ellipticine has been researched along with deoxyguanosine in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borek-Dohalská, L; Frei, E; Stiborová, M; Stiborová-Rupertová, M; Wiessler, M | 1 |
| Dracínský, M; Eckschlager, T; Frei, E; Poljaková, J; Ryslavá, H; Stiborová, M | 1 |
2 other study(ies) available for ellipticine and deoxyguanosine
| Article | Year |
|---|---|
Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans.
Topics: Animals; Antineoplastic Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deoxyguanosine; DNA; DNA Adducts; Ellipticines; Enzyme Inhibitors; Humans; Isoenzymes; Microsomes, Liver; Models, Animal; Phosphorus Radioisotopes; Rabbits; Rats; Species Specificity | 2003 |
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine.
Topics: Animals; Antineoplastic Agents; Cattle; Deoxyguanosine; DNA; DNA Adducts; Ellipticines; Humans; Kidney; Microsomes; Microsomes, Liver; Oxidation-Reduction; Peroxidases | 2007 |