Page last updated: 2024-08-21

emetine and methotrexate

emetine has been researched along with methotrexate in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's1 (5.00)18.2507
2000's2 (10.00)29.6817
2010's8 (40.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Boesche, M; Crowther, GJ; Dasari, KS; Drewes, G; El Bakkouri, M; Fox, AM; Ghidelli-Disse, S; He, P; Hillesland, HK; Hui, R; Jones, JC; Keyloun, KR; Krahn, MM; Lafuente-Monasterio, MJ; Leonard, SE; Leroy, D; Maly, DJ; Mo, JS; Ojo, KK; Reid, MC; Rivas, KL; Van Voorhis, WC1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
Furusawa, E; Furusawa, S; Lee, JY; Suzuki, N1
Depierre, A; Israel, L1
Gang, M; Kline, I; Sirica, AE; Venditti, JM; Woodman, RJ1
Israel, L1
Johnston, GS; Jones, AE1
Carter, RF1
Duff, C; Flintoff, W; Worton, R1
Barratt, G; Døskeland, SO; Herfindal, L; Myhren, L; Nicolas, V; Nilssen, IM1

Reviews

1 review(s) available for emetine and methotrexate

ArticleYear
Drugs for the Treatment of Zika Virus Infection.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection

2020

Other Studies

19 other study(ies) available for emetine and methotrexate

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Antimalarials; Calcium; Cell Line, Tumor; Hep G2 Cells; Humans; Malaria, Falciparum; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Plasmodium falciparum; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protozoan Proteins

2016
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
Combination chemotherapy of Rauscher leukemia and ascites tumors by narcissus alkaloid with standard drugs and effect on cellular immunity.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 149, Issue:3

    Topics: Alkaloids; Animals; Antineoplastic Agents; Azacitidine; Blood Cells; Carcinoma, Ehrlich Tumor; Carmustine; Cells, Cultured; Cyclophosphamide; Dactinomycin; Daunorubicin; Drug Synergism; Drug Therapy, Combination; Emetine; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Mice; Mice, Inbred BALB C; Plants, Medicinal; Rauscher Virus; Spleen; Streptonigrin; Vincristine

1975
[Recent personal results in advanced bronchial cancer. Palliative immuno-chemotherapy. 63 cases].
    Annales de medecine interne, 1976, Volume: 127, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Emetine; Female; Fluorouracil; Humans; Immunotherapy; Lomustine; Male; Methotrexate; Middle Aged; Mitomycins; Palliative Care; Propionibacterium acnes; Vincristine

1976
The enhanced therapeutic effect of cis-platinum (II) diamminodichloride against L1210 leukemia when combined with cyclophosphamide or 1,2-bis(3,5-dioxopiperazine-1-yl)propane or several other antitumor agents.
    Chemotherapy, 1973, Volume: 18, Issue:3

    Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Carmustine; Chlorides; Cyclophosphamide; Cytarabine; Drug Synergism; Emetine; Fluorouracil; Ketones; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Piperazines; Platinum; Propane; Time Factors

1973
[Palliative chemotherapy of bronchial cancers. Current status of the problem].
    Le Poumon et le coeur, 1973, Volume: 29, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Emetine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Mitomycins; Mustard Compounds; Palliative Care; Procarbazine; Thiotepa; Vinblastine

1973
Sequential liver scanning.
    Journal of surgical oncology, 1969, Volume: 1, Issue:3

    Topics: Adult; Breast Neoplasms; Chloroquine; Colonic Neoplasms; Dactinomycin; Emetine; Estrogens; Female; Fluorouracil; Gold Colloid, Radioactive; Humans; Liver Abscess, Amebic; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Radionuclide Imaging; Thiotepa

1969
Sensitivity to amphotericin B of a Naegleria sp. isolated from a case of primary amoebic meningoencephalitis.
    Journal of clinical pathology, 1969, Volume: 22, Issue:4

    Topics: Amebiasis; Amoeba; Amphotericin B; Animals; Chloramphenicol; Emetine; Humans; Meningoencephalitis; Methotrexate; Metronidazole; Mice; Oxytetracycline; Penicillins; Quinine; Streptomycin; Sulfadiazine

1969
Microcell-mediated cotransfer of genes specifying methotrexate resistance, emetine sensitivity, and chromate sensitivity with Chinese hamster chromosome 2.
    Molecular and cellular biology, 1981, Volume: 1, Issue:4

    Topics: Animals; Cell Line; Chromates; Chromosome Mapping; Cricetinae; Cricetulus; Drug Resistance; Emetine; Genetic Markers; Methotrexate; Phenotype; Transfection

1981
Efficacy of multi-functional liposomes containing daunorubicin and emetine for treatment of acute myeloid leukaemia.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2014, Volume: 88, Issue:1

    Topics: Anthracyclines; Cell Line, Tumor; Chromatography, High Pressure Liquid; Daunorubicin; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Resistance; Emetine; Flow Cytometry; Folate Receptor 2; Humans; Leukemia, Myeloid, Acute; Light; Liposomes; Male; Methotrexate; Polyethylene Glycols; Prostatic Neoplasms; Scattering, Radiation; Tumor Suppressor Protein p53

2014