egtazic acid has been researched along with 4-aminopyridine in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (19.48) | 18.7374 |
| 1990's | 36 (46.75) | 18.2507 |
| 2000's | 19 (24.68) | 29.6817 |
| 2010's | 7 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Calabrese, RL; Opdyke, CA; Simon, TW | 1 |
| Beauvais, F; Benveniste, J; Burtin, C; Hieblot, C; Inoue, I; Shimahara, T | 1 |
| McMahon, HT; Nicholls, DG | 1 |
| Barrett, EF; Morita, K | 1 |
| Luk'ianets, EA | 1 |
| Eliasson, SG; Monafo, WW | 1 |
| Brown, DA; Marsh, SJ | 1 |
| Matsuda, JJ; Shibata, EF; Volk, KA | 1 |
| Hartung, K | 1 |
| Tapia, R | 1 |
| Ichinose, M; Maeno, T; Sawada, M | 1 |
| Dekin, MS; Getting, PA | 1 |
| Imaizumi, Y; Muraki, K; Watanabe, M | 1 |
| Alkon, DL; Coulter, DA; Disterhoft, JF; Kubota, M; Lo Turco, JJ; Moore, JW | 1 |
| Krnjevic, K; Leblond, J | 1 |
| Hiraoka, M; Kawano, S | 1 |
| Savage, AO | 1 |
| del Castillo, J; Hernandez, ZM; Morales, M; Smith, DS | 1 |
| Quastel, DM; Saint, DA | 1 |
| Bikhazi, GB; Flores, C; Foldes, FF | 1 |
| Galatulas, I; Gibelli, N; Supino, R; Zunino, F | 1 |
| Ohkawa, H | 1 |
| Tachibana, M | 1 |
| Husted, RF; Pruchno, CJ; Stokes, JB; Volk, KA | 1 |
| Chen, W; Hui, CS | 1 |
| del Pilar Gomez, M; Nasi, E | 1 |
| Akbarali, HI; Goyal, RK; Hatakeyama, N; Wang, Q | 1 |
| Gelband, CH; Hume, JR; Ishikawa, T; Keef, KD; Post, JM | 1 |
| Cognard, C; Constantin, B; Raymond, G; Rivet-Bastide, M | 1 |
| Chen, S; Inoue, R; Ito, Y | 1 |
| Kunze, DL; Moak, JP | 1 |
| Zygmunt, AC | 1 |
| Clausen, C; Goligorsky, MS; Gordienko, DV | 1 |
| Beech, DJ; Sadraei, H | 1 |
| Hamamura, I; Isohama, Y; Kai, H; Miyata, T; Murahara, K; Oda, Y; Takahama, K; Yoshitake, K | 1 |
| Cheng-Wen, Z; Hua-Yu, H; Yu-Liang, S | 1 |
| Malenka, RC; Nicoll, RA; Salin, PA; Scanziani, M | 1 |
| Horimoto, N; Nabekura, J; Ogawa, T | 1 |
| Arita, M; Kiyosue, T; Sato, T; Shigematsu, S | 1 |
| Bryant, SM; Hart, G; Shipsey, SJ | 1 |
| Boyett, MR; Harrison, SM; Janvier, NC; McMorn, SO; Taggart, P | 1 |
| Driesang, RB; Pape, HC | 1 |
| Huang, HY; Zhou, CW | 1 |
| Bolotina, VM; Cohen, RA; Mongayt, DA; Zakharov, SI | 1 |
| Alexandre, A; Cavallini, L; Zoccarato, F | 1 |
| Beirão, PS; Cordeiro, MN; Cruz, JS; Diniz, CR; Gomez, MV; Kalapothakis, E; Kushmerick, C; Penaforte, CL; Prado, MA; Prado, VF; Romano-Silva, MA | 1 |
| Farrukh, IS; Hoidal, JR; Peng, W | 1 |
| Ashmore, JF; Jagger, DJ | 1 |
| Jensen, K; Jensen, MS; Lambert, JD | 1 |
| McGinty, JF; Rawls, SM; Terrian, DM | 1 |
| Garland, CJ; Mistry, DK | 1 |
| Jung, MW; Kang, GH; Kang, YS; Kim, JA; Lee, SH; Lee, YS | 1 |
| DuBell, WH; Lederer, WJ; Rogers, TB | 1 |
| Duridanova, D; Gagov, H; Krien, U; Noack, T; Petkova-Kirova, P; Schubert, R | 1 |
| Charles, AC; Costantin, JL | 1 |
| Tang, G; Wang, R | 1 |
| Diamant, NE; Ji, J; Salapatek, AM | 1 |
| Beekenkamp, H; Bossu, JL; Cavelier, P; Desplantez, T; Pouille, F | 1 |
| Flameng, W; Macianskiene, R; Moccia, F; Mubagwa, K; Sipido, KR | 1 |
| Hisatome, I; Imanishi, S; Kurata, Y; Shibamoto, T | 1 |
| Deitch, EA; Kim, SJ; Vatner, SF; Xu, DZ; Yatani, A | 1 |
| Liu, X; Stan Leung, L | 1 |
| Jiang, L; Kang, J; Kang, N; Nedergaard, M; Xu, J | 1 |
| Annunziato, L; Calì, G; Pannaccione, A; Scorziello, A; Secondo, A; Taglialatela, M | 1 |
| Inoue, M; Kudo, Y; Miyakawa, H; Miyazaki, K; Murayama, M | 1 |
| Patuzzi, R; Robertson, D; Sellick, PM | 1 |
| Ayala, GX; Tapia, R | 1 |
| Bae, YM; Cho, SI; Kim, A; Kim, B; Kim, J; Kim, TK; Lee, YR; Park, SW | 1 |
| Adaramoye, OA; Medeiros, IA | 1 |
| Brondi, M; Cammarota, M; Carmignoto, G; Chiavegato, A; de Curtis, M; Gómez-Gonzalo, M; Losi, G; Pozzan, T; Ratto, GM; Uva, L; Vetri, F; Zonta, M | 1 |
| Cheng, J; Keskanokwong, T; Lai, D; Lim, HJ; Wang, Y; Xu, L; Zhang, P | 1 |
| Ikegaya, Y; Matsuki, N; Sasaki, T | 1 |
| Nair, SS; Ransdell, JL; Schulz, DJ | 1 |
| Lin, TY; Lu, CW; Wang, SJ | 1 |
| Chang, CY; Chou, SS; Huang, SK; Lin, TY; Lu, CW; Wang, SJ; Wang, YC | 1 |
| Azamfirei, L; Baranyi, M; Borbély, Z; Lazar, A; Sircuta, C; Vizi, ES | 1 |
1 review(s) available for egtazic acid and 4-aminopyridine
| Article | Year |
|---|---|
Effects of drugs on neurotransmitter release: experiments in vivo and in vitro.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cell Membrane Permeability; Edetic Acid; Egtazic Acid; gamma-Aminobutyric Acid; Lanthanum; Mice; Motor Activity; Neurotransmitter Agents; Ruthenium Red; Sodium; Substantia Nigra; Synapses; Synaptosomes; Veratridine | 1985 |
76 other study(ies) available for egtazic acid and 4-aminopyridine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Modulatory effects of FMRF-NH2 on outward currents and oscillatory activity in heart interneurons of the medicinal leech.
Topics: 4-Aminopyridine; Animals; Calcium; Cobalt; Egtazic Acid; Electric Conductivity; Evoked Potentials; FMRFamide; Ganglia; Heart Conduction System; In Vitro Techniques; Interneurons; Invertebrate Hormones; Kinetics; Leeches; Neuropeptides; Neurotransmitter Agents; Sodium; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Regulation of human basophil activation. II. Histamine release is potentiated by K+ efflux and inhibited by Na+ influx.
Topics: 4-Aminopyridine; Basophils; Calcium; Egtazic Acid; Gramicidin; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Potassium; Potassium Channels; Quinidine; Sodium; Sparteine; Valinomycin | 1992 |
Transmitter glutamate release from isolated nerve terminals: evidence for biphasic release and triggering by localized Ca2+.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Calcium; Calcium Radioisotopes; Cerebral Cortex; Egtazic Acid; Exocytosis; Glutamates; Glutamic Acid; Guinea Pigs; Ionomycin; Kinetics; Nerve Endings; Potassium Chloride; Spectrometry, Fluorescence; Synaptosomes | 1991 |
Evidence for two calcium-dependent potassium conductances in lizard motor nerve terminals.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Action Potentials; Animals; Apamin; Caffeine; Calcium; Charybdotoxin; Egtazic Acid; Electric Conductivity; Lizards; Motor Neurons; Muscle Contraction; Nerve Endings; Potassium; Procaine; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1990 |
[The effect of intracellular calcium on an increase in the cAMP-mediated calcium current].
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Animals; Calcium; Calcium Channels; Creatinine; Cyclic AMP; Drug Combinations; Drug Interactions; Egtazic Acid; Helix, Snails; In Vitro Techniques; Membrane Potentials; Neurons; Serotonin; Theophylline; Trifluoperazine | 1991 |
Effects of 4-aminopyridine on protein phosphorylation in heat-blocked peripheral nerve.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Calcium; Egtazic Acid; Electric Stimulation; Hot Temperature; Kinetics; Molecular Weight; Nerve Block; Nerve Tissue Proteins; Peripheral Nerves; Peroneal Nerve; Phosphoproteins; Phosphorylation; Rats; Rats, Inbred Strains; Sural Nerve; Tibial Nerve | 1991 |
Potassium currents contributing to action potential repolarization in dissociated cultured rat superior cervical sympathetic neurones.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cadmium; Cadmium Chloride; Calcium; Cells, Cultured; Chlorides; Egtazic Acid; Ganglia, Sympathetic; Kinetics; Neurons; Potassium Channels; Rats; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
A voltage-dependent potassium current in rabbit coronary artery smooth muscle cells.
Topics: 4-Aminopyridine; Animals; Calcium; Coronary Vessels; Egtazic Acid; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Channels; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
Potentiation of a transient outward current by Na+ influx in crayfish neurones.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Astacoidea; Egtazic Acid; Ion Channels; Motor Neurons; Ouabain; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
Ionic mechanism of the outward current induced by intracellular injection of inositol trisphosphate into Aplysia neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aplysia; Calcium; Chlorides; Egtazic Acid; Electric Conductivity; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ion Channels; Membrane Potentials; Neurons; Potassium; Sugar Phosphates; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
In vitro characterization of neurons in the ventral part of the nucleus tractus solitarius. II. Ionic basis for repetitive firing patterns.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Egtazic Acid; Guinea Pigs; In Vitro Techniques; Ion Channels; Medulla Oblongata; Potassium; Respiratory Center | 1987 |
Ionic currents in single smooth muscle cells from the ureter of the guinea-pig.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cadmium; Caffeine; Calcium Channel Blockers; Egtazic Acid; Guinea Pigs; In Vitro Techniques; Ion Channels; Lithium; Muscle, Smooth; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Ureter | 1989 |
Classical conditioning reduces amplitude and duration of calcium-dependent afterhyperpolarization in rabbit hippocampal pyramidal cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cadmium; Cadmium Chloride; Calcium; Carbachol; Cobalt; Conditioning, Classical; Egtazic Acid; Electroshock; Hippocampus; In Vitro Techniques; Male; Pyramidal Tracts; Rabbits; Reference Values; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1989 |
Hypoxic changes in hippocampal neurons.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Apamin; Caffeine; Calcium; Egtazic Acid; Electric Stimulation; Hippocampus; Hypoxia; Membrane Potentials; Neuroglia; Neuromuscular Depolarizing Agents; Neurons; Nitrogen; Quinine; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Tolbutamide | 1989 |
Calcium-sensitive and insensitive transient outward current in rabbit ventricular myocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Caffeine; Calcium; Egtazic Acid; Heart; In Vitro Techniques; Membrane Potentials; Potassium; Rabbits; Ryanodine; Tetrodotoxin | 1989 |
A comparison of the actions of 4-aminopyridine, caffeine and quinine on the toad isolated rectus abdominis muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bufonidae; Caffeine; Egtazic Acid; In Vitro Techniques; Manganese; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Potassium; Procaine; Quinine; Verapamil | 1989 |
Barium spikes are generated in the spines of the sea urchin Diadema antillarum.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Barium; Calcium; Edetic Acid; Egtazic Acid; Sea Urchins; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Transmitter release at mouse motor nerve terminals mediated by temporary accumulation of intracellular barium.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Egtazic Acid; In Vitro Techniques; Magnesium; Mice; Motor Endplate; Muscles; Neomycin; Neuromuscular Junction; Neurotransmitter Agents; Ranidae; Tetrodotoxin; Time Factors | 1988 |
The effect of verapamil and EGTA on the rat phrenic nerve-hemidiaphragm preparation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Diaphragm; Egtazic Acid; Electric Stimulation; Ethylene Glycols; In Vitro Techniques; Male; Neostigmine; Neuromuscular Junction; Phrenic Nerve; Rats; Rats, Inbred Strains; Synaptic Transmission; Verapamil | 1985 |
Influence of calcium and calcium-modulating agents on differentiation of murine erythroleukaemia cells.
Topics: 4-Aminopyridine; Aminopyridines; Amrinone; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Egtazic Acid; Erythrocytes; Erythropoiesis; Friend murine leukemia virus; Gallic Acid; Leukemia, Erythroblastic, Acute; Mice; Razoxane; Verapamil | 1985 |
Effects of 4-aminopyridine on the non-adrenergic inhibitory neurotransmission in the guinea-pig duodenum.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Central Nervous System Stimulants; Duodenum; Egtazic Acid; Evoked Potentials; Female; Guinea Pigs; Male; Membrane Potentials; Muscle, Smooth; Neural Inhibition; Synaptic Transmission; Tetraethylammonium Compounds; Verapamil | 1984 |
Ionic currents of solitary horizontal cells isolated from goldfish retina.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Calcium; Cells, Cultured; Cyprinidae; Egtazic Acid; Goldfish; Interneurons; Membrane Potentials; Potassium; Retina; Tetraethylammonium Compounds | 1983 |
Functional and molecular evidence for Shaker-like K+ channels in rabbit renal papillary epithelial cell line.
Topics: 4-Aminopyridine; Amiloride; Animals; Base Sequence; Calcium; Cell Line; Charybdotoxin; DNA Primers; Drosophila; Egtazic Acid; Elapid Venoms; Epithelium; Kidney Medulla; Kidney Tubules, Collecting; Membrane Potentials; Models, Biological; Molecular Sequence Data; Nephrons; Pancreatitis-Associated Proteins; Polymerase Chain Reaction; Potassium; Potassium Channel Blockers; Potassium Channels; Rabbits; RNA, Messenger; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Origin of delayed outward ionic current in charge movement traces from frog skeletal muscle.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Aminopyridine; Amifampridine; Animals; Anions; Calcium; Cesium; Chloride Channels; Egtazic Acid; Furosemide; Gluconates; Glutamic Acid; Ion Channels; Muscle, Skeletal; Rana temporaria; Rubidium; Tetradecanoylphorbol Acetate; Tetrodotoxin; Time Factors | 1994 |
Activation of light-dependent K+ channels in ciliary invertebrate photoreceptors involves cGMP but not the IP3/Ca2+ cascade.
Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Egtazic Acid; Electric Conductivity; Heparin; Inositol Phosphates; Light; Mollusca; Photoreceptor Cells, Invertebrate; Potassium Channels; Vanadates | 1995 |
Transient outward current in opossum esophageal circular muscle.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cadmium; Calcium Channels; Egtazic Acid; Esophagus; In Vitro Techniques; Membrane Potentials; Muscle, Smooth; Nifedipine; Opossums; Patch-Clamp Techniques; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Intracellular divalent cations block smooth muscle K+ channels.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channels; Charybdotoxin; Dogs; Egtazic Acid; Electrophysiology; Magnesium; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Channels; Pyridines; Rabbits; Ryanodine; Scorpion Venoms | 1993 |
Activation of a slow outward current by the calcium released during contraction of cultured rat skeletal muscle cells.
Topics: 4-Aminopyridine; Animals; Apamin; Caffeine; Calcium; Cells, Cultured; Cesium; Charybdotoxin; Egtazic Acid; Electric Conductivity; Electric Stimulation; Membrane Potentials; Muscle Contraction; Muscles; Nifedipine; Potassium; Rats; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1993 |
Pharmacological characterization of muscarinic receptor-activated cation channels in guinea-pig ileum.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Caffeine; Calcium Channels; Diphenylamine; Egtazic Acid; Electrophysiology; Female; Flufenamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Muscle, Smooth; Nystatin; Procaine; Quinine; Receptors, Muscarinic; Tetraethylammonium Compounds | 1993 |
Potassium currents of neurons isolated from medical nucleus tractus solitarius.
Topics: 4-Aminopyridine; Animals; Apamin; Calcium; Charybdotoxin; Egtazic Acid; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Neurons; Potassium Channels; Scorpion Venoms; Solitary Nucleus; Tetraethylammonium; Tetraethylammonium Compounds; Tubocurarine | 1993 |
Intracellular calcium activates a chloride current in canine ventricular myocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Aminopyridine; Animals; Caffeine; Calcimycin; Calcium; Calcium Channels; Calcium Chloride; Cells, Cultured; Diacetyl; Dogs; Egtazic Acid; Electrophysiology; Female; Heart; Heart Ventricles; Isoproterenol; Kinetics; Male; Meglumine; Membrane Potentials; Time Factors | 1994 |
Ionic currents and endothelin signaling in smooth muscle cells from rat renal resistance arteries.
Topics: 4-Aminopyridine; Animals; Arterioles; Caffeine; Calcium; Cell Membrane; Cobalt; Egtazic Acid; Electric Conductivity; Endothelins; Fluorescent Dyes; Fura-2; In Vitro Techniques; Kidney; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Renal Circulation; Signal Transduction; Spectrometry, Fluorescence; Tetraethylammonium; Tetraethylammonium Compounds; Vascular Resistance | 1994 |
Ionic currents and inhibitory effects of glibenclamide in seminal vesicle smooth muscle cells.
Topics: 4-Aminopyridine; Amifampridine; Animals; Barium; Biological Transport, Active; Cadmium; Calcium; Calcium Channels; Egtazic Acid; Electric Stimulation; Glyburide; Guinea Pigs; Hypoglycemic Agents; Ion Transport; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Chloride; Seminal Vesicles; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Pyridine derivatives stimulate phosphatidylcholine secretion in primary cultures of rat type II pneumocytes.
Topics: 4-Aminopyridine; Animals; Calcium; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; L-Lactate Dehydrogenase; Lung; Male; Phosphatidylcholines; Pyridines; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Structure-Activity Relationship; Sulfonamides; Vasodilator Agents | 1996 |
Toosendanin facilitates [3H]noradrenaline release from rat hippocampal slices.
Topics: 4-Aminopyridine; Amifampridine; Animals; Calcium; Chelating Agents; Dantrolene; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Egtazic Acid; Hippocampus; In Vitro Techniques; Isotope Labeling; Muscle Relaxants, Central; Neuromuscular Blocking Agents; Norepinephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Reserpine; Sympatholytics; Tritium | 1996 |
Distinct short-term plasticity at two excitatory synapses in the hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Magnesium; Nerve Fibers; Neuronal Plasticity; Neurons; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 1996 |
Arachidonic acid activation of potassium channels in rat visual cortex neurons.
Topics: 4-Aminopyridine; Animals; Apamin; Arachidonic Acid; Barium; Charybdotoxin; Docosahexaenoic Acids; Egtazic Acid; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Glyburide; In Vitro Techniques; Indomethacin; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Quinidine; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds; Visual Cortex | 1997 |
Rate-dependent prolongation of action potential duration in isolated rat ventricular myocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Cell Separation; Chelating Agents; Egtazic Acid; Intracellular Membranes; Male; Papillary Muscles; Patch-Clamp Techniques; Rats; Rats, Wistar; Reaction Time; Ventricular Function | 1997 |
Effects of hypertrophy on regional action potential characteristics in the rat left ventricle: a cellular basis for T-wave inversion?
Topics: 4-Aminopyridine; Action Potentials; Animals; Cell Membrane; Chelating Agents; Disease Models, Animal; Egtazic Acid; Electric Conductivity; Electrocardiography; Endocardium; Heart Conduction System; Hypertrophy, Left Ventricular; In Vitro Techniques; Isotonic Solutions; Male; Muscle Fibers, Skeletal; Organ Size; Rats; Rats, Wistar | 1997 |
The role of Na(+)-Ca2+ exchange current in electrical restitution in ferret ventricular cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Egtazic Acid; Electric Stimulation; Female; Ferrets; Heart Ventricles; Kinetics; Male; Myocardial Contraction; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Rats; Sodium; Sodium-Calcium Exchanger | 1997 |
Ionic mechanisms of intrinsic oscillations in neurons of the basolateral amygdaloid complex.
Topics: 4-Aminopyridine; Amygdala; Animals; Apamin; Barium; Calcium; Cations, Divalent; Cesium; Charybdotoxin; Egtazic Acid; Evoked Potentials; Fourier Analysis; Guinea Pigs; In Vitro Techniques; Magnesium; Membrane Potentials; Neurons; Oscillometry; Peptides; Sodium; Tetraethylammonium; Tetrodotoxin | 1998 |
Involvement of intracellular Ca2+ stores in 3,4-diaminopyridine-evoked [3H]norepinephrine release.
Topics: 4-Aminopyridine; Amifampridine; Animals; Calcium; Chelating Agents; Desipramine; Egtazic Acid; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Reserpine | 1996 |
Monovalent cation and L-type Ca2+ channels participate in calcium paradox-like phenomenon in rabbit aortic smooth muscle cells.
Topics: 4-Aminopyridine; Animals; Aorta; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cations, Monovalent; Cesium; Chelating Agents; Egtazic Acid; Glutamine; Imidazoles; Lithium; Magnesium; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Penicillamine; Potassium; Rabbits; Sodium; Tetraethylammonium; Vasoconstriction | 1999 |
The pH-sensitive dye acridine orange as a tool to monitor exocytosis/endocytosis in synaptosomes.
Topics: 4-Aminopyridine; Acids; Acridine Orange; Animals; Anti-Bacterial Agents; Biological Transport; Cadmium; Calcium; Cerebral Cortex; Chelating Agents; Dimerization; Egtazic Acid; Endocytosis; Exocytosis; Fluorescent Dyes; Glutamic Acid; Hydrogen-Ion Concentration; Macrolides; Neurons; Neurotransmitter Agents; Potassium Chloride; Rats; Synaptic Vesicles; Synaptosomes; Tetrodotoxin | 1999 |
Phoneutria nigriventer toxin Tx3-1 blocks A-type K+ currents controlling Ca2+ oscillation frequency in GH3 cells.
Topics: 4-Aminopyridine; Amino Acid Sequence; Base Sequence; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Charybdotoxin; Chelating Agents; DNA, Complementary; Egtazic Acid; Ion Channel Gating; Membrane Potentials; Molecular Sequence Data; Neuropeptides; Nifedipine; Patch-Clamp Techniques; Periodicity; Pituitary Gland; Potassium Channel Blockers; Potassium Channels; Spider Venoms | 1999 |
Role of a novel KCa opener in regulating K+ channels of hypoxic human pulmonary vascular cells.
Topics: 4-Aminopyridine; Cell Hypoxia; Cells, Cultured; Charybdotoxin; Cyclic AMP; Cyclic GMP; Dehydroepiandrosterone; Egtazic Acid; Enzyme Inhibitors; Humans; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated; Protein Kinase Inhibitors; Pulmonary Circulation; Thionucleotides | 1999 |
The fast activating potassium current, I(K,f), in guinea-pig inner hair cells is regulated by protein kinase A.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Inhibitors; Guinea Pigs; Hair Cells, Auditory, Inner; In Vitro Techniques; Isoquinolines; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Sulfonamides | 1999 |
Activity-dependent depression of GABAergic IPSCs in cultured hippocampal neurons.
Topics: 4-Aminopyridine; Animals; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Electric Stimulation; Evoked Potentials; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Neurons; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Synaptic Transmission | 1999 |
Presynaptic kappa-opioid and muscarinic receptors inhibit the calcium-dependent component of evoked glutamate release from striatal synaptosomes.
Topics: 4-Aminopyridine; Animals; Calcium; Chelating Agents; Dicarboxylic Acids; Egtazic Acid; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glutamic Acid; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Naltrexone; Narcotic Antagonists; Neostriatum; Nerve Endings; Neurotransmitter Uptake Inhibitors; Potassium Channel Blockers; Potassium Channels; Pyrrolidines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Opioid, kappa; Receptors, Presynaptic; Synaptosomes | 1999 |
The influence of phenylephrine outward potassium currents in single smooth muscle cells from the rabbit mesenteric artery.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Amifampridine; Animals; Caffeine; Calcium; Chelating Agents; Drug Interactions; Egtazic Acid; Female; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Potassium Channels; Prazosin; Rabbits; Tetraethylammonium; Vasoconstrictor Agents | 1999 |
Ca2+ influx mediates apoptosis induced by 4-aminopyridine, a K+ channel blocker, in HepG2 human hepatoblastoma cells.
Topics: 4-Aminopyridine; Apoptosis; Calcium; Calcium Channel Blockers; Cell Survival; Chelating Agents; DNA Fragmentation; Egtazic Acid; Flufenamic Acid; Hepatoblastoma; Humans; Liver Neoplasms; Manganese; Membrane Potentials; Nifedipine; Potassium Channel Blockers; Potassium Channels; Tumor Cells, Cultured; Verapamil | 2000 |
K(+) currents responsible for repolarization in mouse ventricle and their modulation by FK-506 and rapamycin.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Egtazic Acid; Electric Conductivity; Heart; Immunosuppressive Agents; Mice; Mice, Transgenic; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Sirolimus; Tacrolimus; Tetraethylammonium; Ventricular Function | 2000 |
4-aminopyridine affects rat arterial smooth muscle BK(Ca) currents by changing intracellular pH.
Topics: 4-Aminopyridine; Animals; Arteries; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Hydrogen-Ion Concentration; Male; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Rats, Inbred WKY; Small-Conductance Calcium-Activated Potassium Channels | 2000 |
Modulation of Ca(2+) signaling by K(+) channels in a hypothalamic neuronal cell line (GT1-1).
Topics: 4-Aminopyridine; Action Potentials; Animals; Barium; Calcium; Calcium Signaling; Cell Line; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Hypothalamus; Mice; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Sodium Channel Blockers; Tetraethylammonium | 2001 |
Differential expression of KV and KCa channels in vascular smooth muscle cells during 1-day culture.
Topics: 4-Aminopyridine; Animals; Arteries; Calcimycin; Cells, Cultured; Chelating Agents; Egtazic Acid; Electric Conductivity; Ionophores; Male; Membrane Potentials; Muscle, Smooth, Vascular; Peptides; Potassium Channels; Rats; Rats, Sprague-Dawley; Tail; Tetraethylammonium | 2001 |
Ion channel diversity in the feline smooth muscle esophagus.
Topics: 4-Aminopyridine; Animals; Cats; Chelating Agents; Delayed Rectifier Potassium Channels; Egtazic Acid; Elapid Venoms; Esophagus; Female; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Smooth; Patch-Clamp Techniques; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Tetraethylammonium | 2002 |
Control of the propagation of dendritic low-threshold Ca(2+) spikes in Purkinje cells from rat cerebellar slice cultures.
Topics: 4-Aminopyridine; Action Potentials; Agatoxins; Anesthetics, Local; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cerebellum; Chelating Agents; Dendrites; Egtazic Acid; Evoked Potentials; Organ Culture Techniques; Potassium Channel Blockers; Purkinje Cells; Rats; Rats, Wistar; Spider Venoms; Tetraethylammonium; Tetrodotoxin | 2002 |
Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cesium; Chelating Agents; Diltiazem; Drug Resistance; Egtazic Acid; Electric Conductivity; Heart Ventricles; Isoproterenol; Kinetics; Magnesium; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Receptors, Adrenergic, beta; Swine; Verapamil | 2002 |
Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell.
Topics: 4-Aminopyridine; Animals; Biological Clocks; Calcium; Chelating Agents; Computer Simulation; Egtazic Acid; Models, Cardiovascular; Nonlinear Dynamics; Potassium; Potassium Channel Blockers; Rabbits; Sarcolemma; Sinoatrial Node | 2002 |
Mesenteric lymph from rats with thermal injury prolongs the action potential and increases Ca2+ transient in rat ventricular myocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Burns; Caffeine; Calcium; Calcium Channels, T-Type; Egtazic Acid; Electrophysiology; Lithium; Lymph; Male; Mesentery; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger | 2003 |
Sodium-activated potassium conductance participates in the depolarizing afterpotential following a single action potential in rat hippocampal CA1 pyramidal cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Extracellular Space; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Lithium; Male; Neural Conduction; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2004 |
Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anisomycin; Bicuculline; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Emetine; Excitatory Amino Acid Antagonists; Learning; Long-Term Potentiation; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channels; Propanolamines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels | 2005 |
Nuclear factor-kappaB activation by reactive oxygen species mediates voltage-gated K+ current enhancement by neurotoxic beta-amyloid peptides in nerve growth factor-differentiated PC-12 cells and hippocampal neurones.
Topics: 4-Aminopyridine; Actin Cytoskeleton; Amyloid beta-Peptides; Animals; Blotting, Western; Calcium; Cell Differentiation; Cells, Cultured; Charybdotoxin; Chelating Agents; Cnidarian Venoms; Dactinomycin; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; GAP-43 Protein; Hippocampus; Membrane Potentials; Nerve Growth Factor; Neurons; NF-kappa B; Patch-Clamp Techniques; PC12 Cells; Peptide Fragments; Peptides; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Synthesis Inhibitors; Rats; Reactive Oxygen Species; Tetraethylammonium; Time Factors; Vitamin A | 2005 |
Optical monitoring of progressive synchronization in dentate granule cells during population burst activities.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Calcium; Carboxylic Acids; Cell Count; Dentate Gyrus; Diagnostic Imaging; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Membrane Potentials; Monitoring, Physiologic; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Rats; Rats, Wistar; Reaction Time | 2005 |
The effect of BAPTA and 4AP in scala media on transduction and cochlear gain.
Topics: 4-Aminopyridine; Acoustic Stimulation; Animals; Chelating Agents; Cochlear Duct; Cochlear Microphonic Potentials; Egtazic Acid; Guinea Pigs; Iontophoresis; Potassium Channel Blockers | 2006 |
Late N-methyl-D-aspartate receptor blockade rescues hippocampal neurons from excitotoxic stress and death after 4-aminopyridine-induced epilepsy.
Topics: 4-Aminopyridine; Animals; Cell Count; Cell Death; Chelating Agents; Disease Models, Animal; Dizocilpine Maleate; Drug Interactions; Egtazic Acid; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Time Factors | 2005 |
Serotonin depolarizes the membrane potential in rat mesenteric artery myocytes by decreasing voltage-gated K+ currents.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Calcium; Chelating Agents; Egtazic Acid; Ionophores; Male; Membrane Potentials; Mesenteric Arteries; Muscle Cells; Nystatin; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Serotonin; Tetraethylammonium | 2006 |
Endothelium-independent vasodilation induced by kolaviron, a biflavonoid complex from Garcinia kola seeds, in rat superior mesenteric arteries.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channels, L-Type; Charybdotoxin; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Flavonoids; Garcinia kola; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Mesenteric Artery, Superior; Muscle Contraction; Neurotoxins; Organ Culture Techniques; Phenylephrine; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Wistar; Seeds; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
An excitatory loop with astrocytes contributes to drive neurons to seizure threshold.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Chelating Agents; Egtazic Acid; Entorhinal Cortex; Excitatory Amino Acid Agonists; Glutamic Acid; Guinea Pigs; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Seizures | 2010 |
Dynamic Kv4.3-CaMKII unit in heart: an intrinsic negative regulator for CaMKII activation.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chelating Agents; Edetic Acid; Egtazic Acid; Heart Diseases; HEK293 Cells; Humans; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Shal Potassium Channels | 2011 |
Effects of axonal topology on the somatic modulation of synaptic outputs.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Axons; Biophysics; Calcium; Computer Simulation; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Hippocampus; Male; Models, Neurological; Nerve Net; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channel Blockers; Presynaptic Terminals; Rats; Rats, Wistar; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2012 |
Rapid homeostatic plasticity of intrinsic excitability in a central pattern generator network stabilizes functional neural network output.
Topics: 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Brachyura; Chelating Agents; Cyclosporine; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Female; Ganglia, Invertebrate; Homeostasis; Male; Motor Neurons; Nerve Net; Neuronal Plasticity; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; RNA, Messenger; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2012 |
Quercetin inhibits depolarization-evoked glutamate release in nerve terminals from rat cerebral cortex.
Topics: 4-Aminopyridine; Animals; Antioxidants; Calcium; Cerebral Cortex; Chelating Agents; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Glutamic Acid; Male; Membrane Potentials; Potassium Channel Blockers; Potassium Chloride; Quercetin; Rats; Rats, Sprague-Dawley; Sodium; Synaptosomes | 2013 |
Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats.
Topics: 4-Aminopyridine; Animals; Calcium; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hesperidin; Hippocampus; Kainic Acid; Male; Membrane Potentials; Neuroprotective Agents; Neurotoxicity Syndromes; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Synaptosomes; Tetrodotoxin | 2015 |
Correlation between the increased release of catecholamines evoked by local anesthetics and their analgesic and adverse effects: Role of K(+) channel inhibition.
Topics: 4-Aminopyridine; Analgesics; Anesthetics, Local; Animals; Calcium Chelating Agents; Catecholamines; Drug Interactions; Egtazic Acid; Electric Stimulation; In Vitro Techniques; Male; Potassium Channel Blockers; Prefrontal Cortex; Rats; Rats, Wistar; Spinal Cord; Tritium | 2016 |