Page last updated: 2024-08-24

emivirine and tnk-651

emivirine has been researched along with tnk-651 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Esnouf, RM; Hopkins, AL; Jones, EY; Miyasaka, T; Ren, J; Ross, C; Stammers, DK; Stuart, DI; Tanaka, H; Walker, RT; Willcox, BE1
Kang, X; Kollman, PA; Kuntz, ID; Wang, J1
Huang, Y; Jiang, S; Li, L; Liu, C; Liu, J; Ma, L; Ouyang, Y; Qiao, K; Shao, Y; Wang, R; Wang, X; Xu, W; Zhang, J; Zhang, L; Zhang, Z1
Danel, K; La Colla, P; Larsen, LM; Loddo, R; Pedersen, EB; Sanna, G1
El-Brollosy, NR; Loddo, R1

Other Studies

5 other study(ies) available for emivirine and tnk-651

ArticleYear
Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.
    Journal of medicinal chemistry, 1996, Apr-12, Volume: 39, Issue:8

    Topics: Antiviral Agents; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Protein Conformation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship

1996
Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and MM-PB/SA.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Allosteric Site; Anti-HIV Agents; Crystallography, X-Ray; Databases, Factual; Drug Design; HIV Reverse Transcriptase; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Statistics as Topic; Thermodynamics

2005
Design, synthesis, and biological evaluation of 1-[(2-benzyloxyl/alkoxyl)methyl]-5-halo-6-aryluracils as potent HIV-1 non-nucleoside reverse transcriptase inhibitors with an improved drug resistance profile.
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Models, Molecular; Structure-Activity Relationship; Uracil

2012
Synthesis and antiviral activity of new dimeric inhibitors against HIV-1.
    Bioorganic & medicinal chemistry, 2008, Jan-01, Volume: 16, Issue:1

    Topics: Anti-HIV Agents; Dimerization; HIV-1; Humans; Mutation; Pyrimidines; Uracil; Zidovudine

2008
Synthesis and Antiviral Evaluation of 1-[(2-Phenoxyethyl)oxymethyl] and 6-(3,5-Dimethoxybenzyl) Analogues of HIV Drugs Emivirine and TNK-651.
    Drug research, 2016, Volume: 66, Issue:4

    Topics: Anti-HIV Agents; Cell Line; HIV-1; Microbial Sensitivity Tests; Molecular Structure; Mutation; Pyrimidines; Structure-Activity Relationship; Uracil

2016