emodin has been researched along with imatinib mesylate in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, B; Chen, C; Chen, Y; Hu, J; Li, J; Liu, T; Qiu, B; Wang, W; Zheng, J; Zheng, Z | 1 |
| Hu, JD; Li, BJ; Lin, MH; Liu, TB; Wang, WF | 1 |
| Liu, BZ; Liu, YL; Shi, LQ; Shi, XJ; Wang, CG; Zeng, L; Zhong, L | 1 |
| Sun, GB; Wang, XY; Wang, YJ; Yan, F | 1 |
4 other study(ies) available for emodin and imatinib mesylate
| Article | Year |
|---|---|
Inhibition of 32Dp210 cells harboring T315I mutation by a novel derivative of emodin correlates with down-regulation of BCR-ABL and its downstream signaling pathways.
Topics: Apoptosis; Benzamides; Blotting, Western; Cell Proliferation; Colony-Forming Units Assay; Down-Regulation; Drug Resistance, Neoplasm; Emodin; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mutation; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2015 |
[Effect of A Novel Emodin Derivative on Chronic Myelogenous Leukemia K562 Cells and Imatinib-resistant K562/G01 Cells].
Topics: Apoptosis; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Emodin; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Phosphorylation | 2016 |
Emodin Exerts an Antiapoptotic Effect on Human Chronic Myelocytic Leukemia K562 Cell Lines by Targeting the PTEN/PI3K-AKT Signaling Pathway and Deleting BCR-ABL.
Topics: Antineoplastic Agents; Apoptosis; Biological Products; Cell Proliferation; Drug Resistance, Neoplasm; Emodin; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction | 2017 |
Emodin Inhibits Resistance to Imatinib by Downregulation of Bcr-Abl and STAT5 and Allosteric Inhibition in Chronic Myeloid Leukemia Cells.
Topics: Allosteric Regulation; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Emodin; Genes, abl; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Secondary; STAT5 Transcription Factor | 2020 |