egtazic acid has been researched along with arachidonic acid in 127 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (14.96) | 18.7374 |
| 1990's | 78 (61.42) | 18.2507 |
| 2000's | 26 (20.47) | 29.6817 |
| 2010's | 4 (3.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ditschuneit, H; Preclik, G; Stange, EF | 1 |
| Jordan, P; Kaszkin, M; Kinzel, V; Schiess, K; Seidler, L | 1 |
| Schatz-Munding, M; Ullrich, V | 1 |
| Bahler, C; Garcia, JG; Natarajan, V; Stasek, JE | 1 |
| Marshall, LA; McCarte-Roshak, A | 1 |
| Mattera, R; Xing, M | 1 |
| Debbaghi, A; Hidi, R; Touqui, L; Vargaftig, BB | 1 |
| Brown, EJ; Lefkowith, JB; Lennartz, MR; Morrison, AR; Rogers, M | 1 |
| Dominguez, J; Garcia, JG; Natarajan, V; Patterson, CE; Stasek, J | 1 |
| Gross, R; Ramanadham, S; Turk, J | 1 |
| Balsinde, J; Fernández, B | 1 |
| Barchowsky, A; Buckley, BJ; Dolor, RJ; Whorton, AR | 1 |
| Crumpton, MJ; Edwards, HC | 1 |
| Cybulsky, AV | 1 |
| Samochocki, M; Strosznajder, J | 2 |
| Holst, E; Sundler, R; Svensson, U | 1 |
| Rink, TJ; Sage, SO; Vindlacheruvu, RR | 1 |
| Jope, RS; Li, XH; Song, L | 1 |
| Channon, JY; Leslie, CC | 1 |
| MacQuarrie, RA; Navidi, M; Sun, GY | 1 |
| Vanderhoek, JY; Vonakis, BM | 1 |
| Dani, GM; Englen, MD; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Taylor, SM | 1 |
| Alonso, MT; Garcia-Sancho, J; Sanchez, A | 1 |
| Damron, DS; Dorman, RV | 1 |
| Hatzelmann, A; Haurand, M; Ullrich, V | 1 |
| Chakraborti, S; Gurtner, GH; Michael, JR | 1 |
| Chap, H; Fauvel, J; Hullin, F; Ragab-Thomas, JM; Raynal, P | 1 |
| Borgeat, P; Caon, AC; McColl, SR; Naccache, PH | 1 |
| Barbour, SE; Imagawa, DK; Morgan, BP; Ramm, LE; Shin, HS; Wright, TM | 1 |
| Bender, JG; Van Epps, DE | 1 |
| Dunlop, ME; Malaisse, WJ | 1 |
| Chovaniec, ME; Cohen, HJ; Takahashi, K; Whitin, JC | 1 |
| Morimoto, YM; Nobori, K; Sato, E; Takahashi, R; Utsumi, K | 1 |
| Malmgren, R | 1 |
| Crost, S; Martin, MK; Palmer, JW | 1 |
| Fujimoto, Y; Fujita, T; Hase, Y; Nishioka, K; Sado, K | 1 |
| Schimmel, RJ | 1 |
| Kinsella, JE; Lokesh, BR | 1 |
| Khan, SN; Lane, PA; Smith, AD | 1 |
| Baker, RR; Chang, HY | 1 |
| Laychock, SG | 1 |
| Fujimoto, Y; Fujita, T; Kagen, C; Ueno, T; Uno, H | 1 |
| Bowman, BJ; Iden, SS; Smith, RJ | 1 |
| Hatanaka, T; Kambayashi, J; Kosaki, G; Murata, A; Nakamura, K; Nishibe, S; Ogawa, M | 1 |
| Grinstein, S; Kapus, A; Romanek, R | 1 |
| Grinnell, F; He, Y | 1 |
| Garcia, M; Ito, S; Nakanishi, S; Sakamoto, K; Shigekawa, M | 1 |
| Fujimoto, R; Hata, F; Kubo, T; Nagao, T; Nishio, H; Takeuchi, T | 1 |
| Cook, NE; Tribble, DL; van den Berg, JJ | 1 |
| Aarab, L; Chabardès, D; de Rouffignac, C; Firsov, D; Mandon, B; Siaume-Perez, S | 1 |
| Gross, RW; Rudolph, AE; Sommers, CD; Wang, J; Wolf, MJ | 1 |
| Giovannardi, S; Lazrak, A; Peracchia, C; Peres, A | 1 |
| Käfer, A; Krug, HF | 1 |
| Belton, CM; Fatherazi, S; Izutsu, KT; Wellner, RB | 1 |
| Gist, ID; Smallridge, RC | 1 |
| Kotoyori, J; Kozawa, O; Oiso, Y; Suzuki, A | 1 |
| Brooker, G; Mattie, M; Spiegel, S | 1 |
| Evangelista, V; Locati, M; Luini, W; Mantovani, A; Sozzani, S; Zhou, D | 1 |
| Borowitz, JL; Isom, GE; Rathinavelu, A; Yang, CW | 1 |
| Errasfa, M; Stern, A | 1 |
| de la Llosa-Hermier, MP; Fernandez, C; Hermier, C; Martal, J | 1 |
| Boeynaems, JM; Braekman, JC; Broeders, F; Heilporn, S | 1 |
| Gross, RW; Han, X; Kruszka, KK; Ramanadham, S; Turk, J | 1 |
| Foley, PL; Kassell, NF; Lee, KS; Takenaka, K | 1 |
| Conigrave, AD; Jiang, L; Packham, DE | 1 |
| Aoki, Y; Hirano, D; Kodama, H; Nakamura, M; Ogasawara, H; Sakanaka, C; Shimizu, T; Waga, I | 1 |
| Alessandro, R; Brilley, E; Felder, CC; Jacobs, W; Kohn, EC; Probst, J | 1 |
| Bonventre, JV; Sapirstein, A; Spech, RA; Witzgall, R | 1 |
| Shuttleworth, TJ | 1 |
| Donowitz, M; Flick, J; Levine, SA; Madara, JL; Sharp, GW; Tai, YH | 1 |
| Brock, T; Marshall, T; Peters-Golden, M; Song, K | 1 |
| Hata, F; Nishio, H; Takeuchi, T; Yagasaki, O | 1 |
| Alkon, DL; Lester, DS; Schachter, JB | 1 |
| Castro, E; Herrero, I; Miras-Portugal, MT; Sánchez-Prieto, J | 1 |
| Gross, RW; Turk, J; Wang, J; Wolf, MJ | 1 |
| Chung, HC; Fleming, N | 1 |
| Horimoto, N; Nabekura, J; Ogawa, T | 1 |
| Strosznajder, J | 1 |
| Canessa, M; Fathallah, H; Giraud, F; Romero, JR; Sauvage, M | 1 |
| Dorman, RV; Freeman, EJ; Ruehr, ML | 1 |
| Boland, R; de Boland, AR; Facchinetti, MM | 1 |
| Kanayasu-Toyoda, T; Morita, I; Murota, S | 1 |
| Basavappa, S; Ellory, JC; Hoffmann, EK; Jørgensen, NK; Pedersen, SF | 1 |
| Dai, J; Liu, SY; Panagia, V; Tappia, PS; Williams, SA | 1 |
| Bohrer, A; Hsu, FF; Ma, Z; Nowatzke, W; Ramanadham, S; Turk, J | 1 |
| Kashiwagi, K; Saito, N; Sakai, N; Shirai, Y; Yagi, K | 1 |
| Daniel, WG; Garlichs, CD; Mügge, A; Zhang, H | 1 |
| Berliner, JA; Frankel, M; Goldhaber, JI; Honda, HM; Leitinger, N; Nadler, JL; Natarajan, R; Weiss, JN | 1 |
| Leoncini, G; Signorello, MG | 1 |
| Chavkin, C; Cyr, C; Rogalski, SL | 1 |
| Goracci, G; Gresele, P; Macchioni, L; Nardicchi, V; Nenci, GG; Nucciarelli, F; Porcellati, S | 1 |
| Kovacs, RJ; Leaver, AH; Rizzo, MT; Yu, WM | 1 |
| Gijón, MA; Kaiser, AL; Leslie, CC; Spencer, DM | 1 |
| Akiba, S; Hayama, M; Kume, K; Mizunaga, S; Sato, T | 1 |
| Bymaster, FP; Calligaro, DO; Falcone, JF | 1 |
| Chang, X; Chen, EC; Javors, MA; King, TS; Norris, C; Schenken, RS | 1 |
| Ganey, PE; Olivero, J; Ruehle, K; Tithof, PK | 1 |
| Gawdi, G; Misra, UK; Pizzo, SV | 1 |
| Fujishiro, T; Fukuyama, K; Ikeda, M; Ito, K; Shiraishi, M | 1 |
| Schulz, I; Sternfeld, L; Thévenod, F | 1 |
| Honeyman, T; Ignotz, RA | 1 |
| Dominguez, Z; Dubois, M; Lagarde, M; Macovschi, O; Merhi-Soussi, F; Prigent, AF; Savany, A | 1 |
| Awata, H; Handlogten, ME; Huang, C; Miller, RT; Shiraishi, N | 1 |
| Hirata, M; Nagaoka, I; Niyonsaba, F; Ogawa, H; Someya, A | 1 |
| Mori, A; Murayama, T; Nomura, Y; Yasuda, Y | 1 |
| Chang, LC; Wang, JP | 1 |
| Boetticher, E; Leff, AR; Muñoz, NM; Sano, A; Sano, H; Zhu, X | 1 |
| Fasia, L; Karava, V; Siafaka-Kapadai, A | 1 |
| Chen, WY; Fang, X; Mao, LZ; Roldan, ER; Shi, QX; Yu, SQ; Yuan, YY | 1 |
| Bari, M; Battista, N; Cogoli, A; Finazzi-Agrò, A; Galleri, G; Maccarrone, M; Meloni, M; Pippia, P | 1 |
| Mauban, JR; Wier, WG | 1 |
| Chen, CC; Hsu, MF; Kuan, YH; Lu, MC; Tsao, LT; Wang, JP | 1 |
| Barrett, NE; Coffey, MJ; Coles, B; Gibbins, JM; Jarvis, GE; O'Donnell, VB; Wylie, OR | 1 |
| MacVicar, BA; Mulligan, SJ | 1 |
| Brant, K; Caruso, RL | 1 |
| Choi, HJ; Ha, KS; Han, JA; Kim, WJ; Kim, YM; Yi, SJ; Yoo, JO | 1 |
| Borgeat, P; Flamand, N; Lefebvre, J; Picard, S; Surette, ME | 1 |
| Belysheva, TS; Dukhanin, AS; Ogurtsov, SI; Teplyuk, NP | 1 |
| Blaesius, D; Lusche, DF; Schaloske, RH; Schlatterer, C | 1 |
| Dong, B; Matsumura, F | 1 |
| Gawler, D; Hastings, AD; Herbert, SP; Walker, JH | 1 |
| Armando, A; Dennis, EA; Grkovich, A; Quehenberger, O | 1 |
| Bibus, D; Khanna, S; Kotha, SR; Parinandi, NL; Rink, C; Roy, S; Sen, CK | 1 |
| Tseng, CL; Wei, JW | 1 |
| Bonventre, JV; Cravatt, BF; Ewing, H; Gelb, MH; Ghosh, M; Hsu, KL; Lee, H; Leslie, CC; Yun, B | 1 |
| Hart, J; Kotha, SR; Lawson, C; Magalang, UJ; Malireddy, S; Marsh, CB; Parinandi, NL; Patel, RB; Romberger, D; Steinhour, E; Wewers, MD; Wilkins, JR; Zhao, L | 1 |
127 other study(ies) available for egtazic acid and arachidonic acid
| Article | Year |
|---|---|
Activation of PGE2-secretion from gastric mucosa by a type I phospholipase C is mediated by a direct release of arachidonic acid.
Topics: Animals; Arachidonic Acid; Calcium; Calmodulin; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Gastric Mucosa; Male; Organ Culture Techniques; Phospholipases; Rabbits; Radioimmunoassay; Sulfonamides; Type C Phospholipases | 1992 |
Mobilization of diacylglycerol in intact HeLa cells by exogenous phospholipase C from Cl. perfringens is accompanied by release of fatty acids including arachidonic acid.
Topics: Arachidonic Acid; Chromatography, Thin Layer; Clostridium perfringens; Diglycerides; Egtazic Acid; Enzyme Activation; Fatty Acids; Fluocinolone Acetonide; HeLa Cells; Humans; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phospholipases A; Phospholipases A2; Phosphoric Diester Hydrolases; Quinacrine; Type C Phospholipases | 1992 |
Regulation of leukotriene biosynthesis in human polymorphonuclear leukocytes.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Chromatography, High Pressure Liquid; Egtazic Acid; Fluorescent Dyes; Fura-2; Humans; Ionomycin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1992 |
Interleukin 1-stimulated prostacyclin synthesis in endothelium: lack of phospholipase C, phospholipase D, or protein kinase C involvement in early signal transduction.
Topics: Arachidonic Acid; Cells, Cultured; Cyclic AMP; Egtazic Acid; Endothelium, Vascular; Epoprostenol; Humans; Interleukin-1; Phospholipase D; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Demonstration of similar calcium dependencies by mammalian high and low molecular mass phospholipase A2.
Topics: Animals; Arachidonic Acid; Buffers; Calcium; Cattle; Cricetinae; Egtazic Acid; Escherichia coli; Extracellular Space; Humans; Isoenzymes; Kinetics; Molecular Weight; Phospholipases A; Phospholipases A2; Tritium | 1992 |
Phosphorylation-dependent regulation of phospholipase A2 by G-proteins and Ca2+ in HL60 granulocytes.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Alkaloids; Arachidonic Acid; Calcium; Egtazic Acid; Enzyme Activation; Granulocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Homeostasis; Humans; Isoflurophate; Kinetics; Leukemia, Promyelocytic, Acute; Models, Biological; Pertussis Toxin; Phosphorylation; Protein Kinase C; Ribonucleotides; Staurosporine; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Inhibition of phospholipase A2 activity in guinea pig eosinophils by human recombinant IL-1 beta.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Egtazic Acid; Eosinophils; Guinea Pigs; In Vitro Techniques; Interleukin-1; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Recombinant Proteins | 1992 |
Phospholipase activation during monocyte adherence and spreading.
Topics: Acetophenones; Arachidonic Acid; Calcium; Cell Adhesion; Cells, Cultured; Egtazic Acid; Enzyme Activation; Humans; Monocytes; Phospholipases; Tetradecanoylphorbol Acetate | 1992 |
Role of protein kinase C in the regulation of prostaglandin synthesis in human endothelium.
Topics: Aequorin; Affinity Labels; Alkaloids; Arachidonic Acid; Calcimycin; Calcium; Cations, Divalent; Down-Regulation; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Humans; Inositol Phosphates; Luminescent Measurements; Protein Kinase C; Radioimmunoassay; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Arachidonic acid induces an increase in the cytosolic calcium concentration in single pancreatic islet beta cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Calcium; Cytosol; Egtazic Acid; Flow Cytometry; Fluorescent Dyes; Fura-2; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Nifedipine; Potassium Chloride | 1992 |
Receptor-mediated activation of arachidonic acid release in mouse peritoneal macrophages is linked to extracellular calcium influx.
Topics: Animals; Arachidonic Acid; Calcium; Cells, Cultured; Egtazic Acid; Kinetics; Macrophages; Mice; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Receptors, Cell Surface; Verapamil; Zymosan | 1991 |
Regulation of arachidonic acid release in vascular endothelium. Ca(2+)-dependent and -independent pathways.
Topics: Alkaloids; Animals; Aorta; Arachidonic Acid; Bradykinin; Calcium; Cell Survival; Cells, Cultured; Chelating Agents; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; GTP-Binding Proteins; Lysophospholipids; Protein Kinase C; Sodium Fluoride; Staurosporine; Swine; Tetradecanoylphorbol Acetate | 1991 |
Ca(2+)-dependent phospholipid and arachidonic acid binding by the placental annexins VI and IV.
Topics: Annexin A6; Annexins; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium-Binding Proteins; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Female; Humans; Phospholipases A; Phospholipases A2; Phospholipids; Placenta; Pregnancy; Pregnancy Proteins; Substrate Specificity | 1991 |
Release of arachidonic acid by complement C5b-9 complex in glomerular epithelial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Complement Membrane Attack Complex; Cyclohexanones; Diglycerides; Edetic Acid; Egtazic Acid; Epithelium; Fatty Acids, Nonesterified; Kidney Glomerulus; Kinetics; Lipase; Lipoprotein Lipase; Phospholipases A; Phospholipases A2; Phospholipids; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1991 |
Ca(2+)-independent, Ca(2+)-dependent, and carbachol-mediated arachidonic acid release from rat brain cortex membrane.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carbachol; Cerebral Cortex; Egtazic Acid; Membranes; Osmolar Concentration; Rats; Synaptosomes | 1991 |
Protein-kinase-C-independent activation of arachidonate release and prostaglandin E2 formation in macrophages interacting with certain bacteria.
Topics: Animals; Arachidonic Acid; Bacterial Physiological Phenomena; Calcimycin; Calcium; Dinoprostone; Egtazic Acid; Female; Fusobacterium; Gardnerella vaginalis; Macrophages; Mice; Peptostreptococcus; Peritoneal Cavity; Propionibacterium acnes; Protein Kinase C | 1991 |
Lack of evidence for a role for the lipoxygenase pathway in increases in cytosolic calcium evoked by ADP and arachidonic acid in human platelets.
Topics: Adenosine Diphosphate; Affinity Labels; Arachidonic Acid; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Cytosol; Egtazic Acid; Fura-2; Humans; Lipoxygenase; Lipoxygenase Inhibitors | 1991 |
Modulation of phosphoinositide metabolism in rat brain slices by excitatory amino acids, arachidonic acid, and GABA.
Topics: Amino Acids; Animals; Arachidonic Acid; Arachidonic Acids; Brain; Calcium; Carbachol; Egtazic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hydrolysis; Kinetics; Male; Manganese; Norepinephrine; Oxadiazoles; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Quisqualic Acid; Rats; Rats, Inbred Strains; Verapamil | 1990 |
A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Fractionation; Cell Line; Cell Membrane; Egtazic Acid; Enzyme Activation; Liposomes; Macrophages; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipases; Phospholipases A; Phospholipases A2 | 1990 |
Metabolism of phosphatidylinositol in plasma membranes and synaptosomes of rat cerebral cortex: a comparison between endogenous vs exogenous substrate pools.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carbon Radioisotopes; Cell Membrane; Cerebral Cortex; Chromatography, Gas; Deoxycholic Acid; Diglycerides; Egtazic Acid; Fatty Acids; Hydrolysis; Lysophospholipids; Phosphatidylcholines; Phosphatidylinositols; Phospholipases A; Phospholipids; Rats; Rats, Inbred Strains; Synaptosomes; Type C Phospholipases | 1990 |
A calcium-independent 5-lipoxygenase system in mast/basophil PT-18 cells.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Basophils; Calcium; Calcium Channel Blockers; Cell Line; Cytosol; Egtazic Acid; Gallic Acid; Hydroxyeicosatetraenoic Acids; Ionomycin; Mast Cells; Mice | 1990 |
Influence of extracellular calcium on the metabolism of arachidonic acid in alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cattle; Egtazic Acid; Indomethacin; Macrophages; Phospholipases A; Phospholipases A2; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Arachidonic acid-induced calcium influx in human platelets. Comparison with the effect of thrombin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Biological Transport; Blood Platelets; Calcium; Carcinoma, Ehrlich Tumor; Egtazic Acid; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Fluoresceins; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; Kinetics; Manganese; Masoprocol; Mice; Neutrophils; Prostaglandin Endoperoxides, Synthetic; Rats; Spectrometry, Fluorescence; Structure-Activity Relationship; T-Lymphocytes; Thrombin | 1990 |
Regulation of arachidonic acid release by enzyme(s) of rat brain cortex.
Topics: Arachidonic Acid; Arachidonic Acids; Calcium Chloride; Carbon Radioisotopes; Cerebral Cortex; Egtazic Acid; Kinetics; Neomycin; Phospholipases A; Phospholipases A2; Phospholipids; Quinacrine; Type C Phospholipases | 1990 |
Calcium-dependent phospholipid catabolism and arachidonic acid mobilization in cerebral minces.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Brain Injuries; Calcium; Egtazic Acid; Kinetics; Male; Phospholipids; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Tritium; Verapamil | 1990 |
Involvement of calcium in the thimerosal-stimulated formation of leukotriene by fMLP in human polymorphonuclear leukocytes.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcium; Drug Synergism; Egtazic Acid; Ethylmercury Compounds; Humans; Leukotriene B4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Thimerosal | 1990 |
Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Kinetics; Peroxides; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin D2; Pulmonary Artery; tert-Butylhydroperoxide; Thromboxane B2; Vitamin E | 1989 |
Effect of dexamethasone on prostaglandin synthesis and on lipocortin status in human endothelial cells. Inhibition of prostaglandin I2 synthesis occurring without alteration of arachidonic acid liberation and of lipocortin synthesis.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Annexins; Arachidonic Acid; Arachidonic Acids; Calcium-Binding Proteins; Dexamethasone; Dinoprost; Dinoprostone; Egtazic Acid; Endothelium, Vascular; Epoprostenol; Glycoproteins; Humans; Hydroxyeicosatetraenoic Acids; Immunoassay; Kinetics; Phospholipases A; Phospholipases A2; Phospholipids; Thrombin | 1989 |
Arachidonic acid-induced mobilization of calcium in human neutrophils: evidence for a multicomponent mechanism of action.
Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cholera Toxin; Egtazic Acid; Humans; In Vitro Techniques; Leukotriene B4; Masoprocol; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Virulence Factors, Bordetella | 1989 |
Role of complement C9 and calcium in the generation of arachidonic acid and its metabolites from rat polymorphonuclear leukocytes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Complement C9; Complement Membrane Attack Complex; Complement System Proteins; Egtazic Acid; Kinetics; Leukotriene B4; Male; Neutrophils; Rats; Rats, Inbred Strains | 1987 |
Stimulus interactions in release of superoxide anion (O2-) from human neutrophils. Further evidence for multiple pathways of activation.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Complement C5; Complement C5a; Concanavalin A; Drug Synergism; Egtazic Acid; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Phosphoinositide phosphorylation and hydrolysis in pancreatic islet cell membrane.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Calcium; Carbachol; Carbon Radioisotopes; Cell Membrane; Egtazic Acid; Hydrolysis; In Vitro Techniques; Islets of Langerhans; Membrane Lipids; Phosphatidylinositols; Phosphorus Radioisotopes; Phosphorylation; Rats; Verapamil | 1986 |
Activation of human granulocytes by arachidonic acid: its use and limitations for investigating granulocyte functions.
Topics: Arachidonic Acid; Arachidonic Acids; Concanavalin A; Cytoplasm; Egtazic Acid; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Muramidase; Neutrophils; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Effect of calcium ion on fatty acid-induced generation of superoxide in guinea pig neutrophils.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Chlorpromazine; Egtazic Acid; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Guinea Pigs; In Vitro Techniques; Kinetics; Liposomes; Male; Neutrophils; Structure-Activity Relationship; Superoxides | 1986 |
ATP-secretion occurs as an initial response in collagen induced platelet activation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Edetic Acid; Egtazic Acid; Humans; Kinetics; Platelet Aggregation; Theophylline; Verapamil; Yohimbine | 1986 |
Hormonal effects on mitochondrial respiration: potential role of endogenous lipolytic activities.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Egtazic Acid; Kinetics; Lipolysis; Male; Mitochondria, Heart; Myocardium; Oxygen Consumption; Parathyroid Glands; Rats; Rats, Inbred Strains; Sarcolemma; Stearic Acids; Thyroidectomy | 1987 |
Triacylglycerol lipase-mediated release of arachidonic acid for renal medullary prostaglandin synthesis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Egtazic Acid; In Vitro Techniques; Kidney Medulla; Lipase; Prostaglandins E; Rabbits; Triglycerides | 1988 |
The alpha 1-adrenergic transduction system in hamster brown adipocytes. Release of arachidonic acid accompanies activation of phospholipase C.
Topics: Adipose Tissue, Brown; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Colforsin; Cricetinae; Cyclohexanones; Egtazic Acid; Enzyme Activation; In Vitro Techniques; Inositol Phosphates; Insulin; Isoproterenol; Lipid Metabolism; Male; Phenylephrine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Intracellular calcium does not appear to be essential for arachidonic acid release from stimulated macrophages as shown by studies with Quin-2.
Topics: Aminoquinolines; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Egtazic Acid; In Vitro Techniques; Lipids; Macrophage Activation; Macrophages; Male; Mice; Tetradecanoylphorbol Acetate; Zymosan | 1985 |
Desaggregation of PAF-acether-aggregated platelets by verapamil and TMB-8 with reversal of phosphorylation of 40K and 20K proteins.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium Channel Blockers; Egtazic Acid; Gallic Acid; In Vitro Techniques; Lanthanum; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Proteins; Rabbits; Serotonin; Verapamil | 1985 |
The CMP-stimulated production of diacylglycerol and CDPdiacylglycerol in neuronal nuclei labelled with radioactive arachidonate.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Nucleus; Cerebral Cortex; Cytidine Diphosphate Diglycerides; Cytidine Monophosphate; Cytosine Nucleotides; Diglycerides; Egtazic Acid; Glycerides; Kinetics; Neurons; Nucleoside Diphosphate Sugars; Phospholipids; Rabbits; Tritium | 1985 |
Effects of hydroxyeicosatetraenoic acids on fatty acid esterification in phospholipids and insulin secretion in pancreatic islets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcium; Egtazic Acid; Fatty Acids; Glucose; Hydroxyeicosatetraenoic Acids; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase; Male; Phospholipids; Rats; Rats, Inbred Strains; SRS-A | 1985 |
Effect of diarachidonin on prostaglandin E2 synthesis in rabbit kidney medulla slices.
Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Diglycerides; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Glycerides; In Vitro Techniques; Kidney Medulla; Male; Phosphatidic Acids; Prostaglandins E; Quinacrine; Rabbits | 1985 |
Activation of the human neutrophil secretory process with 5(S),12(R)-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid.
Topics: Arachidonic Acid; Arachidonic Acids; Cations, Divalent; Cytochalasin B; Cytoplasmic Granules; Deoxyglucose; Dose-Response Relationship, Drug; Egtazic Acid; Exocytosis; Gallic Acid; Humans; Leukotriene B4; Muramidase; Neutrophils; Peroxidase; Time Factors; Trifluoperazine | 1984 |
Inhibition of catecholamine release from isolated bovine adrenal medullary cells by various inhibitors: possible involvement of protease, calmodulin and arachidonic acid.
Topics: Acetylcholine; Adrenal Medulla; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium-Binding Proteins; Calmodulin; Catecholamines; Cattle; Egtazic Acid; L-Lactate Dehydrogenase; Protease Inhibitors; Time Factors | 1983 |
Arachidonic acid stimulates the plasma membrane H+ conductance of macrophages.
Topics: Animals; Arachidonic Acid; Cell Adhesion; Cell Membrane; Cells, Cultured; Egtazic Acid; Evoked Potentials; Fatty Acids, Nonesterified; Hydrogen; Ion Channels; Kinetics; Macrophages, Peritoneal; Magnesium Chloride; Membrane Potentials; Mice; Structure-Activity Relationship | 1994 |
Stress relaxation of fibroblasts activates a cyclic AMP signaling pathway.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Arachidonic Acid; Calcimycin; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Egtazic Acid; Extracellular Matrix; Fibroblasts; Humans; Indomethacin; Magnesium; Signal Transduction; Stress, Mechanical | 1994 |
Multiple mechanisms of arachidonic acid release in Chinese hamster ovary cells transfected with cDNA of substance P receptor.
Topics: Animals; Arachidonic Acid; Calcium; CHO Cells; Cricetinae; DNA, Complementary; Egtazic Acid; GTP-Binding Proteins; Inositol Phosphates; Pertussis Toxin; Receptors, Neurokinin-1; Substance P; Transfection; Virulence Factors, Bordetella | 1994 |
Ca(2+)-independent fusion of secretory granules with phospholipase A2-treated plasma membranes in vitro.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Albumins; Amylases; Animals; Arachidonic Acid; Benzoquinones; Calcium; Cell Membrane; Cytoplasmic Granules; Egtazic Acid; Exocytosis; Fatty Acids; Indomethacin; Lipoxygenase Inhibitors; Lysophosphatidylcholines; Male; Membrane Fusion; Microscopy, Electron; Parotid Gland; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Wistar | 1995 |
Reinvestigation of the antioxidant properties of conjugated linoleic acid.
Topics: Antioxidants; Arachidonic Acid; Butylated Hydroxytoluene; Egtazic Acid; Fatty Acids; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Linoleic Acid; Linoleic Acids; Liposomes; Oxidation-Reduction; Oxidative Stress; Phosphatidylcholines; Spectrophotometry; Vitamin E | 1995 |
Arachidonic acid inhibits hormone-stimulated cAMP accumulation in the medullary thick ascending limb of the rat kidney by a mechanism sensitive to pertussis toxin.
Topics: Animals; Arachidonic Acid; Arginine Vasopressin; Calcium; Cyclic AMP; Egtazic Acid; Fatty Acids; In Vitro Techniques; Kidney Medulla; Male; Pertussis Toxin; Protein Kinase C; Rats; Rats, Wistar; Virulence Factors, Bordetella | 1995 |
Nitric oxide activates the glucose-dependent mobilization of arachidonic acid in a macrophage-like cell line (RAW 264.7) that is largely mediated by calcium-independent phospholipase A2.
Topics: Animals; Arachidonic Acid; Calcium; Cell Line; Egtazic Acid; Kinetics; Lipopolysaccharides; Macrophages; Naphthalenes; Nitric Oxide; Nitroprusside; Phospholipases A; Phospholipases A2; Phospholipids; Pyrones; Second Messenger Systems; Tritium; Zymosan | 1995 |
Ca-mediated and independent effects of arachidonic acid on gap junctions and Ca-independent effects of oleic acid and halothane.
Topics: Animals; Arachidonic Acid; Biophysical Phenomena; Biophysics; Calcium; Egtazic Acid; Electric Conductivity; Gap Junctions; Halothane; Liver Neoplasms, Experimental; Oleic Acid; Oleic Acids; Rats; Tumor Cells, Cultured | 1994 |
Effects of organometals on cellular signaling. I. Influence of metabolic inhibitors on metal-induced arachidonic acid liberation.
Topics: Arachidonic Acid; Calcium; Cell Communication; Culture Media; Egtazic Acid; Homeostasis; Humans; Organometallic Compounds; Pertussis Toxin; Phospholipases A; Phospholipases A2; Quinacrine; Tumor Cells, Cultured; Verapamil; Virulence Factors, Bordetella | 1994 |
Hypotonically activated chloride current in HSG cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Actins; Arachidonic Acid; Calcium; Cell Line; Cell Membrane; Chloride Channels; Cytochalasin D; Cytoskeleton; Dose-Response Relationship, Drug; Egtazic Acid; Guanosine Triphosphate; Humans; Hypotonic Solutions; Nitrobenzoates; Patch-Clamp Techniques; Potassium Channels; Quinacrine; Submandibular Gland | 1994 |
P2-purinergic stimulation of iodide efflux in FRTL-5 rat thyroid cells involves parallel activation of PLC and PLA2.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cell Line; Egtazic Acid; Enzyme Activation; Estrenes; Iodides; Osmolar Concentration; Phospholipases A; Phospholipases A2; Protein Kinase C; Purines; Pyrrolidinones; Rats; Second Messenger Systems; Thyroid Gland; Type C Phospholipases | 1994 |
Prostaglandin E2 is a potential mediator of extracellular ATP action in osteoblast-like cells.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cell Line; Dinoprostone; DNA; Egtazic Acid; Indomethacin; Ion Transport; Mice; Osteoblasts | 1993 |
Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Bradykinin; Calcium; Calcium-Transporting ATPases; Cytosol; DNA; Egtazic Acid; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Kinetics; Lysophospholipids; Mice; Phorbol Esters; Second Messenger Systems; Sphingosine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1994 |
Rapid induction of arachidonic acid release by monocyte chemotactic protein-1 and related chemokines. Role of Ca2+ influx, synergism with platelet-activating factor and significance for chemotaxis.
Topics: Arachidonic Acid; Calcimycin; Calcium; Cell Line; Chemokine CCL2; Chemotactic Factors; Chemotaxis, Leukocyte; Cytokines; Egtazic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Recombinant Proteins; Structure-Activity Relationship; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1994 |
Activation of a calcium- and pH-dependent phospholipase A2 by cyanide in PC12 cells.
Topics: Animals; Arachidonic Acid; Calcium; Cell Survival; Egtazic Acid; Enzyme Activation; Hydrogen-Ion Concentration; PC12 Cells; Phospholipases A; Phospholipases A2; Potassium Cyanide; Rats | 1994 |
Inhibition of protein tyrosine phosphatase activity in HER14 cells by melittin and Ca2+ ionophore A23187.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Calcimycin; Calcium Chloride; Egtazic Acid; Epidermal Growth Factor; Humans; Indomethacin; Magnesium Chloride; Melitten; Mice; Phosphorylation; Protein Tyrosine Phosphatases; Transfection; Tumor Cells, Cultured | 1993 |
Potential role for arachidonic acid and eicosanoids in modulating progesterone secretion by ovine chorionic cells.
Topics: Allergens; Animals; Arachidonic Acid; Calcium; Calcium Channel Blockers; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Chorion; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Eicosanoids; Gallic Acid; Indomethacin; Masoprocol; Melitten; Phospholipases A; Phospholipases A2; Progesterone; Sheep | 1993 |
Enhancement of the endothelial production of prostacyclin by substituted derivatives of BAPTA-AM.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cattle; Cell Survival; Cells, Cultured; Choline; Cyclic AMP; Egtazic Acid; Endothelium, Vascular; Epoprostenol; Humans; Inositol Phosphates; Thromboxane B2 | 1993 |
Rat and human pancreatic islet cells contain a calcium ion independent phospholipase A2 activity selective for hydrolysis of arachidonate which is stimulated by adenosine triphosphate and is specifically localized to islet beta-cells.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cell Membrane; Cytosol; Egtazic Acid; Humans; Hydrolysis; Insulinoma; Islets of Langerhans; Male; Naphthalenes; Pancreatic Neoplasms; Phospholipases A; Phospholipases A2; Pyrones; Rats; Rats, Sprague-Dawley; Substrate Specificity; Tissue Distribution; Tumor Cells, Cultured | 1993 |
Oxyhemoglobin-induced cytotoxicity and arachidonic acid release in cultured bovine endothelial cells.
Topics: Animals; Arachidonic Acid; Cattle; Cell Size; Cells, Cultured; Cytotoxins; Disease Models, Animal; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Ischemic Attack, Transient; Oxyhemoglobins; Phospholipases A; Phospholipases A2; Superoxide Dismutase; Tritium; von Willebrand Factor | 1993 |
Arachidonate and other fatty acids mobilize Ca2+ ions and stimulate beta-glucuronidase release in a Ca(2+)-dependent fashion from undifferentiated HL-60 cells.
Topics: Arachidonic Acid; Calcium; Cations; Egtazic Acid; Fatty Acids; Fura-2; Glucuronidase; Humans; Leukemia, Promyelocytic, Acute; Tumor Cells, Cultured | 1995 |
Functional coupling of adenosine A2a receptor to inhibition of the mitogen-activated protein kinase cascade in Chinese hamster ovary cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Androstadienes; Animals; Arachidonic Acid; Base Sequence; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; DNA Primers; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Kinetics; Leukocytes; Molecular Sequence Data; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Recombinant Proteins; Signal Transduction; Thrombin; Transfection; Wortmannin | 1996 |
Identification and molecular characterization of a m5 muscarinic receptor in A2058 human melanoma cells. Coupling to inhibition of adenylyl cyclase and stimulation of phospholipase A2.
Topics: Adenylyl Cyclase Inhibitors; Arachidonic Acid; Base Sequence; Blotting, Southern; Calcium; Carbachol; Cell Adhesion; Cell Division; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; DNA Primers; Egtazic Acid; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Melanoma; Molecular Sequence Data; N-Methylscopolamine; Phospholipases A; Phospholipases A2; Polymerase Chain Reaction; Receptor, Muscarinic M5; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction; Time Factors; Tumor Cells, Cultured | 1996 |
Cytosolic phospholipase A2 (PLA2), but not secretory PLA2, potentiates hydrogen peroxide cytotoxicity in kidney epithelial cells.
Topics: Animals; Antioxidants; Arachidonic Acid; Calcimycin; Cell Line; Cell Survival; Chelating Agents; Cytosol; Drug Interactions; Egtazic Acid; Epithelial Cells; Epithelium; Glycine; Hydrogen Peroxide; Kidney; Mercuric Chloride; Phospholipases A; Phospholipases A2; Superoxide Dismutase; Swine; Vitamin K | 1996 |
Arachidonic acid activates the noncapacitative entry of Ca2+ during [Ca2+]i oscillations.
Topics: Alkaloids; Animals; Arachidonic Acid; Benzylisoquinolines; Calcium; Calcium Channel Blockers; Carbachol; Ducks; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Phospholipases A; Phospholipases A2; Proteins; Receptors, Muscarinic; Type C Phospholipases | 1996 |
Regulation of tight junction resistance in T84 monolayers by elevation in intracellular Ca2+: a protein kinase C effect.
Topics: Arachidonic Acid; Calcimycin; Calcium; Cell Membrane Permeability; Chelating Agents; Egtazic Acid; Humans; Ionophores; Mannitol; Phospholipases; Protein Kinase C; Quinacrine; Tetradecanoylphorbol Acetate; Tight Junctions; Tumor Cells, Cultured | 1996 |
Translocation of cytosolic phospholipase A2 to the nuclear envelope elicits topographically localized phospholipid hydrolysis.
Topics: Animals; Arachidonic Acid; Biological Transport, Active; Calcimycin; Calcium; Cells, Cultured; Chelating Agents; Cytosol; Egtazic Acid; Hydrolysis; Ionophores; Male; Nuclear Envelope; Phospholipases A; Phospholipases A2; Phospholipids; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley | 1996 |
Ca(2+)-independent fusion of synaptic vesicles with phospholipase A2-treated presynaptic membranes in vitro.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Albumins; Animals; Arachidonic Acid; Benzoquinones; Brain; Calcium; Egtazic Acid; Exocytosis; In Vitro Techniques; Indomethacin; Male; Membrane Fusion; Neurotransmitter Agents; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Wistar; Swine; Synaptic Membranes; Synaptic Vesicles | 1996 |
Synergistic activation of protein kinase C by arachidonic acid and diacylglycerols in vitro: generation of a stable membrane-bound, cofactor-independent state of protein kinase C activity.
Topics: Animals; Arachidonic Acid; Brain; Calcium; Chelating Agents; Diglycerides; Drug Synergism; Egtazic Acid; Enzyme Activation; Lipid Bilayers; Phosphatidylcholines; Phosphatidylserines; Protein Kinase C; Rats; Rats, Wistar | 1996 |
Two components of glutamate exocytosis differentially affected by presynaptic modulation.
Topics: Animals; Arachidonic Acid; Botulinum Toxins, Type A; Calcium; Cerebral Cortex; Chelating Agents; Egtazic Acid; Exocytosis; Glutamic Acid; Kinetics; Neuromuscular Agents; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Sensitivity and Specificity; Strontium; Synaptosomes; Type C Phospholipases | 1996 |
Depletion of intracellular calcium stores activates smooth muscle cell calcium-independent phospholipase A2. A novel mechanism underlying arachidonic acid mobilization.
Topics: Animals; Arachidonic Acid; Arginine Vasopressin; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Activation; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Rats | 1997 |
Muscarinic regulation of phospholipase D and its role in arachidonic acid release in rat submandibular acinar cells.
Topics: Animals; Arachidonic Acid; Calcium; Carbachol; Chelating Agents; Egtazic Acid; Enzyme Activation; In Vitro Techniques; Male; Muscarinic Agonists; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Type C Phospholipases | 1995 |
Arachidonic acid activation of potassium channels in rat visual cortex neurons.
Topics: 4-Aminopyridine; Animals; Apamin; Arachidonic Acid; Barium; Charybdotoxin; Docosahexaenoic Acids; Egtazic Acid; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Glyburide; In Vitro Techniques; Indomethacin; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Quinidine; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds; Visual Cortex | 1997 |
Regulation of phosphatidylethanolamine degradation by enzyme(s) of subcellular fractions from cerebral cortex.
Topics: Animals; Arachidonic Acid; Calcium; Cerebral Cortex; Diglycerides; Egtazic Acid; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hydrolysis; Neomycin; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Wistar; Subcellular Fractions; Synaptic Membranes; Type C Phospholipases | 1997 |
Effects of PKC alpha activation on Ca2+ pump and K(Ca) channel in deoxygenated sickle cells.
Topics: Anemia, Sickle Cell; Arachidonic Acid; Calcimycin; Calcium; Calcium-Transporting ATPases; Chromatography, DEAE-Cellulose; Cytosol; Diglycerides; Egtazic Acid; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Molecular Weight; Protein Kinase C; Protein Kinase C-alpha; Reference Values; Tetradecanoylphorbol Acetate | 1997 |
ANG II-induced translocation of cytosolic PLA2 to the nucleus in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arachidonic Acid; Calcium; Cell Nucleus; Cells, Cultured; Cytosol; Egtazic Acid; Estrenes; Imidazoles; Kinetics; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Pyridines; Pyrrolidinones; Rats | 1998 |
Calcitriol transmembrane signalling: regulation of rat muscle phospholipase D activity.
Topics: Animals; Arachidonic Acid; Calcitriol; Calcium; Calcium Channel Blockers; Cell Membrane; Chelating Agents; Diglycerides; Egtazic Acid; Ethanol; Glycerophospholipids; GTP-Binding Proteins; Muscle, Skeletal; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Arachidonic acid pretreatment enhances smooth muscle cell migration via increased Ca2+ influx.
Topics: Animals; Arachidonic Acid; Arteriosclerosis; Becaplermin; Calcium; Calcium Channel Blockers; Cattle; Cell Movement; Cells, Cultured; Culture Media; Egtazic Acid; Flavanones; Flavonoids; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular; Nifedipine; Phospholipids; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis | 1998 |
Swelling-induced arachidonic acid release via the 85-kDa cPLA2 in human neuroblastoma cells.
Topics: Arachidonic Acid; Arachidonic Acids; Chlorides; Cytosol; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; Hypotonic Solutions; Kinetics; Leukotriene D4; Molecular Weight; Neuroblastoma; Osmolar Concentration; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Pyrrolidinones; Taurine; Tumor Cells, Cultured | 1998 |
Phospholipase A2-mediated activation of phospholipase D in rat heart sarcolemma.
Topics: Animals; Antibodies, Monoclonal; Arachidonic Acid; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Melitten; Myocardium; Naphthalenes; Oleic Acid; Phosphatidylcholines; Phosphodiesterase Inhibitors; Phospholipase D; Phospholipases A; Phospholipases A2; Pyrones; Rats; Sarcolemma | 1998 |
Mass spectrometric evidence that agents that cause loss of Ca2+ from intracellular compartments induce hydrolysis of arachidonic acid from pancreatic islet membrane phospholipids by a mechanism that does not require a rise in cytosolic Ca2+ concentration.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Egtazic Acid; Hydrolysis; Islets of Langerhans; Male; Mass Spectrometry; Membrane Lipids; Phospholipids; Rats; Rats, Sprague-Dawley; Thapsigargin | 1998 |
Distinct effects of fatty acids on translocation of gamma- and epsilon-subspecies of protein kinase C.
Topics: Animals; Arachidonic Acid; Biological Transport; Calcium; Chelating Agents; COS Cells; Diglycerides; Egtazic Acid; Fatty Acids; Golgi Apparatus; Green Fluorescent Proteins; Indicators and Reagents; Isoenzymes; Luminescent Proteins; Protein Kinase C; Protein Kinase C-epsilon; Recombinant Fusion Proteins | 1998 |
Role of Ca2+-ATPase inhibitors in activation of cytosolic phospholipase A2 in human polymorphonuclear neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Cell-Free System; Chelating Agents; Cytosol; DNA, Complementary; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Lipid Metabolism; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Binding; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; U937 Cells | 1999 |
Induction of monocyte binding to endothelial cells by MM-LDL: role of lipoxygenase metabolites.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aorta; Arachidonic Acid; Calcium; Cell Adhesion; Chelating Agents; Cholesterol, LDL; Cyclic AMP; Cyclooxygenase Inhibitors; Egtazic Acid; Endothelium, Vascular; Humans; Lipoproteins, LDL; Lipoxygenase; Monocytes | 1999 |
N-ethylmaleimide-stimulated arachidonic acid release in human platelets.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium Signaling; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Ethylmaleimide; Genistein; Humans; In Vitro Techniques; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Reactive Oxygen Species; Signal Transduction; Sulfhydryl Reagents; Thrombin | 1999 |
Activation of the endothelin receptor inhibits the G protein-coupled inwardly rectifying potassium channel by a phospholipase A2-mediated mechanism.
Topics: Analgesics, Opioid; Animals; Anions; Arachidonic Acid; Calcium; Chelating Agents; Egtazic Acid; Endothelin-1; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gene Expression; GTP-Binding Proteins; Ion Channel Gating; Oocytes; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Rats; Receptor Cross-Talk; Receptors, Endothelin; Receptors, Muscarinic; Receptors, Opioid, mu; Staurosporine; Xenopus laevis | 1999 |
Evidence that cytosolic phospholipase A2 is down-regulated by protein kinase C in intact human platelets stimulated with fluoroaluminate.
Topics: Aluminum; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cytosol; Down-Regulation; Egtazic Acid; Enzyme Inhibitors; Fluorine; Humans; Indoles; Maleimides; Phospholipases A; Phospholipases A2; Protein Kinase C | 1999 |
Arachidonic acid induces mobilization of calcium stores and c-jun gene expression: evidence that intracellular calcium release is associated with c-jun activation.
Topics: Arachidonic Acid; Binding Sites; Biological Transport; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Gene Expression Regulation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Signal Transduction; Transcription Factor AP-1 | 1999 |
Role of phosphorylation sites and the C2 domain in regulation of cytosolic phospholipase A2.
Topics: Amino Acid Substitution; Animals; Arachidonic Acid; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Binding Sites; Calcimycin; Calcium; Cell Line; Cytosol; Egtazic Acid; Endotoxins; Enzyme Activation; Green Fluorescent Proteins; Hemolysin Proteins; Insecta; Luminescent Proteins; Nuclear Envelope; Okadaic Acid; Peptide Fragments; Phospholipases A; Phospholipases A2; Phosphorylation; Recombinant Fusion Proteins | 1999 |
Involvement of group VI Ca2+-independent phospholipase A2 in protein kinase C-dependent arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Diglycerides; Egtazic Acid; Group VI Phospholipases A2; Indoles; Leukemia P388; Maleimides; Mice; Naphthalenes; Oligonucleotides, Antisense; Organophosphonates; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrones; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zymosan | 1999 |
Arachidonic acid release in cell lines transfected with muscarinic receptors: a simple functional assay to determine response of agonists.
Topics: Animals; Arachidonic Acid; Calcium; Chelating Agents; CHO Cells; Cricetinae; Egtazic Acid; Humans; Hydrolysis; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Pirenzepine; Receptors, Muscarinic; Time Factors; Transfection | 1999 |
Thrombin-stimulated increases in cytosolic Ca2+ level and gonadotropin-releasing hormone release in GT1-7 neurons.
Topics: Animals; Arachidonic Acid; Calcium; Cell Line; Chelating Agents; Cytosol; Egtazic Acid; Gonadotropin-Releasing Hormone; Mice; Neurons; Phospholipases A; Thrombin | 1999 |
Activation of neutrophil calcium-dependent and -independent phospholipases A2 by organochlorine compounds.
Topics: Animals; Arachidonic Acid; Calcium; Chelating Agents; Dieldrin; Dose-Response Relationship, Drug; Egtazic Acid; Group VI Phospholipases A2; Hexachlorocyclohexane; Insecticides; Male; Naphthalenes; Neutrophil Activation; Neutrophils; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Pyrones; Rats; Rats, Sprague-Dawley; Superoxides | 2000 |
Potentiation of calcium levels by extracellular arachidonic acid in nuclei isolated from macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin.
Topics: alpha-Macroglobulins; Arachidonic Acid; Bradykinin; Calcium; Cell Nucleus; Chelating Agents; Cyclooxygenase Inhibitors; Cytoplasm; Egtazic Acid; Enzyme Inhibitors; Extracellular Space; Fluorescent Dyes; Fura-2; Indomethacin; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Phospholipase D; Phospholipases A; Platelet-Derived Growth Factor; Receptors, Immunologic; Signal Transduction; Thapsigargin | 2000 |
Characteristics of collagen-induced Ca2+ mobilization in bovine platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Calcium; Cattle; Collagen; Egtazic Acid; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Humans; Manganese; Phosphoadenosine Phosphosulfate; Platelet Aggregation Inhibitors; Pyrrolidinones; Thapsigargin; Thrombin; Type C Phospholipases | 2000 |
fMLP-induced arachidonic acid release in db-cAMP-differentiated HL-60 cells is independent of phosphatidylinositol-4, 5-bisphosphate-specific phospholipase C activation and cytosolic phospholipase A(2) activation.
Topics: 1-Butanol; Arachidonic Acid; Arachidonic Acids; Bacterial Proteins; Bacterial Toxins; Bridged-Ring Compounds; Bucladesine; Calcimycin; Calcium; Cell Membrane; Cytosol; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; HL-60 Cells; Humans; Indoles; Ionophores; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Norbornanes; Phosphatidylinositol 4,5-Diphosphate; Phosphodiesterase Inhibitors; Phosphoinositide Phospholipase C; Phospholipase D; Phospholipases A; Phosphoric Diester Hydrolases; Phosphorylation; Precipitin Tests; Pyrrolidinones; Thiocarbamates; Thiones; Time Factors; Type C Phospholipases | 2000 |
TGF-beta signaling in A549 lung carcinoma cells: lipid second messengers.
Topics: Acetophenones; Arachidonic Acid; Bridged-Ring Compounds; Calcium; Chelating Agents; Chromatography, Thin Layer; Diglycerides; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix; Humans; Hydrolysis; Lipids; Lung Neoplasms; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Plasmids; Protein Isoforms; Second Messenger Systems; Sphingosine; Thiocarbamates; Thiones; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured; Type C Phospholipases | 2000 |
Human lymphocytes stimulate prostacyclin synthesis in human umbilical vein endothelial cells. Involvement of endothelial cPLA2.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Arteriosclerosis; Calcium; Cell Adhesion; Cells, Cultured; Chelating Agents; Coculture Techniques; Culture Media, Conditioned; Cyclooxygenase 1; Cyclooxygenase 2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Gene Expression Regulation; Group IV Phospholipases A2; Humans; Infant, Newborn; Intramolecular Oxidoreductases; Isoenzymes; Lipopolysaccharides; Lymphocytes; Membrane Proteins; Organophosphonates; Phospholipases A; Phospholipases A2; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Tranylcypromine; Umbilical Veins | 2000 |
The Ca2+-sensing receptor activates cytosolic phospholipase A2 via a Gqalpha -dependent ERK-independent pathway.
Topics: Arachidonic Acid; Arachidonic Acids; Benzylamines; Binding, Competitive; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Genes, Dominant; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Immunoblotting; Inhibitory Concentration 50; Kinetics; Mitogen-Activated Protein Kinases; Mutation; Naphthalenes; Pertussis Toxin; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Protein Binding; Protein Kinase C; Pyrones; Pyrrolidinones; Receptors, Calcium-Sensing; Receptors, Cell Surface; RGS Proteins; Signal Transduction; Spectrometry, Fluorescence; Sulfonamides; Time Factors; Transfection; Type C Phospholipases; Virulence Factors, Bordetella | 2001 |
Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Arachidonic Acid; beta-Defensins; Calcium; Calcium Signaling; Carrier Proteins; Cathelicidins; Chelating Agents; Cyclooxygenase Inhibitors; Egtazic Acid; Estrenes; Histamine; Humans; Magnesium; Male; Mast Cells; Molecular Sequence Data; Pertussis Toxin; Prostaglandin D2; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Virulence Factors, Bordetella | 2001 |
Enhancement of arachidonic acid release and prostaglandin F(2alpha) formation by Na3VO4 in PC12 cells and GH3 cells.
Topics: Animals; Arachidonic Acid; Chelating Agents; Cytosol; Dinoprost; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Hydrogen Peroxide; Intercellular Signaling Peptides and Proteins; Ionomycin; PC12 Cells; Peptides; Phospholipases A; Phospholipases A2; Rats; Tumor Cells, Cultured; Vanadates; Wasp Venoms | 2001 |
Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Androstadienes; Animals; Arachidonic Acid; Arachidonic Acids; Butadienes; Calcium; Carbazoles; Chelating Agents; Chromones; Cyclooxygenase Inhibitors; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Indoles; Lipoxygenase Inhibitors; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neutrophils; Nitriles; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin | 2001 |
Regulation of eosinophil function by phosphatidylinositol-specific PLC and cytosolic PLA(2).
Topics: Arachidonic Acid; Biomarkers; Calcium; Chelating Agents; Cytosol; Egtazic Acid; Eosinophil Peroxidase; Eosinophils; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Ketones; Leukotriene C4; Peroxidases; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phosphoinositide Phospholipase C; Phospholipase C beta; Phospholipase C gamma; Phospholipases A; Phospholipid Ethers; Protein Kinase C; Type C Phospholipases; Virulence Factors, Bordetella | 2001 |
Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization.
Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Culture Media; Dithionitrobenzoic Acid; Dithiothreitol; Edetic Acid; Egtazic Acid; Endocannabinoids; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hydrolysis; Lipid Metabolism; Magnesium; Phenylmethylsulfonyl Fluoride; Phospholipids; Polyunsaturated Alkamides; Temperature; Tetrahymena pyriformis | 2001 |
Zona pellucida induces activation of phospholipase A2 during acrosomal exocytosis in guinea pig spermatozoa.
Topics: Acrosome Reaction; Animals; Arachidonic Acid; Aristolochic Acids; Calcium; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Female; Guinea Pigs; Lanthanum; Lysophosphatidylcholines; Male; Pertussis Toxin; Phospholipases A; Phospholipases A2; Pyrimidinones; Sperm Capacitation; Spermatozoa; Thiazoles; Zona Pellucida | 2003 |
Creating conditions similar to those that occur during exposure of cells to microgravity induces apoptosis in human lymphocytes by 5-lipoxygenase-mediated mitochondrial uncoupling and cytochrome c release.
Topics: Adult; Amino Acid Chloromethyl Ketones; Apoptosis; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Caspase 3; Caspase 9; Caspase Inhibitors; Cysteine Proteinase Inhibitors; Cytochrome c Group; Egtazic Acid; Enzyme Inhibitors; Humans; Lipoxygenase Inhibitors; Lymphocytes; Membrane Potentials; Mitochondria; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; U937 Cells; Weightlessness Simulation | 2003 |
Essential role of EDHF in the initiation and maintenance of adrenergic vasomotion in rat mesenteric arteries.
Topics: Adrenergic alpha-Agonists; Animals; Apamin; Arachidonic Acid; Biological Factors; Buffers; Calcium; Charybdotoxin; Chelating Agents; Cyclic GMP; Egtazic Acid; Endothelium, Vascular; Histological Techniques; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasomotor System | 2004 |
Mechanisms of the influence of magnolol on eicosanoid metabolism in neutrophils.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Biological Transport; Biphenyl Compounds; Cell Membrane; Egtazic Acid; Eicosanoids; Enzyme Activation; In Vitro Techniques; Lignans; Mitogen-Activated Protein Kinases; Neutrophils; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Rats | 2004 |
Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Amino Acid Motifs; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Blood Platelets; Calcimycin; Calcium Signaling; Carrier Proteins; Collagen; Cyclooxygenase 1; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Inflammation; Isoenzymes; Leukotrienes; Membrane Proteins; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Platelet Activation; Platelet Endothelial Cell Adhesion Molecule-1; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport; Quinolines; Receptors, IgG; Thrombin | 2004 |
Calcium transients in astrocyte endfeet cause cerebrovascular constrictions.
Topics: Animals; Arachidonic Acid; Arterioles; Astrocytes; Brain; Calcium Signaling; Cerebrovascular Circulation; Egtazic Acid; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Mice; Mice, Transgenic; Norepinephrine; Patch-Clamp Techniques; Phospholipases A; Photolysis; Photons; Rats; Vasoconstriction | 2004 |
Late-gestation rat myometrial cells express multiple isoforms of phospholipase A2 that mediate PCB 50-induced release of arachidonic acid with coincident prostaglandin production.
Topics: Animals; Arachidonic Acid; Calcium Channels, L-Type; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Environmental Pollutants; Enzyme Inhibitors; Female; Fetus; Imidazoles; Myometrium; Nifedipine; Phospholipases A; Phospholipases A2; Polychlorinated Biphenyls; Pregnancy; Prostaglandins; Pyridines; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms | 2005 |
Regulation of tissue transglutaminase by prolonged increase of intracellular Ca2+, but not by initial peak of transient Ca2+ increase.
Topics: Animals; Arachidonic Acid; Calcium; Cations, Divalent; Cell Line, Tumor; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Intracellular Space; Lysophospholipids; Marine Toxins; Mice; Oxocins; RNA, Small Interfering; Time Factors; Transglutaminases | 2005 |
Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Biological Transport; Calcium; Chelating Agents; Cyclic AMP; Egtazic Acid; Humans; Leukotrienes; Lipoxygenase Inhibitors; Neutrophils; Nuclear Envelope | 2006 |
Effect of prednisolone on secondary messenger metabolism in the lymphocytes from patients with acantholysis bullosa.
Topics: Arachidonic Acid; Calcium; Cyclic AMP; Egtazic Acid; Epidermolysis Bullosa; Humans; Lymphocytes; Prednisolone; Second Messenger Systems | 2005 |
Arachidonic acid is a chemoattractant for Dictyostelium discoideum cells.
Topics: Animals; Arachidonic Acid; Calcium; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Egtazic Acid; Mutation | 2007 |
Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells.
Topics: Arachidonic Acid; Arachidonic Acids; Boron Compounds; Breast; Calcium Channel Blockers; Cell Line, Transformed; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Nifedipine; Organophosphonates; Phospholipases A2, Cytosolic; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; RNA, Small Interfering; src-Family Kinases; Time Factors; Transfection | 2008 |
Association with actin mediates the EGTA-resistant binding of cytosolic phospholipase A2-alpha to the plasma membrane of activated platelets.
Topics: Actin Cytoskeleton; Actins; Arachidonic Acid; Blood Platelets; Cell Membrane; Deoxyribonuclease I; Egtazic Acid; Group IV Phospholipases A2; Humans; Immunoprecipitation; Microscopy, Fluorescence; Platelet Activation; Protein Transport; Thrombin; Thromboxane A2; Time Factors | 2009 |
TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Diglycerides; Drug Synergism; Edetic Acid; Egtazic Acid; Enzyme Activation; Group IV Phospholipases A2; Lipopolysaccharides; Macrophages; Mice; Naphthalenes; Pancreatitis-Associated Proteins; Phosphatidate Phosphatase; Propranolol; Protein Kinase C; Pyrones; Time Factors; Toll-Like Receptor 4 | 2009 |
Nanomolar vitamin E alpha-tocotrienol inhibits glutamate-induced activation of phospholipase A2 and causes neuroprotection.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Death; Cell Line, Transformed; Cell Size; Chelating Agents; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Fatty Acids; Glutamic Acid; Hippocampus; Mice; Neurons; Neuroprotective Agents; Phospholipase A2 Inhibitors; Phospholipases A2; RNA, Small Interfering; Subcellular Fractions; Tocotrienols; Transfection; Vitamin E | 2010 |
Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms.
Topics: Animals; Arachidonic Acid; Calcium; Cell Line, Tumor; Egtazic Acid; Glioma; Glycosylphosphatidylinositols; Histamine; Phosphatidylinositols; Phospholipases A2; Pyrilamine; Rats; Receptors, Histamine H1; Signal Transduction | 2012 |
Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation.
Topics: Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Transformed; Chelating Agents; Cyclosporine; Diglycerides; Egtazic Acid; Fibroblasts; Group IV Phospholipases A2; Isoenzymes; L-Lactate Dehydrogenase; Mice; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Phospholipase A2 Inhibitors; Pyrrolidines; Thapsigargin | 2014 |
Airborne agricultural particulate matter induces inflammatory cytokine secretion by respiratory epithelial cells: mechanisms of regulation by eicosanoid lipid signal mediators.
Topics: Agriculture; Animals; Antioxidants; Arachidonic Acid; Biocatalysis; Cell Line; Cytokines; Dose-Response Relationship, Drug; Egtazic Acid; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Humans; Inflammation; Interleukin-8; Lipoxygenases; Particulate Matter; Phospholipases A2, Cytosolic; Poultry; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Respiratory Mucosa; Signal Transduction; Solvents; Time Factors | 2013 |