Compounds > em 523

Page last updated: 2024-09-05

em 523 and motilin

em 523 has been researched along with motilin in 13 studies

Compound Research Comparison

Studies (em 523)	Trials (em 523)	Recent Studies (post-2010) (em 523)	Studies (motilin)	Trials (motilin)	Recent Studies (post-2010) (motilin)
26	1	0	1,337	135	181

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (7.69)	18.7374
1990's	11 (84.62)	18.2507
2000's	1 (7.69)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ito, Z; Kondo, Y; Mizumoto, A; Omura, S; Otawa, M	1
Matthijs, G; Peeters, TL; Vantrappen, G	1
Inatomi, N; Itoh, Z; Marui, S; Omura, S; Satoh, H; Satoh, T	1
Hashimoto, N; Inatomi, N; Itoh, Z; Maki, Y; Omura, S; Satoh, H	1
Haga, N; Inatomi, N; Itoh, Z; Mizumoto, A; Shiba, Y; Yamamoto, O	1
Inatomi, N; Itoh, Z; Omura, S; Satoh, H; Satoh, T	1
Depoortere, I; Dharanipragada, R; Florance, JR; Galdes, A; Macielag, MJ; Marvin, MS; Peeters, TL	1
Hayashi, N; Itoh, Z; Mizumoto, A; Ohtawa, M; Omura, S; Yanagida, K	1
Itoh, Z; Kawamura, O; Omura, S; Sekiguchi, T	1
Inui, A; Itoh, Z; Mizumoto, A; Omura, S; Satoh, M; Shiba, Y	1
Aoyama, N; Baba, S; Inui, A; Kasuga, M; Miyamoto, M; Morimoto, S; Nakajima, Y; Ohmoto, A; Okano, H; Ueno, N	1
Kitazawa, T; Ohga, A; Taneike, T	1
Akima, M; Itoh, Z; Kamei, K; Koga, H; Omura, S; Onoma, M; Ozaki, K; Sudo, H; Takanashi, H; Yogo, K	1

Other Studies

13 other study(ies) available for em 523 and motilin

Article	Year
[Effect of motilin agonist, EM-523 on gastrointestinal motility]. Nihon Geka Gakkai zasshi, 1991, Volume: 92, Issue:9 Topics: Animals; Dogs; Erythromycin; Gastrointestinal Motility; Motilin	1991
Ca2+ dependence of motilide-induced contractions in rabbit duodenal muscle strips in vitro. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:2 Topics: Animals; Calcium; Duodenum; Erythromycin; In Vitro Techniques; Molecular Structure; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits	1991
EM-523, an erythromycin derivative, and motilin show similar contractile activity in isolated rabbit intestine. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:3 Topics: Acetylcholine; Animals; Atropine; Dinoprost; Drug Interactions; Erythromycin; Female; Guinea Pigs; Intestine, Small; Male; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Tetrodotoxin	1990
An erythromycin derivative, EM-523, induces motilin-like gastrointestinal motility in dogs. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2 Topics: Animals; Atropine; Dogs; Erythromycin; Fasting; Gastrointestinal Motility; Male; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Vomiting	1989
Stimulatory mechanism of EM523-induced contractions in postprandial stomach of conscious dogs. Gastroenterology, 1995, Volume: 109, Issue:5 Topics: Animals; Anti-Bacterial Agents; Atropine; Dipeptides; Dogs; Dopamine; Eating; Erythromycin; Hexamethonium; Indoles; Motilin; Muscle Contraction; Naloxone; Ondansetron; Serotonin Antagonists; Stomach; Substance P	1995
Comparison of the motor-stimulating action of EM523, an erythromycin derivative, and prostaglandin F2 alpha in conscious dogs. Japanese journal of pharmacology, 1993, Volume: 63, Issue:2 Topics: Animals; Atropine; Dinoprost; Dogs; Dopamine; Erythromycin; Fasting; Gastrointestinal Motility; Male; Motilin	1993
The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. Biochemical and biophysical research communications, 1994, Jan-28, Volume: 198, Issue:2 Topics: Animals; Binding, Competitive; Digestive System; Duodenum; Erythromycin; Motilin; Muscle Contraction; Muscle, Smooth; Pyloric Antrum; Rabbits	1994
Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs. Gastroenterology, 1993, Volume: 104, Issue:5 Topics: Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Motility; Immune Sera; Male; Motilin	1993
Effect of erythromycin derivative EM523L on human interdigestive gastrointestinal tract. Digestive diseases and sciences, 1993, Volume: 38, Issue:6 Topics: Adult; Digestion; Digestive System; Digestive System Physiological Phenomena; Dose-Response Relationship, Drug; Erythromycin; Gastrointestinal Motility; Humans; Male; Motilin; Reference Values; Time Factors	1993
Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs. Gastroenterology, 1996, Volume: 110, Issue:1 Topics: Animals; Atropine; Dogs; Erythromycin; Gastrointestinal Hormones; Motilin; Ondansetron; Pancreatic Hormones; Serotonin Antagonists; Vagotomy	1996
EM523L, a nonpeptide motilin agonist, stimulates gastric emptying and pancreatic polypeptide secretion. Peptides, 1996, Volume: 17, Issue:6 Topics: Adult; Aged; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Erythromycin; Evaluation Studies as Topic; Female; Gastric Emptying; Gastrointestinal Agents; Humans; Male; Middle Aged; Motilin; Pancreatic Polypeptide	1996
Functional characterization of neural and smooth muscle motilin receptors in the chicken proventriculus and ileum. Regulatory peptides, 1997, Aug-15, Volume: 71, Issue:2 Topics: Animals; Chickens; Dogs; Erythromycin; Gastrointestinal Agents; Hormones; Ileum; Motilin; Muscle Contraction; Muscle, Smooth; Proventriculus; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Swine	1997
Effects of mitemcinal (GM-611), an acid-resistant nonpeptide motilin receptor agonist, on the gastrointestinal contractile activity in conscious dogs. Pharmacology, 2007, Volume: 79, Issue:4 Topics: Administration, Oral; Animals; Digestion; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Tract; Injections, Intravenous; Male; Motilin; Muscle Contraction; Muscle, Smooth; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2007