ellipticine and 9-hydroxyellipticine

ellipticine has been researched along with 9-hydroxyellipticine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19907 (50.00)18.7374
1990's3 (21.43)18.2507
2000's1 (7.14)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Archer, S; el-Hamouly, W; Modi, SP; Portuese, E; Ruckdeschel, JC1
Honda, T; Inoue, M; Kato, M; Nakanishi, T; Noguchi, T; Shima, K; Shimamoto, T; Yoshida, T1
Borgna, JL; Delbarre, A; Jacquemin-Sablon, A; Le Pecq, JB; Oberlin, R; Rochefort, H; Roques, BP1
Auclair, C; Hyland, K; Paoletti, C1
Denny, WA; Feigon, J; Kearns, DR; Leupin, W1
Auclair, C; Paoletti, C1
Acton, EM; Boyd, MR; Narayanan, VL; Risbood, PA; Shoemaker, RH; Vistica, DT1
Auclair, C; Dubreuil, P; Le Bret, M; Letard, S; Martin, F; Svinarchuk, F; Vendôme, J1
Amorim, RC; Costa, DS; Costa, MR; Eberlin, MN; Grafov, A; Grafova, I; Henrique, MC; Lima, ES; Montoia, A; Pohlit, AM; Rocha E Silva, LF; Souza, RC; Tadei, WP; Torres, ZE; Vasconcellos, MC1
Kato, A; Kawagoshi, M; Konakahara, T; Kurasaki, H; Morii, N; Sakai, N; Shimazu, A; Takeda, S1
Charcosset, JY; Garbay-Jaureguiberry, C; Jacquemin-Sablon, A; Rigaudy, P; Roques, BP1
Auclair, C; Lesca, P; Malvy, C; Paoletti, C; Pinto, M; Tocanne, JF1
Nakanishi, N; Ohashi, M; Sugikawa, E1
Omar, SI; Tuszynski, J1

Reviews

1 review(s) available for ellipticine and 9-hydroxyellipticine

ArticleYear
Ellipticine, 9-hydroxyellipticine, and 9-hydroxyellipiticinum: some biochemical properties of possible pharmacologic significance.
    Cancer treatment reports, 1981, Volume: 65 Suppl 3

    Topics: Alkaloids; Animals; Cytochrome P-450 Enzyme System; DNA; Ellipticines; Leukemia L1210; Membrane Lipids; Membranes, Artificial; Mixed Function Oxygenases; Oxidation-Reduction; Phospholipids

1981

Other Studies

13 other study(ies) available for ellipticine and 9-hydroxyellipticine

ArticleYear
N-methylcarbamate derivatives of ellipticine and olivacine with cytotoxic activity against four human lung cancer cell lines.
    Journal of medicinal chemistry, 1992, Dec-25, Volume: 35, Issue:26

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carbamates; Ellipticines; Humans; Leukemia L1210; Lung Neoplasms; Mice; Structure-Activity Relationship; Tumor Cells, Cultured

1992
Synthesis and antitumor activity of quaternary ellipticine glycosides, a series of novel and highly active antitumor agents.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:7

    Topics: Alkaloids; Animals; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Ellipticines; Glycosides; Leukemia L1210; Leukemia P388; Melanoma; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Neoplasms, Experimental; Sarcoma 180; Structure-Activity Relationship

1988
Ellipticine derivatives with an affinity to the estrogen receptor, an approach to develop intercalating drugs with a specific effect on the hormone-dependent breast cancer.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:6

    Topics: Alkaloids; Animals; Breast Neoplasms; Cattle; Cell Line; DNA; Ellipticines; Female; Humans; In Vitro Techniques; Intercalating Agents; Leukemia L1210; Neoplasms, Hormone-Dependent; Receptors, Estrogen

1985
Autoxidation of the antitumor drug 9-hydroxyellipticine and its derivatives.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:10

    Topics: Alkaloids; Chemical Phenomena; Chemistry; Edetic Acid; Ellipticines; Kinetics; Manganese; Oxidation-Reduction; Oxygen Consumption; Spectrophotometry; Structure-Activity Relationship; Superoxide Dismutase

1983
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship

1984
Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Alkaloids; Animals; Antineoplastic Agents; Biotransformation; Ellipticines; Hydrogen Peroxide; Mice; Oxidation-Reduction; Peroxidases; Structure-Activity Relationship

1981
Anticancer specificity of some ellipticinium salts against human brain tumors in vitro.
    Journal of medicinal chemistry, 1994, Jul-08, Volume: 37, Issue:14

    Topics: Brain Neoplasms; Drug Evaluation, Preclinical; Ellipticines; Humans; Structure-Activity Relationship; Tumor Cells, Cultured

1994
Molecular modeling of wild-type and D816V c-Kit inhibition based on ATP-competitive binding of ellipticine derivatives to tyrosine kinases.
    Journal of medicinal chemistry, 2005, Oct-06, Volume: 48, Issue:20

    Topics: Adenosine Triphosphate; Binding, Competitive; Ellipticines; Mutation; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit

2005
Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog.
    Bioorganic & medicinal chemistry letters, 2014, Jun-15, Volume: 24, Issue:12

    Topics: Animals; Antimalarials; Aspidosperma; Chloroquine; Disease Models, Animal; Ellipticines; Fibroblasts; Humans; Mice; Molecular Structure; Plant Bark; Plasmodium falciparum

2014
Determination of binding modes and binding constants for the complexes of 6H-pyrido[4,3-b]carbazole derivatives with DNA.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Animals; Binding Sites; Carbazoles; Cell Survival; DNA; Dose-Response Relationship, Drug; HeLa Cells; Humans; Mice; Models, Molecular; Molecular Structure; NIH 3T3 Cells; Quartz Crystal Microbalance Techniques; Structure-Activity Relationship; Tumor Cells, Cultured

2017
Attempts to target antitumor drugs toward opioid receptor-rich mouse tumor cells with enkephalin-ellipticinium conjugates.
    Cancer research, 1989, Apr-01, Volume: 49, Issue:7

    Topics: Alkaloids; Animals; DNA; DNA Topoisomerases, Type II; Drug Carriers; Ellipticines; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etoposide; Fluorescence; Mice; Rats; Receptors, Opioid

1989
Inhibition of p53 protein phosphorylation by 9-hydroxyellipticine: a possible anticancer mechanism.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Lewis Lung; CDC2-CDC28 Kinases; Cell Death; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Ellipticines; Enzyme Inhibitors; Histones; Humans; Mice; Mice, Inbred Strains; Microsomes; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1995
Ranking the Binding Energies of p53 Mutant Activators and Their ADMET Properties.
    Chemical biology & drug design, 2015, Volume: 86, Issue:2

    Topics: Alkylation; Amifostine; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Drug Evaluation, Preclinical; Ellipticines; Heterocyclic Compounds, 4 or More Rings; Humans; Kinetics; Ligands; Mercaptoethylamines; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; Oxepins; Protein Binding; Pyrimidines; Quinuclidines; Tumor Suppressor Protein p53

2015