emetine has been researched along with cycloheximide in 202 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 145 (71.78) | 18.7374 |
| 1990's | 35 (17.33) | 18.2507 |
| 2000's | 14 (6.93) | 29.6817 |
| 2010's | 5 (2.48) | 24.3611 |
| 2020's | 3 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Dunbar, DC; Jones, DK; Kim, YP; Mohammed, KA; Muhammad, I; Nagle, DG; Zhou, YD | 1 |
| Bender, A; Chirn, GW; Feng, Y; Hoyt, J; Jenkins, JL; Labow, M; McWhinnie, E; Mitchison, TJ; Tallarico, JA; Tao, CY; Young, DW | 1 |
| Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y | 1 |
| Boesche, M; Crowther, GJ; Dasari, KS; Drewes, G; El Bakkouri, M; Fox, AM; Ghidelli-Disse, S; He, P; Hillesland, HK; Hui, R; Jones, JC; Keyloun, KR; Krahn, MM; Lafuente-Monasterio, MJ; Leonard, SE; Leroy, D; Maly, DJ; Mo, JS; Ojo, KK; Reid, MC; Rivas, KL; Van Voorhis, WC | 1 |
| Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Freikopf, A; Kulka, RG | 1 |
| Baccino, FM; Cecchini, G; Palmucci, F; Sverko, V; Tessitore, L; Zuretti, MF | 1 |
| DeLap, L; Ernest, MJ; Feigelson, P | 1 |
| Andrulis, IL; Arfin, SM; Hatfield, GW | 1 |
| Walker, E; Wheatley, DN | 1 |
| McCormick, FP; Newton, AA | 1 |
| Moore, PB; Mulvihill, ER; Palmiter, RD | 1 |
| Dunn, AJ; Gray, HE; Iuvone, PM | 1 |
| Birge, CH; Jen, G; Thach, RE | 1 |
| Jones, PC; Roizman, B | 1 |
| Kovács, J; Réz, G | 2 |
| Ford, SC; Granger, GA; Harris, PC; Hiserodt, JC | 1 |
| Carrasco, L; Jiménez, A; Vázquez, D | 2 |
| Evans, RT; Taylor-Robinson, D | 1 |
| Laux, DC; Moody, CE; Tunticharoen, M | 1 |
| Kuwano, M; Ono, M; Takenaka, K | 1 |
| Hong, SL; Levine, L; Pong, SS | 1 |
| Gupta, RS; Siminovitch, L | 1 |
| Roufa, DJ | 1 |
| Avadhani, NG; Lewis, FS; Rutman, RJ | 1 |
| Brinckerhoff, CE; Lubin, M | 1 |
| Oleinick, NL | 1 |
| Canning, EU; Sinden, RE; Toyé, PJ | 1 |
| Alscher, R; Criddle, RS; Huffaker, RC; Petersen, LW; Smith, MA | 1 |
| Ceccarini, C; Eagle, H | 1 |
| Craig, IW; Jeffreys, AJ | 1 |
| Lingrel, JB; Merkel, CG; Wood, TG | 1 |
| Bolcsfoldi, G; Eliasson, E; Westerberg, UB | 1 |
| Emmerich, B; Erben, V; Hoffman, H; Rastetter, J | 1 |
| Alscher, RG; Hawkes, SP; Sauer, K | 1 |
| Edwards, BF; Hylton, C; Marchalonis, JJ; Ruben, LN | 1 |
| Rillema, JA | 2 |
| Borst, P; Kleisen, CM | 1 |
| Craig, I; Jeffreys, A | 1 |
| Bailey, GB; Kusamrarn, T; Sobhon, P | 1 |
| Emmerich, B; Erben, V; Hoffmann, H | 1 |
| Clayton, DA; Lansman, RA | 1 |
| Doree, M; Guerrier, P | 1 |
| Del Prete, G; Gadaleta, MN; Greco, M; Saccone, C | 1 |
| Smyth, MJ | 1 |
| Gant, TW; Silverman, JA; Thorgeirsson, SS | 1 |
| Hwang, PL | 1 |
| Cassone, A; Djeu, JY; Palma, C; Pearson, CA; Serbousek, D | 1 |
| Chen, CA; Collins, JL; Herzog, TJ; Mutch, DG | 1 |
| Edwards, DR; Mahadevan, LC | 1 |
| Dickler, HB; Laszlo, G | 1 |
| László, L; Oliva, O; Pálfia, Z; Réz, G | 1 |
| Bhutada, A; Ismail-Beigi, F; Perez, C | 1 |
| Berglindh, T; Nygãard, G; Nygãrd, G | 1 |
| Singer, RH; Sundell, CL | 1 |
| Hozumi, N; Kakiuchi, T; Nariuchi, H; Watanabe, M | 1 |
| Joag, SV; Kwon, BS; Liu, CC; Young, JD | 1 |
| Cavanaugh, AH; Gokal, PK; Thompson, EA | 1 |
| Addison, WR; Kurtz, DT | 1 |
| Pelletier, DA; Pentz, WH; Ratner, DI | 1 |
| Poirot, MK; Reichmann, ME; Schnitzlein, WM | 1 |
| Kennedy, BG; Lever, JE | 1 |
| Cleveland, DW; Gay, DA; Sisodia, SS | 1 |
| Alvarado, MC; Bennett, EL; Patterson, TA; Rosenzweig, MR; Warner, IT | 1 |
| Groudine, M; Gunderson, N; Linial, M | 1 |
| Clark, WC; Doctor, J; Fristrom, JW; Hodgetts, RB | 1 |
| Fagan, JM; Goldberg, AL | 1 |
| Nathan, CF; Tsunawaki, S | 1 |
| Imashuku, S; Shimizu, Y; Todo, S | 2 |
| Belin, D; Collart, MA; Vassalli, JD; Vassalli, P | 1 |
| Klymkowsky, MW | 1 |
| Fujiwara, M; Fukushima, M; Narumiya, S; Ohno, K; Sakai, T | 1 |
| Chandrasena, G; Overberg, R; Rupert, CS | 1 |
| Das, M; Gauri, KK; Kumar, A; Manchanda, SK | 1 |
| Bantle, JA; Dawson, DA | 1 |
| Oppenheimer, JH; Perez-Castillo, A; Santos, A; Wong, NC | 1 |
| Bird, RC; Jacobs, FA; Sells, BH | 1 |
| Bantle, JA; Courchesne, CL; Dawson, DA | 1 |
| Price, DJ; Sherwin, JR | 1 |
| Hallberg, EM; Hallberg, RL; Kraus, KW | 1 |
| Borysko, K; Boskovich, S; Lemons, R; Thoene, JG | 1 |
| Itoh, K; Natori, S; Ueno, K | 1 |
| Ip, MM; Leung, KH | 1 |
| Fristrom, JW; Logan, WR; Murphy, C | 1 |
| Grollman, AP | 1 |
| Armstrong, JA; Ho, M; Tan, YH | 1 |
| Entner, N; Grollman, AP | 1 |
| Henney, CS | 1 |
| Lietman, PS | 1 |
| Carrico, CK; Hwang, KM; Sartorelli, AC; Schenkman, JB; Schulz, RA; Yang, LC | 1 |
| Antoni, F; Farkas, G; Piffkó, P; Staub, M | 1 |
| Bölcsföldi, G | 1 |
| Bertone, G; Gravela, E; Poli, G | 1 |
| Grahame-Smith, DG | 3 |
| Attardi, G; Costantino, P | 1 |
| Littlewood, BS | 1 |
| Chakrabarti, S; Dube, DK; Roy, SC | 2 |
| Grollman, AP; Huang, MT | 1 |
| Battaner, E; Carrasco, L; Vazquez, D | 1 |
| Attardi, G; Ojala, D | 1 |
| Burchill, BR; Plapp, FV | 1 |
| Elson, C; Shrago, E; Sondheimer, E; Yatvin, M | 1 |
| Stevens, RH; Williamson, AR | 1 |
| Avadhani, NG; Rutman, RJ | 1 |
| Orias, E; Roberts, CT | 1 |
| Stevens, RH | 1 |
| Pestka, S | 1 |
| Chou, SC; Conklin, KA | 1 |
| Baker, JB; Humphreys, T | 1 |
| Glazer, RI; Sartorelli, AC | 1 |
| Ho, M; Jeng, DK; Tan, YH | 1 |
| Housman, D; Jacobsen, M; Lodish, HG | 1 |
| Becker, Y; Gilead, Z | 1 |
| Coote, JL; Work, TS | 1 |
| Finkelstein, RA; Goth, A; Lexomboon, U | 1 |
| Bridgers, WF; Cunningham, RD; Gressett, G | 1 |
| Lodish, HF | 1 |
| Penman, S; Perlman, S | 1 |
| Neuwirt, J; Ponka, P | 1 |
| Beller, BM | 1 |
| Jondorf, WR; Szapary, D | 1 |
| Jermyn, MA | 1 |
| Baliga, BS; Munro, HN; Pronczuk, AW | 1 |
| Chappell, LH; Walker, E | 1 |
| Block, C; Diesterhaft, M; Granner, D; Hargrove, J; Noguchi, T; Olson, P; Seifert, S | 1 |
| Herberman, RB; Ortaldo, JR; Phillips, W; Wasserman, K | 1 |
| Alexandre, H; Brachet, J; de Petrocellis, B; Ficq, A | 1 |
| Aller, P; Diez, JL | 1 |
| Barovsky, K; Brooker, G; Pedone, C | 1 |
| deAlmeida, JC; Edström, JE | 1 |
| Ramabhadran, TV; Thach, RE | 1 |
| Handa, H; Sharp, PA | 1 |
| Agostini, C; Secchi, M; Venturelli, D | 1 |
| Johansson, P; Josefsson, JO | 2 |
| Brooker, G; Gibbs, JB | 1 |
| Mathinos, PR; Randall, JL; Ritter, EJ; Scott, WJ; Wilson, JG | 1 |
| Sarvey, JM; Stanton, PK | 1 |
| Lynch, RG; Milburn, GL | 1 |
| Agostini, C; Di Segni, M; Negrini, A | 1 |
| Dubiel, W; Dumdey, R; Müller, M; Rapoport, S; Siems, W | 1 |
| Blasi, E; Varesio, L | 1 |
| Baden, HP; Clendenning, W; Cornell, RC; Deneau, DD; Eaglstein, WH; Golub, A; King, L; Kulp, KR; Maibach, H; McCullough, JL; Stoughton, RB; Taylor, JS; Weinstein, GD; Zackheim, H | 1 |
| Kawamoto, S; Tatibana, M | 1 |
| Lipton, JH; Sachs, L | 1 |
| Csák, J; Kovács, AL; Kovács, J; Réz, G; Zboray, G | 1 |
| Bégueret, J; Chamla, Y | 1 |
| Nambu, Z; Yokoyama, E | 1 |
| Nuss, DL; Yates, JR | 1 |
| Dunlap, JC; Hastings, JW; Taylor, WR | 1 |
| Fischer, JJ; Machaj, JK; Weissberg, JB | 1 |
| Kiss, AL; Kovács, J; Réz, G | 1 |
| Chang, CC; Chang, TY; Limanek, JS | 1 |
| Djobadze, M; Hudig, D; Mendelsohn, J; Redelman, D | 1 |
| Fischer, JJ; Weissberg, JB | 1 |
| Jones, MH; Khym, JX; Lee, WH; Pike, LM; Volkin, E | 1 |
| Ballas, N; Koshiba, T; Theologis, A; Wong, LM | 1 |
| Hwang, PL; Lin, L; Low, YL; Ng, HL; Shoon, MY | 1 |
| Lee, YS; Wurster, RD | 1 |
| Chow, SC; Orrenius, S; Peters, I | 1 |
| Bicknell, GR; Cohen, GM; Snowden, RT | 1 |
| LaRue, KE; McCall, CE | 1 |
| Arnold, HH; Buchberger, A; Ragge, K | 1 |
| Apati, A; Balogh, A; Banfalvi, G; Csuka, I; Luat, NN; Schweighoffer, E; Schweighoffer, T; Sviresheva, M | 1 |
| Hochachka, PW; Land, SC | 1 |
| Kaur, G; Sartor, O; Sausville, EA; Sebers, S; Stetler-Stevenson, M; Worland, PJ | 1 |
| Hoffman, BB; Hu, ZW | 1 |
| Deppert, W; Knippschild, U; Oren, M | 1 |
| Kimura, K; Yamamoto, M | 1 |
| Choi, DW; Lobner, D | 1 |
| Kirimura, K; Matsui, T; Sugano, S; Usami, S | 1 |
| Begeot, M; Durand, P; Jaillard, C; Penhoat, A; Saez, JM | 1 |
| Lund, LR | 1 |
| Hitomi, M; Shu, J; Stacey, D | 1 |
| Duffey, DC; Fady, C; Gardner, AM; Jacoby, FJ; Lichtenstein, A; Tu, Y; Xu, FH | 1 |
| Blom, WM; de Bont, HJ; Meijerman, I; Mulder, GJ; Nagelkerke, JF | 1 |
| Bachhawat, AK; Kaur, R | 1 |
| Canzoniero, LM; Choi, WS; Gwag, BJ; Kim, JE; Lee, EB; O'Malley, KL; Oh, TH; Oh, YJ; Sensi, SL; Sohn, S | 1 |
| Fayadat, L; Franc, JL; Lanet, J; Siffroi-Fernandez, S | 1 |
| Dinh, TH; Iordanov, MS; Magun, BE; Newton, DL; Ryabinina, OP; Rybak, SM; Wong, J | 1 |
| Baker-Herman, TL; Mitchell, GS | 1 |
| Cornish, KL; Itani, OA; Liu, KZ; Thomas, CP | 1 |
| Arnqvist, HJ; Chisalita, S; Haarhaus, M; Söderlund, G | 1 |
| Afouda, BA; Ciau-Uitz, A; Patient, R | 1 |
| Boon-Unge, K; Govitrapong, P; Yu, Q; Zhou, A; Zhou, J; Zou, T | 1 |
| Bevilaqua, LR; Cammarota, M; Furini, CR; Izquierdo, I; Lima, RH; Rossato, JI | 1 |
| Cannon, E; Froscio, SM; Humpage, AR; Lau, HM | 1 |
| Carrier, L; Eschenhagen, T; Fraysse, B; Guiard, J; Hohenberg, H; Krämer, E; Mearini, G; Mougenot, N; Pointu, H; Reimer, R; Schlossarek, S; Schwartz, K; Vernet, M; Vignier, N | 1 |
| Abbas, AK; Ekström, J; Huang, FS; Li, R; Wigström, H | 1 |
| Ahmad, F; Blaesse, P; Kaila, K; Puskarjov, M | 1 |
| Bosch-Barrera, J; Corominas-Faja, B; Cuyàs, E; Martin-Castillo, B; Massaguer, A; Menendez, JA | 1 |
| Afset, JE; Bjørås, M; Ianevski, A; Kainov, DE; Oksenych, V; Tenson, T; Wang, W; Zusinaite, E | 1 |
3 review(s) available for emetine and cycloheximide
| Article | Year |
|---|---|
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization | 2021 |
Autophagocytosis.
Topics: Aflatoxins; Animals; Autophagy; Cell Membrane; Colchicine; Cyclic AMP; Cycloheximide; Dactinomycin; Emetine; Glucagon; Lysosomes; Microtubules; Phagocytosis; Polyribosomes; Proteins; Puromycin; Substrate Specificity; Tissue Distribution; Tubulin; Vinblastine; Vinca Alkaloids | 1979 |
Inhibitors of ribosome functions.
Topics: Alkaloids; Anti-Bacterial Agents; Bacterial Proteins; Chemical Phenomena; Chemistry; Chloramphenicol; Cyclohexanecarboxylic Acids; Cycloheximide; Emetine; Erythromycin; Escherichia coli; Genetic Code; Genetics, Microbial; Lincomycin; Models, Chemical; Puromycin; Ribosomes; RNA, Messenger; RNA, Transfer; Streptomycin; Tetracycline | 1971 |
1 trial(s) available for emetine and cycloheximide
| Article | Year |
|---|---|
A clinical screening program for topical chemotherapeutic drugs in psoriasis.
Topics: Adult; Animals; Clinical Trials as Topic; Cycloheximide; Dermatologic Agents; Double-Blind Method; Drug Evaluation, Preclinical; Emetine; Fluorouracil; Humans; Mitoguazone; Psoriasis; Pyrimethamine; Rabbits; Skin; Thiotepa | 1981 |
198 other study(ies) available for emetine and cycloheximide
| Article | Year |
|---|---|
Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells.
Topics: Alkaloids; Breast Neoplasms; DNA-Binding Proteins; Emetine; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Molecular Structure; Nuclear Proteins; Quinazolines; Rubiaceae; Terpenes; Tetrahydroisoquinolines; Transcription Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2005 |
Integrating high-content screening and ligand-target prediction to identify mechanism of action.
Topics: Antineoplastic Agents; Cell Cycle; Cell Nucleus; Cell Proliferation; Cluster Analysis; Computational Biology; DNA Replication; Dose-Response Relationship, Drug; Drug Design; HeLa Cells; Humans; Ligands; Models, Statistical; Molecular Structure; Predictive Value of Tests; Protein Binding; Small Molecule Libraries; Structure-Activity Relationship | 2008 |
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites | 2011 |
Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds.
Topics: Antimalarials; Calcium; Cell Line, Tumor; Hep G2 Cells; Humans; Malaria, Falciparum; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Plasmodium falciparum; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protozoan Proteins | 2016 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Involvement of protein synthesis in the post-translational control of glutamine synthetase activity of cultured hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Emetine; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver Neoplasms; Protein Biosynthesis | 1976 |
Biphasic effects of translational inhibitors on liver tyrosine aminotransferase.
Topics: Adrenalectomy; Animals; Cycloheximide; Emetine; Enzyme Induction; Hydrocortisone; Kinetics; Liver; Male; Protein Biosynthesis; Rats; Tyrosine Transaminase | 1977 |
Induction of hepatic tyrosine aminotransferase mRNA by protein synthesis inhibitors.
Topics: Animals; Bucladesine; Cyclic AMP; Cycloheximide; Emetine; Hydrocortisone; Liver; Male; Puromycin; Rats; RNA, Messenger; Theophylline; Transcription, Genetic; Tyrosine Transaminase | 1978 |
Asparaginyl-tRNA aminoacylation levels and asparagine synthetase expression in cultured Chinese hamster ovary cells.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Cell Line; Cricetinae; Cycloheximide; Emetine; Female; Kinetics; Leucine; Ligases; Mutation; Ovary; Protein Biosynthesis; RNA, Transfer; RNA, Transfer, Amino Acyl | 1979 |
Effects of hydrostatic pressure in the range 100-300 atmospheres on cell division and protein synthesis in synchronized Tetrahymena pyriformis: a comparison with cycloheximide and emetine.
Topics: Amino Acids; Animals; Cell Division; Cycloheximide; Dose-Response Relationship, Drug; Emetine; Hydrostatic Pressure; Pressure; Protein Biosynthesis; Tetrahymena pyriformis; Tritium | 1979 |
Polyamine metabolism in cells infected with herpes simplex virus.
Topics: Animals; Cycloheximide; Emetine; L Cells; Mice; Mitoguazone; Polyamines; Putrescine; Simplexvirus; Spermidine; Spermine; Tritium; Viral Plaque Assay; Virus Replication | 1975 |
A significant lag in the induction of ovalbumin messenger RNA by steroid hormones: a receptor translocation hypothesis.
Topics: Animals; Cell Nucleus; Chickens; Conalbumin; Cycloheximide; Emetine; Estradiol; Hydroxyurea; Kinetics; Models, Biological; Ovalbumin; Progesterone; Protein Biosynthesis; Receptors, Cell Surface; RNA, Messenger | 1976 |
Protein synthesis and amnesia: studies with emetine and pactamycin.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Amnesia; Animals; Anisomycin; Antibiotics, Antineoplastic; Avoidance Learning; Brain; Corticosterone; Cycloheximide; Depression, Chemical; Emetine; Humans; Liver; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Pactamycin; Protein Biosynthesis; Time Factors | 1977 |
Comparison of initiation rates of encephalomyocarditis virus and host protein synthesis in infected cells.
Topics: Animals; Anisomycin; Carcinoma, Krebs 2; Culture Techniques; Cycloheximide; Emetine; Encephalomyocarditis virus; Molecular Weight; Neoplasm Proteins; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; RNA, Messenger; RNA, Neoplasm; RNA, Viral; Viral Proteins | 1978 |
Regulation of herpesvirus macromolecular synthesis. VIII. The transcription program consists of three phases during which both extent of transcription and accumulation of RNA in the cytoplasm are regulated.
Topics: Base Sequence; Canavanine; Cell Line; Cell Nucleus; Cycloheximide; Cytoplasm; Emetine; Humans; Laryngeal Neoplasms; Nucleic Acid Conformation; RNA, Viral; Simplexvirus; Transcription, Genetic | 1979 |
The human LT system. VII. Release of soluble forms and delivery to target L-929 cells by lectin-preactivated human lymphocytes in the absence of protein synthesis and secretory processes.
Topics: Animals; Colchicine; Cycloheximide; Cytochalasin B; Cytotoxicity, Immunologic; Emetine; Humans; In Vitro Techniques; L Cells; Lectins; Lymphocyte Activation; Lymphocytes; Lymphotoxin-alpha; Mice; Protein Biosynthesis; Proteins | 1979 |
Enzymic and nonenzymic translocation by yeast polysomes. Site of action of a number of inhibitors.
Topics: Animals; Anti-Bacterial Agents; Cycloheximide; Emetine; Ethylmaleimide; Fusidic Acid; Kinetics; Mutation; Polyribosomes; Potassium; Protein Biosynthesis; Puromycin; Pyrans; Rabbits; Reticulocytes; Ribosomes; RNA, Transfer; Saccharomyces cerevisiae; Species Specificity | 1977 |
Comparison of various McCoy cell treatment procedures used for detection of Chlamydia trachomatis.
Topics: Bacteriological Techniques; Cells, Cultured; Chlamydia Infections; Chlamydia trachomatis; Cobalt Radioisotopes; Cycloheximide; Cytochalasin B; Emetine; Humans; Hydrocortisone; Idoxuridine; Male; Urethritis | 1979 |
Increased cell-mediated lysis of chicken erythrocytes following the addition of metabolic inhibitors.
Topics: Animals; Antibody Formation; Antimetabolites; Chickens; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Edetic Acid; Emetine; Erythrocytes; Immunity, Cellular; In Vitro Techniques; Pactamycin; Puromycin | 1977 |
The cross-resistance of mouse blasticidin S-resistant cell lines to puromycin and sparsomycin, inhibitors of ribosome function.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Cell Division; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Drug Resistance; Emetine; Guanidines; Kinetics; Mice; Mutation; Protein Biosynthesis; Puromycin; Ribosomes; Sparsomycin | 1979 |
Prostaglandin production by methylcholanthrene-transformed mouse BALB/3T3. Requirement for protein synthesis.
Topics: Animals; Anti-Bacterial Agents; Arachidonic Acids; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Dactinomycin; Emetine; Kinetics; Methylcholanthrene; Mice; Prostaglandins; Prostaglandins E; Prostaglandins F; Protein Biosynthesis; Tosyl Compounds; Transcription, Genetic | 1977 |
Mutants of CHO cells resistant to the protein synthesis inhibitors, cryptopleurine and tylocrebrine: genetic and biochemical evidence for common site of action of emetine, cryptopleurine, tylocrebine, and tubulosine.
Topics: Alkaloids; Animals; Anisomycin; Cells, Cultured; Cricetinae; Cross Reactions; Cycloheximide; Drug Resistance; Emetine; Female; Hybrid Cells; Indoles; Isoquinolines; Mutation; Ovary; Pactamycin; Phenanthrenes; Protein Biosynthesis; Quinolizines; Sparsomycin; Structure-Activity Relationship; Trichodermin | 1977 |
Replication of a mammalian genome: the role of de novo protein biosynthesis during S phase.
Topics: Cell Cycle; Cell Line; Chromatin; Cycloheximide; DNA Replication; Emetine; Histones; Interphase; Mutation; Nucleoproteins; Protein Biosynthesis; Temperature | 1978 |
Specific inhibition of translocation by tubulosine in eukaryotic polysomes.
Topics: Alkaloids; Cycloheximide; Emetine; Kinetics; Peptide Chain Elongation, Translational; Peptide Elongation Factors; Polyribosomes; Puromycin; Saccharomyces cerevisiae | 1976 |
Messenger ribonucleic acid metabolism in mammalian mitochondria. Isolation and characterization of polyribosomes from Ehrlich ascites mitochondria.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Fractionation; Chloramphenicol; Cycloheximide; Cytoplasm; Digitonin; Edetic Acid; Emetine; Escherichia coli; Mice; Mitochondria; Neoplasm Proteins; Polyribosomes; Puromycin; Ribonucleases | 1976 |
Prolonged inhibition of protein and glycoprotein synthesis in tumor cells treated with muconomycin A.
Topics: Anti-Bacterial Agents; Biological Transport, Active; Cell Adhesion; Cells, Cultured; Cycloheximide; Drug Synergism; Emetine; Melanoma; Neoplasm Proteins; Neoplasms, Experimental; Neuraminidase; Pactamycin; Sesquiterpenes; Sialoglycoproteins; Trichothecenes | 1977 |
Initiation and elongation of protein synthesis in growing cells: differential inhibition by cycloheximide and emetine.
Topics: Binding, Competitive; Cell Line; Cycloheximide; Emetine; Kinetics; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Polyribosomes | 1977 |
The action of metabolic inhibitors on microgametogenesis in Plasmodium yoelii nigeriensis.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites; Azaguanine; Cell Division; Colchicine; Culture Media; Cycloheximide; Dactinomycin; Emetine; Mitomycins; Plasmodium; Puromycin; Rifampin | 1977 |
In vitro synthesis of the large subunit of ribulose diphosphate carboxylase on 70 S ribosomes.
Topics: Carboxy-Lyases; Chloramphenicol; Chloroplasts; Cyanogen Bromide; Cycloheximide; Emetine; Hordeum; Kinetics; Macromolecular Substances; Molecular Weight; Peptide Fragments; Plants; Polyribosomes; Protein Biosynthesis; Ribulose-Bisphosphate Carboxylase | 1976 |
Some paradoxical effects of inhibitors of protein synthesis on protein turnover in cultured human cells.
Topics: Anisomycin; Cell Line; Culture Media; Cycloheximide; Dose-Response Relationship, Drug; Emetine; HeLa Cells; Isoquinolines; Protein Biosynthesis; Proteins; Puromycin; Valine | 1976 |
Analysis of proteins synthesized in mitochondria of cultured mammalian cells. An assessment of current approaches and problems in interpretation.
Topics: Cell Line; Chloramphenicol; Cycloheximide; Emetine; Erythromycin; Humans; Kinetics; Methionine; Mitochondria; Molecular Weight; Mycoplasma; Protein Biosynthesis | 1976 |
Shortening of the poly(A) region of mouse globin messenger RNA.
Topics: Animals; Cycloheximide; Dactinomycin; Emetine; Globins; Mice; Poly A; Protein Biosynthesis; RNA, Messenger; Spleen; Transcription, Genetic | 1976 |
Control of transfer RNA synthesis in the presence of inhibitors of protein synthesis.
Topics: Anti-Bacterial Agents; Cell Line; Cycloheximide; Emetine; Liver; Molecular Weight; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Polyribosomes; Protein Biosynthesis; Puromycin; RNA, Transfer; Transcription, Genetic; Trichodermin | 1976 |
Different susceptibility of protein synthesis to inhibitors of elongation in cell-free systems from plasma cell tumours and reticulocytes.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell-Free System; Cycloheximide; Emetine; Kinetics; Liver; Mice; Peptide Chain Elongation, Translational; Plasmacytoma; Polyribosomes; Protein Biosynthesis; Rabbits; Rats; Reticulocytes; Sparsomycin | 1976 |
The association of protein synthesis with protochlorophyllide holochrome regeneration in dark-grown barley leaves.
Topics: Chlorophyll; Chlorophyllides; Cycloheximide; Darkness; Emetine; Hordeum; Light; Molecular Weight; Plants; Protein Biosynthesis; Protochlorophyllide; Spectrophotometry | 1976 |
Surface characteristics of spleen cell-erythrocyte rosette formation in the grass frog Rana pipiens.
Topics: Animals; Anura; B-Lymphocytes; Cell Membrane; Colchicine; Cycloheximide; Cytochalasin B; Emetine; Erythrocytes; Immune Adherence Reaction; Protein Biosynthesis; Rana pipiens; Receptors, Antigen, B-Cell; Spleen; T-Lymphocytes | 1975 |
Characteristics of the prolactin stimulation of uridine metabolism in mammary gland explants.
Topics: Animals; Cycloheximide; Dactinomycin; Emetine; Female; Hydrocortisone; In Vitro Techniques; Insulin; Mammary Glands, Animal; Mice; Pregnancy; Pregnancy, Animal; Prolactin; Protein Biosynthesis; Puromycin; RNA; Sheep; Stimulation, Chemical; Uracil Nucleotides; Uridine | 1975 |
Are 50% of all cellular proteins synthesized on mitochondrial ribosomes in Crithidia luciliae?
Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Cycloheximide; Emetine; Ethidium; Eukaryota; Mitochondria; Protein Biosynthesis; Puromycin; Ribosomes; Time Factors | 1975 |
Rapid effects of insulin on uridine metabolism in mammary gland explants.
Topics: Animals; Body Water; Chromatography, Paper; Cycloheximide; Dactinomycin; Emetine; Extracellular Space; Female; In Vitro Techniques; Insulin; Inulin; Mammary Glands, Animal; Mice; Phosphates; Phosphorus Radioisotopes; Pregnancy; Protein Biosynthesis; Puromycin; RNA; Stimulation, Chemical; Time Factors; Tritium; Uridine | 1975 |
Proteins made in mitochondria of cultured animal cells.
Topics: Animals; Cell Line; Chloramphenicol; Cricetinae; Cycloheximide; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Emetine; HeLa Cells; Humans; Leucine; Methionine; Mitochondria; Protein Biosynthesis; Rabbits; Rats; Species Specificity | 1975 |
The mechanism of formation of inhibitor-induced ribosome helices in Entamoeba invadens.
Topics: Animals; Cycloheximide; Dactinomycin; Emetine; Entamoeba; Fluorides; Kinetics; Leucine; Metronidazole; Microscopy; Microscopy, Electron; Phosphates; Protein Biosynthesis; Puromycin; Ribonucleases; Ribosomes; RNA; RNA, Messenger; Sodium | 1975 |
[Proceedings: Susceptibility of endogenous mRNA translation to emetine and cycloheximide in cell free systems from plasma cell tumors, reticulocytes and liver].
Topics: Animals; Cell Line; Cell-Free System; Cycloheximide; Emetine; Liver; Plasmacytoma; Protein Biosynthesis; Rabbits; Rats; Reticulocytes; RNA, Messenger | 1975 |
Mitochondrial protein synthesis in mouse L-cells: effect of selective nicking of mitochondrial DNA.
Topics: Camptothecin; Chloramphenicol; Cycloheximide; DNA, Circular; DNA, Mitochondrial; Emetine; Ethidium; L Cells; Mitochondria; Molecular Weight; Protein Biosynthesis; Ribosomes; Transcription, Genetic | 1975 |
Hormonal control of reinitiation of meiosis in starfish. The requirement of 1-methyladenine during nuclear maturation.
Topics: Adenine; Animals; Cycloheximide; Dactinomycin; Emetine; Ethidium; Female; In Vitro Techniques; Meiosis; Oocytes; Ovum; Puromycin; Starfish | 1975 |
On the effect of inhibitors of transcription and translation on RNA and protein synthesis by isolated rat liver mitochondria.
Topics: Amanitins; Animals; Anisomycin; Cycloheximide; Cytoplasm; Emetine; Liver; Male; Mitochondria, Liver; Protein Biosynthesis; Pyrrolidines; Rats; Rifamycins; RNA; Transcription, Genetic | 1976 |
Mechanisms of cytotoxicity used by human peripheral blood T-cell subsets.
Topics: Bucladesine; CD4 Antigens; CD8 Antigens; Cholera Toxin; Cycloheximide; Cyclosporine; Cytotoxicity, Immunologic; Dactinomycin; Egtazic Acid; Emetine; Humans; Lymphocyte Activation; Mitomycin; T-Lymphocyte Subsets; Tumor Necrosis Factor-alpha | 1992 |
Regulation of P-glycoprotein gene expression in hepatocyte cultures and liver cell lines by a trans-acting transcriptional repressor.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Cells, Cultured; Cycloheximide; Drug Resistance; Emetine; Gene Expression Regulation; Humans; Liver; Membrane Glycoproteins; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Synthesis Inhibitors; Rats; Repressor Proteins; RNA, Messenger; Transcription, Genetic | 1992 |
Inhibitors of protein and RNA synthesis block the cytotoxic effects of oxygenated sterols.
Topics: Animals; Cell Division; Cycloheximide; Dactinomycin; Emetine; Hydroxycholesterols; Ketocholesterols; Kinetics; Mice; Protein Synthesis Inhibitors; Puromycin; RNA; Tumor Cells, Cultured | 1992 |
Lactoferrin release and interleukin-1, interleukin-6, and tumor necrosis factor production by human polymorphonuclear cells stimulated by various lipopolysaccharides: relationship to growth inhibition of Candida albicans.
Topics: Candida albicans; Candidiasis; Cycloheximide; Emetine; Gene Expression; Humans; Immunity, Cellular; In Vitro Techniques; Interleukin-1; Interleukin-6; Lactoferrin; Lipopolysaccharides; Neutrophils; Phagocytosis; RNA, Messenger; Tumor Necrosis Factor-alpha | 1992 |
The effects of cyclosporin A on the lysis of ovarian cancer cells by cisplatin or adriamycin.
Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Death; Cisplatin; Cycloheximide; Cyclosporine; Doxorubicin; Drug Interactions; Drug Resistance; Emetine; Female; Humans; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil | 1992 |
Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: lack of evidence for labile repressors.
Topics: Animals; Anisomycin; Blotting, Northern; Cells, Cultured; Cycloheximide; DNA-Directed RNA Polymerases; Emetine; Epidermal Growth Factor; Gene Expression Regulation; Kinetics; Mice; Mice, Inbred C3H; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Puromycin; Repressor Proteins; RNA, Messenger; Transcription, Genetic | 1992 |
Alterations of B lymphocyte Fc gamma R II expression and ligand binding capacity induced by various activators.
Topics: Animals; Antigen-Antibody Complex; Antigens, Differentiation; B-Lymphocytes; Calcimycin; Calcium; Cells, Cultured; Cycloheximide; Emetine; Female; Histocompatibility Antigens Class II; Immunoglobulin mu-Chains; In Vitro Techniques; Interleukin-4; Lymphocyte Activation; Mice; Mice, Inbred DBA; Receptors, Antigen, B-Cell; Receptors, Fc; Receptors, IgG; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Translational inhibitors cycloheximide, emetine, and puromycin inhibit cellular autophagy in mouse liver parenchymal and pancreatic acinar cells in vivo.
Topics: Animals; Autophagy; Cycloheximide; Emetine; Liver; Male; Mice; Microscopy, Electron; Pancreas; Protein Biosynthesis; Protein Synthesis Inhibitors; Puromycin; Vinblastine | 1991 |
Induction of Na(+)-K(+)-ATPase subunit mRNAs by cycloheximide in a rat liver cell line.
Topics: Animals; Anisomycin; Cell Line; Cycloheximide; Emetine; Enzyme Induction; Kinetics; Liver; Macromolecular Substances; Protein Biosynthesis; Protein Kinase C; Rats; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 1991 |
Effects of protein synthesis inhibition on PGE2 production in rabbit colonic explants cultured in vitro.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Colon; Cycloheximide; Dinoprostone; Dose-Response Relationship, Drug; Emetine; Intestinal Mucosa; Male; Organ Culture Techniques; Puromycin; Rabbits; Tritium | 1991 |
Actin mRNA localizes in the absence of protein synthesis.
Topics: Actins; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; DNA Probes; Emetine; Fibroblasts; Kinetics; Muscles; Nucleic Acid Hybridization; Protein Biosynthesis; Protein Synthesis Inhibitors; Puromycin; RNA Processing, Post-Transcriptional; RNA, Messenger; Sodium Fluoride | 1990 |
Differential sensitivity of specific and nonspecific antigen-presentation by B cells to a protein synthesis inhibitor.
Topics: Animals; Antigen-Presenting Cells; Antigens; B-Lymphocytes; Cycloheximide; Emetine; Endocytosis; Immunoglobulin M; Interleukin-2; Kinetics; Lymphocyte Activation; Mice; Ovalbumin; Receptors, Antigen, B-Cell; Trinitrobenzenes; Tumor Cells, Cultured | 1990 |
Induction of perforin and serine esterases in a murine cytotoxic T lymphocyte clone.
Topics: Animals; Biological Factors; Clone Cells; Cycloheximide; Cytokines; Dactinomycin; Emetine; Gene Expression Regulation; Granzymes; In Vitro Techniques; Interleukin-1; Interleukin-2; Membrane Glycoproteins; Membrane Proteins; Mice; Perforin; Pore Forming Cytotoxic Proteins; RNA, Messenger; Serine Endopeptidases; T-Lymphocytes, Cytotoxic | 1990 |
The effects of cycloheximide upon transcription of rRNA, 5 S RNA, and tRNA genes.
Topics: Animals; Cricetinae; Cycloheximide; DNA, Ribosomal; Emetine; Mesocricetus; Mice; Peptide Initiation Factors; RNA; RNA Polymerase I; RNA Polymerase III; RNA, Ribosomal; RNA, Transfer; Time Factors; Transcription, Genetic | 1986 |
Nucleotide sequences required for the regulation of a rat alpha 2u-globulin gene by glucocorticoids.
Topics: Alpha-Globulins; Animals; Base Sequence; Cycloheximide; Dexamethasone; Emetine; Endonucleases; Gene Expression Regulation; Glucocorticoids; Kinetics; Mutation; Rats; RNA, Messenger; Single-Strand Specific DNA and RNA Endonucleases; Transfection | 1986 |
Prespore gene expression in Dictyostelium requires concomitant protein synthesis.
Topics: Anisomycin; Cyclic AMP; Cycloheximide; Dictyostelium; Emetine; Fungal Proteins; Genes, Fungal; Kinetics; Pactamycin; Protein Synthesis Inhibitors; RNA, Messenger; Spores, Fungal; Transcription, Genetic | 1989 |
The requirement of protein synthesis for VSV inhibition of host cell RNA synthesis.
Topics: Animals; Cell Line; Cell Transformation, Viral; Cricetinae; Cycloheximide; Emetine; Kidney; Kinetics; Mutation; Pactamycin; Protein Biosynthesis; RNA; RNA, Viral; Serotyping; Transcription, Genetic; Vesicular stomatitis Indiana virus; Virion | 1985 |
Transport by the (Na+,K+) ATPase: modulation by differentiation inducers and inhibition of protein synthesis in the MDCK kidney epithelial cell line.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Cycloheximide; Dogs; Emetine; Epithelial Cells; Epithelium; Ion Channels; Kidney; Ouabain; Protein Biosynthesis; Proteins; Sodium; Sodium-Potassium-Exchanging ATPase | 1985 |
Autoregulatory control of beta-tubulin mRNA stability is linked to translation elongation.
Topics: Animals; Anisomycin; Colchicine; Cycloheximide; Emetine; Genes; Genes, Regulator; Homeostasis; Kinetics; L Cells; Mice; Peptide Chain Elongation, Translational; Polyribosomes; RNA, Messenger; Tubulin | 1989 |
Memory stages and brain asymmetry in chick learning.
Topics: Animals; Anisomycin; Brain; Brain Mapping; Chickens; Cycloheximide; Emetine; Glutamates; Glutamic Acid; Male; Memory; Ouabain | 1986 |
Enhanced transcription of c-myc in bursal lymphoma cells requires continuous protein synthesis.
Topics: Animals; Avian Leukosis; Avian Leukosis Virus; Bursa of Fabricius; Cell Line; Chick Embryo; Chickens; Chromatin; Cycloheximide; Dactinomycin; Emetine; Lymphoma; Neoplasm Proteins; Oncogenes; Repetitive Sequences, Nucleic Acid; RNA, Neoplasm; Transcription, Genetic | 1985 |
Differential responses of the dopa decarboxylase gene to 20-OH-ecdysone in Drosophila melanogaster.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Cycloheximide; DNA Restriction Enzymes; Dopa Decarboxylase; Drosophila melanogaster; Ecdysterone; Emetine; Enzyme Induction; Genes; Kinetics; Larva; Mutation; Protein Biosynthesis; Temperature; Transcription, Genetic | 1986 |
Inhibitors of protein and RNA synthesis cause a rapid block in prostaglandin production at the prostaglandin synthase step.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Cycloheximide; Dactinomycin; Emetine; In Vitro Techniques; Male; Muscles; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Puromycin; Rats; RNA, Messenger; Spleen | 1986 |
Release of arachidonate and reduction of oxygen. Independent metabolic bursts of the mouse peritoneal macrophage.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Concanavalin A; Cycloheximide; Deoxyglucose; Emetine; Female; Hydrogen Peroxide; Kinetics; Lectins; Macrophages; Mice; Mice, Inbred ICR; Oxidation-Reduction; Oxygen Consumption; Tetradecanoylphorbol Acetate; Thrombin; Wheat Germ Agglutinins | 1986 |
Cycloheximide reduces PGD2 or delta 12-PGJ2 cytotoxicity on NCG cells.
Topics: Amanitins; Cell Line; Cell Survival; Cycloheximide; Drug Interactions; Emetine; Humans; Mitomycin; Mitomycins; Neuroblastoma; Prostaglandin D2; Prostaglandins D; Puromycin | 1986 |
Modulations of functional activity in differentiated macrophages are accompanied by early and transient increase or decrease in c-fos gene transcription.
Topics: Animals; Cell Differentiation; Cells, Cultured; Cholera Toxin; Concanavalin A; Cycloheximide; Dexamethasone; Emetine; Gene Expression Regulation; Glycoproteins; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred Strains; Plasminogen Activators; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Repressor Proteins; RNA, Messenger; Transcription, Genetic; Tumor Necrosis Factor-alpha; Urokinase-Type Plasminogen Activator | 1987 |
Metabolic inhibitors and intermediate filament organization in human fibroblasts.
Topics: Acrylamide; Acrylamides; Azides; Cells, Cultured; Cycloheximide; Cytoskeleton; Dactinomycin; Emetine; Fibroblasts; Fluorescent Antibody Technique; Humans; Intermediate Filaments; Male; Microtubules; Oligomycins; Puromycin; Skin; Sodium Azide; Sodium Fluoride; Vimentin | 1988 |
Site and mechanism of growth inhibition by prostaglandins. IV. Effect of cyclopentenone prostaglandins on cell cycle progression of G1-enriched HeLa S3 cells.
Topics: Cell Cycle; Cell Line; Cycloheximide; DNA; Emetine; HeLa Cells; Humans; Kinetics; Prostaglandin D2; Prostaglandins; Prostaglandins A; Prostaglandins D; Time Factors | 1988 |
Radiation-induced recovery processes in cultured marsupial cells.
Topics: Animals; Cell Line; Cell Survival; Cycloheximide; Dose-Response Relationship, Radiation; Emetine; Kidney; Kinetics; Male; Marsupialia; Ultraviolet Rays | 1988 |
Selective synthesis and retention of 66k protein in a human neuroblastoma cell line (NCG) treated with a cytotoxic dosage of delta 12-prostaglandin J2.
Topics: Cell Division; Cell Line; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Emetine; Humans; Molecular Weight; Neoplasm Proteins; Neuroblastoma; Prostaglandin D2; Prostaglandins D | 1987 |
Effect of hCG on protein synthesis and progesterone production in the bovine luteal cells.
Topics: Animals; Cattle; Chorionic Gonadotropin; Corpus Luteum; Cycloheximide; Emetine; Female; Kinetics; Luteal Cells; Progesterone; Protein Biosynthesis; Puromycin | 1987 |
Coadministration of methylxanthines and inhibitor compounds potentiates teratogenicity in Xenopus embryos.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cycloheximide; Cytarabine; Drug Synergism; Embryo, Nonmammalian; Emetine; Fluorouracil; Hydroxyurea; Theobromine; Theophylline; Xanthines; Xenopus laevis | 1987 |
Labile proteins are necessary for T3 induction of growth hormone mRNA in normal rat pituitary and rat pituitary tumor cells.
Topics: Animals; Cycloheximide; Emetine; Growth Hormone; Male; Pituitary Gland; Pituitary Neoplasms; Puromycin; Rats; Rats, Inbred Strains; RNA, Messenger; Triiodothyronine | 1987 |
Stability of histone mRNAs is related to their location in polysomes.
Topics: Animals; Cell Line; Cycloheximide; Cytarabine; DNA Replication; Emetine; Histones; Kinetics; Polyribosomes; Protein Biosynthesis; Puromycin; Rats; RNA, Messenger; Transcription, Genetic | 1986 |
Detection of inhibitors of protein and nucleic acid synthesis using oocytes of Xenopus laevis microinjected with the herpes thymidine kinase gene.
Topics: Animals; Cycloheximide; Cytarabine; Dactinomycin; Emetine; Ethidium; Female; Genes; Hydroxyurea; Microinjections; Oocytes; Protein Biosynthesis; Puromycin; Thymidine Kinase; Transcription, Genetic; Xenopus | 1986 |
Autoregulation of thyroid iodide transport: evidence for the mediation of protein synthesis in iodide-induced suppression of iodide transport.
Topics: Animals; Biological Transport; Cats; Cattle; Cycloheximide; Emetine; Homeostasis; In Vitro Techniques; Iodides; Iodoproteins; Molecular Weight; Protein Biosynthesis; Puromycin; Sheep; Thyroid Gland | 1986 |
Induction of acquired thermotolerance in Tetrahymena thermophila: effects of protein synthesis inhibitors.
Topics: Acclimatization; Animals; Cycloheximide; Emetine; Heat-Shock Proteins; Hot Temperature; Kinetics; Nucleic Acid Hybridization; Polyribosomes; RNA, Ribosomal; Tetrahymena | 1985 |
Inhibitors of protein synthesis also inhibit lysosomal proteolysis. Studies using cystinotic fibroblasts.
Topics: Cells, Cultured; Cycloheximide; Cystine; Cystinosis; Emetine; Fibroblasts; Humans; Lysosomes; Proteins; Puromycin | 1985 |
Induction of selective phosphorylation of a fat body protein of Sarcophaga peregrina larvae by 20-hydroxyecdysone.
Topics: Adipose Tissue; Animals; Cycloheximide; Diptera; Ecdysterone; Electrophoresis, Polyacrylamide Gel; Emetine; Fat Body; Larva; Phosphorylation; Proteins | 1985 |
Regulation of rat natural killing. I. Inhibition of cytolysis and activation by protein synthesis inhibitors.
Topics: Animals; Cycloheximide; Cytotoxicity, Immunologic; Emetine; Female; In Vitro Techniques; Killer Cells, Natural; Neoplasms, Experimental; Protein Biosynthesis; Rats; Rats, Inbred WF | 1985 |
The synthetic and minimal culture requirements for evagination of imaginal discs of Drosophila melanogaster in vitro.
Topics: Amino Acids; Animals; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; Drosophila melanogaster; Ecdysone; Emetine; Extremities; Glucose; In Vitro Techniques; Leucine; Metamorphosis, Biological; Mycotoxins; Puromycin; RNA; Thymidine; Tritium; Wings, Animal | 1973 |
Inhibitors of protein biosynthesis. V. Effects of emetine on protein and nucleic acid biosynthesis in HeLa cells.
Topics: Carbon Isotopes; Centrifugation, Density Gradient; Cycloheximide; DNA; DNA Nucleotidyltransferases; Emetine; HeLa Cells; Leucine; Nucleic Acids; Poliovirus; Protein Biosynthesis; Puromycin; Ribosomes; RNA; RNA, Viral; Thymidine; Thymidine Kinase; Tritium; Uridine | 1968 |
Accentuation of interferon production by metabolic inhibitors and its dependence on protein synthesis.
Topics: Animals; Carbon Isotopes; Cell Survival; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Drug Synergism; Emetine; Fluorine; Interferons; Kidney; Phenylalanine; Poly I-C; Protein Biosynthesis; Protein Hydrolysates; Puromycin; Rabbits; Vesicular stomatitis Indiana virus | 1971 |
Inhibition of protein synthesis: a mechanism of amebicide action of emetine and other structurally related compounds.
Topics: Alkaloids; Amebicides; Animals; Cycloheximide; Emetine; Entamoeba histolytica; Penicillin Resistance; Penicillins; Protein Biosynthesis; Proteins; Puromycin; Rabbits; Reticulocytes | 1973 |
Mechanism of cytolysis by thymus-derived lymphocytes. Implications in tumor immunity.
Topics: Animals; Colchicine; Cyclic AMP; Cycloheximide; Cytochalasin B; Edetic Acid; Emetine; Immunity, Cellular; Immunization; Mast-Cell Sarcoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms; Neoplasms, Experimental; Spleen; T-Lymphocytes | 1974 |
Mitochondrial protein synthesis: inhibition by emetine hydrochloride.
Topics: Alkaloids; Animals; Anti-Bacterial Agents; Antimetabolites; Bacterial Proteins; Chloramphenicol; Cycloheximide; Emetine; Ipecac; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Mitochondria, Liver; Oxalates; Protein Biosynthesis; Proteins; Pyrrolidines; Structure-Activity Relationship | 1971 |
Production of membrane whorls in rat liver by some inhibitors of protein synthesis.
Topics: Animals; Cell Membrane; Chloramphenicol; Choline; Cycloheximide; Cytochrome Reductases; Emetine; Endoplasmic Reticulum; Fasting; Histocytochemistry; Leucine; Liver; Male; Microscopy, Electron; Protein Biosynthesis; Puromycin; Time Factors; Tritium | 1974 |
Emetine and macromolecular biosynthesis in mammalian cells.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Child; Child, Preschool; Cycloheximide; Dactinomycin; Emetine; Glucosamine; Glycoproteins; Humans; Kinetics; Leucine; Lymphocytes; Mice; Neoplasm Proteins; Organ Specificity; Palatine Tonsil; Protein Biosynthesis; Puromycin; RNA; RNA, Neoplasm; Species Specificity; Time Factors; Transcription, Genetic; Tritium; Uridine | 1974 |
A correlation between the polysome pattern and the synthesis of transfer RNA in Chang's liver cells.
Topics: Amino Acids; Carbon Radioisotopes; Cell Fractionation; Cells, Cultured; Centrifugation, Density Gradient; Cycloheximide; Emetine; Glutamine; Kinetics; Liver; Polyribosomes; Puromycin; RNA, Ribosomal; RNA, Transfer; Uridine | 1974 |
[Inhibitors of protein synthesis and hepatic steatosis: difference between cycloheximide, emetine and N-dimethylnitrosamine].
Topics: Adrenal Glands; Amino Acids; Animals; Blood Proteins; Cycloheximide; Dimethylnitrosamine; Emetine; Fatty Liver; Lipid Metabolism; Lipoproteins; Liver; Male; Nitrosamines; Proteins; Rats; Triglycerides | 1974 |
The prevention by inhibitors of brain proptein synthesis of the hyperactivity and hyperpyrexia produced in rats by monoamine oxidase inhibition and the administration of L-tryptophan or 5-methoxy-N,N-dimethyltryptamine.
Topics: Amphetamine; Animals; Brain; Carbon Isotopes; Cycloheximide; Emetine; Fever; Hallucinogens; Humans; Hyperkinesis; Male; Methyl Ethers; N,N-Dimethyltryptamine; Nerve Tissue Proteins; Puromycin; Rats; Serotonin; Time Factors; Tranylcypromine; Tryptophan | 1972 |
Atypical pattern of utilization of amino acids for mitochondrial protein synthesis in HeLa cells.
Topics: Amino Acids; Arginine; Chloramphenicol; Cycloheximide; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Emetine; Endoplasmic Reticulum; Female; Glutamine; HeLa Cells; Humans; Leucine; Lysine; Methionine; Mitochondria; Neoplasm Proteins; Phenylalanine; Polyribosomes; Serine; Threonine; Tritium; Tryptophan | 1973 |
A method for obtaining antibiotic-sensitive mutants in Saccharomyces cerevisiae.
Topics: Anti-Bacterial Agents; Cell Survival; Cycloheximide; Drug Resistance, Microbial; Emetine; Methods; Mutation; Saccharomyces; Saccharomyces cerevisiae; Temperature; Trimethoprim | 1972 |
Effects of emetine and cycloheximide on mitochondrial protein synthesis in different systems.
Topics: Animals; Cycloheximide; Emetine; Female; Humans; In Vitro Techniques; Mice; Microscopy, Phase-Contrast; Mitochondria; Mitochondria, Liver; Protein Biosynthesis; Uterine Cervical Neoplasms; Uterus | 1972 |
Inhibitors of protein synthesis in eukaryotes: tools in cell research.
Topics: Alkaloids; Animals; Anti-Bacterial Agents; Bacterial Proteins; Cell-Free System; Coloring Agents; Cycloheximide; Emetine; Escherichia coli; Globins; HeLa Cells; Isoquinolines; Neoplasm Proteins; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Polyribosomes; Protein Biosynthesis; Puromycin; Rabbits; Reticulocytes; RNA, Messenger; RNA, Transfer; Sulfhydryl Compounds | 1973 |
The elongation steps in protein synthesis by eukaryotic ribosomes: effects of antibiotics.
Topics: Anti-Bacterial Agents; Carbon Radioisotopes; Centrifugation, Density Gradient; Cycloheximide; Emetine; Escherichia coli; Fungal Proteins; Fusidic Acid; Humans; Leucine; Methods; Palatine Tonsil; Peptide Chain Elongation, Translational; Peptide Elongation Factors; Phenylalanine; Protein Biosynthesis; Puromycin; Ribosomes; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Tritium | 1974 |
Expression of the mitochondrial genome in HeLa cells. X. Properties of mitochondrial polysomes.
Topics: Amino Acids; Centrifugation, Density Gradient; Chromosomes; Cycloheximide; Edetic Acid; Emetine; Endoplasmic Reticulum; Ethidium; HeLa Cells; Humans; Mitochondria; Protein Biosynthesis; Ribonucleases; Ribosomes; Tritium | 1972 |
Ciliary proteins and cytodifferentiation in Stentor coeruleus.
Topics: Chloramphenicol; Cilia; Ciliophora; Colchicine; Cycloheximide; Emetine; Protein Biosynthesis | 1972 |
Acceleration of gluconeogenesis following inhibition of protein synthesis in Tetrahymena pyriformis.
Topics: Acetates; Amino Acids; Animals; Anti-Bacterial Agents; Carbon Isotopes; Cell Count; Culture Media; Cycloheximide; Emetine; Gluconeogenesis; Glycogen; Hydrolysis; Kinetics; Phospholipids; Plant Proteins; Polyribosomes; Protein Biosynthesis; Tetrahymena pyriformis; Triglycerides | 1973 |
Effect of cycloheximide and emitine on 14 C-amino acids incorporation by different subcellular fractions from rat liver.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Carbon Isotopes; Cycloheximide; Emetine; In Vitro Techniques; Liver; Microsomes, Liver; Mitochondria, Liver; Protein Biosynthesis; Rats; Subcellular Fractions | 1972 |
Prevention of induced autophagocytosis by the protein-synthesis inhibitor emetine. Short communication.
Topics: Animals; Cycloheximide; Emetine; Endoplasmic Reticulum; Epithelial Cells; Epithelium; Male; Mice; Pancreas; Phagocytosis; Protein Biosynthesis; Proteins; Ribosomes; Seminal Vesicles | 1973 |
Translational control of immunoglobulin synthesis. I. Repression of heavy chain synthesis.
Topics: Animals; Antibody-Producing Cells; Bone Marrow; Bone Marrow Cells; Cold Temperature; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Emetine; Immunoglobulin Fragments; Immunoglobulin G; In Vitro Techniques; Kinetics; Lymphocytes; Methionine; Mice; Myeloma Proteins; Peptide Chain Elongation, Translational; Protein Biosynthesis; Sulfur Isotopes | 1973 |
A sensitive in vitro protein synthesizing system from Ehrlich ascites mitochondria.
Topics: Animals; Carcinoma, Ehrlich Tumor; Centrifugation, Density Gradient; Chloramphenicol; Chromatography, Gel; Cycloheximide; Cytoplasm; Digitonin; Electrophoresis, Polyacrylamide Gel; Emetine; Mice; Mitochondria; Neoplasm Proteins; Phenylalanine; Protein Biosynthesis; Puromycin; Ribosomes; RNA, Ribosomal; RNA, Transfer; Spectrophotometry, Ultraviolet; Streptomycin; Tritium | 1974 |
On the mechanism of adaptation to protein synthesis inhibitors by Tetrahymena. Facilitation, cross adaptation, and resensitization.
Topics: Adaptation, Physiological; Cell Count; Cell Division; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Emetine; Kinetics; Tetrahymena | 1974 |
Translational control of antibody synthesis. Control of light chain production.
Topics: Animals; Antibody Formation; Carbon Radioisotopes; Cell Division; Cell Line; Centrifugation, Density Gradient; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Emetine; Immunoglobulin Fragments; Mice; Peptide Chain Elongation, Translational; Plasmacytoma; Polyribosomes; Precipitin Tests; Protein Biosynthesis; Ribosomes; RNA, Messenger; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Time Factors | 1974 |
Protein synthesis in a cell-free preparation from Tetrahymena pyriformis GL.
Topics: Adenosine Triphosphate; Amino Acids; Ammonium Chloride; Animals; Carbon Isotopes; Chloramphenicol; Cycloheximide; Emetine; Erythromycin; Guanosine Triphosphate; Kinetics; Magnesium; Potassium Chloride; Protein Biosynthesis; Puromycin; Sodium Chloride; Streptomycin; Subcellular Fractions; Tetracycline; Tetrahymena pyriformis | 1971 |
Turnover of molecules which maintain the normal surfaces of contact-inhibited cells.
Topics: Agglutination; Animals; Antibiotics, Antineoplastic; Cell Division; Cells, Cultured; Chick Embryo; Concanavalin A; Contact Inhibition; Cycloheximide; Emetine; Fibroblasts; Lectins; Time Factors | 1972 |
The differential sensitivity of free and membrane-bound polyribosomes to inhibitors of protein synthesis.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Centrifugation, Density Gradient; Chloramphenicol; Cyclohexanecarboxylic Acids; Cycloheximide; Emetine; Fusidic Acid; Leucine; Liver; Male; Membranes; Protein Biosynthesis; Puromycin; Rats; Ribosomes; Tritium | 1972 |
A role for brain protein in the process by which brain serotonin and certain other indolealkylamines produce behaviourally excitant effects in the rat.
Topics: Animals; Behavior, Animal; Brain; Cycloheximide; Emetine; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Puromycin; Rats; Serotonin; Tranylcypromine; Tryptamines; Tryptophan | 1972 |
The release of interferon: an active process inhibited by p-hydroxymercuribenzoate.
Topics: Acetamides; Animals; Cells, Cultured; Cyanides; Cycloheximide; Dithiothreitol; Emetine; Ethylmaleimide; Fluorides; Hydroxymercuribenzoates; Interferons; Iodoacetates; Kidney; Kinetics; Poly I-C; Protein Biosynthesis; Rabbits | 1972 |
The effect of inhibitors of protein synthesis to inhibit brain protein synthesis and prevent the hyperactivity and hyperpyrexia in rats produced by inhibition of monoamine oxidase and the administration of L-tryptophan or 5-methoxy-NN-dimethyltryptamine.
Topics: Animals; Brain; Cycloheximide; Emetine; Mice; Nerve Tissue Proteins; Tryptamines; Tryptophan | 1972 |
Initiation of hemoglobin synthesis. Specific inhibition by antibiotics and bacteriophage ribonucleic acid.
Topics: Antibiotics, Antineoplastic; Carbon Isotopes; Centrifugation, Density Gradient; Coliphages; Cyclohexanecarboxylic Acids; Cycloheximide; Depression, Chemical; Emetine; Hemoglobins; Methionine; Peptide Biosynthesis; Peptide Chain Initiation, Translational; Phosphorus Isotopes; Reticulocytes; Ribosomes; RNA, Transfer; RNA, Viral; Sulfur Isotopes | 1971 |
Effect of emetine on ribonucleic acid biosynthesis in HeLa cells.
Topics: Cycloheximide; Dactinomycin; Electrophoresis; Emetine; HeLa Cells; In Vitro Techniques; RNA, Neoplasm; RNA, Ribosomal; Tritium; Uridine | 1971 |
Proteins coded by mitochondrial DNA of mammalian cells.
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Chloramphenicol; Cricetinae; Cycloheximide; Cytoplasm; DNA; Electrophoresis; Emetine; Genetic Code; Hydrogen-Ion Concentration; Kidney; Mitochondria, Liver; Molecular Weight; Peptide Biosynthesis; Phenanthridines; Protein Biosynthesis; Rats; Ribosomes | 1971 |
Applications of the mouse foot edema test in evaluation of anti-cholera drugs.
Topics: Animals; Anti-Infective Agents; Aspirin; Chloramphenicol; Cholera; Cycloheximide; Dactinomycin; Diuretics; Edema; Emetine; Enterotoxins; Ethacrynic Acid; Fasting; Furosemide; Indomethacin; Iproniazid; Mercaptopurine; Mice; Models, Biological; Phenylbutazone; Protein Biosynthesis; Puromycin; Time Factors; Triamcinolone | 1971 |
Properties distinguishing mitochondrial and synaptosomal protein synthesis.
Topics: Animals; Brain; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Chloroquine; Cycloheximide; Depression, Chemical; Drug Antagonism; Emetine; Leucine; Mice; Mitochondria; Nerve Endings; Nerve Tissue Proteins; Synaptic Vesicles; Synaptosomes | 1971 |
Alpha and beta globin messenger ribonucleic acid. Different amounts and rates of initiation of translation.
Topics: Animals; Anti-Bacterial Agents; Centrifugation, Density Gradient; Cycloheximide; Depression, Chemical; Emetine; Fusidic Acid; Globins; Methionine; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Chain Termination, Translational; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; RNA, Transfer; Sulfur Isotopes | 1971 |
Mitochondrial protein synthesis: resistance to emetine and response to RNA synthesis inhibitors.
Topics: Adenine; Chloramphenicol; Cycloheximide; Dactinomycin; Emetine; HeLa Cells; Leucine; Mitochondria; Nucleosides; Phenanthridines; Protein Biosynthesis; Ribonucleases; RNA; Tritium | 1970 |
Regulation of iron entry into reticulocytes. II. Relationship between hemoglobin synthesis and entry of iron into reticulocytes.
Topics: Animals; Biological Transport; Carbon Isotopes; Cell Membrane; Chloramphenicol; Cycloheximide; Emetine; Fluorides; Globins; Glycine; Heme; Hemoglobins; In Vitro Techniques; Iron; Iron Isotopes; Isoniazid; Penicillamine; Puromycin; Pyridoxal Phosphate; Rabbits; Reticulocytes; Tryptamines | 1971 |
Observations on the mechanism of emetine poisoning of myocardial tissue.
Topics: Animals; Cycloheximide; Emetine; Heart; In Vitro Techniques; Leucine; Muscle Proteins; Myocardium; Protein Biosynthesis; Rats | 1968 |
Enhanced protein synthesis at the liver microsomal level in emetine-pretreated rats.
Topics: Amino Acids; Animals; Carbon Isotopes; Cycloheximide; Emetine; Female; Leucine; Liver; Magnesium; Microsomes; Phenylalanine; Protein Biosynthesis; Rats | 1968 |
Linked induction of glycosidases in Stachybotrys atra.
Topics: Cycloheximide; Emetine; Enzyme Induction; Esterases; Galactose; Galactosidases; Genes, Regulator; Genetic Code; Glucosidases; Glycoside Hydrolases; Glycosides; Hydrogen-Ion Concentration; Lactose; Mitosporic Fungi; Phenols; Time Factors; Ultrasonics | 1968 |
Mechanism of cycloheximide inhibition of protein synthesis in a cell-free system prepared from rat liver.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Carbon Isotopes; Cell-Free System; Cycloheximide; Depression, Chemical; Emetine; Glutathione; In Vitro Techniques; Leucine; Liver; Methods; Peptide Biosynthesis; Protein Biosynthesis; Rats; Ribosomes; RNA, Transfer; Stimulation, Chemical; Sulfhydryl Compounds; Transferases; Ultracentrifugation | 1969 |
Schistosoma mansoni: comparision of the effects of cycloheximide and emetine on protein synthesis in adult worms.
Topics: Animals; Cycloheximide; Emetine; Female; Male; Protein Biosynthesis; Schistosoma mansoni; Sex Factors | 1980 |
Regulation of tyrosine aminotransferase mRNA in HTC cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Emetine; Enzyme Induction; Kinetics; Liver Neoplasms; Protein Biosynthesis; Rats; RNA, Messenger; Tyrosine Transaminase | 1980 |
Effects of metabolic inhibitors on spontaneous and interferon-boosted human natural killer cell activity.
Topics: Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; DNA; Emetine; Humans; Interferons; Mitomycins; Pactamycin; Protein Biosynthesis; Puromycin; RNA; Time Factors | 1980 |
Studies on differentiation without cleavage in Chaetopterus variopedatus: requirements for nucleic acid and protein synthesis.
Topics: Animals; Cell Differentiation; Cycloheximide; Dactinomycin; DNA; Dose-Response Relationship, Drug; Emetine; Female; Hydroxyurea; Polychaeta; Protein Biosynthesis; Puromycin; RNA; Time Factors; Zygote | 1980 |
Modification of transcriptional activity induced by protein synthesis inhibitors in salivary gland cells of Chironomus thummi.
Topics: Animals; Anisomycin; Biological Transport; Chironomidae; Cycloheximide; DNA-Directed RNA Polymerases; Emetine; Molecular Weight; Pyrrolidines; RNA; Salivary Glands; Transcription, Genetic; Uridine | 1981 |
Selective reduction of forskolin-stimulated cyclic AMP accumulation by inhibitors of protein synthesis.
Topics: Animals; Astrocytoma; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dichlororibofuranosylbenzimidazole; Diterpenes; Emetine; Isoproterenol; Protein Biosynthesis; Rats; RNA | 1983 |
Inhibition of Balbiani ring transcription following differential arrest of Balbiani ring-coded translation.
Topics: Amino Acids; Animals; Chironomidae; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Emetine; Larva; Molecular Weight; Nucleosides; Protein Biosynthesis; Proteins; RNA; Salivary Glands; Transcription, Genetic | 1983 |
Specificity of protein synthesis inhibitors in the inhibition of encephalomyocarditis virus replication.
Topics: Animals; Anisomycin; Cycloheximide; Emetine; Encephalomyocarditis virus; Harringtonines; Hypertonic Solutions; L Cells; Mice; Pactamycin; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Viral Proteins; Virus Replication | 1980 |
Expression of early and late simian virus 40 transcripts in the absence of protein synthesis.
Topics: Animals; Base Sequence; Cell Line; Cycloheximide; Cytoplasm; Emetine; Haplorhini; RNA, Messenger; RNA, Viral; Simian virus 40; Transcription, Genetic; Viral Proteins | 1980 |
5'-Nucleotidase activity in liver homogenates of rats treated with CCl4, colchicine, cycloheximide, emetine, ethanol, ethionine and 5-fluorotryptophan.
Topics: Animals; Carbon Tetrachloride Poisoning; Colchicine; Cycloheximide; Emetine; Ethanol; Ethionine; Female; Liver; Male; Nucleotidases; Rats; Sex Factors; Tryptophan | 1980 |
Selective inhibition of calcium-stimulated cation-induced pinocytosis by starvation and inhibitors of protein synthesis in Amoeba proteus.
Topics: Amoeba; Animals; Calcium; Culture Media; Cycloheximide; Emetine; Membrane Potentials; Pinocytosis; Potassium; Protein Biosynthesis; Puromycin; Sodium; Subtilisins | 1984 |
Dissociation of RNA synthesis from the calcium requirement for serum-increased ornithine decarboxylase activity in rat glioma cells.
Topics: Animals; Calcium; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Egtazic Acid; Emetine; Glioma; Kinetics; Ornithine Decarboxylase; Rats; RNA, Neoplasm; Transcription, Genetic | 1984 |
Potentiative interactions between caffeine and various teratogenic agents.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Caffeine; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Emetine; Female; Fetal Death; Floxuridine; Hydroxyurea; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
Activation of the capacity for sodium-induced pinocytosis in Amoeba proteus.
Topics: Action Potentials; Amoeba; Animals; Calcium; Culture Media; Cycloheximide; Electric Conductivity; Emetine; Pinocytosis; Sodium | 1984 |
Blockade of long-term potentiation in rat hippocampal CA1 region by inhibitors of protein synthesis.
Topics: Action Potentials; Animals; Cycloheximide; Electrophysiology; Emetine; Hippocampus; Male; Protein Biosynthesis; Puromycin; Rats; Rats, Inbred Strains | 1984 |
Anti-idiotypic regulation of IgA expression in myeloma cells.
Topics: Animals; Antibodies, Anti-Idiotypic; Cell Survival; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Immunologic; Emetine; Immunoglobulin A; Immunoglobulin Idiotypes; Mice; Mice, Inbred BALB C; Plasmacytoma; Receptors, Antigen, B-Cell | 1983 |
Effects of various agents on the in vivo "lipoperoxide" content of rat liver and kidney and on the "lipoperoxide" and lipid content of liver slices.
Topics: Animals; Cycloheximide; Emetine; Female; Kidney; Lipid Peroxides; Lipids; Liver; Rats; Rats, Inbred Strains | 1983 |
Balance of ATP consumption of reticulocytes.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Cycloheximide; Emetine; Kinetics; Lanthanum; Ouabain; Oxygen Consumption; Rabbits; Reticulocytes | 1983 |
Role of protein synthesis in the activation of cytotoxic mouse macrophages by lymphokines.
Topics: Animals; Cycloheximide; Cytotoxicity, Immunologic; Emetine; Female; Lymphokines; Lymphoma; Macrophage Activation; Mice; Mice, Inbred Strains; Pactamycin; Protein Biosynthesis; Proteins; Puromycin | 1984 |
Arginine activation of N-acetylglutamate synthetase in mouse liver. Enhancement of the sensitivity in vivo by parenteral treatment with inhibitors of nucleic acid and protein synthesis.
Topics: Acetyltransferases; Amino Acids; Amino-Acid N-Acetyltransferase; Animals; Arginine; Aurintricarboxylic Acid; Cycloheximide; Dose-Response Relationship, Drug; Emetine; Enzyme Activation; Liver; Mice; Nucleic Acids; Protein Biosynthesis; Puromycin | 1983 |
Characterization of macrophage- and granulocyte-inducing proteins for normal and leukemic myeloid cells produced by the Krebs ascites tumor.
Topics: Animals; Biological Assay; Bone Marrow; Carbohydrates; Carcinoma, Krebs 2; Colony-Stimulating Factors; Cycloheximide; Dactinomycin; Drug Stability; Emetine; Granulocytes; Leukemia, Experimental; Leukemia, Myeloid; Macrophages; Mice; Mice, Inbred ICR; Neoplasm Proteins; Peptide Hydrolases; Protease Inhibitors | 1981 |
Autophagocytosis: freeze-fracture morphology, effects of vinblastine and influence of transcriptional and translational inhibitors.
Topics: Animals; Autophagy; Azaguanine; Cycloheximide; Dactinomycin; Emetine; Endoplasmic Reticulum; Freeze Fracturing; Intracellular Membranes; Lepidoptera; Mice; Organoids; Phagocytosis; Protein Biosynthesis; Puromycin; Rats; Transcription, Genetic; Vacuoles; Vinblastine | 1982 |
Colchicine resistance in human cell lines. Pleiotropic phenotype and decreased membrane permeability.
Topics: Cell Line; Colchicine; Cross Reactions; Cycloheximide; Daunorubicin; Drug Resistance; Emetine; Humans; Lidocaine; Phenotype; Skin; Vinblastine; Vincristine | 1982 |
Protection with cycloheximide or emetine against pulmonary edema induced by ozone or nitrogen dioxide.
Topics: Animals; Cycloheximide; Emetine; Male; Nitrogen Dioxide; Ozone; Premedication; Pulmonary Edema; Rats; Rats, Inbred Strains | 1982 |
Resistance to inhibitors of mammalian cell protein synthesis induced by preincubation in hypertonic growth medium.
Topics: Animals; Culture Media; Cycloheximide; Emetine; Kinetics; L Cells; Mice; Osmolar Concentration; Peptide Chain Elongation, Translational; Protein Biosynthesis; Sodium Chloride | 1982 |
Inhibitors of protein synthesis on 80S ribosomes phase shift the Gonyaulax clock.
Topics: Animals; Anisomycin; Anti-Bacterial Agents; Circadian Rhythm; Cycloheximide; Dinoflagellida; Emetine; Piperidones; Protein Biosynthesis; Ribosomes | 1982 |
The response of rat hind limbs to X irradiation: a possible role for protein synthesis.
Topics: Animals; Chloramphenicol; Cycloheximide; Emetine; Hindlimb; Injections, Intraperitoneal; Male; Protein Biosynthesis; Proteins; Radiation-Protective Agents; Rats; Skin; Time Factors | 1981 |
Influence of protein synthesis inhibitors on neutral red-induced autophagocytosis in chicken pancreatic acinar cells.
Topics: Animals; Autophagy; Chickens; Cycloheximide; Emetine; Male; Microscopy, Electron; Neutral Red; Pancreas; Phagocytosis; Phenazines | 1980 |
Evidence indicating that inactivation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by low density lipoprotein or by 25-hydroxycholesterol requires mediator protein(s) with rapid turnover rate.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Cycloheximide; Emetine; Female; Half-Life; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Ovary; Puromycin | 1981 |
Active tumor cell resistance to human natural killer lymphocyte attack.
Topics: Cell Line; Cycloheximide; Emetine; Humans; Killer Cells, Natural; Leukemia; Neoplasms; Protein Biosynthesis; Puromycin; Time Factors; Urinary Bladder Neoplasms | 1981 |
Protective effect of cycloheximide on the response of rat hind limbs to X irradiation.
Topics: Animals; Cell Cycle; Cycloheximide; Emetine; Hindlimb; Male; Premedication; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Rats, Inbred Strains; Skin; Time Factors | 1981 |
Suppression of cytidylate biosynthesis by protein synthesis antagonists.
Topics: Animals; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Emetine; HeLa Cells; Liver Neoplasms, Experimental; Piperidones; Puromycin; Pyrimidine Nucleotides; Rats; RNA, Neoplasm; Uridine | 1980 |
Transcriptional regulation of PS-IAA4/5 and PS-IAA6 early gene expression by indoleacetic acid and protein synthesis inhibitors in pea (Pisum sativum).
Topics: Anisomycin; Base Sequence; Cycloheximide; DNA, Plant; Emetine; Gene Expression Regulation, Plant; Genes, Plant; Indoleacetic Acids; Kinetics; Molecular Sequence Data; Pisum sativum; Plants, Genetically Modified; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Plant; Transcriptional Activation | 1995 |
Inhibitors of protein and RNA synthesis block the cytotoxic effects of non-steroidal antiestrogens.
Topics: Animals; Cell Line; Cell Survival; Clomiphene; Cycloheximide; Cytotoxins; Emetine; Mice; Protein Biosynthesis; Puromycin; RNA; Tamoxifen | 1995 |
Effects of antioxidants on the anti-proliferation induced by protein synthesis inhibitors in human brain tumor cells.
Topics: Anisomycin; Astrocytoma; Brain Neoplasms; Cell Division; Cycloheximide; Drug Screening Assays, Antitumor; Emetine; Humans; Neuroblastoma; Protein Synthesis Inhibitors; Puromycin; Tumor Cells, Cultured | 1995 |
Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis.
Topics: Animals; Apoptosis; Calcium-Transporting ATPases; Cell Survival; Cells, Cultured; Cycloheximide; DNA; Emetine; Ionomycin; Male; Methylprednisolone; Protein Biosynthesis; Protein Synthesis Inhibitors; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; T-Lymphocytes; Terpenes; Thapsigargin; Thymus Gland | 1995 |
Formation of high molecular mass DNA fragments is a marker of apoptosis in the human leukaemic cell line, U937.
Topics: Apoptosis; Biomarkers; Camptothecin; Cycloheximide; Dactinomycin; DNA Damage; DNA, Neoplasm; Emetine; Flow Cytometry; Humans; Leukemia, Promyelocytic, Acute; Molecular Weight; Neoplasm Proteins; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1994 |
A labile transcriptional repressor modulates endotoxin tolerance.
Topics: Blotting, Northern; Cell Line; Cell Nucleus; Cycloheximide; Dose-Response Relationship, Drug; Drug Tolerance; Emetine; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; Puromycin; Repressor Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1994 |
The myogenin gene is activated during myocyte differentiation by pre-existing, not newly synthesized transcription factor MEF-2.
Topics: Animals; Base Sequence; Cell Differentiation; Cells, Cultured; Chickens; Cycloheximide; DNA Primers; DNA-Binding Proteins; Emetine; Enhancer Elements, Genetic; Fibroblasts; Gene Expression; Helix-Loop-Helix Motifs; In Vitro Techniques; MEF2 Transcription Factors; Mice; Molecular Sequence Data; Muscles; MyoD Protein; Myogenic Regulatory Factors; Myogenin; Promoter Regions, Genetic; RNA, Messenger; Structure-Activity Relationship; Transcription Factors | 1994 |
Oncogene expression in thymocytes after emetine treatment of mice.
Topics: Animals; Cell Differentiation; Cells, Cultured; Cycloheximide; DNA; DNA Replication; Emetine; Gene Expression; Genes, fos; Genes, myc; Immunosuppressive Agents; Kinetics; Male; Mice; Oncogenes; Proto-Oncogenes; Puromycin; RNA, Messenger; T-Lymphocytes; Thymus Gland; Time Factors; Transcription, Genetic | 1993 |
Protein turnover during metabolic arrest in turtle hepatocytes: role and energy dependence of proteolysis.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Cycloheximide; Emetine; Energy Metabolism; Female; Half-Life; Hypoxia; Liver; Peptide Hydrolases; Protease Inhibitors; Proteins; Turtles | 1994 |
Alteration of the phosphorylation state of p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Correlation with decreased H1 kinase activity.
Topics: Amino Acid Sequence; Aphidicolin; Breast Neoplasms; CDC2 Protein Kinase; Cyclins; Cycloheximide; Down-Regulation; Emetine; Enzyme Activation; Flavonoids; Humans; Maturation-Promoting Factor; Mitosis; Molecular Sequence Data; Phosphorylation; Piperidines; Precipitin Tests; S Phase; Tumor Cells, Cultured | 1993 |
Cycloheximide induces the alpha 1B adrenergic receptor gene by activation of transcription in DDT1 MF-2 smooth muscle cells.
Topics: Animals; Anisomycin; Cells, Cultured; Cricetinae; Cycloheximide; Emetine; Muscle, Smooth; Receptors, Adrenergic, alpha-1; RNA, Messenger; Transcription, Genetic | 1993 |
Abrogation of wild-type p53 mediated growth-inhibition by nuclear exclusion.
Topics: Animals; Antigens, Polyomavirus Transforming; Base Sequence; Cell Division; Cell Line, Transformed; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Cytoplasm; Emetine; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, p53; Genes, ras; Molecular Sequence Data; Mutation; Nuclear Proteins; Pheochromocytoma; Phosphorylation; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Temperature; Transfection; Transformation, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation | 1996 |
Modification of the alternative splicing process of testosterone-repressed prostate message-2 (TRPM-2) gene by protein synthesis inhibitors and heat shock treatment.
Topics: Alternative Splicing; Animals; Anisomycin; Apoptosis; Base Sequence; Blotting, Northern; Clusterin; Cycloheximide; Dactinomycin; Emetine; Glycoproteins; Hot Temperature; Liver; Male; Molecular Chaperones; Molecular Sequence Data; Polymerase Chain Reaction; Protein Synthesis Inhibitors; Rats; Rats, Inbred Strains; RNA, Messenger; Tissue Distribution | 1996 |
Preincubation with protein synthesis inhibitors protects cortical neurons against oxygen-glucose deprivation-induced death.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; Dizocilpine Maleate; Emetine; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hypoxia, Brain; Mice; Nerve Tissue Proteins; Neuroglia; Neurons; Protein Synthesis Inhibitors | 1996 |
Enhancement and repression of cyanide-insensitive respiration in Aspergillus niger.
Topics: Antimycin A; Aspergillus niger; Biological Transport; Cell Respiration; Cyanides; Cycloheximide; Dactinomycin; Emetine; Hydrazones; Mitochondria; Oxidoreductases; Puromycin; Salicylamides | 1996 |
Cycloheximide enhances ACTH-receptor mRNA through transcriptional and post-transcriptional mechanisms in bovine adrenocortical cells.
Topics: Adrenocorticotropic Hormone; Animals; Cattle; Cells, Cultured; Cycloheximide; Emetine; Protein Synthesis Inhibitors; Puromycin; Receptors, Corticotropin; RNA, Messenger; Time Factors; Transcription, Genetic; Zona Fasciculata | 1996 |
Expression of urokinase-type plasminogen activator, its receptor and type-1 plasminogen activator inhibitor is differently regulated by inhibitors of protein synthesis in human cancer cell lines.
Topics: Anisomycin; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Emetine; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Lung Neoplasms; Protein Synthesis Inhibitors; Puromycin; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Rhabdomyosarcoma; RNA, Messenger; RNA, Neoplasm; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1996 |
Activation of JNK/SAPK pathway is not directly inhibitory for cell cycle progression in NIH3T3 cells.
Topics: 3T3 Cells; Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cycloheximide; DNA; DNA-Binding Proteins; E2F Transcription Factors; Emetine; Enzyme Activation; GADD45 Proteins; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Protein Kinases; Protein Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Retinoblastoma-Binding Protein 1; RNA, Messenger; Transcription Factor DP1; Transcription Factors | 1996 |
Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide.
Topics: Animals; Apoptosis; Aurintricarboxylic Acid; Calcium; Cell Death; Cell Line; Cell Nucleus; Cycloheximide; Emetine; Gene Expression; Genes, bcl-2; Hydrogen Peroxide; Mice; ortho-Aminobenzoates; Oxidants; Protein Synthesis Inhibitors | 1997 |
Induction of apoptosis and changes in nuclear G-actin are mediated by different pathways: the effect of inhibitors of protein and RNA synthesis in isolated rat hepatocytes.
Topics: Actins; Animals; Apoptosis; Caspases; Cell Nucleus; Cell Survival; Cycloheximide; Dactinomycin; Emetine; Liver; Male; Necrosis; Protein Synthesis Inhibitors; Puromycin; Rats; Rats, Wistar; RNA | 1999 |
The yeast multidrug resistance pump, Pdr5p, confers reduced drug resistance in erg mutants of Saccharomyces cerevisiae.
Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Cell Membrane; Cycloheximide; Drug Resistance, Microbial; Drug Resistance, Multiple; Emetine; Ergosterol; Estradiol; Fungal Proteins; Membrane Fluidity; Membrane Proteins; Microbial Sensitivity Tests; Mutation; Phosphatidylserines; Rhodamines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1999 |
Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins.
Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Chloromethyl Ketones; Animals; bcl-2-Associated X Protein; Calcium; Caspases; Cell Death; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Cytosol; Dactinomycin; Dopamine; Dopamine Agents; Emetine; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Mesencephalon; Mice; Microscopy, Electron; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine | 1999 |
Degradation of human thyroperoxidase in the endoplasmic reticulum involves two different pathways depending on the folding state of the protein.
Topics: Acetylcysteine; Ammonium Chloride; Animals; Antibodies, Monoclonal; Chloroquine; CHO Cells; Cricetinae; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Emetine; Endoplasmic Reticulum; Humans; Multienzyme Complexes; Peroxidase; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Folding; Thyroid Gland | 2000 |
Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: evidence for cytotoxic mechanisms different from inhibition of protein synthesis.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Death; Cell Survival; Cycloheximide; Cytochrome c Group; Egg Proteins; Emetine; HeLa Cells; Humans; Leucine; Mitochondria; Protein Biosynthesis; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Ribonucleases; RNA, Messenger; RNA, Transfer; Substrate Specificity | 2000 |
Phrenic long-term facilitation requires spinal serotonin receptor activation and protein synthesis.
Topics: Animals; Cycloheximide; Emetine; Hypoglossal Nerve; Injections, Spinal; Long-Term Potentiation; Male; Methysergide; Motor Neurons; Neck; Neuronal Plasticity; Phrenic Nerve; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Respiration; Serotonin Antagonists; Spinal Cord; Vagotomy | 2002 |
Cycloheximide increases glucocorticoid-stimulated alpha -ENaC mRNA in collecting duct cells by p38 MAPK-dependent pathway.
Topics: Aldosterone; Animals; Cell Line; Cycloheximide; Dexamethasone; Dogs; Emetine; Enzyme Activators; Enzyme Inhibitors; Epithelial Sodium Channels; Gene Expression; Glucocorticoids; Hypotonic Solutions; Kidney Tubules, Collecting; Mifepristone; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; RNA, Messenger; Signal Transduction; Sodium Channels | 2003 |
Inhibition of puromycin-induced apoptosis in breast cancer cells by IGF-I occurs simultaneously with increased protein synthesis.
Topics: Apoptosis; Cell Line, Tumor; Cycloheximide; Dose-Response Relationship, Drug; Emetine; Female; Humans; Insulin-Like Growth Factor I; Protein Biosynthesis; Protein Synthesis Inhibitors; Puromycin; Receptor, IGF Type 1; RNA, Messenger | 2004 |
GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos.
Topics: Activins; Animals; Cycloheximide; DNA-Binding Proteins; Embryo, Nonmammalian; Emetine; Endoderm; GATA4 Transcription Factor; GATA5 Transcription Factor; GATA6 Transcription Factor; Gene Expression Regulation, Developmental; High Mobility Group Proteins; Liver; Protein Biosynthesis; Protein Synthesis Inhibitors; Signal Transduction; SOXF Transcription Factors; Transcription Factors; Transforming Growth Factor beta; Xenopus; Xenopus Proteins | 2005 |
Emetine regulates the alternative splicing of Bcl-x through a protein phosphatase 1-dependent mechanism.
Topics: Alternative Splicing; bcl-X Protein; Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Down-Regulation; Emetine; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Marine Toxins; Okadaic Acid; Oxazoles; Prostatic Neoplasms; Protein Phosphatase 1; Protein Phosphatase 2; Up-Regulation; Uterine Cervical Neoplasms | 2007 |
Infusion of protein synthesis inhibitors in the entorhinal cortex blocks consolidation but not reconsolidation of object recognition memory.
Topics: Animals; Anisomycin; Cycloheximide; Emetine; Entorhinal Cortex; Male; Memory, Short-Term; Pattern Recognition, Physiological; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Recognition, Psychology | 2009 |
Limited uptake of the cyanobacterial toxin cylindrospermopsin by Vero cells.
Topics: Alkaloids; Animals; Bacterial Toxins; Cell-Free System; Chlorocebus aethiops; Culture Media; Cyanobacteria; Cyanobacteria Toxins; Cycloheximide; Emetine; Flow Cytometry; Temperature; Uracil; Vero Cells | 2009 |
Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice.
Topics: Animals; Carrier Proteins; Cells, Cultured; Codon, Nonsense; Cycloheximide; Disease Models, Animal; Emetine; Exons; Gene Knock-In Techniques; Homozygote; Hypertrophy, Left Ventricular; Mice; Mice, Mutant Strains; Mice, Transgenic; Muscle Cells; Point Mutation; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; RNA Stability; Ubiquitin | 2009 |
Emetine treatment masks initial LTP without affecting long-term stability.
Topics: Action Potentials; Animals; Anisomycin; Cycloheximide; Dose-Response Relationship, Drug; Emetine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Presynaptic Terminals; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Time Factors | 2011 |
Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by calcium-activated protease calpain.
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Calcium; Calcium Ionophores; Calpain; Cycloheximide; Cysteine Proteinase Inhibitors; Dipeptides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Emetine; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Ionomycin; K Cl- Cotransporters; Leupeptins; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Pyramidal Cells; Rats; Rats, Wistar; Statistics, Nonparametric; Symporters; Valine | 2012 |
Anti-protozoal and anti-bacterial antibiotics that inhibit protein synthesis kill cancer subtypes enriched for stem cell-like properties.
Topics: Acriflavine; Anti-Bacterial Agents; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Dactinomycin; Drug Repositioning; Emetine; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; High-Throughput Screening Assays; Humans; Mammary Glands, Human; Microarray Analysis; Neoplastic Stem Cells; Phenotype; Protein Biosynthesis; Protein Synthesis Inhibitors; Puromycin; Ribosomes | 2015 |
Novel Synergistic Anti-Enteroviral Drug Combinations.
Topics: Anisomycin; Antiviral Agents; Cycloheximide; Drug Combinations; Emetine; Enterovirus Infections; Humans; Picornaviridae; Vemurafenib | 2022 |