseudomonas aeruginosa biofilm. Journal of medical microbiology, 2011, Volume: 60, Issue:Pt 12 Topics: Anthraquinones; Anti-Bacterial Agents; Biofilms; Coumarins; Drugs, Chinese Herbal; Emodin; Escherichia coli; Microbial Sensitivity Tests; Naphthoquinones; Pseudomonas aeruginosa; Quorum Sensing; Stenotrophomonas maltophilia	2011
A comparative study on the tissue distributions of rhubarb anthraquinones in normal and CCl4-injured rats orally administered rhubarb extract. Journal of ethnopharmacology, 2011, Oct-11, Volume: 137, Issue:3 Topics: Administration, Oral; Animals; Anthraquinones; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Female; Kidney; Liver; Male; Plant Roots; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rheum; Spleen; Tandem Mass Spectrometry; Tissue Distribution	2011
Development of a liquid chromatography tandem mass spectrometry method for simultaneous determination of eight adulterants in slimming functional foods. Journal of chromatography. A, 2011, Oct-21, Volume: 1218, Issue:42 Topics: Anthraquinones; Chromatography, Liquid; Clopamide; Cyclobutanes; Diet, Reducing; Emodin; Ephedrine; Fenfluramine; Food Contamination; Functional Food; Linear Models; Methanol; Phenylpropanolamine; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Temperature	2011
A novel UPLC-MS/MS method for simultaneous quantification of rhein, emodin, berberine and baicalin in rat plasma and its application in a pharmacokinetic study. Bioanalysis, 2012, Volume: 4, Issue:10 Topics: Animals; Anthraquinones; Berberine; Chromatography, High Pressure Liquid; Colonic Diseases, Functional; Drugs, Chinese Herbal; Emodin; Flavonoids; Medicine, Chinese Traditional; Plasma; Rats; Reproducibility of Results; Sensitivity and Specificity; Statistics, Nonparametric; Tandem Mass Spectrometry	2012
[Determination of four anthraquinones in Sanhuang tablets by QAMS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:2 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Reproducibility of Results; Rheum; Tablets; Technology, Pharmaceutical	2012
[Analysis of emodin and its metabolites based on hollow fiber liquid phase microextraction]. Se pu = Chinese journal of chromatography, 2012, Volume: 30, Issue:5 Topics: Animals; Anthraquinones; Chromatography, High Pressure Liquid; Emodin; Female; Liquid Phase Microextraction; Male; Rats; Rats, Wistar	2012
Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction [See Text] in rats. Chinese journal of integrative medicine, 2012, Volume: 18, Issue:9 Topics: Administration, Oral; Animals; Anthraquinones; Biphenyl Compounds; Drug Incompatibility; Emodin; Flavanones; Hesperidin; Lignans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley	2012
Effect of acute pancreatitis on the pharmacokinetics of Chinese herbal ointment Liu-He-Dan in anaesthetized rats. Journal of ethnopharmacology, 2013, Jan-09, Volume: 145, Issue:1 Topics: Administration, Cutaneous; Amylases; Animals; Anthraquinones; Arginine; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Male; Ointments; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley	2013
Comparative pharmacokinetics of five rhubarb anthraquinones in normal and thrombotic focal cerebral ischemia-induced rats. Phytotherapy research : PTR, 2013, Volume: 27, Issue:10 Topics: Animals; Anthraquinones; Brain Ischemia; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Rheum	2013
The influence of rhein 8-O-β-D-glucopyranoside on the purgative action of sennoside A from rhubarb in mice. Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:12 Topics: Animals; Anthracenes; Anthraquinones; Bacteria; Cathartics; Constipation; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Emodin; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred Strains; Monosaccharides; Phytotherapy; Rheum; Senna Extract; Sennosides	2012
Validated stability indicating TLC-densitometric method for the determination of diacerein. Journal of chromatographic science, 2014, Volume: 52, Issue:1 Topics: Anthraquinones; Chromatography, Thin Layer; Densitometry; Drug Contamination; Drug Stability; Emodin; Reproducibility of Results; Sensitivity and Specificity	2014
Anthraquinone-2-sulfonic acid (AQ2S) is a novel neurotherapeutic agent. Cell death & disease, 2013, Jan-10, Volume: 4 Topics: Animals; Anthraquinones; Apoptosis; Caspases; Cell Survival; Cells, Cultured; Chromones; Emodin; Hydrogen Peroxide; Lipid Peroxidation; Morpholines; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Staurosporine	2013
Comparative pharmacokinetics study of three anthraquinones in rat plasma after oral administration of Radix et Rhei Rhizoma extract and Dahuang Fuzi Tang by high performance liquid chromatography-mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2013, Mar-25, Volume: 76 Topics: Aconitum; Administration, Oral; Animals; Anthraquinones; Asarum; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Male; Mass Spectrometry; Plant Extracts; Rats; Rats, Sprague-Dawley; Rheum; Sensitivity and Specificity; Time Factors	2013
[Active ingredients in rhubarb with anti-proliferative effects on scar fibroblasts]. Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:12 Topics: Anthraquinones; Cell Cycle; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Drugs, Chinese Herbal; Emodin; Fibroblasts; Gallic Acid; Humans; Plant Stems; Plants, Medicinal; Rheum	2012
Evaluation of natural anthracene-derived compounds as antimitotic agents. Drug discoveries & therapeutics, 2013, Volume: 7, Issue:2 Topics: Anthracenes; Anthraquinones; Antimitotic Agents; Antineoplastic Agents; Dose-Response Relationship, Drug; Emodin; Mitosis; Onions; Plant Roots; Time Factors	2013
Antitrypanosomal activity of aloin and its derivatives against Trypanosoma congolense field isolate. BMC veterinary research, 2014, Mar-10, Volume: 10 Topics: Animals; Anthraquinones; Diminazene; Dose-Response Relationship, Drug; Emodin; Female; Mice; Molecular Structure; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African	2014
Molecular spectroscopic studies on the interactions of rhein and emodin with thioglycolic acid-capped core/shell CdTe/CdS quantum dots and their analytical applications. Luminescence : the journal of biological and chemical luminescence, 2015, Volume: 30, Issue:1 Topics: Anthraquinones; Cadmium Compounds; Emodin; Humans; Molecular Structure; Particle Size; Quantum Dots; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sulfides; Surface Properties; Tellurium; Thioglycolates	2015
[Metabolomics analysis revealing multiple compounds changed in rhubarb after processing]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:9 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Emodin; Food Handling; Food Preservation; Metabolomics; Multivariate Analysis; Principal Component Analysis; Rheum; Tandem Mass Spectrometry	2014
Simultaneous determination of five anthraquinones in a Chinese traditional preparation by RP-HPLC using an improved extraction procedure. Journal of integrative medicine, 2014, Volume: 12, Issue:5 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drugs, Chinese Herbal; Emodin	2014
[Optimization of ionic liquid based microwave assisted extraction of five anthraquinones from Polygonum cuspidatum by response surface method]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:5 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Ionic Liquids; Microwaves; Plant Roots; Rhizome; Technology, Pharmaceutical; Temperature	2014
The Influence of Aconitum carmichaelii Debx. on the Pharmacokinetic Characteristics of Main Components in Rheum palmatum L. Phytotherapy research : PTR, 2015, Volume: 29, Issue:8 Topics: Aconitum; Administration, Oral; Animals; Anthraquinones; Drug Interactions; Drugs, Chinese Herbal; Emodin; Male; Plant Extracts; Plant Roots; Rats, Sprague-Dawley; Rheum; Rhizome	2015
Effect of acute pancreatitis on the pharmacokinetics of Chinese herbal micron Liuhe Pill ointment in rats. Chinese journal of integrative medicine, 2015, Volume: 21, Issue:12 Topics: Acute Disease; Animals; Anthraquinones; Drugs, Chinese Herbal; Emodin; Male; Ointments; Pancreatitis; Rats; Rats, Sprague-Dawley	2015
Synergistic effects of rhubarb-gardenia herb pair in cholestatic rats at pharmacodynamic and pharmacokinetic levels. Journal of ethnopharmacology, 2015, Dec-04, Volume: 175 Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Anthraquinones; Aspartate Aminotransferases; Bilirubin; Cholestasis; Drug Synergism; Emodin; Fruit; Gardenia; Iridoids; Liver; Male; Plant Extracts; Protective Agents; Rats, Sprague-Dawley; Rheum; Rhizome	2015
Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells. Oncotarget, 2016, Sep-13, Volume: 7, Issue:37 Topics: Anthraquinones; Breast Neoplasms; Carcinogenesis; Cell Movement; Down-Regulation; Emodin; Female; Glucosides; Humans; Neoplasm Metastasis; Phytotherapy; Plant Roots; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Rheum; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Y-Box-Binding Protein 1	2016
Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis. World journal of gastroenterology, 2017, Feb-28, Volume: 23, Issue:8 Topics: Acute Disease; Alanine Transaminase; Animals; Anthraquinones; Aspartate Aminotransferases; Biphenyl Compounds; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Emodin; Flavanones; Hesperidin; Inflammation; Lignans; Liver; Male; Pancreatitis; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry	2017
[Effects of wine processed Rheum palmatum on tissue distribution of aloe-emodin, rhein and emodin in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:8 Topics: Animals; Anthraquinones; Emodin; Rats; Rats, Sprague-Dawley; Rheum; Tissue Distribution; Wine	2017
[Activating blood biological potency assay and chemical fingerprint chromatogram applied to quality evaluation of rhubarb]. Yao xue xue bao = Acta pharmaceutica Sinica, 2017, Volume: 52, Issue:3 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Quality Control; Rheum	2017
[Comparative Study on Boiling Powder and Traditional Herbal Pieces of Rhubarb]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2016, Volume: 39, Issue:1 Topics: Animals; Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Powders; Rats; Rats, Sprague-Dawley; Rheum	2016
[The Effect in Extraction of Different Ratio of Dahuang-Taoren for Ten Kinds of Chemical Constituents from Rhizoma Rhei]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2016, Volume: 39, Issue:7 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Rheum; Rhizome; Senna Extract; Sennosides	2016
Journal of textile science & engineering, 2018, Volume: 8, Issue:2 Topics: Adult; Anabolic Agents; Androgens; Animals; Anthraquinones; Birth Weight; Body Mass Index; Carbon Isotopes; Cardiac Output; Case-Control Studies; Chromatography, High Pressure Liquid; Doping in Sports; Drugs, Chinese Herbal; Echocardiography; Emodin; Estranes; Exercise; Female; Gas Chromatography-Mass Spectrometry; Glucosides; Glycolysis; Hemodynamics; Hemoglobins; Herb-Drug Interactions; Humans; Hypothermia, Induced; Lactic Acid; Linear Models; Male; Monoterpenes; Muscle, Skeletal; Myoglobin; Nandrolone; Obesity; Oxygen Consumption; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Pregnant Women; Prospective Studies; Pulmonary Gas Exchange; Rats; Rats, Sprague-Dawley; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Steroids; Substance Abuse Detection; Sulfates; Tandem Mass Spectrometry; Testosterone	2018
Characterization of binding interactions of anthraquinones and bovine β-lactoglobulin. Food chemistry, 2019, May-30, Volume: 281 Topics: Animals; Anthraquinones; Cattle; Circular Dichroism; Emodin; Hydrophobic and Hydrophilic Interactions; Lactoglobulins; Models, Theoretical; Molecular Docking Simulation; Polyphenols; Spectroscopy, Fourier Transform Infrared; Whey Proteins	2019
Proteoliposome-based model for screening inhibitors targeting histidine kinase AgrC. Chemical biology & drug design, 2019, Volume: 93, Issue:5 Topics: Anthraquinones; Bacterial Proteins; Biofilms; Emodin; Gene Expression Regulation, Bacterial; Medicine, Chinese Traditional; Microbial Sensitivity Tests; Particle Size; Protein Kinases; Proteolipids; Signal Transduction; Staphylococcus aureus; Virulence Factors	2019
Pharmacodynamics of Five Anthraquinones (Aloe-emodin, Emodin, Rhein, Chysophanol, and Physcion) and Reciprocal Pharmacokinetic Interaction in Rats with Cerebral Ischemia. Molecules (Basel, Switzerland), 2019, May-17, Volume: 24, Issue:10 Topics: Aloe; Animals; Anthraquinones; Brain Ischemia; Disease Models, Animal; Drug Therapy, Combination; Emodin; Male; Plant Extracts; Rats; Rheum	2019
Protic Ionic Liquids as Efficient Solvents in Microwave-Assisted Extraction of Rhein and Emodin from Molecules (Basel, Switzerland), 2019, Jul-30, Volume: 24, Issue:15 Topics: Anthraquinones; Chromatography, High Pressure Liquid; Emodin; Factor Analysis, Statistical; Humans; Imidazoles; Ionic Liquids; Liquid-Liquid Extraction; Mesylates; Microwaves; Plant Extracts; Rheum; Solvents	2019
Anthraquinones in the aqueous extract of Cassiae semen cause liver injury in rats through lipid metabolism disorder. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 64 Topics: Animals; Anthraquinones; Cassia; Cell Line; Cell Survival; Emodin; Female; Humans; Lipid Metabolism; Lipids; Liver; Male; Phytochemicals; Rats; Rats, Sprague-Dawley; Seeds; Senna Extract; Stem Cells	2019
Inhibitory effects of four anthraquinones on tyrosinase activity: Insight from spectroscopic analysis and molecular docking. International journal of biological macromolecules, 2020, Oct-01, Volume: 160 Topics: Anthraquinones; Catalytic Domain; Circular Dichroism; Emodin; Enzyme Inhibitors; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Monophenol Monooxygenase; Spectrometry, Fluorescence	2020
Anthraquinones inhibit cytochromes P450 enzyme activity in silico and in vitro. Journal of applied toxicology : JAT, 2021, Volume: 41, Issue:9 Topics: Animals; Anthraquinones; Computer Simulation; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Emodin; Humans; In Vitro Techniques; Isoenzymes; Microsomes, Liver; Quantitative Structure-Activity Relationship; Recombinant Proteins	2021
Assessment of the anti-inflammatory effects of three rhubarb anthraquinones in LPS-Stimulated RAW264.7 macrophages using a pharmacodynamic model and evaluation of the structure-activity relationships. Journal of ethnopharmacology, 2021, Jun-12, Volume: 273 Topics: Animals; Anthraquinones; Emodin; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; RAW 264.7 Cells; Rheum; Structure-Activity Relationship	2021
Rhubarb hydroxyanthraquinones act as antiobesity agents to inhibit adipogenesis and enhance lipolysis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 146 Topics: 3T3 Cells; Adipocytes; Adipogenesis; Animals; Anthraquinones; Anti-Obesity Agents; Cell Survival; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Emodin; Glycerol; Liver; Mice; Random Allocation; Rats; Rats, Sprague-Dawley; Rheum; Up-Regulation	2022
A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 145 Topics: Administration, Topical; Animals; Anthraquinones; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Emodin; HaCaT Cells; Humans; Imiquimod; Inflammation; Keratinocytes; Macrophages; Mice; Psoriasis; Rheum; Skin Absorption; Swine	2022
[Mechanism of combined treatment of rhein and emodin in Rhubarb for ulcerative colitis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:15 Topics: Animals; Anthraquinones; Colitis, Ulcerative; Colon; Disease Models, Animal; Emodin; Interleukin-6; Mice; Proto-Oncogene Proteins c-akt; Rheum; Tumor Necrosis Factor-alpha	2022
Pharmacokinetic characteristics of emodin in polygoni Multiflori Radix Praeparata. Journal of ethnopharmacology, 2023, Mar-01, Volume: 303 Topics: Animals; Anthraquinones; Chromatography, High Pressure Liquid; Emodin; Glycosides; Polygonum; Rats; Rats, Sprague-Dawley	2023
UGTs-mediated metabolic interactions contribute to enhanced anti-inflammation activity of Jinhongtang. Journal of ethnopharmacology, 2023, Mar-25, Volume: 304 Topics: Animals; Anti-Inflammatory Agents; COVID-19; Emodin; Humans; Lipopolysaccharides; Mice; Rats; Sepsis	2023
Anti-Psoriatic Effect of International journal of molecular sciences, 2022, Dec-15, Volume: 23, Issue:24 Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Emodin; Interleukin-17; Mice; Psoriasis; Rheum	2022
Soluble Protein Content, Bioactive Compounds and the Antioxidant Activity in Seeds of Ten Rheum tanguticum Lines from Qinghai-Tibet Plateau. Chemistry & biodiversity, 2023, Volume: 20, Issue:3 Topics: Anthraquinones; Antioxidants; Emodin; Rheum; Seeds; Tibet	2023
Prediction and verification of the active ingredients and potential targets of Erhuang Quzhi Granules on non-alcoholic fatty liver disease based on network pharmacology. Journal of ethnopharmacology, 2023, Jul-15, Volume: 311 Topics: Animals; Drugs, Chinese Herbal; Emodin; Lipids; Mice; Molecular Docking Simulation; Network Pharmacology; NF-kappa B; Non-alcoholic Fatty Liver Disease; Tumor Necrosis Factor-alpha	2023
[Spectrum-effect relationship of total anthraquinone extract of Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023, May-20, Volume: 43, Issue:5 Topics: Animals; Anthraquinones; Antioxidants; Cassia; Chemical and Drug Induced Liver Injury, Chronic; Emodin; Fluorouracil; Mice; Plant Extracts	2023
Comparative pharmacokinetics of six bioactive components of Shen-Wu-Yi-Shen tablets in normal and chronic renal failure rats based on UPLC-TSQ-MS/MS. Journal of ethnopharmacology, 2023, Dec-05, Volume: 317 Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Creatinine; Drugs, Chinese Herbal; Emodin; Kidney Failure, Chronic; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tablets; Tandem Mass Spectrometry	2023
Active ingredients of Erhuang Quzhi Granules for treating non-alcoholic fatty liver disease based on the NF-κB/NLRP3 pathway. Fitoterapia, 2023, Volume: 171 Topics: Animals; Curcumin; Emodin; Inflammasomes; Molecular Docking Simulation; Molecular Structure; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease	2023