ellipticine and mitoxantrone

ellipticine has been researched along with mitoxantrone in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's2 (20.00)18.2507
2000's5 (50.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Denny, WA; Feigon, J; Kearns, DR; Leupin, W1
Kostakis, IK; Léonce, S; Magiatis, P; Marakos, P; Pierré, A; Pouli, N; Pratsinis, H; Skaltsounis, AL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Sumner, AT1
Darzynkiewicz, Z; Kapuscinski, J; Traganos, F1
Kreuzer, KN; O'Reilly, EK1
Hait, WN; Nayak, MS; Yang, JM1
Dudgeon, DD; Giuliano, KA; Johnston, PA; Lazo, JS; Shinde, SN; Shun, TY; Strock, CJ; Taylor, DL1
Pham, XH; Tran, NQ; Tuteja, N; Tuteja, R1

Other Studies

10 other study(ies) available for ellipticine and mitoxantrone

ArticleYear
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship

1984
Design, synthesis, and antiproliferative activity of some new pyrazole-fused amino derivatives of the pyranoxanthenone, pyranothioxanthenone, and pyranoacridone ring systems: a new class of cytotoxic agents.
    Journal of medicinal chemistry, 2002, Jun-06, Volume: 45, Issue:12

    Topics: Acridines; Animals; Antineoplastic Agents; DNA; Drug Screening Assays, Antitumor; Fluorescence; Humans; Intercalating Agents; Mice; Structure-Activity Relationship; Tumor Cells, Cultured; Xanthenes

2002
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Inhibitors of topoisomerases do not block the passage of human lymphocyte chromosomes through mitosis.
    Journal of cell science, 1992, Volume: 103 ( Pt 1)

    Topics: Amsacrine; Camptothecin; Chromosome Aberrations; Chromosomes, Human; Daunorubicin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Ellipticines; Ethidium; Etoposide; Humans; In Vitro Techniques; Lymphocytes; Mitosis; Mitoxantrone; Nalidixic Acid; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1992
Caffeine modulates the effects of DNA-intercalating drugs in vitro: a flow cytometric and spectrophotometric analysis of caffeine interaction with novantrone, doxorubicin, ellipticine, and the doxorubicin analogue AD198.
    Cancer research, 1991, Jul-15, Volume: 51, Issue:14

    Topics: Acridine Orange; Animals; Caffeine; Cell Cycle; Cell Division; Doxorubicin; Drug Interactions; Ellipticines; Flow Cytometry; Mice; Mitoxantrone; Nucleic Acids; Spectrophotometry

1991
A unique type II topoisomerase mutant that is hypersensitive to a broad range of cleavage-inducing antitumor agents.
    Biochemistry, 2002, Jun-25, Volume: 41, Issue:25

    Topics: Amino Acid Sequence; Amino Acid Substitution; Amsacrine; Antineoplastic Agents; Bacteriophage T4; Binding Sites; DNA Damage; DNA Topoisomerases, Type II; DNA, Superhelical; Ellipticines; Enzyme Inhibitors; Filtration; Glycine; Mitoxantrone; Molecular Sequence Data; Oxolinic Acid; Podophyllotoxin; Point Mutation; Topoisomerase II Inhibitors; Valine

2002
Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs.
    Cancer research, 2007, Jun-15, Volume: 67, Issue:12

    Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Line, Tumor; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Ellipticines; Etoposide; Humans; Immunoblotting; Mice; Microscopy, Confocal; Mitoxantrone; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Reverse Transcriptase Polymerase Chain Reaction

2007
Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.
    Assay and drug development technologies, 2010, Volume: 8, Issue:4

    Topics: Antineoplastic Agents; Biosensing Techniques; Camptothecin; Cell Line, Tumor; Checkpoint Kinase 2; Ellipticines; Genes, p53; High-Throughput Screening Assays; Humans; Imidazoles; Mitoxantrone; Piperazines; Protein Binding; Protein Interaction Mapping; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-mdm2; Recombinant Fusion Proteins; Small Molecule Libraries; Spectrometry, Fluorescence; Topotecan; Tumor Suppressor Protein p53

2010
Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin.
    Plant signaling & behavior, 2011, Volume: 6, Issue:3

    Topics: Adenosine Triphosphatases; Camptothecin; Cisplatin; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Enzyme Inhibitors; Etoposide; Intercalating Agents; Mitoxantrone; Nogalamycin; Novobiocin; Pisum sativum; Plant Proteins

2011