Page last updated: 2024-08-24

emivirine and efavirenz

emivirine has been researched along with efavirenz in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's10 (76.92)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artico, M; Greco, G; La Colla, M; La Colla, P; Lavecchia, A; Loddo, R; Mai, A; Massa, S; Murgioni, C; Musiu, C; Novellino, E; Ragno, R; Sbardella, G1
Jorgensen, WL; Rizzo, RC; Tirado-Rives, J; Wang, DP1
Jorgensen, WL; Kroeger Smith, MB; Rizzo, RC; Smith, RH; Tirado-Rives, J; Udier-Blagović, M; Wang, DP; Watkins, EK1
Andries, K; Benjahad, A; Grierson, DS; Guillemont, J; Nguyen, CH1
Artico, M; Cadeddu, A; La Colla, P; Mai, A; Marturana, F; Massa, S; Mura, M; Musiu, C; Ragno, R; Sbardella, G1
Andries, K; Benjahad, A; Bisagni, E; Coupa, S; Courté, K; Csoka, I; de Béthune, MP; Grierson, DS; Guillemont, J; Mabire, D; Monneret, C; Nguyen, CH; Pauwels, R; Poncelet, A1
Kang, X; Kollman, PA; Kuntz, ID; Wang, J1
Danel, K; La Colla, P; Larsen, LM; Loddo, R; Pedersen, EB; Sanna, G1
Collu, G; Giliberti, G; La Colla, P; Loddo, R; Loksha, YM; Pedersen, EB; Sanna, G1
Crowe, S1
Duval, X1
Balzarini, J; Burt, V; Carbonez, A; De Clercq, E; Kleim, JP1
Decha, P; Hannongbua, S; Intharathep, P; Parasuk, V; Sompornpisut, P; Udommaneethanakit, T; Wolschann, P1

Reviews

1 review(s) available for emivirine and efavirenz

ArticleYear
New reverse transcriptase inhibitors.
    Advances in experimental medicine and biology, 1999, Volume: 458

    Topics: Adenine; Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Dideoxynucleosides; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nevirapine; Organophosphonates; Oxazines; Prodrugs; Reverse Transcriptase Inhibitors; Soman; Uracil

1999

Other Studies

12 other study(ies) available for emivirine and efavirenz

ArticleYear
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Journal of medicinal chemistry, 2001, Aug-02, Volume: 44, Issue:16

    Topics: Animals; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Models, Molecular; Molecular Conformation; Mutation; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2001
Antiviral drug design: computational analyses of the effects of the L100I mutation for HIV-RT on the binding of NNRTIs.
    Bioorganic & medicinal chemistry letters, 2001, Nov-05, Volume: 11, Issue:21

    Topics: Drug Design; HIV Reverse Transcriptase; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors

2001
Prediction of activity for nonnucleoside inhibitors with HIV-1 reverse transcriptase based on Monte Carlo simulations.
    Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14

    Topics: Alkynes; Anilides; Benzoxazines; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Nevirapine; Oxazines; Protein Binding; Quinoxalines; Regression Analysis; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2002
3-iodo-4-phenoxypyridinones (IOPY's), a new family of highly potent non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2003, Dec-15, Volume: 13, Issue:24

    Topics: HIV-1; Models, Molecular; Molecular Conformation; Pyridones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2003
Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C varia
    Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4

    Topics: Cell Line; Computer Simulation; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Models, Molecular; Mutation; Pyrimidinones; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors

2004
4-benzyl- and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones, a new family of potent anti-HIV agents: optimization and in vitro evaluation against clinically important HIV mutant strains.
    Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22

    Topics: Alkynes; Aminopyridines; Anti-HIV Agents; Benzene Derivatives; Benzoates; Benzoxazines; Cell Line; Cyclopropanes; HIV-1; Humans; Mutagenesis, Site-Directed; Mutation; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2004
Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and MM-PB/SA.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Allosteric Site; Anti-HIV Agents; Crystallography, X-Ray; Databases, Factual; Drug Design; HIV Reverse Transcriptase; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Statistics as Topic; Thermodynamics

2005
Synthesis and antiviral activity of new dimeric inhibitors against HIV-1.
    Bioorganic & medicinal chemistry, 2008, Jan-01, Volume: 16, Issue:1

    Topics: Anti-HIV Agents; Dimerization; HIV-1; Humans; Mutation; Pyrimidines; Uracil; Zidovudine

2008
Synthesis of novel fluoro analogues of MKC442 as microbicides.
    Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12

    Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2014
[The 39th ICAAC (San Francisco) and the 7th European Conference on Clinical Aspects and Treatment of HIV-infection (Lisbon). HIV infection: antiretroviral agents in the development and trial stage].
    Presse medicale (Paris, France : 1983), 2000, Feb-12, Volume: 29, Issue:5

    Topics: Alkynes; Animals; Anti-HIV Agents; Antiviral Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Oxazines; Quinoxalines; Reverse Transcriptase Inhibitors; Time Factors; Uracil; Viral Load

2000
Long-term exposure of HIV type 1-infected cell cultures to combinations of the novel quinoxaline GW420867X with lamivudine, abacavir, and a variety of nonnucleoside reverse transcriptase inhibitors.
    AIDS research and human retroviruses, 2000, Apr-10, Volume: 16, Issue:6

    Topics: Alkynes; Anilides; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Microbial; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation; Nevirapine; Oxazines; Quinoxalines; Reverse Transcriptase Inhibitors; Thioamides; Uracil

2000
Theoretical studies on the molecular basis of HIV-1RT/NNRTIs interactions.
    Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:1

    Topics: Alkynes; Amino Acids; Benzoxazines; Binding Sites; Cyclopropanes; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Biological; Molecular Dynamics Simulation; Mutation; Nevirapine; Nitriles; Protein Binding; Protein Conformation; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Thermodynamics; Uracil; Water

2011