Page last updated: 2024-08-21

emetine and cephaelin

emetine has been researched along with cephaelin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199015 (55.56)18.7374
1990's1 (3.70)18.2507
2000's6 (22.22)29.6817
2010's3 (11.11)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Bedir, E; Dunbar, DC; Ferreira, D; Khan, SI; Muhammad, I; Takamatsu, S; Tekwani, BL; Walker, LA1
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Gupta, RS; Siminovitch, L1
Aoyama, T; Higuchi, S; Noda, K; Otsubo, K; Saita, M; Shimozono, Y; Suzuki, A; Teshima, D1
Elvidge, DA; Harrison, JR; Johnson, GW1
Lachman, MF; McComb, RB; Romeo, R1
Jha, S; Mahato, SB; Sahu, NP1
Romig, RA1
Hutzler, JM; Rosencrance, JG; Scharman, EJ; Tracy, TS1
Asano, T; Ishihara, K; Kamei, H; Kimura, M; Kushida, H; Sadakane, C; Wakui, Y; Yanagisawa, T; Yoshida, T1
Asano, T; Ishihara, K; Kamei, H; Kimura, M; Sadakane, C; Yanagisawa, T1
Endo, T; Fugii, Y; Hamaue, N; Hasegawa, M; Hirafuji, M; Minami, M; Nemoto, M; Ogawa, T; Takeda, Y; Tamakai, H1
Fujii, Y; Hasegawa, M; Kimura, M; Sadakane, K; Sasaki, T; Tabuchi, M; Takeda, Y1
GRY, O1
JINDRA, A; JUNGR, V; ZYKA, J1
COCCONCELLI, C1
MORCH, J1
BENEDETTI-VALENTINI, S; LUMINARI, M1
NARAIN, N1
PIETURA, A; WISNIEWSKI, W1
BOYD, EM; KNIGHT, LM1
SCHAAFSMA, J1
Kutchan, TM; Nomura, T1
ALLEGRE, CF1
Batista, FR; de Oliveira, LO; Martins, ER; Rossi, AA; Silva, RS1
Borgato, GB; Castilho, RM; de Castro JĂșnior, G; Kowalski, LP; Lopes, MA; Martins, MD; Nor, JE; Rocha, GZ; Santos-Silva, AR; Silva, LC; Squarize, CH; Vargas, PA; Wagner, VP1

Trials

1 trial(s) available for emetine and cephaelin

ArticleYear
Single dose pharmacokinetics of syrup of ipecac.
    Therapeutic drug monitoring, 2000, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Area Under Curve; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Monitoring; Emetics; Emetine; Female; Humans; Ipecac; Male; Middle Aged

2000

Other Studies

26 other study(ies) available for emetine and cephaelin

ArticleYear
Antiparasitic alkaloids from Psychotria klugii.
    Journal of natural products, 2003, Volume: 66, Issue:7

    Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leishmania donovani; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peru; Plants, Medicinal; Plasmodium falciparum; Psychotria; Quinazolines; Tumor Cells, Cultured

2003
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
    Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061

    Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites

2011
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Mutants of CHO cells resistant to the protein synthesis inhibitors, cryptopleurine and tylocrebrine: genetic and biochemical evidence for common site of action of emetine, cryptopleurine, tylocrebine, and tubulosine.
    Biochemistry, 1977, Jul-12, Volume: 16, Issue:14

    Topics: Alkaloids; Animals; Anisomycin; Cells, Cultured; Cricetinae; Cross Reactions; Cycloheximide; Drug Resistance; Emetine; Female; Hybrid Cells; Indoles; Isoquinolines; Mutation; Ovary; Pactamycin; Phenanthrenes; Protein Biosynthesis; Quinolizines; Sparsomycin; Structure-Activity Relationship; Trichodermin

1977
Efficacy of emetic and United State pharmacopoeia ipecac syrup in prevention of drug absorption.
    Chemical & pharmaceutical bulletin, 1990, Volume: 38, Issue:8

    Topics: Absorption; Animals; Dogs; Emetics; Emetine; Ipecac; Male; Pharmaceutical Preparations; Poisoning; Random Allocation

1990
Selective, stability-indicating assay of the major ipecacuanha alkaloids, emetine and cephaeline, in pharmaceutical preparations by high-performance liquid chromatography using spectrofluorimetric detection.
    Journal of chromatography, 1989, Jan-20, Volume: 463, Issue:1

    Topics: Chromatography, High Pressure Liquid; Emetine; Pharmaceutical Preparations; Spectrometry, Fluorescence

1989
Emetine identified in urine by HPLC, with fluorescence and ultraviolet/diode array detection, in a patient with cardiomyopathy.
    Clinical chemistry, 1989, Volume: 35, Issue:3

    Topics: Adolescent; Cardiomyopathy, Dilated; Chromatography, High Pressure Liquid; Emetine; Feeding and Eating Disorders; Female; Humans

1989
Production of the alkaloids emetine and cephaeline in callus cultures of Cephaelis ipecacuanha.
    Planta medica, 1988, Volume: 54, Issue:6

    Topics: Cells, Cultured; Culture Media; Emetics; Emetine; Plants, Medicinal

1988
The potential toxicity of ipecac.
    The American journal of psychiatry, 1984, Volume: 141, Issue:12

    Topics: Anorexia Nervosa; Emetine; Female; Heart Diseases; Humans; Ipecac

1984
Metabolism of ipecac alkaloids cephaeline and emetine by human hepatic microsomal cytochrome P450s, and their inhibitory effects on P450 enzyme activities.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:6

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Emetics; Emetine; Humans; Methylation; Microsomes, Liver; Recombinant Proteins

2001
High-performance liquid chromatographic assay with fluorescence detection for the determination of cephaeline and emetine in human plasma and urine.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Jun-15, Volume: 757, Issue:2

    Topics: Chromatography, High Pressure Liquid; Emetics; Emetine; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence

2001
Pharmacological aspects of ipecac syrup (TJN-119)-induced emesis in ferrets.
    Research communications in molecular pathology and pharmacology, 2000, Volume: 108, Issue:3-4

    Topics: Afferent Pathways; Animals; Emetics; Emetine; Ferrets; Hydroxyindoleacetic Acid; Ileum; Ipecac; Medulla Oblongata; Models, Biological; Serotonin; Vagus Nerve; Vomiting

2000
Studies for the emetic mechanisms of ipecac syrup (TJN-119) and its active components in ferrets: involvement of 5-hydroxytryptamine receptors.
    Japanese journal of pharmacology, 2002, Volume: 89, Issue:2

    Topics: Animals; Cell Line; Cricetinae; Dopamine; Emetics; Emetine; Ferrets; Guinea Pigs; Humans; Ipecac; Male; Protein Binding; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sulpiride

2002
Polarographic determination of cephaeline.
    Acta pharmaceutica internationalia, 1953, Volume: 2, Issue:5

    Topics: Alkaloids; Emetine; Polarography

1953
The polarographic determination of cephaeline.
    Acta pharmaceutica internationalia, 1953, Volume: 2, Issue:5

    Topics: Alkaloids; Emetine; Polarography

1953
[Therapeutic effect of cephaline extracted from the brain of oxen].
    Il Policlinico. Sezione pratica, 1956, Sep-17, Volume: 63, Issue:38

    Topics: Brain; Cholesterol; Electroconvulsive Therapy; Emetine; Glycerophosphates; Humans; Mental Disorders; Psychosurgery; Thiamine

1956
[The purity test for cephaeline in emetine chloride, Ph. Dan. 1948].
    Dansk tidsskrift for farmaci, 1957, Volume: 31, Issue:4

    Topics: Cephaelis; Chlorides; Emetine; Humans; Ions; Ipecac

1957
[Remarks on various liver function tests (Takata-Ara, cephaline-cholesterol, thymol) in relation to surgical intervention].
    Minerva medica, 1957, Sep-19, Volume: 48, Issue:75

    Topics: Cholesterol; Emetine; Humans; Liver; Liver Function Tests; Surgical Procedures, Operative; Thymol

1957
Studies on two new cephaline gregarines from the intestine of Indian insects, Gryllodes sigillatus and Liogryllus bimaculatus.
    Parasitology, 1961, Volume: 51

    Topics: Animals; Apicomplexa; Emetine; Insecta; Intestines

1961
[Colorimetric method for the determination of emetine and cephaeline in Cephaelis roots and in galenicals obtained from them].
    Acta poloniae pharmaceutica, 1963, Volume: 20

    Topics: Cephaelis; Emetine; Ipecac; Plant Roots; Plants, Medicinal

1963
THE EXPECTORANT ACTION OF CEPHAELINE, EMETINE AND 2-DEHYDROEMETINE.
    The Journal of pharmacy and pharmacology, 1964, Volume: 16

    Topics: Alkaloids; Cats; Emetine; Expectorants; Pharmacology; Rabbits; Research; Toxicology

1964
[Determination of cephaeline in emetine hydrochloride].
    Pharmaceutisch weekblad, 1951, May-12, Volume: 86, Issue:19-20

    Topics: Emetine; Isoquinolines

1951
Three new O-methyltransferases are sufficient for all O-methylation reactions of ipecac alkaloid biosynthesis in root culture of Psychotria ipecacuanha.
    The Journal of biological chemistry, 2010, Mar-05, Volume: 285, Issue:10

    Topics: Cephaelis; Chromatography, Liquid; Emetics; Emetine; Isoenzymes; Methylation; Methyltransferases; Molecular Sequence Data; Molecular Structure; Phylogeny; Plant Roots; Recombinant Fusion Proteins; Tandem Mass Spectrometry

2010
A preliminary report on the life history of a cephaline gregarine from the alimentary tract of the grasshopper Melanoplus differentialis.
    The Anatomical record, 1946, Volume: 96, Issue:4

    Topics: Animals; Apicomplexa; Emetine; Gastrointestinal Tract; Grasshoppers; Life Cycle Stages; Parasites

1946
Molecular phylogeography of Carapichea ipecacuanha, an amphitropical shrub that occurs in the understory of both semideciduous and evergreen forests.
    Molecular ecology, 2010, Volume: 19, Issue:7

    Topics: Base Sequence; Brazil; DNA, Chloroplast; DNA, Plant; Ecosystem; Emetine; Genetic Variation; Genetics, Population; Geography; Molecular Sequence Data; Phylogeny; Plant Roots; Rubiaceae; Sequence Alignment; Sequence Analysis, DNA; Trees

2010
Cephaeline is an inductor of histone H3 acetylation and inhibitor of mucoepidermoid carcinoma cancer stem cells.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2022, Volume: 51, Issue:6

    Topics: Acetylation; Carcinoma, Mucoepidermoid; Cell Line, Tumor; Emetine; Histones; Humans; Neoplastic Stem Cells

2022