em 139 has been researched along with dihydrotestosterone in 5 studies
| Studies (em 139) | Trials (em 139) | Recent Studies (post-2010) (em 139) | Studies (dihydrotestosterone) | Trials (dihydrotestosterone) | Recent Studies (post-2010) (dihydrotestosterone) |
|---|---|---|---|---|---|
| 12 | 0 | 0 | 9,325 | 307 | 1,517 |
| Protein | Taxonomy | em 139 (IC50) | dihydrotestosterone (IC50) |
|---|---|---|---|
| Plasma kallikrein | Homo sapiens (human) | 0.0031 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.54 | |
| Sex hormone-binding globulin | Homo sapiens (human) | 0.0038 | |
| Progesterone receptor | Oryctolagus cuniculus (rabbit) | 0.44 | |
| Progesterone receptor | Homo sapiens (human) | 7.3 | |
| Mineralocorticoid receptor | Homo sapiens (human) | 0.36 | |
| Sex hormone-binding globulin | Rattus norvegicus (Norway rat) | 0.023 | |
| Androgen receptor | Homo sapiens (human) | 0.0048 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.4041 | |
| Androgen receptor | Mus musculus (house mouse) | 0.001 | |
| Mineralocorticoid receptor | Rattus norvegicus (Norway rat) | 2.1 | |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | 0.0026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bydal, P; Labrie, F; Luu-The, V; Poirier, D | 1 |
| de Launoit, Y; Dufour, M; Labrie, F; Simard, J; Veilleux, R | 1 |
| Dauvois, S; de Launoit, Y; Dufour, M; Labrie, F; Simard, J | 1 |
| Dauvois, S; Geng, CS; Labrie, F; Lévesque, C; Mérand, Y | 1 |
| Dauvois, S; Haagensen, DE; Labrie, F; Lévesque, C; Mérand, Y; Simard, J | 1 |
5 other study(ies) available for em 139 and dihydrotestosterone
| Article | Year |
|---|---|
Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities.
Topics: 17-Hydroxysteroid Dehydrogenases; Cell Line; Cell Proliferation; Enzyme Inhibitors; Humans; Lactones; Male; Prostatic Diseases; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Steroids; Structure-Activity Relationship | 2009 |
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; Estrone; Flow Cytometry; Flutamide; Humans; In Vitro Techniques; Male; Metribolone; Piperidines; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen; Testosterone; Time Factors; Tumor Cells, Cultured | 1991 |
Inhibition of cell cycle kinetics and proliferation by the androgen 5 alpha-dihydrotestosterone and antiestrogen N,n-butyl-N-methyl-11-[16' alpha-chloro-3',17 beta-dihydroxy-estra-1',3',5'-(10')triene-7' alpha-yl] undecanamide in human breast cancer ZR-75
Topics: Breast Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Division; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Humans; Interphase; Tumor Cells, Cultured | 1991 |
Additive inhibitory effects of an androgen and the antiestrogen EM-170 on estradiol-stimulated growth of human ZR-75-1 breast tumors in athymic mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Dihydrotestosterone; Drug Implants; Estradiol; Estrogen Antagonists; Female; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Ovariectomy; Transplantation, Heterologous | 1991 |
Regulation of progesterone-binding breast cyst protein GCDFP-24 secretion by estrogens and androgens in human breast cancer cells: a new marker of steroid action in breast cancer.
Topics: Androgens; Apolipoproteins; Apolipoproteins D; Binding, Competitive; Biomarkers, Tumor; Breast Neoplasms; Carrier Proteins; Cell Division; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Estrogens; Female; Flutamide; Glycoproteins; Humans; Kinetics; Membrane Transport Proteins; Neoplasm Proteins; Progesterone; Tumor Cells, Cultured | 1990 |