em 139 has been researched along with hydroxyflutamide in 3 studies
| Studies (em 139) | Trials (em 139) | Recent Studies (post-2010) (em 139) | Studies (hydroxyflutamide) | Trials (hydroxyflutamide) | Recent Studies (post-2010) (hydroxyflutamide) |
|---|---|---|---|---|---|
| 12 | 0 | 0 | 288 | 5 | 55 |
| Protein | Taxonomy | em 139 (IC50) | hydroxyflutamide (IC50) |
|---|---|---|---|
| Progesterone receptor | Homo sapiens (human) | 2.013 | |
| Androgen receptor | Homo sapiens (human) | 0.9313 | |
| Androgen receptor | Mus musculus (house mouse) | 0.6073 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bydal, P; Labrie, F; Luu-The, V; Poirier, D | 1 |
| de Launoit, Y; Dufour, M; Labrie, F; Simard, J; Veilleux, R | 1 |
| Dauvois, S; Haagensen, DE; Labrie, F; Lévesque, C; Mérand, Y; Simard, J | 1 |
3 other study(ies) available for em 139 and hydroxyflutamide
| Article | Year |
|---|---|
Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities.
Topics: 17-Hydroxysteroid Dehydrogenases; Cell Line; Cell Proliferation; Enzyme Inhibitors; Humans; Lactones; Male; Prostatic Diseases; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Steroids; Structure-Activity Relationship | 2009 |
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; Estrone; Flow Cytometry; Flutamide; Humans; In Vitro Techniques; Male; Metribolone; Piperidines; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen; Testosterone; Time Factors; Tumor Cells, Cultured | 1991 |
Regulation of progesterone-binding breast cyst protein GCDFP-24 secretion by estrogens and androgens in human breast cancer cells: a new marker of steroid action in breast cancer.
Topics: Androgens; Apolipoproteins; Apolipoproteins D; Binding, Competitive; Biomarkers, Tumor; Breast Neoplasms; Carrier Proteins; Cell Division; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Estrogens; Female; Flutamide; Glycoproteins; Humans; Kinetics; Membrane Transport Proteins; Neoplasm Proteins; Progesterone; Tumor Cells, Cultured | 1990 |