emodin has been researched along with casein kinase ii in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 13 (48.15) | 29.6817 |
| 2010's | 12 (44.44) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, T; Chen, Y; Feng, F; Guo, Q; Lin, H; Liu, W; Liu, Z; Qiao, Y; Qu, W; Sun, H; Yang, H | 1 |
| Lee, CH; Lee, SK; Lee, YH; Yim, H | 1 |
| Battistutta, R; De Moliner, E; Papinutto, E; Pinna, LA; Sarno, S; Zanotti, G | 1 |
| Davies, SP; Donella-Deana, A; Meggio, F; Pinna, LA; Reddy, H; Ruzzene, M; Sarno, S; Shugar, D | 1 |
| Brunati, AM; Cesaro, L; Donella-Deana, A; Pinna, LA; Ruzzene, M; Sarno, S | 1 |
| Battistutta, R; De Moliner, E; Pinna, LA; Sarno, S; Zanotti, G | 1 |
| Channavajhala, P; Seldin, DC | 1 |
| Bech-Otschir, D; Berse, M; Dubiel, W; Dumdey, R; Henklein, P; Huang, X; Medalia, O; Schade, R; Sperling, J; Uhle, S; Waldron, R | 1 |
| Adachi, T; Fujii, S; Hirasawa, A; Kadowaki, T; Katsuma, S; Kobayashi, M; Koshimizu, TA; Miyamoto, Y; Nihei, H; Okuno, Y; Sekiya, Y; Shiojima, S; Tamura, M; Tsujimoto, G; Yamada, M; Yumura, W | 1 |
| Ahmed, K; Chan, CK; Grant, MB; Hinton, DR; Kabosova, A; Kramerov, AA; Ljubimov, AV; Montenarh, M; Pan, H; Penn, JS; Saghizadeh, M | 1 |
| Bjørling-Poulsen, M; Guerra, B; Olsen, BB | 1 |
| Bachmann, C; Götz, C; Montenarh, M | 1 |
| Issinger, OG; Klopffleisch, K; Niefind, K; Raaf, J | 1 |
| Kim, HR; Kim, J; Kim, K; Kim, SJ; Lee, KH | 1 |
| Guerra, B; Issinger, OG; Olsen, BB; Sandholt, IS | 1 |
| Eger, K; Gaunitz, F; Gebhardt, R; Götschel, F; Günther, R; Hecht, A; Hofmann, HJ; Kolander, J; Lerche, KS; Teich, L; Zellmer, S | 1 |
| Zhang, N; Zhong, R | 2 |
| Götz, C; Gratz, A; Jose, J | 1 |
| Battistutta, R; Lolli, G; Papinutto, E; Pinna, LA; Ranchio, A | 1 |
| An, WS; Kim, KH; Kim, SE; Lee, SM; Rha, SH; Rho, JH; Son, YK | 1 |
| Fuchi, N; Hirasawa, A; Hou, Z; Liu, N; Miyamoto, Y; Ohno, H; Oshida, K; Shi, J; Suzuki, Y; Takei, Y; Tsujimoto, G; Xiao, Y; Yamada, M; Yasue, M | 1 |
| Bollacke, A; Haidar, S; Jose, J; Meyers, A | 1 |
| Golczyk, H; Janeczko, M; Kubiński, K; Masłyk, M | 1 |
| Aponte, F; Boscán, BE; Bubis, J; Calabokis, M; Camargo, R; Uzcanga, GL | 1 |
| Benveniste, EN; Gibson, SA | 1 |
| Ahmed, AG; Ahn, AR; Ahn, SJ; Hussein, UK; Jang, KY; Kim, JR; Kim, KM; Moon, YJ; Park, HS; Park, SH; Song, Y | 1 |
1 review(s) available for emodin and casein kinase ii
| Article | Year |
|---|---|
Small molecule modulators targeting protein kinase CK1 and CK2.
Topics: Animals; Casein Kinase I; Casein Kinase II; Drug Discovery; Humans; Molecular Docking Simulation; Protein Kinase Inhibitors; Small Molecule Libraries | 2019 |
26 other study(ies) available for emodin and casein kinase ii
| Article | Year |
|---|---|
Emodin, an anthraquinone derivative isolated from the rhizomes of Rheum palmatum, selectively inhibits the activity of casein kinase II as a competitive inhibitor.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding, Competitive; Casein Kinase II; Emodin; Enzyme Inhibitors; Plants, Medicinal; Protein Serine-Threonine Kinases; Rheum | 1999 |
The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2.
Topics: Adenosine Triphosphate; Binding, Competitive; Casein Kinase II; Catalysis; Emodin; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Molecular Sequence Data; Plant Proteins; Protein Conformation; Protein Serine-Threonine Kinases; Structure-Activity Relationship | 2000 |
Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').
Topics: Adenosine Triphosphate; Amino Acid Substitution; Binding Sites; Binding, Competitive; Casein Kinase II; Emodin; Enzyme Inhibitors; Humans; Jurkat Cells; Protein Kinases; Protein Serine-Threonine Kinases; Staurosporine; Substrate Specificity; Triazoles | 2001 |
Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Casein Kinase II; Emodin; Enzyme Inhibitors; Escherichia coli; Heparin; Kinetics; Models, Molecular; Oligopeptides; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Conformation; Protein Serine-Threonine Kinases; Protein Subunits; Recombinant Proteins; Substrate Specificity; Tyrosine | 2001 |
Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole.
Topics: Adenosine Triphosphate; Binding Sites; Casein Kinase II; Emodin; Enzyme Inhibitors; Guanosine Triphosphate; Models, Molecular; Protein Serine-Threonine Kinases; Triazoles; Zea mays | 2001 |
Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis.
Topics: Animals; Apigenin; Blotting, Western; Casein Kinase II; Cell Division; Cells, Cultured; Emodin; Flavonoids; Glutathione Transferase; Lymphoma; Mice; Mice, Transgenic; Peptide Hydrolases; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Recombinant Fusion Proteins; T-Lymphocytes | 2002 |
Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome.
Topics: Adenosine Triphosphate; Casein Kinase II; COP9 Signalosome Complex; Curcumin; Dichlororibofuranosylbenzimidazole; DNA-Binding Proteins; Emodin; Enzyme Inhibitors; Erythrocytes; HeLa Cells; Humans; Multiprotein Complexes; Peptide Hydrolases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Subunits; Proteins; Proto-Oncogene Proteins c-jun; Recombinant Proteins; Resveratrol; Signal Transduction; Stilbenes; Substrate Specificity; Tumor Suppressor Protein p53; Ubiquitins | 2003 |
Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis.
Topics: Analysis of Variance; Animals; Apigenin; Blood Urea Nitrogen; Blotting, Western; Casein Kinase II; Creatinine; Emodin; Glomerulonephritis; Immune Sera; Immunohistochemistry; In Situ Nick-End Labeling; Kidney; Male; Oligodeoxyribonucleotides, Antisense; Oligonucleotide Array Sequence Analysis; Prednisolone; Protein Subunits; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Specific Pathogen-Free Organisms | 2005 |
Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina.
Topics: Angiogenesis Inhibitors; Animals; Astrocytes; Casein Kinase II; Drug Combinations; Emodin; Enzyme Inhibitors; Humans; Immunohistochemistry; Infant, Newborn; Mice; Molecular Sequence Data; Rats; Retina; Retinal Neovascularization; Retinopathy of Prematurity; Reverse Transcriptase Polymerase Chain Reaction; Somatostatin | 2006 |
Emodin negatively affects the phosphoinositide 3-kinase/AKT signalling pathway: a study on its mechanism of action.
Topics: Antineoplastic Agents, Phytogenic; Casein Kinase II; Emodin; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2007 |
Inhibition of protein kinase CK2 leads to a modulation of androgen receptor dependent transcription in prostate cancer cells.
Topics: Adenocarcinoma; Benzimidazoles; Blotting, Western; Casein Kinase II; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Emodin; Genes, Reporter; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptors, Androgen; Transcription, Genetic; Transfection | 2007 |
The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin.
Topics: Adenosine Triphosphate; Casein Kinase II; Catalytic Domain; Crystallography, X-Ray; Emodin; Humans; Models, Molecular; Molecular Conformation; Nucleotides; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Zea mays | 2008 |
Inhibition of casein kinase 2 enhances the death ligand- and natural kiler cell-induced hepatocellular carcinoma cell death.
Topics: Apoptosis; Carcinoma, Hepatocellular; Casein Kinase II; Cytoplasmic Granules; Cytotoxicity, Immunologic; Emodin; Fas Ligand Protein; Humans; Killer Cells, Natural; Liver Neoplasms; Protein Kinase Inhibitors; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2008 |
Resorufin: a lead for a new protein kinase CK2 inhibitor.
Topics: Apoptosis; Casein Kinase II; Cell Line, Tumor; Colorectal Neoplasms; Emodin; Humans; Inhibitory Concentration 50; Male; Oxazines; Prostatic Neoplasms; Protein Kinase Inhibitors; Signal Transduction | 2009 |
4-Aminoethylamino-emodin--a novel potent inhibitor of GSK-3beta--acts as an insulin-sensitizer avoiding downstream effects of activated beta-catenin.
Topics: Animals; Axin Protein; beta Catenin; Casein Kinase II; Cell Death; Cell Survival; Cells, Cultured; Cytoskeletal Proteins; Emodin; Fatty Acids; Glycogen; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hepatocytes; Humans; Inhibitory Concentration 50; Insulin; Mice; Models, Biological; Models, Molecular; Protein Kinase Inhibitors; Protein Stability; Rats; TCF Transcription Factors; Transcription, Genetic | 2010 |
Structural basis for decreased affinity of Emodin binding to Val66-mutated human CK2 alpha as determined by molecular dynamics.
Topics: Allosteric Regulation; Casein Kinase II; Emodin; Humans; Molecular Dynamics Simulation; Mutation, Missense; Protein Binding; Protein Conformation; Thermodynamics | 2010 |
A FRET-based microplate assay for human protein kinase CK2, a target in neoplastic disease.
Topics: Casein Kinase II; Emodin; Enzyme Assays; Fluorescence; Fluorescence Resonance Energy Transfer; Humans; Naphthalenesulfonates; Neoplasms; p-Dimethylaminoazobenzene; Pancreatic Elastase; Peptides; Phosphorylation; Protein Kinase Inhibitors; Sensitivity and Specificity; Triazoles | 2010 |
Docking and 3D-QSAR studies of 7-hydroxycoumarin derivatives as CK2 inhibitors.
Topics: Casein Kinase II; Chromones; Drug Design; Emodin; Humans; Ligands; Models, Molecular; Protein Conformation; Protein Kinase Inhibitors; Quantitative Structure-Activity Relationship; Umbelliferones | 2010 |
Structural and functional analysis of the flexible regions of the catalytic α-subunit of protein kinase CK2.
Topics: Amino Acid Motifs; Anthraquinones; Apoenzymes; Binding Sites; Casein Kinase II; Catalytic Domain; Crystallography, X-Ray; Emodin; Histidine; Humans; Models, Molecular; Plant Proteins; Protein Binding; Protein Kinase Inhibitors; Zea mays | 2012 |
The role of protein kinase CK2 in cyclosporine-induced nephropathy in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Casein Kinase II; Caspase 3; Caspase 7; Caspase 8; Cyclosporine; Diet, Sodium-Restricted; Disease Models, Animal; Emodin; Immunohistochemistry; Kidney; Kidney Diseases; Male; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 | 2013 |
The Effects of a Selective CK2 Inhibitor on Anti-glomerular Basement Membrane Glomerulonephritis in Rats.
Topics: Animals; Apoptosis; Blood Urea Nitrogen; Casein Kinase II; Creatinine; Emodin; Glomerulonephritis; Kidney Glomerulus; Male; Protein Kinase Inhibitors; Proteinuria; Pyrazines; Rats, Inbred WKY; Testis | 2015 |
Synthesis and biological evaluation of 2,6-di(furan-3-yl)anthracene-9, 10-dione as an inhibitor of human protein kinase CK2.
Topics: Adenosine Triphosphate; Anthraquinones; Antineoplastic Agents; Casein Kinase II; Catalytic Domain; Emodin; Humans; Hydrogen Bonding; Models, Molecular; Molecular Docking Simulation; Protein Kinase Inhibitors | 2015 |
Emodin, a natural inhibitor of protein kinase CK2, suppresses growth, hyphal development, and biofilm formation of Candida albicans.
Topics: Antifungal Agents; Biofilms; Candida albicans; Casein Kinase II; Emodin; Hyphae; Microbial Sensitivity Tests; Microscopy, Fluorescence | 2017 |
Interaction of tubulin and protein kinase CK2 in Trypanosoma equiperdum.
Topics: Antibodies, Monoclonal; Casein Kinase II; Emodin; Gene Expression Regulation; Guanosine Triphosphate; Molecular Weight; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Transport; Protozoan Proteins; Signal Transduction; Static Electricity; Trypanosoma; Tubulin | 2017 |
Protein Kinase CK2: An Emerging Regulator of Immunity.
Topics: Animals; Autoimmune Diseases; Casein Kinase II; Clinical Trials as Topic; Emodin; Humans; Immunity; Immunomodulation; Inflammation; Mice; Molecular Targeted Therapy; Multiple Sclerosis; Naphthyridines; Neoplasms; Phenazines; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells | 2018 |
CK2α/CSNK2A1 Induces Resistance to Doxorubicin through SIRT6-Mediated Activation of the DNA Damage Repair Pathway.
Topics: Adult; Apoptosis; Casein Kinase II; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Repair; Doxorubicin; Drug Resistance, Neoplasm; Emodin; Female; Humans; Kaplan-Meier Estimate; Male; Multivariate Analysis; Phosphorylation; Prognosis; Proportional Hazards Models; Regression Analysis; Sirtuins | 2021 |