egtazic acid has been researched along with inositol 1,4,5-trisphosphate in 267 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (12.36) | 18.7374 |
| 1990's | 173 (64.79) | 18.2507 |
| 2000's | 51 (19.10) | 29.6817 |
| 2010's | 10 (3.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Plant, S; Yoshida, S | 1 |
| Fukami, K; Han, JK; Nuccitelli, R | 1 |
| Hoth, M; Penner, R | 1 |
| Fredholm, BB; Gerwins, P | 1 |
| Cerpovicz, PF; Ochs, RS | 1 |
| Casteels, R; De Smedt, H; Droogmans, G; Missiaen, L | 1 |
| Muallem, S; Zhang, BX | 1 |
| Carter, TD; Ogden, D | 1 |
| Neher, E | 2 |
| Kawai, N; Kirino, T; Masuzawa, T; Oguro, K; Robinson, HP; Tsubokawa, H | 1 |
| Bird, GS; Glennon, MC; Leslie, BA; Putney, JW; Takemura, H; Thastrup, O | 1 |
| Amakawa, T; Ozaki, M | 1 |
| Brown, EJ; Rosales, C | 1 |
| Bobik, A; Little, PJ; Neylon, CB; Nickashin, A; Tkachuk, VA | 1 |
| Kawai, N; Kirino, T; Miwa, A; Robinson, HP; Tamura, A | 1 |
| Carroll, J; Swann, K | 1 |
| Rehn, M; Tayag, A; Tio, D; Warburton, D | 1 |
| Chandrasekar, B; Korc, M; Siwik, SA | 1 |
| Bougeret, C; Durand, H; Liepkalns, V | 1 |
| Iino, M | 1 |
| Dyer, D; Matute, C; Miledi, R; Tigyi, G | 1 |
| Di Virgilio, F; Lew, DP; Monod, A; Pittet, D; Pozzan, T | 1 |
| Gat-Yablonski, G; Sagi-Eisenberg, R | 1 |
| Akcicek, F; Ganz, MB; Goldenring, J; Hayslett, JP; Lewis, JJ; Nestler, EJ; Petzel, D | 1 |
| Tang, W; Ziboh, VA | 1 |
| Hosoi, K; Kodama, A; Shioda, Y; Sugita, K; Ueha, T | 1 |
| Somogyi, R; Stucki, JW | 1 |
| Enslen, H; Magun, BE; Muldoon, LL; Rodland, KD | 1 |
| Bird, GS; Menniti, FS; Potter, BV; Putney, JW; Takemura, H; Thastrup, O | 1 |
| Hamaguchi, Y; Mohri, T | 1 |
| Payne, R; Potter, BV | 1 |
| Cerletti, C; Molino, M; Romano, M | 1 |
| Eguchi, S; Emori, T; Hirata, Y; Imai, T; Kanno, K; Marumo, F; Ohta, K; Shichiri, M | 1 |
| Fesce, R; Malgaroli, A; Meldolesi, J | 1 |
| Hanke, DE; MacRobbie, EA; Thiel, G | 1 |
| Cocco, L; Gilmour, RS; Manzoli, FA; Martelli, AM | 1 |
| Fu, T; Mitsui, Y; Nozawa, Y; Okano, Y; Ozeki, T; Zhang, W | 1 |
| Andersson, T; Gustavsson, J; Jondal, M; Ng, J | 1 |
| Brock, TA; Danthuluri, NR | 1 |
| De Jonge, HR; Ploemacher, MC; Vaandrager, AB | 1 |
| Andersson, T; Bergstrand, H; Fällman, M | 1 |
| Ichida, T; Takuma, T | 1 |
| Ichinose, M; Maeno, T; Sawada, M | 1 |
| Hirono, C; Ito, I; Sugiyama, H | 1 |
| Matthews, G; Neher, E; Penner, R | 1 |
| Balsan, S; Edelman, A; Fritsch, J | 1 |
| Harootunian, AT; Kao, JP; Tsien, RY | 1 |
| Petersen, OH; Potter, BV; Wakui, M | 1 |
| Kitazawa, T; Kobayashi, S; Somlyo, AP; Somlyo, AV | 1 |
| Pruss, RM; Stauderman, KA | 1 |
| McCarren, M; Miller, RJ; Potter, BV | 1 |
| Meldolesi, J; Pandiella, A | 1 |
| Nånberg, E; Nedergaard, J | 1 |
| Gilligan, A; Glennon, C; Knowles, BB; Prentki, M | 1 |
| Banfić, H; Kukolja, S | 1 |
| Bull, R; Hidalgo, C; Irribarra, V; Jaimovich, E; Larralde, L; Oberhauser, A; Suárez-Isla, BA | 1 |
| Schumaker, KS; Sze, H | 1 |
| Kao, LS | 1 |
| Ambudkar, IS; Baum, BJ; Horn, VJ | 1 |
| Bonis, D; Giraud, F; Rossignol, B | 1 |
| Krause, KH; Snyder, PM; Welsh, MJ | 1 |
| Gershengorn, MC | 1 |
| Godt, RE; Nosek, TM; Williams, MF; Zeigler, ST | 1 |
| DiGuiseppi, J; Earp, HS; Harden, TK; Hepler, JR; Herman, B; Lovenberg, TW; Nakahata, N | 1 |
| Patel, R; Twigg, J; Whitaker, M | 1 |
| Asaka, M; Nakagaki, I; Sasaki, S; Takeda, H; Tsunoda, Y | 1 |
| Byrne, JH; Cleary, LJ; Scholz, KP | 1 |
| Fasolato, C; Meldolesi, J; Pandiella, A; Pozzan, T | 1 |
| Foster, RH | 1 |
| Dorée, M; Giraud, F; Le Bouffant, F; Le Peuch, C; Picard, A; Sladeczek, F | 1 |
| Brass, LF; Joseph, SK | 1 |
| Koepfer-Hobelsberger, B; Wieland, OH | 1 |
| Cuatrecasas, P; Lapetina, EG; Watson, SP | 1 |
| Fujisawa, Y; Fujita, N; Hayashi, H; Okamoto, M; Shibanaka, Y; Takai, M; Umemura, I | 1 |
| Gray, PT; Hassoni, AA | 2 |
| Wang, HL; Wu, T | 1 |
| Daniel, EE; Inazu, M; Pasyk, E | 1 |
| Horne, JH; Meyer, T | 2 |
| Furuyama, S; Negishi, T; Niisato, N; Ogata, Y; Sakurai, T; Sugiya, H | 1 |
| Artemenko, IP; Hokin, LE; Los, GV | 2 |
| Dissing, S; Gromada, J; Jørgensen, TD | 1 |
| Chaudhuri, AG; Ganguly, U | 1 |
| Karin, NJ; Meszaros, JG | 1 |
| Parekh, AB; Penner, R | 1 |
| Boyce, SY; Henry, RA; Kurz, T; Wolf, RA | 1 |
| Akaike, N; Uneyama, C; Uneyama, H | 1 |
| Nuccitelli, R; Smart, T; Yim, DL | 1 |
| Altiok, N; Fredholm, BB | 1 |
| Ito, S; Mochizuki-Oda, N; Nakajima, Y; Nakanishi, S | 1 |
| Boev, KK; Duridanova, DB; Gagov, HS | 1 |
| Calvert, CM; Sanders, D | 1 |
| Hicks, JL; Salter, MW | 1 |
| Alousi, AA; Thompson, SH; Wang, SS | 1 |
| Brown, DA; Fukuda, K; Hashii, M; Higashida, H; Ishizaka, N; Katayama, M; Kimura, Y; Noda, M | 1 |
| Désilets, M; Soboloff, J; Tsang, BK; Wade, MG; Wells, G | 1 |
| Droogmans, G; Gericke, M; Nilius, B; Oike, M | 1 |
| Bootman, MD; Casteels, R; De Smedt, H; Missiaen, L; Parys, JB | 1 |
| Grégoire, G; Loirand, G; Pacaud, P | 1 |
| Kawai, N; Masuzawa, T; Oguro, K; Rhee, TS; Robinson, HP; Takenawa, T; Tsubokawa, H | 1 |
| Kozawa, O; Oiso, Y; Saito, H; Suzuki, A | 1 |
| Ohmori, H; Shigemoto, T; Sugai, T; Yoshida, N | 1 |
| Graier, WF; Krejs, GJ; Kukovetz, WR; Simecek, S; Toplak, H; Wascher, TC | 1 |
| Champeil, P; Combettes, L | 1 |
| Galione, A; Varney, MA; Watson, SP | 1 |
| Colonna, R; Tatone, C | 1 |
| Espinoza, R; Roberts, D; Smart, T; Stith, BJ | 1 |
| Brooker, G; Mattie, M; Spiegel, S | 1 |
| Furuichi, T; Mikoshiba, K; Nahorski, SR; Nakade, S; Wojcikiewicz, RJ | 1 |
| Asmis, R; Dennis, EA; Randriamampita, C; Tsien, RY | 1 |
| Dytoc, M; Fedorko, L; Sherman, PM | 1 |
| Chueh, SH; Kao, LS | 1 |
| Nahorski, SR; Tobin, AB; Wojcikiewicz, RJ | 1 |
| Casteels, R; De Smedt, H; Missiaen, L; Parys, JB | 1 |
| Cabello, OA; Schilling, WP | 1 |
| Bominaar, AA; Kesbeke, F; Van Haastert, PJ | 1 |
| Fasolato, C; Hoth, M; Penner, R | 2 |
| Katada, T; Toratani, S; Yokosawa, H | 1 |
| Brown, JE; Faddis, MN | 1 |
| Dawra, RK; Rünzi, M; Saluja, AK; Steer, ML | 1 |
| Chang, WT; Chau, LY; Chen, CH; Hsu, YS; Hu, CY; Lin, TA; Shue, MJ; Sun, GY; Tsai, WH | 1 |
| Birnbaumer, L; Blitzer, RD; Caron, MG; Carty, DJ; Codina, J; Cotecchia, S; De Vivo, M; Lefkowitz, RJ; Omri, G; Premont, RT | 1 |
| Boekhoff, I; Breer, H; Hofmann, F; Korth, M; May, B; Penner, R; Pfeifer, A; Ruth, P; Wang, GX | 1 |
| Hara, N; Ichinose, M; Maeno, T; Sawada, M | 1 |
| Muallem, S; Zhang, BX; Zhao, H | 1 |
| Richardson, A; Taylor, CW | 1 |
| Busa, WB; Sullivan, KM; Wilson, KL | 1 |
| Lewis, RS; Zweifach, A | 1 |
| Parekh, AB; Stühmer, W; Terlau, H | 1 |
| Levy, S; Payne, R | 1 |
| Hofer, AM; Machen, TE | 1 |
| Casabiell, X; Casanueva, FF; Pandiella, A; Pombo, CM; Zugaza, JL | 1 |
| Emmrich, F; Guse, AH; Roth, E | 1 |
| Patel, S; Taylor, CW | 1 |
| Thompson, SH; Wang, SS | 1 |
| Hanley, MR; Kim, HY; Thomas, D | 1 |
| Mathes, C; Thompson, SH | 1 |
| Cardone, MH; Mennitt, PA; Mochly-Rosen, D; Mostov, KE; Silver, RB; Smith, BL | 1 |
| Strauss, O; Wiederholt, M; Wienrich, M | 1 |
| Alessandro, R; Brilley, E; Felder, CC; Jacobs, W; Kohn, EC; Probst, J | 1 |
| Meyer, T; Oancea, E | 1 |
| Shuttleworth, TJ | 1 |
| Armant, DR; Stachecki, JJ | 1 |
| Espinoza, R; Goalstone, ML; Mossel, C; Roberts, D; Stith, BJ; Wiernsperger, N | 1 |
| Reber, BF; Schindelholz, B | 1 |
| Akamatsu, N; Higaki, T; Imamura, H; Kato, K; Kobayashi, K; Komatsu, S; Nakagawa, K; Nakagawa, M; Sato, T; Sawada, S; Shirai, K; Tada, Y; Tamagaki, T; Toratani, A; Tsuji, H; Yamada, K; Yamagami, M; Yamamoto, K; Yamasaki, S | 1 |
| Clapham, DE; Jaconi, M; Perez-Terzic, C; Pyle, J; Stehno-Bittel, L | 1 |
| Grosse, B; Lieberherr, M; Machelon, V; Nomé, F | 1 |
| Elmoselhi, AB; Grover, AK; Samson, SE | 1 |
| Helmke, R; Martinez, JR; Puente, S; Wells, J; Willis, S; Zhang, GH | 1 |
| Almers, W; Hille, B; Horstmann, H; Tse, A; Tse, FW | 1 |
| Payne, R; Ukhanov, K | 1 |
| Furuichi, T; Michikawa, T; Mikoshiba, K; Miyawaki, A; Yoneshima, H | 1 |
| Fuentes, E; McNaughton, PA; Nadal, A; Pastor, J | 1 |
| Borowitz, JL; Gunasekar, PG; Isom, GE; Yang, CW | 1 |
| Bernstein, KE; Harp, JB; Marrero, MB; Sayeski, PP; Scanlon, M | 1 |
| Marsault, R; Murgia, M; Pozzan, T; Rizzuto, R | 1 |
| Gant, TM; Marshall, IC; Wilson, KL | 1 |
| Babich, M; Foti, LR; Mathias, KL | 1 |
| Jayaraman, T; Marks, AR | 1 |
| Homburg, CH; Ibarrola, I; Kessler, J; Koenderman, L; Roos, D; Schweizer, RC; Verhoeven, AJ; Vossebeld, PJ | 1 |
| Becker, PL; Guo, X | 1 |
| Edwards, SW; Gasmi, L; Watson, F | 1 |
| Dissing, S; Gromada, J | 1 |
| Jena, M; Minore, JF; O'Neill, WC | 1 |
| Hosomi, H; Kawahara, K; Mori, M; Nishizaki, T; Okada, Y | 1 |
| Hinkle, PM; Yu, R | 1 |
| Kang, HY; Kang, WH; Lee, C | 1 |
| Kim, CJ; Macdonald, RL; Weir, BK; Zhang, H | 1 |
| Ito, S; Nakazato, Y; Ohta, T | 1 |
| Hirose, K; Iino, M; Kadowaki, S | 1 |
| Mikoshiba, K; Muto, A | 1 |
| Churchill, GC; Louis, CF | 1 |
| Mészáros, LG; Volpe, P; Zahradnikova, A | 1 |
| Parekh, AB | 1 |
| Fasolato, C; Pizzo, P; Pozzan, T | 1 |
| Bhattacharya, J; Chakrabarti, MK | 1 |
| Han, JK; Kim, MJ; Noh, SJ; Shim, S | 1 |
| Dale, B; De Simone, ML; Grumetto, L; Tosti, E; Wilding, M | 1 |
| Ambudkar, IS; Liu, X; Rojas, E | 1 |
| Chang, CH; Chang, TM; Chey, WY; Coy, DH; Erway, B | 1 |
| Behar, J; Biancani, P; Chen, Q; Harnett, K; Xiao, Z; Yu, P | 1 |
| Hussain, JF; Mahaut-Smith, MP | 1 |
| Akopian, A; Gabriel, R; Witkovsky, P | 1 |
| Ando, Y; Fowler, CJ; Tiger, G | 1 |
| Inoue, M; Nakayamada, H; Tokuyama, S; Ueda, H | 1 |
| Balla, T; Várnai, P | 1 |
| Artalejo, AR; Ellory, JC; Parekh, AB | 1 |
| Huang, Y; Putney, JW; Takahashi, M; Tanzawa, K | 1 |
| Hardie, RC; Raghu, P | 1 |
| Lee, SC; Lee, YH | 1 |
| Cahalan, MD; Kerschbaum, HH | 1 |
| Charpentier, G; Kado, RT | 1 |
| Fierro, L; Parekh, AB | 1 |
| Bender, M; Geiger, H; Gross, W; Herrero, M; Mondorf, UF; Olbrich, HG; Piiper, A; Scheuermann, E | 1 |
| Clapp, C; Díaz, M; Martinez de la Escalera, G; Trueta, C; Vaca, LA | 1 |
| Callewaert, G; De Smedt, H; De Smet, P; Missiaen, L; Parys, JB; Sipma, H; Vanlingen, S; Weidema, AF | 1 |
| Clapham, DE; Wang, H | 1 |
| Koshimizu, T; Stojilkovic, SS; Tomić, M; Van Goor, F; Yuan, D; Zivadinovic, D | 1 |
| Fogarty, KE; Kidd, JF; Thorn, P; Tuft, RA | 1 |
| Nakahata, N; Ohizumi, Y; Yaginuma, T | 1 |
| Shen, W; Slaughter, MM | 1 |
| Feijge, MA; Heemskerk, JW; Keularts, IM; van Gorp, RM; Vuist, WM | 1 |
| Cerione, RA; Hong-Geller, E | 1 |
| Bustamante, JO; Dean, DA; Geibel, JP; Hanover, JA; McDonnell, TJ; Michelette, ER | 1 |
| Glitsch, MD; Parekh, AB | 1 |
| Bradley, KN; Flynn, ER; McCarron, JG; Muir, TC | 1 |
| Brûle, G; Collin, T; Hague, F; Louvet, L; Matifat, F | 1 |
| Brearley, CA; Lemtiri-Chlieh, F; MacRobbie, EA | 1 |
| Callamaras, N; Parker, I | 1 |
| Akamatsu, N; Higaki, T; Imamura, H; Kawahara, T; Komatsu, S; Kono, Y; Nakagawa, M; Sato, T; Sawada, S; Tada, Y; Tamagaki, T; Toratani, A; Tsuda, Y; Tsuji, H; Yamasaki, S | 1 |
| Drummond, RM; Fay, FS; Gurney, AM | 1 |
| Barbara, JG; Lasser-Ross, N; Nakamura, K; Nakamura, T; Ross, WN; Sandler, VM | 1 |
| Bezprozvanny, I; Gusev, K; Kaznacheyeva, E; Mozhayeva, GN; Zubov, A | 1 |
| Biel, M; Droogmans, G; Flockerzi, V; Freichel, M; Freise, D; Hofmann, F; Nilius, B; Pfeifer, A; Philipp, S; Schweig, U; Suh, SH; Trost, C; Weissgerber, P | 1 |
| Leybaert, L; Sanderson, MJ | 1 |
| Bakowski, D; Gilabert, JA; Parekh, AB | 1 |
| Camacho, P; John, LM; Lechleiter, JD; Mosquera-Caro, M | 1 |
| Alvarez, J; Barrero, MJ; Lobatón, CD; Montero, M; Moreno, A; Torrecilla, F | 1 |
| Boetticher, E; Leff, AR; Muñoz, NM; Sano, A; Sano, H; Zhu, X | 1 |
| Ainscow, EK; Mitchell, KJ; Pinton, P; Pozzan, T; Rizzuto, R; Rutter, GA; Tacchetti, C; Varadi, A | 1 |
| Hirayama, T; Kawahara, T; Kurazono, H; Maeda, K; Mawatari, K; Moss, J; Nakaya, Y; Ogushi, K; Takahashi, A; Wada, A | 1 |
| Bödding, M | 1 |
| Raia, FJ; Valhmu, WB | 1 |
| Bödding, M; Flockerzi, V; Wissenbach, U | 1 |
| Fischer, JR; Fomin, VP; Gibbs, SG; Hurd, WW; Natarajan, V; Singh, DM | 1 |
| Darszon, A; De Blas, G; Mayorga, LS; Michaut, M; Tomes, CN; Treviño, CL; Yunes, R | 1 |
| Arai, H; Ashida, N; Kita, T; Takechi, H | 1 |
| Boni, R; Cuomo, A; Tosti, E | 1 |
| Lasater, EM; Vigh, J | 1 |
| Belton, CM; Fatherazi, S; Izutsu, KT | 1 |
| Caroppo, R; Colasuonno, A; Colella, M; Curci, S; Debellis, L; DeLuisi, A; Hofer, AM | 1 |
| Dargan, SL; Parker, I | 1 |
| Hoesch, RE; Kao, JP; Weinreich, D | 1 |
| Kanchiku, I; Kato, N; Kita, T; Takechi, H; Yamada, S | 1 |
| Bose, R; McNicol, A; Roberts, DE | 1 |
| Akhkha, A; Curtis, R; Kennedy, M; Kusel, J | 1 |
| Basset, O; Boittin, FX; Chatton, JY; Dorchies, OM; Ruegg, UT; van Breemen, C | 1 |
| Frieden, M; Graier, WF; Malli, R; Trenker, M | 1 |
| Alzayady, KJ; Wojcikiewicz, RJ | 1 |
| Ha, DC; Han, S; Kim, KT; Kim, TD | 1 |
| Cusato, K; Ripps, H; Spray, DC; Zakevicius, J | 1 |
| Deguchi, R; Kondoh, E; Tachibana, K | 1 |
| Levi, R; Selverston, AI | 1 |
| Banach, K; Kapur, N; Mignery, GA | 1 |
| Del Negro, CA; Feldman, JL; Mackay, DD; Pace, RW | 1 |
| Pan, HL; Wu, ZZ | 1 |
| Iwamoto, T; Katsuragi, T; Migita, K; Sato, C; Usune, S; Zhao, Y | 1 |
| Chung, DK; Gim, MG; Kim, HG; Kim, JY; Lee, JM | 1 |
| Friis, S; Mathes, C; Schrøder, RL; Sunesen, M; Willumsen, NJ | 1 |
| Parker, I; Smith, IF; Wiltgen, SM | 1 |
| Kang, JS; Kim, SJ; Kim, WK; Nam, JH; Shin, DH; Zheng, H | 1 |
| Adaramoye, OA; Medeiros, IA | 1 |
| Banumathi, E; Curtis, TM; Gurunathan, S; McGeown, JG; O'Connor, A; Simpson, DA | 1 |
| Brar, BK; Gayen, JR; Ghosh, S; Mahapatra, NR; Mahata, M; Mahata, SK; Nandi, S; O'Connor, DT; Taupenot, L; Zhang, K | 1 |
| Barella, M; Dawson, SP; Espada, R; Ponce, ML; Sigaut, L | 1 |
| Albarran, L; Berna-Erro, A; Dionisio, N; Hernandez-Cruz, JM; Rosado, JA; Salido, GM | 1 |
| Bouillet, LE; Brandão, RL; Cardoso, AS; Castro, IM; Fietto, LG; Martegani, E; Pereira, RR; Perovano, E; Ribeiro, EM; Tisi, R; Trópia, MJ | 1 |
| Alvarez, J; de la Fuente, S; Fonteriz, RI; Montero, M | 1 |
| Courjaret, R; Machaca, K | 1 |
| Piegari, E; Ponce Dawson, S; Sigaut, L | 1 |
| Jiao, P; Wang, H; Wang, L; Wang, ZK; Wang, ZY; Yang, DB; Zhou, XP | 1 |
| Biwer, LA; Hoehn, KL; Isakson, BE; Kenwood, BM; Straub, AC; Taddeo, EP | 1 |
2 review(s) available for egtazic acid and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Thyrotropin-releasing hormone action: mechanism of calcium-mediated stimulation of prolactin secretion.
Topics: Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Egtazic Acid; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Models, Biological; Phosphatidylinositols; Pituitary Gland; Prolactin; Thyrotropin-Releasing Hormone | 1985 |
A rapid decline in external Ca2+ induces Ca2+ mobilization in bovine adrenal glomerulosa cells.
Topics: Animals; Calcium; Calcium Radioisotopes; Cattle; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Rats; Zona Glomerulosa | 1988 |
265 other study(ies) available for egtazic acid and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Mechanism of release of Ca2+ from intracellular stores in response to ionomycin in oocytes of the frog Xenopus laevis.
Topics: Acetylcholine; Animals; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Female; GTP-Binding Proteins; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ionomycin; Membrane Potentials; Oocytes; Xenopus laevis | 1992 |
Reducing inositol lipid hydrolysis, Ins(1,4,5)P3 receptor availability, or Ca2+ gradients lengthens the duration of the cell cycle in Xenopus laevis blastomeres.
Topics: Animals; Antibodies, Monoclonal; Blastomeres; Calcium; Calcium Channels; Cell Cycle; Diglycerides; Egtazic Acid; Glycerol; Heparin; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Microinjections; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Type C Phospholipases; Xenopus laevis | 1992 |
Depletion of intracellular calcium stores activates a calcium current in mast cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; Cell Membrane Permeability; Cells, Cultured; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Ionomycin; Mast Cells; Membrane Potentials; Rats; Terpenes; Thapsigargin | 1992 |
Stimulation of adenosine A1 receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells.
Topics: Adenosine; Animals; Bradykinin; Calcium; Cell Line; Colforsin; Cricetinae; Drug Synergism; Egtazic Acid; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Kinetics; Leiomyosarcoma; Mesocricetus; Muscle, Smooth; Pertussis Toxin; Receptors, Bradykinin; Receptors, Neurotransmitter; Receptors, Purinergic; Virulence Factors, Bordetella | 1992 |
Effects of EGF on the mass of inositol 1,4,5-trisphosphate and SN(1,2)-diacylglycerol in freshly isolated rat hepatocytes: comparison with vasopressin.
Topics: Animals; Calcium; Chlorides; Diglycerides; Egtazic Acid; Enzyme Activation; Epidermal Growth Factor; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Lithium; Lithium Chloride; Liver; Protein Kinase C; Rats; Vasopressins | 1992 |
Luminal Ca2+ controls the activation of the inositol 1,4,5-trisphosphate receptor by cytosolic Ca2+.
Topics: Animals; Aorta; Calcium; Calcium Channels; Cell Line; Cell Membrane Permeability; Cytosol; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear | 1992 |
Feedback inhibition of Ca2+ release by Ca2+ is the underlying mechanism of agonist-evoked intracellular Ca2+ oscillations in pancreatic acinar cells.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Cholecystokinin; Egtazic Acid; Feedback; Fura-2; Inositol 1,4,5-Trisphosphate; Kinetics; Oscillometry; Pancreas; Peptide Fragments; Rats; Sincalide; Spectrometry, Fluorescence; Terpenes; Thapsigargin | 1992 |
Kinetics of intracellular calcium release by inositol 1,4,5-trisphosphate and extracellular ATP in porcine cultured aortic endothelial cells.
Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Aorta; Calcium; Cells, Cultured; Egtazic Acid; Endothelium, Vascular; Fluorescent Dyes; Inositol 1,4,5-Trisphosphate; Kinetics; Spectrometry, Fluorescence; Swine; Xanthenes | 1992 |
Cell physiology. Controls on calcium influx.
Topics: Animals; Calcium; Cell Membrane; Egtazic Acid; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Ion Channels; Ionomycin; Models, Biological | 1992 |
Abnormal Ca2+ homeostasis before cell death revealed by whole cell recording of ischemic CA1 hippocampal neurons.
Topics: Animals; Caffeine; Calcium; Cell Death; Egtazic Acid; Electric Stimulation; Gerbillinae; Hippocampus; Homeostasis; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ischemic Attack, Transient; Membrane Potentials; Nerve Fibers; Neurons; Organ Specificity; Pyramidal Tracts | 1992 |
In situ imaging of agonist-sensitive calcium pools in AR4-2J pancreatoma cells. Evidence for an agonist- and inositol 1,4,5-trisphosphate-sensitive calcium pool in or closely associated with the nuclear envelope.
Topics: Animals; Calcium; Cell Nucleus; Cytoplasm; Egtazic Acid; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate; Kinetics; Methacholine Chloride; Microscopy, Electron; Microscopy, Fluorescence; Mitochondria; Nuclear Envelope; Pancreatic Neoplasms; Rats; Terpenes; Thapsigargin; Time Factors; Tumor Cells, Cultured | 1992 |
Adaptation-promoting effect of IP3, Ca2+, and phorbol ester on the sugar taste receptor cell of the blowfly, Phormia regina.
Topics: Adaptation, Physiological; Animals; Calcium; Diptera; Egtazic Acid; Electrophysiology; Inositol 1,4,5-Trisphosphate; Models, Biological; Phorbol Esters; Sucrose; Taste; Taste Buds | 1992 |
Signal transduction by neutrophil immunoglobulin G Fc receptors. Dissociation of intracytoplasmic calcium concentration rise from inositol 1,4,5-trisphosphate.
Topics: Adult; Antigens, Differentiation; Calcium; Calcium-Transporting ATPases; Cytoplasm; Egtazic Acid; Humans; Immunoglobulin G; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Receptors, Fc; Receptors, IgG; Signal Transduction; Terpenes; Thapsigargin; Time Factors; Virulence Factors, Bordetella | 1992 |
Thrombin-induced Ca2+ mobilization in vascular smooth muscle utilizes a slowly ribosylating pertussis toxin-sensitive G protein. Evidence for the involvement of a G protein in inositol trisphosphate-dependent Ca2+ release.
Topics: Adenosine Diphosphate Ribose; Animals; Antioxidants; Autoradiography; Blotting, Western; Calcium; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Hydroquinones; Inositol 1,4,5-Trisphosphate; Lanthanum; Muscle, Smooth, Vascular; Pertussis Toxin; Rats; Terpenes; Thapsigargin; Thrombin; Virulence Factors, Bordetella | 1992 |
Disturbance of membrane function preceding ischemic delayed neuronal death in the gerbil hippocampus.
Topics: Animals; Calcium; Cell Death; Disease Models, Animal; Egtazic Acid; Gerbillinae; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Inositol 1,4,5-Trisphosphate; Ischemic Attack, Transient; Male; Membrane Potentials; Pyramidal Tracts; Reperfusion | 1992 |
Spontaneous cytosolic calcium oscillations driven by inositol trisphosphate occur during in vitro maturation of mouse oocytes.
Topics: Animals; Calcium; Cytosol; Egtazic Acid; Female; Heparin; Inositol 1,4,5-Trisphosphate; Meiosis; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nickel; Ovum | 1992 |
Role of inositol triphosphate isomer formation in type II pneumocyte signal transduction.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Cells, Cultured; Chlorides; Chromatography, High Pressure Liquid; Egtazic Acid; Fluorescent Dyes; Indoles; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Lithium; Lithium Chloride; Lung; Male; Rats; Signal Transduction | 1991 |
Cholecystokinin-induced phosphatidylinositol hydrolysis in rat pancreatic acinar cells: modulation by extracellular calcium and manganese.
Topics: Animals; Calcium; Cell Line; Diltiazem; Egtazic Acid; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lanthanum; Male; Manganese; Nifedipine; Pancreas; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Rats, Inbred Strains; Sincalide; Verapamil | 1991 |
Cell signalling associated with fibrinolytic ligand binding to human colorectal carcinoma cells.
Topics: Cell Communication; Colorectal Neoplasms; Egtazic Acid; Fibrinolysin; Fibrinolysis; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neoplasm Invasiveness; Nifedipine; Phosphatidylinositols; Plasminogen; Signal Transduction; Tumor Cells, Cultured | 1991 |
Effects of adenine nucleotides on inositol 1,4,5-trisphosphate-induced calcium release in vascular smooth muscle cells.
Topics: Adenine Nucleotides; Animals; Caffeine; Calcium; Calcium Channels; Edetic Acid; Egtazic Acid; Fluorometry; Fura-2; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Ionomycin; Muscle, Smooth, Vascular; Ryanodine; Time Factors | 1991 |
A serum factor that activates the phosphatidylinositol phosphate signaling system in Xenopus oocytes.
Topics: Animals; Blood; Cells, Cultured; Chloride Channels; Chlorides; Culture Media; Egtazic Acid; Female; Inositol 1,4,5-Trisphosphate; Ion Channels; Membrane Potentials; Membrane Proteins; Oocytes; Phosphatidylinositols; Rabbits; Second Messenger Systems; Serotonin; Signal Transduction; Species Specificity; Xenopus laevis | 1990 |
Correlation between plasma membrane potential and second messenger generation in the promyelocytic cell line HL-60.
Topics: Calcium; Cell Line; Cell Membrane; Cytosol; Dimethyl Sulfoxide; Egtazic Acid; Gramicidin; Humans; Inositol 1,4,5-Trisphosphate; Ionomycin; Kinetics; Leukemia, Promyelocytic, Acute; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Ouabain; Potassium Chloride; Second Messenger Systems; Tretinoin; Tumor Cells, Cultured | 1990 |
Evaluation of the role of inositol trisphosphate in IgE-dependent exocytosis.
Topics: Animals; Antigens; Calcium; Egtazic Acid; Exocytosis; Histamine Release; Immunoglobulin E; Inositol 1,4,5-Trisphosphate; Lithium; Mast Cells; Rats; Receptors, Immunologic; Serotonin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Correlates of aldosterone-induced increases in Cai2+ and Isc suggest that Cai2+ is the second messenger for stimulation of apical membrane conductance.
Topics: Aldosterone; Animals; Calcimycin; Calcium; Calmodulin; Cell Polarity; Clone Cells; Cycloheximide; Dactinomycin; Egtazic Acid; Electric Conductivity; Inositol 1,4,5-Trisphosphate; Kidney; Membrane Potentials; Protein Biosynthesis; Second Messenger Systems; Transcription, Genetic; Xenopus laevis | 1992 |
Agonist/inositol trisphosphate-induced release of calcium from murine keratinocytes: a possible link with keratinocyte differentiation.
Topics: Animals; Animals, Newborn; Calcitriol; Calcium; Cell Differentiation; Cells, Cultured; Egtazic Acid; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Keratinocytes; Kinetics; Mice; Mice, Inbred BALB C; Spectrometry, Fluorescence; Tretinoin | 1991 |
Involvement of cellular calcium incorporated from the medium in production of inositol trisphosphate in A-431 cells.
Topics: Adenosine Triphosphate; Calcimycin; Calcium; Culture Media; Egtazic Acid; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Tumor Cells, Cultured | 1991 |
Hormone-induced calcium oscillations in liver cells can be explained by a simple one pool model.
Topics: Animals; Benzimidazoles; Calcium; Calmodulin; Cells, Cultured; Egtazic Acid; Feedback; Fura-2; Imidazoles; Inositol 1,4,5-Trisphosphate; Kinetics; Liver; Male; Mathematics; Microscopy, Fluorescence; Models, Biological; Phenylephrine; Rats; Rats, Inbred Strains | 1991 |
Stimulation of Ca2+ influx by endothelin-1 is subject to negative feedback by elevated intracellular Ca2+.
Topics: Animals; Biological Transport; Calcium; Calcium Channel Blockers; Cell Line; Chelating Agents; Diglycerides; Egtazic Acid; Endothelins; Feedback; Inositol 1,4,5-Trisphosphate; Kinetics; Rats; Second Messenger Systems | 1991 |
Mobilization of calcium by inositol trisphosphates from permeabilized rat parotid acinar cells. Evidence for translocation of calcium from uptake to release sites within the inositol 1,4,5-trisphosphate- and thapsigargin-sensitive calcium pool.
Topics: Animals; Calcium; Cell Compartmentation; Cell Membrane Permeability; Cells, Cultured; Diphosphoglyceric Acids; Egtazic Acid; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Organelles; Parotid Gland; Rats; Terpenes; Thapsigargin; Time Factors | 1991 |
Propagation of transient Ca2+ increase in sea urchin eggs upon fertilization and its regulation by microinjecting EGTA solution.
Topics: Animals; Calcium; Cytoplasm; Egtazic Acid; Female; Fertilization; Fluorescence; Fura-2; Inositol 1,4,5-Trisphosphate; Microinjections; Microscopy; Ovum; Sea Urchins; Video Recording | 1991 |
Injection of inositol trisphosphorothioate into Limulus ventral photoreceptors causes oscillations of free cytosolic calcium.
Topics: Animals; Calcium; Cytosol; Egtazic Acid; Horseshoe Crabs; Injections; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Photoreceptor Cells | 1991 |
Endotoxic lipid A induces intracellular Ca2+ increase in human platelets.
Topics: Blood Platelets; Calcium; Egtazic Acid; Enzyme Activation; Fluorescent Dyes; Fura-2; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lipid A; Manganese; Nickel; Protein Kinase C | 1991 |
Cellular mechanism of endothelin-1 release by angiotensin and vasopressin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cattle; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Endothelins; Endothelium, Vascular; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Neomycin; Nicardipine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine | 1991 |
Spontaneous [Ca2+]i fluctuations in rat chromaffin cells do not require inositol 1,4,5-trisphosphate elevations but are generated by a caffeine- and ryanodine-sensitive intracellular Ca2+ store.
Topics: Adrenal Medulla; Alkaloids; Bradykinin; Caffeine; Calcium; Egtazic Acid; Histamine; Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Potentials; Neomycin; Nitrendipine; Ryanodine; Spectrometry, Fluorescence | 1990 |
Raising the intracellular level of inositol 1,4,5-trisphosphate changes plasma membrane ion transport in characean algae.
Topics: Calcium; Cell Membrane Permeability; Cytoplasm; Egtazic Acid; Eukaryota; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Plants | 1990 |
Calcium free inositol (1,4,5)-trisphosphate stimulates protein kinase C dependent protein phosphorylation in nuclei isolated from mitogen-treated Swiss 3T3 cells.
Topics: Animals; Bombesin; Brain; Calcium; Cell Line; Cell Nucleus; Egtazic Acid; Histones; Inositol 1,4,5-Trisphosphate; Insulin-Like Growth Factor I; Kinetics; Mice; Molecular Weight; Nuclear Proteins; Phosphorylation; Protein Kinase C; Rats | 1990 |
Receptor-linked early events induced by vasoactive intestinal contractor (VIC) on neuroblastoma and vascular smooth-muscle cells.
Topics: Animals; Calcium; Cell Line; Cells, Cultured; Choline; Diglycerides; Egtazic Acid; Fura-2; Inositol 1,4,5-Trisphosphate; Intercellular Signaling Peptides and Proteins; Kinetics; Muscle, Smooth, Vascular; Myristic Acid; Myristic Acids; Neuroblastoma; Nifedipine; Palmitic Acid; Palmitic Acids; Peptides | 1990 |
Regulation of calcium influx across the plasma membrane of the human T-leukemic cell line, JURKAT: dependence on a rise in cytosolic free calcium can be dissociated from formation of inositol phosphates.
Topics: Aminoquinolines; Antibodies, Monoclonal; Benzofurans; Calcium; Calcium Channels; Cell Membrane; Chromatography, Ion Exchange; Cytosol; Egtazic Acid; Fluorescent Dyes; Fura-2; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Leukemia, T-Cell; Manganese; Phytohemagglutinins; Second Messenger Systems; Spectrometry, Fluorescence; Tumor Cells, Cultured | 1990 |
Endothelin receptor-coupling mechanisms in vascular smooth muscle: a role for protein kinase C.
Topics: Alkaloids; Animals; Calcium; Cells, Cultured; Diglycerides; Drug Interactions; Egtazic Acid; Endothelins; Inositol 1,4,5-Trisphosphate; Muscle, Smooth, Vascular; Peptides; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, Endothelin; Staurosporine; Vasoconstriction; Vasoconstrictor Agents | 1990 |
Phosphoinositide metabolism in intestinal brush borders: stimulation of IP3 formation by guanine nucleotides and Ca2+.
Topics: Adenosine Triphosphate; Animals; Calcium; Egtazic Acid; Epithelium; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Jejunum; Kinetics; Male; Membrane Lipids; Microvilli; Muscle, Smooth; Phosphatidylinositols; Rats; Rats, Inbred Strains; Thionucleotides | 1990 |
Auranofin dissociates chemotactic peptide-induced generation of inositol 1,4,5-trisphosphate from the subsequent mobilization of intracellular calcium in intact human neutrophils.
Topics: Aminoquinolines; Auranofin; Calcium; Calcium Channels; Egtazic Acid; Fluorescent Dyes; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear | 1990 |
Does cyclic AMP mobilize Ca2+ for amylase secretion from rat parotid cells?
Topics: Amylases; Animals; Bucladesine; Calcimycin; Calcium; Carbachol; Cell Membrane Permeability; Cyclic AMP; Egtazic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Parotid Gland; Rats; Rats, Inbred Strains; Saponins | 1986 |
Ionic mechanism of the outward current induced by intracellular injection of inositol trisphosphate into Aplysia neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aplysia; Calcium; Chlorides; Egtazic Acid; Electric Conductivity; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ion Channels; Membrane Potentials; Neurons; Potassium; Sugar Phosphates; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Neurotensin and acetylcholine evoke common responses in frog oocytes injected with rat brain messenger ribonucleic acid.
Topics: Acetylcholine; Action Potentials; Animals; Brain; Egtazic Acid; Female; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neurotensin; Oocytes; Pertussis Toxin; Poly A; Rats; RNA, Messenger; Substance P; Time Factors; Virulence Factors, Bordetella; Xenopus laevis | 1987 |
Regulation of calcium influx by second messengers in rat mast cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Chlorides; Cyclic AMP; Egtazic Acid; Electric Conductivity; Exocytosis; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ion Channels; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Rats; Substance P; Sugar Phosphates; Thionucleotides | 1988 |
Early effects of parathyroid hormone on membrane potential of rat osteoblasts in culture: role of cAMP and Ca2+.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Cobalt; Colforsin; Cyclic AMP; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Membrane Potentials; Microelectrodes; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Rats; Second Messenger Systems | 1988 |
Photochemically generated cytosolic calcium pulses and their detection by fluo-3.
Topics: Aniline Compounds; Animals; Benzofurans; Calcium; Cell Line; Chelating Agents; Cytosol; Digitonin; Egtazic Acid; Fibroblasts; Fluorescent Dyes; Fura-2; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Manganese; Microscopy, Fluorescence; Photolysis; Rats; Signal Transduction; Spectrometry, Fluorescence; T-Lymphocytes; Tumor Cells, Cultured; Xanthenes; Zinc | 1989 |
Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration.
Topics: Acetylcholine; Animals; Calcium; Egtazic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Mice; Pancreas; Second Messenger Systems; Sugar Phosphates | 1989 |
Cytosolic heparin inhibits muscarinic and alpha-adrenergic Ca2+ release in smooth muscle. Physiological role of inositol 1,4,5-trisphosphate in pharmacomechanical coupling.
Topics: Animals; Caffeine; Carbachol; Cytosol; Egtazic Acid; Guinea Pigs; Heparin; Ileum; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isometric Contraction; Kinetics; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Pulmonary Artery; Ryanodine | 1989 |
Dissociation of Ca2+ entry and Ca2+ mobilization responses to angiotensin II in bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Angiotensin II; Animals; Calcium; Calcium Radioisotopes; Cations, Divalent; Cattle; Chlorides; Chromaffin System; Egtazic Acid; Extracellular Space; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ionomycin; Lanthanum; Manganese; Manganese Compounds; Spectrometry, Fluorescence | 1989 |
A metabolically stable analog of 1,4,5-inositol trisphosphate activates a novel K+ conductance in pyramidal cells of the rat hippocampal slice.
Topics: Action Potentials; Animals; Barium; Calcium; Egtazic Acid; Electric Conductivity; Electrophysiology; Hippocampus; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Male; Organothiophosphorus Compounds; Potassium; Rats; Reaction Time | 1989 |
Reinforcement of signal generation at B2 bradykinin receptors by insulin, epidermal growth factors, and other growth factors.
Topics: Adrenal Gland Neoplasms; Animals; Bradykinin; Calcium; Calcium Channels; Cell Division; Egtazic Acid; Epidermal Growth Factor; ErbB Receptors; Growth Substances; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Insulin; Insulin-Like Growth Factor I; Kinetics; Neuroblastoma; Pheochromocytoma; Phosphatidylinositol Phosphates; Phosphatidylinositols; Rats; Receptors, Bradykinin; Receptors, Neurotransmitter; Signal Transduction; Transforming Growth Factors; Tumor Cells, Cultured | 1989 |
Alpha 1-adrenergic inositol trisphosphate production in brown adipocytes is Na+ dependent.
Topics: Adipose Tissue, Brown; Animals; Cells, Cultured; Cricetinae; Egtazic Acid; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lithium; Mesocricetus; Norepinephrine; Oxygen Consumption; Receptors, Adrenergic, alpha; Sodium; Sugar Phosphates | 1987 |
Epidermal growth factor-induced increases in inositol trisphosphates, inositol tetrakisphosphates, and cytosolic Ca2+ in a human hepatocellular carcinoma-derived cell line.
Topics: Calcium; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Cytosol; Egtazic Acid; Epidermal Growth Factor; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver Neoplasms; Sugar Phosphates; Tumor Cells, Cultured | 1988 |
Plasma from uninephrectomized rats stimulates production of inositol trisphosphates and inositol tetrakisphosphate in renal cortical slices.
Topics: Animals; Blood; Chromatography, High Pressure Liquid; Cyclic AMP; Cyclic GMP; Egtazic Acid; Female; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kidney Cortex; Nephrectomy; Rats; Rats, Inbred Strains; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1988 |
Inositol (1,4,5)-trisphosphate activates a calcium channel in isolated sarcoplasmic reticulum membranes.
Topics: Animals; Anura; Calcium; Calcium Channels; Egtazic Acid; Electric Conductivity; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lipid Bilayers; Muscles; Sarcoplasmic Reticulum; Sugar Phosphates | 1988 |
Inositol 1,4,5-trisphosphate releases Ca2+ from vacuolar membrane vesicles of oat roots.
Topics: Calcium; Calcium Channel Blockers; Edible Grain; Egtazic Acid; Gallic Acid; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Membranes; Organoids; Plants; Proton-Translocating ATPases; Sugar Phosphates; Vacuoles | 1987 |
Calcium homeostasis in digitonin-permeabilized bovine chromaffin cells.
Topics: Acetylcholine; Adenosine Triphosphate; Adrenal Glands; Animals; Calcimycin; Calcium; Calcium Radioisotopes; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Cell Membrane Permeability; Chromaffin System; Cytosol; Digitonin; Egtazic Acid; Glutamates; Glutamic Acid; Homeostasis; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Vanadates | 1988 |
Beta-adrenergic receptor stimulation induces inositol trisphosphate production and Ca2+ mobilization in rat parotid acinar cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Antagonists; Animals; Atenolol; Calcium; Carbachol; Cyclic AMP; Cytosol; Egtazic Acid; Enkephalins; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoproterenol; Male; Parotid Gland; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Propanolamines; Propranolol; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sugar Phosphates | 1988 |
Inositol trisphosphate-induced Ca2+ release from rat parotid subcellular fractions.
Topics: Animals; Calcium; Culture Media; Egtazic Acid; Endoplasmic Reticulum; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Microsomes; Parotid Gland; Rats; Subcellular Fractions; Sugar Phosphates | 1986 |
Inositol trisphosphate isomers, but not inositol 1,3,4,5-tetrakisphosphate, induce calcium influx in Xenopus laevis oocytes.
Topics: Animals; Calcium; Chlorides; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Oocytes; Sugar Phosphates; Xenopus laevis | 1988 |
Inositol trisphosphate enhances calcium release in skinned cardiac and skeletal muscle.
Topics: Animals; Caffeine; Calcium; Egtazic Acid; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Muscle Contraction; Muscles; Papillary Muscles; Rana pipiens; Sarcoplasmic Reticulum; Sugar Phosphates | 1986 |
Epidermal growth factor stimulates the rapid accumulation of inositol (1,4,5)-trisphosphate and a rise in cytosolic calcium mobilized from intracellular stores in A431 cells.
Topics: Bradykinin; Calcium; Carcinoma, Squamous Cell; Cell Line; Chromatography, High Pressure Liquid; Cytosol; Egtazic Acid; Epidermal Growth Factor; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Sugar Phosphates | 1987 |
Translational control of InsP3-induced chromatin condensation during the early cell cycles of sea urchin embryos.
Topics: Animals; Calcium; Cell Cycle; Chromatin; Egtazic Acid; Emetine; Ethylenediamines; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Protein Biosynthesis; Sea Urchins; Sugar Phosphates | 1988 |
Initial and sustained calcium mobilizations in the parietal cell during stimulations with gastrin, inositol trisphosphate, phorbol ester and exogenous diacylglycerol.
Topics: Adenosine Triphosphate; Aequorin; Animals; Benzofurans; Calcimycin; Calcium; Calcium Radioisotopes; Cytoplasm; Diglycerides; Egtazic Acid; Electron Probe Microanalysis; Fluorescent Dyes; Fura-2; Gastrins; Glycerides; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Parietal Cells, Gastric; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1988 |
Inositol 1,4,5-trisphosphate alters bursting pacemaker activity in Aplysia neurons: voltage-clamp analysis of effects on calcium currents.
Topics: Action Potentials; Animals; Aplysia; Calcium; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Membrane Potentials; Neurons; Potassium; Sugar Phosphates; Tetraethylammonium Compounds | 1988 |
The influence of intracellular calcium concentration on degranulation of dialysed mast cells from rat peritoneum.
Topics: Action Potentials; Animals; Calcium; Cytoplasmic Granules; Dialysis; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mast Cells; Peritoneal Cavity; Rats; Thionucleotides; Time Factors | 1988 |
Generation of inositol phosphates, cytosolic Ca2+, and ionic fluxes in PC12 cells treated with bradykinin.
Topics: Adrenal Gland Neoplasms; Animals; Benzofurans; Bradykinin; Calcium; Cell Line; Cell Membrane; Cytosol; Egtazic Acid; Fura-2; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Membrane Potentials; Pheochromocytoma; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1988 |
Inositol 1,4,5-triphosphate microinjection triggers activation, but not meiotic maturation in amphibian and starfish oocytes.
Topics: Adenine; Animals; Egtazic Acid; Exocytosis; Female; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Meiosis; Microinjections; Oocytes; Progesterone; Starfish; Sugar Phosphates; Xenopus laevis | 1985 |
A role for inositol triphosphate in intracellular Ca2+ mobilization and granule secretion in platelets.
Topics: Adenosine Triphosphate; Blood Platelets; Calcium; Cell Membrane Permeability; Cytoplasmic Granules; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Magnesium; Saponins; Serotonin; Sodium; Sugar Phosphates; Time Factors | 1985 |
Inositol trisphosphate activates pyruvate dehydrogenase in isolated fat cells.
Topics: Adipose Tissue; Animals; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Pyruvate Dehydrogenase Complex; Rats; Sugar Phosphates | 1984 |
myo-Inositol 1,4,5-trisphosphate stimulates protein phosphorylation in saponin-permeabilized human platelets.
Topics: Blood Platelets; Blood Proteins; Calcium; Cell Membrane Permeability; Egtazic Acid; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Phosphorylation; Saponins; Sugar Phosphates | 1984 |
Eclosion hormone-mediated signal transduction in the silkworm abdominal ganglia: involvement of a cascade from inositol(1,4,5)trisphosphate to cyclic GMP.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bombyx; Calcium; Citrulline; Cyclic GMP; Egtazic Acid; Enzyme Activation; Ganglia, Invertebrate; Inositol 1,4,5-Trisphosphate; Insect Hormones; Neomycin; Nitric Oxide Synthase; Nitroarginine; p-Methoxy-N-methylphenethylamine; Second Messenger Systems; Signal Transduction; Sulfonamides | 1994 |
Flash photolysis studies of the localization of calcium release sites in rat parotid isolated acinar cells.
Topics: Animals; Calcium; Carbachol; Cell Membrane; Chelating Agents; Egtazic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ion Channels; Muscarinic Agonists; Parotid Gland; Patch-Clamp Techniques; Photolysis; Rats; Receptors, Muscarinic; Ultraviolet Rays | 1994 |
CCK-8-evoked cationic currents in substantia nigra dopaminergic neurons are mediated by InsP3-induced Ca2+ release.
Topics: Alkaloids; Animals; Calcium; Calcium Channels; Dopamine; Egtazic Acid; Evoked Potentials; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ion Channels; Neurons; Peptide Fragments; Pertussis Toxin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sincalide; Staurosporine; Substantia Nigra; Thionucleotides; Time Factors; Virulence Factors, Bordetella | 1994 |
CPA enhances Ca2+ entry in cultured bovine pulmonary arterial endothelial cells in an IP3-independent manner.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cattle; Cells, Cultured; Charybdotoxin; Egtazic Acid; Endothelium, Vascular; Evoked Potentials; Indoles; Inositol 1,4,5-Trisphosphate; Kinetics; Nitric Oxide; Potassium Channels; Pulmonary Artery; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1995 |
Luminal calcium regulates the inositol trisphosphate receptor of rat basophilic leukemia cells at a cytosolic site.
Topics: Animals; Calcium; Calcium Channels; Cytosol; Egtazic Acid; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Leukemia, Basophilic, Acute; Rats; Receptors, Cytoplasmic and Nuclear; Tumor Cells, Cultured | 1995 |
Effects of bradykinin on Ca2+ mobilization and prostaglandin E2 release in human periodontal ligament cells.
Topics: 4-Nitrophenylphosphatase; Alkaline Phosphatase; Animals; Bradykinin; Calcium; Cells, Cultured; Chelating Agents; Dinoprostone; Egtazic Acid; Fluorescent Dyes; Fura-2; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Ligaments; Osteocalcin; Periodontium; Rats; RNA, Messenger; Time Factors | 1995 |
Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells.
Topics: Acetylcholine; Atropine; Calcium; Egtazic Acid; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lithium Chloride; Neuroblastoma; Nickel; Receptors, Muscarinic; Second Messenger Systems; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
The release of intracellular Ca2+ in lacrimal acinar cells by alpha-, beta-adrenergic and muscarinic cholinergic stimulation: the roles of inositol triphosphate and cyclic ADP-ribose.
Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Calcium; Cyclic ADP-Ribose; Egtazic Acid; Epinephrine; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Isoproterenol; Lacrimal Apparatus; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Muscarinic; Ryanodine; Signal Transduction | 1995 |
Evidence for stimulation of the inositol triphosphate-Ca2+ signalling system in rat enterocytes by heat stable enterotoxin of Escherichia coli.
Topics: Animals; Calcium; Egtazic Acid; Enterotoxins; Escherichia coli; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Jejunum; Rats; Signal Transduction | 1995 |
Inhibitors of ER Ca(2+)-ATPase activity deplete the ATP- and thrombin-sensitive Ca2+ pool in UMR 106-01 osteosarcoma cells.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Bone Neoplasms; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cell Membrane Permeability; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Fura-2; Hydroquinones; Inositol 1,4,5-Trisphosphate; Nifedipine; Osteoblasts; Osteosarcoma; Terpenes; Thapsigargin; Thrombin; Tumor Cells, Cultured | 1995 |
Depletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Alkaloids; Animals; Calcium; Calcium Channels; Cell Line; Dialysis; Egtazic Acid; Fura-2; Homeostasis; Indoles; Inositol 1,4,5-Trisphosphate; Kinetics; Leukemia, Basophilic, Acute; Maleimides; Patch-Clamp Techniques; Protein Kinase C; Protein Kinases; Rats; Receptors, Purinergic P1; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Stimulation and binding of myocardial phospholipase C by phosphatidic acid.
Topics: Animals; Cattle; Chromatography, Gel; Drug Resistance; Egtazic Acid; Female; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Isoenzymes; Lipids; Male; Myocardium; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylserines; Rabbits; Type C Phospholipases | 1995 |
Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alkaloids; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Cyclic AMP; Cytoplasm; Egtazic Acid; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Megakaryocytes; Models, Biological; Oscillometry; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1993 |
The sperm-induced Ca2+ wave following fertilization of the Xenopus egg requires the production of Ins(1, 4, 5)P3.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Egtazic Acid; Female; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Male; Procaine; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Ruthenium Red; Ryanodine; Sperm-Ovum Interactions; Xenopus laevis | 1993 |
Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Astrocytoma; Bradykinin; Brain Neoplasms; Calcimycin; Calcium; Calmodulin; Colforsin; Cyclic AMP; Dopamine; Egtazic Acid; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Neoplasm Proteins; Pyrrolidinones; Rolipram; Signal Transduction; Tumor Cells, Cultured | 1993 |
Substance P-induced elevation of intracellular calcium in transfected Chinese hamster ovary cells: role of inositol trisphosphate.
Topics: Animals; Calcium; Calcium Channels; CHO Cells; Cricetinae; DNA; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Membrane Potentials; Receptors, Neurokinin-1; Recombinant Proteins; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Transfection | 1993 |
Participation of calcium, released from the IP3-sensitive Ca-store in activation of Ca-dependent potassium conductance of ileal smooth muscle cells.
Topics: Animals; Apamin; Calcium; Charybdotoxin; Egtazic Acid; Glyburide; Guinea Pigs; Heparin; Ileum; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Muscle, Smooth; Nifedipine; Potassium Channels; Ruthenium Red; Scorpion Venoms | 1993 |
Inositol trisphosphate-dependent and -independent Ca2+ mobilization pathways at the vacuolar membrane of Candida albicans.
Topics: Anti-Bacterial Agents; Calcium; Candida albicans; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Egtazic Acid; Heparin; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Membranes; Kinetics; Macrolides; Manganese; Onium Compounds; Proton-Translocating ATPases; Spheroplasts; Trityl Compounds; Vacuoles; Verapamil | 1995 |
ATP causes release of intracellular Ca2+ via the phospholipase C beta/IP3 pathway in astrocytes from the dorsal spinal cord.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Astrocytes; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Egtazic Acid; Estrenes; Fetus; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoenzymes; Patch-Clamp Techniques; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Spinal Cord; Terpenes; Thapsigargin; Thionucleotides; Time Factors; Type C Phospholipases | 1995 |
The lifetime of inositol 1,4,5-trisphosphate in single cells.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Cell Differentiation; Egtazic Acid; Eukaryotic Cells; Feedback; Fura-2; Half-Life; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Neuroblastoma; Tumor Cells, Cultured | 1995 |
Inositol 1,4,5-trisphosphate formation and ryanodine-sensitive oscillations of cytosolic free Ca2+ concentrations in neuroblastoma x fibroblast hybrid NL308 cells expressing m2 and m4 muscarinic acetylcholine receptor subtypes.
Topics: Acetylcholine; Animals; Calcium; Cytosol; Egtazic Acid; Fibroblasts; Fluorometry; Fura-2; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Mice; Neuroblastoma; Pertussis Toxin; Radioligand Assay; Receptors, Muscarinic; Ryanodine; Transfection; Type C Phospholipases; Virulence Factors, Bordetella | 1995 |
Influence of the muscarinic agonist carbachol on intracellular Ca2+ in chicken granulosa cells: I. Dependence on follicular maturation.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Chickens; Egtazic Acid; Female; Granulosa Cells; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Manganese; Ovarian Follicle | 1995 |
The control of chloride conductance in rat parotid isolated acinar cells investigated by photorelease of caged compounds.
Topics: Adrenergic Agonists; Animals; Cell Separation; Chelating Agents; Chlorides; Egtazic Acid; Electric Conductivity; Inositol 1,4,5-Trisphosphate; Light; Male; Parotid Gland; Rats; Rats, Wistar; Receptors, Muscarinic | 1994 |
Calcium entry activated by store depletion in human umbilical vein endothelial cells.
Topics: Calcium; Calcium-Transporting ATPases; Chloride Channels; Egtazic Acid; Endothelium, Vascular; Humans; Inositol 1,4,5-Trisphosphate; Ion Transport; Membrane Potentials; Nitrobenzoates; Patch-Clamp Techniques; Terpenes; Thapsigargin; Umbilical Veins | 1994 |
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+.
Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Cell Line; Cytosol; Drug Synergism; Egtazic Acid; Embryo, Mammalian; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Magnesium; Muscle, Smooth, Vascular; Rats | 1995 |
Photoreleased inositol 1,4,5-trisphosphate-induced response in single smooth muscle cells of rat portal vein.
Topics: Animals; Caffeine; Calcium; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Heparin; Inositol 1,4,5-Trisphosphate; Light; Muscle, Smooth, Vascular; Photolysis; Portal Vein; Potassium Channels; Rats; Rats, Wistar; Time Factors | 1994 |
Inositol 1,3,4,5-tetrakisphosphate as a mediator of neuronal death in ischemic hippocampus.
Topics: Animals; Antibodies; Cell Death; Egtazic Acid; Evoked Potentials; Gerbillinae; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ischemic Attack, Transient; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Prosencephalon; Pyramidal Cells; Synapses | 1994 |
Effect of prostaglandin F2 alpha on Ca2+ influx in osteoblast-like cells: function of tyrosine kinase.
Topics: Calcium; Cell Line; Dinoprost; Dose-Response Relationship, Drug; Egtazic Acid; Genistein; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoflavones; Osteoblasts; Pertussis Toxin; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Vanadates; Virulence Factors, Bordetella | 1994 |
The role of inositol trisphosphate on ACh-induced outward currents in bullfrog saccular hair cells.
Topics: Acetylcholine; Animals; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Electric Conductivity; Guanosine 5'-O-(3-Thiotriphosphate); Hair Cells, Auditory; Heparin; Inositol 1,4,5-Trisphosphate; Lithium; Parasympatholytics; Parasympathomimetics; Potassium; Potassium Channels; Rana catesbeiana; Saccule and Utricle | 1994 |
Intracellular mechanisms involved in D-glucose-mediated amplification of agonist-induced Ca2+ response and EDRF formation in vascular endothelial cells.
Topics: Animals; Aorta; Bradykinin; Calcium; Calcium Radioisotopes; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; Egtazic Acid; Endothelium, Vascular; Glucose; Inositol 1,4,5-Trisphosphate; Manganese; Nitric Oxide; Potassium Chloride; Swine | 1994 |
Calcium and inositol 1,4,5-trisphosphate-induced Ca2+ release.
Topics: Animals; Calcium; Egtazic Acid; Feedback; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Sheep | 1994 |
Lithium-induced decrease in spontaneous Ca2+ oscillations in single GH3 rat pituitary cells.
Topics: Animals; Calcium; Cell Line; Egtazic Acid; Image Processing, Computer-Assisted; Inositol 1,4,5-Trisphosphate; Lithium; Pituitary Gland; Prolactin; Rats; Thyrotropin-Releasing Hormone | 1994 |
Protein kinase C-dependent and independent events in mouse egg activation.
Topics: Acridine Orange; Animals; Calcium; Cell Membrane; Cell Nucleus; Cytoplasmic Granules; Diglycerides; Egtazic Acid; Exocytosis; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ion Transport; Mice; Ovum; Protein Kinase C; Sphingosine | 1993 |
Sperm increase inositol 1,4,5-trisphosphate mass in Xenopus laevis eggs preinjected with calcium buffers or heparin.
Topics: Animals; Buffers; Calcium; Chelating Agents; Egtazic Acid; Female; Fertilization; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Ovum; Sperm-Ovum Interactions; Spermatozoa; Xenopus laevis | 1994 |
Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Bradykinin; Calcium; Calcium-Transporting ATPases; Cytosol; DNA; Egtazic Acid; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Kinetics; Lysophospholipids; Mice; Phorbol Esters; Second Messenger Systems; Sphingosine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1994 |
Muscarinic receptor activation down-regulates the type I inositol 1,4,5-trisphosphate receptor by accelerating its degradation.
Topics: Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Cell Line; CHO Cells; Cricetinae; Down-Regulation; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Neuroblastoma; Phosphatidylinositols; Phosphorylation; Receptors, Cytoplasmic and Nuclear; Receptors, Muscarinic; RNA, Messenger; Terpenes; Thapsigargin; Transfection; Tumor Cells, Cultured | 1994 |
Intracellular Ca2+, inositol 1,4,5-trisphosphate and additional signalling in the stimulation by platelet-activating factor of prostaglandin E2 formation in P388D1 macrophage-like cells.
Topics: Calcium; Cell Line; Dinoprostone; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Ionomycin; Lipopolysaccharides; Macrophages; Pertussis Toxin; Platelet Activating Factor; Protein-Tyrosine Kinases; Signal Transduction; Virulence Factors, Bordetella | 1994 |
Signal transduction in human epithelial cells infected with attaching and effacing Escherichia coli in vitro.
Topics: Bacterial Adhesion; Calcium; Cell Line; Egtazic Acid; Epithelial Cells; Epithelium; Escherichia coli; Escherichia coli Infections; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Microscopy, Electron; Oxalates; Phenotype; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Signal Transduction; Spectrometry, Fluorescence | 1994 |
Calcium signaling induced by bradykinin is synergistically enhanced by high K+ in NG108-15 cells.
Topics: Bradykinin; Calcium; Drug Synergism; Egtazic Acid; Extracellular Space; Glioma; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Ionomycin; Neuroblastoma; Osmolar Concentration; Potassium; Signal Transduction; Tumor Cells, Cultured | 1994 |
Muscarinic receptor-mediated inositol 1,4,5-trisphosphate formation in SH-SY5Y neuroblastoma cells is regulated acutely by cytosolic Ca2+ and by rapid desensitization.
Topics: Calcium; Calcium Channels; Calcium-Transporting ATPases; Cytosol; Egtazic Acid; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate; Neuroblastoma; Nickel; Phosphatidylinositols; Receptors, Muscarinic; Terpenes; Thapsigargin; Tumor Cells, Cultured | 1994 |
Loading dependence of inositol 1,4,5-trisphosphate-induced Ca2+ release in the clonal cell line A7r5. Implications for the mechanism of quantal Ca2+ release.
Topics: Animals; Binding Sites; Calcium; Cell Line; Clone Cells; Cytosol; Egtazic Acid; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Rats | 1993 |
Vectorial Ca2+ flux from the extracellular space to the endoplasmic reticulum via a restricted cytoplasmic compartment regulates inositol 1,4,5-trisphosphate-stimulated Ca2+ release from internal stores in vascular endothelial cells.
Topics: Animals; Biological Transport; Bradykinin; Calcium; Calcium-Transporting ATPases; Cattle; Cell Compartmentation; Cells, Cultured; Cytoplasm; Egtazic Acid; Endoplasmic Reticulum; Endothelium, Vascular; Extracellular Space; Humans; Hydroquinones; Imidazoles; Inositol 1,4,5-Trisphosphate; Terpenes; Thapsigargin | 1993 |
Phospholipase C in Dictyostelium discoideum. Cyclic AMP surface receptor and G-protein-regulated activity in vitro.
Topics: Animals; Calcium; Cyclic AMP; Dictyostelium; Egtazic Acid; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphatidylinositols; Receptors, Cyclic AMP; Thionucleotides; Tritium; Type C Phospholipases | 1994 |
Multiple mechanisms of manganese-induced quenching of fura-2 fluorescence in rat mast cells.
Topics: Animals; Calcium; Egtazic Acid; Electric Conductivity; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate; Male; Manganese; Mast Cells; Membrane Potentials; Rats; Rats, Wistar; Spectrometry, Fluorescence | 1993 |
Botulinum ADP-ribosyltransferase C3 induces elevation of the vitelline coat of ascidian eggs.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcimycin; Egtazic Acid; Female; Fertilization; Inositol 1,4,5-Trisphosphate; Membrane Proteins; Microinjections; Molecular Weight; Ovum; Urochordata; Vitelline Membrane | 1993 |
Intracellular injection of heparin and polyamines. Effects on phototransduction in limulus ventral photoreceptors.
Topics: Action Potentials; Animals; Arsenazo III; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Heparin; Horseshoe Crabs; Inositol 1,4,5-Trisphosphate; Light; Microelectrodes; Microinjections; Neomycin; Photoreceptor Cells; Polyamines; Spermine; Type C Phospholipases | 1993 |
Inositol trisphosphate-independent agonist-stimulated calcium influx in rat pancreatic acinar cells.
Topics: Animals; Calcium; Ceruletide; Egtazic Acid; Fura-2; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Manganese; Pancreas; Rats; Sincalide; Spectrometry, Fluorescence | 1993 |
Endothelin-mediated calcium response and inositol 1,4,5-trisphosphate release in neuroblastoma-glioma hybrid cells (NG108-15): cross talk with ATP and bradykinin.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Calcium Channels; Egtazic Acid; Endothelins; Fura-2; Glioma; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Neuroblastoma; Phosphatidylinositol Phosphates; Phosphatidylinositols; Radioligand Assay; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Time Factors | 1993 |
Coupling of the expressed alpha 1B-adrenergic receptor to the phospholipase C pathway in Xenopus oocytes. The role of Go.
Topics: Animals; Cattle; Egtazic Acid; Female; GTP-Binding Proteins; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Oocytes; Pertussis Toxin; Receptors, Adrenergic, alpha; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella; Xenopus laevis | 1993 |
Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of inositol 1,4,5-trisphosphate production.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Cyclic GMP; Egtazic Acid; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Protein Kinases; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Thrombin; Transfection | 1993 |
Inositol 1,4,5-trisphosphate mediates adrenaline activation of K+ conductance in mouse peritoneal macrophages.
Topics: Animals; Calcium; Egtazic Acid; Electric Conductivity; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Macrophages; Mice; Peritoneal Cavity; Potassium; Potassium Channels; Receptors, Adrenergic, alpha; Thionucleotides | 1993 |
Ca(2+)-dependent kinase and phosphatase control inositol 1,4,5-trisphosphate-mediated Ca2+ release. Modification by agonist stimulation.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Kinetics; Magnesium; Mice; Phosphoprotein Phosphatases; Protein Kinases | 1993 |
Effects of Ca2+ chelators on purified inositol 1,4,5-trisphosphate (InsP3) receptors and InsP3-stimulated Ca2+ mobilization.
Topics: Animals; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cerebellum; Chelating Agents; Chromatography, Affinity; Edetic Acid; Egtazic Acid; Fura-2; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Liver; Male; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear | 1993 |
Calcium mobilization is required for nuclear vesicle fusion in vitro: implications for membrane traffic and IP3 receptor function.
Topics: Animals; Calcium; Calcium Channels; Cytosol; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Membranes; Male; Membrane Fusion; Nuclear Envelope; Ovum; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Spermatozoa; Xenopus | 1993 |
Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.
Topics: Calcium; Calcium Channels; Egtazic Acid; Humans; Inositol 1,4,5-Trisphosphate; Mitogens; Phytohemagglutinins; T-Lymphocytes; Terpenes; Thapsigargin; Tumor Cells, Cultured | 1993 |
Depletion of InsP3 stores activates a Ca2+ and K+ current by means of a phosphatase and a diffusible messenger.
Topics: Animals; Calcium; Cations, Divalent; Cloning, Molecular; Egtazic Acid; Electrophysiology; Ethers, Cyclic; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Okadaic Acid; Oocytes; Phosphoric Monoester Hydrolases; Potassium; Rats; Receptors, Serotonin; Second Messenger Systems; Serotonin; Xenopus | 1993 |
A GTP-dependent step in the activation mechanism of capacitative calcium influx.
Topics: Aluminum Compounds; Animals; Biological Transport; Calcium; Calcium Channels; Cell Membrane; Egtazic Acid; Fluorides; Guanosine Triphosphate; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Ionomycin; Rats; Tumor Cells, Cultured | 1993 |
A lingering elevation of Cai accompanies inhibition of inositol 1,4,5 trisphosphate-induced Ca release in Limulus ventral photoreceptors.
Topics: Aequorin; Animals; Calcium; Egtazic Acid; Horseshoe Crabs; Injections; Inositol 1,4,5-Trisphosphate; Microelectrodes; Photoreceptor Cells; Time Factors | 1993 |
Technique for in situ measurement of calcium in intracellular inositol 1,4,5-trisphosphate-sensitive stores using the fluorescent indicator mag-fura-2.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Cell Membrane Permeability; Digitonin; Egtazic Acid; Fluorescent Dyes; Gastric Mucosa; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Microscopy, Fluorescence; Rabbits; Subcellular Fractions; Terpenes; Thapsigargin | 1993 |
Oleic acid blocks epidermal growth factor-activated early intracellular signals without altering the ensuing mitogenic response.
Topics: Animals; Calcium; Cell Division; Diglycerides; DNA; Egtazic Acid; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Mice; Mitogens; Oleic Acid; Oleic Acids; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases | 1993 |
Intracellular Ca2+ pools in Jurkat T-lymphocytes.
Topics: Antibodies, Monoclonal; Caffeine; Calcium; Calcium-Transporting ATPases; CD3 Complex; Cell Line; Egtazic Acid; Endoplasmic Reticulum; Inositol 1,4,5-Trisphosphate; Ionomycin; Kinetics; T-Lymphocytes; Terpenes; Thapsigargin | 1993 |
Quantal responses to inositol 1,4,5-trisphosphate are not a consequence of Ca2+ regulation of inositol 1,4,5-trisphosphate receptors.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Liver; Male; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Temperature | 1995 |
Local positive feedback by calcium in the propagation of intracellular calcium waves.
Topics: Animals; Biophysical Phenomena; Biophysics; Buffers; Calcium; Calcium Channels; Chelating Agents; Egtazic Acid; Feedback; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ion Transport; Kinetics; Mice; Microscopy, Fluorescence; Microscopy, Video; Models, Biological; Signal Transduction; Tumor Cells, Cultured | 1995 |
Stimulation of Ca(2+)-dependent membrane currents in Xenopus oocytes by microinjection of pyrimidine nucleotide-glucose conjugates.
Topics: Adenosine Diphosphate Glucose; Animals; Calcium; Cell Membrane; Chelating Agents; Egtazic Acid; Female; Glucose; Glycine; Guanosine Diphosphate Sugars; Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Potentials; Microinjections; Nucleoside Diphosphate Sugars; Oocytes; Sulfides; Thiophenes; Uridine Diphosphate Glucose; Xenopus | 1996 |
The relationship between depletion of intracellular Ca2+ stores and activation of Ca2+ current by muscarinic receptors in neuroblastoma cells.
Topics: Animals; Calcium; Calcium Channels; Carbachol; Chelating Agents; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Ganglia, Sympathetic; Inositol 1,4,5-Trisphosphate; Mice; Muscarinic Agonists; Neuroblastoma; Neurons; Receptors, Muscarinic; Second Messenger Systems; Terpenes; Thapsigargin; Tumor Cells, Cultured | 1995 |
Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cell Line; Chelating Agents; Dogs; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Immunoglobulin A; Inositol 1,4,5-Trisphosphate; Microtubules; Models, Biological; Protein Kinase C; Receptors, Polymeric Immunoglobulin; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Activation of Cl- currents in cultured rat retinal pigment epithelial cells by intracellular applications of inositol-1,4,5-triphosphate: differences between rats with retinal dystrophy (RCS) and normal rats.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Chelating Agents; Chloride Channels; Chlorides; Egtazic Acid; Electric Stimulation; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Microinjections; Patch-Clamp Techniques; Pigment Epithelium of Eye; Rats; Rats, Mutant Strains; Retinal Degeneration; Second Messenger Systems | 1996 |
Identification and molecular characterization of a m5 muscarinic receptor in A2058 human melanoma cells. Coupling to inhibition of adenylyl cyclase and stimulation of phospholipase A2.
Topics: Adenylyl Cyclase Inhibitors; Arachidonic Acid; Base Sequence; Blotting, Southern; Calcium; Carbachol; Cell Adhesion; Cell Division; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; DNA Primers; Egtazic Acid; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Melanoma; Molecular Sequence Data; N-Methylscopolamine; Phospholipases A; Phospholipases A2; Polymerase Chain Reaction; Receptor, Muscarinic M5; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction; Time Factors; Tumor Cells, Cultured | 1996 |
Reversible desensitization of inositol trisphosphate-induced calcium release provides a mechanism for repetitive calcium spikes.
Topics: Animals; Calcium; Cell Line; Egtazic Acid; Homeostasis; Inositol 1,4,5-Trisphosphate; Kinetics; Leukemia, Basophilic, Acute; Models, Biological; Oscillometry; Rats; Time Factors; Tumor Cells, Cultured; Type C Phospholipases; Ultraviolet Rays | 1996 |
Arachidonic acid activates the noncapacitative entry of Ca2+ during [Ca2+]i oscillations.
Topics: Alkaloids; Animals; Arachidonic Acid; Benzylisoquinolines; Calcium; Calcium Channel Blockers; Carbachol; Ducks; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Phospholipases A; Phospholipases A2; Proteins; Receptors, Muscarinic; Type C Phospholipases | 1996 |
Transient release of calcium from inositol 1,4,5-trisphosphate-specific stores regulates mouse preimplantation development.
Topics: Animals; Calcimycin; Calcium; Calcium Channels; Calmodulin; Cell Count; Chelating Agents; Culture Techniques; Egtazic Acid; Embryonic and Fetal Development; Embryonic Development; Female; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ionomycin; Mice; Pregnancy; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Sulfonamides | 1996 |
The antidiabetic drug metformin elevates receptor tyrosine kinase activity and inositol 1,4,5-trisphosphate mass in Xenopus oocytes.
Topics: Animals; Cell Division; Chelating Agents; Diglycerides; Egtazic Acid; Enzyme Activation; Female; Heparin; Hypoglycemic Agents; Inositol 1,4,5-Trisphosphate; Insulin; Meiosis; Metformin; Models, Biological; Oocytes; Phosphatidylcholines; Phospholipase D; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptor, Insulin; Type C Phospholipases; Xenopus laevis | 1996 |
Detection of a trigger zone of bradykinin-induced fast calcium waves in PC12 neurites.
Topics: Aniline Compounds; Animals; Benzofurans; Bradykinin; Caffeine; Calcium; Cell Line; Egtazic Acid; Evoked Potentials; Imidazoles; Inositol 1,4,5-Trisphosphate; Microscopy, Confocal; Nerve Growth Factors; Neurites; Neurons; PC12 Cells; Rats; Ryanodine; Xanthenes | 1996 |
Effects of high-density lipoproteins on intracellular pH and proliferation of human vascular endothelial cells.
Topics: Amiloride; Arteriosclerosis; Calcium; Cell Division; Cells, Cultured; Egtazic Acid; Endothelium, Vascular; Epoprostenol; Humans; Hydrogen; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Lipoproteins, HDL; Sodium; Sodium-Hydrogen Exchangers; Umbilical Veins | 1996 |
Conformational states of the nuclear pore complex induced by depletion of nuclear Ca2+ stores.
Topics: Animals; Calcium; Cell Nucleus; Chelating Agents; Diffusion; Egtazic Acid; Female; Inositol 1,4,5-Trisphosphate; Microscopy, Atomic Force; Microscopy, Electron; Nuclear Envelope; Oocytes; Xenopus laevis | 1996 |
Progesterone triggers rapid transmembrane calcium influx and/or calcium mobilization from endoplasmic reticulum, via a pertussis-insensitive G-protein in granulosa cells in relation to luteinization process.
Topics: Animals; Biological Transport; Calcium; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Female; Granulosa Cells; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Luteal Cells; Mifepristone; Pertussis Toxin; Progesterone; Protein Kinase C; Serum Albumin, Bovine; Swine; Thapsigargin; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Phosphoinositide signalling in human neuroblastoma cells: biphasic effect of Li+ on the level of the inositolphosphate second messengers.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Atropine; Calcium; Egtazic Acid; Enzyme Inhibitors; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Maleimides; Neuroblastoma; Nickel; Phosphatidylinositols; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Tumor Cells, Cultured | 1996 |
SR Ca2+ pump heterogeneity in coronary artery: free radicals and IP3-sensitive and -insensitive pools.
Topics: Animals; Azides; Calcimycin; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Coronary Vessels; Egtazic Acid; Free Radicals; Inositol 1,4,5-Trisphosphate; Kinetics; Muscle, Smooth, Vascular; Peroxides; Sarcoplasmic Reticulum; Sodium Azide; Superoxides; Swine; Temperature | 1996 |
Evidence for a Ca2+ pool associated with secretory granules in rat submandibular acinar cells.
Topics: Acetylcholine; Animals; Calcium; Cell Membrane Permeability; Cytoplasmic Granules; Egtazic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoproterenol; Kinetics; Male; Monensin; Rats; Rats, Sprague-Dawley; Sodium; Submandibular Gland; Thapsigargin; Time Factors | 1996 |
Local Ca2+ release from internal stores controls exocytosis in pituitary gonadotrophs.
Topics: Acetates; Animals; Calcium; Chelating Agents; Cytoplasmic Granules; Cytosol; Egtazic Acid; Ethylenediamines; Exocytosis; Gonadotropin-Releasing Hormone; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Photolysis; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Rapid coupling of calcium release to depolarization in Limulus polyphemus ventral photoreceptors as revealed by microphotolysis and confocal microscopy.
Topics: Action Potentials; Adenosine Triphosphate; Aniline Compounds; Animals; Calcium; Drosophila melanogaster; Egtazic Acid; Fluorescent Dyes; Guanosine Diphosphate; Horseshoe Crabs; Inositol 1,4,5-Trisphosphate; Microchemistry; Microscopy, Confocal; Optic Nerve; Organic Chemicals; Patch-Clamp Techniques; Photolysis; Photoreceptor Cells, Invertebrate; Second Messenger Systems; Species Specificity; Thionucleotides; Xanthenes | 1997 |
Ca2+ differentially regulates the ligand-affinity states of type 1 and type 3 inositol 1,4,5-trisphosphate receptors.
Topics: Calcium; Calcium Channels; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ligands; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins | 1997 |
Plasma albumin induces calcium waves in rat cortical astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Egtazic Acid; Gap Junctions; Halothane; Inositol 1,4,5-Trisphosphate; Kinetics; Rats; Ryanodine; Serum Albumin, Bovine; Time Factors | 1997 |
Cyanide-stimulated inositol 1,4,5-trisphosphate formation: an intracellular neurotoxic signaling cascade.
Topics: Animals; Calcium; Cytosol; Egtazic Acid; Inositol 1,4,5-Trisphosphate; PC12 Cells; Poisons; Potassium Cyanide; Rats; Signal Transduction; Type C Phospholipases | 1996 |
Role of intracellular calcium in the angiotensin II-mediated tyrosine phosphorylation and dephosphorylation of PLC-gamma 1.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ionomycin; Isoenzymes; Muscle, Smooth, Vascular; Phospholipase C gamma; Phosphorylation; Rats; Type C Phospholipases; Tyrosine | 1997 |
Domains of high Ca2+ beneath the plasma membrane of living A7r5 cells.
Topics: Aequorin; Animals; Aorta; Calcium; Cell Line; Cell Membrane; Cytosol; DNA Primers; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Proteins; Muscle, Smooth, Vascular; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Processing, Post-Translational; Rats; Recombinant Fusion Proteins; Synaptosomal-Associated Protein 25; Transfection; Vasopressins | 1997 |
Ionophore-releasable lumenal Ca2+ stores are not required for nuclear envelope assembly or nuclear protein import in Xenopus egg extracts.
Topics: Animals; Biological Transport; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Extracts; Chelating Agents; DNA; Egtazic Acid; Enzyme Inhibitors; Indoles; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Nuclear Envelope; Nuclear Proteins; Nucleoplasmins; Ovum; Phosphoproteins; Thapsigargin; Xenopus laevis | 1997 |
Protein kinase C modulator effects on parathyroid hormone-induced intracellular calcium and morphologic changes in UMR 106-H5 osteoblastic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Calcium; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate; Naphthalenes; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Tumor Cells, Cultured | 1997 |
T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis.
Topics: Apoptosis; Calcium; Calcium Channels; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; fas Receptor; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Jurkat Cells; Receptors, Antigen, T-Cell; Receptors, Cytoplasmic and Nuclear; Signal Transduction; T-Lymphocytes; Thapsigargin | 1997 |
Tyrosine phosphorylation-dependent activation of phosphatidylinositide 3-kinase occurs upstream of Ca2+-signalling induced by Fcgamma receptor cross-linking in human neutrophils.
Topics: Androstadienes; Calcium; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Inositol 1,4,5-Trisphosphate; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Receptors, IgG; Signal Transduction; Tyrosine; Wortmannin | 1997 |
Elementary calcium-release units induced by inositol trisphosphate.
Topics: Animals; Calcium; Calcium Channels; Cytosol; Egtazic Acid; Electroporation; Fluorescent Dyes; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Kinetics; Microscopy, Confocal; Microscopy, Fluorescence; Organic Chemicals; Peptides; Rats; Signal Transduction; Tumor Cells, Cultured | 1997 |
Cyclic ADP-ribose-gated Ca2+ release in sea urchin eggs requires an elevated.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium; Chelating Agents; Cyclic ADP-Ribose; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Kinetics; Ovum; Photolysis; Sea Urchins | 1997 |
Stimulation of intracellular Ca2+ levels in human neutrophils by soluble immune complexes. Functional activation of FcgammaRIIIb during priming.
Topics: Animals; Antigen-Antibody Complex; Calcium; Cells, Cultured; Egtazic Acid; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroquinones; Immunoglobulin G; Inositol 1,4,5-Trisphosphate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Protein-Tyrosine Kinases; Rabbits; Reactive Oxygen Species; Receptors, IgG; Serum Albumin; Tumor Necrosis Factor-alpha | 1997 |
Membrane potential and cytosolic free calcium levels modulate acetylcholine-induced inositol phosphate production in insulin-secreting BTC3 cells.
Topics: Acetylcholine; Animals; Calcium; Cell Line; Cytosol; Egtazic Acid; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Insulin; Ionomycin; Membrane Potentials; Mice; Receptors, Muscarinic; Time Factors; Type C Phospholipases | 1996 |
A volume-sensitive, IP3-insensitive Ca2+ store in vascular endothelial cells.
Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Cattle; Cell Membrane Permeability; Cells, Cultured; Culture Media; Egtazic Acid; Endothelium, Vascular; Fluorescent Dyes; Fura-2; Gadolinium; Hypotonic Solutions; Inositol 1,4,5-Trisphosphate; Kinetics; Lanthanum; Membrane Potentials; Ruthenium Red | 1997 |
Calcium release from intracellular stores evoked by extracellular ATP in a Xenopus renal epithelial cell line.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line; Egtazic Acid; Epithelium; Fura-2; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Kidney; Kinetics; Membrane Potentials; Microscopy, Fluorescence; Neomycin; Patch-Clamp Techniques; Pertussis Toxin; Signal Transduction; Thionucleotides; Virulence Factors, Bordetella; Xenopus | 1997 |
Desensitization of thyrotropin-releasing hormone receptor-mediated responses involves multiple steps.
Topics: Calcium; Cell Line; Chelating Agents; Egtazic Acid; Fluorescent Dyes; Fura-2; Humans; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Kinetics; Receptors, Thyrotropin-Releasing Hormone; Thyrotropin-Releasing Hormone | 1997 |
Endothelin-B receptor-mediated Ca2+ signaling in human melanocytes.
Topics: Calcium; Calcium-Transporting ATPases; Cells, Cultured; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Enzyme Activation; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Male; Melanocytes; Peptide Fragments; Peptides, Cyclic; Pyrrolidinones; Receptor, Endothelin B; Receptors, Endothelin; Signal Transduction; Thapsigargin; Type C Phospholipases | 1998 |
Erythrocyte lysate releases Ca2+ from IP3-sensitive stores and activates Ca(2+)-dependent K+ channels in rat basilar smooth muscle cells.
Topics: Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Cell Extracts; Chelating Agents; Dogs; Egtazic Acid; Erythrocytes; Female; Image Processing, Computer-Assisted; Inositol 1,4,5-Trisphosphate; Muscle, Smooth, Vascular; Nicardipine; Patch-Clamp Techniques; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1998 |
Ca2+-dependent K+ currents induced by muscarinic receptor activation in guinea pig adrenal chromaffin cells.
Topics: Animals; Apamin; Calcium; Charybdotoxin; Chelating Agents; Chromaffin Cells; Egtazic Acid; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Muscarine; Muscarinic Agonists; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Receptors, Muscarinic; Second Messenger Systems | 1998 |
Allosteric regulation by cytoplasmic Ca2+ and IP3 of the gating of IP3 receptors in permeabilized guinea-pig vascular smooth muscle cells.
Topics: Action Potentials; Allosteric Regulation; Allosteric Site; Animals; Calcium; Calcium Channels; Cell Membrane Permeability; Chelating Agents; Cytoplasm; Dose-Response Relationship, Drug; Egtazic Acid; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Muscle, Smooth, Vascular; Receptors, Cytoplasmic and Nuclear; Sensitivity and Specificity | 1998 |
Activation of inositol 1,4,5-trisphosphate receptors induces transient changes in cell shape of fertilized Xenopus eggs.
Topics: Actin Cytoskeleton; Adenosine; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Cell Size; Chelating Agents; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Microinjections; Receptors, Cytoplasmic and Nuclear; Xenopus laevis; Zygote | 1998 |
Roles of Ca2+, inositol trisphosphate and cyclic ADP-ribose in mediating intercellular Ca2+ signaling in sheep lens cells.
Topics: Animals; Calcium; Cell Communication; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Gap Junctions; Inositol 1,4,5-Trisphosphate; Ion Transport; Lens, Crystalline; Microinjections; Microscopy, Fluorescence; Phosphatidylinositol Diacylglycerol-Lyase; Poly Adenosine Diphosphate Ribose; Pyrrolidinones; Sheep; Signal Transduction; Type C Phospholipases | 1998 |
Kinetic basis of quantal calcium release from intracellular calcium stores.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Cerebellum; Chelating Agents; Dogs; Dopamine Antagonists; Egtazic Acid; Energy Metabolism; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Kinetics; Microsomes; Muscle, Skeletal; Phosphodiesterase Inhibitors; Rabbits; Radioligand Assay; Trifluoperazine; Tritium | 1998 |
Slow feedback inhibition of calcium release-activated calcium current by calcium entry.
Topics: Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Feedback; Inositol 1,4,5-Trisphosphate; Ion Channels; Ionomycin; Patch-Clamp Techniques; Rats; Signal Transduction; Thapsigargin; Tumor Cells, Cultured | 1998 |
Delayed activation of the store-operated calcium current induced by calreticulin overexpression in RBL-1 cells.
Topics: Animals; Calcium; Calcium Channels; Calcium-Binding Proteins; Calreticulin; Chelating Agents; Egtazic Acid; Electrophysiology; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Rats; Recombinant Fusion Proteins; Ribonucleoproteins; Tumor Cells, Cultured | 1998 |
Rise of intracellular free calcium levels with activation of inositol triphosphate in a human colonic carcinoma cell line (COLO 205) by heat-stable enterotoxin of Escherichia coli.
Topics: Bacterial Toxins; Calcium; Colonic Neoplasms; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Enterotoxins; Escherichia coli Proteins; Extracellular Space; Fluorescent Dyes; Fura-2; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Time Factors; Tritium; Tumor Cells, Cultured | 1998 |
Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes.
Topics: Animals; Antisense Elements (Genetics); Calcium; Chelating Agents; Chlorides; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Estrenes; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Inositol 1,4,5-Trisphosphate; Isoenzymes; Lysophospholipids; Niflumic Acid; Oligonucleotide Probes; Oocytes; Patch-Clamp Techniques; Periodicity; Phospholipase C beta; Pyrrolidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; RNA, Messenger; Signal Transduction; Sphingosine; Thapsigargin; Type C Phospholipases; Xenopus laevis | 1998 |
Non-specific currents at fertilisation in sea urchin oocytes.
Topics: Animals; Calcium; Dithiothreitol; Egtazic Acid; Exocytosis; Female; Fertilization; Inositol 1,4,5-Trisphosphate; Ion Transport; Male; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Sea Urchins; Sperm-Ovum Interactions; Zygote | 1998 |
Regulation of KCa current by store-operated Ca2+ influx depends on internal Ca2+ release in HSG cells.
Topics: Atropine; Calcium; Carbachol; Cations; Cells, Cultured; Chelating Agents; Egtazic Acid; Gadolinium; Humans; Inositol 1,4,5-Trisphosphate; Lanthanum; Membrane Potentials; Models, Biological; Patch-Clamp Techniques; Potassium Channels; Submandibular Gland; Thapsigargin; Zinc | 1998 |
Modulation of secretin release by neuropeptides in secretin-producing cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bombesin; Cell Line; Cell Survival; Cells, Cultured; Cyclic AMP; Diltiazem; Egtazic Acid; Galanin; Gastrin-Releasing Peptide; Inositol 1,4,5-Trisphosphate; Intestinal Mucosa; Intestine, Small; Male; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Secretin; Tetradecanoylphorbol Acetate; Thionucleotides | 1998 |
Signal transduction pathways mediating CCK-induced gallbladder muscle contraction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzimidazoles; Calcium; Calmodulin; Cats; Cell Membrane; Cholecystokinin; Diglycerides; Egtazic Acid; Female; Gallbladder; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoenzymes; Male; Muscle Contraction; Muscle, Smooth; Pertussis Toxin; Phospholipase C beta; Potassium Chloride; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella | 1998 |
ADP and inositol trisphosphate evoke oscillations of a monovalent cation conductance in rat megakaryocytes.
Topics: Adenosine Diphosphate; Animals; Calcium Signaling; Cations; Cesium; Charybdotoxin; Chelating Agents; Chlorides; Egtazic Acid; Fluorescent Dyes; Fura-2; Gluconates; Inositol 1,4,5-Trisphosphate; Male; Megakaryocytes; Meglumine; Patch-Clamp Techniques; Periodicity; Potassium Channels; Rats; Rats, Wistar; Sodium Chloride | 1998 |
Calcium released from intracellular stores inhibits GABAA-mediated currents in ganglion cells of the turtle retina.
Topics: Alkaline Phosphatase; Animals; Bicuculline; Caffeine; Calcineurin; Calcium; Calcium Channels; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Membrane Potentials; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Pyridazines; Receptors, Cytoplasmic and Nuclear; Receptors, GABA-A; Retinal Ganglion Cells; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin; Turtles | 1998 |
Comparison of the effects of hydrogen peroxide, 4-hydroxy-2-nonenal and beta-amyloid (25-35) upon calcium signalling.
Topics: Aldehydes; Amyloid beta-Peptides; Animals; Blood Platelets; Calcium; Calcium Channels; Cerebral Cortex; Chelating Agents; Dithiothreitol; Egtazic Acid; Humans; Hydrogen Peroxide; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Peptide Fragments; Phosphatidylinositols; Rats; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thrombin | 1998 |
In vivo signal transduction of tetrodotoxin-sensitive nociceptive responses by substance P given into the planta of the mouse hind limb.
Topics: Action Potentials; Afferent Pathways; Animals; Biphenyl Compounds; Calcium Signaling; Egtazic Acid; Estrenes; GTP-Binding Proteins; Hindlimb; Inositol 1,4,5-Trisphosphate; Ion Transport; Male; Mice; Mice, Inbred Strains; Models, Neurological; Muscle Contraction; Neurons, Afferent; Neurotoxins; Nociceptors; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Neurokinin-1; Reflex; Signal Transduction; Substance P; Tetrodotoxin; Type C Phospholipases | 1998 |
Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools.
Topics: 3T3 Cells; Animals; Blood Proteins; Calcium; Cell Membrane; Chelating Agents; COS Cells; Egtazic Acid; Green Fluorescent Proteins; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Luminescent Proteins; Mice; Phosphatidylinositol 4,5-Diphosphate; Phosphoproteins; Protein Binding; Protein Structure, Tertiary; Transfection; Tritium; Type C Phospholipases | 1998 |
Ca2+-dependent capacitance increases in rat basophilic leukemia cells following activation of store-operated Ca2+ entry and dialysis with high-Ca2+-containing intracellular solution.
Topics: Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Chelating Agents; Dialysis; Egtazic Acid; Electric Conductivity; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Leukemia, Basophilic, Acute; Rats; Thapsigargin; Tumor Cells, Cultured | 1998 |
Effect of adenophostin A on Ca2+ entry and calcium release-activated calcium current (Icrac) in rat basophilic leukemia cells.
Topics: Adenosine; Animals; Barium; Calcium; Calcium Channels; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Leukemia, Basophilic, Acute; Rats; Time Factors; Tumor Cells, Cultured | 1998 |
Activation of heterologously expressed Drosophila TRPL channels: Ca2+ is not required and InsP3 is not sufficient.
Topics: Animals; Calcium; Calcium Signaling; Calmodulin-Binding Proteins; Carbachol; Chelating Agents; Drosophila; Drosophila Proteins; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Membrane Proteins; Recombinant Proteins; Transient Receptor Potential Channels; Type C Phospholipases | 1998 |
Calcium/calmodulin-dependent signaling for appressorium formation in the plant pathogenic fungus Magnaporthe grisea.
Topics: Adrenergic alpha-Antagonists; Ascomycota; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Calmodulin; Chelating Agents; Chlorpromazine; Dopamine Antagonists; Egtazic Acid; Gallic Acid; Gallopamil; Inositol 1,4,5-Trisphosphate; Ionophores; Neomycin; Oryza; Phenoxybenzamine; Protein Synthesis Inhibitors; Sesterterpenes; Signal Transduction; Spores, Fungal; Sulfonamides; Terpenes; Type C Phospholipases | 1998 |
Single-channel recording of a store-operated Ca2+ channel in Jurkat T lymphocytes.
Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Egtazic Acid; Electric Conductivity; Gadolinium; Humans; Inositol 1,4,5-Trisphosphate; Jurkat Cells; Magnesium; Membrane Potentials; Nickel; Patch-Clamp Techniques; Sodium; T-Lymphocytes | 1999 |
Induction of Na+ channel voltage sensitivity in Xenopus oocytes depends on Ca2+ mobilization.
Topics: Animals; Caffeine; Calcium; Chelating Agents; Egtazic Acid; Female; Heparin; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Membrane Potentials; Oocytes; Sodium Channels; Xenopus laevis | 1999 |
Fast calcium-dependent inactivation of calcium release-activated calcium current (CRAC) in RBL-1 cells.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cations, Divalent; Chelating Agents; Cysteine; Egtazic Acid; Glutathione; Inositol 1,4,5-Trisphosphate; Kinetics; Leukemia, Basophilic, Acute; Membrane Potentials; Oxidation-Reduction; Rats; Receptors, IgE; Signal Transduction; Time Factors; Tumor Cells, Cultured | 1999 |
Lipoprotein(a) stimulates growth of human mesangial cells and induces activation of phospholipase C via pertussis toxin-sensitive G proteins.
Topics: Blood Proteins; Calcium; Cell Division; DNA; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Estrenes; Glomerular Mesangium; GTP-Binding Proteins; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Lipoprotein(a); Pertussis Toxin; Phosphodiesterase Inhibitors; Pyrrolidinones; Type C Phospholipases; Vasopressins; Virulence Factors, Bordetella | 1999 |
Functional uncoupling between intracellular calcium dynamics and secretion in the alphaT3-1 gonadotropic cell line.
Topics: Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line; Cell Survival; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Exocytosis; Fluorescent Dyes; Gadolinium; Glycoprotein Hormones, alpha Subunit; Glycoproteins; Gonadotropin-Releasing Hormone; Indoles; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; L-Lactate Dehydrogenase; Membrane Potentials; Nifedipine; Pituitary Gland; Receptors, LHRH; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sulfur Radioisotopes; Thapsigargin; Tritium | 1999 |
The bell-shaped Ca2+ dependence of the inositol 1,4, 5-trisphosphate-induced Ca2+ release is modulated by Ca2+/calmodulin.
Topics: Animals; Aorta; Brain Chemistry; Calcium; Calcium Channels; Calmodulin; Cattle; Cell Line; Chelating Agents; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Rats; Receptors, Cytoplasmic and Nuclear; Strontium | 1999 |
Conformational changes of the in situ nuclear pore complex.
Topics: Adenosine Triphosphate; Animals; Calcium; Diffusion; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Microscopy, Atomic Force; Nuclear Envelope; Nuclear Proteins; Oocytes; Protein Conformation; Xenopus | 1999 |
Expression of Ca(2+)-mobilizing endothelin(A) receptors and their role in the control of Ca(2+) influx and growth hormone secretion in pituitary somatotrophs.
Topics: Adenylate Cyclase Toxin; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Egtazic Acid; Endothelin-1; Female; Growth Hormone; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Pertussis Toxin; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Somatostatin; Virulence Factors, Bordetella | 1999 |
The role of Ca2+ feedback in shaping InsP3-evoked Ca2+ signals in mouse pancreatic acinar cells.
Topics: Acetates; Animals; Buffers; Calcium; Calcium Signaling; Chelating Agents; Egtazic Acid; Electric Stimulation; Electrophysiology; Ethylenediamines; Feedback; Fluorescent Dyes; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Mice; Pancreas; Patch-Clamp Techniques; Photolysis | 1999 |
Maitotoxin-induced phosphoinositide hydrolysis is dependent on extracellular but not intracellular Ca2+ in human astrocytoma cells.
Topics: Astrocytoma; Brain Neoplasms; Calcimycin; Calcium; Chelating Agents; Egtazic Acid; Extracellular Space; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate; Ionophores; Marine Toxins; Oxocins; Phosphatidylinositols; Tumor Cells, Cultured | 1999 |
Internal calcium modulates apparent affinity of metabotropic GABA receptors.
Topics: Ambystoma; Animals; Baclofen; Calcium Signaling; Cell Polarity; Chelating Agents; Egtazic Acid; Electric Stimulation; Electrophysiology; Feedback; Fluorescent Dyes; GABA Antagonists; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Retinal Ganglion Cells | 1999 |
alpha(2A)-adrenergic receptor stimulation potentiates calcium release in platelets by modulating cAMP levels.
Topics: Adrenergic alpha-Agonists; Aspirin; Blood Platelets; Brimonidine Tartrate; Calcium; Calcium Chloride; Carbazoles; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Epinephrine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Models, Biological; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Prostaglandins E; Pyrroles; Quinoxalines; Receptors, Adrenergic, alpha-2; Stimulation, Chemical; Thapsigargin; Thimerosal; Thrombin; Time Factors | 2000 |
Cdc42 and Rac stimulate exocytosis of secretory granules by activating the IP(3)/calcium pathway in RBL-2H3 mast cells.
Topics: Animals; Calcium Channels; Calcium Signaling; cdc42 GTP-Binding Protein; Cell Degranulation; Cell Line; Chlorocebus aethiops; Cytoplasmic Granules; Dinitrophenols; Egtazic Acid; Enzyme Activation; Exocytosis; Gene Expression; Genetic Vectors; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoenzymes; Mast Cells; Mutagenesis; Phospholipase C gamma; Protein Kinase C; rac GTP-Binding Proteins; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Serum Albumin, Bovine; Type C Phospholipases; Vaccinia virus | 2000 |
Calcium, ATP and nuclear pore channel gating.
Topics: Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Biological Transport; Calcium; Calcium Channels; Chelating Agents; Cytosol; Dextrans; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Male; Nuclear Envelope; Oocytes; Patch-Clamp Techniques; Prostatic Neoplasms; Thapsigargin; Tumor Cells, Cultured; Xenopus laevis | 2000 |
Ca2+ store dynamics determines the pattern of activation of the store-operated Ca2+ current I(CRAC) in response to InsP3 in rat basophilic leukaemia cells.
Topics: Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Chelating Agents; Dialysis; Disulfiram; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Inositol Polyphosphate 5-Phosphatases; Intracellular Fluid; Ion Transport; Leukemia, Basophilic, Acute; Membrane Potentials; Patch-Clamp Techniques; Phosphoric Monoester Hydrolases; Rats; Signal Transduction; Substrate Specificity; Tumor Cells, Cultured | 2000 |
Two Ca2+ entry pathways mediate InsP3-sensitive store refilling in guinea-pig colonic smooth muscle.
Topics: Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Colon; Egtazic Acid; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Male; Membrane Potentials; Muscle, Smooth; Nimodipine; Sarcolemma; Xanthenes | 2000 |
The carcinogen Cd(2+) activates InsP(3)-mediated Ca(2+) release through a specific metal ion receptor in Xenopus oocyte.
Topics: Animals; Anthracenes; Cadmium; Caffeine; Calcium Signaling; Carrier Proteins; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Ethylmaleimide; Female; Heparin; Inositol 1,4,5-Trisphosphate; Ion Transport; Lysophospholipids; Membrane Potentials; Membrane Proteins; Mercaptoethanol; Microinjections; Neomycin; Oocytes; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Thapsigargin; Type C Phospholipases; Xenopus laevis | 2000 |
Inositol hexakisphosphate is a physiological signal regulating the K+-inward rectifying conductance in guard cells.
Topics: Chelating Agents; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Phytic Acid; Plant Proteins; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protoplasts; Solanum tuberosum; Stereoisomerism | 2000 |
Phasic characteristic of elementary Ca(2+) release sites underlies quantal responses to IP(3).
Topics: Animals; Buffers; Calcium; Calcium Signaling; Chelating Agents; Egtazic Acid; Image Processing, Computer-Assisted; Inositol 1,4,5-Trisphosphate; Kinetics; Microinjections; Microscopy, Confocal; Models, Biological; Oocytes; Photolysis; Ultraviolet Rays; Xenopus laevis | 2000 |
Effects of bradykinin on prostaglandin I(2) synthesis in human vascular endothelial cells.
Topics: Bradykinin; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Epoprostenol; Gene Expression Regulation, Enzymologic; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Phospholipases A; Prostaglandin-Endoperoxide Synthases; RNA, Messenger | 2000 |
Calcium signalling in sarcoplasmic reticulum, cytoplasm and mitochondria during activation of rabbit aorta myocytes.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Calcium Signaling; Cells, Cultured; Cytoplasm; Dialysis; Egtazic Acid; Fluorescence; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Male; Mitochondria, Muscle; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Saponins; Sarcoplasmic Reticulum | 2000 |
Inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release evoked by metabotropic agonists and backpropagating action potentials in hippocampal CA1 pyramidal neurons.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Chelating Agents; Cycloleucine; Dendrites; Dose-Response Relationship, Drug; Egtazic Acid; Fluorescent Dyes; Hippocampus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Metabotropic Glutamate | 2000 |
Activation of calcium entry in human carcinoma A431 cells by store depletion and phospholipase C- dependent mechanisms converge on ICRAC-like calcium channels.
Topics: Calcium; Calcium Channels; Carcinoma; Cell Membrane; Egtazic Acid; Electric Conductivity; Humans; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Models, Biological; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases; Uridine Triphosphate | 2001 |
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice.
Topics: Acetylcholine; Animals; Calcium; Calcium Channels; Cation Transport Proteins; Chelating Agents; Egtazic Acid; Electrophysiology; Endothelium, Vascular; Enzyme Inhibitors; Female; Gene Targeting; Hydroquinones; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lanthanum; Male; Mice; Patch-Clamp Techniques; TRPC Cation Channels; Vasodilation | 2001 |
Intercellular calcium signaling and flash photolysis of caged compounds. A sensitive method to evaluate gap junctional coupling.
Topics: Adenosine Diphosphate Ribose; Animals; Astrocytes; Calcium Signaling; Cell Communication; Cells, Cultured; Cyclic ADP-Ribose; Egtazic Acid; Electroporation; Endothelium, Vascular; Gap Junctions; Inositol 1,4,5-Trisphosphate; Microinjections; Photolysis; Rats; Sensitivity and Specificity | 2001 |
Energized mitochondria increase the dynamic range over which inositol 1,4,5-trisphosphate activates store-operated calcium influx.
Topics: Animals; Calcium; Calcium Channels; Egtazic Acid; Humans; Inositol 1,4,5-Trisphosphate; Jurkat Cells; Kinetics; Leukemia, Basophilic, Acute; Mitochondria; Models, Biological; Rats; Tumor Cells, Cultured | 2001 |
Control of IP(3)-mediated Ca2+ puffs in Xenopus laevis oocytes by the Ca2+-binding protein parvalbumin.
Topics: Animals; Buffers; Calbindins; Calcium; Carboxylic Acids; Chelating Agents; Coloring Agents; Cytosol; Egtazic Acid; Female; Heparin; Inositol 1,4,5-Trisphosphate; Oocytes; Parvalbumins; Reaction Time; S100 Calcium Binding Protein G; Xenopus laevis | 2001 |
Stimulation by thimerosal of histamine-induced Ca(2+) release in intact HeLa cells seen with aequorin targeted to the endoplasmic reticulum.
Topics: Aequorin; Calcium; Calcium Signaling; Dithiothreitol; Drug Synergism; Egtazic Acid; Endoplasmic Reticulum; Glutathione; HeLa Cells; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Manganese; Oxidation-Reduction; Protein Transport; Thimerosal | 2001 |
Regulation of eosinophil function by phosphatidylinositol-specific PLC and cytosolic PLA(2).
Topics: Arachidonic Acid; Biomarkers; Calcium; Chelating Agents; Cytosol; Egtazic Acid; Eosinophil Peroxidase; Eosinophils; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Ketones; Leukotriene C4; Peroxidases; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phosphoinositide Phospholipase C; Phospholipase C beta; Phospholipase C gamma; Phospholipases A; Phospholipid Ethers; Protein Kinase C; Type C Phospholipases; Virulence Factors, Bordetella | 2001 |
Dense core secretory vesicles revealed as a dynamic Ca(2+) store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera.
Topics: Adenosine Triphosphate; Adenoviridae; Aequorin; Animals; Caffeine; Calcium; Cell Line; Central Nervous System Stimulants; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Genes, Reporter; Imidazoles; Immunohistochemistry; Inositol 1,4,5-Trisphosphate; Islets of Langerhans; Membrane Proteins; Nerve Tissue Proteins; Pyrazines; R-SNARE Proteins; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel; Secretory Vesicles | 2001 |
Production of beta-defensin-2 by human colonic epithelial cells induced by Salmonella enteritidis flagella filament structural protein.
Topics: beta-Defensins; Caco-2 Cells; Calcium; Cell Nucleus; Chelating Agents; Colon; Culture Media; Egtazic Acid; Estrenes; Flagellin; Heparin; Humans; Inositol 1,4,5-Trisphosphate; Intestinal Mucosa; NF-kappa B; Pertussis Toxin; Promoter Regions, Genetic; Pyrrolidinones; RNA, Messenger; Salmonella enteritidis; Signal Transduction; Up-Regulation; Virulence Factors, Bordetella | 2001 |
Histamine-induced Ca2+ release in bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Caffeine; Calcium; Cattle; Cells, Cultured; Chromaffin Cells; Egtazic Acid; Electric Stimulation; Extracellular Space; Histamine; Histamine Agonists; Histamine Antagonists; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Mitochondria; Thapsigargin | 2001 |
myo-Inositol 1,4,5-trisphosphate and Ca(2+)/calmodulin-dependent factors mediate transduction of compression-induced signals in bovine articular chondrocytes.
Topics: Aggrecans; Alkaloids; Animals; Benzophenanthridines; Benzylamines; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cartilage; Cattle; Chondrocytes; Cyclic AMP; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix Proteins; Indoles; Inositol 1,4,5-Trisphosphate; Lectins, C-Type; Maleimides; Models, Biological; Phenanthridines; Protein Kinase C; Proteoglycans; RNA, Messenger; Signal Transduction; Sulfonamides; Thapsigargin; Time Factors | 2002 |
The recombinant human TRPV6 channel functions as Ca2+ sensor in human embryonic kidney and rat basophilic leukemia cells.
Topics: Animals; Blotting, Northern; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cations; Cell Line; Chelating Agents; Cytosol; DNA, Complementary; Egtazic Acid; Electrophysiology; Humans; Inositol 1,4,5-Trisphosphate; Leukemia; Rats; Recombinant Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Time Factors; Transfection; TRPV Cation Channels; Tumor Cells, Cultured | 2002 |
Magnesium sulfate inhibits the oxytocin-induced production of inositol 1,4,5-trisphosphate in cultured human myometrial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Culture Techniques; Cells, Cultured; Drug Interactions; Egtazic Acid; Female; Humans; Inositol 1,4,5-Trisphosphate; Magnesium Sulfate; Myometrium; Nifedipine; Oxytocin; Sodium Fluoride | 2002 |
The intraacrosomal calcium pool plays a direct role in acrosomal exocytosis.
Topics: Acrosome; Acrosome Reaction; Calcium; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Exocytosis; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Ligands; Light; Male; rab3A GTP-Binding Protein; Recombinant Proteins; Spectrometry, Fluorescence; Spermatozoa; Thapsigargin; Time Factors; Ultraviolet Rays | 2002 |
Vortex-mediated mechanical stress induces integrin-dependent cell adhesion mediated by inositol 1,4,5-trisphosphate-sensitive Ca2+ release in THP-1 cells.
Topics: Calcium; Calmodulin; Cell Adhesion; Cell Line; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Estrenes; Fibronectins; Humans; Inositol 1,4,5-Trisphosphate; Integrin beta1; Integrins; Monocytes; Pyrrolidinones; Stress, Mechanical; Sulfonamides; Time Factors | 2003 |
Fertilization and activation currents in bovine oocytes.
Topics: Animals; Caffeine; Calcium; Cattle; Cell Membrane; Chelating Agents; Egtazic Acid; Ethanol; Female; Fertilization in Vitro; Inositol 1,4,5-Trisphosphate; Ionophores; Oocytes; Oogenesis; Parthenogenesis; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Sperm-Ovum Interactions; Stimulation, Chemical; Thapsigargin | 2002 |
Intracellular calcium release resulting from mGluR1 receptor activation modulates GABAA currents in wide-field retinal amacrine cells: a study with caffeine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amacrine Cells; Animals; Anticoagulants; Bicuculline; Caffeine; Calcium; Calcium Channels; Carps; Cells, Cultured; Central Nervous System Stimulants; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Conductivity; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Space; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heparin; Immunohistochemistry; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kainic Acid; Membrane Potentials; Methoxyhydroxyphenylglycol; Organophosphorus Compounds; Patch-Clamp Techniques; Receptors, Cytoplasmic and Nuclear; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Retina; Ryanodine | 2003 |
Sequential activation of store-operated currents in human gingival keratinocytes.
Topics: Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Gingiva; Humans; Inositol 1,4,5-Trisphosphate; Keratinocytes; Membrane Potentials; Patch-Clamp Techniques; Sodium; Thapsigargin | 2003 |
A reassessment of the effects of luminal [Ca2+] on inositol 1,4,5-trisphosphate-induced Ca2+ release from internal stores.
Topics: Animals; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Cell Line; Chelating Agents; Cricetinae; Egtazic Acid; Enzyme Inhibitors; Ethylenediamines; Hydroquinones; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Metals, Heavy; Receptors, Cytoplasmic and Nuclear; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2003 |
Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
Topics: Animals; Buffers; Calcium; Calcium Channels; Calcium Signaling; Cytosol; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Microscopy, Confocal; Oocytes; Receptors, Cytoplasmic and Nuclear; Xenopus laevis; Xenopus Proteins | 2003 |
Localized IP3-evoked Ca2+ release activates a K+ current in primary vagal sensory neurons.
Topics: Animals; Calcium; Calcium Signaling; Calibration; Chelating Agents; Egtazic Acid; Electrophysiology; Extracellular Space; In Vitro Techniques; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Membrane Potentials; Neurons, Afferent; Patch-Clamp Techniques; Photolysis; Potassium Channels, Calcium-Activated; Rabbits; Vagus Nerve | 2004 |
Small-conductance Ca2+-dependent K+ channels are the target of spike-induced Ca2+ release in a feedback regulation of pyramidal cell excitability.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Carbachol; Chelating Agents; Egtazic Acid; Electrophysiology; Feedback; Image Processing, Computer-Assisted; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Muscarinic Agonists; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Pyramidal Cells; Rats; Rats, Wistar; Visual Cortex | 2004 |
Mechanism of collagen activation in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Benzofurans; Blood Platelets; Calcium; Collagen; Dose-Response Relationship, Drug; Egtazic Acid; Ethers, Cyclic; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Imidazoles; Inositol 1,4,5-Trisphosphate; Models, Biological; Organic Chemicals; Platelet Activation; Platelet Aggregation; Sodium; Sodium-Calcium Exchanger; Specimen Handling; Temperature; Thromboxane A2; Time Factors; Vasoconstrictor Agents | 2004 |
The potential signalling pathways which regulate surface changes induced by phytohormones in the potato cyst nematode (Globodera rostochiensis).
Topics: Adenine; Adenosine Triphosphate; Animals; Calcium; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Indoleacetic Acids; Inositol 1,4,5-Trisphosphate; Kinetin; Microscopy, Fluorescence; Nematoda; Nematode Infections; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Plant Diseases; Signal Transduction; Solanum tuberosum; Surface Properties; Type C Phospholipases | 2004 |
Involvement of inositol 1,4,5-trisphosphate in nicotinic calcium responses in dystrophic myotubes assessed by near-plasma membrane calcium measurement.
Topics: Aequorin; Animals; Calcium; Calcium Channels; Carbachol; Cell Membrane; Cholinergic Agonists; Cytosol; Egtazic Acid; Green Fluorescent Proteins; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Membrane Proteins; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Muscle, Skeletal; Myocardium; Necrosis; Nerve Tissue Proteins; Phosphoproteins; Plasmids; Receptors, Cytoplasmic and Nuclear; Receptors, Nicotinic; Sarcoplasmic Reticulum; Synaptosomal-Associated Protein 25; Time Factors; Transfection | 2004 |
The role of mitochondria for Ca2+ refilling of the endoplasmic reticulum.
Topics: Calcium; Calcium-Transporting ATPases; Cells, Cultured; Clonazepam; Cytoplasm; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Endothelium, Vascular; Histamine; Humans; Image Processing, Computer-Assisted; Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Potentials; Mitochondria; Models, Biological; Plasmids; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thiazepines; Time Factors; Transfection; Umbilical Veins | 2005 |
The role of Ca2+ in triggering inositol 1,4,5-trisphosphate receptor ubiquitination.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cell Line; Down-Regulation; Egtazic Acid; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Hemagglutinins; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Nifedipine; Point Mutation; Protein Binding; Receptors, Cytoplasmic and Nuclear; Thapsigargin; Ubiquitin | 2005 |
Rhythmic expression of adenylyl cyclase VI contributes to the differential regulation of serotonin N-acetyltransferase by bradykinin in rat pineal glands.
Topics: Adenylyl Cyclases; Animals; Arylalkylamine N-Acetyltransferase; Blotting, Northern; Bradykinin; Calcium; Chelating Agents; Circadian Rhythm; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Gene Expression Regulation, Enzymologic; Immunoblotting; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Isoproterenol; Male; Melatonin; Norepinephrine; Pertussis Toxin; Phosphodiesterase Inhibitors; Pineal Gland; Protein Isoforms; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Superior Cervical Ganglion; Time Factors; Transcriptional Activation; Type C Phospholipases | 2005 |
Gap junctions remain open during cytochrome c-induced cell death: relationship of conductance to 'bystander' cell killing.
Topics: Animals; Apoptosis; Calcium Signaling; Cell Communication; Cytochromes c; Egtazic Acid; Electric Conductivity; Female; Gap Junctions; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Oocytes; Oxazoles; Xenopus laevis | 2006 |
Intracellular Ca2+ increase induces post-fertilization events via MAP kinase dephosphorylation in eggs of the hydrozoan jellyfish Cladonema pacificum.
Topics: Animals; Butadienes; Calcium; Cell Adhesion; Cell Cycle; Chelating Agents; Egtazic Acid; Fertilization; Hydrozoa; Inositol 1,4,5-Trisphosphate; Mitogen-Activated Protein Kinases; Nitriles; Ovum; Phosphorylation | 2006 |
Mechanisms underlying type I mGluR-induced activation of lobster gastric mill neurons.
Topics: Animals; Calcium; Chelating Agents; Egtazic Acid; Electrodes; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Neurons; Palinuridae; Quisqualic Acid; Receptors, Metabotropic Glutamate; Second Messenger Systems; Signal Transduction; Stomach; Type C Phospholipases | 2006 |
Cell cycle-dependent calcium oscillations in mouse embryonic stem cells.
Topics: Adenosine Triphosphatases; Animals; Boron Compounds; Calcium; Calcium Signaling; Cell Cycle; Cells, Cultured; Chelating Agents; Egtazic Acid; Embryonic Stem Cells; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Protein Isoforms; Pyrrolidinones; Thapsigargin; Type C Phospholipases | 2007 |
Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice.
Topics: Action Potentials; Animals; Animals, Newborn; Calcium; Calcium Signaling; Chelating Agents; Egtazic Acid; Flufenamic Acid; Glutamic Acid; In Vitro Techniques; Inhalation; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Mice; Mice, Inbred C57BL; Neurons; Periodicity; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Respiratory Center; Synapses; Synaptic Transmission | 2007 |
Role of TRPV1 and intracellular Ca2+ in excitation of cardiac sensory neurons by bradykinin.
Topics: Animals; Arachidonate 12-Lipoxygenase; Bradykinin; Calcium; Chelating Agents; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Extracellular Space; Flavanones; Ganglia, Spinal; Heart; Inositol 1,4,5-Trisphosphate; Intracellular Space; Male; Membrane Potentials; Neurons, Afferent; Nociceptors; Rats; Rats, Sprague-Dawley; Thapsigargin; TRPV Cation Channels | 2007 |
Endoplasmic reticulum is a key organella in bradykinin-triggered ATP release from cultured smooth muscle cells.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Benzyl Compounds; Boron Compounds; Bradykinin; Calcium; Calcium Channel Blockers; Cells, Cultured; Colon; Egtazic Acid; Endoplasmic Reticulum; Estrenes; Ethylmaleimide; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Male; Microscopy, Confocal; Muscle, Smooth; Nifedipine; Pyrrolidinones; Receptor, Bradykinin B2; Rotenone; Thapsigargin; Thiazolidines; Verapamil | 2007 |
Mechanical stress induces tumor necrosis factor-{alpha} production through Ca2+ release-dependent TLR2 signaling.
Topics: Antibodies; Calcium; Calcium Signaling; Cell Line; Cell Line, Tumor; Egtazic Acid; Endotoxins; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Monocytes; Myeloid Differentiation Factor 88; NF-kappa B; Nickel; Phosphorylation; Polymyxin B; Pyrazoles; Pyrimidines; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stress, Mechanical; Thapsigargin; Toll-Like Receptor 2; Transfection; Tumor Necrosis Factor-alpha | 2008 |
Automated patch-clamp technique: increased throughput in functional characterization and in pharmacological screening of small-conductance Ca2+ release-activated Ca2+ channels.
Topics: Animals; Automation; Calcium; Cell Line; Dose-Response Relationship, Drug; Egtazic Acid; Electrophysiology; Imidazoles; Inhibitory Concentration 50; Inositol 1,4,5-Trisphosphate; Ionomycin; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Rats; Thapsigargin | 2008 |
Localization of puff sites adjacent to the plasma membrane: functional and spatial characterization of Ca2+ signaling in SH-SY5Y cells utilizing membrane-permeant caged IP3.
Topics: Animals; Calcium Signaling; Cell Line, Tumor; Cell Membrane; Cell Membrane Permeability; Egtazic Acid; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Microscopy, Interference; Neuroblastoma; Oocytes; Patch-Clamp Techniques; Protein Transport; Xenopus | 2009 |
Inhibition of store-operated Ca2+ entry channels and K+ channels by caffeic acid phenethylester in T lymphocytes.
Topics: Caffeic Acids; Calcium; Calcium Signaling; CD28 Antigens; CD3 Complex; Cell Line; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electrophysiology; Humans; Inositol 1,4,5-Trisphosphate; Interleukin-2; Ionomycin; Jurkat Cells; Kidney; Patch-Clamp Techniques; Phenylethyl Alcohol; Phytohemagglutinins; Potassium Channels, Voltage-Gated; T-Lymphocytes; Thapsigargin; Time Factors | 2009 |
Endothelium-independent vasodilation induced by kolaviron, a biflavonoid complex from Garcinia kola seeds, in rat superior mesenteric arteries.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channels, L-Type; Charybdotoxin; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Flavonoids; Garcinia kola; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle Contraction; Neurotoxins; Organ Culture Techniques; Phenylephrine; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Wistar; Seeds; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
VEGF-induced retinal angiogenic signaling is critically dependent on Ca²⁺ signaling by Ca²⁺/calmodulin-dependent protein kinase II.
Topics: Animals; Blotting, Western; Boron Compounds; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cattle; Cell Movement; Cell Proliferation; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estrenes; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Neovascularization, Physiologic; Oxazoles; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidinones; Retinal Vessels; Type C Phospholipases; Vascular Endothelial Growth Factor A | 2011 |
Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin.
Topics: Animals; Calcium; Calcium Channels; Catecholamines; Cell Membrane; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Gene Expression Regulation, Enzymologic; Humans; Inositol 1,4,5-Trisphosphate; Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Rats; Secretin; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Type C Phospholipases; Tyrosine 3-Monooxygenase | 2011 |
Custom-made modification of a commercial confocal microscope to photolyze caged compounds using the conventional illumination module and its application to the observation of Inositol 1,4,5-trisphosphate-mediated calcium signals.
Topics: Animals; Calcium; Calcium Signaling; Egtazic Acid; Equipment Design; Inositol 1,4,5-Trisphosphate; Linear Models; Microscopy, Confocal; Oocytes; Photolysis; Ultraviolet Rays; Xenopus laevis | 2011 |
Functional role of the calmodulin- and inositol 1,4,5-trisphosphate receptor-binding (CIRB) site of TRPC6 in human platelet activation.
Topics: Antibodies, Monoclonal; Binding Sites; Blood Platelets; Blotting, Western; Calcium; Calmodulin; Chelating Agents; Egtazic Acid; Electroporation; Enzyme Inhibitors; Humans; Immunoprecipitation; Inositol 1,4,5-Trisphosphate; Platelet Activation; Platelet Aggregation; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Thapsigargin; Thrombin; TRPC Cation Channels; TRPC6 Cation Channel | 2011 |
The involvement of calcium carriers and of the vacuole in the glucose-induced calcium signaling and activation of the plasma membrane H(+)-ATPase in Saccharomyces cerevisiae cells.
Topics: Boron Compounds; Calcium; Calcium Signaling; Cell Membrane; Egtazic Acid; Enzyme Activation; Extracellular Space; Glucose; Inositol 1,4,5-Trisphosphate; Models, Biological; Mutation; Nifedipine; Proton-Translocating ATPases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; TRPC Cation Channels; Vacuoles | 2012 |
Ca2+ homeostasis in the endoplasmic reticulum measured with a new low-Ca2+-affinity targeted aequorin.
Topics: Aequorin; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Female; HeLa Cells; Homeostasis; Humans; Inositol 1,4,5-Trisphosphate; Mitochondrial Membranes; Thapsigargin | 2013 |
Mid-range Ca2+ signalling mediated by functional coupling between store-operated Ca2+ entry and IP3-dependent Ca2+ release.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cytoplasm; Egtazic Acid; Endoplasmic Reticulum; Female; Green Fluorescent Proteins; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Membrane Microdomains; Membrane Potentials; Oocytes; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Subcellular Fractions; Xenopus laevis | 2014 |
Ca²⁺ images obtained in different experimental conditions shed light on the spatial distribution of IP₃ receptors that underlie Ca²⁺ puffs.
Topics: Algorithms; Aniline Compounds; Animals; Calcium; Calcium Signaling; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Microscopy, Confocal; Oocytes; Xanthenes; Xenopus | 2015 |
Redistribution of subcellular calcium and its effect on apoptosis in primary cultures of rat proximal tubular cells exposed to lead.
Topics: Animals; Apoptosis; Boron Compounds; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Cytoplasm; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Homeostasis; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kidney Tubules, Proximal; Microscopy, Confocal; Microscopy, Fluorescence; Mitochondria; Organometallic Compounds; Primary Cell Culture; Rats, Sprague-Dawley; Time Factors | 2015 |
Two functionally distinct pools of eNOS in endothelium are facilitated by myoendothelial junction lipid composition.
Topics: Biological Transport; Bradykinin; Calcium; Calcium Signaling; Cell Communication; Coculture Techniques; Cyclic GMP; Diglycerides; Egtazic Acid; Endoplasmic Reticulum; Endothelial Cells; Gap Junctions; Gene Expression Regulation; Humans; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type III; Oxazoles; Phenylephrine; Phosphatidylserines; Phosphorylation; Primary Cell Culture; Protein Kinase C; Protein Kinase Inhibitors; Thapsigargin | 2016 |