em 16 has been researched along with thalidomide in 3 studies
*Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action. [MeSH]
*Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action. [MeSH]
| Studies (em 16) | Trials (em 16) | Recent Studies (post-2010) (em 16) | Studies (thalidomide) | Trials (thalidomide) | Recent Studies (post-2010) (thalidomide) |
|---|---|---|---|---|---|
| 5 | 0 | 3 | 9,789 | 1,385 | 4,342 |
| Protein | Taxonomy | em 16 (IC50) | thalidomide (IC50) |
|---|---|---|---|
| Cereblon isoform 4 | Magnetospirillum gryphiswaldense | 7.8 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.37 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 0.5 | |
| DNA damage-binding protein 1 | Homo sapiens (human) | 1.38 | |
| Protein cereblon | Homo sapiens (human) | 1.38 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klinkmüller, KD; Schmahl, HJ; Winckler, K | 1 |
| Felies, A; Frankus, E; Jacob-Müller, U; Neubert, D; Neubert, R; Nogueira, AC | 1 |
| Acién, FG; Fernández-Sevilla, JM; Gómez, C; Granados, MR; Molina Grima, E | 1 |
3 other study(ies) available for em 16 and thalidomide
| Article | Year |
|---|---|
Determination of the thalidomide analogues 2-(2,6-dioxopiperidine-3-yl)phthalimidine (EM 12), 2-(2,6-dioxopiperidine-4-yl)phthalimidine (EM 16) and their metabolites in biological samples.
Topics: Animals; Callitrichinae; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Thalidomide | 1989 |
Thalidomide derivatives and the immune system. 6. Effects of two derivatives with no obvious teratogenic potency on the pattern of integrins and other surface receptors on blood cells of marmosets.
Topics: Animals; Antigens, CD; Callithrix; Cell Adhesion Molecules; Flow Cytometry; Immune System; Integrins; Leukocytes, Mononuclear; Lymphocyte Subsets; Membrane Glycoproteins; Membrane Proteins; Platelet Glycoprotein GPIb-IX Complex; Receptors, Cell Surface; Teratogens; Thalidomide | 1996 |
Evaluation of flocculants for the recovery of freshwater microalgae.
Topics: Biomass; Electrolytes; Flocculation; Fresh Water; Microalgae; Thalidomide | 2012 |