Page last updated: 2024-08-21

emetine and cyclosporine

emetine has been researched along with cyclosporine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (29.41)18.2507
2000's5 (29.41)29.6817
2010's5 (29.41)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Smyth, MJ1
Chen, CA; Collins, JL; Herzog, TJ; Mutch, DG1
Garcia-Sanz, JA; Lichtenheld, MG; Lu, P; Podack, ER1
Antoni, F; Apati, A; Banfalvi, G; Lapis, K; Molnar, G; Schweighoffer, E; Schweighoffer, T1
Braciale, VL; Dinglasan, RD; Esser, MT; Graham, MB; Gullo, CA; Krishnamurthy, B1
Avetisyan, AV; Bakeeva, LE; Chernyak, BV; Fetisova, EK; Izyumov, DS; Pletjushkina, OY; Saprunova, VB; Shchepina, LA; Skulachev, VP; Vyssokikh, MY1

Other Studies

17 other study(ies) available for emetine and cyclosporine

ArticleYear
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Mechanisms of cytotoxicity used by human peripheral blood T-cell subsets.
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Bucladesine; CD4 Antigens; CD8 Antigens; Cholera Toxin; Cycloheximide; Cyclosporine; Cytotoxicity, Immunologic; Dactinomycin; Egtazic Acid; Emetine; Humans; Lymphocyte Activation; Mitomycin; T-Lymphocyte Subsets; Tumor Necrosis Factor-alpha

1992
The effects of cyclosporin A on the lysis of ovarian cancer cells by cisplatin or adriamycin.
    Gynecologic oncology, 1992, Volume: 47, Issue:1

    Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Death; Cisplatin; Cycloheximide; Cyclosporine; Doxorubicin; Drug Interactions; Drug Resistance; Emetine; Female; Humans; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil

1992
Perforin expression in human peripheral blood mononuclear cells. Definition of an IL-2-independent pathway of perforin induction in CD8+ T cells.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Jun-01, Volume: 148, Issue:11

    Topics: Base Sequence; Calcimycin; Calcium; CD8 Antigens; Cell Adhesion; Cyclosporine; Emetine; Gene Expression; Granzymes; Humans; Interleukin-2; Leukocytes, Mononuclear; Membrane Glycoproteins; Membrane Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Perforin; Pore Forming Cytotoxic Proteins; RNA, Messenger; Serine Endopeptidases; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Time Factors

1992
Cytometric analysis of DNA replication inhibited by emetine and cyclosporin A.
    Histochemistry, 1991, Volume: 96, Issue:1

    Topics: Animals; Biotin; Cyclosporine; Deoxyuracil Nucleotides; DNA Replication; Emetine; Flow Cytometry; Humans; Male; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; T-Lymphocytes; Thymus Gland; Tumor Cells, Cultured

1991
IL-2 induces Fas ligand/Fas (CD95L/CD95) cytotoxicity in CD8+ and CD4+ T lymphocyte clones.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Jun-15, Volume: 158, Issue:12

    Topics: Antigens, Surface; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Clone Cells; Cyclosporine; Cytotoxicity, Immunologic; Emetine; Fas Ligand Protein; fas Receptor; Humans; Immunosuppressive Agents; Interleukin-2; Membrane Glycoproteins; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Th1 Cells; Th2 Cells

1997
Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis.
    Oncogene, 2002, Nov-21, Volume: 21, Issue:53

    Topics: Aurovertins; Cyclosporine; Cytochrome c Group; Cytosol; Deoxyglucose; Emetine; Enzyme Inhibitors; Genes, bcl-2; HeLa Cells; Humans; Ion Channels; Membrane Potentials; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neoplasm Proteins; Oligomycins; Proto-Oncogene Proteins c-bcl-2; Proton-Translocating ATPases; Recombinant Fusion Proteins; Recombinant Proteins; Staurosporine; Transfection; Tumor Necrosis Factor-alpha; Uncoupling Agents

2002