emodin and alloin

emodin has been researched along with alloin in 141 studies

Research

Studies (141)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (13.48)	18.7374
1990's	9 (6.38)	18.2507
2000's	30 (21.28)	29.6817
2010's	53 (37.59)	24.3611
2020's	30 (21.28)	2.80

Authors

Authors	Studies
Atzler, K; Baqi, Y; Glänzel, M; Köse, M; Müller, CE	1
Autore, G; Capasso, F; Duraccio, MR; Mascolo, N	1
Baretton, G; Siegers, CP; Siemers, J	1
Livesey, JF; Perkins, SL	1
Bogoni, P; Masotti, P; Micali, G; Zonta, F	1
Koch, A	1
Cha, YN; Cheong, JC; Chung, JH; Lee, JY; Roh, HK	1
Scheibler, P	1
Amin, MA; Esmat, AY; Fahim, FA; Mady, EA	1
Bogoni, P; Procida, G; Saccù, D	1
Ahmad, SI; Ahmed, M; Akhtar, S; Dar, A; Faizi, S; Hasnain, SN; Hussain, SA; Qazi, A; Qazi, MH; Saleem, R; Siddiqui, BS	1
Barrantes, E; Guinea, M	1
Falvey, DE; Vath, P; Wamer, WG	1
Song, XR; Wang, DX; Wang, LY; Yang, GL	1
Lu, Y; Tan, C; Zhu, W	1
BEAL, JL; CHRISTENSEN, BV; MARY, NY	1
BERTRAM, J; BOHME, H	1
DURAND, M; PARIS, R	1
KRAUS, L	1
FAIRBAIRN, JW; MITAL, VK	1
BENNETT, E; CZARNECKI, RB; WORTHEN, LR	1
BAUMGARTNER, R; LEUPIN, K	1
FAIRBAIRN, JW; SIMIC, S	2
AWE, W; KUEMMELL, HJ	2
GERRITSMA, KW; RHEEDE VAN OUDTSHOORN, MC	1
GERRITSMA, KW; RHEEDEVANOUDTSHOORN, MC	1
MCCARTHY, TJ; PRICE, CH	1
BOEHMERT, H; JANIAK, B	1
Beppu, H; Chihara, T; Hoshino, M; Ida, C; Koike, T; Kuzuya, H; Shimpo, K	1
Hu, ZH; Li, JY; Shen, ZG; Wang, TX	1
Cao, H; Liu, Y	1
ElSohly, MA; Gul, W; Murphy, TP	1
Hua, YJ; Ma, XQ; Tian, B; Wang, GL	1
El-Gerzawy, SM; Esmat, AY; Rafaat, A	1
Li, F; Li, J; Wang, H; Wang, T; Yang, X	1
Bi, S; Kan, Y; Song, D; Tian, Y; Xu, D; Zhang, H; Zhou, X	1
Esmat, AY; Rio, MC; Tomasetto, C	1
Cao, X; Dong, Y; Huang, D; Zhao, H	1
Hu, ZH; Liao, HM; Shen, ZG; Sheng, XY	1
Boudreau, MD; Fu, PP; Xia, Q; Yin, JJ	1
Li, Q; Li, X; Pronin, AN; Tang, H; Xu, H; Zhang, L	1
Adzić, M; Nićiforović, A; Radojcić, MB; Spasić, SD	1
Bergamante, V; Ceschel, GC; Fini, A; Marazzita, S; Ronchi, C	1
Buenz, EJ	1
STONE, KG	1
Doi, Y; Hashimoto, N; Hosokawa, K; Imaida, K; Kuno, T; Matsuda, Y; Nabae, K; Saoo, K; Suzuki, S; Yamakawa, K; Yokohira, M	1
Kwon, HJ; Park, MY; Sung, MK	2
Caneva, E; Krpetić, Z; Porta, F; Scarì, G; Speranza, G	1
Ji, Y; Jia, J	1
Gopi, S; Kumar, S; Matharasi, DP; Narasimhan, S; Sivakumar, S	1
Bambagiotti-Alberti, M; Bartolucci, G; Coran, SA	1
PADILHA GONCALVES, A	1
GARDNER, JH	1
Guo, Y; Ji, R; Jiang, X; Lü, X; Wan, YF	1
Das, PK; Gantait, S; Mandal, N	1
Beninati, S; Facchiano, F; Lentini, A; Provenzano, B; Rossi, S; Tabolacci, C; Turcano, L	1
Li, G; Song, W; Wang, J; Xiao, X	1
Gulati, A; Gupta, M; Kiran, S; Singh, B; Tewari, R	1
Fani, M; Kohanteb, J	1
Ali, SA; Choudhary, RK; Galgut, JM	1
Bishayee, A; Harlev, E; Lansky, EP; Nevo, E; Ofir, R	1
Chobert, JM; Farivar, F; Ghaffari, SM; Ghamari, F; Haertlé, T; Johari, A; Moosavi-Movahedi, AA; Moosavi-Movahedi, F; Saboury, AA; Salami, M	1
Jackson, TC; Kochanek, PM; Verrier, JD	1
Castillo, S; Guillén, F; Martínez-Romero, D; Pérez-Aguilar, H; Serrano, M; Valero, D; Zapata, PJ	1
de Moraes, ML; Ferreira, M; Xavier, AC	1
Hamiza, OO; Khan, AQ; Khan, R; Lateef, A; Rehman, MU; Sultana, S; Tahir, M	1
Alpha Raj, M; Chaitanya Kumar, TV; Muralidhar, Y; Prasad, PE; Prasad, TN	1
Asres, K; Bisrat, D; Terefe, G; Tewabe, Y	1
Cui, Y; Li, Y; Qian, H; Wang, H; Xia, X; Yao, W; Ye, Q	1
Athayde, ML; Boligon, AA; Ferreira, J; Hoffmeister, C; Klafke, JZ; Oliveira, SM; Rossato, MF; Silva, CR; Silva, MA; Trevisan, G; Walker, CI	1
Cao, YY; Huan, N; Qian, H; Wang, HY; Xie, YF; Yao, WR; Zhong, Y	1
Esmat, AY; Khalil, SA; Said, MM	1
Avellone, G; Campisi, G; De Caro, V; Di Fede, O; Di Prima, G; Giannola, LI; Scaturro, AL; Sutera, FM	1
Liu, FC; Liu, FW; Tsai, HI; Wang, YR; Yu, HP	1
Chang, R; Li, Y; Qi, X; Sun, T; Wang, J; Wu, F; Yang, W; Yu, J; Zhang, W; Zhou, R	1
Andersen, K; Foderà, V; Jäger, AK; Jorgensen, L; Lobbens, ES; Nyberg, NT; van de Weert, M	1
Chung, HY; Chung, J; Heo, JY; Kim, S; Na, HS; Song, YR	1
Madhyastha, H; Madhyastha, R; Maruyama, M; Nakajima, Y; Pengjam, Y; Yamaguchi, Y	1
Fei, B; Gao, C; He, L; Hu, H; Lai, C; Lee, KI; Wang, W; Wang, X; Wang, Y; Xin, JH	1
Campas-Baypoli, ON; Cantú-Soto, EU; Cruz-Flores, P; López-Cervantes, J; Mariscal-Domínguez, MF; Sanches-Silva, A; Sánchez-Machado, DI	1
Babajanian, S; Chang, P; Gao, Q; Ingle, P; Kline, D; Ritruthai, V; Swanson, G	1
Beland, FA; Boudreau, MD; Bryant, MS; Felton, RP; Olson, GR; Tryndyak, VP	1
Choopani, R; Hajimehdipoor, H; Hamzeloo-Moghadam, M; Moein, E; Toliyat, T	1
Fan, K; Wan, L; Wang, J; Zhang, L	1
Mittal, AK; Mittal, S; Nigam, AK; Srivastava, A	1
Fan, P; Luo, X; Shi, M; Wei, X; Xie, W; Xu, N; Zhang, H; Zhang, Y	1
Ma, Y; Qi, Z; Sheng, L; Tang, T; Tao, H; Wang, Z; Zhang, Q; Zhang, Y	1
Madhyastha, H; Madhyastha, R; Maruyama, M; Nakajima, Y; Nurrahmah, QI; Pengjam, Y	1
Bai, XL; Hu, YD; Liao, X; Liu, YM; Xiao, MW; Yang, L	1
Chen, Z; Chu, J; Huang, S; Jing, K; Kong, J; Li, P; Lv, G; Quan, J; Wei, B; Wei, J	1
Jiang, Q; Li, J; Ma, Y; Qi, S; Qi, Z; Tang, T; Tao, H; Wang, Z; Zhang, Q	1
Jung, E; Kim, J	1
Chun, S; Gansukh, E; Gopal, J; Kim, DH; Muthu, M; Oh, JW; Paul, D	1
Reyes-Garcia, JG	1
García-García, E; Kaufer-Horwitz, M; Rodríguez-Flores, M	1
Bae, JS; Kim, KM; Ku, SK; Lee, C; Lee, W; Park, EK; Yang, S	1
Chen, L; Ma, F; Shen, C; Tang, Q; Wang, F; Wang, Z; Zheng, Y; Zhong, J; Zhu, J; Zhu, T	1
Baronchelli, F; Froldi, G; Grison, M; Marin, E	1
Bae, JS; Baek, MC; Jeong, GS; Ku, SK; Lee, W	1
Dai, C; Li, W; Peng, C; Shen, X; Yan, L; Yao, M; Yuan, Y; Zhang, W	1
Al-Dosari, MS; Alajmi, MF; Alam, P; Alqahtani, AS; Parvez, MK; Rehman, M	1
Çiçek, SS; Girreser, U; Ugolini, T	1
Chang, CS; Chen, TA; Chen, TC; Dutta, A; He, YC; Hseih, YC; Huang, CT; Huang, YL; Hung, CY; Lin, CY; Lin, YC; Shih, SR; Velu, AB	1
Bao, S; Chen, G; Chen, R; Cui, X; Niu, C; Sun, J; Xiao, S; Ye, W	1
Ma, C; Miao, W; Sun, R; Zhai, R	1
Cho, CW; Cho, IS; Kim, JH; Kim, KT; Lee, JI; Vinh, LB	1
Bae, JS; Lee, IC	3
Cai, T; Qi, S; Qi, Z; Tang, T; Tao, H; Wang, S; Wang, Z; Zhang, Q	1
Chen, H; Ding, J; Geng, Z; Jing, Y; Tian, HL; Wang, W; Yang, DX; Yuan, F	1
Li, Y; Peng, C; Shen, X; Yao, M; Yuan, Y; Zhang, W	1
Di, Z; Lei, J; Li, G; Li, Y; Shen, Y; Xv, G	1
Ebrahimzadeh, H; Mehrani, Z; Moradi, E	1
Gerogianni, M; Kanakis, CD; Kaparakou, EH; Maniati, M; Skotti, E; Tarantilis, PA; Vekrellis, K	1
Belemkar, S; Birari, L; Goyal, SN; Mahajan, UB; Ojha, S; Patil, CR; Patil, KR; Unger, B; Wagh, S	1
Bsoul, N; Chen, J; Chen, Z; Gao, W; Hu, X; Jiang, R; Li, B; Shao, Z; Xu, C; Zhang, C	1
Dong, H; Wang, H; Zhang, X	1
Fan, Y; Jia, H; Liang, Y; Loor, JJ; Lv, H; Sun, X; Xu, C; Xu, Q	1
Huang, W; Sun, M; Sun, W; Wang, Y; Wang, Z	1
Ayeni, EA; Chang, Q; Hu, YK; Liao, X; Ma, C; Wan, H; Yuan, H	1
Cheng, Y; Cui, Y; Guo, Y; Hu, B; Hua, H; Qian, H; Sheng, J; Zhang, W	1
Kulhari, U; Kumar, A; Kundu, S; Mugale, MN; Murty, US; Ram, C; Sahu, BD; Syed, AM	1
Cai, T; Chen, X; Cheng, J; Cheng, Z; Qi, S; Qi, Z; Wu, X	1
Clemens, RA; Hayes, AW; Pressman, P	1
Abdel-Moniem, MM; Esmat, AY; Hassan, AM; Said, MM	1
Chen, S; Chen, Y; Su, J; Xiao, J	1
Chavada, K; Ebert, MCCJC; Evoli, S; Ho, J; Kawall, A; Lewis, DSM; Mody, V; Rayalam, S; Sharma, A; Singh, A; Taval, S; Wills, S	1
Dangi, RS; Karalia, S; Kumar, V; Meena, VK; Sundd, M	1
Gao, J; Pan, J; Xie, G; Yang, S; Zhu, F	1
Fang, YX; Jiang, H; Liu, YQ; Shi, GF; Wang, Q; Yin, ZQ; Zhang, DJ; Zhang, J; Zheng, X	1
Ao, H; Chen, L; Liu, D; Peng, C; Tang, F; Wan, Y; Wu, JJ; Xia, J; Xu, JF; Yang, Y; Zhang, L	1
Chen, TT; Kong, XY; Yu, M; Zou, ZM	1
Ishii, Y; Takino, Y; Tanizawa, H	1
Akao, T; Che, QM; Hattori, M; Kobashi, K; Namba, T	1
Kan, K; Saito, K; Shindo, T; Takano, I; Uehara, S; Ushiyama, H; Yasuda, K	1
Alves, DS; Estepa, A; Micol, V; Pérez-Fons, L	1
Beppu, H; Chihara, T; Kaneko, T; Kuzuya, H; Ozaki, S; Shimpo, K; Sonoda, S; Tamai, I; Yamaji, S	1

Reviews

3 review(s) available for emodin and alloin

Article	Year
Anticancer potential of aloes: antioxidant, antiproliferative, and immunostimulatory attributes. Planta medica, 2012, Volume: 78, Issue:9 Topics: Adjuvants, Immunologic; Aloe; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Antioxidants; Emodin; Humans; Mannans; Medicine, Traditional; Plant Extracts; Plant Lectins; Plants, Medicinal	2012
The potential health benefits of aloin from genus Aloe. Phytotherapy research : PTR, 2022, Volume: 36, Issue:2 Topics: Aloe; Emodin; Plant Leaves; Plants, Medicinal	2022
Can aloin develop to medicines or healthcare products? Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153 Topics: Aloe; Anthraquinones; Anti-Inflammatory Agents; Antiviral Agents; Delivery of Health Care; Emodin; Laxatives	2022

Other Studies

138 other study(ies) available for emodin and alloin

Article	Year
High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors. Journal of medicinal chemistry, 2009, Jun-25, Volume: 52, Issue:12 Topics: Anthraquinones; Binding, Competitive; Humans; Molecular Structure; Purinergic P2 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stereoisomerism; Structure-Activity Relationship	2009
Effect of indomethacin on aloin and 1,8 dioxianthraquinone-induced production of prostaglandins in rat isolated colon. Prostaglandins, 1983, Volume: 26, Issue:4 Topics: Administration, Oral; Animals; Anthraquinones; Cathartics; Colon; Drug Interactions; Emodin; Indomethacin; Prostaglandins; Rats	1983
Sennosides and aloin do not promote dimethylhydrazine-induced colorectal tumors in mice. Pharmacology, 1993, Volume: 47 Suppl 1 Topics: 1,2-Dimethylhydrazine; Adenoma; Aloe; Animals; Anthraquinones; Carcinogens; Carcinoma; Cathartics; Colorectal Neoplasms; Dimethylhydrazines; Emodin; Incidence; Male; Mice; Plants, Medicinal; Random Allocation; Senna Extract; Sennosides	1993
A rapid high-performance thin-layer chromatographic urine screen for laxative abuse. Clinical biochemistry, 1993, Volume: 26, Issue:3 Topics: Anthraquinones; Bisacodyl; Cathartics; Chromatography, High Pressure Liquid; Emodin; Female; Humans; Male; Middle Aged; Phenolphthalein; Phenolphthaleins; Substance-Related Disorders	1993
High-performance liquid chromatographic profiles of aloe constituents and determination of aloin in beverages, with reference to the EEC regulation for flavouring substances. Journal of chromatography. A, 1995, Dec-01, Volume: 718, Issue:1 Topics: Alcoholic Beverages; Aloe; Chromatography, High Pressure Liquid; Chromones; Emodin; European Union; Flavoring Agents; Glucosides; Kinetics; Molecular Structure; Plants, Medicinal; Spectrophotometry	1995
Metabolism of aloin--the influence of nutrition. Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:8-10 Topics: Cathartics; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Emodin; Feces; Ferrous Compounds; Humans; Nutritional Physiological Phenomena	1996
Acceleration of the alcohol oxidation rate in rats with aloin, a quinone derivative of Aloe. Biochemical pharmacology, 1996, Nov-08, Volume: 52, Issue:9 Topics: Alanine Transaminase; Alcoholic Intoxication; Aloe; Animals; Anthraquinones; Aspartate Aminotransferases; Emodin; Ethanol; Female; Kinetics; Liver; Metabolic Clearance Rate; Oxidation-Reduction; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Triglycerides	1996
Effects of aloin and some structure-related anthracene, anthracenone, and anthraquinone derivatives on lipid peroxidation in rat brain cortex homogenates. Die Pharmazie, 1997, Volume: 52, Issue:5 Topics: Animals; Anthracenes; Anthraquinones; Antioxidants; Ascorbic Acid; Cerebral Cortex; Emodin; Free Radical Scavengers; Lipid Peroxidation; Rats; Thiobarbituric Acid Reactive Substances	1997
Serum LDH and ALP isozyme activities in mice bearing solid Ehrlich carcinoma and/or treated with the maximum tolerated dose (MTD) of aloin. Disease markers, 1997, Volume: 13, Issue:3 Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Emodin; Female; Isoenzymes; L-Lactate Dehydrogenase; Mice	1997
Aloe exudate: characterization by reversed phase HPLC and headspace GC-MS. Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:10 Topics: Alcoholic Beverages; Aloe; Chromatography, High Pressure Liquid; Chromones; Emodin; Gas Chromatography-Mass Spectrometry; Glucosides; Plant Leaves; Volatilization	2001
Hypotensive effect of chemical constituents from Aloe barbadensis. Planta medica, 2001, Volume: 67, Issue:8 Topics: Aloe; Animals; Anthraquinones; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Emodin; Glucosides; Hypertension; Magnetic Resonance Spectroscopy; Phytotherapy; Plant Leaves; Plant Preparations; Plant Roots; Rats	2001
Inhibition of collagenase and metalloproteinases by aloins and aloe gel. Life sciences, 2003, Jan-03, Volume: 72, Issue:7 Topics: Aloe; Aminopeptidases; Clostridium; Dose-Response Relationship, Drug; Emodin; Enzyme Inhibitors; Gels; Granulocytes; Humans; Matrix Metalloproteinase Inhibitors	2003
In vitro studies on the photobiological properties of aloe emodin and aloin A. Free radical biology & medicine, 2003, Jan-15, Volume: 34, Issue:2 Topics: Animals; Anthraquinones; Cattle; Cells, Cultured; Dermatitis, Phototoxic; DNA; DNA Damage; Emodin; Fibroblasts; Humans; Light; Oxidative Stress; Photosensitivity Disorders; Ultraviolet Rays	2003
[Determination of the active components in Chinese herb Aloe vera L. var. chinensis (Haw.) Berger by capillary zone electrophoresis]. Se pu = Chinese journal of chromatography, 2000, Volume: 18, Issue:5 Topics: Aloe; Anthraquinones; Electrophoresis, Capillary; Emodin	2000
Aloin, cinnamic acid and sophorcarpidine are potent inhibitors of tyrosinase. Chinese medical journal, 2002, Volume: 115, Issue:12 Topics: Cinnamates; Cosmetics; Emodin; Enzyme Inhibitors; Humans; Hyperpigmentation; Monophenol Monooxygenase; Plant Preparations	2002
A paper chromatographic study of aloe, aloin and of cascara sagrada. Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1956, Volume: 45, Issue:4 Topics: Aloe; Chromatography, Paper; Emodin; Humans; Rhamnus	1956
[Studies on the aloin of the cape aloe]. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1955, Volume: 288, Issue:11-12 Topics: Aloe; Emodin; Humans	1955
[Assay of aloe; photometric determination of aloin]. Annales pharmaceutiques francaises, 1956, Volume: 14, Issue:12 Topics: Aloe; Biological Assay; Cathartics; Emodin; Humans	1956
[Quantitative determination of aloin in Aloe capensis. I. Determination by paper chromatography with planimetric evaluation of spot surfaces]. Die Pharmazie, 1957, Volume: 12, Issue:10 Topics: Aloe; Cathartics; Chromatography, Paper; Emodin	1957
Vegetable purgatives containing anthracene derivatives. IX. An aloin-like substance in Rhamnus purshiana DC. The Journal of pharmacy and pharmacology, 1958, Volume: 10, Issue:Supp Topics: Anthracenes; Cathartics; Emodin; Rhamnus; Vegetables	1958
The chromatographic behaviour of aloin. The Journal of pharmacy and pharmacology, 1959, Volume: 11, Issue:6 Topics: Emodin; Glycosides; Humans	1959
[On the constituents of the bark of Rhamnus purshiana (Cascara Sagrada Ph. Helv. V). 1. Assay for the presence of xanthorhamnin and the detection of aloin]. Pharmaceutica acta Helvetiae, 1961, Volume: 36 Topics: Biological Assay; Catecholamines; Emodin; Flavones; Glycosides; Health Services; Rhamnus	1961
Vegetable purgatives containing anthracene derivatives. XI. Further work on the aloin-like substance of Rhamnus purshiana DC. The Journal of pharmacy and pharmacology, 1960, Volume: 12(Suppl) Topics: Anthracenes; Anthraquinones; Catecholamines; Cathartics; Emodin; Rhamnus; Vegetables	1960
[Aloin, some observations on its constitution]. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1960, Volume: 293/65 Topics: Anthracenes; Emodin	1960
[Microanalytical determination of aloin]. Pharmaceutisch weekblad, 1962, Oct-12, Volume: 97 Topics: Aloe; Chemistry Techniques, Analytical; Emodin	1962
[On the occurrence of aloin in Aloe vera in addition to comparative studies with the fresh juice of Capealoe (Aloe ferox) and the dried extract prepared from it]. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1962, Volume: 295/67 Topics: Aloe; Anthraquinones; Emodin; Humans	1962
CHEMOTAXONOMY OF ASPHODELIODEAE (LILIACEAE) KRAUSE 1930. VI. ALOIN AND HOMONATALOIN IN ALOE SPECIES. Die Naturwissenschaften, 1965, Volume: 52 Topics: Aloe; Chemical Phenomena; Chemistry; Emodin; Liliaceae; Research	1965
MICRO-DETERMINATION OF ALOIN IN SOME SOUTH AFRICAN ALOE SPECIES. Pharmaceutisch weekblad, 1965, Jun-18, Volume: 100 Topics: Alkaloids; Aloe; Chemistry, Pharmaceutical; Emodin; Microchemistry; Pharmacy; Research; South Africa	1965
[A method for the quantitative determination of aloin]. Arzneimittel-Forschung, 1962, Volume: 12 Topics: Aloe; Emodin; Photometry	1962
Radical-scavenging effects of Aloe arborescens Miller on prevention of pancreatic islet B-cell destruction in rats. Journal of ethnopharmacology, 2003, Volume: 89, Issue:1 Topics: Alloxan; Aloe; Animals; Antioxidants; Cells, Cultured; Chromatography, High Pressure Liquid; Emodin; Free Radical Scavengers; Islets of Langerhans; Plant Extracts; Plant Leaves; Plant Preparations; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin	2003
[Development of aloin cells and accumulation of anthraquinone in aloe leaf]. Shi yan sheng wu xue bao, 2003, Volume: 36, Issue:5 Topics: Aloe; Anthraquinones; Emodin; Plant Leaves; Plants, Medicinal	2003
[Determination of aloin in aloes by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:4 Topics: Aloe; Chromatography, High Pressure Liquid; Emodin; Plants, Medicinal	2003
Analysis of the anthraquinones aloe-emodin and aloin by gas chromatography/mass spectrometry. International immunopharmacology, 2004, Dec-20, Volume: 4, Issue:14 Topics: Aloe; Anthraquinones; Emodin; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Reference Standards; Reproducibility of Results	2004
[Relationship between antibacterial activity of aloe and its anthaquinone compounds]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:11 Topics: Aloe; Anthraquinones; Anti-Bacterial Agents; Bacillus subtilis; Drugs, Chinese Herbal; Emodin; Escherichia coli; Plant Leaves; Plants, Medicinal; Proteus vulgaris; Pseudomonas aeruginosa; Staphylococcus aureus	2003
DNA ploidy and S phase fraction of breast and ovarian tumor cells treated with a natural anthracycline analog (aloin). Cancer biology & therapy, 2005, Volume: 4, Issue:1 Topics: Aloe; Breast Neoplasms; DNA; Emodin; Female; Humans; Ovarian Neoplasms; Ploidies; S Phase; Tumor Cells, Cultured	2005
[Determination of aloin content in callus of Aloe vera var. chinensis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2004, Volume: 27, Issue:9 Topics: Aloe; China; Chromatography, High Pressure Liquid; Culture Media; Drugs, Chinese Herbal; Emodin; Plant Growth Regulators; Plant Leaves; Plant Roots; Plant Stems; Plants, Medicinal; Tissue Culture Techniques	2004
Spectroscopic characterization of effective components anthraquinones in Chinese medicinal herbs binding with serum albumins. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 62, Issue:1-3 Topics: Anthraquinones; Binding Sites; Drugs, Chinese Herbal; Emodin; Humans; Models, Molecular; Molecular Structure; Serum Albumin; Serum Albumin, Bovine	2005
Cytotoxicity of a natural anthraquinone (Aloin) against human breast cancer cell lines with and without ErbB-2: topoisomerase IIalpha coamplification. Cancer biology & therapy, 2006, Volume: 5, Issue:1 Topics: Antigens, Neoplasm; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cyclin B; DNA Topoisomerases, Type II; DNA-Binding Proteins; Down-Regulation; Drug Resistance, Neoplasm; Emodin; Flow Cytometry; Gene Amplification; Humans; Mitosis; Receptor, ErbB-2	2006
[Preparative separation of aloin diastereoisomers by high-speed countercurrent chromatography combined with silica gel column chromatography]. Se pu = Chinese journal of chromatography, 2006, Volume: 24, Issue:1 Topics: Aloe; Anti-Bacterial Agents; Countercurrent Distribution; Drugs, Chinese Herbal; Emodin; Reference Standards; Silica Gel; Silicates; Silicon Dioxide; Spectrometry, Mass, Fast Atom Bombardment	2006
[Ultracytochemical studies of aloin in Aloe arborescens leaves]. Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology, 2006, Volume: 39, Issue:1 Topics: Aloe; Emodin; Microscopy, Electron, Transmission; Plant Leaves	2006
Photo-irradiation of Aloe vera by UVA--formation of free radicals, singlet oxygen, superoxide, and induction of lipid peroxidation. Toxicology letters, 2007, Jan-30, Volume: 168, Issue:2 Topics: Aloe; Electron Spin Resonance Spectroscopy; Emodin; Free Radical Scavengers; Free Radicals; Linoleic Acids; Lipid Peroxidation; Plant Extracts; Reactive Oxygen Species; Superoxides; Ultraviolet Rays	2007
Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin. Current biology : CB, 2007, Aug-21, Volume: 17, Issue:16 Topics: Emodin; Humans; Phenylthiourea; Polymorphism, Single Nucleotide; Receptors, G-Protein-Coupled; Saccharin; Taste	2007
Antitumor effects of a natural anthracycline analog (Aloin) involve altered activity of antioxidant enzymes in HeLaS3 cells. Cancer biology & therapy, 2007, Volume: 6, Issue:8 Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Cycle; Cell Proliferation; Emodin; Female; HeLa Cells; Humans; NF-kappa B; Oxidoreductases; Uterine Cervical Neoplasms	2007
Effect of vehicles on topical application of aloe vera and arnica montana components. Drug delivery, 2007, Volume: 14, Issue:7 Topics: Administration, Cutaneous; Aloe; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arnica; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Diffusion; Emodin; Emulsions; Excipients; Gels; Humans; Permeability; Pharmaceutical Vehicles; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Guaiane; Skin Absorption; Swine	2007
Aloin induces apoptosis in Jurkat cells. Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:2 Topics: Aloe; Anthraquinones; Apoptosis; Cell Cycle; Cell Death; Cell Division; Chromatography, High Pressure Liquid; Cytoplasmic Granules; Dietary Supplements; Emodin; Humans; Jurkat Cells; Mass Spectrometry; Mitochondrial Membranes	2008
The estimation of aloin in pharmaceuticals. Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1947, Volume: 36, Issue:12 Topics: Emodin; Humans	1947
Equivocal colonic carcinogenicity of Aloe arborescens Miller var. natalensis berger at high-dose level in a Wistar Hannover rat 2-y study. Journal of food science, 2009, Volume: 74, Issue:2 Topics: Aloe; Animals; Colonic Neoplasms; Diarrhea; Disease Models, Animal; Emodin; Female; Glucosides; Male; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Survival Rate	2009
Evaluation of aloin and aloe-emodin as anti-inflammatory agents in aloe by using murine macrophages. Bioscience, biotechnology, and biochemistry, 2009, Apr-23, Volume: 73, Issue:4 Topics: Aloe; Animals; Anthraquinones; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Emodin; Flavonols; Gene Expression Regulation, Enzymologic; Isoflavones; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; RNA, Messenger	2009
Gold nanoparticles prepared using cape aloe active components. Langmuir : the ACS journal of surfaces and colloids, 2009, Jul-07, Volume: 25, Issue:13 Topics: Chromones; Emodin; Glucosides; Gold; HeLa Cells; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Molecular Structure; Plant Extracts; Transport Vesicles	2009
Ultraviolet light absorption of an ophthalmic formulation with Aloe extracts. Natural product communications, 2009, Volume: 4, Issue:9 Topics: Aloe; Emodin; Lactones; Ophthalmic Solutions; Plant Leaves; Polysaccharides; Sesquiterpenes; Spectrophotometry, Ultraviolet; Ultraviolet Rays	2009
Synthesis of cytotoxic and antioxidant Schiff's base analogs of aloin. Journal of Asian natural products research, 2010, Volume: 12, Issue:5 Topics: Aloe; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Artemia; Biphenyl Compounds; Combinatorial Chemistry Techniques; Emodin; Molecular Structure; Picrates; Plants, Medicinal; Schiff Bases	2010
Selective determination of aloin in different matrices by HPTLC densitometry in fluorescence mode. Journal of pharmaceutical and biomedical analysis, 2011, Jan-25, Volume: 54, Issue:2 Topics: Boric Acids; Calibration; Chromatography, Thin Layer; Densitometry; Emodin; High-Throughput Screening Assays; Molecular Structure; Reference Standards; Reproducibility of Results; Solutions; Spectrometry, Fluorescence; Time Factors	2011
Professional contact dermatitis; positive contact test for podophyllin and aloin (with the presence of the patient). Anais brasileiros de dermatologia e sifilografia, 1945, Volume: 20 Topics: Dermatitis, Contact; Emodin; Humans; Hypersensitivity; Industry; Occupations; Podophyllin	1945
A comparison between certain reactions of the aloins and those of glucose. Journal of the American Chemical Society, 1945, Volume: 67 Topics: Emodin; Glucose	1945
Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model. Life sciences, 2011, Mar-14, Volume: 88, Issue:11-12 Topics: Aloe; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromones; Colitis; Colon; Diet; Dietary Supplements; Disease Models, Animal; Emodin; Gels; Glucosides; Interleukin-1beta; Leukotriene B4; Male; Peroxidase; Plant Preparations; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	2011
[The protective effects of sodium selenite and aloin against ultraviolet A radiation]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2011, Volume: 42, Issue:1 Topics: Adolescent; Cells, Cultured; Dermis; Emodin; Fibroblasts; Humans; Male; Radiation-Protective Agents; Skin Aging; Sodium Selenite; Ultraviolet Rays; Young Adult	2011
In vitro accelerated mass propagation and ex vitro evaluation of Aloe vera L. with aloin content and superoxide dismutase activity. Natural product research, 2011, Volume: 25, Issue:14 Topics: Aloe; Benzyl Compounds; Emodin; Indoleacetic Acids; Naphthaleneacetic Acids; Plant Roots; Plant Shoots; Purines; Superoxide Dismutase	2011
Aloin enhances cisplatin antineoplastic activity in B16-F10 melanoma cells by transglutaminase-induced differentiation. Amino acids, 2013, Volume: 44, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Drug Synergism; Emodin; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Spermine; Transglutaminases	2013
Microwave-assisted extraction performed in low temperature and in vacuo for the extraction of labile compounds in food samples. Analytica chimica acta, 2012, Jan-27, Volume: 712 Topics: Ascorbic Acid; beta Carotene; Chromatography, High Pressure Liquid; Cold Temperature; Emodin; Food Analysis; Kinetics; Microwaves; Xanthophylls	2012
Isolation and identification of phosphate solubilizing bacteria able to enhance the growth and aloin-A biosynthesis of Aloe barbadensis Miller. Microbiological research, 2012, Jun-20, Volume: 167, Issue:6 Topics: Aloe; Bacteria; DNA, Bacterial; DNA, Ribosomal; Emodin; Phosphates; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Soil; Soil Microbiology	2012
Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria. Journal of oral science, 2012, Volume: 54, Issue:1 Topics: Aggregatibacter actinomycetemcomitans; Aloe; Bacteroides; Colony Count, Microbial; Dental Caries; Emodin; Gels; Humans; Microbial Sensitivity Tests; Periodontal Diseases; Plant Extracts; Plant Leaves; Porphyromonas gingivalis; Streptococcus mutans	2012
On the novel action of melanolysis by a leaf extract of Aloe vera and its active ingredient aloin, potent skin depigmenting agents. Planta medica, 2012, Volume: 78, Issue:8 Topics: Aloe; Animals; Bufonidae; Cells, Cultured; Emodin; Hyperpigmentation; Melanophores; Pigmentation; Plant Extracts	2012
Synergic study of α-glucosidase inhibitory action of aloin and its antioxidant activity with and without camel β-casein and its peptides. Protein and peptide letters, 2013, Volume: 20, Issue:5 Topics: Aloe; alpha-Glucosidases; Animals; Antioxidants; Camelus; Caseins; Emodin; Glycoside Hydrolase Inhibitors; Hydrolysis; Linear Models; Milk; Peptides	2013
Anthraquinone-2-sulfonic acid (AQ2S) is a novel neurotherapeutic agent. Cell death & disease, 2013, Jan-10, Volume: 4 Topics: Animals; Anthraquinones; Apoptosis; Caspases; Cell Survival; Cells, Cultured; Chromones; Emodin; Hydrogen Peroxide; Lipid Peroxidation; Morpholines; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Staurosporine	2013
Is it possible to increase the aloin content of Aloe vera by the use of ultraviolet light? Journal of agricultural and food chemistry, 2013, Mar-06, Volume: 61, Issue:9 Topics: Aloe; Botrytis; Chlorophyll; Emodin; Fungicides, Industrial; Penicillium; Plant Leaves; Ultraviolet Rays	2013
Immobilization of aloin encapsulated into liposomes in layer-by-layer films for transdermal drug delivery. Materials science & engineering. C, Materials for biological applications, 2013, Apr-01, Volume: 33, Issue:3 Topics: Absorption; Administration, Cutaneous; Chemistry, Pharmaceutical; Drug Delivery Systems; Emodin; Liposomes; Phosphatidylglycerols; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet	2013
Chemopreventive effects of aloin against 1,2-dimethylhydrazine-induced preneoplastic lesions in the colon of Wistar rats. Human & experimental toxicology, 2014, Volume: 33, Issue:2 Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Colonic Diseases; Emodin; Gene Expression Regulation, Enzymologic; Male; Precancerous Conditions; Rats; Rats, Wistar	2014
Evaluation of therapeutic potential of nanosilver particles synthesised using aloin in experimental murine mastitis model. IET nanobiotechnology, 2013, Volume: 7, Issue:3 Topics: Animals; Antioxidants; Body Weight; Disease Models, Animal; Drug Design; Emodin; Female; Mastitis; Metal Nanoparticles; Mice; Phylogeny; Silver; Staphylococcal Infections	2013
Antitrypanosomal activity of aloin and its derivatives against Trypanosoma congolense field isolate. BMC veterinary research, 2014, Mar-10, Volume: 10 Topics: Animals; Anthraquinones; Diminazene; Dose-Response Relationship, Drug; Emodin; Female; Mice; Molecular Structure; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African	2014
Aloin protects against chronic alcoholic liver injury via attenuating lipid accumulation, oxidative stress and inflammation in mice. Archives of pharmacal research, 2014, Volume: 37, Issue:12 Topics: Animals; Antioxidants; Biomarkers; Cytokines; Disease Models, Animal; Emodin; Hepatitis, Alcoholic; Lipid Metabolism; Lipid Peroxidation; Liver Function Tests; Male; Mice, Inbred Strains; Oxidative Stress	2014
Anti-inflammatory and antioxidant effects of Aloe saponaria Haw in a model of UVB-induced paw sunburn in rats. Journal of photochemistry and photobiology. B, Biology, 2014, Apr-05, Volume: 133 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Chromatography, High Pressure Liquid; Disease Models, Animal; Emodin; Inflammation; Male; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Saponaria; Silver Sulfadiazine; Skin; Sunburn; Time Factors; Ultraviolet Rays	2014
[Structural characterization and spectroscopic analysis of the aloin]. Guang pu xue yu guang pu fen xi = Guang pu, 2014, Volume: 34, Issue:2 Topics: Emodin; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Vibration	2014
Aloin: a natural antitumor anthraquinone glycoside with iron chelating and non-atherogenic activities. Pharmaceutical biology, 2015, Volume: 53, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Cardiotoxicity; Doxorubicin; Emodin; Glycosides; Heart; Iron; Iron Chelating Agents; Kidney; Kidney Function Tests; Lipids; Male; Organ Size; Rats; Spleen	2015
Aloin delivery on buccal mucosa: ex vivo studies and design of a new locoregional dosing system. Drug development and industrial pharmacy, 2015, Volume: 41, Issue:9 Topics: Acrylic Resins; Adhesiveness; Aloe; Animals; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Liberation; Emodin; Mouth Mucosa; Permeability; Polymers; Reproducibility of Results; Swine; Tablets	2015
Aloin Protects Skin Fibroblasts from Heat Stress-Induced Oxidative Stress Damage by Regulating the Oxidative Defense System. PloS one, 2015, Volume: 10, Issue:12 Topics: 8-Hydroxy-2'-Deoxyguanosine; Cell Line; Cell Proliferation; Cell Survival; Deoxyguanosine; Emodin; Fibroblasts; Gene Expression Regulation; Glutathione; Hot Temperature; Humans; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Skin; Superoxide Dismutase	2015
Protective effects of aloin on oxygen and glucose deprivation-induced injury in PC12 cells. Brain research bulletin, 2016, Volume: 121 Topics: Animals; bcl-2-Associated X Protein; Calcium; Caspase 3; Cell Hypoxia; Dose-Response Relationship, Drug; Emodin; Flow Cytometry; Gene Expression Regulation; Glucose; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidative Stress; Oxides; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Sodium Compounds; Thiazolidinediones; Time Factors	2016
The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products--A Study Using Aloin and Insulin. PloS one, 2016, Volume: 11, Issue:2 Topics: Anthraquinones; Benzothiazoles; Biological Products; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Emodin; Excipients; Fluorescent Dyes; Glucosides; Insulin; Microscopy, Electron, Transmission; Oxidation-Reduction; Protein Stability; Proteolysis; Solutions; Spectrometry, Fluorescence; Thiazoles	2016
Aloin Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells. Journal of periodontology, 2016, Volume: 87, Issue:6 Topics: Cells, Cultured; Emodin; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; KB Cells; Mouth Diseases; p38 Mitogen-Activated Protein Kinases	2016
NF-κB pathway inhibition by anthrocyclic glycoside aloin is key event in preventing osteoclastogenesis in RAW264.7 cells. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Apr-15, Volume: 23, Issue:4 Topics: Aloe; Animals; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Emodin; Humans; I-kappa B Kinase; I-kappa B Proteins; Macrophages; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Osteoclasts; Osteoporosis; Phytotherapy; Plant Extracts; RANK Ligand; RAW 264.7 Cells	2016
Antibacterial modification of an injectable, biodegradable, non-cytotoxic block copolymer-based physical gel with body temperature-stimulated sol-gel transition and controlled drug release. Colloids and surfaces. B, Biointerfaces, 2016, Jul-01, Volume: 143 Topics: Anti-Bacterial Agents; Biodegradation, Environmental; Body Temperature; Cathartics; Cell Survival; Delayed-Action Preparations; Drug Liberation; Emodin; Epidermis; Escherichia coli; Gels; Humans; Hydrophobic and Hydrophilic Interactions; Injections; L-Lactate Dehydrogenase; Micelles; Phase Transition; Polyesters; Polyethylene Glycols; Skin, Artificial; Staphylococcus aureus; Transition Temperature	2016
An HPLC Procedure for the Quantification of Aloin in Latex and Gel from Aloe barbadensis Leaves. Journal of chromatographic science, 2017, 03-01, Volume: 55, Issue:3 Topics: Aloe; Chromatography, High Pressure Liquid; Emodin; Latex; Limit of Detection; Linear Models; Plant Extracts; Plant Leaves; Reproducibility of Results	2017
Quantitative Analysis of Aloins and Aloin-Emodin in Aloe Vera Raw Materials and Finished Products Using High-Performance Liquid Chromatography: Single-Laboratory Validation, First Action 2016.09. Journal of AOAC International, 2017, May-01, Volume: 100, Issue:3 Topics: Aloe; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Emodin	2017
From the Cover: Aloin, a Component of the Aloe Vera Plant Leaf, Induces Pathological Changes and Modulates the Composition of Microbiota in the Large Intestines of F344/N Male Rats. Toxicological sciences : an official journal of the Society of Toxicology, 2017, 08-01, Volume: 158, Issue:2 Topics: Aloe; Animals; Colon; Dose-Response Relationship, Drug; Emodin; Feces; Gastrointestinal Microbiome; Growth; Male; Plant Extracts; Plant Leaves; Rats; Rats, Inbred F344	2017
Formulation of an aloe-based product according to Iranian traditional medicine and development of its analysis method. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2017, Aug-29, Volume: 25, Issue:1 Topics: Aloe; Cinnamomum; Drug Compounding; Emodin; Flowers; Fruit; Herbal Medicine; Iran; Medicine, Traditional; Nardostachys; Phytotherapy; Piper; Pistacia; Plant Bark; Rhizome; Rosa; Tablets	2017
Aloin promotes A549 cell apoptosis via the reactive oxygen species‑mitogen activated protein kinase signaling pathway and p53 phosphorylation. Molecular medicine reports, 2017, Volume: 16, Issue:5 Topics: A549 Cells; Animals; Apoptosis; Cell Proliferation; Emodin; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mitogen-Activated Protein Kinase 1; Neoplasm Proteins; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53	2017
Role of aloin in the modulation of certain immune parameters in skin mucus of an Indian major carp, Labeo rohita. Fish & shellfish immunology, 2018, Volume: 73 Topics: Adjuvants, Immunologic; Animals; Carps; Emodin; Immunity, Innate; Injections, Intraperitoneal; Mucus; Random Allocation; Skin	2018
Aloin Suppresses Lipopolysaccharide-Induced Inflammatory Response and Apoptosis by Inhibiting the Activation of NF-κB. Molecules (Basel, Switzerland), 2018, Feb-26, Volume: 23, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Survival; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Emodin; Inflammation; Inflammation Mediators; Lipopolysaccharides; Macrophages; Mice; Models, Biological; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Protein Transport; Signal Transduction; Transcription Factor RelA	2018
Aloin suppresses lipopolysaccharide‑induced inflammation by inhibiting JAK1‑STAT1/3 activation and ROS production in RAW264.7 cells. International journal of molecular medicine, 2018, Volume: 42, Issue:4 Topics: Animals; Emodin; Inflammation; Janus Kinase 1; Lipopolysaccharides; Mice; RAW 264.7 Cells; Reactive Oxygen Species; STAT1 Transcription Factor; STAT3 Transcription Factor	2018
The pivotal role of microRNA-21 in osteoclastogenesis inhibition by anthracycline glycoside aloin. Journal of natural medicines, 2019, Volume: 73, Issue:1 Topics: Animals; Anthracyclines; Emodin; Glycosides; Humans; Mice; MicroRNAs; Osteoclasts; Osteogenesis; Transfection	2019
Rapid quantification of aloin A and B in aloe plants and aloe-containing beverages, and pharmaceutical preparations by microchip capillary electrophoresis with laser induced fluorescence detection. Journal of separation science, 2018, Volume: 41, Issue:19 Topics: Aloe; Beverages; Electrophoresis, Microchip; Emodin; Fluorescence; Lasers; Molecular Conformation; Plant Extracts; Spectrometry, Fluorescence	2018
Aloin promotes osteogenesis of bone-marrow-derived mesenchymal stem cells via the ERK1/2-dependent Runx2 signaling pathway. Journal of natural medicines, 2019, Volume: 73, Issue:1 Topics: Animals; Bone Marrow; Cell Differentiation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Emodin; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Mesenchymal Stem Cells; Osteogenesis; Rats; Rats, Sprague-Dawley; Signal Transduction	2019
[Aloin induces apoptosis Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018, Aug-30, Volume: 38, Issue:9 Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Emodin; Fluorescent Dyes; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Stomach Neoplasms	2018
Aloin Inhibits Müller Cells Swelling in a Rat Model of Thioacetamide-Induced Hepatic Retinopathy. Molecules (Basel, Switzerland), 2018, Oct-29, Volume: 23, Issue:11 Topics: Ammonia; Animals; Aquaporin 4; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Emodin; Ependymoglial Cells; Hepatic Encephalopathy; Liver; Male; Potassium Channels, Inwardly Rectifying; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Thioacetamide	2018
Ultrasound mediated accelerated Anti-influenza activity of Aloe vera. Scientific reports, 2018, 12-12, Volume: 8, Issue:1 Topics: Aloe; Animals; Anthraquinones; Antiviral Agents; Cell Line; Dogs; Emodin; Flavonoids; Madin Darby Canine Kidney Cells; Orthomyxoviridae; Phenol; Plant Extracts; Plant Leaves; Plants, Medicinal; Solvents; Ultrasonic Waves	2018
Safety of drug combinations based on psychoactive agents in the treatment of obesity (A reply by the authors). International journal of clinical pharmacology and therapeutics, 2019, Volume: 57, Issue:5 Topics: Atropine; Diazepam; Drug Combinations; Emodin; Humans; Obesity; Phenylpropanolamine; Psychotropic Drugs; Triiodothyronine	2019
Safety of drug combinations based on psychoactive agents in the treatment of obesity. International journal of clinical pharmacology and therapeutics, 2019, Volume: 57, Issue:5 Topics: Atropine; Diazepam; Drug Combinations; Emodin; Humans; Obesity; Phenylpropanolamine; Psychotropic Drugs; Triiodothyronine	2019
Aloin reduces inflammatory gene iNOS via inhibition activity and p-STAT-1 and NF-κB. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 126 Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Emodin; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Lung Diseases; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Plant Extracts; STAT1 Transcription Factor; Tumor Necrosis Factor-alpha	2019
Aloin attenuates cognitive impairment and inflammation induced by d-galactose via down-regulating ERK, p38 and NF-κB signaling pathway. International immunopharmacology, 2019, Volume: 72 Topics: Animals; Brain; Cognitive Dysfunction; Cytokines; Down-Regulation; Emodin; Galactose; Glutathione; Male; MAP Kinase Signaling System; Maze Learning; Mice, Inbred C57BL; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Superoxide Dismutase	2019
Antiglycation Activity and HT-29 Cellular Uptake of Aloe-Emodin, Aloin, and Molecules (Basel, Switzerland), 2019, Jun-05, Volume: 24, Issue:11 Topics: Aloe; Anthraquinones; Biphenyl Compounds; Cell Survival; Emodin; Flavonoids; Glycosylation; HT29 Cells; Humans; Hypoglycemic Agents; Methanol; Phenols; Phytochemicals; Picrates; Plant Extracts	2019
Renal protective effects of aloin in a mouse model of sepsis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 132 Topics: Animals; Cell Line; Emodin; I-kappa B Proteins; Interleukin-6; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Protective Agents; Sepsis; Tumor Necrosis Factor-alpha	2019
Study of the aqueous extract of Aloe vera and its two active components on the Wnt/β-catenin and Notch signaling pathways in colorectal cancer cells. Journal of ethnopharmacology, 2019, Oct-28, Volume: 243 Topics: Aloe; Animals; beta Catenin; Cell Line; Cell Proliferation; Chromones; Colorectal Neoplasms; Emodin; Glucosides; Humans; Mice; Plant Extracts; Receptors, Notch; Signal Transduction; Wnt Proteins	2019
The anti-hepatitis B virus therapeutic potential of anthraquinones derived from Aloe vera. Phytotherapy research : PTR, 2019, Volume: 33, Issue:11 Topics: Aloe; Anthraquinones; Antiviral Agents; Cell Line; Emodin; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Humans; Phytotherapy; Plant Extracts	2019
Quality control of Aloe vera (Aloe barbadensis) and Aloe ferox using band-selective quantitative heteronuclear single quantum correlation spectroscopy (bs-qHSQC). Talanta, 2019, Dec-01, Volume: 205 Topics: Aloe; Emodin; Quality Control; Spectrum Analysis	2019
Effect of aloin on viral neuraminidase and hemagglutinin-specific T cell immunity in acute influenza. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 64 Topics: Aloe; Animals; Antiviral Agents; Cell Line; Drug Resistance, Viral; Emodin; Hemagglutinins; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuraminidase; Oseltamivir; Plant Leaves; T-Lymphocytes; Viral Proteins	2019
UHPLC-MS/MS method for the quantification of aloin-A in rat plasma and its application to a pharmacokinetic study. Journal of pharmaceutical and biomedical analysis, 2020, Jan-30, Volume: 178 Topics: Administration, Oral; Animals; Anthraquinones; Biological Availability; Chromatography, High Pressure Liquid; Emodin; Male; Plant Extracts; Plasma; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry	2020
Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway. Cancer medicine, 2020, Volume: 9, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Drug Synergism; Emodin; Female; Hep G2 Cells; Humans; Liver Neoplasms; Metformin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays	2020
An investigation of the inhibitory mechanism of α-glucosidase by chysalodin from Aloe vera. International journal of biological macromolecules, 2020, Mar-15, Volume: 147 Topics: Aloe; alpha-Glucosidases; Carbon-13 Magnetic Resonance Spectroscopy; Emodin; Enzyme Assays; Fluorescence; Glycoside Hydrolase Inhibitors; Kinetics; Proton Magnetic Resonance Spectroscopy	2020
Inhibitory effects of aloin on TGFBIp-mediated septic responses. Journal of Asian natural products research, 2021, Volume: 23, Issue:2 Topics: Animals; Emodin; Extracellular Matrix Proteins; Human Umbilical Vein Endothelial Cells; Mice; Mice, Inbred C57BL; Molecular Structure; Transforming Growth Factor beta	2021
Aloin Inhibits the Proliferation and Migration of Gastric Cancer Cells by Regulating NOX2-ROS-Mediated Pro-Survival Signal Pathways. Drug design, development and therapy, 2020, Volume: 14 Topics: Cell Movement; Cell Proliferation; Emodin; Humans; NADPH Oxidase 2; Reactive Oxygen Species; Signal Transduction; Stomach Neoplasms; Survival Analysis; Tumor Cells, Cultured	2020
Suppressive effects of aloin on polyphosphate-mediated vascular inflammatory responses. Journal of Asian natural products research, 2021, Volume: 23, Issue:1 Topics: Animals; Emodin; Human Umbilical Vein Endothelial Cells; Mice; Mice, Inbred C57BL; Molecular Structure; NF-kappa B; Polyphosphates; Tumor Necrosis Factor-alpha	2021
Aloin Protects Against Blood-Brain Barrier Damage After Traumatic Brain Injury in Mice. Neuroscience bulletin, 2020, Volume: 36, Issue:6 Topics: Animals; Blood-Brain Barrier; Brain Injuries, Traumatic; Disease Models, Animal; Emodin; Endothelial Cells; Male; Mice; Mice, Inbred C57BL; Stress, Mechanical	2020
Post-transcriptional regulation activity through alternative splicing involved in the effects of Aloe vera on the Wnt/β-catenin and Notch pathways in colorectal cancer cells. Journal of pharmacological sciences, 2020, Volume: 143, Issue:3 Topics: Aloe; Alternative Splicing; beta Catenin; Carcinogenesis; Cell Line, Tumor; Chromones; Colorectal Neoplasms; Emodin; Glucosides; Humans; Plant Extracts; Receptors, Notch; RNA Processing, Post-Transcriptional; Signal Transduction; Wnt Proteins	2020
Aloin suppresses lipopolysaccharide-induced acute lung injury by inhibiting NLRP3/NF-κB via activation of SIRT1 in mice. Immunopharmacology and immunotoxicology, 2020, Volume: 42, Issue:4 Topics: Acute Lung Injury; Aloe; Animals; Dose-Response Relationship, Drug; Emodin; Female; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Neutrophils; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Sirtuin 1	2020
Use of aloin-based and rosin-based electrospun nanofibers as natural nanosorbents for the extraction of polycyclic aromatic hydrocarbons and phenoxyacetic acid herbicides by microextraction in packed syringe method prior to GC-FID detection. Mikrochimica acta, 2020, 06-22, Volume: 187, Issue:7 Topics: Adsorption; Emodin; Flame Ionization; Herbicides; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Nanofibers; Polycyclic Aromatic Hydrocarbons; Resins, Plant; Seawater; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical	2020
Quantitative determination of aloin, antioxidant activity, and toxicity of Aloe vera leaf gel products from Greece. Journal of the science of food and agriculture, 2021, Jan-30, Volume: 101, Issue:2 Topics: Aliivibrio fischeri; Aloe; Antioxidants; Cell Line; Chromatography, High Pressure Liquid; Emodin; Greece; Humans; Plant Extracts; Plant Leaves; Plant Preparations	2021
Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines. Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Cardiotoxicity; Cathartics; Cytokines; Doxorubicin; Emodin; Inflammation Mediators; Male; Oxidative Stress; Rats; Rats, Wistar	2020
Inhibition of PI3K/Akt/NF-κB signaling by Aloin for ameliorating the progression of osteoarthritis: In vitro and in vivo studies. International immunopharmacology, 2020, Volume: 89, Issue:Pt B Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Chondrocytes; Disease Models, Animal; Emodin; Extracellular Matrix; Interleukin-1beta; Joints; Male; Mice, Inbred C57BL; Molecular Docking Simulation; NF-kappa B; Osteoarthritis; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction	2020
Inhibition of NOX2 contributes to the therapeutic effect of aloin on traumatic brain injury. Folia neuropathologica, 2020, Volume: 58, Issue:3 Topics: Animals; Brain; Brain Injuries, Traumatic; Cytokines; Emodin; Insulin-Like Growth Factor I; Maze Learning; Mice; NADPH Oxidase 2; Oxidative Stress; PC12 Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase	2020
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling. Food & function, 2021, Jan-21, Volume: 12, Issue:2 Topics: Amino Acids; Animals; Apoptosis; Biomarkers; Choline Deficiency; Diet; Dietary Fats; Emodin; Gene Expression Regulation; Heme Oxygenase-1; Inflammation; Liver; Male; Membrane Proteins; Mice; Mice, Knockout; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease	2021
Aloin antagonizes stimulated ischemia/reperfusion-induced damage and inflammatory response in cardiomyocytes by activating the Nrf2/HO-1 defense pathway. Cell and tissue research, 2021, Volume: 384, Issue:3 Topics: Animals; Cell Line; Emodin; Heme Oxygenase-1; Inflammation; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Rats; Reperfusion Injury	2021
Fishing of α-Glucosidase's Ligands from Molecules (Basel, Switzerland), 2021, Sep-26, Volume: 26, Issue:19 Topics: Aloe; alpha-Glucosidases; Cathartics; Emodin; Enzymes, Immobilized; Glucosides; Ligands; Magnetite Nanoparticles; Plant Extracts	2021
The Intervention and Mechanism of Action for Aloin against Subchronic Aflatoxin B1 Induced Hepatic Injury in Rats. International journal of molecular sciences, 2021, Oct-27, Volume: 22, Issue:21 Topics: Aflatoxin B1; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Disease Models, Animal; Down-Regulation; Emodin; Interleukin-1beta; Lipid Peroxidation; Liver; Male; Rats	2021
Aloin alleviates pathological cardiac hypertrophy via modulation of the oxidative and fibrotic response. Life sciences, 2022, Jan-01, Volume: 288 Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Cardiomegaly; Cathartics; Emodin; Fibrosis; Isoproterenol; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley	2022
[Aloin inhibits lactate-induced proliferation and migration of gastric cancer cells by downregulating HMGB1 expression]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021, Nov-20, Volume: 41, Issue:11 Topics: Cell Line, Tumor; Cell Proliferation; Emodin; Gene Expression Regulation, Neoplastic; HMGB1 Protein; Humans; Lactic Acid; Stomach Neoplasms	2021
The absence of genotoxicity of a mixture of aloin A and B and a commercial aloe gel beverage. Toxicology mechanisms and methods, 2022, Volume: 32, Issue:5 Topics: Aloe; Beverages; DNA Damage; Emodin; Plant Extracts	2022
Iron supplementation ameliorates aloin-induced iron deficiency anemia in rats. Experimental and molecular pathology, 2022, Volume: 124 Topics: Anemia, Iron-Deficiency; Animals; Dietary Supplements; Emodin; Erythropoiesis; Glycosides; Hepcidins; Iron; Iron Deficiencies; Liver; Rats; Receptors, Transferrin; Spleen	2022
Inhibitory effects of aloin on lipopolysaccharide-induced severe inflammatory responses. Journal of Asian natural products research, 2022, Volume: 24, Issue:10 Topics: Animals; Anti-Inflammatory Agents; Cell Adhesion Molecules; Emodin; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Molecular Structure; NF-kappa B; Tumor Necrosis Factor-alpha	2022
Aloin isoforms (A and B) selectively inhibits proteolytic and deubiquitinating activity of papain like protease (PLpro) of SARS-CoV-2 in vitro. Scientific reports, 2022, 02-09, Volume: 12, Issue:1 Topics: Animals; Binding Sites; Cell Survival; Chlorocebus aethiops; Coronavirus 3C Proteases; Coronavirus Papain-Like Proteases; COVID-19; Emodin; Humans; Molecular Dynamics Simulation; Protein Isoforms; SARS-CoV-2; Vero Cells	2022
Structural and mechanistic insights into modulation of α-Synuclein fibril formation by aloin and emodin. Biochimica et biophysica acta. General subjects, 2022, Volume: 1866, Issue:7 Topics: alpha-Synuclein; Amyloid; Emodin; Humans; Parkinson Disease	2022
Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Aloin Against Gastric Cancer. Drug design, development and therapy, 2022, Volume: 16 Topics: Emodin; Humans; Molecular Docking Simulation; Network Pharmacology; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Stomach Neoplasms	2022
Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the Notch signaling pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 106 Topics: Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Emodin; Interleukin-10; Interleukin-6; Intestinal Mucosa; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Occludin; Prospective Studies; Signal Transduction; Tight Junction Proteins; Tumor Necrosis Factor-alpha; Water	2022
In vivo metabolism combined network pharmacology to identify anti-constipation constituents in Aloe barbadensis Mill. Journal of ethnopharmacology, 2024, Jan-30, Volume: 319, Issue:Pt 1 Topics: Aloe; Animals; Constipation; Emodin; Network Pharmacology; Plant Extracts; Rats; Tandem Mass Spectrometry	2024
Studies of aloe. V. Mechanism of cathartic effect. (4). Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:5 Topics: Aloe; Animals; Anthracenes; Anthraquinones; Body Water; Cathartics; Chromatography, Thin Layer; Densitometry; Emodin; Feces; Intestinal Mucosa; Male; Mucus; Peristalsis; Plants, Medicinal; Rats; Rats, Wistar	1994
A purgative action of barbaloin is induced by Eubacterium sp. strain BAR, a human intestinal anaerobe, capable of transforming barbaloin to aloe-emodin anthrone. Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:1 Topics: Animals; Anthracenes; Anthraquinones; Cathartics; Culture Media; Diarrhea; Emodin; Eubacterium; Feces; Intestines; Male; Rats; Rats, Wistar	1996
[Contents of barbaloin-related compounds in aloe drinks and their change during storage]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2002, Volume: 43, Issue:3 Topics: Aloe; Anthracenes; Anthraquinones; Emodin; Food Analysis; Food Preservation; Temperature; Time Factors	2002
The quantitative conversion of barbaloin to aloe-emodin and its application to the evaluation of aloes. The Journal of pharmacy and pharmacology, 1963, Volume: 15 Topics: Aloe; Anthracenes; Anthraquinones; Emodin; Humans	1963
Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin. Biochemical pharmacology, 2004, Aug-01, Volume: 68, Issue:3 Topics: Anthracenes; Anthraquinones; Drug Delivery Systems; Emodin; Liposomes; Membranes; Phosphatidylglycerols; Spectrometry, Fluorescence; Temperature	2004
Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice: investigation on hypoglycemic action and systemic absorption dynamics of aloe components. Journal of ethnopharmacology, 2006, Feb-20, Volume: 103, Issue:3 Topics: Aloe; Animals; Anthracenes; Blood Glucose; Diabetes Mellitus, Experimental; Diet; Emodin; Female; Glucosides; Hypoglycemic Agents; Insulin; Intestinal Absorption; Islets of Langerhans; Mice; Mice, Inbred ICR; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tissue Distribution	2006

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