Page last updated: 2024-08-24

emitefur and fluorouracil

emitefur has been researched along with fluorouracil in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.41)18.7374
1990's20 (74.07)18.2507
2000's5 (18.52)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujii, S; Fukushima, M; Imaoka, T; Kimura, A; Kimura, Y; Ohshimo, H; Shimamoto, Y; Shirasaka, T; Utsunomiya, T1
Fujii, S; Fujita, F; Fujita, M; Fukushima, M; Shirasaka, T; Taguchi, T1
Fujii, S; Fukushima, M; Imaoka, T; Ohshimo, H; Shimamoto, Y; Shirasaka, T1
Fujii, S1
Asakawa, M; Fujii, M; Fukuoka, M; Furuse, K; Nakai, Y; Niitani, H; Ohta, M; Yamaguchi, Y; Yoshida, K1
Ichihara, N; Imaoka, T; Miyauchi, S; Motoyama, M1
Fujita, F; Fujita, M; Sakamoto, Y1
Hayashi, K; Imaoka, T; Kawaguchi, T; Kubo, M; Matsui, Y; Miyauchi, S; Utsunomiya, T1
Awogi, T; Itoh, T; Kaneko, E; Kirkland, DJ; Marshall, RR; Shibahara, T; Takahashi, N; Tsushimoto, G1
Fujita, F; Fujita, M; Sakamoto, Y; Taguchi, T1
Taguchi, T1
Fujita, F; Fujita, M; Inaba, H; Taguchi, T1
Hiraoka, M; Hirohashi, M; Miyauchi, S; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Takagi, T1
Akiyama, H; Imaoka, T; Kawaguchi, T; Miyauchi, S; Motoyama, M; Odomi, M; Okada, T1
Sakata, Y; Suzuki, H; Takemori, H1
Kobayashi, K1
Hirohashi, M; Miyauchi, S; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Takagi, T; Takahashi, M1
Sasaki, T1
Osaki, T; Ueta, E; Yamamoto, T; Yoneda, K1
Brito, RA; Hoff, PM; Medgyesy, D; Pazdur, R; Ravandi-Kashani, F; Royce, ME; Zukowski, TH1
Diasio, RB2
Brito, R; Hoff, PM; Medgyesy, D; Pazdur, R; Royce, M1
Corey, A; Eager, R; Hoff, PM; Nemunaitis, J; Pazdur, R; Sekar, K; Thompson, J; Tkaczuk, K; Twaddell, T1
Maehara, Y; Sugimachi, K1
Hoff, PM; Saad, ED1
Eng, C; Kindler, HL; Schilsky, RL1

Reviews

10 review(s) available for emitefur and fluorouracil

ArticleYear
[Development of fluorinated pyrimidines in Japan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Fluorodeoxyuridylate; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasms; Neoplasms, Experimental; Oxonic Acid; Pyridines; Rats; Tegafur

1993
[Chemotherapy for pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Deoxycytidine; Docetaxel; Fluorouracil; Gemcitabine; Humans; Interferon-alpha; Irinotecan; Leucovorin; Paclitaxel; Pancreatic Neoplasms; Quality of Life; Taxoids

1996
[Clinical use of platinum compounds and fluorinated pyrimidines for lung cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:13

    Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Drug Combinations; Fluorouracil; Humans; Lung Neoplasms; Tegafur; Uracil

1996
[New anti-cancer drugs for gastrointestinal cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:13

    Topics: Amino Acids; Antidotes; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials, Phase II as Topic; Docetaxel; Drug Administration Schedule; Fluorouracil; Gastrointestinal Neoplasms; Humans; Interferons; Irinotecan; Leucovorin; Paclitaxel; Taxoids

1997
Fluoropyrimidines: a critical evaluation.
    Oncology, 1999, Volume: 57 Suppl 1

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Leucovorin; Oxonic Acid; Pyridines; Tegafur; Uracil

1999
Clinical implications of dihydropyrimidine dehydrogenase inhibition.
    Oncology (Williston Park, N.Y.), 1999, Volume: 13, Issue:7 Suppl 3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Dihydrouracil Dehydrogenase (NADP); Drug Evaluation; Enzyme Inhibitors; Fluorouracil; Humans; Neoplasms; Oxidoreductases; Tegafur; Uracil

1999
Oral fluoropoyrimidines.
    Seminars in oncology, 1999, Volume: 26, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Folic Acid Antagonists; Humans; Leucovorin; Oxidoreductases; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil

1999
Oral DPD-inhibitory fluoropyrimidine drugs.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:10 Suppl 9

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Humans; Leucovorin; Oxidoreductases; Oxonic Acid; Pyridines; Tegafur; Uracil

2000
Other fluorinated pyrimidines in the treatment of solid tumors.
    Oncology (Williston Park, N.Y.), 2001, Volume: 15, Issue:1 Suppl 2

    Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Drug Combinations; Fluorouracil; Humans; Neoplasms; Oxonic Acid; Pyridines; Tegafur

2001
Oral fluoropyrimidine treatment of colorectal cancer.
    Clinical colorectal cancer, 2001, Volume: 1, Issue:2

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Cost-Benefit Analysis; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Patient Compliance; Prodrugs; Pyridines; Tegafur; Treatment Outcome

2001

Trials

3 trial(s) available for emitefur and fluorouracil

ArticleYear
Efficacy of a new 5-fluorouracil derivative, BOF-A2, in advanced non-small cell lung cancer. A multi-center phase II study.
    Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Anemia; Antineoplastic Agents; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nausea; Thrombocytopenia; Vomiting

1994
Phase I assessment of the pharmacokinetics, metabolism, and safety of emitefur in patients with refractory solid tumors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Oct-01, Volume: 18, Issue:19

    Topics: Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms

2000
A phase II trial of a new 5-fluorouracil derivative, BOF-A2 (Emitefur), for patients with advanced gastric cancer.
    Surgery today, 2000, Volume: 30, Issue:12

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Disease Progression; Female; Fluorouracil; Humans; Male; Middle Aged; Stomach Neoplasms; Survival Analysis; Treatment Outcome

2000

Other Studies

14 other study(ies) available for emitefur and fluorouracil

ArticleYear
[Metabolic characteristics and antitumor activity of BOF-A2, a new 5-fluorouracil derivative].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:5

    Topics: Animals; Antineoplastic Agents; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Rats

1990
[Antitumor activity and metabolism of BOF-A2, a new 5-fluorouracil derivative, with human cancers xenografted in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:9

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Colorectal Neoplasms; Fluorouracil; Humans; Liver; Mice; Mice, Nude; Microsomes; Neoplasm Transplantation; Neoplasms, Experimental; Pancreatic Neoplasms; Stomach Neoplasms

1990
Antitumor activity of BOF-A2, a new 5-fluorouracil derivative.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Fluorouracil; Mice; Mice, Inbred ICR; Pyridines; Rats; Sarcoma 180; Sarcoma, Yoshida

1989
[BOF-A1 and BOF-A2, new 5-FU degradation-inhibitory agents].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Floxuridine; Fluorouracil; Liver; Mice; Pyridines; Pyrimidines; Rats; Sarcoma 180; Sarcoma, Experimental; Sarcoma, Yoshida; Tegafur; Uracil

1987
[Effect of BOF-A2 on experimental and spontaneous metastasis model of mouse colon 26].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Chemotherapy, Adjuvant; Colonic Neoplasms; Fluorouracil; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation

1994
[Combination chemotherapy of BOF-A2, a new 5-FU derivative, with various anticancer agents against human cancer xenografts in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:10

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Female; Fluorouracil; Humans; Interferon-alpha; Irinotecan; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasm Transplantation; Transplantation, Heterologous

1994
Oral administration of BOF-A2 to rats with lung transplanted tumors results in increased 5-fluorouracil levels.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:6

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Combinations; Drug Interactions; Fluorouracil; Lung; Lung Neoplasms; Male; Neoplasm Transplantation; Pyridines; Rats; Sarcoma, Yoshida; Tegafur; Transplantation, Heterologous; Uracil

1994
Mutagenic and clastogenic properties of (3-[3-(6-benzoyloxy-3-cyano-2- pyridyloxycarbonyl) benzoyl]-1-ethoxymethyl-5-fluorouracil) (BOF-A2), a new 5-fluorouracil derivative with anti-tumour activity.
    The Journal of toxicological sciences, 1993, Volume: 18 Suppl 3

    Topics: Animals; Antineoplastic Agents; Bone Marrow; CHO Cells; Chromosome Aberrations; Cricetinae; Escherichia coli; Fluorouracil; In Vitro Techniques; Mice; Micronucleus Tests; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium

1993
[Antitumor activity of combination treatment of BOF-A2 with CDDP against human lung cancers xenografted in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:2

    Topics: Adenocarcinoma, Papillary; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation

1993
[Antitumor activity of BOF-A2, a new 5-fluorouracil derivative, against human cancers xenografted in nude mice by intermittent administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Stomach Neoplasms; Tegafur; Uracil

1993
The combined antitumour effect of a new 5-fluorouracil derivative, BOF-A2, and radiation in vivo.
    The British journal of cancer. Supplement, 1996, Volume: 27

    Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Fluorouracil; Mice; Mice, Inbred C3H; Neoplasms, Experimental

1996
Leukopenia-inducing effect of a combination of a new 5-fluorouracil (5-FU)-derived drug, BOF-A2 (emitefur), with other 5-FU-derived drugs or BV-araU (sorivudine) in rats.
    Japanese journal of pharmacology, 1996, Volume: 70, Issue:2

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Arabinofuranosyluracil; Dose-Response Relationship, Drug; Drug Combinations; Fluorouracil; Leukopenia; Male; Rats; Rats, Sprague-Dawley

1996
Combined effect of clinically relevant doses of emitefur, a new 5-fluorouracil derivative, and radiation in murine tumours.
    British journal of cancer, 1996, Volume: 74, Issue:11

    Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Tumor Stem Cell Assay

1996
The inhibitory action of BOF-A2, a 5-fluorouracil derivative, on squamous cell carcinoma.
    Cancer letters, 1999, Mar-22, Volume: 137, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; DNA, Neoplasm; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Proliferating Cell Nuclear Antigen

1999