Compounds > emd 53998
Page last updated: 2024-09-05

emd 53998 and 1-methyl-3-isobutylxanthine

emd 53998 has been researched along with 1-methyl-3-isobutylxanthine in 3 studies

Compound Research Comparison

Studies
(emd 53998)		Trials
(emd 53998)		Recent Studies (post-2010)
(emd 53998)		Studies
(1-methyl-3-isobutylxanthine)		Trials
(1-methyl-3-isobutylxanthine)		Recent Studies (post-2010) (1-methyl-3-isobutylxanthine)
112095,1485279

Protein Interaction Comparison

ProteinTaxonomyemd 53998 (IC50)1-methyl-3-isobutylxanthine (IC50)
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)8.1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)31
Chain A, Phosphodiesterase 9AHomo sapiens (human)500
Chain A, Class I phosphodiesterase PDEB1Leishmania major580
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)698
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)40
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Phosphodiesterase Bos taurus (cattle)9.9
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)4
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1667
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)9.9
Adenosine receptor A1Rattus norvegicus (Norway rat)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)9.9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.242
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)3.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)0.1
Phosphodiesterase Rattus norvegicus (Norway rat)0.1

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hongo, K; Konishi, M; Kurihara, S; Kusakari, Y; Mochizuki, S1
Hongo, K; Kawai, M; Konishi, M; Kurihara, S; Kusakari, Y; Mochizuki, S1
Hongo, K; Kawai, M; Konishi, M; Kurihara, S; Kusakari, Y1

Other Studies

3 other study(ies) available for emd 53998 and 1-methyl-3-isobutylxanthine

ArticleYear
Estimation of myofibrillar responsiveness to Ca2+ in isolated rat ventricular myocytes.
    Pflugers Archiv : European journal of physiology, 1998, Volume: 436, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Size; Cells, Cultured; Electric Stimulation; Fluorescence; Fura-2; Heart Ventricles; Male; Myocardial Contraction; Myocardium; Myofibrils; Quinolines; Rats; Rats, Wistar; Tetany; Thapsigargin; Thiadiazines; Ventricular Function

1998
Use of tetanus to investigate myofibrillar responsiveness to Ca(2+) in isolated mouse ventricular myocytes.
    The Japanese journal of physiology, 2002, Volume: 52, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium; Calcium-Transporting ATPases; Cardiotonic Agents; Cell Separation; Enzyme Inhibitors; Fluorescence; Isoproterenol; Mice; Muscle Contraction; Myocardium; Myofibrils; Phosphodiesterase Inhibitors; Quinolines; Thapsigargin; Thiadiazines; Ventricular Function

2002
Use of the Ca-shortening curve to estimate the myofilament responsiveness to Ca2+ in tetanized rat ventricular myocytes.
    The journal of physiological sciences : JPS, 2006, Volume: 56, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Actin Cytoskeleton; Animals; Calcium; Cardiotonic Agents; Cell Size; Cyclic AMP; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Phosphodiesterase Inhibitors; Quinolines; Rats; Rats, Wistar; Tetany; Thiadiazines

2006