emodin has been researched along with cx 4945 in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderes, K; Bliesath, J; Bourbon, P; Chen, TK; Chua, PC; Darjania, L; Drygin, D; Haddach, M; Ho, C; Michaux, J; Nagasawa, J; O'Brien, SE; Omori, M; Pierre, F; Proffitt, C; Rice, WG; Ryckman, DM; Schwaebe, MK; Siddiqui-Jain, A; Stansfield, R; Stefan, E; Streiner, N; Trent, K; Vialettes, A; Whitten, JP | 1 |
| Alvarez, L; Baratin, S; Bollacke, A; Desplat, V; Guillon, J; Jose, J; Le Borgne, M; Marchivie, M; Moreau, S; Pecci, A; Pinaud, N; Rimbault, C; Roche, S; Savrimoutou, S | 1 |
| Aichele, D; Bollacke, A; Bouaziz, Z; Cadena, SM; Daflon-Yunes, N; Di Pietro, A; Guillon, J; Jabor Gozzi, G; Jose, J; Lacoudre, A; Le Borgne, M; Marminon, C; Nacereddine, A; Pinaud, N; Valdameri, G; Winter, E; Zeinyeh, W | 1 |
| Chen, T; Chen, Y; Feng, F; Guo, Q; Lin, H; Liu, W; Liu, Z; Qiao, Y; Qu, W; Sun, H; Yang, H | 1 |
| Benveniste, EN; Gibson, SA | 1 |
1 review(s) available for emodin and cx 4945
| Article | Year |
|---|---|
Small molecule modulators targeting protein kinase CK1 and CK2.
Topics: Animals; Casein Kinase I; Casein Kinase II; Drug Discovery; Humans; Molecular Docking Simulation; Protein Kinase Inhibitors; Small Molecule Libraries | 2019 |
4 other study(ies) available for emodin and cx 4945
| Article | Year |
|---|---|
Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Binding, Competitive; Biological Availability; Casein Kinase II; Cell Line, Tumor; Dogs; Drug Screening Assays, Antitumor; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Inbred ICR; Mice, Nude; Models, Molecular; Naphthyridines; Neoplasm Transplantation; Phenazines; Rats; Structure-Activity Relationship; Transplantation, Heterologous | 2011 |
Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of the human protein kinase CK2.
Topics: Casein Kinase II; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Pyrroles; Quinoxalines; Structure-Activity Relationship | 2013 |
Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2 into selective inhibitors of the breast cancer resistance protein ABCG2.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Breast Neoplasms; Casein Kinase II; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; HEK293 Cells; Humans; Indoles; MCF-7 Cells; Mitoxantrone; Models, Chemical; Molecular Structure; Neoplasm Proteins; Protein Kinase Inhibitors | 2015 |
Protein Kinase CK2: An Emerging Regulator of Immunity.
Topics: Animals; Autoimmune Diseases; Casein Kinase II; Clinical Trials as Topic; Emodin; Humans; Immunity; Immunomodulation; Inflammation; Mice; Molecular Targeted Therapy; Multiple Sclerosis; Naphthyridines; Neoplasms; Phenazines; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells | 2018 |