emodin has been researched along with alloin in 141 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (13.48) | 18.7374 |
| 1990's | 9 (6.38) | 18.2507 |
| 2000's | 30 (21.28) | 29.6817 |
| 2010's | 53 (37.59) | 24.3611 |
| 2020's | 30 (21.28) | 2.80 |
| Authors | Studies |
|---|---|
| Atzler, K; Baqi, Y; Glänzel, M; Köse, M; Müller, CE | 1 |
| Autore, G; Capasso, F; Duraccio, MR; Mascolo, N | 1 |
| Baretton, G; Siegers, CP; Siemers, J | 1 |
| Livesey, JF; Perkins, SL | 1 |
| Bogoni, P; Masotti, P; Micali, G; Zonta, F | 1 |
| Koch, A | 1 |
| Cha, YN; Cheong, JC; Chung, JH; Lee, JY; Roh, HK | 1 |
| Scheibler, P | 1 |
| Amin, MA; Esmat, AY; Fahim, FA; Mady, EA | 1 |
| Bogoni, P; Procida, G; Saccù, D | 1 |
| Ahmad, SI; Ahmed, M; Akhtar, S; Dar, A; Faizi, S; Hasnain, SN; Hussain, SA; Qazi, A; Qazi, MH; Saleem, R; Siddiqui, BS | 1 |
| Barrantes, E; Guinea, M | 1 |
| Falvey, DE; Vath, P; Wamer, WG | 1 |
| Song, XR; Wang, DX; Wang, LY; Yang, GL | 1 |
| Lu, Y; Tan, C; Zhu, W | 1 |
| BEAL, JL; CHRISTENSEN, BV; MARY, NY | 1 |
| BERTRAM, J; BOHME, H | 1 |
| DURAND, M; PARIS, R | 1 |
| KRAUS, L | 1 |
| FAIRBAIRN, JW; MITAL, VK | 1 |
| BENNETT, E; CZARNECKI, RB; WORTHEN, LR | 1 |
| BAUMGARTNER, R; LEUPIN, K | 1 |
| FAIRBAIRN, JW; SIMIC, S | 2 |
| AWE, W; KUEMMELL, HJ | 2 |
| GERRITSMA, KW; RHEEDE VAN OUDTSHOORN, MC | 1 |
| GERRITSMA, KW; RHEEDEVANOUDTSHOORN, MC | 1 |
| MCCARTHY, TJ; PRICE, CH | 1 |
| BOEHMERT, H; JANIAK, B | 1 |
| Beppu, H; Chihara, T; Hoshino, M; Ida, C; Koike, T; Kuzuya, H; Shimpo, K | 1 |
| Hu, ZH; Li, JY; Shen, ZG; Wang, TX | 1 |
| Cao, H; Liu, Y | 1 |
| ElSohly, MA; Gul, W; Murphy, TP | 1 |
| Hua, YJ; Ma, XQ; Tian, B; Wang, GL | 1 |
| El-Gerzawy, SM; Esmat, AY; Rafaat, A | 1 |
| Li, F; Li, J; Wang, H; Wang, T; Yang, X | 1 |
| Bi, S; Kan, Y; Song, D; Tian, Y; Xu, D; Zhang, H; Zhou, X | 1 |
| Esmat, AY; Rio, MC; Tomasetto, C | 1 |
| Cao, X; Dong, Y; Huang, D; Zhao, H | 1 |
| Hu, ZH; Liao, HM; Shen, ZG; Sheng, XY | 1 |
| Boudreau, MD; Fu, PP; Xia, Q; Yin, JJ | 1 |
| Li, Q; Li, X; Pronin, AN; Tang, H; Xu, H; Zhang, L | 1 |
| Adzić, M; Nićiforović, A; Radojcić, MB; Spasić, SD | 1 |
| Bergamante, V; Ceschel, GC; Fini, A; Marazzita, S; Ronchi, C | 1 |
| Buenz, EJ | 1 |
| STONE, KG | 1 |
| Doi, Y; Hashimoto, N; Hosokawa, K; Imaida, K; Kuno, T; Matsuda, Y; Nabae, K; Saoo, K; Suzuki, S; Yamakawa, K; Yokohira, M | 1 |
| Kwon, HJ; Park, MY; Sung, MK | 2 |
| Caneva, E; Krpetić, Z; Porta, F; Scarì, G; Speranza, G | 1 |
| Ji, Y; Jia, J | 1 |
| Gopi, S; Kumar, S; Matharasi, DP; Narasimhan, S; Sivakumar, S | 1 |
| Bambagiotti-Alberti, M; Bartolucci, G; Coran, SA | 1 |
| PADILHA GONCALVES, A | 1 |
| GARDNER, JH | 1 |
| Guo, Y; Ji, R; Jiang, X; Lü, X; Wan, YF | 1 |
| Das, PK; Gantait, S; Mandal, N | 1 |
| Beninati, S; Facchiano, F; Lentini, A; Provenzano, B; Rossi, S; Tabolacci, C; Turcano, L | 1 |
| Li, G; Song, W; Wang, J; Xiao, X | 1 |
| Gulati, A; Gupta, M; Kiran, S; Singh, B; Tewari, R | 1 |
| Fani, M; Kohanteb, J | 1 |
| Ali, SA; Choudhary, RK; Galgut, JM | 1 |
| Bishayee, A; Harlev, E; Lansky, EP; Nevo, E; Ofir, R | 1 |
| Chobert, JM; Farivar, F; Ghaffari, SM; Ghamari, F; Haertlé, T; Johari, A; Moosavi-Movahedi, AA; Moosavi-Movahedi, F; Saboury, AA; Salami, M | 1 |
| Jackson, TC; Kochanek, PM; Verrier, JD | 1 |
| Castillo, S; Guillén, F; Martínez-Romero, D; Pérez-Aguilar, H; Serrano, M; Valero, D; Zapata, PJ | 1 |
| de Moraes, ML; Ferreira, M; Xavier, AC | 1 |
| Hamiza, OO; Khan, AQ; Khan, R; Lateef, A; Rehman, MU; Sultana, S; Tahir, M | 1 |
| Alpha Raj, M; Chaitanya Kumar, TV; Muralidhar, Y; Prasad, PE; Prasad, TN | 1 |
| Asres, K; Bisrat, D; Terefe, G; Tewabe, Y | 1 |
| Cui, Y; Li, Y; Qian, H; Wang, H; Xia, X; Yao, W; Ye, Q | 1 |
| Athayde, ML; Boligon, AA; Ferreira, J; Hoffmeister, C; Klafke, JZ; Oliveira, SM; Rossato, MF; Silva, CR; Silva, MA; Trevisan, G; Walker, CI | 1 |
| Cao, YY; Huan, N; Qian, H; Wang, HY; Xie, YF; Yao, WR; Zhong, Y | 1 |
| Esmat, AY; Khalil, SA; Said, MM | 1 |
| Avellone, G; Campisi, G; De Caro, V; Di Fede, O; Di Prima, G; Giannola, LI; Scaturro, AL; Sutera, FM | 1 |
| Liu, FC; Liu, FW; Tsai, HI; Wang, YR; Yu, HP | 1 |
| Chang, R; Li, Y; Qi, X; Sun, T; Wang, J; Wu, F; Yang, W; Yu, J; Zhang, W; Zhou, R | 1 |
| Andersen, K; Foderà, V; Jäger, AK; Jorgensen, L; Lobbens, ES; Nyberg, NT; van de Weert, M | 1 |
| Chung, HY; Chung, J; Heo, JY; Kim, S; Na, HS; Song, YR | 1 |
| Madhyastha, H; Madhyastha, R; Maruyama, M; Nakajima, Y; Pengjam, Y; Yamaguchi, Y | 1 |
| Fei, B; Gao, C; He, L; Hu, H; Lai, C; Lee, KI; Wang, W; Wang, X; Wang, Y; Xin, JH | 1 |
| Campas-Baypoli, ON; Cantú-Soto, EU; Cruz-Flores, P; López-Cervantes, J; Mariscal-Domínguez, MF; Sanches-Silva, A; Sánchez-Machado, DI | 1 |
| Babajanian, S; Chang, P; Gao, Q; Ingle, P; Kline, D; Ritruthai, V; Swanson, G | 1 |
| Beland, FA; Boudreau, MD; Bryant, MS; Felton, RP; Olson, GR; Tryndyak, VP | 1 |
| Choopani, R; Hajimehdipoor, H; Hamzeloo-Moghadam, M; Moein, E; Toliyat, T | 1 |
| Fan, K; Wan, L; Wang, J; Zhang, L | 1 |
| Mittal, AK; Mittal, S; Nigam, AK; Srivastava, A | 1 |
| Fan, P; Luo, X; Shi, M; Wei, X; Xie, W; Xu, N; Zhang, H; Zhang, Y | 1 |
| Ma, Y; Qi, Z; Sheng, L; Tang, T; Tao, H; Wang, Z; Zhang, Q; Zhang, Y | 1 |
| Madhyastha, H; Madhyastha, R; Maruyama, M; Nakajima, Y; Nurrahmah, QI; Pengjam, Y | 1 |
| Bai, XL; Hu, YD; Liao, X; Liu, YM; Xiao, MW; Yang, L | 1 |
| Chen, Z; Chu, J; Huang, S; Jing, K; Kong, J; Li, P; Lv, G; Quan, J; Wei, B; Wei, J | 1 |
| Jiang, Q; Li, J; Ma, Y; Qi, S; Qi, Z; Tang, T; Tao, H; Wang, Z; Zhang, Q | 1 |
| Jung, E; Kim, J | 1 |
| Chun, S; Gansukh, E; Gopal, J; Kim, DH; Muthu, M; Oh, JW; Paul, D | 1 |
| Reyes-Garcia, JG | 1 |
| García-García, E; Kaufer-Horwitz, M; Rodríguez-Flores, M | 1 |
| Bae, JS; Kim, KM; Ku, SK; Lee, C; Lee, W; Park, EK; Yang, S | 1 |
| Chen, L; Ma, F; Shen, C; Tang, Q; Wang, F; Wang, Z; Zheng, Y; Zhong, J; Zhu, J; Zhu, T | 1 |
| Baronchelli, F; Froldi, G; Grison, M; Marin, E | 1 |
| Bae, JS; Baek, MC; Jeong, GS; Ku, SK; Lee, W | 1 |
| Dai, C; Li, W; Peng, C; Shen, X; Yan, L; Yao, M; Yuan, Y; Zhang, W | 1 |
| Al-Dosari, MS; Alajmi, MF; Alam, P; Alqahtani, AS; Parvez, MK; Rehman, M | 1 |
| Çiçek, SS; Girreser, U; Ugolini, T | 1 |
| Chang, CS; Chen, TA; Chen, TC; Dutta, A; He, YC; Hseih, YC; Huang, CT; Huang, YL; Hung, CY; Lin, CY; Lin, YC; Shih, SR; Velu, AB | 1 |
| Bao, S; Chen, G; Chen, R; Cui, X; Niu, C; Sun, J; Xiao, S; Ye, W | 1 |
| Ma, C; Miao, W; Sun, R; Zhai, R | 1 |
| Cho, CW; Cho, IS; Kim, JH; Kim, KT; Lee, JI; Vinh, LB | 1 |
| Bae, JS; Lee, IC | 3 |
| Cai, T; Qi, S; Qi, Z; Tang, T; Tao, H; Wang, S; Wang, Z; Zhang, Q | 1 |
| Chen, H; Ding, J; Geng, Z; Jing, Y; Tian, HL; Wang, W; Yang, DX; Yuan, F | 1 |
| Li, Y; Peng, C; Shen, X; Yao, M; Yuan, Y; Zhang, W | 1 |
| Di, Z; Lei, J; Li, G; Li, Y; Shen, Y; Xv, G | 1 |
| Ebrahimzadeh, H; Mehrani, Z; Moradi, E | 1 |
| Gerogianni, M; Kanakis, CD; Kaparakou, EH; Maniati, M; Skotti, E; Tarantilis, PA; Vekrellis, K | 1 |
| Belemkar, S; Birari, L; Goyal, SN; Mahajan, UB; Ojha, S; Patil, CR; Patil, KR; Unger, B; Wagh, S | 1 |
| Bsoul, N; Chen, J; Chen, Z; Gao, W; Hu, X; Jiang, R; Li, B; Shao, Z; Xu, C; Zhang, C | 1 |
| Dong, H; Wang, H; Zhang, X | 1 |
| Fan, Y; Jia, H; Liang, Y; Loor, JJ; Lv, H; Sun, X; Xu, C; Xu, Q | 1 |
| Huang, W; Sun, M; Sun, W; Wang, Y; Wang, Z | 1 |
| Ayeni, EA; Chang, Q; Hu, YK; Liao, X; Ma, C; Wan, H; Yuan, H | 1 |
| Cheng, Y; Cui, Y; Guo, Y; Hu, B; Hua, H; Qian, H; Sheng, J; Zhang, W | 1 |
| Kulhari, U; Kumar, A; Kundu, S; Mugale, MN; Murty, US; Ram, C; Sahu, BD; Syed, AM | 1 |
| Cai, T; Chen, X; Cheng, J; Cheng, Z; Qi, S; Qi, Z; Wu, X | 1 |
| Clemens, RA; Hayes, AW; Pressman, P | 1 |
| Abdel-Moniem, MM; Esmat, AY; Hassan, AM; Said, MM | 1 |
| Chen, S; Chen, Y; Su, J; Xiao, J | 1 |
| Chavada, K; Ebert, MCCJC; Evoli, S; Ho, J; Kawall, A; Lewis, DSM; Mody, V; Rayalam, S; Sharma, A; Singh, A; Taval, S; Wills, S | 1 |
| Dangi, RS; Karalia, S; Kumar, V; Meena, VK; Sundd, M | 1 |
| Gao, J; Pan, J; Xie, G; Yang, S; Zhu, F | 1 |
| Fang, YX; Jiang, H; Liu, YQ; Shi, GF; Wang, Q; Yin, ZQ; Zhang, DJ; Zhang, J; Zheng, X | 1 |
| Ao, H; Chen, L; Liu, D; Peng, C; Tang, F; Wan, Y; Wu, JJ; Xia, J; Xu, JF; Yang, Y; Zhang, L | 1 |
| Chen, TT; Kong, XY; Yu, M; Zou, ZM | 1 |
| Ishii, Y; Takino, Y; Tanizawa, H | 1 |
| Akao, T; Che, QM; Hattori, M; Kobashi, K; Namba, T | 1 |
| Kan, K; Saito, K; Shindo, T; Takano, I; Uehara, S; Ushiyama, H; Yasuda, K | 1 |
| Alves, DS; Estepa, A; Micol, V; Pérez-Fons, L | 1 |
| Beppu, H; Chihara, T; Kaneko, T; Kuzuya, H; Ozaki, S; Shimpo, K; Sonoda, S; Tamai, I; Yamaji, S | 1 |
3 review(s) available for emodin and alloin
| Article | Year |
|---|---|
Anticancer potential of aloes: antioxidant, antiproliferative, and immunostimulatory attributes.
Topics: Adjuvants, Immunologic; Aloe; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Antioxidants; Emodin; Humans; Mannans; Medicine, Traditional; Plant Extracts; Plant Lectins; Plants, Medicinal | 2012 |
The potential health benefits of aloin from genus Aloe.
Topics: Aloe; Emodin; Plant Leaves; Plants, Medicinal | 2022 |
Can aloin develop to medicines or healthcare products?
Topics: Aloe; Anthraquinones; Anti-Inflammatory Agents; Antiviral Agents; Delivery of Health Care; Emodin; Laxatives | 2022 |
138 other study(ies) available for emodin and alloin
| Article | Year |
|---|---|
High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.
Topics: Anthraquinones; Binding, Competitive; Humans; Molecular Structure; Purinergic P2 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stereoisomerism; Structure-Activity Relationship | 2009 |
Effect of indomethacin on aloin and 1,8 dioxianthraquinone-induced production of prostaglandins in rat isolated colon.
Topics: Administration, Oral; Animals; Anthraquinones; Cathartics; Colon; Drug Interactions; Emodin; Indomethacin; Prostaglandins; Rats | 1983 |
Sennosides and aloin do not promote dimethylhydrazine-induced colorectal tumors in mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aloe; Animals; Anthraquinones; Carcinogens; Carcinoma; Cathartics; Colorectal Neoplasms; Dimethylhydrazines; Emodin; Incidence; Male; Mice; Plants, Medicinal; Random Allocation; Senna Extract; Sennosides | 1993 |
A rapid high-performance thin-layer chromatographic urine screen for laxative abuse.
Topics: Anthraquinones; Bisacodyl; Cathartics; Chromatography, High Pressure Liquid; Emodin; Female; Humans; Male; Middle Aged; Phenolphthalein; Phenolphthaleins; Substance-Related Disorders | 1993 |
High-performance liquid chromatographic profiles of aloe constituents and determination of aloin in beverages, with reference to the EEC regulation for flavouring substances.
Topics: Alcoholic Beverages; Aloe; Chromatography, High Pressure Liquid; Chromones; Emodin; European Union; Flavoring Agents; Glucosides; Kinetics; Molecular Structure; Plants, Medicinal; Spectrophotometry | 1995 |
Metabolism of aloin--the influence of nutrition.
Topics: Cathartics; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Emodin; Feces; Ferrous Compounds; Humans; Nutritional Physiological Phenomena | 1996 |
Acceleration of the alcohol oxidation rate in rats with aloin, a quinone derivative of Aloe.
Topics: Alanine Transaminase; Alcoholic Intoxication; Aloe; Animals; Anthraquinones; Aspartate Aminotransferases; Emodin; Ethanol; Female; Kinetics; Liver; Metabolic Clearance Rate; Oxidation-Reduction; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Triglycerides | 1996 |
Effects of aloin and some structure-related anthracene, anthracenone, and anthraquinone derivatives on lipid peroxidation in rat brain cortex homogenates.
Topics: Animals; Anthracenes; Anthraquinones; Antioxidants; Ascorbic Acid; Cerebral Cortex; Emodin; Free Radical Scavengers; Lipid Peroxidation; Rats; Thiobarbituric Acid Reactive Substances | 1997 |
Serum LDH and ALP isozyme activities in mice bearing solid Ehrlich carcinoma and/or treated with the maximum tolerated dose (MTD) of aloin.
Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Emodin; Female; Isoenzymes; L-Lactate Dehydrogenase; Mice | 1997 |
Aloe exudate: characterization by reversed phase HPLC and headspace GC-MS.
Topics: Alcoholic Beverages; Aloe; Chromatography, High Pressure Liquid; Chromones; Emodin; Gas Chromatography-Mass Spectrometry; Glucosides; Plant Leaves; Volatilization | 2001 |
Hypotensive effect of chemical constituents from Aloe barbadensis.
Topics: Aloe; Animals; Anthraquinones; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Emodin; Glucosides; Hypertension; Magnetic Resonance Spectroscopy; Phytotherapy; Plant Leaves; Plant Preparations; Plant Roots; Rats | 2001 |
Inhibition of collagenase and metalloproteinases by aloins and aloe gel.
Topics: Aloe; Aminopeptidases; Clostridium; Dose-Response Relationship, Drug; Emodin; Enzyme Inhibitors; Gels; Granulocytes; Humans; Matrix Metalloproteinase Inhibitors | 2003 |
In vitro studies on the photobiological properties of aloe emodin and aloin A.
Topics: Animals; Anthraquinones; Cattle; Cells, Cultured; Dermatitis, Phototoxic; DNA; DNA Damage; Emodin; Fibroblasts; Humans; Light; Oxidative Stress; Photosensitivity Disorders; Ultraviolet Rays | 2003 |
[Determination of the active components in Chinese herb Aloe vera L. var. chinensis (Haw.) Berger by capillary zone electrophoresis].
Topics: Aloe; Anthraquinones; Electrophoresis, Capillary; Emodin | 2000 |
Aloin, cinnamic acid and sophorcarpidine are potent inhibitors of tyrosinase.
Topics: Cinnamates; Cosmetics; Emodin; Enzyme Inhibitors; Humans; Hyperpigmentation; Monophenol Monooxygenase; Plant Preparations | 2002 |
A paper chromatographic study of aloe, aloin and of cascara sagrada.
Topics: Aloe; Chromatography, Paper; Emodin; Humans; Rhamnus | 1956 |
[Studies on the aloin of the cape aloe].
Topics: Aloe; Emodin; Humans | 1955 |
[Assay of aloe; photometric determination of aloin].
Topics: Aloe; Biological Assay; Cathartics; Emodin; Humans | 1956 |
[Quantitative determination of aloin in Aloe capensis. I. Determination by paper chromatography with planimetric evaluation of spot surfaces].
Topics: Aloe; Cathartics; Chromatography, Paper; Emodin | 1957 |
Vegetable purgatives containing anthracene derivatives. IX. An aloin-like substance in Rhamnus purshiana DC.
Topics: Anthracenes; Cathartics; Emodin; Rhamnus; Vegetables | 1958 |
The chromatographic behaviour of aloin.
Topics: Emodin; Glycosides; Humans | 1959 |
[On the constituents of the bark of Rhamnus purshiana (Cascara Sagrada Ph. Helv. V). 1. Assay for the presence of xanthorhamnin and the detection of aloin].
Topics: Biological Assay; Catecholamines; Emodin; Flavones; Glycosides; Health Services; Rhamnus | 1961 |
Vegetable purgatives containing anthracene derivatives. XI. Further work on the aloin-like substance of Rhamnus purshiana DC.
Topics: Anthracenes; Anthraquinones; Catecholamines; Cathartics; Emodin; Rhamnus; Vegetables | 1960 |
[Aloin, some observations on its constitution].
Topics: Anthracenes; Emodin | 1960 |
[Microanalytical determination of aloin].
Topics: Aloe; Chemistry Techniques, Analytical; Emodin | 1962 |
[On the occurrence of aloin in Aloe vera in addition to comparative studies with the fresh juice of Capealoe (Aloe ferox) and the dried extract prepared from it].
Topics: Aloe; Anthraquinones; Emodin; Humans | 1962 |
CHEMOTAXONOMY OF ASPHODELIODEAE (LILIACEAE) KRAUSE 1930. VI. ALOIN AND HOMONATALOIN IN ALOE SPECIES.
Topics: Aloe; Chemical Phenomena; Chemistry; Emodin; Liliaceae; Research | 1965 |
MICRO-DETERMINATION OF ALOIN IN SOME SOUTH AFRICAN ALOE SPECIES.
Topics: Alkaloids; Aloe; Chemistry, Pharmaceutical; Emodin; Microchemistry; Pharmacy; Research; South Africa | 1965 |
[A method for the quantitative determination of aloin].
Topics: Aloe; Emodin; Photometry | 1962 |
Radical-scavenging effects of Aloe arborescens Miller on prevention of pancreatic islet B-cell destruction in rats.
Topics: Alloxan; Aloe; Animals; Antioxidants; Cells, Cultured; Chromatography, High Pressure Liquid; Emodin; Free Radical Scavengers; Islets of Langerhans; Plant Extracts; Plant Leaves; Plant Preparations; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin | 2003 |
[Development of aloin cells and accumulation of anthraquinone in aloe leaf].
Topics: Aloe; Anthraquinones; Emodin; Plant Leaves; Plants, Medicinal | 2003 |
[Determination of aloin in aloes by HPLC].
Topics: Aloe; Chromatography, High Pressure Liquid; Emodin; Plants, Medicinal | 2003 |
Analysis of the anthraquinones aloe-emodin and aloin by gas chromatography/mass spectrometry.
Topics: Aloe; Anthraquinones; Emodin; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Reference Standards; Reproducibility of Results | 2004 |
[Relationship between antibacterial activity of aloe and its anthaquinone compounds].
Topics: Aloe; Anthraquinones; Anti-Bacterial Agents; Bacillus subtilis; Drugs, Chinese Herbal; Emodin; Escherichia coli; Plant Leaves; Plants, Medicinal; Proteus vulgaris; Pseudomonas aeruginosa; Staphylococcus aureus | 2003 |
DNA ploidy and S phase fraction of breast and ovarian tumor cells treated with a natural anthracycline analog (aloin).
Topics: Aloe; Breast Neoplasms; DNA; Emodin; Female; Humans; Ovarian Neoplasms; Ploidies; S Phase; Tumor Cells, Cultured | 2005 |
[Determination of aloin content in callus of Aloe vera var. chinensis].
Topics: Aloe; China; Chromatography, High Pressure Liquid; Culture Media; Drugs, Chinese Herbal; Emodin; Plant Growth Regulators; Plant Leaves; Plant Roots; Plant Stems; Plants, Medicinal; Tissue Culture Techniques | 2004 |
Spectroscopic characterization of effective components anthraquinones in Chinese medicinal herbs binding with serum albumins.
Topics: Anthraquinones; Binding Sites; Drugs, Chinese Herbal; Emodin; Humans; Models, Molecular; Molecular Structure; Serum Albumin; Serum Albumin, Bovine | 2005 |
Cytotoxicity of a natural anthraquinone (Aloin) against human breast cancer cell lines with and without ErbB-2: topoisomerase IIalpha coamplification.
Topics: Antigens, Neoplasm; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cyclin B; DNA Topoisomerases, Type II; DNA-Binding Proteins; Down-Regulation; Drug Resistance, Neoplasm; Emodin; Flow Cytometry; Gene Amplification; Humans; Mitosis; Receptor, ErbB-2 | 2006 |
[Preparative separation of aloin diastereoisomers by high-speed countercurrent chromatography combined with silica gel column chromatography].
Topics: Aloe; Anti-Bacterial Agents; Countercurrent Distribution; Drugs, Chinese Herbal; Emodin; Reference Standards; Silica Gel; Silicates; Silicon Dioxide; Spectrometry, Mass, Fast Atom Bombardment | 2006 |
[Ultracytochemical studies of aloin in Aloe arborescens leaves].
Topics: Aloe; Emodin; Microscopy, Electron, Transmission; Plant Leaves | 2006 |
Photo-irradiation of Aloe vera by UVA--formation of free radicals, singlet oxygen, superoxide, and induction of lipid peroxidation.
Topics: Aloe; Electron Spin Resonance Spectroscopy; Emodin; Free Radical Scavengers; Free Radicals; Linoleic Acids; Lipid Peroxidation; Plant Extracts; Reactive Oxygen Species; Superoxides; Ultraviolet Rays | 2007 |
Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.
Topics: Emodin; Humans; Phenylthiourea; Polymorphism, Single Nucleotide; Receptors, G-Protein-Coupled; Saccharin; Taste | 2007 |
Antitumor effects of a natural anthracycline analog (Aloin) involve altered activity of antioxidant enzymes in HeLaS3 cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Cycle; Cell Proliferation; Emodin; Female; HeLa Cells; Humans; NF-kappa B; Oxidoreductases; Uterine Cervical Neoplasms | 2007 |
Effect of vehicles on topical application of aloe vera and arnica montana components.
Topics: Administration, Cutaneous; Aloe; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arnica; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Diffusion; Emodin; Emulsions; Excipients; Gels; Humans; Permeability; Pharmaceutical Vehicles; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Guaiane; Skin Absorption; Swine | 2007 |
Aloin induces apoptosis in Jurkat cells.
Topics: Aloe; Anthraquinones; Apoptosis; Cell Cycle; Cell Death; Cell Division; Chromatography, High Pressure Liquid; Cytoplasmic Granules; Dietary Supplements; Emodin; Humans; Jurkat Cells; Mass Spectrometry; Mitochondrial Membranes | 2008 |
The estimation of aloin in pharmaceuticals.
Topics: Emodin; Humans | 1947 |
Equivocal colonic carcinogenicity of Aloe arborescens Miller var. natalensis berger at high-dose level in a Wistar Hannover rat 2-y study.
Topics: Aloe; Animals; Colonic Neoplasms; Diarrhea; Disease Models, Animal; Emodin; Female; Glucosides; Male; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Survival Rate | 2009 |
Evaluation of aloin and aloe-emodin as anti-inflammatory agents in aloe by using murine macrophages.
Topics: Aloe; Animals; Anthraquinones; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Emodin; Flavonols; Gene Expression Regulation, Enzymologic; Isoflavones; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; RNA, Messenger | 2009 |
Gold nanoparticles prepared using cape aloe active components.
Topics: Chromones; Emodin; Glucosides; Gold; HeLa Cells; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Molecular Structure; Plant Extracts; Transport Vesicles | 2009 |
Ultraviolet light absorption of an ophthalmic formulation with Aloe extracts.
Topics: Aloe; Emodin; Lactones; Ophthalmic Solutions; Plant Leaves; Polysaccharides; Sesquiterpenes; Spectrophotometry, Ultraviolet; Ultraviolet Rays | 2009 |
Synthesis of cytotoxic and antioxidant Schiff's base analogs of aloin.
Topics: Aloe; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Artemia; Biphenyl Compounds; Combinatorial Chemistry Techniques; Emodin; Molecular Structure; Picrates; Plants, Medicinal; Schiff Bases | 2010 |
Selective determination of aloin in different matrices by HPTLC densitometry in fluorescence mode.
Topics: Boric Acids; Calibration; Chromatography, Thin Layer; Densitometry; Emodin; High-Throughput Screening Assays; Molecular Structure; Reference Standards; Reproducibility of Results; Solutions; Spectrometry, Fluorescence; Time Factors | 2011 |
Professional contact dermatitis; positive contact test for podophyllin and aloin (with the presence of the patient).
Topics: Dermatitis, Contact; Emodin; Humans; Hypersensitivity; Industry; Occupations; Podophyllin | 1945 |
A comparison between certain reactions of the aloins and those of glucose.
Topics: Emodin; Glucose | 1945 |
Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model.
Topics: Aloe; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromones; Colitis; Colon; Diet; Dietary Supplements; Disease Models, Animal; Emodin; Gels; Glucosides; Interleukin-1beta; Leukotriene B4; Male; Peroxidase; Plant Preparations; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2011 |
[The protective effects of sodium selenite and aloin against ultraviolet A radiation].
Topics: Adolescent; Cells, Cultured; Dermis; Emodin; Fibroblasts; Humans; Male; Radiation-Protective Agents; Skin Aging; Sodium Selenite; Ultraviolet Rays; Young Adult | 2011 |
In vitro accelerated mass propagation and ex vitro evaluation of Aloe vera L. with aloin content and superoxide dismutase activity.
Topics: Aloe; Benzyl Compounds; Emodin; Indoleacetic Acids; Naphthaleneacetic Acids; Plant Roots; Plant Shoots; Purines; Superoxide Dismutase | 2011 |
Aloin enhances cisplatin antineoplastic activity in B16-F10 melanoma cells by transglutaminase-induced differentiation.
Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Drug Synergism; Emodin; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Spermine; Transglutaminases | 2013 |
Microwave-assisted extraction performed in low temperature and in vacuo for the extraction of labile compounds in food samples.
Topics: Ascorbic Acid; beta Carotene; Chromatography, High Pressure Liquid; Cold Temperature; Emodin; Food Analysis; Kinetics; Microwaves; Xanthophylls | 2012 |
Isolation and identification of phosphate solubilizing bacteria able to enhance the growth and aloin-A biosynthesis of Aloe barbadensis Miller.
Topics: Aloe; Bacteria; DNA, Bacterial; DNA, Ribosomal; Emodin; Phosphates; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Soil; Soil Microbiology | 2012 |
Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria.
Topics: Aggregatibacter actinomycetemcomitans; Aloe; Bacteroides; Colony Count, Microbial; Dental Caries; Emodin; Gels; Humans; Microbial Sensitivity Tests; Periodontal Diseases; Plant Extracts; Plant Leaves; Porphyromonas gingivalis; Streptococcus mutans | 2012 |
On the novel action of melanolysis by a leaf extract of Aloe vera and its active ingredient aloin, potent skin depigmenting agents.
Topics: Aloe; Animals; Bufonidae; Cells, Cultured; Emodin; Hyperpigmentation; Melanophores; Pigmentation; Plant Extracts | 2012 |
Synergic study of α-glucosidase inhibitory action of aloin and its antioxidant activity with and without camel β-casein and its peptides.
Topics: Aloe; alpha-Glucosidases; Animals; Antioxidants; Camelus; Caseins; Emodin; Glycoside Hydrolase Inhibitors; Hydrolysis; Linear Models; Milk; Peptides | 2013 |
Anthraquinone-2-sulfonic acid (AQ2S) is a novel neurotherapeutic agent.
Topics: Animals; Anthraquinones; Apoptosis; Caspases; Cell Survival; Cells, Cultured; Chromones; Emodin; Hydrogen Peroxide; Lipid Peroxidation; Morpholines; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Staurosporine | 2013 |
Is it possible to increase the aloin content of Aloe vera by the use of ultraviolet light?
Topics: Aloe; Botrytis; Chlorophyll; Emodin; Fungicides, Industrial; Penicillium; Plant Leaves; Ultraviolet Rays | 2013 |
Immobilization of aloin encapsulated into liposomes in layer-by-layer films for transdermal drug delivery.
Topics: Absorption; Administration, Cutaneous; Chemistry, Pharmaceutical; Drug Delivery Systems; Emodin; Liposomes; Phosphatidylglycerols; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2013 |
Chemopreventive effects of aloin against 1,2-dimethylhydrazine-induced preneoplastic lesions in the colon of Wistar rats.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Colonic Diseases; Emodin; Gene Expression Regulation, Enzymologic; Male; Precancerous Conditions; Rats; Rats, Wistar | 2014 |
Evaluation of therapeutic potential of nanosilver particles synthesised using aloin in experimental murine mastitis model.
Topics: Animals; Antioxidants; Body Weight; Disease Models, Animal; Drug Design; Emodin; Female; Mastitis; Metal Nanoparticles; Mice; Phylogeny; Silver; Staphylococcal Infections | 2013 |
Antitrypanosomal activity of aloin and its derivatives against Trypanosoma congolense field isolate.
Topics: Animals; Anthraquinones; Diminazene; Dose-Response Relationship, Drug; Emodin; Female; Mice; Molecular Structure; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2014 |
Aloin protects against chronic alcoholic liver injury via attenuating lipid accumulation, oxidative stress and inflammation in mice.
Topics: Animals; Antioxidants; Biomarkers; Cytokines; Disease Models, Animal; Emodin; Hepatitis, Alcoholic; Lipid Metabolism; Lipid Peroxidation; Liver Function Tests; Male; Mice, Inbred Strains; Oxidative Stress | 2014 |
Anti-inflammatory and antioxidant effects of Aloe saponaria Haw in a model of UVB-induced paw sunburn in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Chromatography, High Pressure Liquid; Disease Models, Animal; Emodin; Inflammation; Male; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Saponaria; Silver Sulfadiazine; Skin; Sunburn; Time Factors; Ultraviolet Rays | 2014 |
[Structural characterization and spectroscopic analysis of the aloin].
Topics: Emodin; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Vibration | 2014 |
Aloin: a natural antitumor anthraquinone glycoside with iron chelating and non-atherogenic activities.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cardiotoxicity; Doxorubicin; Emodin; Glycosides; Heart; Iron; Iron Chelating Agents; Kidney; Kidney Function Tests; Lipids; Male; Organ Size; Rats; Spleen | 2015 |
Aloin delivery on buccal mucosa: ex vivo studies and design of a new locoregional dosing system.
Topics: Acrylic Resins; Adhesiveness; Aloe; Animals; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Liberation; Emodin; Mouth Mucosa; Permeability; Polymers; Reproducibility of Results; Swine; Tablets | 2015 |
Aloin Protects Skin Fibroblasts from Heat Stress-Induced Oxidative Stress Damage by Regulating the Oxidative Defense System.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Cell Line; Cell Proliferation; Cell Survival; Deoxyguanosine; Emodin; Fibroblasts; Gene Expression Regulation; Glutathione; Hot Temperature; Humans; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Skin; Superoxide Dismutase | 2015 |
Protective effects of aloin on oxygen and glucose deprivation-induced injury in PC12 cells.
Topics: Animals; bcl-2-Associated X Protein; Calcium; Caspase 3; Cell Hypoxia; Dose-Response Relationship, Drug; Emodin; Flow Cytometry; Gene Expression Regulation; Glucose; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidative Stress; Oxides; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Sodium Compounds; Thiazolidinediones; Time Factors | 2016 |
The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products--A Study Using Aloin and Insulin.
Topics: Anthraquinones; Benzothiazoles; Biological Products; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Emodin; Excipients; Fluorescent Dyes; Glucosides; Insulin; Microscopy, Electron, Transmission; Oxidation-Reduction; Protein Stability; Proteolysis; Solutions; Spectrometry, Fluorescence; Thiazoles | 2016 |
Aloin Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.
Topics: Cells, Cultured; Emodin; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; KB Cells; Mouth Diseases; p38 Mitogen-Activated Protein Kinases | 2016 |
NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells.
Topics: Aloe; Animals; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Emodin; Humans; I-kappa B Kinase; I-kappa B Proteins; Macrophages; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Osteoclasts; Osteoporosis; Phytotherapy; Plant Extracts; RANK Ligand; RAW 264.7 Cells | 2016 |
Antibacterial modification of an injectable, biodegradable, non-cytotoxic block copolymer-based physical gel with body temperature-stimulated sol-gel transition and controlled drug release.
Topics: Anti-Bacterial Agents; Biodegradation, Environmental; Body Temperature; Cathartics; Cell Survival; Delayed-Action Preparations; Drug Liberation; Emodin; Epidermis; Escherichia coli; Gels; Humans; Hydrophobic and Hydrophilic Interactions; Injections; L-Lactate Dehydrogenase; Micelles; Phase Transition; Polyesters; Polyethylene Glycols; Skin, Artificial; Staphylococcus aureus; Transition Temperature | 2016 |
An HPLC Procedure for the Quantification of Aloin in Latex and Gel from Aloe barbadensis Leaves.
Topics: Aloe; Chromatography, High Pressure Liquid; Emodin; Latex; Limit of Detection; Linear Models; Plant Extracts; Plant Leaves; Reproducibility of Results | 2017 |
Quantitative Analysis of Aloins and Aloin-Emodin in Aloe Vera Raw Materials and Finished Products Using High-Performance Liquid Chromatography: Single-Laboratory Validation, First Action 2016.09.
Topics: Aloe; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Emodin | 2017 |
From the Cover: Aloin, a Component of the Aloe Vera Plant Leaf, Induces Pathological Changes and Modulates the Composition of Microbiota in the Large Intestines of F344/N Male Rats.
Topics: Aloe; Animals; Colon; Dose-Response Relationship, Drug; Emodin; Feces; Gastrointestinal Microbiome; Growth; Male; Plant Extracts; Plant Leaves; Rats; Rats, Inbred F344 | 2017 |
Formulation of an aloe-based product according to Iranian traditional medicine and development of its analysis method.
Topics: Aloe; Cinnamomum; Drug Compounding; Emodin; Flowers; Fruit; Herbal Medicine; Iran; Medicine, Traditional; Nardostachys; Phytotherapy; Piper; Pistacia; Plant Bark; Rhizome; Rosa; Tablets | 2017 |
Aloin promotes A549 cell apoptosis via the reactive oxygen species‑mitogen activated protein kinase signaling pathway and p53 phosphorylation.
Topics: A549 Cells; Animals; Apoptosis; Cell Proliferation; Emodin; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mitogen-Activated Protein Kinase 1; Neoplasm Proteins; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53 | 2017 |
Role of aloin in the modulation of certain immune parameters in skin mucus of an Indian major carp, Labeo rohita.
Topics: Adjuvants, Immunologic; Animals; Carps; Emodin; Immunity, Innate; Injections, Intraperitoneal; Mucus; Random Allocation; Skin | 2018 |
Aloin Suppresses Lipopolysaccharide-Induced Inflammatory Response and Apoptosis by Inhibiting the Activation of NF-κB.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Survival; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Emodin; Inflammation; Inflammation Mediators; Lipopolysaccharides; Macrophages; Mice; Models, Biological; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Protein Transport; Signal Transduction; Transcription Factor RelA | 2018 |
Aloin suppresses lipopolysaccharide‑induced inflammation by inhibiting JAK1‑STAT1/3 activation and ROS production in RAW264.7 cells.
Topics: Animals; Emodin; Inflammation; Janus Kinase 1; Lipopolysaccharides; Mice; RAW 264.7 Cells; Reactive Oxygen Species; STAT1 Transcription Factor; STAT3 Transcription Factor | 2018 |
The pivotal role of microRNA-21 in osteoclastogenesis inhibition by anthracycline glycoside aloin.
Topics: Animals; Anthracyclines; Emodin; Glycosides; Humans; Mice; MicroRNAs; Osteoclasts; Osteogenesis; Transfection | 2019 |
Rapid quantification of aloin A and B in aloe plants and aloe-containing beverages, and pharmaceutical preparations by microchip capillary electrophoresis with laser induced fluorescence detection.
Topics: Aloe; Beverages; Electrophoresis, Microchip; Emodin; Fluorescence; Lasers; Molecular Conformation; Plant Extracts; Spectrometry, Fluorescence | 2018 |
Aloin promotes osteogenesis of bone-marrow-derived mesenchymal stem cells via the ERK1/2-dependent Runx2 signaling pathway.
Topics: Animals; Bone Marrow; Cell Differentiation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Emodin; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Mesenchymal Stem Cells; Osteogenesis; Rats; Rats, Sprague-Dawley; Signal Transduction | 2019 |
[Aloin induces apoptosis
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Emodin; Fluorescent Dyes; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Stomach Neoplasms | 2018 |
Aloin Inhibits Müller Cells Swelling in a Rat Model of Thioacetamide-Induced Hepatic Retinopathy.
Topics: Ammonia; Animals; Aquaporin 4; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Emodin; Ependymoglial Cells; Hepatic Encephalopathy; Liver; Male; Potassium Channels, Inwardly Rectifying; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Thioacetamide | 2018 |
Ultrasound mediated accelerated Anti-influenza activity of Aloe vera.
Topics: Aloe; Animals; Anthraquinones; Antiviral Agents; Cell Line; Dogs; Emodin; Flavonoids; Madin Darby Canine Kidney Cells; Orthomyxoviridae; Phenol; Plant Extracts; Plant Leaves; Plants, Medicinal; Solvents; Ultrasonic Waves | 2018 |
Safety of drug combinations based on psychoactive agents in the treatment of obesity (A reply by the authors).
Topics: Atropine; Diazepam; Drug Combinations; Emodin; Humans; Obesity; Phenylpropanolamine; Psychotropic Drugs; Triiodothyronine | 2019 |
Safety of drug combinations based on psychoactive agents in the treatment of obesity.
Topics: Atropine; Diazepam; Drug Combinations; Emodin; Humans; Obesity; Phenylpropanolamine; Psychotropic Drugs; Triiodothyronine | 2019 |
Aloin reduces inflammatory gene iNOS via inhibition activity and p-STAT-1 and NF-κB.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Emodin; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Lung Diseases; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Plant Extracts; STAT1 Transcription Factor; Tumor Necrosis Factor-alpha | 2019 |
Aloin attenuates cognitive impairment and inflammation induced by d-galactose via down-regulating ERK, p38 and NF-κB signaling pathway.
Topics: Animals; Brain; Cognitive Dysfunction; Cytokines; Down-Regulation; Emodin; Galactose; Glutathione; Male; MAP Kinase Signaling System; Maze Learning; Mice, Inbred C57BL; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Superoxide Dismutase | 2019 |
Antiglycation Activity and HT-29 Cellular Uptake of Aloe-Emodin, Aloin, and
Topics: Aloe; Anthraquinones; Biphenyl Compounds; Cell Survival; Emodin; Flavonoids; Glycosylation; HT29 Cells; Humans; Hypoglycemic Agents; Methanol; Phenols; Phytochemicals; Picrates; Plant Extracts | 2019 |
Renal protective effects of aloin in a mouse model of sepsis.
Topics: Animals; Cell Line; Emodin; I-kappa B Proteins; Interleukin-6; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Protective Agents; Sepsis; Tumor Necrosis Factor-alpha | 2019 |
Study of the aqueous extract of Aloe vera and its two active components on the Wnt/β-catenin and Notch signaling pathways in colorectal cancer cells.
Topics: Aloe; Animals; beta Catenin; Cell Line; Cell Proliferation; Chromones; Colorectal Neoplasms; Emodin; Glucosides; Humans; Mice; Plant Extracts; Receptors, Notch; Signal Transduction; Wnt Proteins | 2019 |
The anti-hepatitis B virus therapeutic potential of anthraquinones derived from Aloe vera.
Topics: Aloe; Anthraquinones; Antiviral Agents; Cell Line; Emodin; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Humans; Phytotherapy; Plant Extracts | 2019 |
Quality control of Aloe vera (Aloe barbadensis) and Aloe ferox using band-selective quantitative heteronuclear single quantum correlation spectroscopy (bs-qHSQC).
Topics: Aloe; Emodin; Quality Control; Spectrum Analysis | 2019 |
Effect of aloin on viral neuraminidase and hemagglutinin-specific T cell immunity in acute influenza.
Topics: Aloe; Animals; Antiviral Agents; Cell Line; Drug Resistance, Viral; Emodin; Hemagglutinins; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuraminidase; Oseltamivir; Plant Leaves; T-Lymphocytes; Viral Proteins | 2019 |
UHPLC-MS/MS method for the quantification of aloin-A in rat plasma and its application to a pharmacokinetic study.
Topics: Administration, Oral; Animals; Anthraquinones; Biological Availability; Chromatography, High Pressure Liquid; Emodin; Male; Plant Extracts; Plasma; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry | 2020 |
Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Drug Synergism; Emodin; Female; Hep G2 Cells; Humans; Liver Neoplasms; Metformin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2020 |
An investigation of the inhibitory mechanism of α-glucosidase by chysalodin from Aloe vera.
Topics: Aloe; alpha-Glucosidases; Carbon-13 Magnetic Resonance Spectroscopy; Emodin; Enzyme Assays; Fluorescence; Glycoside Hydrolase Inhibitors; Kinetics; Proton Magnetic Resonance Spectroscopy | 2020 |
Inhibitory effects of aloin on TGFBIp-mediated septic responses.
Topics: Animals; Emodin; Extracellular Matrix Proteins; Human Umbilical Vein Endothelial Cells; Mice; Mice, Inbred C57BL; Molecular Structure; Transforming Growth Factor beta | 2021 |
Aloin Inhibits the Proliferation and Migration of Gastric Cancer Cells by Regulating NOX2-ROS-Mediated Pro-Survival Signal Pathways.
Topics: Cell Movement; Cell Proliferation; Emodin; Humans; NADPH Oxidase 2; Reactive Oxygen Species; Signal Transduction; Stomach Neoplasms; Survival Analysis; Tumor Cells, Cultured | 2020 |
Suppressive effects of aloin on polyphosphate-mediated vascular inflammatory responses.
Topics: Animals; Emodin; Human Umbilical Vein Endothelial Cells; Mice; Mice, Inbred C57BL; Molecular Structure; NF-kappa B; Polyphosphates; Tumor Necrosis Factor-alpha | 2021 |
Aloin Protects Against Blood-Brain Barrier Damage After Traumatic Brain Injury in Mice.
Topics: Animals; Blood-Brain Barrier; Brain Injuries, Traumatic; Disease Models, Animal; Emodin; Endothelial Cells; Male; Mice; Mice, Inbred C57BL; Stress, Mechanical | 2020 |
Post-transcriptional regulation activity through alternative splicing involved in the effects of Aloe vera on the Wnt/β-catenin and Notch pathways in colorectal cancer cells.
Topics: Aloe; Alternative Splicing; beta Catenin; Carcinogenesis; Cell Line, Tumor; Chromones; Colorectal Neoplasms; Emodin; Glucosides; Humans; Plant Extracts; Receptors, Notch; RNA Processing, Post-Transcriptional; Signal Transduction; Wnt Proteins | 2020 |
Aloin suppresses lipopolysaccharide-induced acute lung injury by inhibiting NLRP3/NF-κB via activation of SIRT1 in mice.
Topics: Acute Lung Injury; Aloe; Animals; Dose-Response Relationship, Drug; Emodin; Female; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Neutrophils; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Sirtuin 1 | 2020 |
Use of aloin-based and rosin-based electrospun nanofibers as natural nanosorbents for the extraction of polycyclic aromatic hydrocarbons and phenoxyacetic acid herbicides by microextraction in packed syringe method prior to GC-FID detection.
Topics: Adsorption; Emodin; Flame Ionization; Herbicides; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Nanofibers; Polycyclic Aromatic Hydrocarbons; Resins, Plant; Seawater; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2020 |
Quantitative determination of aloin, antioxidant activity, and toxicity of Aloe vera leaf gel products from Greece.
Topics: Aliivibrio fischeri; Aloe; Antioxidants; Cell Line; Chromatography, High Pressure Liquid; Emodin; Greece; Humans; Plant Extracts; Plant Leaves; Plant Preparations | 2021 |
Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines.
Topics: Animals; Antibiotics, Antineoplastic; Cardiotoxicity; Cathartics; Cytokines; Doxorubicin; Emodin; Inflammation Mediators; Male; Oxidative Stress; Rats; Rats, Wistar | 2020 |
Inhibition of PI3K/Akt/NF-κB signaling by Aloin for ameliorating the progression of osteoarthritis: In vitro and in vivo studies.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Chondrocytes; Disease Models, Animal; Emodin; Extracellular Matrix; Interleukin-1beta; Joints; Male; Mice, Inbred C57BL; Molecular Docking Simulation; NF-kappa B; Osteoarthritis; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction | 2020 |
Inhibition of NOX2 contributes to the therapeutic effect of aloin on traumatic brain injury.
Topics: Animals; Brain; Brain Injuries, Traumatic; Cytokines; Emodin; Insulin-Like Growth Factor I; Maze Learning; Mice; NADPH Oxidase 2; Oxidative Stress; PC12 Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2020 |
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling.
Topics: Amino Acids; Animals; Apoptosis; Biomarkers; Choline Deficiency; Diet; Dietary Fats; Emodin; Gene Expression Regulation; Heme Oxygenase-1; Inflammation; Liver; Male; Membrane Proteins; Mice; Mice, Knockout; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease | 2021 |
Aloin antagonizes stimulated ischemia/reperfusion-induced damage and inflammatory response in cardiomyocytes by activating the Nrf2/HO-1 defense pathway.
Topics: Animals; Cell Line; Emodin; Heme Oxygenase-1; Inflammation; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Rats; Reperfusion Injury | 2021 |
Fishing of α-Glucosidase's Ligands from
Topics: Aloe; alpha-Glucosidases; Cathartics; Emodin; Enzymes, Immobilized; Glucosides; Ligands; Magnetite Nanoparticles; Plant Extracts | 2021 |
The Intervention and Mechanism of Action for Aloin against Subchronic Aflatoxin B1 Induced Hepatic Injury in Rats.
Topics: Aflatoxin B1; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Disease Models, Animal; Down-Regulation; Emodin; Interleukin-1beta; Lipid Peroxidation; Liver; Male; Rats | 2021 |
Aloin alleviates pathological cardiac hypertrophy via modulation of the oxidative and fibrotic response.
Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Cardiomegaly; Cathartics; Emodin; Fibrosis; Isoproterenol; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2022 |
[Aloin inhibits lactate-induced proliferation and migration of gastric cancer cells by downregulating HMGB1 expression].
Topics: Cell Line, Tumor; Cell Proliferation; Emodin; Gene Expression Regulation, Neoplastic; HMGB1 Protein; Humans; Lactic Acid; Stomach Neoplasms | 2021 |
The absence of genotoxicity of a mixture of aloin A and B and a commercial aloe gel beverage.
Topics: Aloe; Beverages; DNA Damage; Emodin; Plant Extracts | 2022 |
Iron supplementation ameliorates aloin-induced iron deficiency anemia in rats.
Topics: Anemia, Iron-Deficiency; Animals; Dietary Supplements; Emodin; Erythropoiesis; Glycosides; Hepcidins; Iron; Iron Deficiencies; Liver; Rats; Receptors, Transferrin; Spleen | 2022 |
Inhibitory effects of aloin on lipopolysaccharide-induced severe inflammatory responses.
Topics: Animals; Anti-Inflammatory Agents; Cell Adhesion Molecules; Emodin; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Molecular Structure; NF-kappa B; Tumor Necrosis Factor-alpha | 2022 |
Aloin isoforms (A and B) selectively inhibits proteolytic and deubiquitinating activity of papain like protease (PLpro) of SARS-CoV-2 in vitro.
Topics: Animals; Binding Sites; Cell Survival; Chlorocebus aethiops; Coronavirus 3C Proteases; Coronavirus Papain-Like Proteases; COVID-19; Emodin; Humans; Molecular Dynamics Simulation; Protein Isoforms; SARS-CoV-2; Vero Cells | 2022 |
Structural and mechanistic insights into modulation of α-Synuclein fibril formation by aloin and emodin.
Topics: alpha-Synuclein; Amyloid; Emodin; Humans; Parkinson Disease | 2022 |
Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Aloin Against Gastric Cancer.
Topics: Emodin; Humans; Molecular Docking Simulation; Network Pharmacology; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Stomach Neoplasms | 2022 |
Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the Notch signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Emodin; Interleukin-10; Interleukin-6; Intestinal Mucosa; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Occludin; Prospective Studies; Signal Transduction; Tight Junction Proteins; Tumor Necrosis Factor-alpha; Water | 2022 |
In vivo metabolism combined network pharmacology to identify anti-constipation constituents in Aloe barbadensis Mill.
Topics: Aloe; Animals; Constipation; Emodin; Network Pharmacology; Plant Extracts; Rats; Tandem Mass Spectrometry | 2024 |
Studies of aloe. V. Mechanism of cathartic effect. (4).
Topics: Aloe; Animals; Anthracenes; Anthraquinones; Body Water; Cathartics; Chromatography, Thin Layer; Densitometry; Emodin; Feces; Intestinal Mucosa; Male; Mucus; Peristalsis; Plants, Medicinal; Rats; Rats, Wistar | 1994 |
A purgative action of barbaloin is induced by Eubacterium sp. strain BAR, a human intestinal anaerobe, capable of transforming barbaloin to aloe-emodin anthrone.
Topics: Animals; Anthracenes; Anthraquinones; Cathartics; Culture Media; Diarrhea; Emodin; Eubacterium; Feces; Intestines; Male; Rats; Rats, Wistar | 1996 |
[Contents of barbaloin-related compounds in aloe drinks and their change during storage].
Topics: Aloe; Anthracenes; Anthraquinones; Emodin; Food Analysis; Food Preservation; Temperature; Time Factors | 2002 |
The quantitative conversion of barbaloin to aloe-emodin and its application to the evaluation of aloes.
Topics: Aloe; Anthracenes; Anthraquinones; Emodin; Humans | 1963 |
Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin.
Topics: Anthracenes; Anthraquinones; Drug Delivery Systems; Emodin; Liposomes; Membranes; Phosphatidylglycerols; Spectrometry, Fluorescence; Temperature | 2004 |
Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice: investigation on hypoglycemic action and systemic absorption dynamics of aloe components.
Topics: Aloe; Animals; Anthracenes; Blood Glucose; Diabetes Mellitus, Experimental; Diet; Emodin; Female; Glucosides; Hypoglycemic Agents; Insulin; Intestinal Absorption; Islets of Langerhans; Mice; Mice, Inbred ICR; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tissue Distribution | 2006 |