ellipticine and camptothecin

ellipticine has been researched along with camptothecin in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (31.82)18.2507
2000's6 (27.27)29.6817
2010's9 (40.91)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hwang, HJ; Kim, JS; Kim, YS; Lee, EJ; Lee, SK; Park, HJ; Ryu, CK; Suh, ME; Yi, YJ1
Choo, HY; Kim, JS; Lee, HJ; Lee, IK; Lee, SK; Park, HJ; Rhee, HK; Ryu, CK; Suh, ME1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Cho, WJ; Kang, BY; Kwon, Y; Le, QM; Lee, ES; Lee, SK; My Van, HT; Youl Lee, K1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Cho, WJ; Khadka, DB1
Cho, SH; Cho, WJ; Khadka, DB; Kwon, Y; Le, QM; Le, TN; Lee, ES; Lee, KT; Van, HT; Yang, SH1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Cao, HT; Chau, MV; Cho, WJ; Jin, Y; Khadka, DB; Kwon, Y; Le, TN; Nguyen, HT; Shin, S; Tran, GH; Van, HT; Zhao, C1
Bist, G; Kadayat, TM; Kwon, Y; Lee, ES; Lee, HJ; Park, S; Shrestha, A; Thapa Magar, TB1
Barresi, E; Da Settimo, F; Dalla Via, L; García-Argáez, AN; Hyeraci, M; La Pietra, V; Marinelli, L; Marini, AM; Milite, C; Novellino, E; Robello, M; Salerno, S; Simorini, F; Taliani, S1
Liu, Y; Xu, Z; Zhao, SJ1
Sumner, AT1
Hsu, MT; Wong, ML1
Shin, CG; Snapka, RM1
Kawanishi, M1
Frei, H; Würgler, FE1
Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R1
Phan, TN; Tuteja, N1
Deslandes, E; Gauduchon, P; Godard, T; Poul, JM; Sichel, F1
Dudgeon, DD; Giuliano, KA; Johnston, PA; Lazo, JS; Shinde, SN; Shun, TY; Strock, CJ; Taylor, DL1
Pham, XH; Tran, NQ; Tuteja, N; Tuteja, R1

Reviews

2 review(s) available for ellipticine and camptothecin

ArticleYear
3-Arylisoquinolines as novel topoisomerase I inhibitors.
    Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2

    Topics: Antineoplastic Agents; DNA Topoisomerases, Type I; Isoquinolines; Topoisomerase I Inhibitors

2011
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles

2019

Other Studies

20 other study(ies) available for ellipticine and camptothecin

ArticleYear
6-Arylamino-7-chloro-quinazoline-5,8-diones as novel cytotoxic and DNA topoisomerase inhibitory agents.
    Bioorganic & medicinal chemistry letters, 2004, Jul-05, Volume: 14, Issue:13

    Topics: Antineoplastic Agents; Cell Line, Tumor; DNA Topoisomerases; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Quinazolines; Structure-Activity Relationship; Topoisomerase Inhibitors

2004
Synthesis of 6-chloroisoquinoline-5,8-diones and pyrido[3,4-b]phenazine-5,12-diones and evaluation of their cytotoxicity and DNA topoisomerase II inhibitory activity.
    Bioorganic & medicinal chemistry, 2007, Jan-01, Volume: 15, Issue:1

    Topics: Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; DNA; Drug Screening Assays, Antitumor; Drug Stability; Enzyme Inhibitors; Humans; Isoquinolines; Molecular Structure; Permeability; Phenazines; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors

2007
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Design, docking, and synthesis of novel indeno[1,2-c]isoquinolines for the development of antitumor agents as topoisomerase I inhibitors.
    Bioorganic & medicinal chemistry letters, 2007, Jul-01, Volume: 17, Issue:13

    Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; DNA; DNA Topoisomerases, Type I; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoquinolines; Models, Chemical; Models, Molecular; Topoisomerase Inhibitors; X-Rays

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Design, synthesis and docking study of 5-amino substituted indeno[1,2-c]isoquinolines as novel topoisomerase I inhibitors.
    Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

    Topics: Binding Sites; Cell Line, Tumor; Computer Simulation; DNA Topoisomerases, Type I; Drug Design; Humans; Isoquinolines; Piperazines; Quantitative Structure-Activity Relationship; Topoisomerase I Inhibitors

2011
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases.
    European journal of medicinal chemistry, 2015, Oct-20, Volume: 103

    Topics: Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Molecular Structure; Quinazolinones; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2015
Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Biocatalysis; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Design; Humans; Pyridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2017
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA; Humans; Indoles; Molecular Docking Simulation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2019
Inhibitors of topoisomerases do not block the passage of human lymphocyte chromosomes through mitosis.
    Journal of cell science, 1992, Volume: 103 ( Pt 1)

    Topics: Amsacrine; Camptothecin; Chromosome Aberrations; Chromosomes, Human; Daunorubicin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Ellipticines; Ethidium; Etoposide; Humans; In Vitro Techniques; Lymphocytes; Mitosis; Mitoxantrone; Nalidixic Acid; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1992
Involvement of topoisomerases in replication, transcription, and packaging of the linear adenovirus genome.
    Journal of virology, 1990, Volume: 64, Issue:2

    Topics: Adenoviruses, Human; Alkaloids; Blotting, Southern; Camptothecin; Cell Nucleus; Deoxyribonucleoproteins; DNA Replication; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Viral; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Ellipticines; Etoposide; HeLa Cells; Humans; Microscopy, Electron; Templates, Genetic; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transcription, Genetic

1990
Patterns of strongly protein-associated simian virus 40 DNA replication intermediates resulting from exposures to specific topoisomerase poisons.
    Biochemistry, 1990, Dec-11, Volume: 29, Issue:49

    Topics: Animals; Camptothecin; Chlorocebus aethiops; Deoxyribonucleoproteins; DNA Replication; DNA, Viral; Ellipticines; Etoposide; Proflavine; Simian virus 40; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1990
Topoisomerase I and II activities are required for Epstein-Barr virus replication.
    The Journal of general virology, 1993, Volume: 74 ( Pt 10)

    Topics: Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Viral; Ellipticines; Herpesvirus 4, Human; Virus Replication

1993
Induction of somatic mutation and recombination by four inhibitors of eukaryotic topoisomerases assayed in the wing spot test of Drosophila melanogaster.
    Mutagenesis, 1996, Volume: 11, Issue:4

    Topics: Animals; Camptothecin; Drosophila melanogaster; Ellipticines; Enzyme Inhibitors; Etoposide; Female; Male; Mutagenicity Tests; Mutation; Recombination, Genetic; Teniposide; Topoisomerase I Inhibitors

1996
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents.
    Biochemical and biophysical research communications, 1997, Jul-30, Volume: 236, Issue:3

    Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors

1997
Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands.
    Biochemical and biophysical research communications, 1998, Mar-27, Volume: 244, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amsacrine; Camptothecin; Chloroplasts; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Ethidium; Etoposide; Genistein; Hydrolysis; Intercalating Agents; Ligands; Nogalamycin; Novobiocin; Pisum sativum

1998
Detection of topoisomerase inhibitor-induced DNA strand breaks and apoptosis by the alkaline comet assay.
    Mutation research, 2002, Sep-26, Volume: 520, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Survival; CHO Cells; Comet Assay; Cricetinae; DNA Damage; DNA Fragmentation; Ellipticines; Enzyme Inhibitors; Etoposide; Formazans; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan

2002
Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.
    Assay and drug development technologies, 2010, Volume: 8, Issue:4

    Topics: Antineoplastic Agents; Biosensing Techniques; Camptothecin; Cell Line, Tumor; Checkpoint Kinase 2; Ellipticines; Genes, p53; High-Throughput Screening Assays; Humans; Imidazoles; Mitoxantrone; Piperazines; Protein Binding; Protein Interaction Mapping; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-mdm2; Recombinant Fusion Proteins; Small Molecule Libraries; Spectrometry, Fluorescence; Topotecan; Tumor Suppressor Protein p53

2010
Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin.
    Plant signaling & behavior, 2011, Volume: 6, Issue:3

    Topics: Adenosine Triphosphatases; Camptothecin; Cisplatin; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Enzyme Inhibitors; Etoposide; Intercalating Agents; Mitoxantrone; Nogalamycin; Novobiocin; Pisum sativum; Plant Proteins

2011