egtazic acid has been researched along with cyclosporine in 99 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 38 (38.38) | 18.2507 |
| 2000's | 48 (48.48) | 29.6817 |
| 2010's | 13 (13.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Smyth, MJ | 1 |
| Bernardi, P; Szabó, I; Zoratti, M | 1 |
| Degiannis, D; Hornung, N; Raska, K; Raskova, J | 1 |
| Baldari, CT; Heguy, A; Macchia, G; Melli, M; Telford, JL | 1 |
| Bernardi, P; Colonna, R; Costantini, P; Nicolli, A; Petronilli, V | 1 |
| Antoni, FA; Barnard, RJ; Hernando, F; Shipston, MJ | 1 |
| Bar-Tana, J; Hermesh, O; Kalderon, B | 1 |
| McCaffrey, PG; Perrino, BA; Rao, A; Soderling, TR | 1 |
| Baumgartner, D; Richter, C; Schlegel, J; Schweizer, M | 1 |
| Bertrand, R; Jenkins, J; Pommier, Y; Solary, E | 1 |
| Kumbar, U; Maddaiah, VT | 1 |
| Johnson, GV; Norman, SG | 1 |
| Mikhaylova, LM; Starkov, AA | 1 |
| Farber, JL; Hoek, JB; Pastorino, JG; Snyder, JW | 1 |
| Copeland, KF; Goudsmit, J; Haaksma, AG; Heeney, JL | 1 |
| Gogvadze, V; Richter, C | 1 |
| Murphy, MP; Porteous, CM; Reichman, N | 1 |
| Bernardi, P; Petronilli, V; Veronese, P | 1 |
| Larson, TG; Nuss, DL | 1 |
| Clark, WR; Ratner, A | 1 |
| Baldari, CT; Heguy, A; Telford, JL | 1 |
| Debska, G; Lenartowicz, E; Wudarczyk, J | 1 |
| Frosch, KH; Kalden, JR; Lane, P; Manger, B; Nüsslein, HG; Woith, W | 1 |
| Kristal, BS; Park, BK; Yu, BP | 1 |
| Schwinzer, R; Siefken, R | 1 |
| Bevan, S; Boddeke, HW; Docherty, RJ; Yeats, JC | 1 |
| Chouaib, S; Lehmann, V; Shatrov, VA | 1 |
| Dedukhova, VI; Malkevitch, NV; Simonian, RA; Skulachev, VP; Starkov, AA | 1 |
| Alpini, G; Alvaro, D; Bassotti, C; Benedetti, A; Fraioli, F; Francia, C; Glaser, SS; Jezequel, AM; Le Sage, G; Marucci, L; Romeo, R | 1 |
| Beyaert, R; Buurman, WA; Declercq, W; Denecker, G; Fiers, W; Grooten, J; Penning, LC; Vandenabeele, P | 1 |
| Greengard, P; Nishi, A; Snyder, GL | 1 |
| Hakoda, S; Takeyama, N; Tanaka, T | 1 |
| Reinach, PS; Torres-zamorano, V; Wu, X; Yang, H | 1 |
| Grégoire, M; Juin, P; LeCabellec, MT; Meflah, K; Tremblais, K; Vallette, FM | 1 |
| Connern, C; Friberg, H; Halestrap, AP; Wieloch, T | 1 |
| Aikawa, R; Komuro, I; Nagai, R; Saito, S; Shiojima, I; Yazaki, Y | 1 |
| Baldamus, CA; Egink, G; Marsen, TA; Suckau, G; Weber, F | 1 |
| Almawi, WY; Assi, JW; Chudzik, DM; Lazarovits, AI | 1 |
| Okunuki, H; Onose, J; Sawada, J; Teshima, R | 1 |
| Hur, GH; Kim, YB; Lee, WS; Park, KJ; Park, YM; Shin, S | 1 |
| Ong, CN; Shen, HM; Yang, CF | 1 |
| Fiskum, G; Kowaltowski, AJ; Russell, JT; Smaili, SS | 1 |
| Endo, H; Hamamoto, T; Inoki, Y; Kagawa, Y; Kajimoto, T; Kawase, M; Kawase, Y; Kinouchi, T; Miura, T; Tsuji, S; Yoshida, Y | 1 |
| Ahn, JO; Bandyopadhyay, A; Kim, DH; Shin, DW | 1 |
| Fong, CW; Lin, SC; Neo, SY; Zhang, Y | 1 |
| Gu, Z; Jiang, Q; Jing, G; Zhang, G | 1 |
| Ames, BN; Gogvadze, V; Klein, SD; Richter, C; Shigenaga, M | 1 |
| Bodrova, ME; Dedukhova, VI; Mokhova, EN; Samartsev, VN | 1 |
| Domschke, W; Gunzel, D; Lerch, MM; Mooren, FC; Schlue, WR; Singh, J; Turi, S | 1 |
| Arora, PD; Ganss, B; McCulloch, CA; Silvestri, L; Sodek, J | 1 |
| Sokolove, PM; Sultan, A | 1 |
| Brailovskaya, IV; Mokhova, EN; Starkov, AA | 1 |
| Bernardes, CF; Castilho, RF; Fagian, MM; Meyer-Fernandes, JR; Vercesi, AE | 1 |
| Bouchard, MJ; Schneider, RJ; Wang, LH | 1 |
| Raia, FJ; Valhmu, WB | 1 |
| Lemeshko, VV | 1 |
| Greengard, P; Liu, F; Nairn, AC; Virshup, DM | 1 |
| Brunati, AM; Clari, G; Salvi, M; Toninello, A | 1 |
| Bakowski, D; Glitsch, MD; Parekh, AB | 1 |
| Bolatto, C; Cantera, R; Chifflet, S; Megighian, A | 1 |
| Lum, MG; Nagley, P | 1 |
| Azarashvili, T; Evtodienko, Y; Krestinina, O; Odinokova, I; Reiser, G | 1 |
| Bracht, A; Ishii-Iwamoto, EL; Kelmer-Bracht, AM; Salgueiro-Pagadigorria, CL | 1 |
| Bénitah, JP; Perrier, E; Perrier, R; Richard, S | 1 |
| Arima, H; Asai, M; Ito, M; Iwasaki, Y; Mutsuga-Nakayama, N; Oiso, Y; Takano, K; Yoshida, M | 1 |
| Richter, C; Salvi, M; Schweizer, M; Toninello, A | 1 |
| Guirland, C; Ming, GL; Wen, Z; Zheng, JQ | 1 |
| Bechara, EJ; Dutra, F | 1 |
| Conte, MA; Kamel, S; Louandre, C; Massy, Z; Mazière, C; Mazière, JC; Morlière, P | 1 |
| Högger, P; Timmermann, M | 1 |
| Andreu, GL; Curti, C; Delgado, R; Velho, JA; Vercesi, AE | 1 |
| Antonicelli, F; Conte, MA; Gomilla, C; Hornebeck, W; Louandre, C; Mazière, C; Mazière, JC; Morlière, P; Santus, R | 1 |
| Cavalheiro, RA; Curti, C; Delgado, R; Dorta, DJ; Pardo-Andreu, GL; Santos, AC; Vercesi, AE | 1 |
| Clements, JM; Vanhoose, AM; Winder, DG | 1 |
| Auborn, KJ; Carter, TH; Evans, JF; Rabinowitz, D; Savino, JA | 1 |
| Boelsterli, UA; Gupta, R; Lim, MS; Lim, PL | 1 |
| Belosludtsev, KN; Belosludtseva, NV; Gritsenko, EN; Khodorov, BI; Mironova, GD; Saris, NE | 1 |
| Binder, BR; Hofer, E; Lucerna, M; Mechtcheriakova, D; Schabbauer, G; Schweighofer, B | 1 |
| Armstrong, JS; Lu, C | 1 |
| Racay, P | 1 |
| Golstein, P; Kosta, A; Lam, D; Luciani, MF | 1 |
| Cho, HJ; Huh, K; Jin, SM; Mook-Jung, I; Youn, HD | 1 |
| Boelsterli, UA; Latchoumycandane, C; Pun, PB; Siu, WP | 1 |
| Hayakawa, K; Nakagawa, S; Watanabe, T; Yoneda, A | 1 |
| Cai, F; Chen, J; Chen, JG; Hu, ZL; Liu, J; Wang, F; Wang, W; Yang, YJ | 1 |
| Cook, IH; Critchley, HO; Evans, J; Jabbour, HN; Maldonado-Pérez, D; Sales, KJ | 1 |
| Chikazu, D; Drissi, H; Herschman, HR; Huang, H; Kream, BE; Pilbeam, CC; Voznesensky, OS | 1 |
| Friis, UG; Gooch, JL; Hansen, PB; Holmgaard, L; Jensen, BL; Madsen, K; Skøtt, O | 1 |
| Brunner, C; Eitelhuber, A; Krappmann, D; Marienfeld, RB; Marienfeld, U; Palkowitsch, L | 1 |
| Kakkar, P; Pandey, PK; Singh, BK; Tripathi, M | 1 |
| Abramov, AY; Duchen, MR | 1 |
| Castilho, RF; Ronchi, JA; Vercesi, AE | 1 |
| Nair, SS; Ransdell, JL; Schulz, DJ | 1 |
| Bonventre, JV; Cravatt, BF; Ewing, H; Gelb, MH; Ghosh, M; Hsu, KL; Lee, H; Leslie, CC; Yun, B | 1 |
| Anderson, RA; Panickar, KS; Qin, B | 1 |
| Hansen, SH; Skonberg, C; Syed, M | 1 |
| Brunner-Weinzierl, MC; Hartig, R; Jorch, G; Krause, H; Röhl, FW; Schmiedeberg, K | 1 |
| Dorniak, PL; Gangwar, R; Meena, AS; Nagaraja, AS; Pallikuth, S; Rao, R; Shukla, PK; Sood, A; Waters, CM | 1 |
99 other study(ies) available for egtazic acid and cyclosporine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Mechanisms of cytotoxicity used by human peripheral blood T-cell subsets.
Topics: Bucladesine; CD4 Antigens; CD8 Antigens; Cholera Toxin; Cycloheximide; Cyclosporine; Cytotoxicity, Immunologic; Dactinomycin; Egtazic Acid; Emetine; Humans; Lymphocyte Activation; Mitomycin; T-Lymphocyte Subsets; Tumor Necrosis Factor-alpha | 1992 |
Modulation of the mitochondrial megachannel by divalent cations and protons.
Topics: Animals; Barium; Calcium; Cations, Divalent; Cyclosporine; Egtazic Acid; Electric Conductivity; Hydrogen-Ion Concentration; Ion Channels; Kinetics; Magnesium; Mitochondria, Liver; Mitomycin; Rats | 1992 |
IL-2 responsiveness of lectin-induced lymphoblasts: soluble IL-2 receptor release and differential in vitro effects of immunosuppressants.
Topics: CD4 Antigens; CD8 Antigens; Cyclosporine; Egtazic Acid; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Prednisolone; Receptors, Interleukin-2; Recombinant Proteins; T-Lymphocytes; Verapamil | 1992 |
Cyclosporin A blocks calcium-dependent pathways of gene activation.
Topics: Calcium; Cyclosporine; Egtazic Acid; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-2; Phytohemagglutinins; Promoter Regions, Genetic; Receptors, Immunologic; Receptors, Interleukin-1; Signal Transduction; Simian virus 40; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured | 1991 |
Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A.
Topics: Amino Acid Isomerases; Animals; Arsenites; Calcium; Carrier Proteins; Cyclosporine; Egtazic Acid; Intracellular Membranes; Ion Channels; Membrane Potentials; Mitochondria, Liver; Peptidylprolyl Isomerase; Permeability; Rats; Signal Transduction | 1994 |
Glucocorticoid negative feedback in pituitary corticotropes. Pivotal role for calcineurin inhibition of adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adrenocorticotropic Hormone; Animals; Calcimycin; Calcineurin; Calcium; Calmodulin-Binding Proteins; Cell Line; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclosporine; Dexamethasone; Dose-Response Relationship, Drug; Egtazic Acid; Feedback; Mice; Nimodipine; Phosphoprotein Phosphatases; Pituitary Gland; Pituitary Neoplasms; Tacrolimus; Tumor Cells, Cultured | 1994 |
Mitochondrial permeability transition is induced by in vivo thyroid hormone treatment.
Topics: Animals; Calcium; Cyclosporine; Egtazic Acid; Energy Metabolism; Hypothyroidism; Male; Mitochondria, Liver; NADP Transhydrogenases; Permeability; Rats; Reference Values; Temperature; Thyroid Hormones; Triiodothyronine | 1995 |
NF-ATp, a T lymphocyte DNA-binding protein that is a target for calcineurin and immunosuppressive drugs.
Topics: Amino Acid Isomerases; Animals; Calcineurin; Calcium; Calmodulin-Binding Proteins; Carrier Proteins; Cell Nucleus; Clone Cells; Cyclosporine; DNA-Binding Proteins; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Immunosuppressive Agents; Mice; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Phosphoproteins; T-Lymphocytes; Tacrolimus; Tacrolimus Binding Proteins | 1993 |
Sensitivity of mitochondrial peptidyl-prolyl cis-trans isomerase, pyridine nucleotide hydrolysis and Ca2+ release to cyclosporine A and related compounds.
Topics: Amino Acid Isomerases; Animals; Calcium; Carrier Proteins; Cyclosporine; Egtazic Acid; Mitochondria, Liver; Peptidylprolyl Isomerase; Peroxides; Purine Nucleotides; Rats; Tacrolimus; tert-Butylhydroperoxide | 1993 |
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1993 |
Membrane permeability transition promoted by phosphate enhances 1-anilino-8-naphthalene sulfonate fluorescence in calcium-loaded liver mitochondria.
Topics: Acetates; Acetic Acid; Adenosine Diphosphate; Anilino Naphthalenesulfonates; Animals; Calcimycin; Calcium; Cyclosporine; Egtazic Acid; Fluorescence; Fluorescent Dyes; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Osmolar Concentration; Permeability; Phosphates; Rats; Rats, Sprague-Dawley; Ruthenium Red | 1993 |
Compromised mitochondrial function results in dephosphorylation of tau through a calcium-dependent process in rat brain cerebral cortical slices.
Topics: Adenosine Triphosphate; Animals; Calcineurin; Calcium; Calmodulin-Binding Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cerebral Cortex; Cyclosporine; Egtazic Acid; In Vitro Techniques; Male; Mitochondria; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Sprague-Dawley; tau Proteins | 1994 |
Ca(2+)-loading modulates potencies of cyclosporin A, Mg2+ and ADP to recouple permeabilized rat liver mitochondria.
Topics: 2,4-Dinitrophenol; Adenosine Diphosphate; Animals; Atractyloside; Calcium Chloride; Cyclosporine; Dinitrophenols; Egtazic Acid; Magnesium Sulfate; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Onium Compounds; Organophosphorus Compounds; Permeability; Rats | 1994 |
Ca2+ depletion prevents anoxic death of hepatocytes by inhibiting mitochondrial permeability transition.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Death; Cell Hypoxia; Cyclosporine; Egtazic Acid; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Palmitoyl Coenzyme A; Permeability; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Rotenone | 1995 |
Calcium-mediated inhibition of phorbol ester and Tax trans-activation of the human T cell leukaemia virus type 1.
Topics: beta-Galactosidase; Calcium; Cell Line, Transformed; Cyclosporine; Egtazic Acid; Gene Expression Regulation, Viral; Gene Products, tax; Genes, pX; HTLV-I Antigens; Human T-lymphotropic virus 1; Humans; Ionomycin; Repetitive Sequences, Nucleic Acid; Retroviridae Proteins, Oncogenic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1994 |
Cyclosporine A protects mitochondria in an in vitro model of hypoxia/reperfusion injury.
Topics: Adenosine Diphosphate; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclosporine; Egtazic Acid; Hypoxia; Kinetics; Mitochondria, Liver; Oxygen Consumption; Rats; Reperfusion Injury | 1993 |
Cyclosporin A blocks 6-hydroxydopamine-induced efflux of Ca2+ from mitochondria without inactivating the mitochondrial inner-membrane pore.
Topics: Animals; Calcium; Cyclosporine; Egtazic Acid; Female; Intracellular Membranes; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxidopamine; Rats; Rats, Wistar | 1994 |
Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore. I. Evidence for two separate Me2+ binding sites with opposing effects on the pore open probability.
Topics: Animals; Binding Sites; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyclosporine; Dibucaine; Egtazic Acid; Hydrogen-Ion Concentration; Intracellular Membranes; Kinetics; Magnesium; Membrane Potentials; Mitochondria, Liver; Permeability; Probability; Rats; Trifluoperazine | 1993 |
Cyclophilin-dependent stimulation of transcription by cyclosporin A.
Topics: Amino Acid Isomerases; Carrier Proteins; Cycloheximide; Cyclosporine; Drug Resistance, Microbial; Egtazic Acid; Genes, Fungal; Laccase; Mutagenesis; Neomycin; Oxidoreductases; Peptidylprolyl Isomerase; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; Transcription, Genetic; Ultraviolet Rays; Xylariales | 1993 |
Role of TNF-alpha in CD8+ cytotoxic T lymphocyte-mediated lysis.
Topics: Animals; CD8 Antigens; Clone Cells; Cyclosporine; Cytotoxicity, Immunologic; Egtazic Acid; Female; Flow Cytometry; Immunity, Cellular; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; T-Lymphocytes, Cytotoxic; Tumor Necrosis Factor-alpha | 1993 |
Calcium dependent activation of the NF-AT transcription factor by p59fyn.
Topics: Calcimycin; Calcium; Chloramphenicol O-Acetyltransferase; Cyclosporine; DNA-Binding Proteins; Egtazic Acid; Humans; NFATC Transcription Factors; Nuclear Proteins; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1993 |
Relation between the activities reducing disulfides and the protection against membrane permeability transition in rat liver mitochondria.
Topics: Animals; Cyclosporine; Diphosphates; Disulfides; Dithionitrobenzoic Acid; Egtazic Acid; Glutathione Reductase; Intracellular Membranes; Kinetics; Magnesium; Mitochondria, Liver; Mitochondrial Swelling; Oxidation-Reduction; Permeability; Rats; Thioredoxin-Disulfide Reductase | 1996 |
Increase of intracellular calcium is the essential signal for the expression of CD40 ligand.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Calcium; CD28 Antigens; CD3 Complex; CD40 Ligand; Cell Separation; Cyclosporine; Egtazic Acid; Enzyme Activation; Gene Expression Regulation; Humans; Intracellular Fluid; Ionomycin; Ionophores; Lymphocyte Activation; Membrane Glycoproteins; Mitogens; Protein Kinase C; Receptors, Interleukin-2; Receptors, Transferrin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition.
Topics: Aldehydes; Animals; Calcium; Cyclosporine; Egtazic Acid; Glutathione; Lipid Peroxidation; Male; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Stress; Permeability; Rats; Rats, Inbred F344 | 1996 |
CD45RA+ and CD45RO+ T cells differ in susceptibility to cyclosporin A mediated inhibition of interleukin-2 production.
Topics: Antibodies, Monoclonal; CD4-Positive T-Lymphocytes; Cyclosporine; Egtazic Acid; Humans; In Vitro Techniques; Interleukin-2; Leukocyte Common Antigens; Receptors, Antigen, T-Cell, alpha-beta; Signal Transduction | 1996 |
Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcineurin; Calcium; Calmodulin-Binding Proteins; Capsaicin; Cells, Cultured; Chelating Agents; Cyclosporine; Drug Resistance; Egtazic Acid; Enzyme Inhibitors; Evoked Potentials; Ganglia, Spinal; Ion Channel Gating; Ion Channels; Ligands; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Rats | 1996 |
Sphingosine-1-phosphate mobilizes intracellular calcium and activates transcription factor NF-kappa B in U937 cells.
Topics: Antioxidants; Butylated Hydroxyanisole; Calcium; Chelating Agents; Cyclosporine; DNA Probes; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fluorescent Dyes; Genes, Reporter; Humans; Indoles; Leukemia, Myeloid; Luciferases; Lysophospholipids; NF-kappa B; Sphingolipids; Sphingosine; Thapsigargin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Thyroxine induces cyclosporin A-insensitive, Ca2+-dependent reversible permeability transition pore in rat liver mitochondria.
Topics: Adenosine Diphosphate; Animals; Calcium; Cyclosporine; Egtazic Acid; Intracellular Membranes; Ionophores; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Niacinamide; Nigericin; Permeability; Rats; Thyroxine; Uncoupling Agents | 1997 |
Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions.
Topics: Acetylcholine; Animals; Antiporters; Bicarbonates; Bile Ducts, Intrahepatic; Calcineurin Inhibitors; Chelating Agents; Chloride-Bicarbonate Antiporters; Chlorides; Cyclic AMP; Cyclosporine; Diphenylacetic Acids; Egtazic Acid; Fluorescent Antibody Technique, Indirect; Hydrogen-Ion Concentration; In Vitro Techniques; Microscopy, Immunoelectron; Muscarinic Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Secretin; Staurosporine; Tacrolimus | 1997 |
Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma.
Topics: Animals; Apoptosis; Aurintricarboxylic Acid; Calcineurin; Calcium; Chlorides; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Hybridomas; Interleukin-1; Mice; Rats; T-Lymphocytes; Tacrolimus; Time Factors; Tumor Necrosis Factor-alpha; Zinc Compounds | 1997 |
Bidirectional regulation of DARPP-32 phosphorylation by dopamine.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antipsychotic Agents; Calcineurin; Calcineurin Inhibitors; Calcium; Chelating Agents; Colforsin; Corpus Striatum; Cyclosporine; Dopamine; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Egtazic Acid; Fenoldopam; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurotoxins; Nucleus Accumbens; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Quinpirole; Raclopride; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Salicylamides; Signal Transduction; Tetrodotoxin | 1997 |
Reoxygenation-induced mitochondrial damage is caused by the Ca2+-dependent mitochondrial inner membrane permeability transition.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbon Radioisotopes; Cell Membrane Permeability; Cyclosporine; Egtazic Acid; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxygen; Rats; Rats, Wistar; Reactive Oxygen Species; Ruthenium Red; Sucrose | 1998 |
ETA receptor mediated inhibition of intracellular pH regulation in cultured bovine corneal epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclosporine; Diuretics; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epithelium, Corneal; Hydrogen-Ion Concentration; Immunosuppressive Agents; Intracellular Fluid; Naphthalenes; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Endothelin; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1998 |
Potentiation of apoptosis by mitochondria in a cell-free system.
Topics: Animals; Apoptosis; Calcium; Caspase 3; Caspase Inhibitors; Caspases; Cell-Free System; Cells, Cultured; Chelating Agents; Cyclosporine; Cysteine Proteinase Inhibitors; Cytochrome c Group; Egtazic Acid; Enzyme Activation; Liver; Mitochondria, Liver; Proto-Oncogene Proteins c-bcl-2; Rats | 1998 |
Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability.
Topics: Adenine Nucleotides; Animals; Brain; Cerebellum; Cerebral Cortex; Cyclosporine; Egtazic Acid; Hippocampus; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Mitochondria; Mitochondrial Swelling; Organ Specificity; Oxygen Consumption; Permeability; Rats; Rats, Wistar | 1999 |
Endothelin-1 induces expression of fetal genes through the interleukin-6 family of cytokines in cardiac myocytes.
Topics: Animals; Animals, Newborn; Antigens, CD; Atrial Natriuretic Factor; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclosporine; Cytokine Receptor gp130; Cytokines; Egtazic Acid; Endothelin-1; Gene Expression Regulation, Developmental; Growth Inhibitors; Heart; Interleukin-6; Ionomycin; Ionophores; Leukemia Inhibitory Factor; Lymphokines; Membrane Glycoproteins; Mutation; Myocardium; Myosin Heavy Chains; Natriuretic Peptide, Brain; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
Cyclosporin A induces prepro endothelin-1 gene transcription in human endothelial cells.
Topics: Animals; Blotting, Northern; Calcium; Cells, Cultured; Chelating Agents; Cyclosporine; Egtazic Acid; Endothelin-1; Endothelium; Female; Fluorometry; Galactosidases; Genes, Reporter; Humans; Immunosuppressive Agents; Luciferases; Plasmids; Pregnancy; Rats; RNA, Messenger; Transfection; Umbilical Veins | 1999 |
Opposing effects of rapamycin and cyclosporin A on activation-induced Ca(2+) release.
Topics: Animals; Calcium; Cell Division; Cell Line; Chelating Agents; Concanavalin A; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Immunosuppressive Agents; Ionomycin; Kinetics; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocytes; Sirolimus; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Effect of Ca(2+) ATPase inhibitors on MCP-1 release from bone marrow-derived mast cells and the involvement of p38 MAP kinase activation.
Topics: Animals; Blotting, Western; Bone Marrow Cells; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Chemokine CCL2; Cyclosporine; Dactinomycin; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Female; Hydroquinones; Indoles; Mast Cells; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2000 |
Intracellular calcium antagonist protects cultured peritoneal macrophages against anthrax lethal toxin-induced cytotoxicity.
Topics: Animals; Anthrax; Antifungal Agents; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Calcium; Cells, Cultured; Chelating Agents; Cyclosporine; Dantrolene; Egtazic Acid; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Mitochondria; Muscle Relaxants, Central; Virulence | 2000 |
Intracellular thiol depletion causes mitochondrial permeability transition in ebselen-induced apoptosis.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Azoles; Buthionine Sulfoximine; Calcium; Caspase 3; Caspase 9; Caspases; Cyclosporine; Cytochrome c Group; Egtazic Acid; Humans; Isoindoles; Membrane Potentials; Mitochondria, Liver; Organoselenium Compounds; Permeability; Sulfhydryl Compounds; Superoxide Dismutase; Superoxides; Tumor Cells, Cultured | 2000 |
Elevation of resting mitochondrial membrane potential of neural cells by cyclosporin A, BAPTA-AM, and bcl-2.
Topics: Animals; Chelating Agents; Cyclosporine; Egtazic Acid; Humans; Hypothalamus; Intracellular Membranes; Membrane Potentials; Mitochondria; Neurons; PC12 Cells; Permeability; Proto-Oncogene Proteins c-bcl-2; Rats; tert-Butylhydroperoxide; Tumor Cells, Cultured | 2000 |
Ganglioside GD3 and its mimetics induce cytochrome c release from mitochondria.
Topics: Animals; Blotting, Western; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell-Free System; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Dose-Response Relationship, Drug; Egtazic Acid; Gangliosides; Ion Channels; Leupeptins; Membrane Proteins; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Molecular Mimicry; Oligomycins; Rats | 2000 |
Calcineurin regulates ryanodine receptor/Ca(2+)-release channels in rat heart.
Topics: Animals; Animals, Newborn; Blotting, Western; Calcineurin; Calcium; Calcium Channels; Cells, Cultured; Chelating Agents; Cholic Acids; Cyclosporine; Detergents; Egtazic Acid; Fluorescent Antibody Technique; Immunosuppressive Agents; Insecticides; Microscopy, Confocal; Myocardium; Nitriles; Phosphorylation; Precipitin Tests; Protein Binding; Pyrethrins; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sirolimus; Tacrolimus; Tacrolimus Binding Proteins; Time Factors | 2000 |
Specific induction of RGS16 (regulator of G-protein signalling 16) mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor alpha in a calcium-sensitive manner.
Topics: Androstadienes; Bucladesine; Calcimycin; Calcineurin; Calcium; Calcium Signaling; Cyclosporine; DNA-Binding Proteins; Egtazic Acid; Enzyme Activation; Humans; Kinetics; Mitogen-Activated Protein Kinases; NFATC Transcription Factors; Nuclear Proteins; Protein Kinase C; Proteins; RGS Proteins; RNA, Messenger; Tacrolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin | 2000 |
N-methyl-D-aspartate receptor activation results in regulation of extracellular signal-regulated kinases by protein kinases and phosphatases in glutamate-induced neuronal apototic-like death.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclosporine; Dizocilpine Maleate; Egtazic Acid; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Nifedipine; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Effect of ebselen on Ca2+ transport in mitochondria.
Topics: Animals; Antioxidants; Azoles; Calcium; Calcium Channels; Calcium-Binding Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclosporine; Egtazic Acid; Glutathione; Isoindoles; Ketones; Kinetics; Mitochondria, Liver; Mitochondrial Swelling; Organoselenium Compounds; Oxidative Phosphorylation; Oxygen Consumption; Permeability; Rats; Ruthenium Red; Uncoupling Agents | 2000 |
Role of the ADP/ATP-antiporter in fatty acid-induced uncoupling of Ca2+-loaded rat liver mitochondria.
Topics: Animals; Atractyloside; Calcium; Cyclosporine; Egtazic Acid; In Vitro Techniques; Membrane Potentials; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Models, Biological; Myristic Acid; Nigericin; Rats; Uncoupling Agents | 2000 |
Calcium-magnesium interactions in pancreatic acinar cells.
Topics: Animals; Calcium; Calcium Signaling; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Chelating Agents; Cholecystokinin; Cyclosporine; Edetic Acid; Egtazic Acid; Enzyme Inhibitors; Fluorescent Dyes; Image Processing, Computer-Assisted; In Vitro Techniques; Ion Transport; Ionophores; Magnesium; Male; Membrane Potentials; Mice; Pancreas; Spectrometry, Fluorescence; Thapsigargin | 2001 |
Mechanism of cyclosporin-induced inhibition of intracellular collagen degradation.
Topics: Animals; Binding Sites; Blotting, Western; Calcium; Cells, Cultured; Chelating Agents; Collagen; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Humans; Kinetics; Membrane Potentials; Mitochondria; Phagocytosis; Rats; Serum Albumin, Bovine; Signal Transduction; Temperature; Thapsigargin; Time Factors | 2001 |
Palmitic acid opens a novel cyclosporin A-insensitive pore in the inner mitochondrial membrane.
Topics: Animals; Calcium; Cations; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Fatty Acids, Nonesterified; Intracellular Membranes; Lysophospholipids; Male; Membrane Potentials; Mitochondria; Mitochondria, Liver; Models, Biological; Palmitic Acid; Protons; Rats; Rats, Sprague-Dawley; Serum Albumin; Strontium | 2001 |
Ascorbate and low concentrations of FeSO4 induce Ca2+-dependent pore in rat liver mitochondria.
Topics: Animals; Ascorbic Acid; Calcium Channels; Cyclosporine; Egtazic Acid; Ferrous Compounds; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Stress; Permeability; Rats | 2001 |
Suramin inhibits respiration and induces membrane permeability transition in isolated rat liver mitochondria.
Topics: Adenosine Diphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane Permeability; Cell Respiration; Chelating Agents; Cyclosporine; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Ethylmaleimide; Intracellular Membranes; Magnesium; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxygen Consumption; Rats; Rats, Wistar; Sulfhydryl Reagents; Suramin; Trypanocidal Agents | 2001 |
Calcium signaling by HBx protein in hepatitis B virus DNA replication.
Topics: Calcium; Calcium Channels; Calcium Signaling; Cyclosporine; Cytosol; DNA Replication; DNA, Viral; Egtazic Acid; Enzyme Activation; Focal Adhesion Kinase 2; Genome, Viral; Hepatitis B virus; Humans; Mitochondria; Phosphorylation; Plasmids; Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Trans-Activators; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Viral Regulatory and Accessory Proteins; Virus Replication | 2001 |
myo-Inositol 1,4,5-trisphosphate and Ca(2+)/calmodulin-dependent factors mediate transduction of compression-induced signals in bovine articular chondrocytes.
Topics: Aggrecans; Alkaloids; Animals; Benzophenanthridines; Benzylamines; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cartilage; Cattle; Chondrocytes; Cyclic AMP; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix Proteins; Indoles; Inositol 1,4,5-Trisphosphate; Lectins, C-Type; Maleimides; Models, Biological; Phenanthridines; Protein Kinase C; Proteoglycans; RNA, Messenger; Signal Transduction; Sulfonamides; Thapsigargin; Time Factors | 2002 |
Biphasic oxidation of mitochondrial NAD(P)H.
Topics: Adenosine Triphosphate; Animals; Chelating Agents; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Electron Transport; Enzyme Inhibitors; Intracellular Membranes; Membrane Potentials; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Permeability; Rats; tert-Butylhydroperoxide | 2002 |
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors.
Topics: Animals; Calcineurin; Casein Kinases; Chelating Agents; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cyclosporine; Dopamine and cAMP-Regulated Phosphoprotein 32; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Mice; Neostriatum; Nerve Tissue Proteins; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Kinases; Pyrrolidinones; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Type C Phospholipases | 2002 |
Interaction of genistein with the mitochondrial electron transport chain results in opening of the membrane transition pore.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Bongkrekic Acid; Chelating Agents; Cyclosporine; Dithiothreitol; Egtazic Acid; Electron Transport; Enzyme Inhibitors; Ethylmaleimide; Genistein; Indicators and Reagents; Membrane Potentials; Mitochondria, Liver; Molecular Structure; Oxidation-Reduction; Rats; Ruthenium Red; Uncoupling Agents | 2002 |
Store-operated Ca2+ entry depends on mitochondrial Ca2+ uptake.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antioxidants; Calcium; Calcium Channels; Cell Line, Tumor; Cyclosporine; Egtazic Acid; Hydrogen-Ion Concentration; Membrane Potentials; Mitochondria; Nitric Oxide; Oxygen; Patch-Clamp Techniques; Rats; Ruthenium Red; Thapsigargin; Time Factors | 2002 |
Synaptic activity modifies the levels of Dorsal and Cactus at the neuromuscular junction of Drosophila.
Topics: Anesthetics, Local; Animals; Calcium; Cell Adhesion Molecules, Neuronal; Chelating Agents; Cyclosporine; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Indoleacetic Acids; Ionomycin; Ionophores; Larva; Microscopy, Confocal; Neuromuscular Junction; Nuclear Proteins; Phenylacetates; Phosphoproteins; Polyamines; Tetracaine; Transcription Factors | 2003 |
Two phases of signalling between mitochondria during apoptosis leading to early depolarisation and delayed cytochrome c release.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Caspases; Cell Line, Tumor; Cyclosporine; Cytochromes c; Egtazic Acid; Green Fluorescent Proteins; Humans; Luminescent Proteins; Microscopy, Confocal; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Signal Transduction; Time Factors | 2003 |
Physiological Ca2+ level and Ca2+-induced Permeability Transition Pore control protein phosphorylation in rat brain mitochondria.
Topics: Animals; Brain; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclosporine; Egtazic Acid; Imidazoles; Intracellular Membranes; Ion Channels; Isoquinolines; Membrane Potentials; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Phosphorylation; Rats; Rats, Wistar | 2003 |
Naproxen affects Ca(2+) fluxes in mitochondria, microsomes and plasma membrane vesicles.
Topics: Animals; Biological Transport, Active; Calcium; Cell Membrane; Chelating Agents; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Kinetics; Male; Microsomes; Mitochondria, Liver; Mitochondrial Swelling; Naproxen; Rats; Rats, Wistar; Ruthenium Red; Uncoupling Agents | 2004 |
Ca2+ controls functional expression of the cardiac K+ transient outward current via the calcineurin pathway.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcineurin; Calcium; Calcium Channel Agonists; Calmodulin; Cells, Cultured; Chelating Agents; Culture Media, Serum-Free; Cyclosporine; Down-Regulation; Egtazic Acid; Electrophysiology; Kinetics; Models, Biological; Nifedipine; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shal Potassium Channels; Signal Transduction; Tacrolimus; Temperature; Time Factors | 2004 |
Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Base Sequence; Calcium; Calcium Signaling; Cell Line; Cyclosporine; DNA-Binding Proteins; Egtazic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Membrane Potentials; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurons; NFATC Transcription Factors; Nuclear Proteins; Pituitary Gland, Anterior; Potassium; Promoter Regions, Genetic; Rats; Transcription Factors; Transcriptional Activation | 2004 |
Menadione induces a low conductance state of the mitochondrial inner membrane sensitive to bongkrekic acid.
Topics: Animals; Bongkrekic Acid; Calcium; Chelating Agents; Cyclosporine; Egtazic Acid; Intracellular Membranes; Mitochondria, Liver; Mitochondrial Swelling; Nucleotides; Oxidation-Reduction; Rats; Vitamin K 3 | 2004 |
A CaMKII/calcineurin switch controls the direction of Ca(2+)-dependent growth cone guidance.
Topics: Animals; Benzylamines; Calcineurin; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cyclic AMP; Cyclic GMP; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Embryo, Mammalian; Embryo, Nonmammalian; Enzyme Inhibitors; Growth Cones; Humans; Models, Neurological; Nerve Growth Factors; Netrin-1; Neurons; Nitriles; Okadaic Acid; Phosphoprotein Phosphatases; Photolysis; Protein Phosphatase 1; Pyrans; Pyrethrins; Semaphorin-3A; Spinal Cord; Spiro Compounds; Sulfonamides; Time Factors; Tumor Suppressor Proteins; Xenopus | 2004 |
Aminoacetone induces iron-mediated oxidative damage to isolated rat liver mitochondria.
Topics: Acetone; Animals; Cyclosporine; Dithiothreitol; Dose-Response Relationship, Drug; Egtazic Acid; Ferritins; Iron; Iron Chelating Agents; Magnesium; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Permeability; Phenanthrolines; Rats; Rats, Wistar; Reactive Oxygen Species | 2004 |
Oxidized low-density lipoprotein elicits an intracellular calcium rise and increases the binding activity of the transcription factor NFAT.
Topics: Antioxidants; Calcineurin Inhibitors; Calcium; Calcium Signaling; Cell Line; Chelating Agents; Cyclosporine; DNA; Egtazic Acid; Endothelial Cells; Fibroblasts; Humans; Lipoproteins, LDL; Macrophages; NFATC Transcription Factors; Protein Binding; Reactive Oxygen Species; Tacrolimus; Vitamin E | 2005 |
Oxidative stress and 8-iso-prostaglandin F(2alpha) induce ectodomain shedding of CD163 and release of tumor necrosis factor-alpha from human monocytes.
Topics: Androstadienes; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Calcium; Chelating Agents; Cyclosporine; Dinoprost; Egtazic Acid; Fluticasone; Humans; Hydrogen Peroxide; Inflammation; Monocytes; Oxidative Stress; Reactive Oxygen Species; Receptors, Cell Surface; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 2005 |
Mangiferin, a natural occurring glucosyl xanthone, increases susceptibility of rat liver mitochondria to calcium-induced permeability transition.
Topics: Adenosine Diphosphate; Animals; Calcium; Cyclosporine; Egtazic Acid; Ethylmaleimide; Glutathione; Horseradish Peroxidase; Intracellular Membranes; Lipid Peroxidation; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; NADP; Permeability; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds; Xanthones | 2005 |
Low UVA doses activate the transcription factor NFAT in human fibroblasts by a calcium-calcineurin pathway.
Topics: Antioxidants; Calcineurin; Calcineurin Inhibitors; Calcium; Cell Survival; Cells, Cultured; Cyclosporine; DNA; Dose-Response Relationship, Radiation; Egtazic Acid; Fibroblasts; Humans; NFATC Transcription Factors; Protein Binding; Signal Transduction; Tacrolimus; Ultraviolet Rays; Vitamin E | 2005 |
Vimang (Mangifera indica L. extract) induces permeability transition in isolated mitochondria, closely reproducing the effect of mangiferin, Vimang's main component.
Topics: Animals; Benzoic Acid; Catechin; Cyclosporine; Egtazic Acid; Ethylmaleimide; Gallic Acid; Horseradish Peroxidase; Hydrogen Peroxide; Mangifera; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Plant Extracts; Rats; Xanthones | 2006 |
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2006 |
Multiple, disparate roles for calcium signaling in apoptosis of human prostate and cervical cancer cells exposed to diindolylmethane.
Topics: Apoptosis; Benzylamines; Calcium; Calcium Signaling; Chelating Agents; Cyclosporine; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Female; Humans; Indoles; Male; Prostatic Neoplasms; Sulfonamides; Thapsigargin; Uterine Cervical Neoplasms | 2006 |
Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aryl Hydrocarbon Hydroxylases; Calcium; Cell Line, Transformed; Cyclosporine; Cytochrome P-450 CYP2C9; Cytosol; Diclofenac; Dose-Response Relationship, Drug; Drug Antagonism; Egtazic Acid; Hepatocytes; Humans; Membrane Potentials; Mitochondria, Liver; Mitochondrial Membranes; Oxidation-Reduction; Permeability; Sulfaphenazole; Superoxides; Uncoupling Agents | 2006 |
Mitochondrial Ca2+ cycle mediated by the palmitate-activated cyclosporin A-insensitive pore.
Topics: Animals; Calcium; Calcium Channels; Cyclosporine; Egtazic Acid; Fatty Acids; In Vitro Techniques; Lanthanum; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membranes; Mitochondrial Proteins; Mitochondrial Swelling; Palmitic Acid; Phospholipase A2 Inhibitors; Rats; Rats, Wistar; Ruthenium Red | 2007 |
Nuclear factor of activated T cells and early growth response-1 cooperate to mediate tissue factor gene induction by vascular endothelial growth factor in endothelial cells.
Topics: Calcineurin; Calcineurin Inhibitors; Calcium; Cells, Cultured; Chelating Agents; Cyclosporine; DNA-Binding Proteins; Early Growth Response Protein 1; Egtazic Acid; Endothelial Cells; Epidermal Growth Factor; Humans; Intracellular Signaling Peptides and Proteins; Muscle Proteins; NFATC Transcription Factors; Promoter Regions, Genetic; Repressor Proteins; RNA, Messenger; Signal Transduction; Thromboplastin; Time Factors; Transcription, Genetic; Transfection; Up-Regulation; Vascular Endothelial Growth Factor A | 2007 |
Role of calcium and cyclophilin D in the regulation of mitochondrial permeabilization induced by glutathione depletion.
Topics: Acetylcysteine; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Chelating Agents; Cyclophilins; Cyclosporine; Cytosol; Egtazic Acid; Flow Cytometry; Free Radical Scavengers; Glutathione; Humans; Membrane Potential, Mitochondrial; Mitochondria; Organophosphorus Compounds; Peptidyl-Prolyl Isomerase F; Permeability; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Ubiquinone | 2007 |
Effect of magnesium on calcium-induced depolarisation of mitochondrial transmembrane potential.
Topics: Adenosine Diphosphate; Animals; Calcimycin; Calcium; Cyclosporine; Egtazic Acid; Magnesium; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Rats; Rats, Wistar; Ruthenium Red | 2008 |
The inositol 1,4,5-trisphosphate receptor is required to signal autophagic cell death.
Topics: Animals; Apoptosis; Autophagy; Cyclosporine; Dictyostelium; Egtazic Acid; Genes, Protozoan; Inositol 1,4,5-Trisphosphate Receptors; Models, Biological; Mutagenesis, Insertional; Mutation; Necrosis; Protozoan Proteins; Signal Transduction; Thapsigargin | 2008 |
Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling.
Topics: Active Transport, Cell Nucleus; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Calcineurin; Calcineurin Inhibitors; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Cyclosporine; Disease Models, Animal; DNA-Binding Proteins; Egtazic Acid; Enzyme Activation; Humans; Ionophores; Mice; Neuroblastoma; NFATC Transcription Factors; Promoter Regions, Genetic; Up-Regulation | 2008 |
Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Calcium; Cell Line; Chelating Agents; Cyclophilins; Cyclosporine; Cytoprotection; Diclofenac; Egtazic Acid; Hepatocytes; Humans; MAP Kinase Kinase Kinase 5; Mitochondria, Liver; Mitochondrial Membranes; Mitochondrial Proteins; Permeability; RNA, Small Interfering; Thioredoxins | 2008 |
Improvement in the in vitro maturation rate of porcine oocytes vitrified at the germinal vesicle stage by treatment with a mitochondrial permeability transition inhibitor.
Topics: Amino Acid Chloromethyl Ketones; Animals; Cell Survival; Cells, Cultured; Chelating Agents; Cryopreservation; Cryoprotective Agents; Cyclosporine; Cysteine Proteinase Inhibitors; Egtazic Acid; Enzyme Inhibitors; Female; Metaphase; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oocytes; Ruthenium Red; Swine | 2008 |
Phosphatidylinositol-linked novel D(1) dopamine receptor facilitates long-term depression in rat hippocampal CA1 synapses.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Chelating Agents; Cyclosporine; Dopamine Agonists; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Type C Phospholipases | 2009 |
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway.
Topics: Calcineurin; Calcineurin Inhibitors; Cell Line, Tumor; Cyclosporine; Decidua; Egtazic Acid; Endometrium; Enzyme-Linked Immunosorbent Assay; Female; Flavonoids; Gene Expression Regulation; Humans; Immunohistochemistry; Interleukin-11; NFATC Transcription Factors; Peptides, Cyclic; Pregnancy; Pregnancy Trimester, First; Receptors, G-Protein-Coupled; Vascular Endothelial Growth Factor, Endocrine-Gland-Derived | 2010 |
Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Cell Differentiation; Chelating Agents; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cyclosporine; Egtazic Acid; Mice; Mutation; NFATC Transcription Factors; Osteoblasts; Parathyroid Hormone; Promoter Regions, Genetic; Tacrolimus; Transcription Factor AP-1; Transcription, Genetic; Transfection | 2010 |
Inhibition of calcineurin phosphatase promotes exocytosis of renin from juxtaglomerular cells.
Topics: Animals; Calcineurin; Calcium; Calmodulin; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Electric Capacitance; Exocytosis; Immunosuppressive Agents; Juxtaglomerular Apparatus; Male; Mice; Patch-Clamp Techniques; Phosphoric Monoester Hydrolases; Protein Isoforms; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sulfonamides | 2010 |
The Ca2+-dependent phosphatase calcineurin controls the formation of the Carma1-Bcl10-Malt1 complex during T cell receptor-induced NF-kappaB activation.
Topics: Adaptor Proteins, Signal Transducing; Animals; B-Cell CLL-Lymphoma 10 Protein; Calcineurin; Calcium; CARD Signaling Adaptor Proteins; Caspases; Cyclosporine; Egtazic Acid; Guanylate Cyclase; HEK293 Cells; Humans; Immunosuppressive Agents; Jurkat Cells; Mice; Mice, Inbred Strains; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; NF-kappa B; Phosphorylation; RNA, Small Interfering; Signal Transduction; T-Lymphocytes; Tacrolimus | 2011 |
Alteration in mitochondrial thiol enhances calcium ion dependent membrane permeability transition and dysfunction in vitro: a cross-talk between mtThiol, Ca(2+), and ROS.
Topics: Animals; Apoptosis Regulatory Proteins; Calcium; Cell Membrane Permeability; Cyclosporine; Egtazic Acid; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfhydryl Compounds | 2011 |
Measurements of threshold of mitochondrial permeability transition pore opening in intact and permeabilized cells by flash photolysis of caged calcium.
Topics: Animals; Calcium; Cyclosporine; Egtazic Acid; Ion Channel Gating; Membrane Potential, Mitochondrial; Mice; Microscopy, Confocal; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Permeability; Photolysis; Rhodamines; Spectrometry, Fluorescence | 2011 |
Reactive oxygen species and permeability transition pore in rat liver and kidney mitoplasts.
Topics: Adenosine Diphosphate; Animals; Catalase; Chelating Agents; Cyclosporine; Egtazic Acid; Enzyme Inhibitors; Female; Hydrogen Peroxide; Kidney; Liver; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Organ Specificity; Oxidation-Reduction; Rats; Rats, Wistar; tert-Butylhydroperoxide | 2011 |
Rapid homeostatic plasticity of intrinsic excitability in a central pattern generator network stabilizes functional neural network output.
Topics: 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Brachyura; Chelating Agents; Cyclosporine; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Female; Ganglia, Invertebrate; Homeostasis; Male; Motor Neurons; Nerve Net; Neuronal Plasticity; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; RNA, Messenger; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2012 |
Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation.
Topics: Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Transformed; Chelating Agents; Cyclosporine; Diglycerides; Egtazic Acid; Fibroblasts; Group IV Phospholipases A2; Isoenzymes; L-Lactate Dehydrogenase; Mice; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Phospholipase A2 Inhibitors; Pyrrolidines; Thapsigargin | 2014 |
Ischemia-induced endothelial cell swelling and mitochondrial dysfunction are attenuated by cinnamtannin D1, green tea extract, and resveratrol in vitro.
Topics: Animals; Antioxidants; Brain Ischemia; Calcium; Cell Line; Chemokine CCL2; Cyclosporine; Egtazic Acid; Endothelial Cells; Glucose; Hypoxia; Interleukin-6; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Plant Extracts; Polyphenols; Proanthocyanidins; Reactive Oxygen Species; Resveratrol; Stilbenes; Tea; Tumor Necrosis Factor-alpha | 2015 |
Inhibition of ATP synthesis by fenbufen and its conjugated metabolites in rat liver mitochondria.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Egtazic Acid; Glutathione; Male; Mitochondria, Liver; NADP; Oxidative Phosphorylation; Phenylbutyrates; Rats, Sprague-Dawley; Rotenone | 2016 |
T Cells of Infants Are Mature, but Hyporeactive Due to Limited Ca2+ Influx.
Topics: Adolescent; Adult; Calcium; CD28 Antigens; CD4-Positive T-Lymphocytes; Cell Nucleus; Cells, Cultured; Child; Child, Preschool; Cyclosporine; Egtazic Acid; Fetal Blood; Humans; Infant; Infant, Newborn; Interleukin-2; Lymphocyte Activation; Middle Aged; NFATC Transcription Factors; Platelet Endothelial Cell Adhesion Molecule-1; Signal Transduction; Tumor Necrosis Factor-alpha; Young Adult | 2016 |
Calcium-mediated oxidative stress: a common mechanism in tight junction disruption by different types of cellular stress.
Topics: Animals; Caco-2 Cells; Calcium; Calcium Channels; Calcium Channels, L-Type; Chelating Agents; Colon; Corticosterone; CSK Tyrosine-Protein Kinase; Cyclosporine; Dextran Sulfate; Egtazic Acid; Gene Expression Regulation; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Osmotic Pressure; Oxidative Stress; Reactive Oxygen Species; src-Family Kinases; Stress, Mechanical; Stress, Psychological; Tight Junctions; TRPV Cation Channels | 2017 |